Digital Commons Network^™

Drivers Of Microparticles Abundance In Freshwater Fish And Macroinvertibrates, Elizabeth Kazmierczak

Master's Theses

Anthropogenic microparticles (MP) (i.e., particles < 5 mm) are defined as materials of manufactured origin found in the environment. They are widespread and a rapidly emerging global contaminant. MP include microplastics (< 5 mm), as well as other microfibers or particles, which can be synthetic, semi-synthetic and non-synthetic. Rivers are a critical source of plastics to oceans, and MP within rivers are retained in part though biological processes, including ingestion. MP ingestion by freshwater biota varies by proximity to point sources (e.g., wastewater treatment plants; WWTP), overall environmental concentrations, and trophic level and functional feeding groups, but few studies have examined these factors together. In our first study we examined fish collected in the North Shore Channel of the Chicago River to determine MP abundance within organisms. We then compared trophic position (i.e., δ15N) and proximity to a WWTP. With all species combined, MP concentration were not significantly different across study sites, but stable isotopes increased downstream. Considered individually, MP abundance relative to WWTP proximity varied by species, which we attributed to habitat preference and mobility. In a second project, we collected macroinvertebrates from three different watersheds in North America and compared the abundance of MP in macroinvertebrates to concentration within the environment (i.e., water column, surface, and benthic). Functional feeding groups were a significant predictor in the amount of microparticles found in macroinvertebrates. Additionally, the concentration of water column microparticles showed a positive relationship with all macroinvertebrate’s microparticle abundance. Results will aid in understanding the ecological impacts of MPs on aquatic food webs and the pathways in which they can enter.

“Get Out Of The House Before It Kills You”: Haunted Housewives And The Feminist Gothic In Ira Levin’S Rosemary’S Baby And The Stepford Wives, Sarah Jeffries

Master's Theses

Ira Levin’s works Rosemary’s Baby and The Stepford Wives have been cultural touchstones since their releases in 1967 and 1972, respectively, with their legacy as iconic American horror stories cemented by successful film adaptations. At the surface level, these stories can be read as tales about unfortunate housewives that face unusual horrors. Rosemary Woodhouse finds herself trapped in a gothic New York City apartment building, the Bramford, where her husband and neighbors collude to force her to carry and birth Satan’s son, like a perverse Virgin Mary. Joanna Ebert is similarly stuck in suburban Stepford, Connecticut where she discovers the …

The Skin Microbiome And Cutaneous T-Cell Lymphoma, Gail Hillary Lantaca Enriquez

Master's Theses

Skin microbiota is associated with disease activity in cutaneous T-cell lymphoma (CTCL). A common treatment for CTCL, narrowband ultraviolet B (nbUVB) phototherapy, has shown to shape the skin microbiome in association with disease improvement in other skin disorders such as atopic dermatitis. To assess the effect of nbUVB phototherapy on the skin microbiome, we performed a longitudinal analysis of skin samples of CTCL patients receiving nbUVB. We found that the treatment led to increased bacterial diversity and reduced abundances of Staphylococcus aureus and Staphylococcus lugdunensis, both bacteria known to be pathogenic. These findings imply that nbUVB treatment changes the skin …

Associations Between Neighborhood Factors And Adherence In Youth With Spina Bifida: The Mediating Role Of Parental Stress And Youth Internalizing Symptoms, Breana Lyn Bryant

Master's Theses

Spina bifida (SB) is a birth defect that impacts physical, medical, and neuropsychological functioning. Physical complications like hydrocephalus and bladder dysfunction require daily adherence to complex medical regimens. Additionally, youth with SB are more likely to have symptoms of anxiety and depression which can impact their ability to master their regimens. Evidence in other pediatric populations have examined the impact of family factors, like parental stress, and individual-level predictors of self-management outcomes, yet few have examined how the broader context, like neighborhoods, impact outcomes. Therefore, the current study examined (1) the level of the neighborhood vulnerability and acute healthcare services …

Lactobacillus-Mediated Phage Induction And Inhibition Of Growth Of Escherichia Coli, Natalie Stegman

Master's Theses

Bacterial species inhabit both the “healthy” and symptomatic female urinary tract. Lactobacillus species are frequently dominant members of the healthy urinary tract microbiota (urobiome), and thus have been associated with the lack of lower urinary tract symptoms (LUTS). In contrast, colonization by Escherichia coli is the most common cause of urinary tract infections (UTIs). Prior research has found that strains of Lactobacillus can inhibit the growth of uropathogens such as E. coli as well as vaginosis-associated pathogens. Investigations into the means by which lactobacilli inhibit pathogenic growth have primarily focused on their production of hydrogen peroxide (H2O2) and lactic acid, …

