Digital Commons Network^™

Synthesis And Characterization Of Rhenium 2,2′-Pyridylnaphthyridine Metal Complexes, Benjamin F. Solomon

Honors Theses

Rhenium (Re) is a group 7 heavy 5d transition metal in the same family as manganese (Mn) and technetium (Tc). Re-carbonyl complexes are known to be catalysts for many different kinds of reactions from C-C bond formation to reduction reactions like CO₂ reduction (CO₂RR)^1,2. With this in mind, we have prepared a set of six Re-carbonyl complexes of 2,2′-pyridyl-1,6-naphthyridine (1,6- pynap) and 2,2′-pyridyl-1,8-naphthyridine (1,8-pynap), a redox non-innocent ligand containing a bpy moiety as well as an additional aryl nitrogen binding location at which another metal-ligand bond could form. We have synthesized these complexes as precursors …

“... I Thought You Were Black .” An Autoethnographic Exploration Of The Fragmentation Of Identity And Culture., Sherley Arias-Pimentel

Honors Theses

"If anthropology doesn't break your heart, then you're not doing it right." - Ruth Behar Writing this thesis has been a trying experience. Within these pages, you will find the therapeutic expedition of a caramel-colored, Spanish-speaking, second-generation black Dominican woman from Newark, NJ who took advantage of this research opportunity to better understand the racial and ethnic parts of her identity which have caused her much turmoil and low self-esteem. Centering myself, my identity, and my story in this research and grappling with the complexities of the subject matter has been an exhausting yet liberating experience. I have contemplated many …

Do Traits Of Autism Spectrum Disorder In The Typically Developing Population Relate To Early Face Processing As Measured By The N170 And N250 Neural Signals?, Anna Murdock

Honors Theses

This exploratory study used electrophysiology to examine whether traits associated with autism spectrum disorder (ASD) in the typically developing population are related to early face processing. Previous literature has found mixed results about whether event-related potential (ERP) components appear differently in people with ASD, but two components that might be related to the observed deficit in face processing are the N170 component, which reflects the structural encoding of faces, and the N250 component, which reflects the individuation of faces. The present study analyzed data collected as part of the PURSUE EEG database. As part of the database, participants completed the …

Electrochemical Reduction Of Carbon Dioxide Using Ruthenium And Amines, Sydney Moise

Honors Theses

With an increased concern for climate change in the recent years, a significant area of research has been devoted to the reduction of greenhouse gases. Carbon dioxide (CO2) resides in the atmosphere between 300 – 1000 years, making the reduction of the molecule a substantial field of study.1 Amines have been used as CO2 scrubbing agents in literature historically, due to their ability to form bonds to carbon.2 Although studies involving metal catalysts and amines have been reported numerous times, research involving chemical reduction of CO2 using purely amines is scarce. In this paper, amines, in addition to hydride donors …

The Effects Of Positive Anticipation On Optimistic Cognitive Bias And Emotional Resilience In Rats, Megan Hooper

Honors Theses

The anticipation of positive events and optimism have been shown to improve health and emotional states in rats and humans. The current study is interested in the impact of positive anticipation on optimistic cognitive bias and emotional resilience, as well as neural markers of resilience. Male (n = 12) and female (n = 12) rats were assigned to either unpredictable positive expectancy response (UPER) training or the control (CON) group (n = 6 per group). Optimism was assessed using an ambiguous cue test (ACT) in which the rats were trained to associate a specific visual pattern with a high-value (Froot …

Role Of Cdx4 And Sp5l In Zebrafish Development, Wesley Tsai

Honors Theses

The Caudal Type Homeobox transcription factors cdx are a family of genes found in vertebrates that regulates body regionalization and anterior-posterior patterning. They are also responsible for regulating axial elongation, but the mechanisms behind this behavior are not known. Previous studies in mouse embryonic stem cells have shown that the cdx genes are necessary for upregulating the gene sp5 which may be linked to axial elongation. Sp5 is a zinc-finger transcription factor belonging to the specificity protein (sp) family. Our group has used in-situ hybridization experiments on zebrafish embryos to show that sp5-like (sp5l) is transcribed within tailbud tissues that …

