Digital Commons Network^™

An Investigative Study Into The Relationship Of Bone Morphogenetic Protein Antagonist Expression And Osteocyte Density By Region And Quadrant, Scott C. Mosher

Master's Theses

The role of cytokines and cell behavior and viability with respect to bone remodeling and bone behavior is an exciting area of orthopedic research. The purpose of this study was to investigate the relationships between BMP antagonist expression and osteocyte density, lacunar densities and osteocyte viability in cortical bone. Samples of unloaded tibial bone obtained from six C57Bl/6 mice were immunohistochemically stained for gremlin and noggin expression and also underwent methyl green staining to determine osteocyte presence. Bone sections were divided into four quadrants (cranial, caudal, medial and lateral) and three regions (proximal, mid shaft and distal), followed by analysis …

Biomechanical Comparison Of Wire Circlage And Rigid Plate Fixation For Median Sternotomy Closure In Human Cadaver Specimens, Mark Steven Wong

Master's Theses

Background:

Over 700,000 patients per year undergo open-heart surgery. Healing complication rates can be up to 5% of patients who undergo this procedure, with a morbidity rate of 50% if mediastinitis supervenes. A secure and rigid fixation of surgically divided sternum is critical to avoid healing complications. The purpose of this study was to compare the yield load, construct stiffness, ultimate load, displacement at ultimate load, and post-yield behavior of three sternotomy closure methods (Peristernal wires or Sternalock titanium plates) when stressed in each of three directions: lateral distraction, rostro-caudal (longitudinal) shear distraction, and anterior-posterior (transverse) shear in a cadaveric …

Consumers And Benefits Of Genetically Modified Vegetables, Megan Carter Judge

Master's Theses

With the adoption of biotechnology in many agricultural products with first-generation biotechnology traits such as increased pest resistance, greater herbicide resistance, and increased yields the growers have accepted them. The next wave of biotech crops have second-generation traits, such as improved nutrient content, extended shelf life, reduced pesticide and herbicide application (a consumer demanded trait), and better taste. Will these consumer benefits offset any concern that the consumer has regarding biotechnology? What are those benefits and how should the information be communicated to the consumer?

Three focus groups give insight to the proposed questions. The focus groups were done in …

Near Real-Time Exercise Machine Power Statistics Reporting, Brendan C. Asche

Master's Theses

Cal Poly’s Recreation Center expansion project provides an opportunity to implement Energy Harvesting From Exercise Machines (EHFEM). Part of this implementation is a system that reports the exercise machines’ energy production. Although products capable of reporting exercise machine energy harvesting statistics exist, they have limited capabilities. This thesis project defends a system capable of reporting exercise machine power statistics in near real-time.

The system consists of display, database, and power measurement modules. The display module presents statistics in an interactive, graphical, and widely-accessible way. The database module provides an efficient way of organizing and accessing stored statistics. Multiple power measurement …

Exploring The Relationship Of The Closeness Of A Genetic Algorithm's Chromosome Encoding To Its Problem Space, Kevin Mccullough

Master's Theses

For historical reasons, implementers of genetic algorithms often use a haploid binary primitive type for chromosome encoding. I will demonstrate that one can reduce development effort and achieve higher fitness by designing a genetic algorithm with an encoding scheme that closely matches the problem space. I will show that implicit parallelism does not result in binary encoded chromosomes obtaining higher fitness scores than other encodings. I will also show that Hamming distances should be understood as part of the relationship between the closeness of an encoding to the problem instead of assuming they should always be held constant. Closeness to …

Temperature Affects Adhesion Of The Acorn Barnacle (Balanus Amphitrite), Laurel A. Johnston

Master's Theses

Biofouling is the accumulation of sessile marine organisms, such as algae, tube worms and barnacles on man-made substrata and has negative economic and ecological implications. Ship hulls are readily fouled, which significantly increases drag while decreasing ship fuel efficiency when moving through water. Fouled hulls have also become important vectors of invasive species. These problems are minimized when hulls are painted with a toxic anti-fouling or non-toxic foul-release coating. Due to recent restrictions of anti-fouling paint use, research and development of non-toxic alternatives has increased.