The Effect Of Environmental Pollutants On The Spotted Turtle Gut Microbiota, Roza Gawin

Master's Theses

Heavy metals are a common pollutant from many industrial processes. In addition to the various diseases that these pollutants cause, they can also affect the composition and structure of the gut microbiome of many organisms which is in many cases associated with overall organism health. The effect of these pollutants on the gut microbiota of the spotted turtle is unknown. Here we characterize the gut microbiome of the spotted turtle and explore the effect of various environmental pollutants on its composition. We found significant differences in the composition of the gut microbiome based on turtle sampling location (geographic), turtle sampling …

Understanding Teachers’ Responses To Parental Demands In The Midst Of Competing Responsibilities, Kathryn Battafarano

Master's Theses

This study builds upon a plethora of educational research and focuses specifically on middle school grade level teachers. I predominantly utilized qualitative interviews to understand how teachers respond to parental demands; these answers were supplemented by some quantitative data about their schools. The study configures information about teachers’ school environments and requirements, teachers’ interactions with parents, and how teachers deal with parental demands in relation to other demands and requirements. Effort was made to investigate how teacher experience, teaching style, and subject matter as well as school type (e.g., socio-economic makeup of the school) and school location influence parental demands …

Queer Futurity Needs Queer Grief: An Analysis Of The U.S. Public Response To Queer Loss, Jordan Nicole Mckinnon

Master's Theses

Grief is an inevitable part of the human experience. However, communities, especially those where a majority of members have disprivileged identities, experience disenfranchised grief, or grief that is not openly acknowledged, socially accepted, or publicly mourned. Members of the LGBTQIA+ (lesbian, gay, bisexual, transgender, queer, intersex, asexual, plus other identities not encompassed in the acronym) community, and their allies can experience a type of disenfranchised grief known as queer grief. I argue that everyone, not just allies and members of the LGBTQIA+ community, should recognize and publicly acknowledge queer grief, because if queer lives lost are not recognized as worthy …

Investigation Of Temperature, Solution Strength, And Applied Stress Effects On Cation Exchange Processes In Different Geosynthetic Clay Liner Products, Kendra Fuller

Master's Theses

An extensive laboratory test program was conducted to analyze and compare the cation exchange processes in three different varieties of sodium bentonite (Na-B) geosynthetic clay liners (GCLs) over increased conditioning durations up to 32 days and investigate the effects of temperature, solution strength, and applied stress. The goal of this test program was to establish whether the variables of temperature, solution strength, and applied stress improved or degraded the engineering properties of GCLs in laboratory testing and municipal solid waste (MSW) landfill applications. The GCLs were conditioned in liquids of increasing ionic strength, using deionized water and 2, 50, and …

History & Evolution Of Plastic Mulching Technology: An Ethnography Of California Strawberry Plasticulture, Kalea Conrad

Master's Theses

This ethnography draws on key informant interviews and participant observation to produce a case study about plastic mulching as an important industry standard in specialty crop production. It documents the historic adoption and present role of plastic mulching technology in California strawberry production and addresses the characteristics of commercial standard management that inhibit the adoption of alternative mulching practices. It complements extensive research on strawberry pathology and fumigation, breeding innovations, fertilizer and pesticide treatments, and maximization of yields to incorporate participants’ lived experiences and knowledge of mulch origins, the technology adoption process, mulch benefits and drawbacks, the state of agricultural …

Dual Base Sige Is-Hbt For Use In Biosensing Applications, Liam Stephen Hayes

Master's Theses

The proposed research is for a novel SiGe-based Ion-Sensitive Dual Hetero-junction Bipolar Transistor (IS-HBT) to be used in both trans-dermal biological sensing as well as Lab-on-Chip (LOC) applications. The end goals for the device designed are two: For one, the research done for this work will be used to substantiate the claims made by Zafar et al. [1] that an HBT-style structure is better suited for biosensing application rather than a conventional Field Effect Transistor (FET) based geometries. Secondly, it provides the final element to be integrated along with a selectivity membrane, as well as with a reverse-iontophoresis system to …

Validation Of Mobile Devices In Arbitrary Locations Against Force Plate Standard For Balance Assessment, German J. Ellsworth

