Digital Commons Network^™

El Mar Y La Gente: Hacia Una Contextualización De Lo Indígena En El Botón De Nácar, Jonathan Braden Taylor

Honors Theses

El presente trabajo analiza las ramificaciones ontológicas, epistemológicas, y políticas del botón de nácar, un documental hecho en 2015 por el cineasta Patricio Guzmán. El siguiente análisis busca poner esta obra cinemática en el contexto de la formulación y el desarrollo del estado-nación chileno, lo cual ha ocurrido a expensas de las personas indígenas de la zona. Se observa que se emplea significación verdaderamente descolonizada en representaciones y discusiones de espacios acuáticos, lo cual engendra avances teóricos que utilizo para contextualizar el filme. Se sostiene que los efectos políticos de dicha significación descolonizada se ponen en marcha productivamente cuando son …

Identity-Making And Spatialization Among Colby College's International Students, John G.G. Shamgochian

Honors Theses

This thesis presents the research that I have done for the award of Honors in Anthropology. The following text begins with a vignette that highlights identity-making and spatialization among international students in a moment of precarity and visibility. The “Introduction” records the development of my research from its initial topics to its current form, my methodology, my positionality, and the ethics of my research. Following this, in the chapter titled “Internationality,” I lay out the interwoven social, institutional, and political processes which shape the experiences of academic migrants. Because the purpose of this chapter is to fully contextualize my argument, …

The Tetralemma Of Nothingness, Samuel O. Sessions

Honors Theses

Grammatically, the question is rather simple. It is when we set out to answer the question that it suddenly becomes complex. What is nothing? Its very asking seems almost impossible because the ‘is’ within it brushes up against its meaning, producing paradox. How do we even begin to get at a something that is not a something? Immediately, you remark how similar this task is to a child chasing fairies in the forest or hunting for ghosts in the attic. Will we be doomed from the outset? If so, then what is the point? Our many predecessors have had varying …

The Predictive Power Of The Term Structure Under Unconventional Monetary Policies, Luying Yang

Honors Theses

Previous research has confirmed a positive relationship between the slope of the yield spread and future economic growth. Since the start of the Great Recession, a number of developed economies have hit the zero lower bound and adopted unconventional monetary policies such as large-scale bond/asset purchase programs and negative interest rate policies. This paper finds that the yield spread’s predictive power generally deteriorates after the central bank adopts its first bond purchase program. However, there is no general pattern of how these unconventional monetary policies impact the yield spread’s forecasting ability across countries.

Analyzing The Role Of Noncoding Rna-Derived Rnas In Human Cancer, Yulong Huang

Honors Theses

To date, there are no known cures or effective preventative measures for cancer. Research has been conducted on small noncoding RNAs (ncRNAs) and noncoding RNAderived RNAs (ndRNAs) as potential contributors to cancer suppression and/or proliferation. Tumorigenesis may be slowed by identifying and targeting some ndRNAs that are frequently presented in different cases of cancer, which may improve patient prognoses. To identify these ndRNAs, we utilized next-generation sequencing (NGS), a DNA/RNA sequencing technology, to sequence nucleotides in the human transcriptome. Then, we analyzed NGS data in accordance with information from The Cancer Genome Atlas (TCGA) and Sequence Read Archive (SRA) to …

Understanding The Behavior Of Ionic Liquids In Poly (Methyl Methacrylate) Through Molecular Dynamics, Alejandro Gallegos Tovar

Honors Theses

Ionogels are polymer networks swollen by ionic liquids (ILs). They are used for electrochemical devices (lithium-ion batteries, thin-film transistors, and fuel cells) and as permeation membranes for gas separation. The interactions and phase behaviors of an ionic liquid (IL) in a polymer are the most important factor when building ionogels. The molecular behavior between poly(methyl methacrylate) (PMMA) and 1-butyl-3- methylimidazolium with four different anionic structures has been studied. The behavior between ILs and polymers is governed by a complex mix of factors such as polymer concentration, polymer and IL hydrophobicity, inter and intramolecular forces, and temperature. Molecular simulations of different …

Covid-19 Media Exposure And Parenting, Abagail Roy

Honors Theses

Rationale- The COVID-19 pandemic has led to a drastic change in the way of living for most parents. A study conducted during the lockdown of Italy found that parents experienced a high level of distress (Marchetti et al., 2020). Several studies have been conducted to find how media exposure and screen time affect children but much less research has been conducted on how media exposure is related to parental feelings and parenting.