Bryophytes Of Goochland County, Virginia, Mikayla Quinn

Honors Theses

Bryophytes are non-vascular land plants that include mosses, liverworts, and hornworts. Although easier to overlook because of their smaller size, bryophytes are a fundamental part of the ecosystem. As such, maintaining record of their biodiversity is important. Yet, records of bryophyte species in Goochland County, VA were low compared to more thoroughly documented counties such as Prince Edward County. This study expands the documentation of bryophyte flora and presents a checklist of bryophyte species found Virginia’s Goochland County from 2020-2023. Fieldwork conducted at public and privately-owned properties throughout the county between January 2020 and March 2023 yielded 702 specimens that …

Investigating Myosin Ensemble Force Generation Using Optical Tweezers, Janie Watts

Honors Theses

Myosin is a motor protein that facilitates muscle contraction and movement by stepping along actin filaments using energy from ATP hydrolysis. If myosin or other motors are disrupted throughout the body, it can have many harmful effects. Hypertrophic cardiomyopathy is a disease caused by gene mutations that affect myosin heavy chains in the heart. The tissue of the heart becomes abnormally thick, which can make it more difficult to pump blood or block blood flow out of the heart. Our goal is to discern the mechanistic difference function of a healthy and diseased heart. To accomplish this, we construct model …

The Project That Claire, Uh I Mean The Student Completed: Relative Clauses And Repair Disfluencies, Claire O’Shaughnessy

Honors Theses

Several areas of psycholinguistics focus on the role of memory in language processing. Two of these areas are repair disfluencies and complex syntactic structures; however, these two topics have traditionally been investigated completely separately from one another. The current experiment combines these two topics by presenting listeners with spoken sentences containing subject-extracted relative clauses (SRCs) and object-extracted relative clauses (ORCs) in which the semantic similarity between the critical noun phrases (NPs) was manipulated. In addition, the sentences could be spoken fluently, or there could be a repair disfluency in which the reparandum contained information that would be potentially helpful in …

Investigating The Helicase Activity Of Methylated Vs Unmethylated Ded1, Hannah Lukow

Honors Theses

Ded1 is an RNA helicase protein of the DEAD-box subfamily in eukaryotic organisms (Sharma & Jankowsky, 2014) which can act as an activator or initiation factor, during translation (Hilliker et al., 2011). Ded1 has several functions in yeast including assembly of translational initiation factors, scanning the mRNA for the start codon, and unwinding any double stranded segments of mRNA with its helicase ability. Ded1 was discovered to be methylated at four arginine sites in vivo (Low et al., 2013), with a fifth methylation site being discovered recently (Low et al., 2020), however the purpose of such post-translational modifications is still …

Analysis Of Wild Rodent Gut Microbiota As A Function Of Exposure To Ticks And Tick-Borne Pathogens, Joshua Pandian

Honors Theses

Due to advances in high-throughput parallel sequencing, researchers have conducted novel studies exploring relationships between microbiome compositions and different aspects of organism health. Some of these studies have shown that the gut microbiome of rodent models has effects on organism health and behavior and that infection with pathogens and the composition of the skin microbiome are linked to changes in gut microbiome composition. While previous studies have shown how vector microbiota impact vector behavior and pathogen transmission, the effect vectors have on reservoir species microbiomes has been a less prominent focus. We were interested in the relationships between tick parasitism, …

Pharmacists’ Perceptions And Knowledge Of The Legalization Of Medical Marijuana In Mississippi, Faith Houston

Honors Theses

The legalization of medical cannabis in Mississippi was a debated topic among all citizens. This thesis specifically explored pharmacists’ perceptions and knowledge as medical professionals who will be involved with patients certified to use medical cannabis. Information was gathered using a voluntary online survey on the Qualtrics platform to produce a cross-sectional, descriptive study.