Master's Theses

With balance assessment being essential to the prediction of fall risk and detection and assessment of motor disorders, increasing clinical accessibility to objective balance metrics is essential. Work has been done validating center of mass (COM) acceleration metrics against well regarded force plate center of pressure (COP) position standards for mobile device data acquisition systems, but most research is restricted to devices being close to the COM or strapped in a harness configuration. Through the use of rigid body kinematics and the inverted pendulum model, this study develops novel methodology for calculating COM acceleration using mobile devices in arbitrary positions, …

Barriers To And Solutions For Fuel Treatments In The Central California Coast Ranges, Sierra Dawn Lyman

Master's Theses

In recent years, the Western United States has experienced an increase in fire activity due to multiple factors, including anthropogenic climate change, historical forest management focused on suppression, and the expanding wildland urban interface (WUI). In response, California is working to accelerate the pace and scale of forest management and fire hazard reduction efforts. Although fuel treatment projects are being implemented, they often encounter various barriers. While existing literature highlights these barriers, it tends to overlook the solutions being applied in practice to overcome them. Using an ethnographic approach that includes key informant interviews and participant observation in four sites …

A Data-Driven Framework For Analyzing And Predicting Social Media Engagement During Rumor Propagation, Joseph E. Faza

Master's Theses

The spread of rumors on social media has become a significant concern, as platforms like X (formerly known as Twitter) enable rapid dissemination of unverified information. These rumors can shape public perception and behavior, making it crucial to understand the dynamics of their spread. The main objective of this study is to explore how users interact with rumor-related tweets and identify key factors that predict tweet engagement. By analyzing tweets from seven different rumor events, this research aims to uncover patterns in user engagement and provide insights into the spread of misinformation. The study utilized a dataset of tweets from …

Of Geese And Grass: Investigating Impacts Of Brant Grazing On Eeelgrass, Dakota L. Osborne

Master's Theses

Grazing pressure is important in structuring plant communities, particularly in aquatic environments. Eelgrass (Zostera marina), a keystone species in estuaries across North America, is experiencing widespread population declines. As a keystone species, eelgrass provides numerous important functions, including: 1) water filtration, 2) sediment stabilization, 3) providing refuge and nursery habitat for numerous species, and 4) carbon sequestration. Benefits which could be lost if eelgrass beds continue to diminish. California has experienced some of the greatest eelgrass declines, and Morro Bay, CA experienced a 96% decrease in eelgrass from 2007 to 2017. Most studies to date have examined bottom-up …

Development Of Extruded Puffed Snack Utilizing Carrot Pomace, Bean Flour, And Rice Starch As Primary Ingredients, Julia Zoe

Master's Theses

Every year, the carrot industry worldwide wastes up to 50% of carrots as raw material due to processing (Šeregelj et al., 2020). When carrots are juiced, the remaining fibrous pulp is often discarded as carrot pomace. In order to redirect this food waste, the first objective of this research was to optimize formulations for an extruded puffed snack that is most similar to commercially available puffed snacks, utilizing baby lima bean flour and carrot pomace

Hardness (kg), cross-sectional expansion ratio, bulk density (g/cm³), moisture content (%), water activity, specific mechanical energy (kJ/kg), carotenoid concentration (ppm), and total dietary …

Survey Of Soilborne Pathogens Infecting Strawberry In Oxnard, California & Effect Of Planting Date And Chill Treatment On Yield Of Strawberry, Samantha Z. Simard

Master's Theses

Survey to quantify the frequency of the five main pathogens (Macrophomina phaseolina, Fusarium oxysporum f. sp. fragariae races 1 and 2, Verticillium dahliae, and Phytophthora spp.) infecting strawberry in the Oxnard growing district of California. M. phaseolina was the most prevalent pathogen detected in diseased plants in the Oxnard growing district, present in 67.6% of samples positive for at least one pathogen. F. oxysporum f. sp. fragariae race 1 (35.3%), V. dahlia (8.8%), F. oxysporum f. sp. fragariae race 2 (5.9%) and Phytophthora spp. (2.9%) followed at lower prevalence. Associations were found between fewer drip irrigation lines …

Assessment Of Mediterranean Diet Adherence Using The Kidmed Diet 2.0 Tool: College Student Questionnaire, Nakia Cyrice Hilton

Master's Theses

The Mediterranean Diet has garnered increasing popularity due to its multifaceted health benefits. The MedDiet enhances well-being across all age groups, emphasizing high consumption of fruits, vegetables, legumes, nuts, olive oil, and whole grains and moderate fish, poultry, and dairy intake. Recent research underscores the significant impact of Mediterranean diet adherence on college students' physical and mental health. The diet's emphasis on nutrient-dense foods rich in vitamins, minerals, and antioxidants supports cognitive function, which is pivotal for academic performance. Moreover, the abundant presence of healthy fats, particularly from olive oil and fatty fish, may contribute to improved mood regulation, potentially …

