Digital Commons Network^™

Evaluation Of Blight Resistance In Chestnut F2 Half-Sibling And Full-Sibling Families Via Small Stem Assay, Kevin Gentner

Honors Theses

In 1904, Cryphonectria parasitica, the causal agent for chestnut blight, was imported into North America on chestnut nursery stock from China. Fifty-five years later, nearly all full-grown wild American chestnut trees (Castanea dentata) were dead. A century of work has been put into restoring the American chestnut to its rightful place among the forest canopy. Since the 1980s, The American Chestnut Foundation has pursued backcross breeding to introgress blight resistance into C. dentata from the resistant Chinese species (C. mollissima), and has used progeny testing to make predictions about parental resistance in B3F2 chestnuts. We performed a small stem assay …

American Foreign Policy Has A Masculinity Problem: A Discourse Analysis Of The Iran Deal, Rachel Emond

Honors Theses

The research in this paper seeks to analyze the rhetoric surrounding issues of American foreign policy using the Iran Deal as a case study. The main question this research intends to answer is: Are suggested soft power policy solutions, such as that of the Iran Deal, characterized as either feminine or masculine? I seek to answer this question through a discourse analysis of the rhetoric in newspaper articles from The New York Times and The Washington Post about the Iran Deal from the year 2015. I identify common themes and phrases among these articles and draw my own conclusions about …

Culture, Food, And Racism: The Effects On African American Health, Kalah Elantra Vance

Honors Theses

Cultures can be influenced by a number of different factors, one of the most notable being food. Cultural food staples have often traveled from their country of origin of to be integrated into the cuisine of another. African slaves for example, used their knowledge of their West African heritage to forage soul food, a well know cuisine in the American South. The adaptations made to food practices during slavery decreased the nutritional value of the previously healthy West African dishes. After creating a relatively unhealthy food culture through slavery, African Americans continued to face persecution at the hands of the …

An In Vitro Analysis Of The Relative Efficacies Of Antibiotic Solutions Vs. Antiseptics In Breast Augmentation And Reconstruction Surgery, Victoria Noyes

Honors Theses

Breast augmentation and reconstruction procedures are among the most popular plastic surgeries in the U.S. Opportunistic bacterial pathogens introduced during surgery can lead to surgical site infections, capsular contractures, biofilm formation, and lymphoma. To prevent these infections, an antibiotic solution containing Cefazolin, Gentamicin, and Bacitracin (Adams’ Antibiotic Solution - AS) has traditionally been used for irrigation. Due to antibiotic resistant pathogens and a debate over the efficacy of irrigation by AS to reduce infections, alternatives must be found. This study considers the use of the antiseptic chlorhexidine gluconate (CHG) as an alternative irrigation solution. In vitro, we exposed pure cultures …

Tanapox: A Potential Oncolytic Virus For The Treatment Of Cancer, Joel Marty

Honors Theses

The National Cancer Institute defines cancer as a group of related diseases characterized by unimpeded cell division with metastatic abilities. Cells frequently mutate and potentially become cancerous, but generally these cells are cleared by the immune system. The disease state of cancer arises when the mutated cells evade the immune clearance, which indicates medical intervention is required. Current therapies most commonly utilize chemotherapy, radiation, or a combination of the two, however, alternative therapies are being developed such as immunotherapies and oncolytic viruses (OVs). OVs cause a viral infection, clearing cancerous cells through viral replication mechanisms, such as viral cytolysis, while …

Examining The Effect Of Perseverative Thinking On Physiological Activation In Response To Stress, Kathleen Kelly

Honors Theses

The current study had two aims: (1) measure changes in heart rate variability from the time of learning about a stressor task to completion of the task and (2) measuring the change in heart rate during and after the stressor task. Thirty participants were recruited from a midwestern university campus as well as surrounding communities. The study utilized a laboratory based stressor to examine the influence of perseverative thinking on stress recovery over a 24-hour period. Participants were involved in the study for a continuous 48 hours that included three lab visits. Participants’ activities and heart rates were measured through …

