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Articles 61 - 90 of 290
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Pulmonary Embolism And Increased Levels Of D-Dimer In Patients With Coronavirus Disease, D. O. Griffin, A. Jensen, M. Khan, J. Chin, K. Chin, J. Saad, R. Parnell, C. Awwad, D. Patel
Pulmonary Embolism And Increased Levels Of D-Dimer In Patients With Coronavirus Disease, D. O. Griffin, A. Jensen, M. Khan, J. Chin, K. Chin, J. Saad, R. Parnell, C. Awwad, D. Patel
Journal Articles
No abstract provided.
Rapid Emergence Of Sars-Cov-2 In The Greater New York Metropolitan Area: Geolocation, Demographics, Positivity Rates, And Hospitalization For 46,793 Persons Tested By Northwell Health., S. B. Reichberg, P. P. Mitra, A. Haghamad, G. Ramrattan, J. M. Crawford, G. J. Berry, K. W. Davidson, A. Drach, S. Duong, S. Juretschko, N. I. Maria, Y. Yang, Y. C. Ziemba, Northwell Covid-19 Research Consortium
Rapid Emergence Of Sars-Cov-2 In The Greater New York Metropolitan Area: Geolocation, Demographics, Positivity Rates, And Hospitalization For 46,793 Persons Tested By Northwell Health., S. B. Reichberg, P. P. Mitra, A. Haghamad, G. Ramrattan, J. M. Crawford, G. J. Berry, K. W. Davidson, A. Drach, S. Duong, S. Juretschko, N. I. Maria, Y. Yang, Y. C. Ziemba, Northwell Covid-19 Research Consortium
Journal Articles
BACKGROUND:In March 2020, the greater New York metropolitan area became an epicenter for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The initial evolution of case incidence has not been well characterized. METHODS:Northwell Health Laboratories tested 46,793 persons for SARS-CoV-2 from March 4 through April 10. The primary outcome measure was a positive reverse-transcription-polymerase-chain-reaction (RT-PCR) test for SARS-CoV-2. The secondary outcomes included patient age, sex, and race if stated; dates the specimen was obtained and the test result; clinical practice site sources; geo-location of patient residence; and hospitalization. RESULTS:From March 8 through April 10, a total of 26,735 of 46,793 …
Are Children With Sars-Cov-2 Infection At High Risk For Thrombosis? Viscoelastic Testing And Coagulation Profiles In A Case Series Of Pediatric Patients, M. Al-Ghafry, B. Aygun, A. Appiah-Kubi, A. Vlachos, G. Ostovar, C. Capone, T. Sweberg, N. Palumbo, P. Goenka, L. L. Wolfe, J. M. Lipton, S. S. Acharya
Are Children With Sars-Cov-2 Infection At High Risk For Thrombosis? Viscoelastic Testing And Coagulation Profiles In A Case Series Of Pediatric Patients, M. Al-Ghafry, B. Aygun, A. Appiah-Kubi, A. Vlachos, G. Ostovar, C. Capone, T. Sweberg, N. Palumbo, P. Goenka, L. L. Wolfe, J. M. Lipton, S. S. Acharya
Journal Articles
© 2020 Wiley Periodicals LLC The coagulopathy of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is well documented in adults, with increases in D-dimer and prothrombin time found to be strong predictors of mortality, and anticoagulation shown to decrease this mortality. Viscoelastic parameters such as elevations in maximum clot firmness (MCF) on rotational thromboelastometry (ROTEM) have correlated with a hypercoagulable state in adults with SARS-CoV-2. We report our experience in children infected with SARS-CoV-2, with noted elevations in D-dimer and MCF on ROTEM (indicating hypercoagulability). Exploration of viscoelastic testing to provide additional laboratory-based evidence for pediatric-specific risk assessment …
Comparative Survival Analysis Of Immunomodulatory Therapy For Coronavirus Disease 2019 Cytokine Storm., S. Narain, D. G. Stefanov, A. S. Chau, A. G. Weber, G. Marder, B. Kaplan, P. Malhotra, O. Bloom, A. Liu, M. M. Lesser, N. Hajizadeh, Northwell Covid-19 Research Consortium
Comparative Survival Analysis Of Immunomodulatory Therapy For Coronavirus Disease 2019 Cytokine Storm., S. Narain, D. G. Stefanov, A. S. Chau, A. G. Weber, G. Marder, B. Kaplan, P. Malhotra, O. Bloom, A. Liu, M. M. Lesser, N. Hajizadeh, Northwell Covid-19 Research Consortium
