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The Role Of Ad-36 And Its E4orf-1 Protein In Modulating Glycemic Control, Emily Jane Dhurandhar
The Role Of Ad-36 And Its E4orf-1 Protein In Modulating Glycemic Control, Emily Jane Dhurandhar
LSU Doctoral Dissertations
Current treatment strategies for Type 2 Diabetes Mellitus (T2DM) include a range of anti-diabetic drugs, supplemented by lifestyle modifications to reduce dietary fat intake and body fat. However, for their anti-diabetic action, most drugs recruit insulin signaling pathways, which are already impaired in T2DM. Also, compliance and success in achieving sustained improvements in diet or obesity over the long term is marginal. Therefore, an agent that improves diabetes independent of insulin signaling or lifestyle changes may be highly useful. Human adenovirus Ad36 offers such a model. Ad36 improves glycemic control in chow-fed mice or rats and attenuates diabetes and hepatic …
When The Saints Go Marching In: An Ethnography Of Volunteer Tourism In Post-Hurricane Katrina New Orleans, Jennifer Lea Erdely
When The Saints Go Marching In: An Ethnography Of Volunteer Tourism In Post-Hurricane Katrina New Orleans, Jennifer Lea Erdely
LSU Doctoral Dissertations
This original study examines a new phenomenon in New Orleans tourism. Since Hurricane Katrina hit in late August 2005, droves of individuals and groups have come to New Orleans to help rebuild the city. Through conducting fifty interviews with these individuals from 2008-2009, the author traces the steps of volunteer tourists in post-Hurricane Katrina New Orleans. This study investigates the experiences of volunteer tourists. Additionally, the author immersed herself with volunteer tourism groups to experience volunteering and the groups herself. Through careful inspection of original interviews with volunteer tourists, the author discovers how the volunteer tourists contribute to the city …
The Hegemony Of Language - Literary Writing And The Quest For Subjectivity In The Works Of Michel De Montaigne And Charles Ferdinand Ramuz, Carla Bota Vance
The Hegemony Of Language - Literary Writing And The Quest For Subjectivity In The Works Of Michel De Montaigne And Charles Ferdinand Ramuz, Carla Bota Vance
LSU Doctoral Dissertations
Starting from the premise that one’s identity is first and foremost construed in language, this dissertation argues that language is the fundamental site of resistance for writers who define themselves through linguistic difference. Recognizing also that language and literary production frequently fall under the control of complex authorities, this thesis examines literature as a site where confrontation is played out aesthetically. Literary writing, in other words, is exposed as a point of intersection between writers whose language draws its sources from a peripheral location and the centers of authority that regulate and dictate what is accepted as artistically and culturally …
In The Ruins Of Zine Pedagogy: A Narrative Study Of Teaching With Zines, Karin H. Degravelles
In The Ruins Of Zine Pedagogy: A Narrative Study Of Teaching With Zines, Karin H. Degravelles
LSU Doctoral Dissertations
This study considers the educational significance of zines—small circulation, self-published magazines—by asking how educators who teach with zines encounter and negotiate zine pedagogy. Though the literature on zines and teaching describes many potential benefits, it also describes contradictions and failures, with some researchers even going so far as to claim that “zines do not belong in classrooms” (Guzzetti, Elliott, & Welsch, 2010, p. 71). Through this dissertation, I investigate and complicate these claims by examining the stories and perspectives of teacher/zinesters—educators who teach or have taught with zines in a classroom setting. The project is situated within theories of the …
Modern Myth In Performance: Claiming Identity Through A Reading Of Fantasy Withcraft, Jessica Satterwhite Gray
Modern Myth In Performance: Claiming Identity Through A Reading Of Fantasy Withcraft, Jessica Satterwhite Gray
LSU Doctoral Dissertations
In this dissertation, I create a Wiccan dramaturgical lens to analyze three key fantasy sites: The Wizard of Oz film and stage adaptations (especially the Broadway musical Wicked), The Chronicles of Narnia film and theatrical adaptations, and the Harry Potter films and paratheatrical adaptations. These three fantasy stories have significant cultural impact and strong images of folkloric witches. My alternative reading shows how a subgroup can appropriate popular images for their own identity formation. I will analyze how signs, themes, and narrative tropes that otherwise seem ancillary or even anti-witch become highlighted and privileged, creating a different but equally legitimate …