Methods- The aim of this paper is to explore the role of COVID-19 media exposure in parental aggravation, closeness to children, parental self-regulation, intolerance of uncertainty, and resourcefulness. …

Integrative Genome Assembly Of Staphylococcus Epidermidis And Staphylococcus Hominis Strains, Cana L. Brown

Honors Theses

Due to rapid advances in sequencing technology, it is becoming increasingly easier to assemble unknown genomes from millions of short sequencing reads of nucleotides taken from the full genomic sequence (Hernandez, 2008). In this study, we used various computational programs to align reads from unsequenced strains of the bacteria Staphylococcus epidermidis and Staphylococcus hominis into a hitherto undefined, single contiguous genomic sequence. We used SPAdes to assist with template free assembly (Bankevich, 2012), BLAST to identify a suitable reference genome from closely related species (Madden, 2013), Bowtie2 to align our reads to the reference genome, SAMtools to sort and organize …

Thermal And Thermophysical Properties Of Anionic Amines And Their Aqueous Solutions For Co2 Capture In Confined Environments, Randi Swanson

Honors Theses

Air revitalization for the International Space Station (ISS) has been identified by NASA as a mission critical need which requires improvement. The current method uses13X zeolite, a solid adsorbent, to adsorb carbon dioxide. While this is effective, the zeolite adsorbent produces dust that is unwelcome on the space station. Furthermore, the adsorbentis too sensitive to humidity in moderate temperature gas streams [1]. Aqueous solutions of ionic amines show promise as a safe and efficient solution, as they do not volatilize and are not water sensitive [2]. Specifically, anionic amines have the most potential because of the amine functional group’s ability …

Improving Psychological Pre-Surgical Evaluations For Chronic Back Pain By Linking Data Of Pre-Surgicalmmpi-2-Rf And Post Surgical Pain Interference On Emotional And Physical Functioning, Ethan Hayes

Honors Theses

Chronic pain is running rampant, and its treatment options can sometimes be more dangerous than the pain itself. With such a widespread prevalence – and chronic in the name - numerous individuals are left to deal with daily anguish that fails to abate. This Honors Thesis examines a sample of patients presenting with chronic pain and attempts to validate previous research investigating what factors determine candidacy for a possible treatment, dorsal column spinal stimulator surgery. Research supports that this treatment may have beneficial effects, but patients are sometimes unable to gain respite, despite having a stimulator implanted into their lower …

A Hybrid Decision Tree - Neural Network (Dt-Nn) Model For Predictive Maintenance Applications In Aircraft, Jarrod Carson

Honors Theses

As the Age of Information has evolved over the last several decades, the demand for technology which stores, analyzes, and utilizes data has increased substantially. For countless industries such as the medical, retail, and aircraft industries, such technology is crucial to their operation. This project proposes a hybrid machine learning model consisting of Decision Trees and Neural Networks which is able to classify data of varying volume and variety effectively and efficiently. The model’s structure consists of a decision tree with each node of the tree containing a neural network trained to classify a specific category of the output using …

Factors Contributing To Diminished Long-Term Outcomes Of Secondary Infections, Alia Tayara

Honors Theses

It is widely known that patients suffer diminished long-term outcomes in the years following secondary infections, infectious diseases that occur during or after treatment of a primary infection such as influenza or COVID-19. One common secondary infection is pneumonia, which has become the most fatal hospital-acquired infection. The bacterium responsible for pneumonia is known as Pseudomonas aeruginosa. The cytotoxic supernatant in these studies was generated from a PA103 strain of Psuedomonas aeruginosa with a type III secretion system that maintains the ability to transfer exoenzymes ExoU and ExoT into target cells during infection. The focus of the following studies was …

