Digital Commons Network^™

Effects Of Cytochalasin D On Motor Function In Drosophila, Airyel Noguera

Honors Theses

Actin proteins play an important role in microfilaments, one of the three components of the cytoskeleton of the cell. The actin protein is responsible for cellular functions such as with their role in neuromuscular junctions. The dynamics of these proteins can be further explored with manipulation of polymerization through the treatment of a biochemical drug, Cytochalasin D. This fungal toxin caps the ends of actin filaments, destabilizing them by inhibiting G- and F-actin monomers from binding. Treating Drosophila in their early embryonic stage with this drug after permeabilization can give insights on the importance of actin proteins at neuromuscular junctions …

Pilot/ Validation Of Protocol For An Alternative To Clinical, Morgan Sylvester

Honors Theses

All across the country, Clinical Microbiology laboratories are being consolidated into one location for an entire hospital network10. Though this helps reduce cost and staffing needs, it creates issues for the next generation of Medical Laboratory Scientists (MLS) trying to find clinical sites to complete clinical practicum rotations to complete the necessary certification processes. To combat this issue, it was proposed that MLS programs create alternative curriculums to offer in place of clinical rotations to reduce the amount of time students need in these rotations from three weeks to one week. This study investigated one alternative with the intent that …

Exploring The Relationship Between Diet And Mental Health, Emory Layne

Honors Theses

Dietary patterns in Western societies have shifted over the past century due to the rise of food manufacturing and technological advancements. Ultra-processed foods now account for approximately half of the daily energy intake in high-income countries. Similarly, the national mental health crisis emerged in the 21st century and worsened after the COVID-19 pandemic. The changes in diet have impacted the gut microbiome, which interacts with the brain through the bidirectional gut-brain axis. Research suggests the concept of the gut-brain axis is a principal indicator of diet’s impact on mental health. However, this area of research is still emerging and requires …

Knowledge Gaps And Personal Experiences: A Qualitative Examination Of Women's Menstrual Health And Birth Control Choices, Danielle M. Jackson

Honors Theses

Women all over the world face significant knowledge gaps and societal perceptions (Mukanga et al., 2023) regarding menstruation and birth control, which impact their understanding of both the physical and mental symptoms associated with these experiences. From a young age, women are often left to navigate these processes without sufficient education or support, leading to confusion, misconceptions, and a lack of empowerment when it comes to managing their reproductive health (Guendelman et al., 2000). The stigma surrounding topics like menstruation and hormonal contraception can further isolate women, making it difficult for them to seek reliable information or openly discuss their …

Family Involvement In Pediatric Occupational Therapy Interventions: A Qualitative Study, Maylee S. Collins

Honors Theses

In recent years, family involvement has increasingly been recognized as a critical component of effective pediatric occupational therapy (OT) interventions. Research suggests that parents who actively participate in OT can enhance a child’s engagement, motivation, and therapy outcomes (Sayers et al., 2021). However, the specific experiences and perspectives of parents and families, particularly regarding how they view their role and the impact of their involvement on therapy outcomes, remain underexplored. This study aims to investigate parental perceptions, challenges, and the perceived benefits of involvement in OT interventions, and adding to the understanding of how family collaboration can optimize therapeutic outcomes …

Body Composition And Self-Image: Exploring The Impact On Exercise Motivation And Behavior, Demitria J. Watson

Honors Theses

This study examines how self-perception and body composition (body fat percentage, lean mass, etc.) influence psychological and behavioral outcomes among college students. The research explores how body composition metrics are related to psychological factors such as stress management, enjoyment of physical activity, and leisure activity, and how appearance scores, as a reflection of self-perception, influence these outcomes. Drawing on a sample of 100 undergraduates from Eastern Kentucky University, data were collected through self-reported surveys measuring body satisfaction, exercise frequency, and motivational factors, alongside objective body composition metrics. Statistical analyses revealed that higher appearance scores were associated with better stress management …

Innoxtract Vs Prepfiler Bta: Extracting Dna From Burned Skeletal Remains, Kaitlin Brown

