Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (1673)
- Medicine and Health Sciences (1052)
- Psychology (767)
- Life Sciences (740)
- Arts and Humanities (581)
-
- Engineering (542)
- Education (510)
- Physical Sciences and Mathematics (282)
- Dentistry (268)
- Sociology (244)
- Economics (191)
- History (184)
- Biomedical Engineering and Bioengineering (176)
- English Language and Literature (146)
- Biology (140)
- Business (127)
- Civil and Environmental Engineering (118)
- Clinical Psychology (111)
- Social Work (104)
- Oral Biology and Oral Pathology (96)
- Architecture (92)
- International and Area Studies (90)
- Microbiology (88)
- Political Science (86)
- Environmental Sciences (84)
- Kinesiology (83)
- Electrical and Computer Engineering (82)
- Ecology and Evolutionary Biology (81)
- Chemistry (79)
- Public Health (78)
- Institution
- Keyword
-
- College of Natural and Health Sciences (148)
- College of Performing and Visual Arts (79)
- Education (78)
- Theatre Arts and Dance (71)
- Theatre Arts and Dance Student Work (71)
-
- Virginia (66)
- Biological Sciences (56)
- Biological Sciences Student Work (56)
- Psychology (55)
- Nutrition (41)
- Gender (37)
- KiND Student Work (35)
- Kinesiology Nutrition and Dietetics (35)
- Dance (32)
- Women (32)
- History (31)
- Exercise (30)
- Stress (29)
- Biomechanics (28)
- College of Humanities and Social Sciences (28)
- Development (28)
- California (27)
- Migration (26)
- Nursing (26)
- Obesity (25)
- Depression (24)
- Machine learning (24)
- United States (24)
- Climate change (23)
- College students (23)
- Publication Year
- Publication Type
- File Type
Articles 1381 - 1410 of 6843
Full-Text Articles in Entire DC Network
A Restorative Resource: Dance-Based Non-Profits That Operate To Benefit Sex Trafficked Victims, Jessica Coleman
A Restorative Resource: Dance-Based Non-Profits That Operate To Benefit Sex Trafficked Victims, Jessica Coleman
Master's Theses
The purpose of this study was to bring awareness to dance-based non-profits which operate for the purpose of being a restorative resource for victims of sex trafficking. The goal of the researcher was to answer these five essential questions: Q1 What is the structure of the program? Q2 What are the outreach strategies being used to bring in participants? Q3 What kind of curriculum is being used in the program? Q4 What are the benefits that dance-based non-profits provide for victims of sex trafficking? Q5 How are the benefits of these programs being measured? This research was significant because with …
Participation In Ballroom Dancing: The Effects On The Social And Emotional Intelligence Of Adolescents, Ashley Baxter
Participation In Ballroom Dancing: The Effects On The Social And Emotional Intelligence Of Adolescents, Ashley Baxter
Master's Theses
The goal of this study was to determine the impact that ballroom dancing had on the social and emotional intelligence of adolescents as well as to examine which areas of social and emotional intelligence were most affected by participating in ballroom dancing. In the text Handbook of Social and Emotional Learning: Research and Practice, there are five competencies of social-emotional intelligence as defined by Celene E. Domitrovich et al.: “. . . self-awareness, self-management, social awareness, relationship skills, and responsible decision making” (6). The researcher examined the effect that ballroom dancing had on four out of five of these social-emotional …
Dignity And Respect In The Salsa Dance Classroom: Fostering Healthy Self-Esteem To Promote Compassion, Diana Sanchez
Dignity And Respect In The Salsa Dance Classroom: Fostering Healthy Self-Esteem To Promote Compassion, Diana Sanchez
Master's Theses
Many students that have attempted to take salsa dance classes often express their disillusionment in the way in which they are treated by salsa dance instructors. Salsa dance classes have the possibility to function to awaken in the student greater integration with the society in which people live, while stimulating actions, improving self-esteem, and self-confidence, improving vocabulary, awakening sensitivity, attenuating shyness, as well as increasing communicative and social skills. If the content of a course is well designed and delivered with an intentional student-centered approach, it can positively contribute to greater and more sincere learning. In this sense, the objective …
With A Little Help From My Friends: Determining The Role Of Physical Activity And Belonging In Retention Of First-Year University Students, Bryson Kelly
Master's Theses
There exists an issue facing colleges and universities across the United States. Roughly 29% of first-year students do not return for their second year of school. Previous research has shown a significant relationship between a student’s sense of belonging or fit within the university and their decision to continue enrollment (retention). Physical activity has also been shown to have a significant relationship with a sense of belonging. Therefore, the purpose of the present study was to determine if physical activity and sense of belonging predict retention of university students from their first year to their second year using a Relationships …
Rethinking Classical Ballet Pedagogy: Examining Advancements That Integrate A Modern Approach, Erika Lindblom