Transatlantic Baggage: Expatriate Paris, Modernism, And The Apprenticeship Of Ernest Hemingway, Patrick Blair Bonds
Transatlantic Baggage: Expatriate Paris, Modernism, And The Apprenticeship Of Ernest Hemingway, Patrick Blair Bonds
LSU Doctoral Dissertations
“Transatlantic Baggage: Expatriate Paris, Modernism, and the Apprenticeship of Ernest Hemingway” argues that Hemingway’s expatriation and apprenticeship in modernist Paris from 1921-1925 provided an important impetus for his explorations in gender alterity. The project focuses on a critical-biographical rethinking of Hemingway’s literary development, integrating previous Hemingway biography and gender studies scholarship with new revelations from the manuscript of the forthcoming first two volumes of the Cambridge Edition of the Letters of Ernest Hemingway. An updated study of the author’s literary formation is long overdue; Charles Fenton’s The Apprenticeship of Ernest Hemingway: The Early Years (1954), for example, has served for …
Writing William Burroughs, Performing The Archive, John Lebret
Writing William Burroughs, Performing The Archive, John Lebret
LSU Doctoral Dissertations
Between 1958 and 1972, author William S. Burroughs undertook a series of radical experiments with alternative compositional modes based on the aleatory form of the Cut-up. Burroughs sold the entirety of his work from the period, assembled into an archive, to a collector in 1972. This study uses performative writing to document a year of archival research in Burroughs' collection, currently housed by The Henry W. and Albert A. Berg Collection of English and American Literature at the New York Public Library. Melding Bakhtin's theories of the chronotope and the grotesque body with creative writing and experimental modes of scholarly …
Edaphic And Vegetative Controls On Mercury Cycling In Oligohaline Wetlands, Jonathan M. Willis
Edaphic And Vegetative Controls On Mercury Cycling In Oligohaline Wetlands, Jonathan M. Willis
LSU Doctoral Dissertations
With the expansion of the human population and associated industries there is a concomitant increase in both resource utilization and the production of waste and deleterious by-products. Mercury is a naturally-occurring toxic metal with a complicated and unique biogeochemical cycle, and is often a contaminant of ecotoxicological concern in unindustrialized aquatic habitats. The research described herein was designed to elucidate multiple aspects regarding the behavior of mercury in oligohaline wetland habitats, particularly with respect to edaphic and vegetative effects, through a monitoring and characterization study as well as a series of manipulative experiments. The observational study, conducted in the wetlands …
Designing Irishness: Ethnicity, Heritage, And Imagined Connection To Place Through Language, Thomas James Sullivan
Designing Irishness: Ethnicity, Heritage, And Imagined Connection To Place Through Language, Thomas James Sullivan
LSU Doctoral Dissertations
In North America, those who are descended from "old world" immigrant groups—for example Germans, Greeks, Italians, Poles, and Irish—are thought to be assimilated or acculturated into the mainstream American culture. Since the late 1970s, however, sociologists have observed how a number of white ethnics, particularly those descended from third- and fourth-generation (and beyond) immigrants, continue to maintain a link to an ethnic group. This phenomenon—labeled symbolic or optional ethnicity—is now seen as a latter-stage development in the larger process of assimilation and ethnic-group identification. In this dissertation I show how the meaning of Irish identity has evolved in North America …
Paths Of Most Resistance: Navigating The Culture Industry In William Faulkner, Richard Wright, Delmore Schwartz, And Eudora Welty, Jason Dupuy
LSU Doctoral Dissertations
This dissertation explores how four modernist writers of the 1930s and 1940s—William Faulkner, Richard Wright, Delmore Schwartz, and Eudora Welty—used their works to present ways to resist and navigate what they present as the frequently reductive worldview offered by the culture industry. Faulkner tends to show the culture industry as selling easy answers that focus on the end result, which allows his characters to approach the culture industry with a sense of fatalism. To resist this, Faulkner stresses a step-by-step, complex dialectical understanding of the culture industry, one that shows the fissures in its seemingly straightforward narratives and allows the …
The Power Struggle Between Americans And Creoles In The First Half Of The Nineteenth Century And Its Influence On The Architecture Of New Orleans, Sylvia Starns Mince
The Power Struggle Between Americans And Creoles In The First Half Of The Nineteenth Century And Its Influence On The Architecture Of New Orleans, Sylvia Starns Mince