Relationship Between Narcissism, The Economy, And The Pandemic, Ruby A. Staten

Honors Theses

Narcissists are more likely to be found in individualistic cultures. The study focuses on the economic decline associated from the pandemic and the reduced narcissism levels in the population. Narcissism levels from the University of South Alabama undergraduate students would be lower in Fall 2020 compared to Fall 2019. This was assessed using students enrolled in introductory psychology courses during either Fall 2019 or Fall 2020 semesters who completed the Narcissistic Personality Inventory during a subject pool registration process. Predictions were made that the NPI scores would be lower for the Fall 2020 sample compared to the Fall 2019 sample.

Assessment Of Hypothermia As A Correlate Of Pde4 Inhibitor-Induced Nausea In Mice, Marianna Susan Oditt

Honors Theses

Type-4-cAMP-phosphodiesterases (PDE4s) are a group of isoenzymes that hydrolyze the second messenger cyclic adenosine monophosphate (cAMP). PDE4 inhibitors have many therapeutic uses including reducing inflammation, however, they also have side effects like nausea and emesis, which have diminished the clinical utility of PDE4 inhibitors. When administered to mice, PDE4 inhibitors have been shown to cause hypothermia. Given that nausea and emesis in humans are also associated hypothermia, this project served to determine whether PDE4 inhibitor-induced hypothermia may represent a correlate of nausea and/or emesis in mice. To this end, the current literature was screened for articles that explore nausea, emesis …

Functionalization Of Novel Pp5 Inhibitors, Hope P. Hill

Honors Theses

The overexpression of protein phosphatase 5 has been correlated to tumor cell reproduction making it a candidate for small molecule drug therapy. Selective and potent inhibition of protein phosphatase 2A (PP2A) enzyme has been previously achieved through the development of the molecule fostriecin with key functionality being a lactone and unsaturated linear chain. The large synthetic overhead of fostriecin has led to exploration of other small molecule inhibitors that could mirror fostriecin’s interaction with the active site in the catalytic domain of PP5. The naturally occurring inhibitor, cantharidin, is functionalized with an epoxy containing eleven carbon chain to optimize binding …

Gq-Mediated Ca** Signals In Human Airway Smooth Muscle Cells, Hanna Viktoria Bobinger

Honors Theses

Current asthma therapies include corticosteroids, long acting β2-adrenergic receptor (β2-AR) agonists paired with corticosteroids, or short-acting β2-AR agonists used in rescue inhalers. Chronic use of β-agonists results in diminished effectiveness, and use of long-acting β-agonists can even exacerbate asthma symptoms; this is partly because anti-inflammatory therapy does not directly address the exaggerated airway narrowing due to excessive shortening of airway smooth muscle (ASM), which is the hallmark of asthma. These observations led our collaborators to investigate other potential asthma therapies – bitter taste agonists. 2 Bitter taste agonists, such as chloroquine, activate a subset of Gq-coupled receptors known as bitter …

A Foray Into The Interval Timing Capabilities Of Tufted Capuchin Monkeys (Cebus [Sapajus] Apella), Gryff Griffin

Honors Theses

Time is a critical part of life and timing on the range from milliseconds to minutes has proven to be critical for several behaviors such as foraging and movement. While the exact neurological structures of interval timing are currently undefined, several studies have been completed comparing the interval timing capabilities of humans and nonhuman primates. However, these studies have unanimously utilized members of Macaca, which limits the abilities for researchers to make apt comparisons between humans and all nonhuman primates. This study sought to investigate whether tufted capuchins (Cebus [Sapajus] apella) have the capability to measure time …

Heavy Metals Found In Juul's Electronic Cigarettes, Joshua F. Gesselberty

Honors Theses

Electronic cigarettes better known as e-cigarettes have been consistently rising in popularity with new products entering the market daily. E-cigarettes function by vaporizing a liquid composed of propylene glycol, glycerin, benzoic acid, nicotine, and flavor additives with the use of a metallic heating element. This vapor produced is then inhaled by the user. The composition of this liquid is critical to discovering the possible health effects.

