Digital Commons Network^™

Preparation Of Supramolecular Amphiphilic Cyclodextrin Bilayer Vesicles For Pharmaceutical Applications, Kate E. Frischkorn

Master's Theses

Recent pharmaceutical developments have investigated using supramolecular nanoparticles in order to increase the bioavailability and solubility of drugs delivered in various methods. Modification of the carbohydrate cyclodextrin increases the ability to encapsulate hydrophobic pharmaceutical molecules by forming a carrier with a hydrophobic core and hydrophilic exterior. Guest molecules are commonly added to these inclusion complexes in order to add stability and further increase targeting abilities of the carriers. One such guest molecule is adamantine combined with a poly(ethylene glycol) chain. Vesicles are formed by hydrating a thin film of amphiphilic cyclodextrin and guest molecules in buffer solution that mimics physiological …

Real-Time Object Removal In Augmented Reality, Tyler Dahl

Master's Theses

Diminished reality, as a sub-topic of augmented reality where digital information is overlaid on an environment, is the perceived removal of an object from an environment. Previous approaches to diminished reality used digital replacement techniques, inpainting, and multi-view homographies. However, few used a virtual representation of the real environment, limiting their domains to planar environments.

This thesis provides a framework to achieve real-time diminished reality on an augmented reality headset. Using state-of-the-art hardware, we combine a virtual representation of the real environment with inpainting to remove existing objects from complex environments.

Our work is found to be competitive with previous …

Orbital Optimization Of Interplanetary Trajectories With Environmental Perturbations, Eric S. Woods

Master's Theses

For a detailed analysis of orbital optimization, it is desired to incorporate a spacecraft environment model in order to have maximum confidence that the analysis will produce an accurate trajectory. Such a model requires the addition of orbital perturbations, or small forces acting on the spacecraft throughout its trajectory that can eventually accumulate in large distances over time. The optimization method that this thesis is concerned with is STOpS (Spacecraft Trajectory Optimization Suite), a Matlab optimizer created by Timothy J. Fitzgerald that utilizes an Island Model Paradigm with five different optimization algorithms. STOpS was originally built to model trajectories with …

A Modified Multiphase Boost Converter With Reduced Input Current Ripple: Split Inductance And Capacitance Configuration, Zoe M. Hay

Master's Theses

This thesis presents the simulation, design, and hardware implementation of a modified multiphase boost converter. Converter design must consider noise imposed on input and output nodes which connect to and influence the operation of other devices. Excessive noise introduces EMI which can damage sensitive circuits or impede their operation. High ripple current degrades battery lifetime and reduces operating efficiency in connected systems such as PV arrays. Converters with high ripple current also experience greater peak conduction loss and require larger components. A two-phase implementation of a modified boost converter demonstrates the input current filtering benefits of the modified topology with …

Design And Verification Of A Labview Automated Antenna Radiation Pattern Measurement System, Dylan C. Bloom

Master's Theses

In 2014, Toyon Research Corporation donated a 6’x6’x8’ anechoic chamber to the Cal Poly EE department to advance student education in the areas of antennas and wireless communications. An anechoic chamber is a room designed to suppress electromagnetic radiation reflections so that accurate measurement of radio frequency (RF) systems such as wireless radios and antennas can take place. Despite the fact that Cal Poly already has a larger anechoic chamber, primarily used for antenna characterization, it is the purpose of this project to design, code, and equip the new chamber so that it performs at least as good, or better …

Bird Abundance At Bird Feeders In Response To Temperature, Wind Speed And Precipitation During The Winter Season, Siddhant Kahal

Master's Theses

The goal of this project is to explore how 23 different bird species respond to 3 climatic attributes. These attributes are lower than average temperatures, wind speed and precipitation level. Information about the bird species and all of the data associated with them is provided by Project FeederWatch (PFW). This is a citizen based survey study that provides key information about bird species abundance through the use of backyard and community feeders. The study volunteers from across the United States and Canada monitor these bird feeders and note important information about the species such as the number of individuals seen. …