LSU Doctoral Dissertations
In the first half of the nineteenth century the house types of the landscape and the footprint of New Orleans changed dramatically. Many of the changes can be attributed to the influx of the refugees from Saint Domingue and the Americans who immigrated from the North and the East Coast of the United States. Both sets of influxes reflect the impact of these two immigrant groups on the previously existing power structures in economics, politics, and society of the city. While the refugees from Saint Domingue more or less assimilated into the city, and in doing so, achieved power over …
Regional Narratives, Hidden Maps, And Storied Places: Cultural Cartographies Of The Cariri Region, Northeast Brazil, Jorn Seemann
Regional Narratives, Hidden Maps, And Storied Places: Cultural Cartographies Of The Cariri Region, Northeast Brazil, Jorn Seemann
LSU Doctoral Dissertations
In recent years, maps and mappings have gained increasing attention in cultural-geographic studies. However, little has been written about how to employ cartographic products and processes as research methodologies in practice. In this dissertation I present four different qualitative mapping strategies that I label cultural cartographies and that aim to critically investigate the relations between geographical knowledge and representation, society and cartography, culture and maps. A region in Northeast Brazil, the Cariri in the state of Ceará, was selected as the space to test these strategies and to show how maps (both historic and contemporary and in their metaphorical sense) …
The Dialogism Of Self And Other In Contemporary American Drama, Shih-Yi Huang
The Dialogism Of Self And Other In Contemporary American Drama, Shih-Yi Huang
LSU Doctoral Dissertations
This work is interdisciplinary in orientation and brings together American theatre (and culture) and contemporary ethical philosophy. I am introducing the French philosopher Emmanuel Lévinas and his theory of Self and Other to an analysis of contemporary American drama—a mode of approach that is new to the discipline of theatre studies. Lévinas’s insights are particularly relevant to the concerns of the 21st century and how we might rethink relationships and values. My work looks at contemporary American plays in terms of nationalism, gender politics, racial dynamics and ecological issues. I contend that these playwrights are attempting to go beyond conventional …
Genetic And Cytological Investigation Of Nucleostemin-1 In Drosophila Melanogaster, Raphyel Ojomo Rosby
Genetic And Cytological Investigation Of Nucleostemin-1 In Drosophila Melanogaster, Raphyel Ojomo Rosby
LSU Doctoral Dissertations
Mammalian nucleostemin (NS) is a nucleolar GTP-binding protein implicated in cell cycle progression, stem cell proliferation, and ribosome assembly. Drosophila melanogaster contains a four-member nucleostemin family (NS1-4). Nucleostemin 1 (NS1) is the closest orthologue to human NS; it shares 33% identity and 67% similarity with human NS. We show that NS1 has intrinsic GTPase and ATPase activity, and that it is present within nucleoli of most larval and adult cells. Endogenous NS1 and lightly expressed GFP-NS1 enrich within the nucleolar granular regions as expected, while over-expressed GFP-NS1 localizes throughout the nucleolus and nucleoplasm, and to several transcriptionally active inter-bands of …
"It's Not Just About The Buildings, It's About The People": Architecture Practice, And Preservation In Post-Katrina New Orleans, Bethany W. Rogers
"It's Not Just About The Buildings, It's About The People": Architecture Practice, And Preservation In Post-Katrina New Orleans, Bethany W. Rogers
LSU Doctoral Dissertations
Drawing on the legacy of architectural studies in cultural geography, this dissertation integrates traditional approaches to built environments that take seriously the physical form and presence of buildings with more recent scholarship that employs performance and practice theory to address the embodied, contingent, and ongoing practices through which buildings are endowed with meaning by those who use, inhabit, or identify with them. Using ethnographic and architectural-documentation methods to carefully apprehend the interrelationships between architecture and embodied practices, this dissertation presents a set of ethno-material case studies – four buildings and their community of users that were central to New Orleans’ …
The Indigenous Culture Of School Mathematics In China And The United States: A Comparative Study Of Teachers' Understanding Of Constructivism, Lingqi Meng
LSU Doctoral Dissertations