17Β-Estradiol In Carbondale Treated Wastewater Effluent: A Cross Comparison Study, Evan Mcdermott

Honors Theses

Natural estrogens are endocrine disrupting compounds and common pollutants in municipal wastewater. The concentration of 17β-estradiol was monitored in effluent from both the southeast and northwest Carbondale wastewater treatment plants (WWTPs) and their receiving waters for nine weeks. The analysis was performed using gas chromatography tandem mass spectrometry (GC/MS/MS) and the internal standard estrone 3-methyl ether. Recoveries were 60.0±3.9%, and significant loss of analyte was found after storage greater than one week. The northwest effluent (NWE) had higher 17β-estradiol levels of 7.1-76.2ng/L than the southeast effluent (SEE) between Below Detection Limits (BDL)-54.0ng/L, which suggests 17β-estradiol was carried with colloidal organic …

It Is Always Worth It To Check It Again: Examining Nematodes Of Rodents From The Konza Prairie, Hailey Penticoff

Honors Theses

The Konza Prairie Long-Term Ecological Research (LTER) is centered on the 3,487-hectare tallgrass Konza Prairie in eastern Kansas. The area supports 11 common species of rodents, some of which are reservoirs of zoonotic microparasites, including etiological agents for babesiosis and Lyme disease. Furthermore, each of the rodent species harbors an array of helminths. No baseline inventories of helminths or microparasites have yet been performed through the tallgrass prairie ecoregion. We captured rodents using Sherman traps, processed them via standard museum methods, and examined them for nematodes. Necropsies were completed on the same day of capture and nematodes collected were fixed …

Sensory Processing Disorder: A Design Research Report, Ashley Booth

Honors Theses

No abstract provided.

Geochemistry Of Surface Waters And Groundwater At Eku’S Meadowbrook Farm, Madison County, Kentucky, Reid E. Buskirk

Honors Theses

Agricultural activities often contaminate watersheds with excess nutrients leading to poor water quality and eutrophication. Eastern Kentucky University (EKU) Meadowbrook Farm raises crops and livestock, which contribute dissolved nutrients to the neighboring Muddy Creek watershed. Our goal is to understand Farm water geochemistry to develop methods to sequester phosphorous and limit nutrient contamination.

During the Cindy storm event, concentration of Ca²⁺, Mg²⁺, and Na⁺ within baseline source waters decreased with increasing discharge through the weir. This behavior represents dilution of Farm groundwater by storm precipitation. However, K⁺ spiked concurrently with increased discharge then progressively …

Initial Characterization Of The Two Clpp Protease Isoforms From Chlamydia Trachomatis, Krystal Chung

Honors Theses

Chlamydia trachomatis is an obligate intracellular bacterial pathogen responsible for sexually transmitted infections and the ocular infection trachoma. Chlamydia undergo a distinctive developmental cycle transitioning between the infectious elementary body form and the replicative reticulate body form. Each developmental form has a distinct proteome reflecting its different physiological needs. We are interested in studying how protein degradation impacts proteomic patterns throughout the developmental cycle. Chlamydia encode a pan-bacterial Clp protease system consisting of five genes: clpX, clpC, two clpP paralogs (P1 and P2), and clpB. ClpX and ClpC are chaperone proteins that unfold protein substrates and feed …

The Impact Of Transnational Nonprofit Work On The Development Of Becoming A Global Citizen, Penny Bowser

Honors Theses

Global citizens dive into the culture of a country and adopt new ideology, customs, and traditions, while maintaining their own cultural identity. This paper explores how a nonprofit organization has the ability to provide the necessary resources for a volunteer to expand upon their global citizenry. Nonprofits were created for economic, historical, and professional reasons, then are divided into categories depending upon the goal of the organization. Volunteers choose to serve at nonprofits for social, personal, and professional reasons, but will all make an impact on the people they are serving, despite the reason. By volunteering with a transnational nonprofit …

Increasing Awareness Of International Adoption Through Literature, Romy Newberry

Honors Theses

No abstract provided.