Supervised Classification Modeling On Louisiana Medicaid Data: A Comparative Study, Yead Rahman

Master's Theses

This thesis systematically optimizes and compares state-of-the-art supervised classification models for Louisiana Medicaid data targeting clinical services, COVID-19 infection, and tobacco use. These target variables are critically important as they represent key health outcomes and behaviors among Medicaid enrollees in Louisiana, a population often characterized by poverty and limited access to education. This study applies advanced machine learning techniques to identify the best model for multinomial and binary classification tasks. These include models such as Logistic Regression, XGBoost, AdaBoost, Random Forest, Decision Tree, Artificial Neural Networks, and Naïve Bayes. Extensive tuning of the hyperparameters and optimization of each classifier were …

Adherence To Mediterranean Diet Principles In Minority College Students, Bridgette Lorraine Barbre

Master's Theses

Every year, millions of young adults attend college. The Centers for Disease Control and Prevention (CDC) lists heart disease and diabetes as the top health concerns for minority Americans. African American and Hispanic/Latino communities could see a reduction in illness risk by promoting physical activity and healthy eating habits such as the Mediterranean Diet. Research indicates that young adults may benefit significantly from taking charge of their eating habits at the crucial point in their transition from high school to college. By determining the dietary patterns of minority college students, as related to the Mediterranean diet principles, this study intends …

Oral Nutritional Supplement Prescription And Adherence Perspectives, Kristyn Bordelon Hood

Master's Theses

Oral nutritional supplements (ONS) are nutrient-dense beverages that aid in meeting the nutrient needs of patients. Recent research has indicated that patient adherence to prescribed nutritional supplements may depend on palatability, tolerance, and taste fatigue. Registered Dietitian Nutritionists (RDNs) are healthcare professionals who may prescribe these supplements directly or make recommendations to the patient’s physician for a prescription, thereby influencing patient adherence. Little research has been documented regarding taste fatigue and the influences of the RDN’s decisions on patient adherence to nutritional supplement adherence. The purpose of this study was to gain an understanding of the perspectives of nutrition professionals …

Identifying The Interactors Of Otud6b-2 That Are Important For Its Function On C-Myc, Farah Albatsh

Master's Theses

The complexity of molecular signaling pathways, particularly in cancer research, has made the proto-oncogene c-Myc a key focus due to its role as a master regulator of cellular processes such as growth, division, and apoptosis. Dysregulation of c-Myc is linked to various cancers, making it a highly sought therapeutic target despite challenges in directly inhibiting its function. Recent efforts have shifted towards indirect targeting methods, including BET inhibitors, cyclin-dependent kinase inhibitors, and siRNA formulations. A novel approach using PROTACs and the investigation of c-Myc-specific deubiquitinases (DUBs) has shown potential, particularly the emerging player OTUD6B-2. This study aims to identify and …

Development Of A Urothelial Cell Line Expressing A Caspase-1 Biosensor To Measure Cellular Inflammatory Responses To Potential Uropathogens, Nikita Riya Kesav

Master's Theses

Urinary tract infections are one of the most common bacterial infections, historically implicating Escherichia coli as the causative pathogen. However, it is now known that there are a variety of bacteria that exist within the urinary tract, acting as either beneficial uroprotectives or opportunistic uropathogens. Furthermore, there are significant gaps in our understanding as to how these bacteria interact with the urothelium and what role each plays in maintaining or disrupting homeostasis. Research has shown that Toll-like receptor 4 (TLR4) signaling and Nod-like Receptor Protein 3 play a role in inflammasome activation during infection, triggering caspase-1 activation and inducing release …

The Anti-Inflammatory Properties Of Exopolysaccharide From Bacillus Subtilis, Nikolay Todorov

Master's Theses

Commensal microorganisms can be used therapeutically to ameliorate a variety of diseases. The laboratory of Dr. Katherine L. Knight studies these therapeutic properties in the commensal microorganism known as Bacillus subtilis. Previously, the Knight lab has demonstrated that B. subtilis can protect against colitis caused by Citrobacter rodentium suggesting that B. subtilis possesses anti-inflammatory properties. These properties are specific to the polysaccharide capsule of the microorganism known as exopolysaccharide or EPS. EPS can be produced and purified for study. EPS has been demonstrated to be protective in a variety of diseases such as allergic eosinophilia, sepsis, Graft versus Host disease, …