This study aimed to explore how the indigenous (national) culture of teaching and learning mediates teachers’ understandings of constructivism in China and the U.S. Thirty middle school math teachers who are self-identified with the mathematics teaching reform movement in each country participated in this study (NCTM 2000 Math Standards in the United States or the MOE 2001 Math Standards in China). Both theoretical and empirical methods were adopted for this research. Theoretical analysis led to a new cultural model that helped select appropriate cultural elements for this study. Based on emergence theory, the new model perceives Confucianism and Taoism as …
The Virgin's Daughters: Catholic Traditions And The Post-Colonial South In Contemporary Women's Writing, Elizabeth M. Beard
The Virgin's Daughters: Catholic Traditions And The Post-Colonial South In Contemporary Women's Writing, Elizabeth M. Beard
LSU Doctoral Dissertations
This dissertation analyzes the texts of contemporary women writers who consciously engage dominant Catholic, American, and southern ideologies in their narratives and who posit Louisiana as a liminal, hybrid space. Building upon postcolonial concepts of hybridity and performance of cultural memory, I trace a “pathway” to feminist recovery and reclamation of ancestral memory and spirituality in Valerie Martin’s A Recent Martyr, Rebecca Wells’ Little Altars Everywhere and Divine Secrets of the Ya-Ya Sisterhood, Brenda Marie Osbey’s All Saints, and Erna Brodber’s Louisiana. The authors enact spiritual and cultural reclamation through the written expression of key components of postcolonial reconstruction of …
Phytochemical Analyses Of Bioactive Compounds In The Roots Of Cassia Alata Linn And The Anti-Angiogenic Evaluation Of Rhein As A Therapeutic Agent Against Breast Cancer Cells, Vivian Esther Fernand
Phytochemical Analyses Of Bioactive Compounds In The Roots Of Cassia Alata Linn And The Anti-Angiogenic Evaluation Of Rhein As A Therapeutic Agent Against Breast Cancer Cells, Vivian Esther Fernand
LSU Doctoral Dissertations
The research presented in this dissertation includes the novel phytochemical analysis of root extracts of Cassia alata L. and the anti-angiogenic evaluation of rhein in the treatment of breast cancer. To conduct these studies a combination of analytical techniques were employed, namely, chromatographic, spectroscopic, and bioanalytical. The first part of this research is focused on the phytochemical analysis of C. alata root extracts. A high performance liquid chromatography method was developed and validated for the determination of six phenolic compounds in the root extracts. The investigated compounds were identified by their ultraviolet spectra. Additionally, the presence of these phenolics was …
The Acquisition Of Pragmatic Competence: Compliment Response Strategies In Learners Of Spanish, James Bryant Smith
The Acquisition Of Pragmatic Competence: Compliment Response Strategies In Learners Of Spanish, James Bryant Smith
LSU Doctoral Dissertations
The areas of Pragmatics and Second Language Acquisition have existed separately in the field of Linguistics for some time. Their connection, however, has more recently seen a great deal of study by researchers like Scarcella and Brunak (1981), Rintell (1981), Brown and Levinson (1987), Koike (1992, 1996), Saito, Beecken (1997), Félix-Brasdefer (2003, 2006) and Huth (2006). A common thread in these studies is the effect of language transfer or cross-linguistic influence that the first language has while learners are attempting to acquire the pragmatic and politeness principles that are central to the target language and culture. One speech act that …
Religion And Realism In Late Nineteenth-Century American Literature, Lisa Irene Moody
Religion And Realism In Late Nineteenth-Century American Literature, Lisa Irene Moody
LSU Doctoral Dissertations
A critical approach to understanding the analytical power of realism and its representational claims in the late nineteenth-century is to examine the relationship between realism and a common cultural concern that opposes the very tenets of realism, one that necessarily pervaded all aspects of class, gender, nationality, race, sexual orientation, or other classifiable subsets of society typically linked with various schools of literary theory: the subject of religion. In fact, religion, with its disembodied immaterialism, surely the antithesis of realism, represents a unique cultural problem that tests the conceptual biases of the realist mode. One basic issue is that religion …
Experimental Design, Synthesis And Application Of Molecular Micelle Modified Polymeric Nanoparticles For Drug Delivery Systems And Free Radical Detection, Gabriela M. Ganea Visser
Experimental Design, Synthesis And Application Of Molecular Micelle Modified Polymeric Nanoparticles For Drug Delivery Systems And Free Radical Detection, Gabriela M. Ganea Visser
LSU Doctoral Dissertations
