Digital Commons Network^™

Development Of An Immunoblot To Detect Human Antibodies Against Sars-Cov-2 Virus Proteins, Shivum Desai

Honors Theses

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a virus that infects cells in the lungs, nasal passages, and intestines via the ACE2 receptors of the host, and leads to the coronavirus disease (COVID-19). Since the occurrence of the pandemic in December 2019, there have been 114 million cases worldwide in which 2.5 million lives have unfortunately been taken away.

Being diagnosed with a past infection stems questions among those that have tested positive through antibody testing. The problem here is that patients were notified that they have antibodies resulting from a SARS-CoV-2 infection, but in fact they may not …

Enamel Corrosion Levels On Squirrel Teeth From The Fox Canyon Locality, Pliocene Of Kansas, Emma Tennyson

Honors Theses

The enamel of teeth may be corroded after death, especially if the teeth pass through the digestive tract of a predator with low gastric pH. This study characterized enamel corrosion of fossil squirrel teeth from two species (Otospermophilus rexroadensis and Ictidomys meadensis) obtained from the Fox Canyon locality of Kansas. Using microscopic imaging, I categorized teeth based on corrosion level. Overall, 45% of specimens exhibited heavy to extreme corrosion. There were no significant differences in the distribution of corrosion categories between both upper and lower teeth of either species (O. rexroadensis: X2 (3, N = 140) = .562, p= .905; …

Comparisons Of Silver Nanoparticle Synthesis Methods By Microwave And Non-Microwave Using Hydrogen Gas As A Reducing Agent, Sofia Erech Hanapin

Honors Theses

Synthesis and characterization of silver nanoparticles are of current interest. This research project describes a simple and rapid synthesis of silver nanoparticles upon reduction of Silver (I) oxide (Ag2O) by molecular hydrogen (H2) at elevated temperature (70 – 100 °C) and a pressure of > 1 atmosphere by heating the aqueous mixture using a common kitchen microwave. This reaction generates naked silver colloids that contain no foreign stabilizers other than metal particles in aqueous media. Its application of an antibacterial effect was monitored by using biological cultures using the Kirby-Bauer Test.

Thermodynamic Analysis Of Pamam Dendrimer Synthesis, Ryutaro Einar Jacobson

Honors Theses

The objective of this research was to determine kinetic and thermodynamic data about the reaction between ethylene diamine and methyl acrylate which is used in the production of PAMAM dendrimers. Establishing a rate law and finding values such as rate constant, activation energy, and Arrhenius coefficient will help in determining the best possible conditions for the reaction. A rate law was established through the method of initial rates, comparing the rates of reactions with different initial concentrations to one another. Additional reactions were run with active cooling to observe the effects on rate and reaction progress, and finally reactions were …

A Note On Cannibalism And Synchrony In Seabird Egg-Laying Behavior, Yosia Nurhan

Honors Theses

During years of high sea surface temperature, food resources for glaucous-winged gulls (Larus glaucescens) are scarce. In response, male gulls cannibalize the eggs of neighbors. When this occurs, female gulls in dense areas of the colony adopt a tactic of egg-laying synchrony, in which they lay eggs synchronously on an every- other-day schedule. Field observations show that the first laid egg of each clutch is the most likely to be cannibalized. In this paper, we analyzed a discrete-time model of egg-laying behavior that tracks egg order in the nest. Using Jury Conditions, we found that the equilibrium destabilizes into a …

Finding Optimal Opa-Iblc Derivatized Amino Acid Analysis Parameters With Three-Dimensional Fluorometric Scans For Hplc Method Validation, Aaron Jacobs

Honors Theses

Three-dimensional fluorometric scans of OPA-IBLC derivatized glutamic acid and histidine solutions revealed that decreasing concentration maintained maximum λem but produced different maximum λex. In pH 0.4 M sodium borate buffer (pH 10.4), 50 μM derivatized amino acid solutions had maxima around 350- to 450-nm λex-λem where 12.5 μM solutions had maxima around 230- to 450-nm λex- λem. In the lower concentration, the λex peak at 230 nm was about 80% higher than 350 nm. Thus, collecting spectra with 230 nm λex would provide better LOD and LOQ. Results inform HPLC standard concentrations since differential quenching effects may produce non-linear calibration …

Evaluation Of Phonotactic Behavior In Male-Exposed Female Cricket Acheta Domesticus, Janelle An

Honors Theses

Phonotaxis is defined as the movement of organisms in response to an auditory stimulus. It plays an important role in helping animals find a potential mate, and thus it is worthwhile to understand what factors may influence phonotaxis. Phonotactic behavior in virgin female cricket Acheta domesticus has been the focus of multiple studies, which have reported a degree of variability among individuals. Several factors that have been reported to influence such variability include age, environmental temperature, and the presence of certain neuromodulators. This study investigated possible changes in the behavioral responses of young females when raised with males but not …