Journal Articles
BACKGROUND:Cytokine storm is a marker of coronavirus disease 2019 (COVID-19) illness severity and increased mortality. Immunomodulatory treatments have been repurposed to improve mortality outcomes. RESEARCH QUESTION:Do immunomodulatory therapies improve survival in patients with COVID-19 cytokine storm (CCS)? STUDY DESIGN AND METHODS:We conducted a retrospective analysis of electronic health records across the Northwell Health system. COVID-19 patients hospitalized between March 1, 2020, and April 24, 2020, were included. CCS was defined by inflammatory markers: ferritin, > 700 ng/mL; C-reactive protein (CRP), > 30 mg/dL; or lactate dehydrogenase (LDH), > 300 U/L. Patients were subdivided into six groups: no immunomodulatory treatment (standard of care) and …
Covid-19 And Cancer Patients., R Patel, J Park, A Shah, Mw Saif
Covid-19 And Cancer Patients., R Patel, J Park, A Shah, Mw Saif
Journal Articles
No abstract provided.
An Unusual Case Of Moraxella Osleonsis Bacteremia In An Immunocompetent Patient With Sars-Cov-2 Infection., B. C. Veerabathini, K. Manthani, S. Gandhi
An Unusual Case Of Moraxella Osleonsis Bacteremia In An Immunocompetent Patient With Sars-Cov-2 Infection., B. C. Veerabathini, K. Manthani, S. Gandhi
Journal Articles
Moraxella osleonsis (M.osleonsis ) is an organism that rarely presents with bacteremia in immunocompetent patients. We report a case of an immunocompetent 59-year-old male with a recent SARS-CoV-2 infection that developed M. osleonsis bacteremia. We believe that SARS-CoV-2 infection may have played a role in developing M. osleonsis bacteremia in this patient and may be one of the first reported cases of such bacteremia in a COVID-19 patient.
Central Nervous System Complications Associated With Sars-Cov-2 Infection: Integrative Concepts Of Pathophysiology And Case Reports, S. Najjar, A. Najjar, D. J. Chong, B. K. Pramanik, C. Kirsch, R. Kuzniecky, S. Pacia, S. Azhar
Central Nervous System Complications Associated With Sars-Cov-2 Infection: Integrative Concepts Of Pathophysiology And Case Reports, S. Najjar, A. Najjar, D. J. Chong, B. K. Pramanik, C. Kirsch, R. Kuzniecky, S. Pacia, S. Azhar
Journal Articles
No abstract provided.
Covid-19 As A Possible Cause Of Functional Exhaustion Of Cd4 And Cd8 T-Cells And Persistent Cause Of Methicillin-Sensitive Staphylococcus Aureus Bacteremia., I. Choudhury, H. Han, K. Manthani, S. Gandhi, R. Dabhi
Covid-19 As A Possible Cause Of Functional Exhaustion Of Cd4 And Cd8 T-Cells And Persistent Cause Of Methicillin-Sensitive Staphylococcus Aureus Bacteremia., I. Choudhury, H. Han, K. Manthani, S. Gandhi, R. Dabhi
Journal Articles
We report a case of a 73-year-old male with a history of diabetes mellitus, osteomyelitis, methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia who recently completed an extended intravenous course of cefazolin eight days back, and presented with MSSA bacteremia complicated by epidural abscess, endocarditis, and aortic root abscess. Meanwhile, the patient was tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcription-polymerase chain reaction (RT-PCR). Even with aggressive antibiotic treatment, the patient remained bacteremic and developed endocarditis with a worsening aortic root abscess. We suspect coronavirus disease 2019 (COVID-19) as a cause for the infectious paradox and will discuss …
Covid-19 Clinical Research., J. Chi, D. Chitty, M. Lee, N. Hakim, S. Lakhani, L. Rajdev, X. Zhu, M. W. Saif
Covid-19 Clinical Research., J. Chi, D. Chitty, M. Lee, N. Hakim, S. Lakhani, L. Rajdev, X. Zhu, M. W. Saif
Journal Articles
