Digital Commons Network^™

A Replication-Inducible Recombinant Vaccinia Virus System To Conditionally Transcribe The Entire Human Rhinovirus C Genome, Zhixin Jing

Master's Theses

No abstract provided.

Computational Design Of Ceramic Bone Scaffolds Fabricated Via Direct Ink Writing, Jeffrey Roberge

Master's Theses

Bone scaffold porosity and stiffness play a critical role in the success of critical-size bone defect rehabilitation. In this work, we present a computational procedure to design ceramic bone scaffolds to provide adequate mechanical support and foster bone healing. The scaffolds considered in our study consist of a lattice of curved rods fabricated via direct ink writing. We develop cellular solids models of the scaffold's effective elastic constants as functions of its geometric parameters, up to some unknown coefficients. To determine numeric values for these coefficients, we execute a computational design of experiments whereby effective elastic properties are obtained using …

Identifying Association Between Pedestrian Safety Interventions And Street Crossing Behavior Considering Demographics And Traffic Context, Franklin J. Caraballo

Master's Theses

Pedestrian fatalities are becoming a larger percentage of overall fatalities in the United States, therefore pedestrian safety research is essential for understanding and improving pedestrian safety. Pedestrian safety interventions are often used to educate and consequently improve pedestrian behavior. This study used pedestrian safety interventions to assess their effect on the respondents’ stated crossing behavior. Also, specific demographic data was used in this study to identify behavioral trends regarding street crossing behavior. The results show that pedestrian safety interventions are significantly associated with changes in pedestrian crossing behavior. The effect of the interventions was predominantly positive, since the respondents’ behavior …

Identification Of Agricultural Land Use In California Through Remote Sensing, Todd Allen Robinson

Master's Theses

Ground truthing actual crop types in an area can be expensive and time-consuming. The California Department of Water Resources attempts to ground truth land use in each county in California every five years. However, this is limited by budgetary constraints and often results in infrequent (more than every ten years) surveying of many counties. An accurate accounting of crops growing in a region is important for a variety of purposes including farm production estimates, groundwater and surface water modeling, evapotranspiration estimation, water planning, research applications, etc. Agricultural land use is continually changing due to development and environmental factors.

Currently, USDA …

Scaled Synthetic Aperture Rader Development, Jason Garvey Schray

Master's Theses

Several previous Cal Poly thesis projects involve synthetic aperture radar (SAR), automatic target recognition (ATR), and tracking. SAR data was either accessed from a publicly available database or generated using complex computer modeling software. The motivation for this dual thesis project is to design and construct a scaled SAR system to support Cal Poly radar projects. Ideally this is a low-cost, high resolution SAR architecture that produces raw range Doppler data for any desired target area. To that end, a scaled SAR system was successfully designed, built, and tested. The current SAR system, however, does not perform azimuthal compression and …

A Comparison Of Wavelet And Simplicity-Based Heart Sound And Murmur Segmentation Methods, Joshua David Korven

Master's Theses

Stethoscopes are the most commonly used medical devices for diagnosing heart conditions because they are inexpensive, noninvasive, and light enough to be carried around by a clinician. Auscultation with a stethoscope requires considerable skill and experience, but the introduction of digital stethoscopes allows for the automation of this task. Auscultation waveform segmentation, which is the process of determining the boundaries of heart sound and murmur segments, is the primary challenge in automating the diagnosis of various heart conditions. The purpose of this thesis is to improve the accuracy and efficiency of established techniques for detecting, segmenting, and classifying heart sounds …

Post-Liquefaction Residual Strength Assessment Of The Las Palmas, Chile Tailings Failure, Tristan Reyes Gebhart

Master's Theses

Assessment of post-liquefaction residual strength is needed for the development of empirically-based, predictive correlations for earthquake engineering design. Previous practice commonly assigned negligible strengths to liquefied materials for engineering analysis, producing overly-conservative designs. Increasingly available case history data, and improved analytical tools have allowed for more accurate and less overly-conservative estimation of soil residual strength, improving empirical predictive models. This study provides a new case history to the limited suite of (approximately 30) liquefaction failure case histories available for post-liquefaction in-situ strength predictive correlations.