Novel hull coating efficiency is often quantified by the critical removal stress value of barnacles …

St. Jude Medical: St Monitoring, Anna Marie Kinney

Master's Theses

Myocardial infarction is the leading cause of death in the western world. Time is critical when treating patients with myocardial infarction. The major problem is that many patients who are symptomatic wait too long before seeking medical attention, and some patients have no symptoms at all. In order to improve patient outcome there needs to be a better way to diagnose myocardial infarction. One solution is the continuous monitoring of the ST-Segment of the intrinsic ventricular beat morphology, called the QRS complex. There have been many studies that show that there are detectable shifts of the ST-Segment during coronary occlusion. …

Autonomous Satellite Operations For Cubesat Satellites, Jason Lionel Anderson

Master's Theses

In the world of educational satellites, student teams manually conduct operations daily, sending commands and collecting downlinked data. Educational satellites typically travel in a Low Earth Orbit allowing line of sight communication for approximately thirty minutes each day. This is manageable for student teams as the required manpower is minimal. The international Global Educational Network for Satellite Operations (GENSO), however, promises satellite contact upwards of sixteen hours per day by connecting earth stations all over the world through the Internet. This dramatic increase in satellite communication time is unreasonable for student teams to conduct manual operations and alternatives must be …

Developing A Source Water Protection Plan For Boron In The San Luis Obispo County Water Supply, Jenny Macartney

Master's Theses

The goal of this project is to design a feasible way to develop a protection plan for boron in the surface waters and groundwater of San Luis Obispo County. Boron is a micronutrient needed by all plants and animals but the threshold for toxicity in plants is narrow. As the need for water increases and the production of wastewater and irrigation water infiltrates the soil and waters of the County, an understanding of background soil and water concentrations, as well as anthropogenically produced sources of boron must be quantified and mapped so that intelligent planning decisions can be made.

Many …

Time-Temperature Curing Relationship Of An Adhesive Binder With Rice Straw, Kevin Ka-Wan Ng

Master's Theses

Rice straw is a global and proliferate agricultural waste whose production grossly outstrips viable uses. Current disposal methods are not sustainable, and more convenient methods – such as incineration – exude poor environmental stewardship. Although the direct use of straw bales in building construction presents a practical and sustainable alternative, engineering challenges associated with using it prevent its wide adoption. The Stak Block – a composite formed from compressed rice straw and a heat-cured adhesive – may overcome challenges associated with straw bale building. However, the times and temperatures needed to cure the binder with straw are not well understood. …

The Presence Of Micropterus Salmoides (Largemouth Bass) Influences The Populations Of Rana Draytonii (California Red-Legged Frog) And Pseudacris Regilla (Pacific Treefrog) In Two Ponds In Santa Barbara County, California, Kenneth Lee Gilliland

Master's Theses

Alien fish have been implicated in the decline of Rana draytonii (California red-legged frog) and Pseudacris regilla (Pacific treefrog) populations. Micropterus salmoides (largemouth bass) is a common sport fish that has been introduced into the sympatric range of these two anuran species; however, no studies have investigated the individual influence that this alien fish has on these two species. I conducted M. salmoides control or eradication experiments during a four year study in two ponds within the Transverse Mountain Range of Santa Barbara County, California. Changes in the densities of all life stages of R. draytonii and P. regilla were …

An Investigation Of Humeral Stress Fractures In Racing Thoroughbreds Using A 3d Finite Element Model In Conjunction With A Bone Remodeling Algorithm, Ryan James Moore

Master's Theses

The humerus of a racing horse Thoroughbred is highly susceptible to stress fractures at a characteristic location as a result of cyclic loading. The propensity of a Thoroughbred to exhibit humeral fracture has made equines useful models in the epidemiology of stress fractures. In this study, a racing Thoroughbred humerus was simulated during training using a 3D finite element model in conjunction with a bone remodeling algorithm. Nine muscle forces and two contact forces were applied to the 3-dimensional finite element model, which contains four separate load cases representing fore-stance, mid-stance, aft-stance, and standing. Four different training programs were incorporated …

Autumn Garden, Les Brady

Master's Theses

Autumn Garden is a novel using a semi-omniscient third-person narrator who conveys the perspectives of ten-year-old Nick Lucera, his mother, Mary, and father, Tony. The story challenges conventional beliefs of mortality as Nick confronts the greatest loss of his young life, his mother's impending death. The novel is set in 1970's coastal California.