Finite-Difference Modeling Of The Batch Process Smoldering Combustion Of Wastewater, Laura H. Kawashiri

Master's Theses

A MATLAB model was developed for the smoldering combustion of wastewater in the context of a decentralized residential wastewater treatment appliance. Data from a batch process sewage smoldering experiment was simulated using implicit finite-difference approximations, assuming one-dimensional transient conductive heat transfer. The time-dependent temperature profiles within the column represented the main parameters of interest and were used to verify recoverable heat energy estimations. Given that the modeling method used for this thesis represents a unique approach, the assumptions and limitations of this model are thoroughly described in the context of reproducing results for other smoldering setups. A lack of convergence …

Hydrologic Response To Conifer Removal And Upslope Harvest In An Encroached Montane Meadow, Noël C. Fie

Master's Theses

Meadows are crucial components to larger river watersheds because of their unique hydrologic and ecological functions. Due to climate change, over grazing, and fire suppression, conifer encroachment into meadows has accelerated. In some western regions, nearly half of all meadow habitat has been loss due to conifer encroachment. Restoration of these hydrologic systems requires tree removal. Many studies exist that address the issue of conifer encroachment in montane meadows, however, few studies focus on the role that conifer removal plays on the encroaching meadow. Furthermore, few studies exist that document the hydrologic change from conifer removal and further restoration steps, …

Utilizing Permanent On-Board Water Storage For Efficient Deep Space Radiation Shielding, Nathan Ryan Gehrke

Master's Theses

As space technologies continue to develop rapidly, there is a common desire to launch astronauts beyond the ISS to return to the Moon and put human footsteps on Mars. One of the largest hurdles that still needs to be addressed is the protection of astronauts from the radiation environment seen in deep space. The most effective way to defend against radiation is increasing the thickness of the shield, however this is limited by strict mass requirements. In order to increase the thickness of the shield, it is beneficial to make mission critical items double as shielding material.

The human rated …

Acceleration Of Jaccard's Index Algorithm For Training To Tag Damage On Post-Earthquake Images, Kyle John Mulligan

Master's Theses

There are currently different efforts to use Supervised Neural Networks (NN) to automatically label damages on images of above ground infrastructure (buildings made of concrete) taken after an earthquake. The goal of the supervised NN is to classify raw input data according to the patterns learned from an input training set. This input training data set is usually supplied by experts in the field, and in the case of this project, structural engineers carefully and mostly manually label these images for different types of damage. The level of expertise of the professionals labeling the training set varies widely, and some …

Improving Introductory Computer Science Education With Draco, Mike Dongyub Ryu

Master's Theses

Today, many introductory computer science courses rely heavily on a specific programming language to convey fundamental programming concepts. For beginning students, the cognitive capacity required to operate with the syntactic forms of this language may overwhelm their ability to formulate a solution to a program.

We recognize that the introductory computer science courses can be more effective if they convey fundamental concepts without requiring the students to focus on the syntax of a programming language. To achieve this, we propose a new teaching method based on the Design Recipe and Code Outlining (DRaCO) processes. Our new pedagogy capitalizes on the …

Dynamics Simulation And Optimal Control Of A Multiple-Input And Multiple-Output Balancing Cube, Felix K. Haimerl

Master's Theses

This thesis document outlines the development of a multibody dynamics simulation of an actively stabilized multiple-input, multiple-output, coupled, balancing cube and the process of verifying the results by implementing the control algorithm in hardware. A non-linear simulation of the system was created in Simscape and used to develop a Linear Quadratic Gaussian control algorithm. To implement this algorithm in actual hardware, the system was first designed, manufactured, and assembled. The structure of the cube and the reaction wheels were milled from aluminum. DC brushless motors were installed into the mechanical system. In terms of electronics, a processor, orientation sensor, motor …