Characterization Of Cd11c-Expressing Gut-Associated T Cells, Ana Cvetkovic

Master's Theses

Our immune system is a remarkable defense network that protects our bodies from a range of threats. Its’ intricate machinery comprises of messenger and effector cells that work together to coordinate an effective immune response. Traditionally, T lymphocytes have been considered effectors: they receive instructions from messengers, known as Antigen Presenting Cells (APCs), that alter T-cell activation state and behavior. In the gut, Dendritic Cells (DCs) are the APCs that most often instruct T cells. To accomplish their messenger role, DCs express CD11c at high levels, a surface marker involved in cell-to-cell signaling and phagocytosis. As such, CD11c expression has …

Development Of Targeted, Statin Loaded Nanoparticle Delivery Systems, Stephanie Judkins

Master's Theses

Statins lower endogenous production of cholesterol through their inhibition of the mevalonate pathway. Lipophilic statins in particular exhibit anti-inflammatory effects at supraphysiological doses by preventing downstream signaling through small molecule GTPases. Interest lies in development of statins as anti-inflammatory therapeutics, however, achieving effective doses locally incurs serious off-target effects. Our goal was to develop and optimize a targeted delivery system to traffic these drugs to inflamed sites and unload the drug at effective concentrations while avoiding systemic exposure. Lipophilic statins (lovastatin, simvastatin, and atorvastatin) were incorporated into polymeric nanoparticles (NPs) due to their hydrophobicity. We have shown that statins released …

Investigating The Roles Of Sirtuins During Cvb3 Infection And Innate Immunity, Bridget M. Hulsebosch

Master's Theses

Coxsackievirus B3 (CVB3) is an enterovirus that chronically infects heart tissue, leading to dilated cardiomyopathy. However, no vaccines or antivirals exist for CVB3 infection or to treat CVB3-induced dilated cardiomyopathy, except for a heart transplant. Sirtuins (SIRTs), class III lysine deacetylases, have diverse and complex roles in cellular functions, contributing to energy production, NF-κB signaling, cell cycle regulation, and inflammation. Previous studies showed that SIRTs are essential for hepatitis B and A viral replication and regulate the IFN response during viral infection. However, the role of SIRT1 and 2 during CVB3 infection is entirely unknown. CVB3-infected SIRT1 and SIRT2 knockout …

Sport And Environmental Issues: Ncaa Division I Student-Athletes’ Personal Experiences, Ivanna M. Anderson-Villela

Master's Theses

While sport ecology is a growing category in sport management literature, there is a lack of research exploring athletes’ experiences regarding environmental issues, and the impacts environmental issues have on student-athletes. The present study qualitatively explored the personal lived experiences of eight NCAA Division I student-athletes regarding environmental issues with the aim of identifying potential influences on values and beliefs through social norms and understanding the student-athlete perspective. Thematic analysis identified 152 raw data themes and 19 higher order themes, which were organized into four central themes: awareness, care and concern from athletic departments, implications, and advocacy. Generally, student-athletes perceived …

A Qualitative Evaluation Of Speech Sound Disorder Treatment Apps For Children, Rachel G. Barnett

Master's Theses

This research examined 20 speech sound disorder (SSD) treatment apps’ features and costs as related to the feature matching process within speech-language therapy. Methods included the development of a 67-item SSD checklist and sorted into 9 categories, including linguistic levels, speech models, software customization, cost, game types, image types, technical elements, feedback types, and engagement and manipulation. Two independent reviewers applied the checklist to randomly selected contemporary apps available on both iPhones and iPads. App cost was capped at $25. Results indicated that app cost was not a good predictor of feature quantity and contemporary apps had some relevant feature …

Single-Caregiver Families: Using Lived Experiences To Build Effective Resilience And Protect Future Children Against Negative Outcomes, Andrew Chakalian

Master's Theses

Among many cited risk factors that disproportionately affect children who grow up in a single-caregiver family, adverse childhood experiences (ACEs) and related behavioral and health outcomes are some of the most significant. Comparatively, there has been a substantial gap in the research exploring protective factors that support healthy development for children with this family composition. The present study used a phenomenological methodology to explore how nine participants aged 18-25 viewed their childhood in a single-caregiver family. Through the use of semi-structured interviews, participants shared their experiences; analysis yielded four themes: (1) further dysfunction in the social system exacerbating the effects …