Introduction:While the global COVID-19 pandemic has challenged the entire humanity and health systems, it also triggered researchers to urgently perform clinical trials to assess the safety and efficacy of many agents and modalities to combat COVID-19. As of April 22, over 650 clinical studies have been registered both in USA and internationally. Results from these studies are also coming at a brisk pace in this unprecedented emergency. Areas covered:We searched the NCI website and Medline and summarize various national and international clinical trials and summarize few of the pivotal ones in this paper, including those specific to oncology population. Two …
Development Of A New Multiplex Real-Time Rt-Pcr Assay For Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Detection., W. Zhen, G. J. Berry
Development Of A New Multiplex Real-Time Rt-Pcr Assay For Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Detection., W. Zhen, G. J. Berry
Journal Articles
This research describes the development of a new multiplex real-time RT-PCR test for detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with primers designed to amplify a 108 bp target on the spike surface glycoprotein (S gene) and a hydrolysis TaqMan probe designed to specifically detect SARS-CoV-2. The limit of detection (LOD) and clinical performance of this new assay were evaluated. A LOD study with inactivated virus exhibited performance equal to the modified CDC assay, with a final LOD of 1301 ± 13 genome equivalents/mL for the Northwell Health Laboratories laboratory-developed test (NWHL LDT) versus 1249 ± 14 genome …
Covid-19 Presenting As Acute Hepatitis, P. Wander, M. Epstein, D. Bernstein
Covid-19 Presenting As Acute Hepatitis, P. Wander, M. Epstein, D. Bernstein
Journal Articles
No abstract provided.
A Case Of Vancomycin-Induced Immune Thrombocytopenia., K. N. Macdougall, S. Parylo, A. Sokoloff
A Case Of Vancomycin-Induced Immune Thrombocytopenia., K. N. Macdougall, S. Parylo, A. Sokoloff
Journal Articles
Vancomycin-induced immune thrombocytopenia (ITP) is a rare, potentially life-threatening complication from an antibiotic frequently used in medical practice. We report a case of an 81-year-old male with recent removal of an infected right knee prosthesis and insertion of an articulating antibiotic spacer, presenting from rehabilitation for severe thrombocytopenia (1 X 103/µL). The patient's thrombocytopenia was initially falsely attributed to rifampin-induced ITP, a much more common cause of drug-induced thrombocytopenia. Only later, after a second precipitous drop in platelet count, vancomycin was correctly identified as the culprit. The patient's serum was tested for drug-dependent platelet antibodies with and without vancomycin. A …
A Case Of Listeria Monocytogenes Meningitis Complicated By Hydrocephalus And Intraventricular Hemorrhage: A Review Of Treatment Options And Outcomes, S. Gerstein, P. Gautam-Goyal, S. Goyal
A Case Of Listeria Monocytogenes Meningitis Complicated By Hydrocephalus And Intraventricular Hemorrhage: A Review Of Treatment Options And Outcomes, S. Gerstein, P. Gautam-Goyal, S. Goyal
Journal Articles
© 2020 The Authors Listeria monocytogenes is a gram-positive bacillus known to cause various human infections including central nervous system infections. The most common central nervous system manifestations are meningitis and rhomboencephalitis, however rare complications including hydrocephalus and intracerebral hemorrhage can occur and are associated with increased mortality and incidence of lasting neurologic sequelae. The mortality ranges from 17 % to greater than 30 % in patients with neurological involvement [1–3]. Various case reports have studied the differing treatment approaches and outcomes of patients who experienced these complications, and there is still no consensus on optimal treatment approaches. In this …
New Paradigms Of Extended Thromboprophylaxis In Medically Ill Patients, K. Macdougall, A. C. Spyropoulos
New Paradigms Of Extended Thromboprophylaxis In Medically Ill Patients, K. Macdougall, A. C. Spyropoulos
Journal Articles
No abstract provided.