Honors Theses

The purpose of this study was to investigate the different levels of DNA extraction in thermally altered samples by comparing the InnoXtract and PrepFiler BTA extraction kits. PrepFiler BTA is a DNA extraction kit designed to use for bone samples which uses silica coated magnetic beads to extract DNA from powdered bone. InnoXtract is a specialized kit for bone samples which uses the same silica coated magnetic bead method for DNA extraction. Burned skeletal remains pose a challenge since high temperature exposure denatures the DNA and degrades DNA that can be extracted. For this experiment, porcine femurs were used as …

Determining The Effect Of Physical Activity Level On The Amount Of Trace Dna Deposited On A Non-Porous Surface, Sarah Marsh

Honors Theses

In the field of Forensic Science, trace DNA has been used to help identify potential offenders for a number of years. Researchers have conducted studies into how trace DNA behaves on certain surfaces such as fabric and wood. They have found that surfaces seem to have a significant influence on how much DNA is deposited and persists on the surface. However, no work has been conducted into how physical activity effects DNA deposition. The goal of this research was to evaluate the relationship between physical activity and DNA deposition. Seven individuals agreed to participate in this project by providing biological …

The Relationship Between Women's Use Of Birth Control Pills And Their Perceptions Of The Mental Health Effects (Depression And Anxiety) Of The Pill, Andrea Bonano Mendez

Honors Theses

The National Library of Medicine published an article mentioning how hormonal contraception might cause and sustain depression in some patients (Mu & Kulkarni, 2022). Currently, approximately 25% of women ages 15-44 who are currently using a form of contraception rely on the pill as the primary method (Cooper, 2024). However, there is still no definite yes or no answer in terms of whether the use of birth control pills can lead to mental health effects. The objective of this paper is to see what the current perceptions on whether birth control pills have an effect on mental health based on …

Profiling Gene Expression In Epstein-Barr Virus Infected Heart Tissue, Jacob Smith

Honors Theses

The overall purpose of this project is to evaluate active gene expression in heart tissue samples infected by the Epstein-Barr virus. By cataloging active gene expression, one could elucidate the cellular and molecular mechanisms that underpin viral infection’s role in the development of heart pathology. This was accomplished by extracting nucleic acids from homogenized heart tissue samples, employing reverse-transcription PCR (RT-PCR) to synthesize cDNA from extracted mRNA), and performing a qPCR to quantify the levels of gene expression from these cDNA samples. The genes explored within this project were: Hsp60, a chaperonin protein involved in mitochondrial stress response; BCL2, an …

Redefining Beauty And Boundaries: The Evolution Of Mac Viva Glam’S Pr Campaign As A Case Study In Shaping Dei Discourse Amid A Changing Political Landscape, Abigail Kennedy

Honors Theses

The relationship between diversity, equality, and inclusion (DEI) in the beauty industry and the emergence of anti-DEI laws nationwide is examined in this thesis. Using MAC Cosmetics' Viva Glam campaign as a case study, this research highlights how public relations tactics in the beauty industry have traditionally supported inclusive values, embracing representation across lines of color, gender, sexual orientation, and health. On the other hand, new legislative initiatives in states like Florida, Texas, and Kentucky demonstrate a burgeoning political movement that seeks to eliminate DEI initiatives in public institutions and education. This thesis examines the ramifications of such through a …

Observations From The Void: A Lament For Earth, Seth Petersen

Honors Theses

The Earth is a world full of art and many different forms of expression. Puppetry is a medium that has been used for hundreds, or even thousands, of years as a way to breathe life into objects. Through the use of both shadow and hand puppets a performance was created to follow the script of a written poetry collection. This collection of poetry was written from the perspective of an alien observer as they watch Earth from light-years away to determine if they are a threat to the universe. To figure this out they look at various aspects of humanity …

Health Amongst Pilots, Becoming Aware And Solving The Problems: A Quantitative And Qualitative Narrative Analysis Of Pilots, Kelsi Howard

