Digital Commons Network^™

Comparison Of Cardiac Muscle Between Male And Female Rats With Exercise And Aging: Analyzing Vitals, Gdnf Expression, Ngf Expression, Rna Expression, Sympathetic Innervation, Parasympathetic Innervation, And Sensory Innervation, Katelyn Kurrie

Honors Theses

The direction of my research-based thesis answers the question of how exercise affects the cardiovascular system with aging in male and female rats. My study would highlight the important differences of the cardiovascular system of both sexes which could lead to sex-specific insight on the cardiovascular disease epidemic which prevails as the most common cause of death in the United States. The studies completed will test the hypothesis: neurotrophic factor will be higher in females than males due to the higher presence of estrogen in females. The trophic factor is predicted to increase in both males and females with regular …

An Interdisciplinary Analysis Of Health Equity As Evaluated Through The Covid-19 Response Concerning French-Speaking Refugees., Margaret Henning

Honors Theses

A collaborative approach is needed to understand the multifaceted medical bias and inequalities experienced by refugee camps of Francophone (French-speaking) nations. A combination of interest and passion for anthropology, medicine, and the French language presents a unique window of intersectionality to analyze this issue. Through a comprehensive review of literature published in both English and French languages, and connections with directors and leaders of refugee camps located in France and French-speaking African nations, we have elucidated a few examples of alarming medical bias experienced by both refugees and migrants. Although an exhaustive list of medical bias could be presented on …

Development Of An Eci5 Group Iib Intron Mutagenesis System For Use In Chlamydia Trachomatis, Cassidy Evelyn Lounsbury

Honors Theses

No abstract provided.

Divorce, Academic Performance, And Attachment Styles In College Students, Pavllo Neco

Honors Theses

For years, social scientists have pondered the impacts of a parental divorce on the students’ academic performance, as well as their attachment style (Fomby, 2010). In the current study, it is hypothesized that students who experience a parental divorce will perform lower on academic performance and higher on the insecure attachment styles than students whose parents are still intact or remarried. Participants were 73 college students, ages ranging in age from 18-29. More than half of the study consisted of student’s ages 18-19 years. 65% of students who participated were female, and an overwhelming majority of participants were white, with …

Providing A Safe Space For Children Who Have Experienced Trauma, Alexis Garcia

Honors Theses

Health care professionals are continuing to learn about childhood trauma and the implications on health and development. With time, there has become a better understanding of how to determine and provide the resources needed for families and children who have experienced childhood trauma. Additionally, information about childhood trauma is slowly being understood throughout public school districts. This allows teachers to better understand children and accommodate their needs. This honors thesis will discuss childhood trauma and the development of a resource that can be used to provide elementary school-aged students with a place to go when they need assistance with regulation. …

Wmu Essential Studies Program: Creating Awareness For The New Required Curriculum, Catherine Lemus

Honors Theses

In the Fall semester of 2020, the WMU Essential Studies (WES) Program officially launched. This new program replaces the previous WMU General Education curriculum which was over 30 years old with curriculum concepts over 100 years old. While the WES program was not allocated any financial or human resources by Western Michigan University as its inception, it required assistance in creating messaging and content to help educate multiple audiences including current and prospective students, WMU faculty, WMU staff, and local community members. Catherine Lemus stepped in the role of WES Strategy and Marketing Assistant with the guidance of Prof. Greg …

An Examination Of Barriers And Determinates Impacting The Healthcare Of Kalamazoo County's Transgender And Non-Binary Young Adult Population, Tyler Signorella

Honors Theses

Historically non-binary and transgender individuals have faced and continue to face a unique set of obstacles and challenges in seeking and receiving general healthcare. Within the US this is well documented on a national level. In this exploratory study we will seek to understand the experience of young adults in Kalamazoo County comparing their perspectives to the already established pool of information. This will be accomplished through surveying emergent adults identifying as either transgender or gender non-binary within Kalamazoo County and then synthesizing this data into an analyzable collective format.

