Digital Commons Network^™

Microsolvation Effects Of 1,1-Dimethyl-Biguanide (Metformin), Jasmine L. Sanders

Honors Theses

The microsolvation of a 1,1-dimethyl-biguanide hydrochloride molecule in the presence of water molecules illustrates the initial interactions between the common drug metformin and water. This explicit water-solvation approach employs coupled-cluster theory with an explicit-correlation F12 correction and the cc-pVTZ-F12 basis set to determine the optimalgeometry of the molecule and to observe intermolecular interaction energies. 1,1-dimethyl-biguanide hydrochloride (an antidiabetic agent, metformin) is constantly in contact with water molecules in the human body, where it reduces intestinal glucose absorption, lowers hepatic glucose sensitivity, and improves overall insulin sensitivity to lower blood-glucose concentration. The B3LYP method with an aug-cc-pVTZ basis set is used …

Wild Robots: Humans, Wilderness, And Technology In Becky Chambers’ Monk And Robot Series, Melissa Moore

Honors Theses

As technology advances and the environment deteriorates, the way people view the relationships between technology, wilderness, and humans becomes essential for society to move forward. To investigate perceptions about technology’s place in an environmentally conscious society, this project examines manifestations of wilderness/wildness and technology in Becky Chambers’ Monk and Robot series through the lens of ecocriticism. Using Timothy Morton's concept of the ecological thought as a framework for analysis, the circumstances present in the novel suggest that the triangle separating humans, wilderness, and technology has actually collapsed, replaced by an enmeshment of technology, wilderness, and humanity.

Design, Synthesis And Biological Activities Of N-Substituted Phthalimide Derivative, Beaula Mangundah

Honors Theses

Phthalimides are a group of compounds among bicyclic non-aromatic nitrogen heterocycles that have gained recognition for their bioactivity across various fields, notably anti-cancer, anti-microbial, anti-oxidant, and anti-inflammatory. This study discusses the synthesis of a novel phthalimide derivative and provides an analysis of its biological activity. It was conducted through a Boric acid Imide synthesis and yielded a successful derivative using hexylamine. The product was evaluated in vitro for antimicrobial, anticoagulant, and anti-inflammatory properties using Kirby-Bauer disk diffusion, clotting time, hemolysis inhibition, and protein denaturation assays. It showed mild anticoagulant and anti-inflammatory activity.

Effects Of Pamam Dendrimer Size On Antimicrobial Activity For Acne Treatment, Elise M. Inae

Honors Theses

This study investigated the antimicrobial activity of G1, G2, and G3-Hex-NH2 polyamidoamine (PAMAM) dendrimers with an emphasis on how dendrimer size influenced their efficacy against C. acnes and S. epidermidis. Dendrimers are nano-sized, radially symmetric polymers composed of highly branched units that extend out from a central core. Dendrimers are known to exhibit antimicrobial activity against Gram-negative bacteria by disrupting the lipid bilayer and causing membrane damage. This study explored their effect on a different group of microorganisms–Gram-positive skin flora. Kirby-Bauer disk diffusion tests were performed to evaluate minimum inhibitory concentrations for each dendrimer solution. All generations of PAMAM dendrimers …

Green Synthesis Of And Antimicrobial Susceptibility Testing Of (2z)-2-[(4-Fluorophenyl)Methylidene]-1-Benzofuran-3-One, Rod Albert C. Olofernes

Honors Theses

Antimicrobial resistance is a global health challenge, rendering once-effective antibiotics less potent or entirely ineffective. In response, there is increasing interest in developing antimicrobial agents through environmentally sustainable methods. In this study, a fluorinated aurone derivative, (2Z)-2-[(4-fluorophenyl)methylidene]-1-benzofuran-3-one, was synthesized using a green Knoevenagel condensation approach. Eco-friendly catalysts were employed to minimize environmental impact and avoid hazardous byproducts. Product formation was confirmed to avoid wasting resources. The compound was evaluated for antimicrobial properties using a Kirby-Bauer plate, but did not demonstrate consistent or significant antimicrobial activity, therefore lacking promise as a standalone antibiotic.

