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LSU Doctoral Dissertations

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Asymptotic Formulae For Restricted Unimodal Sequences, Richard Alexander Frnka Jan 2017

Asymptotic Formulae For Restricted Unimodal Sequences, Richard Alexander Frnka

LSU Doctoral Dissertations

Additive enumeration problems, such as counting the number of integer partitions, lie at the intersection of various branches of mathematics including combinatorics, number theory, and analysis. Extending partitions to integer unimodal sequences has also yielded interesting combinatorial results and asymptotic formulae, which form the subject of this thesis. Much like the important work of Hardy and Ramanujan proving the asymptotic formula for the partition function, Auluck and Wright gave similar formulas for unimodal sequences. Following the circle method of Wright, we provide the asymptotic expansion for unimodal sequences with odd parts. This is then generalized to a two-parameter family of …


The Machine Gun Hand: Robots, Performance, And American Ideology In The Twentieth Century, Benjamin Michael Phelan Jan 2017

The Machine Gun Hand: Robots, Performance, And American Ideology In The Twentieth Century, Benjamin Michael Phelan

LSU Doctoral Dissertations

Twentieth-century Marxist philosopher Louis Althusser argued in his famous essay “Ideology and Ideological State Apparatuses” that capitalism reproduces itself by interpellating individuals as subjects. For Althusser, the subject has a dual definition: a person who imagines him or herself to be a free subject who then “chooses” capitalism, and a person who, once they have “chosen” capitalism, gives up their free will to the Subject (Law, God, Authority, the State). This dual definition of the subject mirrors the dual definition of “robot.” A robot is both a mechanical being that moves on its own and a person who acts in …


Atmospheric Boundary Layer Processes To Mimic Peak Pressures On Low-Rise Buildings: Cfd Versus Full-Scale And Wind Tunnel Measurements, Hamzeh Gol Zaroudi Jan 2017

Atmospheric Boundary Layer Processes To Mimic Peak Pressures On Low-Rise Buildings: Cfd Versus Full-Scale And Wind Tunnel Measurements, Hamzeh Gol Zaroudi

LSU Doctoral Dissertations

Realistic prediction of peak wind pressures is indispensable in a safe design of low-rise buildings. For several decades wind tunnel testing was employed to obtain wind loads on buildings and other structures. However, there is still doubt in the wind engineering community regarding the adequacy of wind tunnels to predict accurately full-scale pressures on low-rise buildings and small-size structures. The recommendations of the American Society of Civil Engineers (ASCE) 7-10 standard for external pressure coefficients, for roof components and cladding (C&C) design are also based on published wind tunnel data. Recent field measurements show significant deviation of full-scale pressures from …


Fluorescent Probe Interrogation Of A Cytoprotective Cancer-Linked Oxidoreductase In Two-Dimensional Human Cell Cultures And Solid Tumor Mimics, Bijeta Prasai Jan 2017

Fluorescent Probe Interrogation Of A Cytoprotective Cancer-Linked Oxidoreductase In Two-Dimensional Human Cell Cultures And Solid Tumor Mimics, Bijeta Prasai

LSU Doctoral Dissertations

Fluorescence molecular imaging is an emerging field with potential to aid in optically guided surgery for cancer treatment. To overcome the drawbacks of always-on fluorescent probes, such as indocyanine green, activatable fluorescent probes are being developed that allow high signal-to-background imaging for better discrimination of cancerous cells from normal cells. For activation, turn-on fluorescent probes rely on the presence of biomarkers such as antibodies, cell-surface receptors or enzymes that are highly specific to tumor cells. hNQO1 (human NAD(P)H: quinone oxidoreductase isoenzyme 1) is considered as one of such cancer-associated biomarkers that are present intracellularly in cancers of multiple origins. It …


Maintaining High Performance Across All Problem Sizes And Parallel Scales Using Microkernel-Based Linear Algebra, Md Rakib Hasan Jan 2017

Maintaining High Performance Across All Problem Sizes And Parallel Scales Using Microkernel-Based Linear Algebra, Md Rakib Hasan

