Digital Commons Network^™

Examining Influences On Undergraduate Athletic Training Students Career Decisions Post Graduation, Kerri E. Gavin

Master's Theses

Context: Career opportunities for athletic training students (ATSs) have significantly increased over the past few years. However, it commonly appears that ATSs are opting for a more diversified professional experience after graduation. With the diversity in available options, an understanding of career decision is imperative. Objective: The purpose of our study was to investigate, using the theoretical framework of socialization, the influential factors behind the post graduation decisions of the senior ATS. Design: Qualitative design using internet-based, structured interviews and follow-up semi-structured phone interviews. Setting: Web-based management system. Patients or Other Participants: 22 ATSs (16 females; 6 males), who graduated …

Implementation Of Physiologic Pressure Conditions In A Blood Vessel Mimic Bioreactor System, Kevin Mark Okarski

Master's Theses

ABSTRACT

Implementation of Physiologic Pressure Conditions in a Blood Vessel Mimic Bioreactor System

Kevin Mark Okarski

Tissue engineering has traditionally been pursued as a therapeutic science intended for restoring or replacing diseased or damaged biologic tissues or organs. Cal Poly’s Blood Vessel Mimic Laboratory is developing a novel application of tissue engineering as a tool for the preclinical evaluation of intravascular devices. The blood vessel mimic (BVM) system has been previously used to assess the tissue response to deployed stents, but under non-physiologic conditions. Since then, efforts have been made to improve the vessel and bioreactor’s ability to emulate in …

Finite Element Modeling Of Icd Lead Silicone Soft-Tips, Jose J. Lepe

Master's Theses

Although highly underutilized by the medical device industry, Finite Element Analysis (FEA) in the development of new technologies is gaining popularity as regulatory bodies such as the Food and Drug Administration (FDA) begin to require additional proof of safety through scientific methods. Non-linear FEA allows engineers to realistically simulate the mechanical behavior of implants as seen in the in-vitro, or in some cases, the in-vivo configurations. The work presented in this report investigates how computational methods can be used to simulate the interaction of a St. Jude Medical silicone soft-tip as it passes through a Peel-Away Sheath (i.e. introducer). In …

A Rapid Prototyping Method For Constructing A Complex Three-Dimensional Substrate, Kathryn Jacoba Hart

Master's Theses

Cell culturing on three-dimensional structures has increased the possibilities in tissue engineering and bioreactor research. These structures enable cells to differentiate, proliferate, mobilize, and function in a conformation that more accurately mimics in vivo conditions. Computer generated models aid in development and rapid alteration of three-dimensional cell substrates, defining their internal structure as well as their external morphology. The rapid transition from substrate design to a viable culture is imperative to quickly advance research in biomedical and tissue engineering applications.

The aim of this thesis is to investigate the feasibility of a rapid prototyping process by selectively cross-linking and assembling …

Time-Frequency Analysis Of Intracardiac Electrogram, Erik Brockman

Master's Theses

The Cardiac Rhythm Management Division of St. Jude Medical specializes in the development of implantable cardioverter defibrillators that improve the quality of life for patients diagnosed with a variety of cardiac arrhythmias, especially for patients prone to sudden cardiac death. With the goal to improve detection of cardiac arrhythmias, this study explored the value in time-frequency analysis of intracardiac electrogram in four steps. The first two steps characterized, in the frequency domain, the waveforms that construct the cardiac cycle. The third step developed a new algorithm that putatively provides the least computationally expensive way to identifying cardiac waveforms in the …

Preparation For Nerve Membrane Potential Readings Of A Leech, Laboratory Setup And Dissection Process, Jason Patrick Caulfield

Master's Theses

A well documented laboratory setup, leech preparation process, and bio-potential data recording process are needed. Repeatability and quality data recordings are essential and thus dictate the requirements of the laboratory setup and processes listed above. Advances in technology have both helped and hindered this development. While very precise equipment is required to record the low voltage bio-potentials, noisy electronic equipment and wires surrounding the work area provide high levels of interference. Proper laboratory setup and data recording processes, however, limit the unwanted interference. Quality data can only be recorded from a properly handled and prepared leech subject. Proper setup and …

Preparation And Characterization Of Electrospun Poly(D, L-Lactide-Co-Glycolide) Scaffolds For Vascular Tissue Engineering And The Advancement Of An In Vitro Blood Vessel Mimic, Tiffany Richelle Pena

Master's Theses

PREPARATION AND CHARACTERIZATION OF ELECTROSPUN POLY(D,L-LACTIDE-CO-GLYCOLIDE) SCAFFFOLDS FOR VASCULAR TISSUE ENGINEERING AND THE ADVANCEMENT OF AN IN VITRO BLOOD VESSEL MIMIC