Neuro-Silicon Interface Of A Hirudo Medicinalis Retzius Cell Integrated With Field Effect Transistor, Kurt Christian Sjoberg

Master's Theses

The focus of this thesis was to measure the intracellular voltage of a living neural cell using a silicon transistor. The coupling of neurological tissues with silicon devices is of interest to the fields of neurology, neuroscience, electrophysiology and cellular biology. In previous work by Peter Fromherz, single neurons were successfully coupled to transistors [1]. This thesis aims to show proof of concept of the fabrication of a simple neuro-silicon interface using wafer processing methods currently available at Cal Poly. The types of transistors and cells used, the methods for dissecting and preparing the cells, the electrophysiology methods for validating …

Modeling The Spatially Varying Point Spread Function Of The Kirkpatrick-Baez Optic, Nathan Adelman

Master's Theses

Lawrence Livermore National Laboratory's (LLNL) National Ignition Facility (NIF) uses a variety of diagnostics and image capturing optics for collecting data in High Energy Density Physics (HEDP) experiments. However, every image capturing system causes blurring and degradation of the images captured. This degradation can be mathematically described through a camera system's Point Spread Function (PSF), and can be reversed if the system's PSF is known. This is deconvolution, also called image restoration. Many PSFs can be determined experimentally by imaging a point source, which is a light emitting object that appears infinitesimally small to the camera. However, NIF's Kirkpatrick-Baez Optic …

Influencing Exploration In Actor-Critic Reinforcement Learning Algorithms, Andrew R. Gough

Master's Theses

Reinforcement Learning (RL) is a subset of machine learning primarily concerned with goal-directed learning and optimal decision making. RL agents learn based on a reward signal discovered from trial and error in complex, uncertain environments with the goal of maximizing positive reward signals. RL approaches need to scale up as they are applied to more complex environments with extremely large state spaces. Inefficient exploration methods cannot sufficiently explore complex environments in a reasonable amount of time, and optimal policies will be unrealized resulting in RL agents failing to solve an environment.

This thesis proposes a novel variant of the Actor-Advantage …

Catheter Localization Utilizing A Sensor-Enabled Guidewire: Design Of A Proof-Of-Concept System, Adam Edward Evard

Master's Theses

The purpose of this thesis project was to develop a proof-of-concept system for tracking the tip of a catheter without an embedded electromagnetic sensor by utilizing a sensor enabled guidewire. The motivation for the project was a reduction fluoroscopy radiation dose for clinicians in the interventional cardiology lab and the extension of navigation technology to be used with a wider variety of interventional devices through the implementation of expanded capabilities of the Abbott MediGuide system. The focus of the project was on the development of a proof-of-concept system capable of using an external device to track relative guidewire and catheter …

Characterization Of Arterial Flow For Junctional Bleeding Control, Nick Bosio

Master's Theses

This study investigated reducing volumetric flowrate under steady flow conditions by varying lengths of compression with constant cross-sectional area and varying cross-sectional area reduction with constant length in order to better understand how to control junctional hemorrhaging. The hypotheses of this study were that length reduction will have little effect on volumetric flowrate and that cross-sectional area reduction would need to be approximately 80 percent in order to obtain bleeding control. The study found that length reduction has little effect on changing the flowrate. However, in order to obtain at least 80 percent reduction in flow, the area needs to …

Validation Of A 1d Algorithm That Measures Pulse Wave Velocity To Estimate Compliance In Blood Vessels, James Leung

Master's Theses

The purpose of this research is to determine if it is possible to validate the new 1D method for measuring pulse wave velocity in the aorta in vivo and estimate compliance. Arterial pressure and blood flow characterize the traveling of blood from the heart to the arterial system and have played a significant role in the evaluation of cardiovascular diseases. Blood vessel distensibility can give some information on the evolution of cardiovascular disease. A patient’s aorta cannot be explanted to measure compliance; therefore we are using a flow phantom model to validate the 1D pulse wave velocity technique to estimate …