LSU Doctoral Dissertations

Linear algebra underlies a large proportion of computational problems. With the continuous increase of scale on modern hardware, performance of small sized linear algebra has become increasingly important. To overcome the shortcomings of conventional approaches, we employ a new approach using a microkernel framework provided by ATLAS to improve the performance of a few linear algebra routines for all problem sizes. Our initial research consists of improving the performance of parallel LU factorization in ATLAS for which we were able to achieve up to 2.07x and 2.66x speedup for small problems, up to 91% and 87% of theoretical peak performance …


Resonant Interactions In Strong Field Laser Physics, Seth Jacob Camp Jan 2017

Resonant Interactions In Strong Field Laser Physics, Seth Jacob Camp

LSU Doctoral Dissertations

We present a theoretical study of the influence of resonant enhancement on high harmonic generation for harmonics near the ionization threshold of helium and argon atoms. This is done by solving the time-dependent Schrodinger equation (TDSE) for the interaction between an atom and a driving laser pulse. By varying parameters of the driving laser pulse, we are able to identify the enhancement of harmonics resulting from multiphoton resonances between the ground state and Stark-shifted excited states of the atom. In this way, spectral and temporal signatures of resonant enhancement are identified and highlighted. We also study trajectory dynamics in HHG. …


Exploring Teaching Approaches And Sociocultural Dynamics In The Middle And High School English Second Language Teaching Environment From The Perspective Of The Multicultural Educator, Nancy Laguna Luque Jan 2016

Exploring Teaching Approaches And Sociocultural Dynamics In The Middle And High School English Second Language Teaching Environment From The Perspective Of The Multicultural Educator, Nancy Laguna Luque

LSU Doctoral Dissertations

ABSTRACT The act of teaching in the middle and high school involves highly complex sociocultural dynamics in challenging environments. English second language specialists are the type of educators that closely work with the most at risk students in that context. This study explored middle and high school multicultural ESL instructors’ literacy delivery approaches, the understanding they have of difficulties in their field of action, and their particular awareness, interpretation of otherness and attitudes regarding the specific characteristics of their working milieu. This qualitative study utilized participant observation and Developmental Research Sequence (Spradley, 1980) as the systematic approach to gather and …


Molecularly Imprinted Polymers For Enantiomer Separations And Biomolecular Sensors, Britney Lyn Hebert Jan 2016

Molecularly Imprinted Polymers For Enantiomer Separations And Biomolecular Sensors, Britney Lyn Hebert

LSU Doctoral Dissertations

Molecularly Imprinted Polymers (MIPs) encompass a wide range of applications by changing the different components, e.g. the template, crosslinker or functional monomers. Of interest among these different applications are separations and sensors. Separations by MIPs traditionally use a chiral pure template but in some cases that chiral pure template may not be available for imprinting. Using chiral (N-α-bismethacyloyl-L-alanine) and achiral (N,O-bisacrylamide ethanolamine) crosslinkers we investigated imprinting of scalemic and racemic template mixtures of Boc-tyrosine enantiomers. The achiral and chiral crosslinkers yielded similar results for the partial separation of enantiomers by scalemic imprinted polymers because separation and recognition are not dependent …


Synthesis And Characterization Of Polyhalogenated Boron Dipyrromethenes And Carboranylbisthiophene Oligomers, Ning Zhao Jan 2016

Synthesis And Characterization Of Polyhalogenated Boron Dipyrromethenes And Carboranylbisthiophene Oligomers, Ning Zhao

LSU Doctoral Dissertations

Chapter 1 of this dissertation shows a brief overview of fundamental concepts and classic synthetic routes of BODIPY dyes. The synthetic strategies and various application (e.g. PDT sensitizers and fluorescent indicators) of halogenated BODIPYs are also presented in this chapter. Chapters 2-4 describe the synthesis of three new polyhalogenated BODIPY platforms and their regioselective functionalization. Such new platforms provide new methodologies for producing both symmetric and asymmetric BODIPYs. Pd(0)-catalyzed cross-couplings and aromatic substitution reactions were applied to investigate the reactivity and regioselectivity of different halogen groups on the BODIPY platforms. The studies showed that the reactivity order of the halogens …


Scheduling And Tuning Kernels For High-Performance On Heterogeneous Processor Systems, Ye Fang Jan 2016

Scheduling And Tuning Kernels For High-Performance On Heterogeneous Processor Systems, Ye Fang