Biodegradable and biocompatible polymeric nanoparticles such as poly (lactide-co-glycolide) (PLGA) nanoparticles have been extensively studied as drug delivery systems for a variety of pharmaceutical agents. Nanoparticle surface properties are primarily determined by the emulsifiers used in the synthesis process, which have a significant impact on nanoparticle physico-chemical and biological properties. Anionic amino acid – based molecular micelles were used in the emulsification process to prepare monodisperse, small (below 100 nm) PLGA nanoparticles with a well defined spherical shape. Such molecular micelle – modified nanoparticles were used as drug carriers for delivery of antioxidants. Thymoquinone is a natural antioxidant, and an …
Peptide Targeting Of Platinum Anti-Cancer Drug And Synthesis Of Water Soluble Monofunctional Pt(Ii) Complexes Useful For Biological Labeling, Margaret W. Ndinguri
Peptide Targeting Of Platinum Anti-Cancer Drug And Synthesis Of Water Soluble Monofunctional Pt(Ii) Complexes Useful For Biological Labeling, Margaret W. Ndinguri
LSU Doctoral Dissertations
Platinum has been used as an inorganic medicinal agent with various applications such as anti cancer agents. Several new targeted Pt(II) conjugates were synthesized having the NGR and LHRH targeting motif. The platinum conjugates bearing the NGR motif revealed selective delivery and destruction of cancer cells that had CD13 receptors compared to untargeted carboplatin drug. The development of targeted chemotherapeutic has opened a new approach for efficient delivery of antitumor toxins with minimal exposure to normal cells. Several peptide sequences are known to have the ability to target tumors, for instance NGR motif which home specifically in solid tumors and …
One Rhizome, Two Unstoppable Blossoms: Environmental Communication And Ecological Rhetoric, Kevin James Ells
One Rhizome, Two Unstoppable Blossoms: Environmental Communication And Ecological Rhetoric, Kevin James Ells
LSU Doctoral Dissertations
This dissertation will contribute to the project of explaining what environmental communication studies may offer theoretically to an understanding of communication and rhetoric in general, investigate a complex problem in rhetoric from a variety of methodological approaches, offer examples of rhetorical criticism relevant to environmental communication researchers, and delve into certain salient aspects of ecological rhetoric (defined herein as rhetoric from an ecological perspective). The hypothesis of this doctoral thesis is twofold: 1) studying environmental communication can illuminate much about communication and rhetoric in general, and 2) ecological rhetoric has considerable persuasive potential in itself for reasons that can be …
"I Will Learn You Something If You Listen To This Song": Southern Women Writers' Representations Of Music In Fiction, Courtney George
"I Will Learn You Something If You Listen To This Song": Southern Women Writers' Representations Of Music In Fiction, Courtney George
LSU Doctoral Dissertations
This dissertation offers a rhetorical analysis of the formation of women’s memory, history, and communities in intersections of musical and literary expression in the American South, a region graced with a vital but underexamined tradition of female musicianship. Recent scholars have deconstructed the imagined narrative of southern culture as static, patriarchal, and white to uncover alternative stories and cultures that exist outside of canonical literature. This project significantly expands current understandings of these conflicting narratives by investigating how women writers recall, reclaim, and re-envision women’s roles in southern music to challenge, comply, and/or identify with women’s prescribed place in the …
The Perils And Empowerments Of Mountain Literacies: Reading Loss And Shifting Identities In Appalachian Memoirs And Novels, Erica Abrams Locklear
The Perils And Empowerments Of Mountain Literacies: Reading Loss And Shifting Identities In Appalachian Memoirs And Novels, Erica Abrams Locklear
LSU Doctoral Dissertations
This dissertation analyzes the literary portrayal of literacy events in memoirs and novels written by Appalachian women during the twentieth and twenty-first centuries. Drawing from contemporary literacy scholarship, my project engages several definitions of the term "literacy," including theories defining it as a technical skill, a social act, cultural knowledge, or a potent form of ideological power. In a region historically (and often inaccurately) stigmatized as illiterate, "literacy" is a loaded term, a concept doubly associated with cultural pride and with cultural loss. By applying literacy theories to Appalachian literature, I analyze the identity conflicts literacy attainment causes for several …