Two characters influence how Nick processes events in his life: seventeen-year-old neighbor, Brian, an evangelical Christian, and Sal Amato, an acquaintance of Nick's parents, whose insights range from the curious to the fantastic. Brian's friendship is a refuge for Nick, who suffers regularly from the bullying inflicted …

Phenotypical And Functional Analysis Of Peripheral T Cells In Foxn1 Transgenic Mice: Effects Of Aging, Paulette Krishack

Master's Theses

The thymus is the primary organ for the development and production of TCRαβ naive T cells. However, with increasing age thymic involution occurs, causing a decline in the output of naïve T cells. The decline in naïve T cell production results in a contraction in the peripheral naïve and expansion of the memory T cell pools. Not only are the production and compositions of peripheral T cells altered with age, T cell functions such as T cell proliferation and production of cytokines required for cell proliferation are also declined. Currently, it is not known if restoring the decline in the …

A Framing Study Of Media Coverage On Climate Change From 1989 To 2009, Marie Mccann

Master's Theses

This thesis examined how climate change has been framed in four major news magazines--Maclean's, Newsweek, The Economist, and U.S. News and World Report--over the past 20 years. We looked at a number of framing elements, including primary frames, depth of coverage, framing the science, sources of information, section placement, and verbiage. A content analysis of 476 articles was performed. Articles included in the sample appeared in one of the four news magazines during the years 1989, 1993, 1997, 2001, 2005, and 2009 and included at least one sentence devoted to climate change. We found that the most predominant …

Interspecific Variation In Morphology And Swimming Performance Within Surfperches (Embiotocidae) From California, Benjamin Michael Perlman

Master's Theses

Surfperches are marine fishes that occupy nearshore habitats along the California coast. Morphology was analyzed to determine if there were differences among 19 preserved species. Principal components analysis (PCA) was used to reduce the dimensionality of the data. Morphological differences occurred among the 19 species. ANOVA revealed a habitat effect on PC2, which described the angle of attachment of the pectoral fin. Pearson correlation revealed that genetic relatedness decreased with increasing morphological differences on PC1, which described aspect ratio and body ratio. Based on PC2, four species were selected to conduct experiments on their swimming performance. U_crit and fin …

The Effects Of Bordetella Pertussis On Dendritic Cell Imprinting Of Cd4+ T Cells, Sana Waheed

Master's Theses

Bordetella pertussis is an aerobic gram-negative bacterial pathogen that causes the human respiratory disease whooping cough. Despite widespread vaccination, whooping cough is reemerging due to decreased vaccine efficacy. One of the hallmarks of infection is lymphocytosis, which is induced by the pertussis toxin. Lymphocytes such as CD4+ T cells navigate to infected tissues through surface-trafficking molecules, which are imprinted during their interaction with tissue-associated dendritic cells. We hypothesized that the pertussis toxin affects the imprinting process resulting in altered expression of trafficking molecules on CD4+ T cells. We tested this hypothesis using a mouse model of infection. Imprinting levels on …

Host-Parasite Ecology And Description Of The Louse Fly, Allobosca Crassipes, From Madagascar, Stanley Edmondson Vaughn

Master's Theses

The louse fly, Allobosca crassipes (Diptera: Hippoboscidae), is an obligate ectoparasite exclusive to lemurs in Madagascar. Research in Ranomafana National Park (RNP) in southeastern Madagascar has resulted in the identification of a new association of this fly with the black and white ruffed lemur, Varecia variegata variegata, and a confirmed association with Milne-Edwards' sifaka, Propithecus edwardsi. Previous descriptions of A. crassipes were based on only a few specimens, and the type specimen is presumed destroyed. The specimens of A. crassipes collected by SJSU in 2000-2001 provide the largest collection available for the purpose of describing this species.