This case history documents the Las Palmas gold mine tailings dam failure, resulting from seismic-induced liquefaction …

Analysis Of Machine Learning Classifier Performance In Adding Custom Gestures To The Leap Motion, Eric Yun

Master's Theses

The use of supervised machine learning to extend the capabilities and overall viability of motion sensing input devices has been an increasingly popular avenue of research since the release of the Leap Motion in 2013. The device's optical sensors are capable of recognizing and tracking key features of a user's hands and fingers, which can be obtained and manipulated through a robust API. This makes statistical classification ideal for tackling the otherwise laborious and error prone nature of adding new programmer-defined gestures to the set of recognized gestures.

Although a handful of studies have explored the effectiveness of machine learning …

A 3-D Multiplex Paper-Microfluidic Platform, Mitchell Patrick Young

Master's Theses

3-D paper-based microfluidic devices (micoPADs) are small and portable devices made out of paper that offer a promising platform for diagnostic applications outside of a laboratory. These devices are easy to use, low cost, require no power source, and capable of detecting multiple targets simultaneously. The work in this thesis demonstrated the ability of a 3-D paper-microfluidic platform to simultaneously detect 5 targets. Rubber cord stock was used in conjunction with an acrylic housing unit to apply pressure along the edge of the channel. The indirect pressure application was successful in promoting vertical fluid flow between layers. Average channel development …

Gender In 17th Century Southern New England, Megan K. Willison

Master's Theses

This thesis, written in the form of two broadly related articles, aims to address questions related to topics of gender, identity, cultural change and continuity, and the materiality of social institutions. Each article investigates how artifacts, as physical objects unintentionally or purposefully discarded, represent and reflect human behavior, societal ideologies, and cultural infrastructures. Using primary sources, archaeological evidence, and linguistic data, each article proposes that certain artifact classes are representative of larger societal ideals and cultural mores, such as gender systems and ways of defining one's gender identity. The first article studies these topics through the analysis of funerary remains …

An Empirical Study Of Problem-Based Learning Of English In China, Xinning Cui

Master's Theses

Abstract

The purpose of this study was to examine the impact of problem-based learning on 9^th grader Chinese students’ performance on writing, speaking and self-efficacy in learning English. Of particular interest to this study was the comparison of problem-based learning with the traditional Chinese learning method for improving students’ performance on English language writing and speaking, and in addition, students’ self-efficacy towards English learning. An empirical experiment was conducted in Qingdao No.2 high school in Shandong province, China. Both quantitative and qualitative methods were used. The findings show that students using the problem-based learning method tend to have stronger …

Examining Altered Neural Activation In Patients With Patellar Tendinopathy: A Preliminary Study, Steven Davi

Master's Theses

ABSTRACT

Examining altered neural activation in patients with patellar tendinopathy: a preliminary study

Davi SM, Lepley LK, Lepley AS, Denegar CR, Aerni G, DiStefano LJ: Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, CT.

CONTEXT: Patellar tendinopathy (PT) is a common injury that can affect 15-45% of all athletes, with nearly 50% of these athletes reporting no longer being able participate in sport due to the severity of the injury. One of the consequences of PT leading to physical inactivity is muscular weakness, particularly in the quadriceps, which may be attributed to arthrogenic muscle inhibition (AMI). OBJECTIVE: To …

Ecological Risks And Benefits From The Novel Crop Camelina Sativa (L.) Crantz (Camelina), Richard C. Rizzitello