Rethinking Classical Ballet Pedagogy: Examining Advancements That Integrate A Modern Approach, Erika Lindblom
Master's Theses
The purpose of this research was to explore how recent advancements in technology and medical science have or have not pushed ballet pedagogy to evolve. Also examined were the principles of classical ballet that continue to be included despite current knowledge that these practices are outdated and may be unsafe. The 180-degree turn-out, dancing en pointe, and the grand plié were the specific areas of interest for this study. The following essential questions guided the research: Q1 What impact have advancements in anatomy and physiology had on ballet and ballet training? Q2 What are the origins of ballet principles such …
Strictly Ballroom: Examining How The Culture Of Collegiate Ballroom Dance Influences Body Image Perceptions, Rachel Neil
Strictly Ballroom: Examining How The Culture Of Collegiate Ballroom Dance Influences Body Image Perceptions, Rachel Neil
Master's Theses
The purpose of this study was to examine the influence that collegiate ballroom dance programs have on participants’ body image perception and self-esteem and to identify what sort of effect those perceptions have on performance satisfaction. In this project the researcher surveyed twenty-four students, ten males and fourteen females, who were presently involved in a collegiate ballroom dance program with a goal of identifying what sort of influence the culture of their ballroom dance programs had on each participant’s body image and self-esteem. The research instrument used in this study was an electronic survey that included yes or no questions, …
Educational Leadership Can Dance: A Deeper Look Into The Efficiency Behind Evaluations Of Dance Educators, Helen Brown
Educational Leadership Can Dance: A Deeper Look Into The Efficiency Behind Evaluations Of Dance Educators, Helen Brown
Master's Theses
The purpose of this study was to provide information on the issue of dance educator evaluation’s level of integrity, potential biases, and efficiency. Further, this study also acts as a review of current evaluation systems within public schools across the United States. The researcher received information about the evaluation systems from eleven dance educators in addition to how nine educational leaders evaluate their dance educators, along with one educational leader’s personal insight into their respective evaluation process. The research instruments utilized were online surveys and interviews. Both the surveys and interview responses were analyzed both quantitatively and qualitatively, depending on …
Exploring Dissociation As A Facilitator Of Suicide Risk Using Virtual Reality, Nicole Caulfield
Exploring Dissociation As A Facilitator Of Suicide Risk Using Virtual Reality, Nicole Caulfield
Master's Theses
Research shows that suicidal behavior is not a result of a single cause or single event, but instead is an interaction of facilitators. One potential facilitator that needs further exploration is dissociation. Dissociation has been consistently linked to suicidal behavior, and treatment for dissociative disorders seem to be associated with a reduction of suicidal ideation and suicide attempts. Prior theories have posited that dissociation increases the possibility of a suicidal act because of intensified disconnect from the body. However, these theories do not indicate whether dissociation is a facilitator of suicide risk by increasing suicidal ideation, attempt behaviors, and capability …
Hate Speech, Habitus, And Identity Signaling On 4chan’S Politically Incorrect Board, Jonathon Geiger
Hate Speech, Habitus, And Identity Signaling On 4chan’S Politically Incorrect Board, Jonathon Geiger
Master's Theses
Websites, such as 4chan, have provided a place for extremism and hate speech to flourish through anonymous discourse. One group that has been especially important to this growth has been the alt-right. The alt-right is a far-right white nationalist movement that is known for engaging in trolling, creating memes, and generating conspiracy theories. Past research has focused on the amounts of hate speech and characterizing content on the website. However, past studies have not looked at the experience of using the website through the combination of participant observation and content analysis. Here I show that the extensive use of hate …
Analysis Of Electroanatomic Mapping System Accuracy Using X-Ray Reconstruction Of Electrode Locations In A Porcine Animal Model, Hana Boudlali
Analysis Of Electroanatomic Mapping System Accuracy Using X-Ray Reconstruction Of Electrode Locations In A Porcine Animal Model, Hana Boudlali
Master's Theses
Fluoroscopy is considered the gold standard for locating catheters during cardiac electrophysiology (EP) procedures. However, fluoroscopy emits ionizing radiation which can lead to adverse health effects when exposed to in high doses (World Health Organization, 2016). Electroanatomic mapping (EAM) systems display the three-dimensional location of EP catheters and measure the local electrical activity of the heart. They can minimize a physician’s reliance on fluoroscopy and can help reduce radiation exposure during a case (Casella, 2011).