Honors Theses

Pilots of all calibers from commercial to cargo are one of the world's leading factors to economic growth, political dominance, and personal satisfaction amongst individuals, so why is there not more health opportunities for this group of workers? There is hardly any mention of a pilot's physical health, most of the articles when posted are based around a pilots mental health, with little to no concern for their physical health. This could primarily be due to the fact that airline pilots have a fear of being at risk of losing their medical license. Meanwhile others are in search of information …

Connect 2 Cope: Stress And Coping Strategies Associated With University Honors Students, Anna R. Rodgers

Honors Theses

Coping and connecting are two things that college students don’t take a course in but are essential qualities they will need beyond their time in the university, in both work and life. This research sought to understand how students at Southern Illinois University, with special focus on Honors students, experience stress and view connection as a coping mechanism. It gives insights into sources of stress, including pressures that are external to university life and impact student mental health. The participants included SIUC Honors Students and SIU Non-Honors Students. I was also able to ask each group of students their perceptions …

Walking In Town: A Study Of Walkability And Its Impacts On Students At Eku, Emma Garland

Honors Theses

This project explores the current state of walkability in Richmond, Kentucky, with a specific focus on connectivity between Eastern Kentucky University (EKU) and essential services in the surrounding community. Utilizing the PRECEDE-PROCEED model as a planning framework, the study combines secondary demographic health data as well as

primary data collection—including student surveys and a walkability audit using a modified Delaware Walkability Assessment Tool—to assess pedestrian infrastructure, access to amenities, and safety concerns. Findings reveal a lack of continuous, safe, and accessible walking routes, limiting physical activity and contributing to broader health disparities. Based on these findings, two primary evidence-based interventions …

Diel Patterns Of Biogeochemical Indicators In Tidally-Dominated Creeks, Juliana Calderone

Honors Theses

Marshes and swashes are vital environments as a controlling barrier between land affected by various pollutants and the ocean. Eutrophication and the effects of this process can be detrimental for the areas experiencing it. I am interested in ways areas that have little contact with human interactions compare to areas that are heavily urbanized, and whether either of these locations is at a higher risk for eutrophication. Using spectrophotometry and fluorometry, I analyzed samples collected from the relatively undeveloped and restricted-access locations of Waities Island Beach and Dunn Sound monthly for dissolved nutrients, and chlorophyll. At the time of sampling, …

Tetradrachms, Shekels, And Denarii: Cross-Cultural Exchange In Money At The Edges Of Greece And Rome, Miles Thompson

Honors Theses

This thesis focuses on the coin collection of the University of Mississippi Museum. I cataloged ancient coins in its collection through consulting online databases and reference books, and designed an exhibition to display some of the notable examples. This exhibition was based around the theme of cross-cultural interaction between Greek and Roman cultures and other ones towards the edges. It had both a physical and virtual component, and was displayed in Bryant Hall, and the museum’s website. I provide greater historical depth and research on some of the coins I cataloged that illustrate these cross-cultural interactions well. This exhibition successfully …

Healthcare Experiences And Pain Dismissal By Healthcare Professionals, Amanda Warren

Honors Theses

Background. Pain dismissal by healthcare professionals has gained recent attention in popular culture as people have come forward to discuss their own experiences with this issue. Pain dismissal is prevalent within the healthcare system, and college-aged young adults may be particularly vulnerable to experiencing pain dismissal because of their age. College students may also be influenced by societal factors that may affect their attitudes towards seeking help and advocating for themselves during healthcare visits. There is limited research on college students' attitudes and behaviors on seeking help after experiencing pain dismissal by a healthcare provider. This study aims to 1) …

The Impact Of The Mediterranean Diet On Depression: A Narrative Review, Emma Kate Schaaf

Honors Theses

Background. The Western diet has extensive negative ramifications on physical health and emotional well-being. The Mediterranean diet, widely regarded as one of the healthiest eating patterns in the world, may have the ability to improve psychological conditions. This study aims to examine existing research from randomized control trials (RCTs) on the association between depression prevalence and the Mediterranean diet.