Out Of Mind: Undergraduate Predictors Of Generalized Anxiety Disorder Symptoms, Michael S. Lanzaro

Honors Theses

Demographic factors associated with anxiety have been studied extensively and are often characterized by interconnected relationships. These associations between variables provide insight into the predictive ability of anxiety in undergraduate populations. However, few studies if any have investigated the relationships between class level, sex, honors status, and undergraduate specialization as predictors of anxiety among an undergraduate American university sample. The results of this study provide key insight into the psychopathological development of undergraduate students and anxiety levels as it pertains to academic and demographic variables. By using a multiple linear regression analysis, demographic variables of American undergraduate students are compared …

Blenny Territoriality At Oyster Landing, North Inlet Estuary, South Carolina: Seasonal Patterns And Ecological Factors, Sydney Davis, Juliana Harding

Honors Theses

Temperate oyster reef blennies use oyster shells that are still articulated as habitat year round. During the breeding season when water temperatures are > 18-20°C, many species of blenny males use the oyster valves as nesting sites. Male blennies exhibit territorial behavior when guarding their nesting sites and can interact differently with conspecific and transient species. Striped blenny (Chasmodes bosquianus) and freckled blenny (Hypsoblennius ionthas) behavior was described from April 2020 to August 2020 at Oyster Landing, North Inlet estuary, South Carolina to quantify typical blenny behavior, general presence or absence of residents, and potential environmental parameters …

Infaunal Bivalve Density And Richness In North Inlet Estuary, South Carolina: Seasonal Patterns And Ecological Factors, Valerie M. Knowles, Juliana Harding

Honors Theses

Estuarine bivalves recruit to benthic habitats after the larvae are in the planktonic stage. The observed infaunal bivalve density relates to larval supply from adult reproduction during warmer months as well as larval and juvenile mortality post-recruitment. The purpose of this research was to examine annual and seasonal patterns of infaunal bivalve density and richness in the context of habitat water temperature and salinity. Cores were collected biweekly from Bly Creek in North Inlet estuary between January 2019 and February 2020. Temperatures ranged from 9-30 ºC and salinity ranged from ~17-36 psu. Bivalves were sieved out of the cores, counted, …

What's In A Name? An Assessment Of Degradation Of Women In The Name Of Climbing Routes, Raiza Barahona

Honors Theses

Gendered behavior is reinforced at an early age. In media, women are usually portrayed following gender stereotypical behaviors and are often sexualized, meaning that their worth is often determined by their body shape and clothing type and as such women are often wearing revealing clothing, following gender stereotypical behaviors, and portraying unrealistic body proportions (e.g., Gentlemen’s Quarterly Magazine; Collins, 2011). The representation of women in climbing media is similar to that of the general media. The present study focused on route names within the climbing community and presents a qualitative analysis on the sexism and other derogatory (i.e., overtly sexual) …

Improving Engineering Education Through Cyber-Physical Systems: Instrumentation And Control Of A Unit Operations Laboratory, Shelby Musselman

Honors Theses

A cyber-physical system (CPS) is a network of physical devices that are monitored or controlled by computer-based algorithms. A key enabler for future technology developments, CPS is an interdisciplinary research area that engages a broad spectrum of disciplines and could bring about revolutionary changes in domains such as energy, environment, and healthcare [1, 2] Using CPS to develop smart, connected products through hierarchies such as internet of things (IoT) allows for integration of systems and provides open access to data subsets for digital service applications. This technology has the potential to transform our everyday lives (e.g., smartphones, activity trackers), our …

The Design And Validation Of A Qpcr-Based Approach To Cell Quantification Of Fungal-Algal Symbioses, Isabelle Katherine Garlotte