Effectiveness Of Dna Recovery Success From Porcine Metacarpals And Phalanges Submerged In Household Chemicals, Jessica Di Re

Honors Theses

This experiment evaluated the DNA recovery success from phalanges and metacarpals isolated from fleshed porcine feet that were soaked in different household cleaners and chemicals. Three sets of two porcine feet were submerged in Drano, method: All-Purpose Cleaner, and a 1:1 dilution of lemon juice to tap water, respectively. Another set of two porcine feet, assigned to the control group, was left unsubmerged. All four sets were left to decompose for 28 days. Pictures and weights were taken once a week for the duration, before the bones were isolated and powdered for extraction using the BTA Prepfiler Kit, followed by …

Intradistrict Inequality: Examining Educational Opportunity In Richmond Elementary Schools, Tara Sheehan

Honors Theses

Educational inequality in the U.S. is often discussed across district lines, but differences between schools within the same district are just as significant. This paper examines intradistrict disparities in Richmond Public Schools (RPS) by comparing William Fox Elementary and Broad Rock Elementary. Although both schools operate under the same district, they serve very different student populations and produce markedly different outcomes. William Fox serves mostly White and economically advantaged students, with higher test scores, lower absenteeism, fewer behavioral incidents, and access to a wide range of enrichment programs. Broad Rock, on the other hand, serves predominantly Hispanic and Black students, …

Art And Reentry: A Study On The Role Of Art Programs In The Reentry Of Formerly Incarcerated People, Angelina Paulus

Honors Theses

Arts programs are a well-established method of rehabilitation in prisons, yet limited research has examined the role of arts programs specifically during the post-incarceration reentry process. This qualitative study explores how participation in an arts-based reentry program shapes the emotional, social, and identity-related experience of formerly incarcerated individuals during reentry. Semi-structured interviews were conducted with five formerly incarcerated men who formerly participated in As We Emerge, a performance-based theater and monologue program offered through EMERGE Connecticut in New Haven, CT. Using inductive thematic analysis, three primary themes emerged: (1) processing emotions, (2) the development of social support and community connections, …

Understanding Parental Perceptions Of Truancy In Connecticut Youth: Identifying Risks And Prevention Strategies, Samantha Villa

Honors Theses

This research investigates Connecticut parents' perspectives on effective strategies for addressing truancy. By examining stakeholder attitudes and beliefs, the study aimed to understand the relationship between perceptions of responsibility for truancy prevention and support for punitive versus non-punitive intervention approaches. In light of the COVID-19 pandemic's impact on truancy rates, current legislation and interventions have proven inadequate. This study assessed Connecticut adults' recommendations for truancy policy reforms and explored the potential for community-based interventions to enhance family engagement and reduce reliance on court involvement and punitive sanctions. IBM SPSS was used to analyze an existing dataset from the Tow Youth …

Effects Of Proactive Interference On Adults With Adhd: A Sex-Based Study, Julia Switzer

Honors Theses

ADHD is a widespread phenomenon that affects individuals in a variety of ways. Many individuals exhibit strong proactive interference, in which past memories interfere with the memorization and recall of new information. One of the ways symptoms differ is through the biological sex of individuals, although differences in proactive interference have not been studied in relation to sex. This study hypothesized that women with ADHD are better at resisting proactive interference than males with ADHD. The study involved a digital activity in which a series of colored shapes was shown to participants, who identified whether the previously displayed shapes or …

The Dynamic Interplay Between Monovalent Salts And Ribosomal Protein S1 In Regulating Rna G-Quadruplex Structure, Chloe M. Martin

Honors Theses

Many remarkable discoveries, especially in the last decade, have shown scientists just how important RNA is. In this study, the secondary structure of RNA, G-Quadruplexes, is the topic of interest and how they are affected by salts and S1 protein. To obtain the S1 protein it was transformed from E. Coli using a bacterial plasmid. The S1 protein was then purified from the bacteria through the use of many purification methods. The monovalent cationic salts used were LiCl and KCl which have different ionic radii size that contributes to the stability of RNA G-Quadruplexes. This stability was observed and affected …