Tiffany Richelle Peña

Currently, an estimated 1 in every 3 adult Americans are affected by one or more cardiovascular complications. The most common complication is coronary artery disease, specifically atherosclerosis. Outcomes of balloon angioplasty treatments have been significantly improved with the addition of drug eluting stents to the process. Although both bare metal and drug eluting stents have greatly increased the effectiveness of angioplasty and decreased the occurrence of restenosis, several complications still exist. For this reason, the stent …

Factors In Bmi Increase Among Multicultural Freshmen., Leah Haritan

Master's Theses

This observational research examines body mass index (BMI) changes in multicultural freshmen attending a large public urban university. It explores factors associated with BMI increase and investigates behavior changes and perceptions related to diet and body weight. The study utilizes an online survey distributed in November 2007 and again in April 2008. All 3,260 freshmen were eligible to participate. Initial response rate was 23%; 44% of initial respondents completed both surveys (N = 337). Results revealed a significant increase in BMI for on-campus residents, Caucasians, and males (P < 0.05). Decreased vegetable intake was associated with a BMI increase of less than one (P < 0.05). Fruits and vegetables were perceived by most as healthful; their high cost, and limited variety and availability on campus were deemed potential barriers to intake. Freshman weight gain may be a function of gender, residence, and ethnicity, and deserves further examination.

A Vitreoretinal Surgery System Fluidics Failure Modes And Effects Analysis, Jennifer Ann Grega

Master's Theses

Eyesight is something that is vital to all human beings. The concept of vitreoretinal surgery is an amazing achievement of modem medicine to help treat patients that might otherwise be blind. Vitreoretinal surgery has enhanced and restored vision in numerous individuals due to the forefront of new instrumentation and surgical techniques. As a manufacturer of surgical equipment it is critical that an in depth analysis of potential failure modes is completed and the necessary mitigations are put in place. A complete failure mode and effects analysis on the fluidics sub-module of a vitreoretinal surgery system is an imperative part to …

Cytokine Expression By T. Helper Cells Responding To Stress, Dina Zanetti

Master's Theses

Stress causes alterations to the immune system. These alterations have lead to increased susceptibility to antigens. The present study explores shifts in T helper (TH) cell balance (TH1 and TH2), through their cytokine expression. This study was performed in three phases, and focused mainly on animals subjected to a 10 day a chronic unpredictable stress paradigm. Phase one used ELISAs to confirm the cytokine profile produced from TH 1 and TH2 murine cell-lines. Phase two used SDS PAGE and Western Immunoblotting to show that splenocytes from Long Evan's Hooded rats subjected to the stress paradigm, had decreased in intercellular in …

Going To Nowhere : Narratives Of Patagonian Exploration, Mark W. Bell

Master's Theses

Since its discovery on Magellan's circumnavigation, Patagonia has been treated differently than any other region in the world. Effectively, Patagonia has been left empty or vacated by the North. But this emptiness and blankness have compulsively attracted curious travel writers who have filled the emptiness of Patagonia with self-reflexive projections. From Charles Darwin and W.H. Hudson to Bruce Chatwin and Paul Theroux, Northern commentators have found in Patagonia a landscape that accommodates their desire for self-reflexivity and self-consciousness. Thus, Patagonia has been simultaneously filled and evacuated by the Northern mind. As a result, Patagonia has become increasingly about the self …

Assessment Of Middle School Students' Cognitive Performance On Piagetian Tasks Requiring Formal Abstract Thinking Processes, Marilyn L. Mcclaskey

Master's Theses

Digitized thesis

An Examination Of The Compressed Work Week In A Continuous Operation, Mark Tippins

Master's Theses

No abstract provided.

Shakespeare And Astrology, William Bruce Smith

Master's Theses

The popular ity of astrology in Elizabethan England is ref lected by the large number of references to it in the works of William Shakespeare. The majority of astrological references in the Shakespearean canon are "commonplaces" and do not add signif icantly to our understanding of his work, although they are of interest in studying exactly how much astrological knowledge he possessed. There are astrological references in the plays, however, that are of significance in the study of character in Shakespeare. In certain plays (Romeo and Juliet, The Winter' s Tale) a judgement concerning various individuals ' inner nobility may …

Aldehydic Transition State Analogue Inhibitors Of Α-Chymotrypsin, Alexandra Constance Cheerva

Master's Theses

No abstract provided.

The Origin Of Pragmatism In William James, Charles A. Nash

Master's Theses

No abstract provided.

An Attempt To Appraise The Standing Of Biology As A Subject Of Instruction In High School, Mary Fidelis

Master's Theses

No abstract provided.