Habitat …

Implementation Of Risk Management In The Medical Device Industry, Rachelo Dumbrique

Master's Theses

This study looks at the implementation and effectiveness of risk management (RM) activities in the medical device industry. An online survey was distributed to medical device professionals who were asked to identify RM-related activities performed during the device life cycle. RM activities and techniques included Establishing Risk Acceptance Criteria, Hazard Identification, Human Factors/Usability, Fault Tree Analysis (FTA), Design Failure Mode and Effects Analysis (DFMEA), Process Failure Mode and Effects Analysis (PFMEA), Hazard and Operability Study (HAZOP), Hazard Analysis and Critical Control Point (HACCP), Risk Benefit Analysis, and Risk Assessment of Customer Complaint. Devices were identified by type (therapeutic, surgical/clinical tools, …

Riparian Brush Rabbit Habitat Requirements In Caswell Memorial State Park, Clinton Robert Elsholz

Master's Theses

With the rapid growth of agricultural and urban development in California's Central Valley in the 20th and 21st centuries, many habitats, including riparian forests, have been drastically altered. Along with these habitats, species that are dependent on them have also been fragmented and their long-term survival threatened. The riparian brush rabbit (Sylvilagus bachmani riparius) is one such species that has experienced profound population contraction over the past century. This research was conducted at Caswell Memorial State Park ("the Park"), located in Ripon, California, which is the largest remaining habitat fragment within the rabbit's historical range. One objective of this research …

Marketing Latin Alternative Music Through Social Networking Sites, Vanessa Ursala Garcia

Master's Theses

This thesis examined the marketing strategies for Latin alternative music used on MySpace, Facebook, and Al Borde (On the Edge). This study found that the understanding of the target demographic was important for implementing successful marketing strategies to niche audiences. Marketing Latin alternative music has not been successful at a mainstream level; therefore, marketers have targeted niche communities on social networking sites. The most dominant strategy used involved the status update feature on Facebook. It allowed musicians and marketers to communicate information and media to a large network of individuals across the country. Three other major strategies included event invitations, …

The Art Of Camille Rose Garcia: An Existential Fairy Tale, Jennifer De La Cruz

Master's Theses

Camille Rose Garcia is part of a contemporary underground art movement known as Pop Surrealism. An apparent dream-like and unexpected nature borrows from the oeuvre of Surrealism, while an allusion to the familiar and popular denotes similarities to the comic culture of the 1930s and Pop Art of the 1960s. Garcia's paintings are laced with the personal remnants of childhood memories that recall frequent trips to Disneyland and visits to her grandparent's cabin tucked away in the redwood forests of Northern California. Her artwork, a haunting recipe of sweet and sour, beautiful and grotesque, ominous and nostalgic, travels through Los …

Ecology Of Foothill Yellow-Legged Frogs In Upper Coyote Creek, Santa Clara County, Ca, Thomas Earl Gonsolin

Master's Theses

Visual encounter surveys, mark-recapture technique, and telemetry were used investigate breeding, movement, growth, habitat preferences, and predators of foothill yellow-legged frogs on Coyote Creek in Santa Clara County, California, from March 2004 to March 2006. The main stem and tributaries were intermittent in summer in all three years. Thermal conditions for breeding initiation were alike during 2004, 2005, and 2006. Breeding occurred in the main stem on descending limbs of the hydrograph. No breeding occurred in the middle main stem reach, which is ephemeral. Breeding occurred at less than an order of magnitude greater than base flows. Typically, larger females …

Finding Duplication Events Using Genomevectorizer, Elena Kochetkova

Master's Theses

GenomeVectorizer is a software application designed to extend the functionality of GenomePixelizer, a genome-visualization tool that was developed for the Department of Plant Pathology at University of California, Davis, in 2002. GenomeVectorizer was written using XML, XSLT, and SVG technologies combined with JavaScript scripting to provide the level of flexibility, dynamism, and interactivity not supported by the TCL/TK written application (GenomePixelizer). This new visualization tool was tested with available data from the Arabidopsis NBS-LRR study, and its output was compared to the output of GenomePixelizer. The relationships drawn at the same identity value were identical.