LSU Doctoral Dissertations

Accelerated parallel computing techniques using devices such as GPUs and Xeon Phis (along with CPUs) have proposed promising solutions of extending the cutting edge of high-performance computer systems. A significant performance improvement can be achieved when suitable workloads are handled by the accelerator. Traditional CPUs can handle those workloads not well suited for accelerators. Combination of multiple types of processors in a single computer system is referred to as a heterogeneous system. This dissertation addresses tuning and scheduling issues in heterogeneous systems. The first section presents work on tuning scientific workloads on three different types of processors: multi-core CPU, Xeon …


Design, Synthesis And Biological Applications Of Polypeptoids And Boron Dipyrromethenes, Sunting Xuan Jan 2016

Design, Synthesis And Biological Applications Of Polypeptoids And Boron Dipyrromethenes, Sunting Xuan

LSU Doctoral Dissertations

The dissertation is about the design, synthesis and biological applications of polypeptoids and boron dipyrromethenes (BODIPYs). The dissertation is divided into seven chapters reporting various aspects of the background to my field of study and the results obtained during my PhD program. Chapter 1 is a concise overview of the fundamental concepts of polypeptoids and hydrogels, as well as their recent developments on synthetic strategies, property investigations, and biological applications in different fields. Chapter 2 presents the design, synthesis and potential application as tissue engineering scaffold of thermoreversible ABC polypeptoid hydrogels. A series of ABC copolypeptoids were synthesized and their …


On The Degradation Of Lubricating Grease, Asghar Rezasoltani Jan 2016

On The Degradation Of Lubricating Grease, Asghar Rezasoltani

LSU Doctoral Dissertations

A comprehensive literature review on physical and chemical degradation monitoring and life estimation models for lubricating greases is presented in chapter one. Degradation mechanisms for lubricating grease are categorized and described, and an extensive survey of the available empirical and analytical grease life estimation models including degradation monitoring standards and methods are presented. In chapter two, irreversible thermodynamic theory is employed to study the mechanical degradation of lubricating grease. A correlation between the mechanical degradation and entropy generation is established and the results are verified experimentally using a rheometer, a journal bearing test rig, and a modified grease worker machine. …


A Novel Recurrent Convolutional Neural Network For Ocean And Weather Forecasting, Robert James Firth Jan 2016

A Novel Recurrent Convolutional Neural Network For Ocean And Weather Forecasting, Robert James Firth

LSU Doctoral Dissertations

Numerical weather prediction is a computationally expensive task that requires not only the numerical solution to a complex set of non-linear partial differential equations, but also the creation of a parameterization scheme to estimate sub-grid scale phenomenon. The proposed method is an alternative approach to developing a mesoscale meteorological model – a modified recurrent convolutional neural network that learns to simulate the solution to these equations. Along with an appropriate time integration scheme and learning algorithm, this method can be used to create multi-day forecasts for a large region. The learning method presented is an extended form of Backpropagation Through …


Scanning Probe Investigations Of Multidentate Thiol And Spatially Confined Porphyrin Nanoassemblies Using Nanoscale Lithography, Xianglin Zhai Zhai Jan 2016

Scanning Probe Investigations Of Multidentate Thiol And Spatially Confined Porphyrin Nanoassemblies Using Nanoscale Lithography, Xianglin Zhai Zhai

LSU Doctoral Dissertations

Approaches to prepare spatially selective surfaces were developed in this dissertation for constructing nanopatterns of organic thin film materials. Nanoscale surface patterns were prepared using immersion particle lithography and scanning probe lithography combined with organothiol chemistry. Organic thin films and nanomaterials can be patterned with tunable periodicities and designed shapes by selecting the diameter of mesospheres used as surface masks or scanning probe lithography, respectively. The surface platforms of well-defined nanopatterns are ideal for high resolution investigations using scanning probe microscopy (SPM). Local measurements of surface properties and conductive properties combined with nanolithography were accomplished at the molecular level. Sample …


On Properties Of Matroid Connectivity, Simon Pfeil Jan 2016

On Properties Of Matroid Connectivity, Simon Pfeil

LSU Doctoral Dissertations

Highly connected matroids are consistently useful in the analysis of matroid structure. Round matroids, in particular, were instrumental in the proof of Rota's conjecture. Chapter 2 concerns a class of matroids with similar properties to those of round matroids. We provide many useful characterizations of these matroids, and determine explicitly their regular members. Tutte proved that a 3-connected matroid with every element in a 3-element circuit and a 3-element cocircuit is either a whirl or the cycle matroid of a wheel. This result led to the proof of the 3-connected splitter theorem. More recently, Miller proved that matroids of sufficient …


