Digital Commons Network^™

The Effect Of Weighted Body Armor On Close Combat Reaction Time And Core Muscle Activation 2016, Christopher Banta

Master's Theses

The purpose of this study was to measure the choice reaction time and myoelectric activity of the right and left rectus abdominus, and right and left external obliques required to initiate movement in response to a visual stimulus that signaled performance of four different closecombat movements (left or right cross and left or right dodge). Reaction time and myoelectric activity were then compared with performing the movements in response to the visual stimulus while wearing a weighted vest that simulated wearing tactical body armor. Myoelectric activity was measured as the average root mean square (RMS) of the surface electromyography (sEMG) …

Diagnoses By Gender: The Consequences Of Treatment Of The Mentally Ill In Virginia Woolf's The Waves And Mrs. Dalloway 2016, Erika Nichole Jackson

Master's Theses

“Insanity is purely a disease of the brain…The physician is now the responsible guardian of the lunatic, and must ever remain so.” Sir John Charles Bucknill (1897)

Mental illness has consistently been and continues to be a subject that is viewed as taboo by society, especially when it comes to diagnosing a patient. Instead of acknowledging a person’s actions, thoughts, and words, society continually disregards mental illness as something that is negative and to be feared. The fact that this area of medicine can be difficult and distressing makes it all the more important to continue research. It is true …

"Do Not Fashion The Other": Representing Contemporary Haudenosaunee Literature 2016, Michael Patrick Brewster

Master's Theses

Historically, the issue of representation in postcolonial studies is one of some contention. While scholarship might recognize the necessity for highlighting the plights and struggles attendant to postcolonial societies, the primary literature being studied is most often written by natives of those societies themselves. This gap is especially evident with Indigenous cultures, because there are relatively few Indigenous scholars working in the academy. We are at the point now when we have a multiplicity (but not a plurality) of Indigenous voices writing literature (poetry, memoir, fiction, film, etc.) and academic criticism. However, there is value in non-Natives reading and writing …

'The Letter Killeth': The Obscurity Of Language And Communication In Thomas Hardy's Jude The Obscure 2016, Victoria T. Corning

Master's Theses

While the epistolary novel is a genre closely associated with 18th century England, 19th century Victorian literature also incorporates letter writing as a significant form of communication. Written messages convey what can often not be said out loud, as it is easier to hide behind a pen and paper, write in solitude, and be absent when the letter is read by the recipient. Impulsive and emotional thoughts and feelings can be written down immediately and then later edited, which makes writing an unstable form of communication. Is the author conveying true feelings or concealing true feelings? Layering multiple modes of …

A Study Of Osteocyte Apoptosis In Mechanically Loaded And Unloaded Murine Tibiae, Josiah Elihu Kessler

Master's Theses

Previous research has provided evidence in support of apoptotic osteocytes playing a role in the bone remodeling process. In this study, we examined the regional and quadrantal variations of apoptotic and viable osteocytes in cyclically loaded and unloaded samples. Left tibias of C57 Black 6 Taconic mice (C57Bl/6) were cyclically loaded for either 2 weeks or 5 weeks, with the right tibias being used as controls. After loading, tibias were resected, processed, and then stained using either a TUNEL stain, to show apoptotic osteocytes, or a 2.0% methyl green solution, to reveal viable cells. Cross-sectional images from each tibia were …

Age, Growth, Reproduction, And Diet Of The Finetooth Shark, Carcharhinus Isodon, In The Northern Gulf Of Mexico, Jeremy Michael Higgs

Master's Theses

The current study examined life history parameters of the finetooth shark, Carcharhinus isodon, in the northern Gulf of Mexico (nGOM) to provide an accurate description of the species’ reproductive biology, age, growth and diet composition. A total of 1,489 finetooth sharks (830 female; 659 male) were collected from coastal waters of the nGOM between Apalachicola Bay, Florida (29.873° N and 84.514° W) and East Bay, Louisiana (28.959° N and 89.279° W) from June 2006 through October 2013. Peak reproductive development occurred during May/June for both males and females, which was followed by mating and an 11-12 month gestation period. …