EAM systems are diagnostic medical devices that inform the placement of ablation therapy and must accurately locate catheters to be deemed safe. Test methods to …
Phantom Ocean, Real Impact: Natural Surf Sound Experiments Alter Foraging Activity And Habitat Use Across Taxa, Ryan N. Wardle
Phantom Ocean, Real Impact: Natural Surf Sound Experiments Alter Foraging Activity And Habitat Use Across Taxa, Ryan N. Wardle
Master's Theses
A growing body of research focuses on how background sounds shape and alter critical elements of animals’ lives, such as foraging behavior, habitat use, and ecological interactions (Bradbury & Vehrencamp, 2011; Barber et al., 2010; Kight & Swaddle, 2011; Shannon et al., 2016). Much of this research has centered on the effects of anthropogenic noise (Dominoni et al., 2020; Francis & Barber, 2013; Ortega, 2012; Swaddle et al., 2015), but recent studies have also revealed that natural sound sources can influence animal behavior (Davidson et al., 2017; Le et al., 2019). Natural sounds, such as crashing surf, can create conditions …
Improving Sustainable Fertilizer Practices For Pomegranate By Leaf Nutrient Concentration Evaluation And Fertilizer Trials, Minh Le
Master's Theses
Fruit tree leaf nutrient concentrations are commonly used to determine fertilizer rates, but information is limited regarding nutrient requirements, seasonal N uptake and removal rates, and soil N dynamics for pomegranate. Relationships between fertilizer rates, leaf nutrient concentrations, fruit yield and quality were examined in five mature, commercial California ‘Wonderful’ pomegranate orchards. Site 1 was observed for two growing seasons (2018-2019) and sites 2-5 were observed for one season (2018 or 2019). In 2018, 150, 300, or 450 g N/tree was applied at sites 1-3 in a single application at early fruit development or in two equal applications at early …
A Protocol For Achieving Adherent Cell Culture Within A Microfluidic Device, Tarra Danielle Sanders
A Protocol For Achieving Adherent Cell Culture Within A Microfluidic Device, Tarra Danielle Sanders
Master's Theses
The goal of this study is to design a protocol for the adherent cell culture within a novel microfluidic device. Microscale cell culture protocols were developed for loading cells using poly-L-lysine to enhance adherent cell culture of murine derived NIH 3T3 fibroblasts. This work sought to develop a method for adherent microculture by examining various sterilization, surface treatment, and seeding techniques. Using a vacuum suction loading technique, air plasma treatment and a poly-L-lysine surface treatment adherent cell culture was observed within the device. The work presented here is part of a collaborative effort that aims to develop protocols for the …
Understanding The Effects Of Long-Duration Spaceflight On Fracture Risk In The Human Femur Using Finite Element Analysis, Keyanna Brielle Henderson
Understanding The Effects Of Long-Duration Spaceflight On Fracture Risk In The Human Femur Using Finite Element Analysis, Keyanna Brielle Henderson
Master's Theses
Long-duration spaceflight has been shown to have significant, lasting effects on the bone strength of astronauts and to contribute to age-related complications later in life. The microgravity environment of space causes a decrease in daily mechanical loading, which signals a state of disuse to bone cells. This affects the bone remodeling process, which is responsible for maintaining bone mass, causing an increase in damage and a decrease in density. This leads to bone fragility and decreases overall strength, posing a risk for fracture. However, there is little information pertaining to the timeline of bone loss and subsequent fracture risk.