Master's Theses

It is important to fully understand the ecological implications of introducing new crop species and genetic traits because of potential hazards such as changes in native plant populations or the establishment of aggressive weeds. Conversely, the introduction of new crops and traits could provide ecological benefits such as providing pollen and nectar forage for pollinators. Camelina sativa (camelina or false flax) is an oilseed crop that is being genetically engineered (GE) for the production of biofuel, bioplastics, and dietary supplements for humans and animals. Relatively little scientific information exists about camelina cultivation, reproductive biology, and ecology. The primary research goals …

Overtime Work Hours, Health Behaviors And Health Outcomes For Correctional Officers: An Examination Of Moderated Effects, Diana C. Tubbs

Master's Theses

Most of the existing research on corrections officers (COs) has focused on stress and burnout as well as the organizational factors that contribute to these outcomes. Recent studies have also revealed that COs are more likely to be obese and hypertensive than the general population. Studies not specific to corrections provide evidence that overtime hours are associated with poor employee health, and the present study aimed to address this general lack of research on the potential health impacts of overtime hours for COs. More specifically, this study investigated whether the effect of healthy behaviors on health and wellness outcomes changed, …

Chemosensory Function In Chronic Smokers: Findings From Nhanes 2011-2014 And An E-Cigarette Intervention, Sarah-Grace Glennon

Master's Theses

No abstract provided.

The Driver Of The Carbon Isotope Minima During The Last Deglaciation: A Weakened Biological Pump Or Enhanced Southern Ocean Circulation?, Melissa C. Cote

Master's Theses

The cause of the initial rise in atmospheric CO₂ during the last deglaciation remains unknown. Coincident with the rising atmospheric CO₂, the δ¹³C of atmospheric CO₂ decreased by ~0.3‰ during Heinrich Stadial 1 (HS1: 14.5-17.5 kyr BP), which requires the input of carbon from an isotopically light reservoir. The light carbon signal in the atmosphere occurred concurrently with the carbon isotope minimum, or a decrease in surface ocean δ¹³C of ~0.5‰, suggesting the two phenomena are related. The leading hypotheses explaining the δ¹³C minimum are (1) enhanced ventilation of ^{13 …}

The Self Relevance Of Stigma: The Impact Of Weight Stigma On Normal Weight Women's Health Cognitions, Paige Martinez

Master's Theses

Previous research has demonstrated that weight stigma is associated with negative health outcomes among women who are overweight; this effect has been shown in both experimental and longitudinal studies. However, normal weight women do not tend to experience negative health impacts from exposure to weight stigma. This study attempted to manipulate the self-relevance of weight stigma among 150 normal weight women, in order to test whether self-relevance of stigma has an impact on health cognitions. Limited support for this framework was found.

Individual Differences In Sensitivity To Morphological Structure In Words And Nonwords, Oliver M. Sawi

Master's Theses

Understanding visual word recognition has been a central goal of psycholinguistics from its early beginnings. Examination of the statistical properties of language has uncovered many aspects of words that facilitate recognition. In addition, evidence from both behavior and computational modeling suggests that individual differences in experience and the strength of connections in an individual’s reading network affect the sensitivity to these statistical properties in language. Morphology has special properties in this sense as morphologically related items have statistical regularities across both form and meaning. The current study examined whether individual differences in skill modulate sensitivity to morphological structure. Specifically, we …

Testing The Sea Level Hypothesis With New Records Along The Southern East Pacific Rise And Pacific Antarctic Ridge, Emily I. Seeley

Master's Theses

Melting glaciers may have indirectly affected submarine volcanism via changes in sea level. As sea level quickly drops, the rate of pressure change increases, resulting in decompression melting in the upper mantle, increasing magmatic flux. Given that hydrothermal activity at mid-ocean ridges is driven by near-axis magmatic heat, the concentration of hydrothermal proxies in ridge crest sediments (Fe, Mn, and As) can be used to infer long-term changes in hydrothermal plume activity. Using a series of well-dated sediment cores from the East Pacific Rise (EPR), we find glacial-interglacial variations in the concentrations of Fe, Mn, and As at multiple locations, …