Pre- And Post-Partum Whistle Production Of A Bottlenose Dolphin (Tursiops Truncatus) Mother-Calf Dyad, Audra Elizabeth Ames

Master's Theses

Whistle use pre- and post-partum in an Atlantic bottlenose dolphin (Tursiops truncatus) mother-calf dyad has rarely been studied. The current study is the first to investigate signature whistle production by the mother pre- and post-partum, as well as whistle use by other members of the social group during calf development, and how exposure to these whistles may affect the calf’s vocal repertoire. Findings showed that the mother increased her rates both pre- and post-delivery, while other group members produced their whistles at decreased rates until the calf’s second week of life. After the calf’s second week, whistle rates of …

Social Interactions Among Two Males In A Captive Group Of Rough-Toothed Dolphins (Steno Bredanesis), Pepper Reid Hanna

Master's Theses

There is relatively little known about the social behavior of rough-toothed dolphins (Steno bredanensis) particularly in comparison to information on the Atlantic bottlenose dolphin, (Tursiops truncates). The purpose of the current study is to describe the social behavior of two juvenile male rough-toothed dolphins housed at Gulf World Marine Park in Panama City Beach, FL. Rates of affiliative social behaviors were greater between the two males within this group compared to the other pairs of dolphins. The males exhibited a high rate of association, calculated using the half-weight index. Following aggressive behavior within the overall group, the …

Optimization Of Rfid System Coverage In A Manufacturing Environment, Scott D. Malatesta

Master's Theses

This paper compiles existing ideas, theories, and experiments across multiple disciplines to provide guidance for a company looking to implement an optimal RFID system in their production facility. The desire is to maximize the information received by the system while minimizing the cost. Four potential layouts of RFID antennas, two with overlapping antenna coverage and two with non-overlapping layouts, are first analyzed to understand the special coverage and the number of antennas required. The value of information is then quantified to determine whether higher coverage layouts are worth the additional costs associated with the higher number of antennas required. It …

Crops Or Crafts? Changes In Land Use In The Imbabura Valley Of Ecuador, Christopher Richard Hair

Master's Theses

In rural societies where urbanization and modernization are contributing to rapid growth, changes in land use can both reflect and bring about broader changes within a community. This study seeks to investigate changes in land use in the Imbabura valley of Ecuador from the perspective of the local inhabitants. To accomplish this, three data collection techniques were employed: repeat photography, ethnographic interviews, and archival research. Repeat photography involves re-photographing historic photographs from the original site. A combination of 35 historic photographs taken in the 1950s were re-photographed during the summer of 2015. The resulting repeat photo pairs were used in …

Geometric Energies For Haptic Assembly, Morad Behandish

Master's Theses

Haptic-assisted virtual assembly and prototyping has seen significant attention over the past two decades. However, in spite of the appealing prospects, the adoption has been slower than expected. Putting hardware limitations aside, the main roadblocks faced in software development can be traced to the lack of effective and efficient computational models. Such models must 1) accommodate the inherent geometric complexities faced when assembling objects of arbitrary shape; and 2) conform to the computation time limitation imposed by the frame rate requirements---namely, 1 kHz for haptic feedback compared to the more manageable 30-60 Hz for graphic rendering. The fulfillment of these …

Predicting Changes To Source Code, Justin James Roll

Master's Theses

Organizations typically use issue tracking systems (ITS) such as Jira to plan software releases and assign requirements to developers. Organizations typically also use source control management (SCM) repositories such as Git to track historical changes to a code-base. These ITS and SCM repositories contain valuable data that remains largely untapped. As developers churn through an organization, it becomes expensive for developers to spend time determining which software artifact must be modified to implement a requirement. In this work we created, developed, tested and evaluated a tool called Class Change Predictor, otherwise known as CCP, for predicting which class will implement …