Scientific And Standardization Committee Communication: Clinical Guidance On The Diagnosis, Prevention And Treatment Of Venous Thromboembolism In Hospitalized Patients With Covid-19., A. C. Spyropoulos, J. H. Levy, W. Ageno, J. M. Connors, B. J. Hunt, T. Iba, M. Levi, C. M. Samama, D. Giannis, +2 Additional Authors
Scientific And Standardization Committee Communication: Clinical Guidance On The Diagnosis, Prevention And Treatment Of Venous Thromboembolism In Hospitalized Patients With Covid-19., A. C. Spyropoulos, J. H. Levy, W. Ageno, J. M. Connors, B. J. Hunt, T. Iba, M. Levi, C. M. Samama, D. Giannis, +2 Additional Authors
Journal Articles
The novel coronavirus disease of 2019 (COVID-19) pandemic, as declared by the World Health Organization, is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). Cardiovascular disease and, in particular, venous thromboembolism (VTE) has emerged as an important consideration in the management of hospitalized patients with COVID-19. The diagnosis of VTE using standardized objective testing is problematic in these patients, given the risk of infecting non-COVID-19 hospitalized patients and hospital personnel, coupled with the usual challenges of performing diagnostic testing in critically-ill patients. Early reports suggest a high incidence of VTE in hospitalized COVID-19 patients, particularly those with severe …
Comparison Of Four Molecular In Vitro Diagnostic Assays For The Detection Of Sars-Cov-2 In Nasopharyngeal Specimens., W Zhen, R Manji, E Smith, Gj Berry
Comparison Of Four Molecular In Vitro Diagnostic Assays For The Detection Of Sars-Cov-2 In Nasopharyngeal Specimens., W Zhen, R Manji, E Smith, Gj Berry
Journal Articles
No abstract provided.
Covid-19 Presenting As Stroke, A. Avula, K. Nalleballe, N. Narula, S. Sapozhnikov, V. Dandu, S. Toom, A. Glaser, D. Elsayegh
Covid-19 Presenting As Stroke, A. Avula, K. Nalleballe, N. Narula, S. Sapozhnikov, V. Dandu, S. Toom, A. Glaser, D. Elsayegh
Journal Articles
© 2020 Elsevier Inc. Objective: Acute stroke remains a medical emergency even during the COVID-19 pandemic. Most patients with COVID-19 infection present with constitutional and respiratory symptoms; while others present with atypical gastrointestinal, cardiovascular, or neurological manifestations. Here we present a series of four patients with COVID-19 that presented with acute stroke. Methods: We searched the hospital databases for patients that presented with acute stroke and concomitant features of suspected COVID-19 infection. All patients who had radiographic evidence of stroke and PCR-confirmed COVID-19 infection were included in the study. Patients admitted to the hospital with PCR- confirmed COVID-19 disease whose …
Arterial Thromboembolic Complications In Covid-19 In Low-Risk Patients Despite Prophylaxis, D. O. Griffin, A. Jensen, M. Khan, J. Chin, K. Chin, R. Parnell, C. Awwad, D. Patel
Arterial Thromboembolic Complications In Covid-19 In Low-Risk Patients Despite Prophylaxis, D. O. Griffin, A. Jensen, M. Khan, J. Chin, K. Chin, R. Parnell, C. Awwad, D. Patel
Journal Articles
No abstract provided.