Methods. The following review was conducted using PRISMA guidelines and the Google Scholar and PsycInfo databases. The criteria for inclusion were that studies: 1) were randomized control trials (RCTs) examining the Mediterranean diet; 2) included samples of adults (i.e., > 18 years …

Creative Expression Through Worldbuilding: A Study On The Connections Between Literature And Music Through Analysis Of Brandon Sanderson's The Stormlight Archive, Lauralei S. Palmer

Honors Theses

This thesis examines the worldbuilding connections visible throughout fantasy literature and musical works. Though their tools seem different, authors, composers, and performers use equivalent techniques to draw in their audiences and produce an immersive, emotional experience. This research focuses on American author Brandon Sanderson’s highly detailed worldbuilding in his epic fantasy series, The Stormlight Archive. The Stormlight Archive exhibits the three pillars of worldbuilding: completeness, invention, and consistency. This research also examines Franz Liszt’s Les Préludes, a symphonic poem based on Alfonse Lamartine’s poem, Ode. Finally, this thesis culminates in the fusion of literary and musical worldbuilding in description …

You Are Wasting Your Time Here, You Are The One Who Has To Disappear: Extractivism And Violence Against Environmental Defenders In The Amazon Basin: A Case Study Of Peru And Colombia, Alaina K. Addy

Honors Theses

This thesis explores the systemic relationship between extractivism and violence against environmental defenders in the Amazon Basin, focusing on case studies from Peru and Colombia. Through a comparative, qualitative analysis of the experiences of Jani Silva in Putumayo, Colombia, and the Pacheco family in Madre de Dios, Peru, it argues that violence against defenders is not incidental but a structural outcome of extractive systems. Whether tied to legal or illegal activities, extractivism damages the environment, causing a need for protestors and defenders of the land. However, the activities continue, operating through corruption, impunity, and state neglect. This study, drawing on …

A Chemical Investigation: Monitoring Cannabidiol Concentration In The Presence Of Ionic Liquids, Hannah E. Mabie

Honors Theses

Cannabidiol (CBD) is a non-psychoactive cannabinoid from the plant, Cannabis sativa. CBD’s structure degrades over time and other minor cannabinoids are formed when in contact with organic solvents. This is a growing area of interest due to the Agriculture Improvement Act (The Farm Bill) in 2018, which led to growing marijuana consumption and increased CBD markets. Monitoring the concentration of CBD can be used by forensic investigators and researchers to determine how CBD interacts with solvents, like ionic liquids. In this study, different ionic liquids were used to determine the best route of solubility and if choline based ionic liquids …

Exploration Into Homotopy Equivalence And Vietoris-Rips Complexes, Alexander J. Mobley

Honors Theses

An important question in discrete topology and geometry is how to recover the structure and characteristics of a manifold when only given a finite set of points sampled from that manifold. Thus, if mathematicians have a point cloud of data which induces a discrete metric space, they look for some structure to these points. Understanding the structure of these points often gives needed insight to solve this problem. One such way to determine structure to these points is to use these points to construct a Vietoris-Rips complex. In abstract, Latschev shows that this allows us to recover the homotopy type …

Exploring Contemporary Issues Through Accounting Case Studies, Emaline Myers

Honors Theses

This thesis was completed as part of the course “Accounting 420- Independent Study” under the guidance of Dr. Victoria Dickinson and includes a collection of five case studies exploring the role of accounting, ethics, and policy in today’s world. Each case investigates how financial information, government decisions, and business strategy intersect, and what that means for professionals entering the accounting field. The topics covered in this thesis range from international financial fraud to environmental disclosures, military spending, public education, and small business development. Several key takeaways emerged from the completion of these cases. Case Study I highlights issues in global …

The Defect Within You, Sarah Spencer

Honors Theses

This thesis is a collection of science fiction short stories exploring human limitations in our era of unprecedented influence over the world. Despite everything we can accomplish, we are not as powerful as we think we are. My stories focus on how this manifests in our embodiment and our relationships with our bodies.