Effect Of Reduced Sodium Cheese On The Growth Of Pathogenic Bacteria And Inactivation Of Listeria Innocua Using Supercritical Fluid Extraction With Co2, Suyapa Padilla Antunez

Master's Theses

Listeria monocytogenes continues to challenge the dairy industry in causing post-process contamination of cheeses. To reduce risk of contamination, it is crucial to understand the growth and survival of pathogenic bacteria in cheese products and to develop post-process mitigation strategies. This study evaluated the fate of pathogens in reduced and regular sodium Mozzarella cheese, and the potential of Supercritical Fluid Extraction with CO₂ (SFE) to reduce Listeria innocua on Mozzarella and Queso Fresco. The survival of L. monocytogenes, Salmonella, and E.coli O157:H7 (2-3 log CFU/g) in reduced sodium Mozzarella (1.62%), compared to regular sodium Mozzarella cheese (2.15%) …

Design And Validation Of A Fall Detection Application For Ios, Connor Lewis Mosley

Master's Theses

Despite significant preventative efforts, falls continue to be a major source of morbidity and mortality among the elderly. Additionally, the fear of falling can be a major obstacle to independent living for otherwise self-sufficient individuals. This fear is significantly heightened in individuals who have sustained a fall and often results in self-imposed restrictions on mobility and exercise, causing weakening in these individuals and further exacerbating the danger. Much time has been spent developing alert systems in an attempt to mitigate these problems. Unfortunately these systems typically involve dedicated monitoring centers and therefore often come with substantial upfront and recurring costs. …

Investigation Of A Ubiquitous Spore Surface Protein, Justyna Kordzikowska

Master's Theses

All bacterial spores are comprised of concentric shells. All spores are encased in a layer called the coat. Some spores have an additional layer outside of the coat called the exosporium. Presumably, this morphological variation is an adaptation to variation in the environments in which these species can be found. However, spores from species with and without exosporia can often be found in the same niche. We hypothesize, therefore, that spores with and without exosporia share a common surface protein. Bacillus anthracis possess a well characterized surface protein called BclA. A BclA homologue is also present on the surface of …

The Relationship Of The Old Covenant To The Everlasting Covenant, Ashwani Kumar

Master's Theses

Problem

The old covenant is often understood to be contrary to the new covenant. A distinction is made by such claims as the following: the old covenant represents the Old Testament, and new covenant represents the New Testament. The old covenant was made with only Israelites while the new covenant is made with the Church. The old covenant was based on works, and the new covenant is based on grace and is better than the old.

Purpose

The goal of this study is to present evidence that the new covenant was not established because it was different in the content …

Land-Use And Algal Species Influence Bacterial Community Composition And Activity In Streams, Miguel Rojas

Master's Theses

Microbial biofilms can be found on virtually all submerged surfaces in aquatic habitats, including rivers and streams. Biofilms are complex, taxonomically diverse communities of microorganisms (including algae and bacteria) that colonize solid surfaces and support a wide range of metabolic activities. Biofilms are critical components of river and stream ecosystems because they are key drivers of nutrient cycling processes (including nitrogen cycling) and because they serve as an important food source for higher trophic levels. Biofilms in urban streams are subject to a number of anthropogenic stressors, but research on the ecology of urban biofilms and their response to stressors …

Adams As Potential Regulators Of Stem Cell Quiescence In The Olfactory Epithelium, Elaine Elizabeth Orendorff

Master's Theses

I demonstrate that a member of the protein family A Disintegrin and Metalloprotease (ADAM), ADAM23, is expressed in the olfactory epithelium (OE) and may inhibit neural progenitor cell (NPC) proliferation. I generated a list of ten gene candidates and selected ADAM23 for further study, based on its conserved protein structure and accumulating evidence for its role in cell cycle progression of proliferative cells. I next determined ADAM23 protein localization using immunohistochemistry and measured both mRNA and protein expression post-lesion with RT-qPCR and Western blot. ADAM23 is expressed in multiple cell types of the OE, including glial Sustentacular (Sus) cells and …