This study investigates the presence and concentrations of heavy metals in the e-liquid before and after vaping. An ICP-MS was used because of its ability to scan several metals rapidly and its high sensitivity. …

The Functionally Relevant Role Of Sdrna-19b And Sdrna-24 In Prostate Cancer, Addison A. Barchie

Honors Theses

In recent studies small nucleolar RNAs (snoRNA) have been shown to be processed into smaller microRNA-like fragments known as sno-derived RNA (sdRNA). We recently identified 9 snoRNAs that contribute to prostate malignancy using The Cancer Genome Atlas (TCGA) patient prostate tumor next-generation sequencing datasets. These snoRNA were found to be processed into sdRNAs, heavily misexpressed in prostate cancer cell types 8140 and 8550, and shown to function by binding Ago proteins in order to impact mRNA translation. SdRNA-19b and sdRNA-24 in particular stood out as having significant differential expression in prostate cancer vs. control tissue. Interestingly, the targets for sdRNA-19b …

The Role Of Inflammasome In Vascular Remodeling Following Injury, Ted Amadi

Honors Theses

The purpose of the project presented in this thesis is to assess the contribution of inflammasome activation in mediating vascular wall remodeling that occurs following carotid artery injury due to decreased blood flow. To examine this, we used a mouse model of carotid artery ligation in mice lacking the expression of a key mediator of the inflammasome signaling pathway. Following ligation, we completed a histological assessment to compare the degree of the neointima formation and expression of inflammasome related proteins in both injured and the non-injured contralateral carotid artery in both wild-type (WT) and Caspase 1 knockout mice (Cas1 -/-).

Determination Of Pollutant Load Reductions To Three Mile Creek As A Result Of The Implementation Of Storm Water Bio-Infiltration Basins On The Usa Campus, Jordan E. Blackmon

Honors Theses

Three Mile Creek has been identified as an impaired urban stream and is now a priority for cleanup for both the City of Mobile and the Alabama Department of Environmental Management. Methods to better manage storm water runoff on the USA campus have begun, with a goal to reduce sediment and nutrient inputs to Three Mile Creek. Both sediment and nutrient inputs to Three Mile Creek disrupt habitat and lower dissolved oxygen concentrations, which are detrimental to overall stream health. Low Impact Development strategies are an innovative way to use nature-like, green-infrastructures to minimize storm water runoff quantity and improve …

Amplification And Filtering Stage For An In-Home Wireless Polysomnograph, Seth Young

Honors Theses

Obstructive sleep apnea is a sleep disorder that tends to be easily treatable but, for most sufferers, is undiagnosed. To lower the economic barriers to screening the design of a portion of a polysomnograph, or obstructive sleep apnea testing tool, is considered. A filtering and amplification stage is theorized, simulated, and constructed for testing. The stage, consisting of three cascaded 1st order Butterworth low pass filters and amplifiers, did not achieve the target signal to noise ratio for a sinusoidal waveform of amplitude 200µv, but showed promising signal to noise ratios for waveforms with amplitudes as low as 600µv. The …

Comparative Analysis Of Computationally Accelerated Ngs Alignment, Ada Chaeli Van Der Zijp-Tan

Honors Theses

The Smith-Waterman algorithm is the basis of most current sequence alignment technology, which can be used to identify similarities between sequences for cancer detection and treatment because it provides researchers with potential targets for early diagnosis and personalized treatment. The growing number of DNA and RNA sequences available to analyze necessitates faster alignment processes than are possible with current iterations of the Smith-Waterman (S-W) algorithm. This project aimed to identify the most effective and efficient methods for accelerating the S-W algorithm by investigating recent advances in sequence alignment. Out of a total of 22 articles considered in this project, 17 …

Caregiver Knowledge, Perceived Self-Efficacy, And Level Of Confidence In Limiting Bedtime Screen Use In Preschoolers, Emily Hollingsworth