On The Feasibility Of Using Genetic Algorithms To Optimize The Structure Of Small Multilayer Perceptrons, Nicholas Dinep-Schneider

Honors Theses

Artificial neural networks, which mimic the human brain's ability to learn from experiences, are increasingly being used to analyze complex datasets. However, proper structural configuration requires intuition, trial-and-error, and frequent human attention. This study investigates an automated alternative that uses a Darwinian evolutionary strategy to optimize the structure of a small-scale Modified National Institute of Standards and Technology (MNIST) image classification network. Using accuracy as a measure of fitness, it examines the effect of varying the amount each network learns prior to differential reproduction. The accuracy of optimized networks was significantly higher than random initial networks, being increased by up …

A Mathematical Model For Inhibitor Drugs In The Treatment Of Alzheimer's Disease, Richard Young Leonard Iii

Honors Theses

Recent studies reveal that from the pathological standpoint, Alzheimer’s disease (AD) is described by the cerebral deposition of aggregated amyloid beta (AB) polymers in the form of amyloid plaques. This thesis introduces a new mathematical model for the treatment of AD in the presence of inhibitory drugs. Two types of drugs are considered: monomer inhibitors of AB aggregation and anti-aggregate drugs. First, the model is analyzed with only one of the two drugs and then the two drugs are tested in the presence of one another. The numerical simulations of models show that the first type of drug is able …

Implementing Early Screening Methods To Detect Resistance To Phytophthora Cinnamomi In Backcross Chinese-American Chestnut Hybrids, Kirsten Hein

Honors Theses

Phytophthora root rot (PRR), caused by the oomycete Phytophthora cinnamomi Rands., is one of the two greatest obstacles to survival of American chestnut (Castanea dentata Borkh.). The other is chestnut blight, caused by the ascomycete Cryphonectria parasitica (Murr.) Barr. Developing early and reliable PRR screening methods can facilitate the efficient introgression of PRR resistance from Chinese chestnut (C. mollissima Blume.) into the populations of potentially chestnut blight resistant trees currently under development by The American Chestnut Foundation (TACF). This study tests the efficacy of a method for early identification of PRR-resistant hybrid chestnuts in a greenhouse/nursery setting. The chestnut blight …

Characterization Of Metamorphic Zones In The Tennessee Blue Ridge Using Gis And Digital Imaging Processing, Hayley Beitel

Honors Theses

The origin of metamorphic zones of the Blue Ridge is attributed to metamorphic events that affected sedimentary rocks of debated age, leading the topic to be controversial and continuously studied. The present study seeks to refine the metamorphic isograds of the Tennessee Blue Ridge based on Barrovian index minerals in pelitic rocks and the texture patterns these pelitic rocks present. Methods used in the present study are supported by conventional petrography, powder X-ray diffraction, and by GIS and digital image processing. Metamorphic isograds in the Blue Ridge have been determined mainly by identification of index minerals using a polarizing petrographic …

Molecular Monitoring Of Methicillin-Resistant Staphylococcus Aureus (Mrsa) In A Hospital Setting, Jessica Ammon

Honors Theses

Methicillin resistant Staphylococcus aureus (MRSA) is a potentially pathogenic bacterium that poses a serious risk in healthcare settings. MRSA can be characterized by a genetic element, known as the staphylococcal cassette chromosome, which harbors the gene responsible for methicillin resistance, mecA. MRSA can be classified into two categories: community acquired (CA) and hospital acquired (HA). S. aureus strains represent a major health concern due to their prevalence in healthcare facilities and their rapidly evolving antibiotic resistance. The current study investigated the association between MRSA isolates obtained from patients and from the intensive care units in a local hospital. Among the …

The Effects Of Skin Tone On The Perception Of Discrimination In Young African American Women, Danielle T. Stamps