Properties Of Polynomial Identity Quantized Weyl Algebras, Jesse S. F. Levitt Jan 2016

Properties Of Polynomial Identity Quantized Weyl Algebras, Jesse S. F. Levitt

LSU Doctoral Dissertations

In this work on Polynomial Identity (PI) quantized Weyl algebras we begin with a brief survey of Poisson geometry and quantum cluster algebras, before using these as tools to classify the possible centers of such algebras in two different ways. In doing so we explicitly calculate the formulas of the discriminants of these algebras in terms of a general class of central polynomial subalgebras. From this we can classify all members of this family of algebras free over their centers while proving that their discriminants have the properties of effectiveness and local domination. Applying these results to the family of …


Biomass Gasification For Electricity Generation: An Integrated Approach For Development Of Forest Residue-Based Projects In Rural India, Anand Mishra Jan 2016

Biomass Gasification For Electricity Generation: An Integrated Approach For Development Of Forest Residue-Based Projects In Rural India, Anand Mishra

LSU Doctoral Dissertations

Biomass gasification is generally regarded as a promising technology for various advanced application in energy production. Biomass is the only carbon-based sustainable option among the renewable energy sources. This study is focused on fostering biomass gasification for electricity generation sector in India. The study addresses four broad aspects of biomass gasification for electricity generation - feedstock properties and gasification technology, policy and regulatory framework governing the sector, financial evaluation of electricity generation from biomass gasification, and feedstock supply. The study is divided in four chapters, each of which addresses one aspect of electricity generation through biomass gasification. Based on literature, …


Spectral Properties Of Photonic Crystals: Bloch Waves And Band Gaps, Robert Paul Viator Jr Jan 2016

Spectral Properties Of Photonic Crystals: Bloch Waves And Band Gaps, Robert Paul Viator Jr

LSU Doctoral Dissertations

The author of this dissertation studies the spectral properties of high-contrast photonic crystals, i.e. periodic electromagnetic waveguides made of two materials (a connected phase and included phase) whose electromagnetic material properties are in large contrast. A spectral analysis of 2nd-order divergence-form partial differential operators (with a coupling constant k) is provided. A result of this analysis is a uniformly convergent power series representation of Bloch-wave eigenvalues in terms of the coupling constant k in the high-contrast limit k -> infinity. An explicit radius of convergence for this power series is obtained, and can be written explicitly in terms of the …


Tip-Enhanced Laser Ablation Sample Transfer For Mass Spectrometry, Chinthaka Aravinda Seneviratne Jan 2016

Tip-Enhanced Laser Ablation Sample Transfer For Mass Spectrometry, Chinthaka Aravinda Seneviratne

LSU Doctoral Dissertations

In this research, atomic force microscope tip-enhanced laser ablation mass spectrometry (AFM TELA-MS), an ambient sub-micrometer scale sampling method for offline MS was developed. AFM TELA was used to transfer molecules from thin films to a suspended silver wire for off-line mass spectrometry using laser desorption ionization (LDI) and matrix-assisted laser desorption ionization (MALDI). An AFM with a 30 nm radius gold-coated silicon tip was used to image the sample and to hold the tip 15 nm from the surface for material removal using a pulsed Nd:YAG laser, which provides output at wavelengths of 532 nm in the visible, 1064 …


Thin Films Of Semiconducting Polymers And Block Copolymers By Surface-Initiated Polymerization, Sang Gil Youm Jan 2016

Thin Films Of Semiconducting Polymers And Block Copolymers By Surface-Initiated Polymerization, Sang Gil Youm

LSU Doctoral Dissertations

The ability to control nanoscale morphology and molecular organization in organic semiconducting polymer thin films is an important prerequisite for enhancing the efficiency of organic thin-film devices, including organic light-emitting and photovoltaic devices. The current “top-down” paradigm for making such devices is based on utilizing solution-based processing (e.g. spin-casting) of soluble semiconducting polymers. This approach typically provides only modest control over nanoscale molecular organization and polymer chain alignment. A promising alternative to using solutions of pre-synthesized semiconducting polymers pursues instead a “bottom-up” approach to prepare surface-grafted semiconducting polymer thin films by surface-initiated polymerization of small-molecule monomers. This dissertation mainly focuses …