Honors Theses

Symbiotic relationships are extremely common in virtually all species. These relationships between organisms, particularly mutualistic symbioses, can have an incredibly large impact and can greatly affect the evolution of the species involved. Of particular interest is the suspected mutualistic relationship between green algae and fungi that may hold key evidence of how terrestrial plants evolved. In this experiment we established a method of quantifying the cells of each species involved in these symbioses through qPCR analysis to determine if the relationships are truly mutualistic. We developed a system for using DNA copies as a proxy for cell count in co-cultures …

Search For Antibiotic-Producing Microorganisms In Sites Affected By Acid Mine Drainage, Hannah A. Bussell

Honors Theses

Antibiotic resistance in bacteria are an escalating problem. Little is known about the potential of microorganisms in sites affected by acid mine drainage (AMD) to be sources of new antibiotics. Sediments from AMD sites in Letcher County, Kentucky, were collected and microorganisms isolated. These samples were screened for their capacity to produce antimicrobial compounds active against known bacteria E. coli and S. aureus. The results showed no antimicrobial activity. This could be due to sample death, incorrect pH of media, or antibiotic resistance already present in the AMD site.

Lyme Disease In Kentucky: Prevalence, Awareness, And Diagnosis In A Conventionally Low-Endemic Area, Rachel L. Carden Ots

Honors Theses

Lyme Disease is the fastest-growing vector-borne illness in the United States – including in low-endemic states, such as Kentucky; given Kentucky’s low Lyme disease incidence in prior decades, it has since experienced an increase of cases despite a lack of discussion on the condition and its implications on patient health and wellbeing. To measure current levels of knowledge and awareness of Lyme disease in Kentucky residents, a survey was distributed to Microbiology and Honors Program students at Eastern Kentucky University, and its results were discussed. While Lyme disease cases do continue to rise, the general public of Kentucky lacks in …

A Topological Analysis Of Gene Co-Expression Networks From Brain Data, Mary Lee

Honors Theses

Gene expression data is a compilation of gene activity expressed in a certain tissue. This data has the potential to help uncover genes associated with some disease, stimulus, and treatment. The Allen Brain Atlas has made available gene expression data describing the activity of genes in individuals and tissues related to aging, dementia, traumatic brain injury, brain cancer, and many other brain-specific conditions. This project uses statistical and information-theoretic metrics like Pearson correlation and mutual information to build gene co-expression networks, which are represented by nodes on a graph that correspond to a gene. The nodes are connected when they …

Use Of Nanotechnology And Phytochemical Approaches To Investigate Boar Spermatozoa, Robyn E. Hadden

Honors Theses

Mass semen production for genetic conservation and large commercialization is considerably limited in the swine industry. Boar semen have specific features that prevent mid- and long-term preservation in cooling and freezing extenders, respectively. The success of long-term semen preservation in liquid nitrogen following deep-freezing, also known as cryopreservation, is drastically limited in swine farms. Meanwhile, the preservation of chilled extended boar semen has limitations due to the progressive decrease of sperm fertility potential during storage. With the ultimate goal of producing high quality semen for larger distribution, there is a need to investigate novel approaches to improve boar semen quality, …

Optimization Of Cation Exchange Chromatography Purification Of A Small Peptide: An Industrial And Practical Approach, Jamin Willoughby

Honors Theses

Ion exchange chromatography (IEX) is a common chemical separation technique that is used to separate ionizable target molecules from a liquid mixture mobile phase by adsorption of the molecule to a stationary phase. In chromatography, the stationary phase is a porous solid that the target molecule and mobile phase flows through, and is commonly referred to as the resin. Resins are commonly packed into hollow cylindrical columns. The mobile phase is the liquid solvent which flows through the column containing the stationary phase. The target molecule will have an affinity for the resin and adsorb to it, while impurities in …

“What Did You Say To Me?” – Social Feedback, Body Image, & Eating Disorders In Modern Day Society, Caitlin N. Mehs

Honors Theses

Eating disorders are one of the most lethal psychological disorders and need further insight into how they are developed. After an extensive literature review, I am proposing that social feedback influences body image, and body image influences eating disorders. It was predicted that there will be a strong, positive correlation between body image (as measured by body dissatisfaction) and eating disorders. It was also predicted that there will be a strong, positive correlation between social feedback and body image. A meta-analysis was conducted to determine the correlation between body image and eating disorders, yielding a moderately strong, positive correlation ( …