Effects Of Beach Renourishment On Sea Turtle Nesting Success, Caydence Pennington

Honors Theses

Beach geomorphology has a profound influence on nesting animals, particularly sea turtles, whose reproductive success depends on suitable sand conditions and stable shorelines. In many densely populated coastal regions, beach renourishment projects are implemented to combat erosion and protect infrastructure, yet these alterations can also affect sea turtle nesting ecology. This study evaluated the effects of beach renourishment on loggerhead sea turtle (Caretta caretta) nesting activity on Longboat Key, Florida, from 2021-2024. Nesting activity, hatch success, and depredation patterns were compared between nourished and reference beach zones to determine whether nourishment had an impact on these events. Nesting …

Chinese Intellectual Property Theft On United States Innovation In The Aerospace, Energy, And Pharmaceutical Economic Sectors Through Human Intelligence And Cyber Intelligence Collection, Preston Martz

Honors Theses

In cases of Chinese intellectual property theft on aerospace, energy, and pharmaceutical sectors in the United States, does Chinese intelligence collection favor HUMINT or CYBINT for collection? Sub questions also arise, including: to what extent does the amount of information collected vary by collection through HUMINT vs. CYBINT? Furthermore, does the sector where IP theft is used change the method of collection used? Finally, to what extend do case factors and outcomes affect the collection method used?

Effects Of Beach Morphology On Nesting Behavior And Success Of Loggerhead Sea Turtles (Caretta Caretta) In South Carolina, Reagan Rutkowski

Honors Theses

Loggerhead sea turtles (Caretta caretta) rely on sandy beach habitats for successful reproduction, yet nesting success is strongly influenced by physical beach features. This study examines the impact of beach morphology on nest survivorship across six nesting beaches in Horry and Georgetown counties, South Carolina. Three key hypotheses were tested: (1) nests placed at higher elevations exhibit greater survivorship, (2) nests located further from the recent high tide line experience higher survivorship, and (3) overall beach morphology influences nesting behavior and outcomes. Beach morphology variables—including elevation, slope, and nest-to-water distances—were measured at individual nest sites, while survivorship data …

Interdependence In Practice: U.S. Travel Advisories And Turkey’S Economic Resilience, Matthew Michael Mccall

Honors Theses

This study examines the U.S. Travel Advisory and its economic impact on foreign nations, with a focus on Turkey between 2016 and 2024. Grounded in the theories of functional and asymmetrical interdependence, this approach employs a mixed-methods design, combining quantitative analysis of tourism revenue, GDP, and GNI with qualitative examination of geopolitical events that may raise or lower the Travel Advisory rating. Rather than assuming the advisory acts as a tool of coercive foreign policy, this study tests whether advisory changes meaningfully shape Turkey’s economic performance or whether they simply reflect moments of instability inside the country. The findings support …

Imagery Intelligence And Presidential Crisis Decision-Making: The Case Of The Cuban Missile Crisis, Codie Mcdonald

Honors Theses

Although the Cuban Missile Crisis was a short period of time relative to our nation’s history, this research has illuminated how much information, tension, and impactful moments lie within each minute; and the fact is, intelligence collection absolutely is a main factor in the de-escalation of the nuclear threat. Without the intelligence collection and production that was completed and given to Kennedy, policy would not be able to be made nearly as easy. Throughout each moment of the crisis, generally speaking, IMINT was able to provide and support the most aid to President Kennedy and his advisers. While the degree …

Synthesis And Evaluation Of Amidoximes As Potential Pharmaceuticals Against Antimicrobial-Resistant Bacteria, Prudence Mange

Honors Theses

The rise of antimicrobial-resistant bacteria in the healthcare industry has led to devastating effects in recent years, ranging from increased risks associated with hospital treatment to longer illness duration, which may eventually lead to increased death rates (Naghavi, Mohsen et al, 2024). To combat this ongoing challenge, this project aims to synthesize amidoximes, which are organic derivatives of carboxylic acids with an oxime and an amino acid group. Amidoximes have been utilized in various clinical applications, including antituberculosis medication, hypotensives, antiarrhythmics, antibacterials, and antifungals (J. Chil et al., 2011). -- The focus of this project was to test their antibacterial …