Investigating The Cytotoxic Effects Of Amino Acid-Based Ionic Liquids And Peg-Pla Nanoparticles On Mcf10a Human Breast Epithelial Cells For Drug Delivery Applications, Ella C. Mertins

Honors Theses

This study investigates the cytotoxic effects of polyethylene glycol-polylactic acid (PEG-PLA) nanoparticles (NPs) both bare and coated with choline-based ionic liquids (ILs) on MCF10A human breast epithelial cells. The goal was to evaluate how IL-modified NPs influence cell viability at varying concentrations and to assess their potential as drug delivery systems. Three choline-based ILs, Choline-L-Asparagine 1:1, Choline-DL-Isoleucinate 1:1, and Choline-L-Leucinate 1:1, were used as surface coatings for PEG-PLA NPs. Additionally, the ILs were tested independently to establish a baseline for their cytotoxicity. Using a luminescent ATP-based viability assay following the treatment of MCF10A cells, the ILs were found to be …

Syrian Perspectives On The U.S. Intervention Against Isis: Analysis Of Youtube Videos, Nelson Cleveland

Honors Theses

This thesis investigates Syrian public opinion surrounding the 2014 U.S.-led military intervention against ISIS through critical discourse analysis of Arabic-language YouTube videos. In light of the renewed interest and continued presence of U.S. troops in Syria following the Assad regime’s collapse in 2024, the study examines how Syrians originally responded to the coalition strikes and political context in which they occurred. Drawing on four primary videos including street interviews, protest recordings, and discussions from expert panelists, the analysis uncovers recurring themes of distrust towards the U.S. and other states who engaged in intervention, condemnation of perceived collusion and exploitation, and …

Do Psychopathic Traits Influence Post-Traumatic Growth? Testing The Moderating Effects Of Psychopathic Traits Between Stressful Life Events And Post-Traumatic Growth, Ariela Denham

Honors Theses

The present study investigated the relationship between psychopathic traits and post-traumatic growth (PTG) following exposure to stressful life events. A sample of 291 undergraduate students completed self-report measures including the Triarchic Psychopathy Measure (TriPM), Post-Traumatic Growth Inventory (PTGI), and the Life Events Checklist for DSM-5 (LEC-5). Pearson correlations and hierarchical regression analyses were conducted to test whether the TriPM dimensions—Boldness, Meanness, and Disinhibition—moderated the association between stressful life events and PTG. Results revealed that Meanness was negatively associated with PTG, while Boldness and Disinhibition were not significantly related. Boldness showed a positive relationship with the PTGI Strength subscale, suggesting a …

Juntos, Tori N. Saenz

Honors Theses

Juntos is a sculptural exploration of interconnectedness and dependence between people. Throughout my life and travels around the world as a solo backpacker, I have seen firsthand how the human desire for connection transcends language barriers, personality differences, and various belief systems. This natural tendency to form relationships and depend on each other is integral to our society and our lives. In juntos, which means “together” in Spanish, I explore these human connections through figurative sculptures using abstraction, repetition, diversity, and balance.

The simple, abstract figures that make up juntos capture the internal composition of a person rather than …

Fear Of Pain In Migraine: Psychological Factors In Perceptions Of Headache Triggers, Sarah Basha, Todd Smitherman

Honors Theses

Migraine is a debilitating neurological disorder affecting millions worldwide, with substantial societal and personal burdens. Psychological factors, particularly fear of pain, may influence migraine experience by impacting perceptions of headache triggers. This study investigates the relationship between fear of pain and perceived triggers in individuals with migraine. A sample of 2,959 young adults meeting diagnostic criteria for migraine completed a structured diagnostic interview and self-report measures of fear of pain, headache-related disability, and beliefs about headache triggers (which stimuli triggered headache, most important triggers, and likelihood of developing a headache upon exposure to the most important trigger [trigger potency]). Linear …