Investigation On The Dissociative Photoionization Mechanism Of Furfural, Investigation Of The Absolute Photoionization Cross Sections Of Three Potential Propargylic Fuels, And Ab Initio Analysis On Potential Superbases Of Several Hyperlithiated Species: Li3f2o And Li3f2(Oh)N (N = 1, 2, 3), Matthew Winfough

Master's Theses

This thesis presents the study photoionization cross sections of three different propargylic biofuels; dipropargyl ether, propargyl alcohol, and propargylamine, in chlorine radical-initiated combustion experiments at the Chemical Dynamics Beamline (9.0.2) at the Advanced Light Source of the Ernest Orlando Berkeley National Laboratory in Berkeley, California. Additionally, the unimolecular dissociative photoionization mechanism of furfural was studied using photoelectron photoionization coincidence (PEPICO) spectroscopy at the vacuum ultraviolet beamline at the Swiss Light Source of the Paul Scherrer Institut in Villigen, Switzerland. Dissociation products and mechanisms for furfural were identified over a photon energy range of 10.9 to 14.5 eV. Lastly, a study …

Bi Or Multilingualism And Its Curriculum For Children With Sli, Jeongmin Ryou

Master's Theses

The purpose of this project, which is based on SLI children age 3-6, is to inspect the possibility of bi- or multilingualism on SLI children and to create a curriculum, which consists of six modules, accordingly. It includes a variety of visual and auditory materials for each module, offers well-tailored daily lesson, and helps children with SLI learn the target language simply and easily. This project provides tips for teachers and can be also referenced when a teacher creates his or her own curriculum. Each module is flexible and should be tailored to the individual, while also being facilitated to …

Incentives And Teacher Effort: Evidence From Lagos, Nigeria, Simileoluwa Adebajo

Master's Theses

According to recent research (Hattie, 2003), teachers contribute to around 30% of the overall variation in student achievement and success – more than any other influencing factor. This study seeks to understand how different types of incentives (monetary, near monetary and non-monetary incentives) influence the “effort” of public school teachers as perceived by the students in Lagos, Nigeria using a novel measurement tool – the teaching effectiveness survey – to measure the teachers’ outcomes. Using a randomized field experiment where students evaluate the changes in their teachers’ effort with a standard teaching effectiveness survey and differences in differences estimation, we …

Using Monetary Incentives To Support Female Entrepreneurship: An Experimental Test Of Monetary Incentives In Abuja, Nigeria, Imuetinyan Aiguwurhuo

Master's Theses

Gender gaps in entrepreneurship are a major problem everywhere, but especially in developing countries like Nigeria. Women across the world face high levels of discrimination and abuse. The process of empowering women in a society has the potential to boost economic growth and development. Inspired by the success of the Family Independence Initiative (FII), we designed a field experiment to estimate the impact of using monetary incentives to motivate female entrepreneurs in achieving their goals in collaboration with the National Center for Women Development (NCWD) in Abuja, Nigeria. Our results suggest that being in a peer support group, setting a …

Seeing Red: Analyzing Iucn Red List Data Of South And Southeast Asian Amphibians, Alexandra Gonzalez

Master's Theses

In the midst of the sixth mass extinction event which is currently underway, it appears that amphibians are one of the most impacted vertebrates. Over 6,500 amphibian species are listed on the IUCN Red List (an assessment tool which provides species’ conservation status, perceived threats, and distribution range). While it is well-known that populations under multiple stressors are more likely to undergo significant declines, there are little to no resources available for visualizing how these threats may work synergistically and interact within a species’ range. This is especially the case for Southeast Asian amphibians, which much less attention has been …

Mineral Warfare: The Dark Side Of Technology And International Mediation, Priyanka Basnyat