Prevalence And Diversity Of The Haemosporidian Blood Parasite Leucocytozoon In Sub-Saharan African Birds, Heather Skeen

Master's Theses

Our knowledge of avian Haemosporidian parasites has increased dramatically with the advent and increased used of molecular technologies. Yet Leucocytozoon, a common avian parasite, remains relatively understudied. Haemosporidian parasite diversity and prevalence has been shown to be dependent on several factors, including host family and habitat, on a microecological scale. In this study I screened 3,375 birds from sub-Saharan Africa for the presence of Leucocytozoon and demonstrate that the patterns of prevalence and diversity continue at a macroecological scale. Using molecular data, I found that the prevalence of Leucocytozoon varied between sampling areas from 3.9% to 62.64% and the diversity …

Lactobacillus Crispatus Produces A Bacteridical Molecule That Kills Uropathogenic E. Coli, Katherine Diebel

Master's Theses

As many as 1 in 2 women will have at least one urinary tract infection (UTI) in their lifetime. UTIs can cause complications in pregnancy and decrease quality of life, and their treatment and prevention are expensive. Uropathogenic E. coli (UPEC) is the primary cause of UTI. The probiotic and bactericidal capacities of gut and vaginal Lactobacillus isolates have been studied, but the same attention has not been paid to urinary strains. These urinary isolates of L. crispatus appear to have a greater killing capacity against UPEC and this bactericidal activity does not depend on the cells themselves, consistent with …

The Role Of C-Abl Kinase In Hcc Development, Lennox Chitsike

Master's Theses

Hepatocellular Carcinoma is the second most lethal cancer after pancreatic cancer. Unresectable HCC tumors carry a poor prognosis and few treatment options are available. The dismal prognosis is mainly due to limited therapy options and molecularly targeted therapy is deemed as solution. Here, we report a novel role of c-Abl in HCC development. We provide evidence of c-Abl activation in human HCC samples compared to normal liver. Using genetic and pharmacological tools, we show that c-Abl plays a vital role in HCC progression in vitro and in vivo. We have identified Axl as an effector in processes mediated by c-Abl. …

Influence Of Metaphoric Language On Juror Decision Making, Melissa Michelle David

Master's Theses

This paper examines the effects of metaphoric language on judgment, assessment and juror verdict decision making. It further examines potential interactions between the use of figurative language and defendant race on juror verdict decisions. Research has potential implications on how the recent cultural climate has changed racial biases within the realm of juror decision making.

Cellular Consequences Of Lysosomal Rupture Induced By Alpha Synuclein, Zachary Carpenter Green

Master's Theses

Misfolded, toxic forms of amyloid alpha synuclein (α-syn) have been implicated in Parkinson’s disease (PD) pathology and have been shown to spread throughout the brain in a prion-like manner, explaining the progressive loss of neurons in PD. The mechanisms of spread and cell death are unknown, however, evidence from previous studies suggests that neurons may undergo apoptosis due to the uptake of exogenous α-syn aggregate through the endocytic pathway and subsequent lysosomal rupture.

This study aimed to corroborate previous evidence of α-syn induced lysosomal rupture and investigate the cellular repercussions of rupture with respect to cell death and α-syn transfer. …

Estrogen Regulation Of Mir-181a Stability In Neurons, Chun Kim

Master's Theses

Estrogens are an important class of steroid hormones involved in many cellular signaling processes. Levels of estrogens fluctuate across the lifespan suggesting that they target intracellular mediators, such as microRNAs, to fine-tune homeostatic cellular processes. Previous work in our lab demonstrated that 17β-estradiol (E2), the predominant circulating estrogen, stabilized miR-181a in a neuronal cell line derived from rat hypothalamus. These results lead to the hypothesis that E2 regulated miR-181a stability by altering the pool of endogenous RNA and by recruiting PNRC2 away from the miRNA degradation machinery. By utilizing miRNA degradation assays and immunostaining techniques, it was determined that the …

Interfering In A Non-Interference Policy: Defining Star Trek's Prime Directive, Andrew Steele

Master's Theses

The aim of this thesis is to provide a comprehensive definition of the Prime Directive, a concept that was developed in Star Trek: The Original Series, as well as provide a non-fictionalized version of the edict.