This …
Impact Of Soil Properties On Removal Of Emerging Contaminants From Wastewater Effluent During Soil Aquifer Treatment, Lauren N. Riley
Impact Of Soil Properties On Removal Of Emerging Contaminants From Wastewater Effluent During Soil Aquifer Treatment, Lauren N. Riley
Master's Theses
This study evaluates soil properties that impact the effectiveness of soil aquifer treatment (SAT) as a polishing step to the remove two classes of ECs from wastewater effluent: pharmaceuticals and personal care products (PPCPs), and engineering nanomaterials (ENMs). In recent years, it has been determined that elevated levels of emerging contaminants (ECs) are being released into the environment with wastewater effluent. ECs are proven to cause adverse environmental and health effects as a result of long-term exposure. It is important to evaluate sustainable solutions to improve the current methods of wastewater treatment to address these ECs.
Soil aquifer treatment (SAT) …
Eelgrass (Zostera Marina) Population Decline In Morro Bay, Ca: A Meta-Analysis Of Herbicide Application In San Luis Obispo County And Morro Bay Watershed, Tyler King Sinnott
Eelgrass (Zostera Marina) Population Decline In Morro Bay, Ca: A Meta-Analysis Of Herbicide Application In San Luis Obispo County And Morro Bay Watershed, Tyler King Sinnott
Master's Theses
The endemic eelgrass (Zostera marina) community of Morro Bay Estuary, located on the central coast of California, has experienced an estimated decline of 95% in occupied area (reduction of 344 acres to 20 acres) from 2008 to 2017 for reasons that are not yet definitively clear. One possible driver of degradation that has yet to be investigated is the role of herbicides from agricultural fields in the watershed that feeds into the estuary. Thus, the primary research goal of this project was to better understand temporal and spatial trends of herbicide use within the context of San Luis …
The Impact Of A Casve-Cq Enhanced Intervention On Group Career Counseling Outcomes, Kendall L. Klumpp
The Impact Of A Casve-Cq Enhanced Intervention On Group Career Counseling Outcomes, Kendall L. Klumpp
Master's Theses
This study aimed to investigate the effect of using the CASVE Cycle Questionnaire (CASVE-CQ) on career group intervention outcomes, specifically career decidedness, negative career thoughts, career decision-making difficulties, and career decision-making self-efficacy. Participants included 45 undergraduate students who receive scholarships from a student retention program which includes a career group intervention as a requirement to receive the scholarship. It was predicted that the use of the CASVE-CQ would result in greater increases in career decidedness and career decision-making self-efficacy, as well as greater decreases in negative career thoughts and career decision-making difficulties compared to those receiving the same intervention that …
My Child’S Keeper: Child Vulnerability And Quality Of Life On Parental Stress And Grit, Abigail Armstrong
My Child’S Keeper: Child Vulnerability And Quality Of Life On Parental Stress And Grit, Abigail Armstrong
Master's Theses
There is a reciprocal relationship between parenting stress and child distress that has been well documented (e.g., Rechenberg, Grey & Sadler, 2017). These effects generalize to physical outcomes such that higher maternal depression has been associated with poorer child health-related quality of life (HRQOL; Jaser, Whittemore, Ambrosino, Lindemann, & Grey, 2008). In the same way that parental distress has been shown to affect the child, parental perceptions of child vulnerability in children with chronic illness has also been associated with negative outcomes, including child depressive symptoms (Mullins et al., 2004), increased health care use (Spurrier et al., 2000), and increased …
Development And Use Of An Environmental Dna Tool To Monitor Recovery Of The Critically Endangered Smalltooth Sawfish, Pristis Pectinata, In The Northwest Atlantic, Ryan N. Lehman
Master's Theses
The Critically Endangered Smalltooth Sawfish, Pristis pectinata, was once common in the tropical and subtropical waters of the Atlantic Ocean; however, following global declines in range and abundance over the past century, individuals were restricted to the waters of south and southwest Florida (SWFL) by about the 1980’s. Recently, public encounter reports have emerged in historically occupied habitats in United States waters, suggesting individuals are present in, or re-occupying, these areas, although the status of P. pectinata outside of SWFL is not currently well understood. Targeted environmental DNA (eDNA) surveys were chosen to assess the occurrence of P …