Use Of Turkish Verbal Morphology By Children With Primary Language Impairment And Their Typically Developing Peers, Treysi Terziyan

Master's Theses

Language impairment in languages other than English has not been exhaustively studied. In the current study, we developed tasks that elicit productions of verbal morphemes from Turkish-speaking children. In the first part of the study we developed the tasks and piloted them on adults and school-aged children. In the second part of the study, we compared the performance of younger children with and without primary language impairment on the tasks we had developed. Our results suggested that adults and school-aged children were at or near ceiling on our tasks. Furthermore, the younger typically developing children performed near ceiling, whereas the …

A Physiologically Motivated Approach To The Classification Of Natural Sounds Using High Order Sound Statistics, Brian B. Bishop

Master's Theses

The ability of humans and animals to classify sounds into behaviorally relevant categories is an ongoing field of study in auditory neuroscience and psychophysics. We employed a physiologically motivated signal processing scheme to extract time-varying statistics from a large database of real sounds. Our hypothesis is that two sound statistics, intensity and contrast, will be sufficient to classify broad categories of sounds using a naïve Bayesian classifier. We seek to evaluate this hypothesis, determine to what extent these two time-varying statistics can be used to classify sounds and to evaluate the limitations of the technique. The sounds themselves were organized …

Risk-Based Approach To Assessment Of Advanced Technologies For Conceptual Design, Adipratnia Asmady

Master's Theses

The conceptual design phase of an aerospace system development program is typically characterized by short duration and relatively limited resources, yet design decisions are made that have critical implications on program risk. To address the more aggressive requirements, one of these decisions is the selection of advanced technologies. System developers need to assess advanced technologies early on, but are faced with uncertainties surrounding the potential net benefits. The concept introduced in this study is uncertainty characterization as a way to better understand the associated risk. A framework was developed to guide the interaction between the technology developer and the system …

Inducing Emotional Response In Interactive Media, Keenan M. Reimer

Master's Theses

Video games, and entertainment media have been developed for many years, and eliciting emotional experiences is an integral part of that process. Producing and editing game content in order to affect desired emotional experiences can be expensive and cumbersome to developers. This paper presents a study intended to show that such experiences can be affected with simple after-the-fact audio-visual effects. As subjects of the study, participants experience three different emotional states, fear, peace, and none, over three rounds and in three different game environments. They are given a simple narrative in each environment that directs them to gather various objects. …

Effects Of Fire On Soil Co₂ Efflux In A Mature Longleaf Pine Forest, Knox Lemee Flowers

Master's Theses

This study was conducted from 2012-2013 in a 96 year old longleaf pine at the Lake Thoreau Environmental Center located Lamar County, MS. Measurements of soil CO₂ efflux (i.e., soil respiration or SR) rates (µmol m^-2 sec^-1) were taken across 8 field plots (4 burned, 4 unburned) before and after a prescribed fire on that occurred in May, 2012. These measurements were taken over diurnal cycles using a LICOR LI-8100A automated soil gas flux system with long term chambers. SR rates and soil temperature measurements were collected during 3 sampling periods in 2012 and 1 sampling period …

The Effects Of 4-Nonylphenol On The Immune Response Of The Pacific Oyster, Crassostrea Gigas, Following Bacterial Infection (Vibrio Campbellii), Courtney Hart

Master's Theses

Endocrine disrupting chemicals (EDCs) are compounds that can interfere with hormone signaling pathways and are now recognized as pervasive in estuarine and marine waters. One prevalent EDC in California’s coastal waters is the xenoestrogen 4-nonylphenol (4-NP), which has been shown to impair reproduction, development, growth, and in some cases immune function of marine invertebrates. To further investigate effects of 4-NP on marine invertebrate immune function we measured total hemocyte counts (THC), relative transcript abundance of immune-relevant genes, and lysozyme activity in Pacific oysters (Crassostrea gigas) following bacterial infection. To quantify these effects we exposed oysters to dissolved phase …