From the information gathered, it was apparent that pharmacists in Mississippi have varying opinions regarding medical marijuana. Some are in favor of using these products, and some are not. However, as cannabis has been officially accepted and put into patient's medical plans both current and future …

Breaking The Academic Lockstep: Dr. Samuel Clark And The Birth Of Honors Education At Western Michigan University, Tashfia Raisa

Honors Theses

The Lee Honors College at Western Michigan University has grown so rapidly over the past few decades that one may overlook its humble beginnings. The first Director of the Honors College, Dr. Samuel Clark, contributed greatly to the establishment of the college and the development of the curriculum. This thesis, which examines the origin of honors programming nationally and at Western Michigan University, will allow future researchers and administrators to better appreciate today’s honors program at Western Michigan University in light of its past.

The Influence Of Motivation To Control Prejudice On Facial Processing Flexibility In Individuals Who Identify As Biracial, Chloë Steckart

Honors Theses

Facial processing is one of the most important and immediate aspects of cognition (Jaeger, 2019; Kovács, 2020). Race is an extremely salient facial processing cue that has immediate and long-term impacts on how we interact with others (Oosterhof & Todorov, 2008; Senholzi & Ito, 2013; Blascovich et al., 2017; Kawakami et al., 2022). Race is a powerful in-group in American contexts, and race cues in facial processing play a part in determining in- and out-group members (Tropp & Wright, 2001; Castano et al., 2002).

We investigated how race impacts the facial processing of individuals who identify as Biracial and whether, …

Veiled Victorian Vampires: What Literary Antagonists Reveal About Societal Fears Of 19th Century England, Jenna Harford

Honors Theses

In my thesis paper I look at three primary texts, Charlotte Brontë’s Jane Eyre, Charles Dickens’ Great Expectations, and Oscar Wilde’s The Picture of Dorian Gray to analyze their main antagonists through a vampiric lens. I explain how the characters of Bertha Mason, Miss Havisham, and Dorian Gray are all written with veiled vampiric traits that revolve around themes of sexuality, secrecy and seclusion, and unbridled physical and emotional violence. Although none of these texts is obviously a “vampire novel”, the authors lean into vampire tropes including eerie physical description, doubled relationships, and other vampire lore that can be best …

The Role Of Cerium(Iii) In Bacterial Growth And The Microbial Transformation Of Aromatic Hydrocarbons, Shruti Sathish

Honors Theses

Biofilms are communities of surface-attached bacterial cells encased in an exopolymeric matrix. In this state, they are more resistant to antimicrobial treatment and can have adverse effects in medical, agricultural, and industrial settings. Whereas, as biocatalysts, biofilms from nonpathogenic bacteria enhance their performance and stability in catalysis. Unfortunately, there are several challenges when using bacteria in organic transformations due to their complex cellular chemistry. Trivalent lanthanide metals were discovered to serve regulatory roles in some bacterial catalytic processes, including those of Pseudomonas putida KT2440 (P. putida), a non-infectious Gram-negative bacterium. The main goal of our research is to use cerium(III) …

Of All That Continues To Change, Elizabeth Mckenzie

Honors Theses

I am researching the concept of metamorphosis as a reflection of myself and my journey for this Graduating Presentation project. I will be exploring the different components that influence this process of change and growth. Through my process I will inquire “What is necessary for this drastic evolution to occur, and what ideas must be present for it to follow through?” For this project, I will choreograph a staged work comprised of about 7-10 dancers (and understudies). I plan to take the audience through the ups, downs, and influences involved in the process of metamorphosis.