Designing A Scalable Recruitment & Partnership System For The Leadership And Business Strategy (Lbs) Program Through Strategic Marketing And Brand Development, Daniela Padilla

Honors Theses

The Leadership and Business Strategy (LBS) program at Western Michigan University delivers a highly immersive experience that allows students to learn business by doing business. Students engage directly with executives, including CEOs, working alongside them on complex consulting projects with real companies. The program takes place at Sleeping Giant Capital, a Michigan-based private equity firm, where students operate in a real business environment and gain exposure to high-level strategy and decision-making. Yet despite its impact, many students only discover LBS after enrolling at the university. Student data reinforces this gap, showing that while most students know their intended major before …

The Moral Crisis Of Maternal Mortality In The Us, Jensen F. Ware

Honors Theses

This thesis argues that the US crisis of maternal mortality is not an unavoidable tragedy, but a moral and policy failure. I argue that maternal well‑being is one of the most important indicators of a society’s overall health. When mothers receive the care, respect, and support they need, it reflects the strength of healthcare systems, the culture, and our commitment to future generations. The continued loss of mothers from preventable deaths reveals a system that fails many women and their families, especially Black women, low‑income women, and those in rural communities. First, I introduce the issue of maternal mortality in …

It’S Still Happening: Conversion Therapy Laws Leaving College Students And More At Risk, Emma L. Mcconnell

Honors Theses

Conversion Therapy is still legal for adults across the United States, and for minors in many states. The laws and case law facilitating or preventing this discredited practice hang in the balance of whichever direction the Federal political climate moves at any given times. Even in states where Conversion Therapy is celebrated as "banned", populations of Americans that include the uniquely vulnerable students at religious universities are still subjected to it. This exploration and policy proposal solution prompts the total ban of Conversion Therapy and explains how a true legislative movement to that aim could begin.

High School Science Experience For Students With Cognitive Disabilities: A Pilot Study, Cassandra Wychers

Honors Theses

Although education has become more adaptive, inclusive of all students who learn differently including for people with cognitive disabilities, closer examination may reveal that high school science classrooms are still challenging learning spaces. Science is an important part of the school curriculum as it teaches students about engaging in the world around them while also encouraging skills involving evidence, inquiries, and critical thinking. All students are entitled to learn science in their classrooms even if they have a cognitive disability (Apanasionok, et al. 2019). Although there are many complexities to defining disability in the world and in education, this study …

An Exploratory Evaluation Of The Kalamazoo River Watershed Council: Assessing Organizational Impact And Value, Alexander Mendez

Honors Theses

The Kalamazoo River Watershed Council (KRWC) plays a central role in protecting, restoring, and promoting the long-term health of the Kalamazoo River watershed, a geographically expansive and ecologically complex system facing persistent challenges from legacy contamination, nonpoint source pollution, land-use pressures, and inequitable access to watershed resources. This honors thesis presents an exploratory organizational evaluation of the KRWC, assessing its role and relevance within the watershed, the effectiveness of its programs and partnerships, the strengths and limitations of its governance structure, and opportunities to strengthen its long-term sustainability and impact.

Guided by principles of Practical Participatory Evaluation (PP-E) and Fourth …

Running From The Headlines: Evaluating Levels Of News Consumption Attitudes Across Generations, Andrew Francis

Honors Theses

The primary goal of this research is to answer the question "What behavioral trends exist across various generations and other demographics when it comes to how people consume and interact with news coverage?" With newspapers and other traditional mediums for news consumption being largely phased out of our increasingly digital society, it is important for communicators and journalists to have a comprehensive understanding of how to best reach members of their desired audience. I have studied the data collected and analyzed what trends are apparent in the survey's sample size, which can hopefully be applied to the larger population. To …

The Effectiveness Of Telemedicine As A Pivotal Tool In Providing Accessible Medical Care, Peyton Wilt

Honors Theses

Telemedicine has emerged as one of the most transformative innovations in modern healthcare, offering new opportunities to bridge long-standing gaps in access, quality, and continuity of care. Rural and underserved communities in the United States face persistent barriers to healthcare, including provider shortages, geographic isolation, limited access to specialty services, transportation challenges, and socioeconomic disparities. These structural barriers often delay diagnosis, disrupt chronic disease management, and worsen overall health outcomes. Telemedicine provides a mechanism to address many of these obstacles by enabling remote consultations, real-time monitoring, follow-up appointments, and access to specialty providers through digital platforms.