Honors Theses

This research focuses on the perceived discriminatory experiences (i.e. colorism and racism) that young African American women report as a function of their actual and perceived skin tone. Colorism is a form of internalized racism when individuals with darker skin tones are discriminated against by others. Each participant (N = 76) was given the Pantone Skin Tone guide and asked to find the best color (varying on undertone and lightness) that matched closely to their skin tone without feedback from any reflective surfaces and with a handheld mirror. Following that, the researcher identified the participant’s skin tone. In addition, participants …

An Exploration Of Pyrrole Groups On The Enantioselectivity Of Pig Liver Esterase, Brian Long

Honors Theses

Pig Liver Esterase (PLE) is a serine protease enzyme that can interact with one side of a diester to hydrolyze the ester to a carboxylic acid, and research has found that the level of hydrophobicity of side groups can impact the enantioselectivity of PLE hydrolysis.1, 2 The Jones Model is what current researchers use to model the active site of PLE, but the nature of its binding pockets, namely the Hydrophobic Long (HL) pocket, has been called into question.3 Dimethyl 2-((pyrrole-2-yl)methyl)-2-methylmalonate was prepared to be subjected to PLE hydrolysis to see whether enantioselectivity was found. Chiral HPLC revealed 25.32% enantiomeric …

Pro-Antimicrobial Networks Prepared Via Degradable Thiol-Ene Acetal Photopolymerization, Sarah Swilley

Honors Theses

A degradable, antimicrobial polymer network with acetal crosslink junctions derived from p-anisaldehyde (pA), a common constituent found in star anise extract, is reported. The p-anisaldehyde was converted into a bis-functional acetal alkene monomer, which serves as a pro-antimicrobial form of the active aldehyde and a building block for materials referred to as pro-antimicrobial polymer networks via degradable acetals (PANDAs). Subsequently, the bis-functional acetal alkene monomer was photopolymerized with a multifunctional thiol to yield a thiol-ene network. PANDAs exhibit surface erosion behavior and yield sustained release of pA over 38 days when exposed to neutral or biologically relevant conditions. The pA …

Using Pattern Area Ridge Flow In The Three Areas Of The Palm To Determine Classification Trends, Ashton Horton

Honors Theses

Friction ridge skin is only located on the fingers, palms, and soles of feet. These ridges have been used to make identifications since before the twentieth century. These methods may be the basis of scientific testimony in court because of the amount of research that has been conducted in fingerprint identification. Courts uphold these techniques because of three principles behind fingerprint identification: fingerprints are unique because no two are the same, they will not change from the time they are formed in the womb until post-mortem decomposition, and they can be objectively classified using a general classification system. Little research …

Effects Of Acorns On Populations Of Aedes Mosquitoes, Rachel Rogers

Honors Theses

Aedes albopictus (Asian tiger mosquito) and Aedes aegypti (yellow fever mosquito) are two mosquito species that are non-native to North America and are of medical importance. Both species can be found in aquatic container habitats, such as discarded tires and tree holes. In container habitats, the influx of detritus from the outside environment is essential to mosquito production and can include a variety of plant and animal material. Seeds from oak trees (acorns) can seasonally contribute to the detritus of these container habitats. This study examined the effect of acorns from the southern live oak (Quercus virginiana) on the performance …

Lead, Copper, And Iron In University Tap Water, Alison Mclendon

Honors Theses

This study observed concentrations of lead, copper, and iron in university tap water over an eight-week span during and between the summer and fall semesters. First draw and 30s flush samples were taken after overnight stagnation from the Honor House, College Hall, J. B. George Building, and International Center bathrooms and analyzed with an inductively-coupled plasma mass spectrometer (ICPMS). There was no obvious correlation between time in the semester and metal concentrations. Relative iron levels rose and fell at the same time in all buildings, but there was little correlation between buildings for lead and copper concentrations. The Honor House …

Thiol–Ene Photopolymerization: A Simple Route To Pro-Antimicrobial Networks Via Degradable Acetals (Pandas), William Martin