Quantification Of Neurite Degeneration Through Use Of An Optimized And Automated Method, Lauren Fuller

Honors Theses

Neurite degeneration is a cellular dysfunction commonly associated with neurodegenerative pathologies such as Alzheimer’s disease and Parkinson’s disease (PD). One common method of scoring neurite degeneration in micrographs involves calculation of a degeneration index (DI) using neurite fragment measurements obtained via the particle analyzer plugin of FIJI software. However, this method can be time consuming and subject to inaccuracies related to inadequate contrast. Here we describe a modified method for performing DI measurements with enhanced efficiency, accessibility, and accuracy compared to existing techniques. We developed a macro to automate the analysis process, enabling rapid and objective measurements of multiple images. …

Madame Bovary Syndrome: The Female Protagonist's Plight, Audrey C. Giesler

Honors Theses

The Madame Bovary Syndrome is a phenomenon that occurs among different female protagonists of the nineteenth century. Based on Gustave Flaubert’s novel Madame Bovary, this syndrome was defined by French philosopher Jules De Gaultier to describe chronic affective dissatisfaction with one’s life. The Madame Bovary Syndrome can be applied to the female protagonists in George Sand’s Indiana, Charlotte Perkins Gilman’s “The Yellow Wallpaper”, and Kate Chopin’s The Awakening. Each protagonist in these stories exemplifies chronic feelings of dissatisfaction, hopelessness, and despair due to the lack of control over their lives. With the rise of the middle class, women were now …

Treating The Trauma: Evaluating The Perceived Effectiveness Of Narrative Therapy On Individuals Who Have Experienced Trauma, Emily Faith

Honors Theses

Abstract

Narrative therapy (NT) has been utilized by many clinicians and found to be effective as an intervention with clients facing a wide range of issues. Focusing on one’s narrative has been given attention in many academic disciplines (e.g., social sciences, humanities and healthcare) and especially among popular written media and academic journals. Despite this attention and the various studies on its efficacy, there is a lack of research on client and non-client perceptions of this therapy. This ethnographic study’s purpose was to compare the perceived effectiveness of the NT between those who had previously participated in narrative therapy and …

Going In Circles: An Exploration Of Functions Into The Circle Group, Renee O. Richburg

Honors Theses

We investigate the properties of functions into the circle group. The circle group is given by the factor group R/Z. Functions into the circle group have real-valued domain and R/Z co-domain. Every real-valued function has an analogous function into the circle group. By wrapping the graph of a real-valued function around a horizontal cylinder with a circumference of one, we visualize the analogous function into the circle group. How does wrapping a real-valued function around such a cylinder affect the function outputs, limits, continuity, and rate of change? Function outputs are naturally transformed to reside on a circle with a …

Could The P75 Neurotrophin Receptor P75ntr Help Unlock The Mysteries Of Infertility?, Mayci Fullmer

Honors Theses

Histology is the study of microscopic tissue structures that examines the correlation between structure and function. This technique was utilized when analyzing the biological processes of folliculogenesis and oogenesis. These processes study the maturation of the ovarian follicle and production of an ovum, respectively. The p75 neurotrophin receptor (p75^NTR)has been identified to contribute to the maturation of ovarian follicles, but the role of p75^NTR in ovulation remains unknown. To investigate the role of p75^NTR in ovulation, an animal study analyzing the histology of the mouse ovary was conducted. In this study, the number of primary follicles, …

A Summary Of Current Research Into Neurodegenerative Disorders Using Drosophila Melanogaster, Chase Cortese