In order to experience growth …

Study Budgets In Human Anatomy And Physiology Students: Assessments Of Time On Tasks As Affected By Student Motivation And Assessment Weighting, Mattie C. Derivaux

Honors Theses

The extent to which a student is motivated, along with the root of that motivation, can significantly influence the nature of a student’s experience in a course, especially in a rigorous science course such as Human Anatomy and Physiology (HAP). Students’ perceptions of specific course elements, coupled with how they perceive their purposes, can alter their motivation to succeed, which in turn can affect their performance. This study sought to analyze student motivation in an undergraduate HAP course at the University of Mississippi by focusing on students’ attitudes towards the weight distribution of course assessments, effort exertions, and time allotted …

The Effect Of Youth Sports Participation On Health Outcomes For Immigrants In The United States, Emma Kennedy

Honors Theses

My study investigates the relationship between youth sports participation and health outcomes for immigrants using a quantitative statistical analysis of secondary data. Given the theory behind the relationships between physical activity level, sense of community, and health outcomes, I test the hypothesis that immigrants are positively impacted by youth sports participation on a significantly higher level compared to non-immigrants. Using Stata as my statistical analysis software tool, I measure the associations between immigrant status, sports participation, and various indicators of health such as BMI and reports of chronic illness. I found that sports participation is associated with improved general health …

Assessing The Dynamic Amongst Self-Compassion, Connection To Nature, And Well-Being, Yueyi Fan

Honors Theses

In 2015, the United Nations deemed promoting individual well-being of paramount importance, along with seventeen other sustainable development goals (to be achieved by 2030). Unfortunately, overall mental health has taken sharp declines with the unprecedented onset of the COVID-19 pandemic (OECD, 2021). According to a report from the Organization for Economic Cooperation and Development (OECD), the prevalence of anxiety and depression has increased globally; it has doubled or more than doubled as compared to previous years (OECD, 2021). The Centers for Disease Control and Prevention (CDC) has reported increasing levels of adverse mental health conditions, substance use, and suicidal …

Allowing And Using Low Nutritional Value Foods For Celebrations, Rewards, And Motivators In K-12 School Classrooms: Teacher Candidates’ Beliefs At The University Of Mississippi, Chandler Cohn

Honors Theses

Objective: Identify University of Mississippi teacher candidates’ beliefs and observations about offering low nutritional value foods for student events from their K-12 school placements.

Methods: A twenty-two-item, cross-sectional survey was developed with Qualtrics based on the Theory of Planned Behavior. The survey was distributed to juniors and seniors at the University of Mississippi, with a response rate of 79%.

Results: A majority of teacher candidates (69%) observed that their clinical instructor currently uses low nutritional value foods in the classroom to reward academic achievements, while only 38% agree that this is the right decision.

Conclusions and Implications: A greater focus …

Literature Replication: Insect Gut Cell Isolation Protocols, Sophie Pickelner

Honors Theses

A large problem in science is the lack of literature replication, especially for subjects in which there is little published research. Literature replication is an integral part of the scientific method and is important for validating methods and results of published studies. A study from Nature found that out of 1,500 scientists interviewed, over 70% have been unable to reproduce literature studies and over half of them have been unable to reproduce even their own studies (Baker, 2016). This problem is even more pronounced in the field of biology, with 80% of scientists reporting that they are unable to replicate …

Capturing The Racial Identities Of Latiné Students At A Mid-Size Texas University, Marlena Sandoval

Honors Theses

No abstract provided.

From Big Farm To Big Pharma: A Differential Equations Model Of Antibiotic-Resistant Salmonella In Industrial Poultry Populations, Rilyn Mckallip

Honors Theses

Antibiotics are used in poultry production as prophylaxis, curative treatment, and growth promotion. The first use is as prophylaxis, or prevention of common bacterial diseases. The crowded conditions in concentrated animal feeding operations necessitate management of infectious disease to ensure overall animal health and the profitability of such operations. In these farms, between 20,000 and 125,000 birds are raised in shed-like enclosures [3], with an average of less than one square foot of space per chicken [34]. Antibiotics are currently used in chicken farms to manage and prevent common bacterial diseases such as respiratory and digestive tract infections, as well …