European Heart Rhythm Association (Ehra) International Consensus Document On How To Prevent, Diagnose, And Treat Cardiac Implantable Electronic Device Infections - Endorsed By The Heart Rhythm Society (Hrs), The Asia Pacific Heart Rhythm Society (Aphrs), The Latin American Heart Rhythm Society (Lahrs), International Society For Cardiovascular Infectious Diseases (Iscvid) And The European Society Of Clinical Microbiology And Infectious Diseases (Escmid) In Collaboration With The European Association For Cardio-Thoracic Surgery (Eacts), C. Blomström-Lundqvist, V. Traykov, P. A. Erba, H. Burri, J. C. Nielsen, M. G. Bongiorni, J. Poole, G. Boriani, L. M. Epstein, E. Mangoni, +10 Additional Authors
European Heart Rhythm Association (Ehra) International Consensus Document On How To Prevent, Diagnose, And Treat Cardiac Implantable Electronic Device Infections - Endorsed By The Heart Rhythm Society (Hrs), The Asia Pacific Heart Rhythm Society (Aphrs), The Latin American Heart Rhythm Society (Lahrs), International Society For Cardiovascular Infectious Diseases (Iscvid) And The European Society Of Clinical Microbiology And Infectious Diseases (Escmid) In Collaboration With The European Association For Cardio-Thoracic Surgery (Eacts), C. Blomström-Lundqvist, V. Traykov, P. A. Erba, H. Burri, J. C. Nielsen, M. G. Bongiorni, J. Poole, G. Boriani, L. M. Epstein, E. Mangoni, +10 Additional Authors
Journal Articles
© 2019 The Author(s). Published by Oxford University Press on behalf of the European Society of Cardiology. Pacemakers, implantable cardiac defibrillators, and cardiac resynchronization therapy devices are potentially life-saving treatments for a number of cardiac conditions, but are not without risk. Most concerning is the risk of a cardiac implantable electronic device (CIED) infection, which is associated with significant morbidity, increased hospitalizations, reduced survival, and increased healthcare costs. Recommended preventive strategies such as administration of intravenous antibiotics before implantation are well recognized. Uncertainties have remained about the role of various preventive, diagnostic, and treatment measures such as skin antiseptics, pocket …
Hrs/Ehra/Aphrs/Lahrs/Acc/Aha Worldwide Practice Update For Telehealth And Arrhythmia Monitoring During And After A Pandemic., N. Varma, N. F. Marrouche, L. Aguinaga, C. M. Albert, E. Arbelo, J. Choi, M. K. Chung, G. Conte, L. M. Epstein, P. D. Varosy, +13 Additional Authors
Hrs/Ehra/Aphrs/Lahrs/Acc/Aha Worldwide Practice Update For Telehealth And Arrhythmia Monitoring During And After A Pandemic., N. Varma, N. F. Marrouche, L. Aguinaga, C. M. Albert, E. Arbelo, J. Choi, M. K. Chung, G. Conte, L. M. Epstein, P. D. Varosy, +13 Additional Authors
Journal Articles
No abstract provided.
Covid-19 In Children: More Than Meets The Eye, Sh F. Hagmann
Covid-19 In Children: More Than Meets The Eye, Sh F. Hagmann
Journal Articles
No abstract provided.
Cll Intraclonal Fractions Exhibit Established And Recently Acquired Patterns Of Dna Methylation, B. A. Bartholdy, X. Wang, X. Yan, M. Pascual, M. Fan, J. Barrientos, S. L. Allen, K. R. Rai, N. Chiorazzi, S. Roa, +2 Additional Authors
Cll Intraclonal Fractions Exhibit Established And Recently Acquired Patterns Of Dna Methylation, B. A. Bartholdy, X. Wang, X. Yan, M. Pascual, M. Fan, J. Barrientos, S. L. Allen, K. R. Rai, N. Chiorazzi, S. Roa, +2 Additional Authors
Journal Articles
No abstract provided.
Elevated Liver Biochemistries In Hospitalized Chinese Patients With Severe Covid-19: Systematic Review And Meta-Analysis., A. J. Kovalic, G. Huang, P. J. Thuluvath, S. K. Satapathy
Elevated Liver Biochemistries In Hospitalized Chinese Patients With Severe Covid-19: Systematic Review And Meta-Analysis., A. J. Kovalic, G. Huang, P. J. Thuluvath, S. K. Satapathy
Journal Articles