Honors Theses

Neurodegenerative disorders such as Alzheimer’s disease are characterized by damage to neural cells causing widespread neurological deficits. Historically, these diseases were deemed as inevitable declines in cognitive and neurological function that occurred with aging. Recent research has revealed, however, that these diseases have molecular bases allowing potential clinical intervention. The groundbreaking discoveries have been made using differing model organisms, which can replicate the phenotype and physiological cause of these disorders. One major model organism that has been used is the fruit fly, Drosophila melanogaster. They have served various roles in elucidating gene pathways and neurophysiological bases seen in these diseases. …

Classroom To Classroom: How Many Do You See? The Lack Of African American Teachers In K-12 Public Schools And How To Address This Issue Through Diverse Curriculum Development In Teacher Education Programs, Deonna Starks

Honors Theses

This study provides a descriptive study of DEI courses and admissions requirements among 4-year public universities and colleges. Using data and formation collected from Georgia State University, University of Georgia, Kennesaw State University, Fort Valley State University, the University of Tennessee at Knoxville, the University of Tennessee at Chattanooga, University of Memphis and Middle Tennessee State University, this thesis will examine the diversity, equity, and inclusion (DEI) courses offered at each individual university and propose a ClearPath and recommendations for further implementation of DEI curriculum and the retention and recruitment of preservice African American teachers. Previous research shows that the …

Utilizing Manganese And Rhenium Sediment Concentrations To Reconstruct Past Interglacial Southern Ocean Circulation Changes, Evan E. Rohde

Honors Theses

The circulation in the Southern Ocean is a component of global nutrient, heat, and carbon cycles. Changes in any of these cycles can dramatically change ocean conditions around the world. Therefore, any changes that occurred to this circulation in the past is of scientific interest. We hypothesize that changes in the glacial cycle of the planet can affect this circulation. Specifically, we hypothesize that the strength of circulation in the Southern Ocean can be reduced by conditions during interglacial, or warm climate, time periods. It is proposed that during the interglacial period of Marine Isotope Stage (MIS) 11 (425 to …

A Meta-Analysis Of The Human Uses Of Pteridophytic Species In Tennessee, Diana Sevier

Honors Theses

Pteridophytes are an ancient lineage of plants, composed of ferns and fern allies, which are spread across the globe. There is also a long record of humans using pteridophytes to their benefit, which includes the broad categories of medicine, ornamentation, food, phytoremediation, and agriculture. Understanding these concepts, the goal of this thesis was to conduct a meta-analysis which pulled together data from many resources on the 94 Tennessee pteridophyte species to create a repository of human use information, as well as to examine, analyze, and comment on the trends present within and between taxonomic groups of pteridophytes. The methods used …

Influence Of Reactant Stoichiometry On The Composition Of Nanojar Product Mixtures, Ali Al Maamuri

Honors Theses

Nanojars are large metal-organic complexes comprised of 26‒36 repeating units of [Cu(OH)(R-pz)] (R-pz = pyrazolate anion, where R is either H or a substituent), which strongly and selectively incarcerate highly hydrophilic anions. Nanojars are prepared by the reaction of a copper salt, pyrazole, a base and an anion source (which could be the copper salt itself or a different salt). Usually, a mixture of nanojars of different sizes is obtained: {anion[Cu(OH)(pz)]n} (n = 26‒36; anion = carbonate, sulfate, etc.). The value of n depends on the incarcerated anion and the substituents on the pyrazole moiety. It has become apparent that …

White Supremacy Culture And Capitalism As Co-Dependent Systems Of Oppression, Allegra Kistler Ellis

Honors Theses

This thesis seeks to discuss questions surrounding the intricacies and intertwining narratives of white supremacy culture and capitalism, and other systems of oppression that they fuel. For my research, I intentionally used anecdotes, essays, poems, books, and social media posts by primarily queer, trans, Black and Indigenous women and femmes. In doing so, I delve into the inherent relationship between whiteness, white exploitative institutions, and power. I discuss the history of the two systems of oppression in the United States through analyzing pillars and characteristics of white supremacy culture and capitalism, western colonized science and research, sexism, white feminism, fatphobia, …