The Rhetorical Myth Of The Athlete As A Moral Hero: The Implications Of Steroids In Sport And The Threatened Myth, Karen L. Hartman
The Rhetorical Myth Of The Athlete As A Moral Hero: The Implications Of Steroids In Sport And The Threatened Myth, Karen L. Hartman
LSU Doctoral Dissertations
This research analyzes changes in the rhetoric of a sustaining myth in order to better assess what happens when a myth is threatened. By examining American sport and its current struggle to withstand the widespread use of steroids, the author investigates how public discourse about the scandal turns athletes from mythical heroes to cheaters. The author begins by explicating the rhetorical construction of the athlete as a moral hero in America and how this myth is perpetuated today. The author then examines how steroids threaten the myth of the moral athlete and uses Major League Baseball as a case study …
Disciplinary Differences In Preferred Research Methods: A Comparison Of Groups In The Biglan Classification Scheme, Mark A. Alise
Disciplinary Differences In Preferred Research Methods: A Comparison Of Groups In The Biglan Classification Scheme, Mark A. Alise
LSU Doctoral Dissertations
The Biglan system of classifying disciplines in groups based on similarities and differences in their subject matter has been validated in numerous empirical studies. The present study sought to expand that validation by comparing two Biglan groups that include disciplines representing the social and behavioral sciences. As a unique point of comparison, preferred research methods were contrasted between Psychology and Sociology forming one group of pure disciplines and Education and Nursing forming another group of applied disciplines. A code sheet was developed to categorize the various components of published research, distinguishing at the most basic level quantitative, qualitative, and mixed …
Processes And/Of Performance: Difference, Memory, And Experimentation, Benjamin Daniel Powell
Processes And/Of Performance: Difference, Memory, And Experimentation, Benjamin Daniel Powell
LSU Doctoral Dissertations
This study enacts performance analyses by combining experimental and avant-garde performance practices of artists or art movements such as John Cage, Jerzy Grotowski, Dadaism, and Eugenio Barba with the differential philosophies of Jacques Derrida and Gilles Deleuze. By focusing on the ways that performance practice informs understandings of “the ghost” and différance in Derrida’s theories, and processes of production and experimentation in Deleuze’s, this study examines performance as a process of negotiating practice and theory that continues to produce rather than disappear. To reinforce the productive capacity of performance, this study looks at three different sites and the processes at …
The Songs Of Black (Women) Folk: Music, Politics, And Everyday Living, Rasheedah Quiett Jenkins
The Songs Of Black (Women) Folk: Music, Politics, And Everyday Living, Rasheedah Quiett Jenkins
LSU Doctoral Dissertations
The field of folklore in general, but specifically Africana folklore studies can be enriched by greater analyses of Black female contributions. In this study, I position folk music as the primary interest and chosen location to acknowledge Black women’s participation from beyond the margins. My inquiry reveals folk music as a lens into the myriad ways in which Black women have translated vernacular traditions into a means to deconstruct the master narrative as well as interrogate racist patriarchy. Specifically, this study examines how Nina Simone, Tracy Chapman, and Lauryn Hill have appropriated the folk aesthetic as a vehicle for social …
Characterization And Comparison Of Cell Frequency, Growth, And Multipotential Differentiation Of Adult Mesenchymal Stromal Cells Derived From Equine Bone Marrow And Adipose Tissue, Martin Andreas Vidal
Characterization And Comparison Of Cell Frequency, Growth, And Multipotential Differentiation Of Adult Mesenchymal Stromal Cells Derived From Equine Bone Marrow And Adipose Tissue, Martin Andreas Vidal
LSU Doctoral Dissertations
Equine bone marrow-derived mesenchymal stromal cells (MSCs) and adipose tissue-derived stromal cells (ASCs) were compared for frequency within their respective tissues, cell doubling characteristics and differentiation multipotential in culture based on histochemical staining and compositional analysis. Equine MSCs and ASCs from young adult horses were harvested and isolated from sternal bone marrow and supragluteal subcutaneous adipose tissue, respectively, and grown up to passage 10 (P10) to determine cell doubling characteristics. Limit dilution assays were performed on primary and passaged (P2, P4) MSCs and ASCs to determine the frequency of colony forming units with a fibroblastic phenotype (CFU-F), and the frequency …