Master's Theses

Conflict surrounding the extraction and trade of natural resources is not an uncommon phenomenon. Especially in the case of the Democratic Republic of Congo (DRC), which has historically suffered from the negative impacts of the resource curse since their mineral wealth was first discovered by their Colonial administrators. The importance of Congo’s minerals has fluctuated over the years but has peaked during recent times, as their use in technological advancements are becoming more vital. The global demand for these mineral ores have sky rocketed and consequentially, the largely informal trade has benefitted certain rebel groups, playing a pivotal role in …

Female Risk Aversion: Experimental Evidence From Myanmar, O Mandalay

Master's Theses

Present literature shows that the risk tolerance of females is generally lower than that of males, but in some circumstances, it can exceed – when concerning the welfare of the offspring, for example. Many experiments and data suggest that the dynamics of female risk tolerance depend on context and type of rewards involved as well as cultural norms. In our experiment, holding the culture and the context fixed, we found that females took less risk than males. Our experiment was conducted in Myanmar using a lottery selection method to measure risk over five consecutive rounds. We found 1) female risk …

What’S At Steak? The Political Discourse Of Emissions Intensity And Implications Of Animal Agriculture, Kalyn Simon

Master's Theses

This thesis analyzes the international discourse of greenhouse gas emissions in relation to livestock production. Specific government ministries, research institutes, and multilateral organizations are framing a new strategy to mitigate emissions by using emissions intensity metrics. Emissions intensity is a ratio comparing emissions produced per unit of animal product as oppose to measuring absolute emissions. This research is acknowledged as a win-win scenario which allows for a reduction of greenhouse gas emissions while continuing production more efficiently. This thesis outlines the emergence of this metric in international discourse and the implications this shift has on the livestock sector globally. Ultimately, …

Energy And Water Use Analysis For The Greenbox System In Comparison With The A-Frame Glass Greenhouse, Junya Wu

Master's Theses

A greenbox horticultural system has been recently proposed and developed by VECNA (Cambridge, MA) and University of Connecticut (Storrs, CT) for intensive urban agriculture. It uses urban warehouses to house and operate many individual grow boxes, named greenboxes, and for each of boxes the climate is automatically controlled to provide the optimum growing conditions for specific plant species. This study was conducted to analyze the energy and water use of the newly proposed greenbox system, in comparison with a specific greenhouse. Energy and mass balance equations were applied to generate dynamic simulation models for both structures. Head lettuce was selected …

The Physiological And Perceptual Effects Of Wrist Cooling During Exercise In A Thermal Environment, Andres Almeraya

Master's Theses

No abstract provided.

Near Field Mixing Characteristics Of A Variable Density Non-Reacting Jet In A Hot Vitiated Crossflow, Kyle T. Linevitch Jr

Master's Theses

The mixing characteristics in the “extreme” near field of a non-reacting jet in crossflow were experimentally investigated in an environment relevant to gas turbine combustors. A turbulent jet was injected into a hot vitiated crossflow of combustion products at 1500K. Different jet-to-crossflow momentum flux ratios and jet-to-crossflow density ratios were studied using three different jet exit velocity profiles; a fully developed turbulent pipe flow with 4% turbulence intensity (TI), a top-hat flow with 8% TI, and a turbulent pipe-like flow with 40% TI. Center-plane scalar mixing of the jet and crossflow were investigated using measured temperature fields from planar laser …

The Relationship Between Stryd Power And Running Economy In Well-Trained Distance Runners 2018, Casey Austin

Master's Theses

A novel running wearable called the Stryd Summit footpod attaches to a runner’s right or left shoe and measures running power output. The developers of the product purport that the footpod’s power and form power measures may correlate with metabolic data gathered in a lab. PURPOSE: Explore the relationship between power output and running economy at threshold pace. METHODS: Seventeen well-trained distance runners, 9 males and 8 females, completed a running protocol at threshold pace. Participants ran two discontinuous four-minute stages: one with their self-selected cadence (SS), and one with cadence lowered by 10% (LC). Metabolic data, power, and form …