Fluid Flow Characterization And In Silico Validation In A Rapid Prototyped Aortic Arch Model, Alexandra Mariel Knauer

Master's Theses

Transcatheter aortic heart valve replacement (TAVR) is a procedure to replace a failing aortic valve and is becoming the new standard of care for patients that are not candidates for open-heart surgery [2]. However, this minimally invasive technique has shown to cause ischemic brain lesions, or “silent infarcts”, in 90% of TAVR patients, which can increase the patient’s risk for stroke by two to four times in future years [3]. Claret Medical Inc., a medical device company, has developed a cerebral protection system that filters and captures embolic debris released during endovascular procedures, such as TAVR. This thesis utilized CT …

The Preservation And Protection Of Native Biodiversity In The Guadalupe Nipomo Dunes Complex, Lindsey M. Whitaker, Matthew Ritter, Scott J. Steinmaus, Jonathan Hall

Master's Theses

The Guadalupe Nipomo Dunes Complex (GNDC) is located within the California Floristic Province, a biodiversity hotspot characterized by high rates of endemism and exceptional loss of habitat. In 1980, the US Fish and Wildlife Service described the GNDC as, “the most unique and fragile ecosystem in the State of California,” and ranked it first on a list of 49 habitat areas needing state protection. It is the largest coastal dune area in California and it is one of the last remaining, relatively intact ecosystems of its type and size in the western United States. The growing recognition of species decline …

The Proteomic Response Of Gill Tissue In Tidally And Subtidally-Acclimated California Mussels, Mytilus Californianus, To Acute Emersion-Induced Anoxia, Aubrie N. Fowler, Lars Tomanek

Master's Theses

Intertidal mussels regularly experience emersion-induced anoxia, in contrast to normoxic conditions experienced during submersion. We therefore hypothesized that acclimation to a tidal rhythm, as opposed to a rhythm of constant submersion, preconditions the proteome of the California mussel, Mytilus californianus, to respond differently to emersion-induced anoxia. Following acclimation, mussels either continued to receive the acclimation conditions (control) or were exposed to 100% nitrogengas (anoxia) during aerial emersion. We collected gill tissue for subsequent analysis of protein abundance with 2D gel electrophoresis and protein identification with tandem mass spectrometry. Relative to subtidally-acclimated mussels, tidally-acclimated mussels showed a greater propensity to …

Characterization Of Etbe + Cl And Isooctane + Cl Combustion Products Using Synchrotron Photoionization, Rong Yao

Master's Theses

The low temperature (298 – 700 K) oxidation characterizations of a series of fuel additives (ETBE and isooctane) were studied at advanced light source in Lawrence Berkley National lab, using a multiplexed chemical kinetics photoionization mass spectrometer with tunable synchrotron radiation. Using Cl atoms as initiators in presence of oxygen, photoionization data were collected. Data analysis was performed via characterization of the reaction species photoionization spectra and kinetic traces, from which the products and also the intermediates were identified. Relevant reaction dynamics on potential energy surfaces were calculated, reaction enthalpies of each individual step were presented using the CBS-QB3 composite …

The Poet's Corpus: Memory And Monumentality In Wilfred Owen's "The Show", Charles Hunter Joplin

Master's Theses

Wilfred Owen is widely recognized to be the greatest English “trench poet” of the First World War. His posthumously published war poems sculpt a nightmarish vision of trench warfare, one which enables Western audiences to consider the suffering of the English soldiers and the brutality of modern warfare nearly a century after the armistice. However, critical readings of Owen’s canonized corpus, including “The Show” (1917, 1918), only focus on their hellish imagery. I will add to these readings by demonstrating that “The Show” is primarily concerned with the limitations of lyric poetry, the monumentality of poetic composition, and the difficulties …