The Prime Directive is an edict that governs Starfleet not to interfere with a society’s development.

The first main section will discuss in further detail why The Original Series account of the Prime Directive was selected. Furthermore, it will discuss how members of academia interpret the Prime Directive.

The second main section will be an episode-by-episode analysis of each Prime Directive centered episode to …

Early Round Goby (Neogobius Melanostomus) Invasion Into Lake Michigan Tributaries And Competitive Interactions With Two Native Benthic Fishes., Margaret Ann Malone

Master's Theses

The round goby is a prolific invasive species and is currently spreading into Great Lake tributary streams. There is a high potential for negative impacts on native benthic fishes in these stream habitats and the aim of this study is to assess the impacts of the round goby on two native darter species in particular (johnny darter and blackside darter). I review the history of round goby invasion in the Great Lakes and summarize hypotheses of the invasive characters of the round goby. Using game theory, I provide a G-function approach to understanding the outcomes of the round goby invasion …

Phosphodiesterase Inhibition As A Mechanism Of Ion Channel Modulation By Celecoxib, Christina Jean Robakowski

Master's Theses

The overall objective of this thesis work is to determine the mechanism by which celecoxib modulates Kv7 potassium channels in vascular smooth muscle cells. The central hypothesis of the project is that celecoxib modulates Kv7 potassium channels in vascular smooth muscle cells through inhibition of phosphodiesterase 4 (PDE4, which catalyzes the breakdown of cyclic adenosine monophosphate (cAMP)), thereby activating a cAMP/protein kinase A (PKA) signaling pathway. The aims of this thesis targeted different points in the cAMP/PKA pathway with pharmacological interventions using whole cell perforated patch clamp electrophysiology and biochemical methods.

The data suggest multiple mechanisms by which celecoxib could …

A Bioluminescence Sensor Of Nlrp3 Inflammasome Activation, Michael Alexander Winek

Master's Theses

The innate immune system is many organisms first line of defense against pathogenic insult or tissue damage. This defense strategy is intent on restoring homeostasis upon perturbation. Upon activation of the innate immune system in humans, an oligomeric protein complex termed the “Inflammasome” forms in myeloid cells. The canonical output of activation of any subset of inflammasome is Caspase-1-mediated secretion of pro-inflammatory cytokines IL1β and IL18. Chronic or uncontrolled inflammasome activation is at the core of myriad economically burdening diseases. In many of these diseases, endogenous factors chronically engage the innate immune system. To study these diseases in in vivo, …

Preliminary Investigation Of Commercially Available Pluronics As Uv Curable 3d Printing Inks For Tissue Engineering Applications, A'Lester Cordell Allen

Master's Theses

Three-dimensional printing (3DP) emerged from simple beginnings in the field of additive manufacturing (AM) over 31 years ago as an economical technique for rapid prototyping. Now 3DP has become the premier method for fabricating materials from unique consumer products to lifesaving customized human organs. Current challenges in bioprinting center around balancing material properties such as stiffness, yield strength, and surface chemistry with non-Newtonian fluid flow to construct interconnected, porous scaffolding geometries that simulate the complex vasculature found in the extracellular matrix (ECM) of the human body needed to promote cell growth and regeneration. In this study, several copolymers of poly(ethlyene …

Exploring Racial Diversity In Caldecott Medal-Winning And Honor Books, Angela Christine Moffett

Master's Theses

The Caldecott Medal, awarded annually by the American Library Association to the illustrator of the “most distinguished American picture book,” is the oldest and most prestigious award for children’s picture books in the United States. While the award winners have occasionally depicted racially diverse characters, it was not known to what extent the chosen winning titles have kept pace with changing racial demographics in the country. Diversity in children’s literature, and the lack thereof, has become a critical issue for our time. The social implications of failing to provide an exemplary collection of picture books and other literature representative of …