Effects Of Infection Of The Protist Parasite, Dermomycoides Sp., In Dusky Gopher Frog Tadpoles, Jaime Smith
Effects Of Infection Of The Protist Parasite, Dermomycoides Sp., In Dusky Gopher Frog Tadpoles, Jaime Smith
Master's Theses
Infections of the protist parasite, Dermomycoides sp. are thought to have caused several years of low recruitment in the dusky gopher frog (Rana sevosa) populations. I evaluated the effects of density of the infective zoospores, host developmental stage, and tadpoles' ability to acquire resistance to Dermomycoides sp. on dusky gopher frog tadpoles. Tadpoles were exposed to zoospore densities of 0, 250, 500, and 750 zoospores/µL at Gosner stage 25, and we found no significant differences among treatments in tadpole mortality. In evaluating susceptibility by development stage, I exposed R. sevosa to 50 zoospores/µL as eggs, embryos, hatchlings, and …
Nutrition At Tipu: A Comparative Analysis Of Juvenile Health In Maya Populations, Sydnie A. Bianchi
Nutrition At Tipu: A Comparative Analysis Of Juvenile Health In Maya Populations, Sydnie A. Bianchi
Master's Theses
The site of Tipu in west central Belize provided a foothold for Spanish missionaries in the 17th century. The effects of contact on adults among the 550 burials recovered in the cemetery there have been well studied, but the children have received less attention. Therefore, this study examined juvenile health through four markers: Linear Enamel Hypoplasia (LEH), a non-specific marker of health disruptions; Porotic Hyperostosis (PH), an indicator of anemia; and Periostitis, an indicator of infection. Some 131 individuals were evaluated using criteria developed by Steckel, Sciulli, and Rose (2002). The results were compared to Late Classic Copán (Storey, …
Assessment Of Genetic Diversity In Largetooth Sawfish, Pristis Pristis, Populations Over The 20th Century, Ann Fearing
Assessment Of Genetic Diversity In Largetooth Sawfish, Pristis Pristis, Populations Over The 20th Century, Ann Fearing
Master's Theses
The Critically Endangered Largetooth Sawfish, Pristis pristis, experienced global declines in range and abundance over the past century and Australia is now their last stronghold. This research aimed to understand whether these declines have been accompanied by a reduction in levels of genetic diversity. Using P. pristis tissue samples sourced from natural history specimens, three fragments (616-bp, 386-bp, 141-bp) in the mitochondrial DNA (mtDNA) control region were PCR-amplified. At each fragment, significant genetic structure was found in P. pristis overall (ΦST=0.946, N=9; 0.813, N=54; 0.771, N=99). The Indo-West Pacific and Atlantic/Eastern Pacific each harbor genetically distinct lineages of …
Microplastic Abundance, Distribution And Impacts On Sargassum-Associated Juvenile Fishes In The Gulf Of Mexico, Olivia Lestrade
Microplastic Abundance, Distribution And Impacts On Sargassum-Associated Juvenile Fishes In The Gulf Of Mexico, Olivia Lestrade
Master's Theses
Microplastics are a concern in marine environments because they are highly durable, ubiquitous, and can be mistaken for food and ingested by small organisms. Pelagic Sargassum, an important habitat for larval and juvenile stages of many fish species, is found in large surface aggregations, and may provide complex structure in which microplastics become trapped. This could lead to greater risk of microplastic ingestion by fish early life stages associated with Sargassum habitats. To better understand the impacts of microplastics within Sargassum communities, this study examined 1) microplastic concentrations and ingestion by juvenile fishes associated with Sargassum; 2) the microbial …
Burned Out But Barely Begun: A Qualitative Study On Newer Clergy And Communication Surrounding Emotional Labor And Personal Well-Being In South Mississippi, Lauren Noll
Master's Theses
This study provides an overview of the concepts surrounding clergy burnout,
organizational culture, and emotional labor theory. Furthermore, it explains the need
for clearer understanding of clergy perceptions of their own personal
experiences with burnout and their emotional wellbeing in relation to their organizational environment and careers as clergy members. The methodology of qualitative interviews sought to understand the narratives and experiences of clergy members from their own words and worldviews rather than from a statistical basis or analysis.