Ecological-Hydrological Feedback In Forested Wetlands, Scott Thomas Allen Jan 2016

Ecological-Hydrological Feedback In Forested Wetlands, Scott Thomas Allen

LSU Doctoral Dissertations

In forested wetlands, the biotic and abiotic consequences of water level variability is not well understood. The effects of flooding on carbon and water exchanges are important knowledge gaps where progress could benefit management of natural resources and predicting of changes in surface geophysical cycles. Two specific needs are a better understanding of (1) wetland tree responses to hydrologic variations, and (2) the effects of the forest and associated tree stressors on surface energy and water fluxes. Objectives were to determine effects of flooding on evaporation rates and energy dynamics, tree water use and growth responses to river-floodplain connectivity and …


An Examination Of Students' Perceptions Of The Louisiana Act Mandate On Their Postsecondary Education Decisions, Thelma Carol Purnell Jan 2016

An Examination Of Students' Perceptions Of The Louisiana Act Mandate On Their Postsecondary Education Decisions, Thelma Carol Purnell

LSU Doctoral Dissertations

In the United States,the American College Test (ACT)is a standardized test that is used primarily as an indicator of college readiness and as a gauge for college admission. The governing bodies for Louisiana’s public schools—The Louisiana Department of Education (LDOE)and the Board of Elementary and Secondary Education (BESE)—made the ACT a requirement—effective spring 2013—for Louisiana’s public high school 11th grade students regardless of their postsecondary intentions. The primary purpose of this study was to ascertain from Louisiana high school seniors’ whether the Louisiana Department of Education’s ACT mandate is perceived as a factor influencing their postsecondary decisions or affecting their …


Garbage Collection For General Graphs, Hari Krishnan Jan 2016

Garbage Collection For General Graphs, Hari Krishnan

LSU Doctoral Dissertations

Garbage collection is moving from being a utility to a requirement of every modern programming language. With multi-core and distributed systems, most programs written recently are heavily multi-threaded and distributed. Distributed and multi-threaded programs are called concurrent programs. Manual memory management is cumbersome and difficult in concurrent programs. Concurrent programming is characterized by multiple independent processes/threads, communication between processes/threads, and uncertainty in the order of concurrent operations. The uncertainty in the order of operations makes manual memory management of concurrent programs difficult. A popular alternative to garbage collection in concurrent programs is to use smart pointers. Smart pointers can collect …


Application Of Biomass Derived Materials In Nanocomposites And Drilling Fluids, Kunlin Song Jan 2016

Application Of Biomass Derived Materials In Nanocomposites And Drilling Fluids, Kunlin Song

LSU Doctoral Dissertations

Tar is inevitably produced from biomass thermochemical processes, and is often disposed as an industrial waste, leading to environmental pollution. As a result of its high carbon content, tar was expected to be a promising precursor for manufacturing carbon materials. Consequently, low-cost porous carbon nanofibers (CNFs) using tar, polyacrylonitrile (PAN), and silver nanoparticles was fabricated through electrospinning and subsequent stabilization and carbonization processes. The continuous electrospun nanofibers were obtained with diameters ranging from 392 to 903 nm. The addition of biomass tar resulted in increased fiber diameters, reduced thermal stabilities, and slowed cyclization reactions of PAN in the as-spun nanofibers. …


Geologic Extremes Of The Nw Himalaya: Investigations Of The Himalayan Ultra-High Pressure And Low Temperature Deformation Histories, Dennis Girard Donaldson Jan 2016

Geologic Extremes Of The Nw Himalaya: Investigations Of The Himalayan Ultra-High Pressure And Low Temperature Deformation Histories, Dennis Girard Donaldson

LSU Doctoral Dissertations

This dissertation focuses on two extremes of orogenic development in the Himalaya: the timing of early ultra-high pressure related tectonics and the subsequent emplacement of the high grade Greater Himalayan Crystallines. The Himalayan orogeny is one of if not the best example of ongoing collisional systems, marked by the ongoing convergence of the Indian and Asian continents. The presence of coesite in the Tso Morari complex respresents subduction of the Indian continental crust to ultrahigh-pressure (UHP) conditions. However, the timing of UHP metamorphism is debated, creating an uncertainty in the calculation of subduction and exhumation rates. Petrologic and geochronologic analyses …