Honors Theses

The World Health Organization (WHO) has brought the growing epidemic of antibiotic resistance bacteria to the attention of the public and has expressed the need for the development of new methods of defense. In this direction, bioactive aldehyde essential oils have been shown to effectively act as antibiotic and antifungal agents. These bioactive compounds, when used in their pure form, are volatile and lack environmental stability. In this thesis, we describe the synthesis of pro-antimicrobial networks via degradable acetals (PANDAs) using thiol-ene photopolymerization. PANDAs were used as a new model for the high loading and release of bioactive aldehyde-containing compounds …

The Knowledge Of Sexually Transmitted Diseases Among College Students, Annie Doster

Honors Theses

The purpose of this study was to address the perceived and actual knowledge levels of sexually transmitted diseases (STDS) among college students at a southern university. The sample consisted of 138 participants over the age of 18 enrolled as undergraduate students at the University of Southern Mississippi (USM). A questionnaire was distributed via email listserv to the undergraduate population at USM assessing the attitudes and knowledge surrounding sexually transmitted diseases. The survey included three sections for the assessment of each variable: 12 demographic questions, 20 statements assessing student attitudes regarding the quality of their previous sex education and perceived knowledge, …

Distance And Sympathy In Public Argumentation On Hb 1523: Four Pastoral Letters Creating Value Frameworks, Jonathan Eugene Bridenbaker

Honors Theses

HB 1523, otherwise known as the Religious Liberty Accommodations Act, is Mississippi’s contribution to a larger national conversation surrounding the duty and obligation that states have to protecting individual liberty and freedom. Even further, though, lies a conversation about how rights and constitutional freedoms can be used to negatively harm and marginalize people on the basis of “freedom of speech” and, more specifically, “freedom of religion.” By examining four pastoral letters published by different Mississippi churches and religious bodies, I aim to show how both sides of this public debate are advancing themselves as the victims of some sort of …

Interactions Of Fire And Herbivory On The Management Of Ilex Glabra In Longleaf Pine Forests, Courtney R. Filliben

Honors Theses

The longleaf pine forest is characterized by the high levels of biodiversity and species richness that give it both ecological and economical importance. Decades of clear-cutting, habitat fragmentation, and natural fire restriction have reduced this once great forest system to a mere fraction of its original range. One of the specific causes of the decline of the longleaf pine is understory domination by woody shrubs. These shrubs limit the growth of characteristic grasses and forbs that are responsible for the majority of the biodiversity. The overall purpose of this study was to identify a new longleaf pine reforestation technique that …

Sibship Reconstruction For Inferring The Number Of Breeders Of Gulf Sturgeon In The Apalachicola River, Robbilyn Verges

Honors Theses

The Gulf sturgeon is an anadromous fish that inhabits the Gulf of Mexico and its neighboring river drainages. The species is currently listed as threatened due to habitat alterations and overfishing. In this study, we focused on the Apalachicola River in Florida, which has had several historic spawning locations of the sturgeon blocked by the Jim Woodruff Lock and Dam. Age-1 juvenile sturgeon from the year 2013 (n=31) and 2014 (n=131) were genotyped using fourteen microsatellite loci. Sibship reconstruction and parentage assignment was performed in order to determine the effective number of breeders (Nb) and the total number of spawning …

Naturalism And The New Woman: Fated Motherhood In Kate Chopin's The Awakening And Edith Wharton's The House Of Mirth, Lindsay J. Patorno

Honors Theses

Proto-feminist novels have garnered great critical attention in recent decades, largely owing to the reclamation efforts of feminist scholars from the 1960s onwards. These feminist scholars have remarked the fin-de-siècle emergence of a recurring narrative archetype: the unabashed New Woman, whose exploits in what were traditionally male-dominated spheres distinguished her from the domesticated matrons and sentimental bachelorettes of past literary paradigms. While the New Woman is now a commonplace among feminist critics, the following thesis uniquely interprets this feministic archetype in conjunction with the concurrent movement of American literary naturalism—a genre that proffers a deterministic worldview and is often regarded …