Case Study Summary: Johnson & Johnson And Macy's Inc., Cameron Richardson

Honors Theses

This thesis, over a one-year period, covers conclusions derived from research on two different companies: Johnson & Johnson and Macy’s Inc. Through a two-semester course taken within the scope of the honors college alongside Dr. Victoria Dickinson, I, alongside my respective group members for each company, were able to compile a thorough analysis of risks and business strategies the two corporations could identify and implement to manage present and future complications. This analysis followed standard conventions of the accounting profession, as our research was focused on identifying risks and strategies affiliated with audit, tax, and advisory services, modeling how professional …

Anti-Microbial Peptide Screen For Crop Protection, Sydney Chen

Honors Theses

Vestaron currently uses an established and reliable peptide discovery and development research platform, particularly for the development of insecticidal peptides. The platform centers around a proprietary yeast expression system for peptide production (“Vestaron’s yeast expression system"). Vestaron aims to expand their portfolio and provide clean solutions in crop protection using peptide technologies to protect plants not only from insect pests but also microbial pests including phytopathogenic fungi and bacteria. Antimicrobial peptides (AMPs) have been studied extensively. However, it is questionable whether Vestaron’s yeast expression system can express AMPs heterologously. In this study, thirteen promising antimicrobial peptides were selected from literature …

Race, Gender And Rawls' "A Theory Of Justice.", Robert Carico

Honors Theses

Should we use the concepts developed by John Rawls in his A Theory of Justice to guide research questions relevant to issues concerning race and gender? This paper argues not only that the concepts from A Theory of Justice should not be used as the primary tool in any debate concerning race and gender, but it also challenges the abstract thinking of 21st Century Western Philosophers to develop a theory of justice that acknowledges the fact that people have their own interests and depending on what race and/or gender they identify with, might not have equal rights protected under the …

Computational Study Of The Rotational Barrier In Indole Derivatives, Javaughn Martinez

Honors Theses

The purpose of this computational study is to understand the rotational barrier in indole derivatives, leading to stereoisomers, specifically atropisomers, which will impact the research direction focused on the development of a porphyrin hosts in Professor Starnes’s group. The Starnes research group is working to synthesize a porphyrin host that can function as a sensor or to remove harmful and deleterious anions such as phosphate and nitrates (Busschaert, et al, 2015). We will utilize the data provided to understand the required energy to restrict a rotation around the indole-benzene bond. To do so, the indole derivatives will be studied using …

A Review Of Pre-Clinical Studies On Meth-Induced Gut Microbiome Alterations, Payton Brabant

Honors Theses

Substance use disorder (SUD) is a chronic, pervasive disease that affects approximately 40.3 million people aged 12 and over within the United States (SAMHSA, 2021). Recent investigations have emphasized preventive measures targeting the development of SUDs and the occurrence of relapse. However, to date, FDA-approved medications are only available for those with alcohol (AUD) and opioid use disorders (OUD) (Forouzan et al., 2021). Given that about 964,000 people have methamphetamine use disorder (MUD) within the United States, investigation of novel treatment approaches for psychostimulant abuse is warranted (Forouzan, Hoffman, and Kosten, 2020). Several negative effects can occur after using methamphetamine …

Blood Flow Restriction Therapy As A Treatment In Rehabilitation, Sara Barr

Honors Theses

Blood flow restriction therapy, also known as BFR, is a treatment that is gaining popularity in the realm of rehabilitation and personal fitness. Commonly, BFR is used along with resistance training in physical therapy clinics for patients post-surgically, post injury, and for general muscle weakness (Congetti et al., 2022). BFR utilizes occlusion and pooling of blood, along with triggering the physiological processes of resistance training to decrease the hypertrophic threshold of a muscle (Congetti et al., 2022). This literature review aims to investigate the effects of BFR on patients in physical therapy after surgery by examining the history and origin …