Honors Theses

Screen time usage is a major factor leading to negative behavioral and health consequences in young children. Screen time also affects sleep, with prior research showing a significant association between screen time, particularly at bedtime, and reduced sleep duration and increased sleep problems. The initial aim of this research was to measure and attempt to increase, through an educational intervention, the knowledge, perceived self-efficacy, and confidence of study participants/primary caregivers with regard to limiting the bedtime screen use of their preschoolers with the goal of health promotion. It was intended to be a quantitative, quasi-experimental, multi-site, pre- post-intervention case study. …

Health Care Providers' Attitudes Toward Screening Patients For Sexual Violence And Intimate Partner Violence, Judith Hoyt

Honors Theses

The primary purpose of this quasi-experimental study of health care providers at a faith­based clinic for uninsured adults in a metropolitan area was to detennine health care providers' knowledge of and attitudes towards the use of SV and IPV screening tools. This study measured a volunteer group of primary care providers' knowledge and attitudes towards SV and IPV screening tools before and after applying an educational intervention presenting the benefits of screening and identifying patients who have previously been, currently are, or at risk to suffer abuse. A total of IO eligible participants completed all elements of the study. The …

Women Outside The Household In Early Modern Germany, Abigayle Edler

Honors Theses

During the early modern period, women were highly regulated by society. This regulation included everything from sumptuary laws restricting consumerism and clothing to exclusion from guilds and other occupational restrictions. Women were generally expected to remain within the household sphere and were discouraged from deviating from traditional norms. However, some early modern German women were able to challenge and subvert these expectations. Given the prescribed gender roles often enforced within early modern German society, what prominent roles and industries, if any, were women able to participate in outside of the household? “Women Outside the Household in Early Modern Germany” utilizes …

Iot-Enabled Environmental Monitoring Technologies, Clayton Suell

Honors Theses

Environmental monitoring is essential to protect human life and the environment due to issues such as global warming, pollution, and weather phenomena like hurricanes. To this end this thesis presents a prototype IoT (Internet of Things)-enabled environmental monitoring network. The network will include the ability to collect data from various locations that will be uploaded to a cloud so that the data can be accessed from any device with a network connection allowing for greater environmental awareness and a database that can be used for environmental analysis. The network will be flexible enough that every data collection point will either …

Developing A Deterministic Polymorphic Circuit Generator Using Random Boolean Logic Expansion, Trinity Stroud

Honors Theses

Securing applications on untrusted platforms can involve protection against legitimate endusers who act in the role of malicious reverse engineers and hackers. Such adversaries have access to the full execution environment of programs, whether the program comes in the form of software or hardware. In this thesis, we consider the nature of obfuscating algorithms that perform iterative, stepwise transformation of programs into more complex forms that are intended to increase the complexity (time, resources) for malicious reverse engineers.

We consider simple Boolean logic programs as the domain of interest and examine a specific transformation technique known as Iterative Selection and …

Utilizing Acoustic Levitation To Determine Ionic Liquid Effects On Enthalpy Of Polymerization, Davina V. Ho

Honors Theses

Ionic liquids (ILs) are emerging as an eco-friendlier alternative to traditional organic compounds. The hope with ILs in this project is to incorporate them with resins used in 3D printing to act as plasticizers which will in turn help prolong the life of the printed object. A common issue with plasticizers like phthalate in particular is they can leach out of plastics due to their vapor pressure which leads to decreased performance and can also pose a health risk being released into its surroundings or atmosphere. A major benefit of incorporating ILs in with resins comes from their low volatility …

Comparison Of Resilience, Empathy, Anxiety, And Depression Levels In College Aged Individuals Who Have A Sibling With A Developmental Disorder And Those Who Have A Typically Developing Sibling, Cecelia Prentiss

Honors Theses

Observing and analyzing the relationships between siblings can bring insight to what kinds of behaviors they will be inclined to have, as well has how prominent those behaviors will be. Specifically, it is important to analyze and compare levels of resilience, empathy, anxiety, and depression in individuals who have a sibling with a developmental disorder (DD) and those who have a typically developing (TD) sibling. This research looks to find out more information on college-aged individuals who have a sibling with a developmental disorder. There have been many studies that have conducted research to show how children and older adults …