This thesis examines the …

Changing Opinions: The Supreme Court After Dobbs, Lora E. Judge

Honors Theses

No abstract provided.

Early Warning Detection Of Gravitational Waves With Sgnl, Megan Norris

Honors Theses

Gravitational waves (GWs) provide a whole new spectrum with which to observe astrophysical events. Multi-messenger observations including GWs are of particular interest, and these are best facilitated by early warning searches of GWs, which are typically aimed at detecting binary neutron star (BNS) mergers. This work provides an introductory overview of gravitational waves and summarizes the origins and basic physical properties of neutron stars and black holes in binary systems, focusing on BNS mergers and the detection of gravitational waves with LIGO using a modeled search. We assess the performance of a new GW search pipeline called SGNL to evaluate …

Holistic Approaches To Lyme Disease Symptom Management, Leah Van Antwerp

Honors Theses

Lyme disease is a multisystem tick-borne infection that can lead to long-lasting symptoms even after standard antibiotic therapy, with Lyme arthritis being one of the most common and persistent complications. Due to limited research on this issue, rheumatoid arthritis (RA) will be discussed as a reference for understanding treatment options because it is a similar condition. Since many people continue to experience debilitating pain and reduced quality of life after treatment for Lyme disease, holistic approaches have become increasingly popular for symptom management. This literature review examines three holistic modalities-yoga, acupuncture, and diet modifications- and their effectiveness in alleviating arthritic …

Plant Vs. Animal Protein: Effect On Recovery, Performance, And Long-Term Health, Claudia Stachura

Honors Theses

Protein plays a fundamental role in muscle repair, growth, and athletic performance, which has led to increased interest in how different protein sources compare, particularly as plant-based diets become more common among athletes and physically active individuals. The debate surrounding plant-based versus animal-based protein sources primarily focuses on differences in protein quality, amino acid composition, digestibility, and potential long-term health implications. This paper examines current evidence comparing the effectiveness of plant and animal protein sources in supporting muscle protein synthesis (MPS), resistance training adaptations, recovery, and performance, while also considering broader health and environmental outcomes.

Protein supports muscle growth by …

The Role Of Sustainability In Family And Consumer Science Curricula, Emily Hill

Honors Theses

As climate change intensifies and global food systems face growing environmental pressures, there is an increasing need to prepare younger generations to respond to these challenges. Sustainability education is increasingly recognized as essential for helping students understand the connection between human actions, environmental resilience, and their overall well-being. This form of education already has a foundation in the Family and Consumer Sciences (FCS) curriculum. This study examines the effects of integrating sustainability lessons into secondary Family and Consumer Sciences food and nutrition courses in a rural Michigan high school. It was hypothesized that if students participate in sustainability presentations and …

Sumak Kawsay: Un Argumento Para El Empoderamiento De Los Pueblos Indígenas Y Sus Cosmovisiones, Charlie Degraves

Honors Theses

El sumak kawsay, un conjunto de conocimientos y prácticas propios de los pueblos indígenas andinos y amazónicos, es una buena alternativa a un futuro capitalista y globalizado. La devolución de los terrenos y las soberanías de toda nación originaria, y por ende la realización del sumak kawsay y las demás cosmovisiones indígenas, es clave para evitar la destrucción de la vida en nuestro planeta. El sumak kawsay, según los pueblos originarios andinos y amazónicos, consiste en 10 temas. En orden de importancia tenemos: 1) soberanía comunitaria, 2) equilibrio y convivencia, 3) colectivo e interrelacional, 4) ancestral, 5) minimalista, 6) una …