Fairness And Approximation In Multi-Version Transactional Memory., Basem Ibrahim Assiri Jan 2016

Fairness And Approximation In Multi-Version Transactional Memory., Basem Ibrahim Assiri

LSU Doctoral Dissertations

Shared memory multi-core systems bene_x000C_t from transactional memory implementations due to the inherent avoidance of deadlocks and progress guarantees. In this research, we examine how the system performance is a_x000B_ected by transaction fairness in scheduling and by the precision in consistency. We _x000C_rst explore the fairness aspect using a Lazy Snapshot (multi-version) Algorithm. The fairness of transactions scheduling aims to balance the load between read-only and update transactions. We implement a fairness mechanism based on machine learning techniques that improve fairness decisions according to the transaction execution history. Experimental analysis shows that the throughput of the Lazy Snapshot Algorithm is …


Curriculum And Compassion: An Inquiry Into The Relevance Of The Charism Of The Brothers Of The Sacred Heart In A Post-Modern World, Thomas Walter Eldringhoff Jan 2016

Curriculum And Compassion: An Inquiry Into The Relevance Of The Charism Of The Brothers Of The Sacred Heart In A Post-Modern World, Thomas Walter Eldringhoff

LSU Doctoral Dissertations

The purpose of this study is to examine the relevance of a curriculum that embodies the charism of the Brothers of the Sacred Heart in a post-modern world. The project will investigate the understanding of the charism both by the researcher and by selected brothers who are in unique positions to articulate and explicate just what the charism entails. A variety of formational and foundational documents will also be subjected to philosophical analysis so a deep picture of the charism is available to the reader. Literature surrounding post-modernist curriculum theory serves as the theoretical framework for this investigation of the …


Mathematical Scaling And Statistical Modeling Of Geopressured Geothermal Reservoirs, Esmail Ansari Jan 2016

Mathematical Scaling And Statistical Modeling Of Geopressured Geothermal Reservoirs, Esmail Ansari

LSU Doctoral Dissertations

The interest for developing geopressured-geothermal reservoirs along the US Gulf Coast is increasing for securing energy needs and reducing global warming. Identifying the most attractive candidate reservoirs for geothermal energy production requires quick and simple models. Analytical models are not always available and simulating each case individually is expensive. The use of scaling and statistical modeling is one approach to translate the output of a simulator into quick models with general applicability at all scales. The developed models can quickly estimate temperature and thermal energy recovery from the geopressured-geothermal reservoirs. These models can screen large databases of reservoirs to select …


A Mixed Methods Case Study Exploring Simulation And Caring In Nursing Education, Carla Armstead Harmon Jan 2016

A Mixed Methods Case Study Exploring Simulation And Caring In Nursing Education, Carla Armstead Harmon

LSU Doctoral Dissertations

Current research in nursing education suggests a shift from traditional didactic transmission methods to student-centered pedagogies to prepare nursing students with substantive knowledge necessary for competent practice in a complex healthcare environment. Simulation has emerged as a pedagogy that offers students the opportunity to critically think, solve problems, and care for diverse patients in a nonthreatening, safe environment. As the use of simulation increases, a concern is whether or not it can hinder the development of caring behaviors necessary for competent and compassionate nursing practice. This research was a study of nursing students’ descriptions of the simulation experience, and perceptions …


Quantitative Oil Source-Fingerprinting Techniques And Their Application To Differentiating Crude Oil In Coastal Marsh Sediments, Buffy Marie Meyer Jan 2016

Quantitative Oil Source-Fingerprinting Techniques And Their Application To Differentiating Crude Oil In Coastal Marsh Sediments, Buffy Marie Meyer

LSU Doctoral Dissertations

Oil source-fingerprinting is an environmental forensics technique that uses analytical chemistry to determine the origin of oil residues in environmental samples by comparison to a known or suspected source oil. Currently, the only standardized method for oil source fingerprinting is a qualitative approach that is very effective in almost every oil spill response situation. However, the need for quantitative oil source-fingerprinting methods to complement the qualitative determinations is extremely desired. The research herein aims to utilize data generated by gas chromatography/mass spectrometry (GC/MS) methodologies to test two different quantitative techniques: diagnostic biomarker ratio analysis and chemometrics. The most common crude …