BACKGROUND & AIMS:Several recent studies have reported an abnormal liver chemistry profile among patients with coronavirus disease 2019 (COVID-19), although its clinical significance remains unknown. APPROACH & RESULTS:This novel systematic review and meta-analysis identified six studies of 586 patients delineating liver chemistries among patients with severe/critical illness versus mild cases of COVID-19 infection. Patients with severe/critical illness with COVID-19 infection have increased prevalence of coronary artery disease (CAD), cerebrovascular disease, and chronic obstructive pulmonary disease (COPD) as compared to mild cases. A significant association between severe/critical COVID-19 infections with elevations in aspartate aminotransferase (AST) (pooled mean difference [MD], 11.70 U/L; …
General And Intensive Care Outcomes For Hospitalized Patients With Solid Organ Transplants With Covid-19, F. Mastroianni, D. E. Leisman, G. Fisler, M. Narasimhan
General And Intensive Care Outcomes For Hospitalized Patients With Solid Organ Transplants With Covid-19, F. Mastroianni, D. E. Leisman, G. Fisler, M. Narasimhan
Journal Articles
© The Author(s) 2020. Purpose: COVID-19 has been associated with a dysregulated inflammatory response. Patients who have received solid-organ transplants are more susceptible to infections in general due to the use of immunosuppressants. We investigated factors associated with mechanical ventilation and outcomes in solid-organ transplant recipients with COVID-19. Materials and Methods: We conducted a retrospective cohort study of all solid-organ transplant recipients admitted with a diagnosis of COVID-19 in our 23-hospital health system over a 1-month period. Descriptive statistics were used to describe hospital course and laboratory results and bivariate comparisons were performed on variables to determine differences. Results: Twenty-two …
Use Of Tetanus Toxoid, Reduced Diphtheria Toxoid, And Acellular Pertussis Vaccines: Updated Recommendations Of The Advisory Committee On Immunization Practices - United States, 2019, F. P. Havers, P. L. Moro, P. Hunter, S. Hariri, H. Bernstein
Use Of Tetanus Toxoid, Reduced Diphtheria Toxoid, And Acellular Pertussis Vaccines: Updated Recommendations Of The Advisory Committee On Immunization Practices - United States, 2019, F. P. Havers, P. L. Moro, P. Hunter, S. Hariri, H. Bernstein
Journal Articles
No abstract provided.
Molecular Testing For Acute Respiratory Tract Infections: Clinical And Diagnostic Recommendations From The Idsa's Diagnostics Committee., K. E. Hanson, M. M. Azar, R. Banerjee, A. Chou, R. C. Colgrove, C. C. Ginocchio, M. K. Hayden, M. Holodiny, S. Jain, Diagnostics Committee Of The Infectious Diseases S, +4 Additional Authors
Molecular Testing For Acute Respiratory Tract Infections: Clinical And Diagnostic Recommendations From The Idsa's Diagnostics Committee., K. E. Hanson, M. M. Azar, R. Banerjee, A. Chou, R. C. Colgrove, C. C. Ginocchio, M. K. Hayden, M. Holodiny, S. Jain, Diagnostics Committee Of The Infectious Diseases S, +4 Additional Authors
Journal Articles
The clinical signs and symptoms of acute respiratory tract infections (RTIs) are not pathogen specific. Highly sensitive and specific nucleic acid amplification tests have become the diagnostic reference standard for viruses and translation of bacterial assays from basic research to routine clinical practice represents an exciting advance in respiratory medicine. Most recently, molecular diagnostics have played an essential role in the global health response to the novel coronavirus pandemic. How best to use newer molecular tests for RTI in combination with clinical judNorthwell Healthnt and traditional methods can be bewildering given the plethora of available assays and rapidly evolving technologies. …
Obesity And Sting1 Genotype Associate With 23-Valent Pneumococcal Vaccination Efficacy, M. Sebastian, C. J. Hsiao, H. S. Futch, R. S. Eisinger, L. Dumeny, S. Patel, M. Gobena, D. S. Katikaneni, L. Spiryda, M. L. Brantly, +4 Additional Authors
Obesity And Sting1 Genotype Associate With 23-Valent Pneumococcal Vaccination Efficacy, M. Sebastian, C. J. Hsiao, H. S. Futch, R. S. Eisinger, L. Dumeny, S. Patel, M. Gobena, D. S. Katikaneni, L. Spiryda, M. L. Brantly, +4 Additional Authors
Journal Articles