This research found answers to key questions involving communication about burnout in the context of organizational culture and emotional labor, including …
Validation Of An Inertial-Measurement-Unit System For Calculating Hip And Knee Flexion Angles During Gait, Joonsun Park
Validation Of An Inertial-Measurement-Unit System For Calculating Hip And Knee Flexion Angles During Gait, Joonsun Park
Master's Theses
Technological advances regarding Inertial Measurements Units (IMUs) have positioned this type of sensor as an alternative for camera-based motion capture. This study introduces a new IMU based system (IMUsys) to measure hip and knee flexion angles. PURPOSE: To validate the use of a five-sensor IMUsys for the measurement of knee and hip flexion angles during gait in adults and pediatrics at two different time points. METHODS: Bilateral hip and knee flexion patterns (LH, RH, LK, and RK) of twenty-two healthy participants (12 adults and 10 pediatric) between the ages of 8 – 35 years were investigated. Participants …
A Comparison Of Two Protein Supplements On The Healing Of Stage Iii And Iv Pressure Injuries In Enterally Fed, Ventilator Dependent Long – Term Care Residents, Kalli Talaska
Master's Theses
The purpose of this study was to evaluate the change in stage III or IV pressure injury size of enterally fed, ventilator dependent, long-term care residents after receiving one of two protein supplements in addition to enteral feeding meeting 100% of calculated needs. The two protein supplements were Beneprotein™ (powder) and Pro T Gold™ (liquid). The injuries were evaluated for change in size at two weeks and four weeks post initiation of protein supplement. Sixty subjects were reviewed – 30 for each supplement. Subjects included 20 males (33%) and 40 females (67%). The analysis indicated for the total sample, a …
The Relationship Between Company, Manager, Group, And Individual-Level Variables And Affective Commitment, Varavit Chinnapong
The Relationship Between Company, Manager, Group, And Individual-Level Variables And Affective Commitment, Varavit Chinnapong
Master's Theses
Predicting employees' affective commitment to their organization continues to be of strong interest to researchers. Previous studies have examined the relationship between specific organizational levels (company, manager, group, individual) and affective commitment. However, there is a lack of research that has analyzed all four levels in one study. Therefore, the current study sought to evaluate the relationships between the four organizational levels and affective commitment. More specifically, the current study analyzed human resources practices as the company-level variables, transformational and transactional leadership as the manager-level variables, group cohesion as the group-level variable, and psychological safety at the individual level. The …
The Moderating Effect Of Leadership Adaptability On The Relationship Between Employee Adaptability And Job Performance, Justine Davis
The Moderating Effect Of Leadership Adaptability On The Relationship Between Employee Adaptability And Job Performance, Justine Davis
Master's Theses
The purpose of this study was to investigate the potential moderating effect of leadership adaptability on the relationship between employee adaptability and employee job performance. Previous research explored leadership adaptability as a mediator; however, there was a significant gap exploring leadership adaptability as a moderator. Participants were recruited via online social and personal networks. 125 participants completed a self-report survey consisting of items measuring employee adaptability, perceived manager adaptability and job performance. Results did not show perceived manager adaptability as a moderator of the relationship between employee adaptability and job performance. The results indicated that there were significant relationships between …
Lc-Ms/Ms Method Development For The Quantitation Of Methylmalonic Acid Using Aqueous Normal Phase Chromatography, Daniel Joseph Biocini
Lc-Ms/Ms Method Development For The Quantitation Of Methylmalonic Acid Using Aqueous Normal Phase Chromatography, Daniel Joseph Biocini
Master's Theses
The aim of the study was to develop a quantitative assay for methylmalonic acid (MMA), an important biomarker for clinical diagnosis of vitamin B12 (B12) deficiency. The techniques of liquid chromatography and tandem mass spectrometry (LC-MS/MS) are used for separation and quantitation of MMA, as well as its endogenous isomer succinic acid. The MS/MS method was developed using an infusion set-up and manual tuning experiments. Relevant transitions were detected for the two analytes and MMA-d3, then a preliminary MS/MS method was developed. The preliminary LC method was further optimized. Various gradients, mobile phases (MPs), and additive combinations were used across …
Using Kinetics And Small Angle X-Ray Scattering To Elucidate The Allosteric Regulation Of Sirt1, Christiane Cabreros
Using Kinetics And Small Angle X-Ray Scattering To Elucidate The Allosteric Regulation Of Sirt1, Christiane Cabreros
Master's Theses
SIRT1 is an NAD+ dependent deacetylase that has been implicated in many important cellular functions such as neurodegeneration and aging. SIRT1 has also been studied with resveratrol which was shown to modulate activity. While the mechanism of SIRT1 has been studied extensively, exact details are still not known, specifically the allosteric regulation by the N-terminal domain. We wanted to see if there is a correlation between the activity of SIRT1 and the distance of the N-terminal domain relative to the catalytic core. First we examined the kinetic parameters (kcat and KM) of SIRT1 with peptide substrates with and without resveratrol. …