GenomeVectorizer was successfully applied to …

Native Americans In The San Francisco Bay Area: Patterns In Ancient Teeth, Palimpsests Of Behavior, Dave Grant

Master's Theses

NATIVE AMERICANS IN THE SAN FRANCISCO BAY AREA:

PATTERNS IN ANCIENT TEETH; PALIMPSESTS OF BEHAVIOR

by Dave Grant

In analyzing burial populations from seven sites in the Santa Clara Valley, patterns on teeth were found that did not conform to the flat normative wear explanation. This study attempts to expand upon the seminal work of Molnar (1968), Hinton (1981), and Keiser (2001a, 2001b) and to propose a definitional refinement of wear patterns found on teeth from populations in Central California. Flat normative wear was present. In addition, four additional distinct wear patterns were found. Wear patterns include slants and scoops …

Absence Of Keratin 8 Is Associated With Marked Colon Mast Cell Infiltration, Diana El Bezri Nasser

Master's Theses

Patients with inflammatory bowel disease (IBD) have increased numbers of numbers of intestinal mast cells (MCs). Chymases and tryptases are mast-cell-specific proteases (MCPs) that are reliable indicators of MC degranulation. The role of MCs in the pathophysiology of IBD is poorly understood, and it is unclear whether MCs play a role in patients or in experimental models of IBD. Furthermore, MCs have been characterized only in chemically induced models of colitis. In this study, we characterize MCs in inflamed colons of keratin 8 knock-out mice (K8-/-), a spontaneous model of colitis with primarily an epithelial cell defect. We used histologic, …

Reproductive Den Habitat Characterization Of American Badgers (Taxidea Taxus) In Central California, Katrina Louise Huck

Master's Theses

The American badger (Taxidea taxus) is a species of special concern in California, and, as such, conservation measures are necessary. The goal of this study was to identify potential reproductive den habitat characteristics in order to more accurately predict critical reproductive habitat in central California grasslands. A paired study design was used to examine differences between reproductive and non-reproductive sites, and logistical regression was used to analyze the variables and produce two predictive models, one with biotic factors and one with abiotic factors. Badgers in central Californian grasslands appear to rely on both biotic and abiotic factors when …

Functionalized Silica Nanostructures For Biosensing Applications, Hector Nuno

Master's Theses

This work covers both two dimensional (2D) and three dimensional (3D) silica-based nanostructures for use in biomedical sensing applications. The first section of this study discusses the formation of 2D nanostructured surface plasmon resonance (SPR)-based biosensor substrates. The surface of these biosensors was nanostructured by adding sacrificial star polymers or block copolymers to a silicate precursor solution. Subsequent vitrification resulted in two distinct morphological patterns: random and ordered porosity. Amino groups on the surface of the biosensors enabled the installation of analyte receptors and antifouling agents such as oligo (ethylene oxide).

The second section discusses the development of 3D core-shell …

String Quartet No. 1, Jeffrey Scott Perry

Master's Theses

String Quartet No. 1, by Jeffrey Scott Perry, is absolute music. It uses unconventional techniques that challenge the interpretations of performers and listeners. Performers treat tempos and phrasing flexibly that yields a different version of the piece with each performance. The structure is Rounded Binary, but is manipulated to be purposefully obscure until the last measures of the piece. This is accomplished by incorporating ideas of motivic development into the overall form. The first four motifs are the source of all subsequent material. Therefore, motivic development is vital to the construction of the piece and becomes a unifying factor between …

Kinna-Uganda: A Review Of Uganda's National Cinema, Kristin Alexandra Rasmussen

Master's Theses

Kinna-Uganda (K-U) is a form of cinema that has emerged in Uganda following decades of the totalitarian political regime of Idi Amin, which in turn followed almost a century of colonial rule. The concept of national cinema is evaluated in this thesis as a tool for analysis of K-U. The national cinema concept is compared with four other models -- regional, continental, Pan-African, and transnational -- that can also be used to analyze and deconstruct films and the academic space within which they reside. This study examines Uganda's pre-colonial, colonial, and post-colonial times and their impact on the production of …