© 2020, Sebastian etal. BACKGROUND. Obesity has been associated with attenuated vaccine responses and an increased risk of contracting pneumococcal pneumonia, but no study to our knowledge has assessed the impact of obesity and genetics on 23-valent pneumococcal vaccine (PPSV23) efficacy. We assessed the relationship of obesity (primary analysis) and stimulator of interferon genes (STING1) genotype (secondary analysis) on PPSV23 efficacy. METHODS. Nonobese (BMI 22-25 kg/m2) and obese participants (BMI ≥30 kg/m2) were given a single dose of PPSV23. Blood was drawn immediately prior to and 4-6 weeks after vaccination. Serum samples were used to assess PPSV23-specific antibodies. STING1 genotypes …
A Modified Delphi Study To Prioritize Content For A Simulation-Based Pediatric Curriculum For Emergency Medicine Residency Training Programs, J. Mitzman, I. Bank, R. A. Burns, M. C. Nguyen, P. Zaveri, M. J. Falk, M. Madhok, A. Dietrich, F. M. Bullaro, M. Auerbach, +9 Additional Authors
A Modified Delphi Study To Prioritize Content For A Simulation-Based Pediatric Curriculum For Emergency Medicine Residency Training Programs, J. Mitzman, I. Bank, R. A. Burns, M. C. Nguyen, P. Zaveri, M. J. Falk, M. Madhok, A. Dietrich, F. M. Bullaro, M. Auerbach, +9 Additional Authors
Journal Articles
© 2019 by the Society for Academic Emergency Medicine Objectives: Pediatric training is an essential component of emergency medicine (EM) residency. The heterogeneity of pediatric experiences poses a significant challenge to training programs. A national simulation curriculum can assist in providing a standardized foundation of pediatric training experience to all EM trainees. Previously, a consensus-derived set of content for a pediatric curriculum for EM was published. This study aimed to prioritize that content to establish a pediatric simulation-based curriculum for all EM residency programs. Methods: Seventy-three participants were recruited to participate in a three-round modified Delphi project from 10 stakeholder …
Brucella Exposure Risk Events In 10 Clinical Laboratories, New York City, Usa, 2015 To 2017, J. Ackelsberg, A. Liddicoat, T. Burke, W. A. Szymczak, M. H. Levi, B. Ostrowsky, E. A. Mitchell, W. Lowe, R. Khare, M. Layton, +34 Additional Authors
Brucella Exposure Risk Events In 10 Clinical Laboratories, New York City, Usa, 2015 To 2017, J. Ackelsberg, A. Liddicoat, T. Burke, W. A. Szymczak, M. H. Levi, B. Ostrowsky, E. A. Mitchell, W. Lowe, R. Khare, M. Layton, +34 Additional Authors
Journal Articles
Copyright © 2020 American Society for Microbiology. All Rights Reserved. From 2015 to 2017, 11 confirmed brucellosis cases were reported in New York City, leading to 10 Brucella exposure risk events (Brucella events) in 7 clinical laboratories (CLs). Most patients had traveled to countries where brucellosis is endemic and presented with histories and findings consistent with brucellosis. CLs were not notified that specimens might yield a hazardous organism, as the clinicians did not consider brucellosis until they were notified that bacteremia with Brucella was suspected. In 3 Brucella events, the CLs did not suspect that slow-growing, small Gram-negative bacteria might …
Soluble Urokinase Plasminogen Activator Receptor (Supar) Levels Predict Damage Accrual In Patients With Recent-Onset Systemic Lupus Erythematosus, H. Enocsson, L. Wirestam, C. Dahle, L. Padyukov, A. Jönsen, M. B. Urowitz, D. D. Gladman, C. Aranow, M. Mackay, C. Sjöwall, +36 Additional Authors
Soluble Urokinase Plasminogen Activator Receptor (Supar) Levels Predict Damage Accrual In Patients With Recent-Onset Systemic Lupus Erythematosus, H. Enocsson, L. Wirestam, C. Dahle, L. Padyukov, A. Jönsen, M. B. Urowitz, D. D. Gladman, C. Aranow, M. Mackay, C. Sjöwall, +36 Additional Authors
Journal Articles
© 2019 The Authors Objective: The soluble urokinase plasminogen activator receptor (suPAR) has potential as a prognosis and severity biomarker in several inflammatory and infectious diseases. In a previous cross-sectional study, suPAR levels were shown to reflect damage accrual in cases of systemic lupus erythematosus (SLE). Herein, we evaluated suPAR as a predictor of future organ damage in recent-onset SLE. Methods: Included were 344 patients from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort who met the 1997 American College of Rheumatology classification criteria with 5-years of follow-up data available. Baseline sera from patients and age- and sex-matched controls …