Comparison Of Enamel Microstructure Of Ictidomys Tridecemlineatus Formed During Hibernation Versus The Active Season, Amanda Cho

Honors Theses

Ground squirrel incisors grow continuously, preserving a record of their most recent weeks of life. Previous research demonstrated that an abnormality in the surface of incisor enamel and dentin of thirteen-lined ground squirrels (Ictidomys tridecemlineatus) corresponded with hibernation. Using scanning electron microscopy, we compared internal microstructure of incisor enamel deposited during and outside of hibernation to determine if surface disruptions corresponded to differences in internal microstructure. For one specimen, hibernation enamel displayed irregularities in microstructure that were not present in non-hibernation enamel, but this difference was not observed in other specimens. Given these inconclusive results, further research is warranted.

One Writer, Two Genres: Composing And Analyzing Creative Nonfiction And Fantasy, Kara Herrera

Honors Theses

Creative writers face a wide range of options when they sit down to craft art out of words. Available to them are many genres, each with their own characteristics or traits. Additionally, many writers have accomplished self-reflection in interviews, Q&A sessions, and in print. It is not unusual to find writers taking their craft and turning it into their subject matter. This project aims for the same. In order to analyze the similarities and differences in the writing process across genres, a “writing about writing” essay is included along with four creative nonfiction essays and a young adult fantasy novel …

Modulation Of Apoptosis In Breast Cancer Cells Mda-Mb-157, 93a And 93b By Aqueous Extract Of Chinese Medical Herb Scutellaria Barbata, Nathaly Manrique

Honors Theses

Scutellaria barbata (S. barbata), a Chinese herb used in Traditional Chinese Medicine has been known to contain anti-cancer properties. SB has been investigated as a potential treatment for multiple types of cancer including colon cancer, glioblastoma, and ovarian cancer. Breast cancer cell lines MDA-MB-157 and its APC-mutants 93A and 93B are more resistant to treatment due to genetic modifications. In this study, the effectiveness of S. barbata in apoptotic modulation of breast cancer cell lines MDA-MB-157, 93A, and 93B was investigated. Assessments were performed using green/red/blue fluorescent Apoptosis/Necrosis Detection Kit and the Human Apoptosis Antibody Array - Membrane (43 Targets) …

Brains Versus Brawn: Militarization And Women In Modern Policing, Emilee Shae Eversole

Honors Theses

This work explores the paramilitarism that has taken policing by storm over the last few decades, the adverse effects caused by it, and what women in policing do to counteract them. Previous research has shown that some individuals believe this type of militarization of policing has severed the relationship between law enforcement officials and their communities, and false beliefs regarding the ability of women to serve as police officers seem to run rampant. However, newer research suggests that women in policing provide a refreshing contrast to this paramilitarism through less invasive tactics, resulting in a more trusting relationship between officers …

It’S All About The Ferns: A Literature Review Of Species Concepts Referenced In New Pteridophyte Species Described Since 1989, Nicholas A. Koenig

Honors Theses

Taxonomy is the field of science responsible for giving names to all living organisms. These names are given based on the data available or discovered, and the foundational knowledge about related organisms. All fields of science are theory-laden with testable hypotheses made atop, and taxonomy is no exception. However, trends in descriptions of new species point towards an implicit citation of the underlying theories (species concepts) and hypotheses (proposed species) rather than explicit statements that are common for other fields of science. Therefore, to assess the status of pteridophyte taxonomy, we conducted a literature review of all new pteridophyte species …

Healing Hands: J. R. R. Tolkien’S Germanic Understanding Of Medicine And Monarchy, Elizabeth Lucas

Honors Theses

In The Lord of the Rings, J. R. R. Tolkien uses Aragorn’s healing abilities to solidify his identity as the rightful king. While it is made clear that this ability to heal is a sign of kingship, it is never clarified from where this belief arose. There is no other lore in The Lord of the Rings, The Appendices, or in The Silmarillion to suggest that healing hands were at all common among the kings of Númenor, Arnor, or Gondor, so the rhyme remembered by the old wife in the House of Healing may be surprising. Aragorn’s abilities, however, do …

Impact Of Antibiotic Alternatives On Concentrations Of Escherichia Coli Harbored By Broiler Chickens Challenged With Coccidiosis, Emma King

Honors Theses

No abstract provided.

The Modulation Of Interleukin-4-Induced Immune Responses By Prostaglandin D2 And Its Glyceryl Ester, Hannah Scheaffer

Honors Theses

No abstract provided.

Bio-Printed, Bio-Functionalized Plga-Kgn Scaffolds As An Augmentation To Microfracture, James D. Warren

Honors Theses

Microfracture is a commonly performed surgical procedure that aims to regenerate damaged cartilage in patients with focal cartilage lesions. Though fairly successful, microfracture is limited by the produced fibrocartilage, which is mechanically inferior and less durable than normal hyaline cartilage. The proposed augmentation to microfracture aims to improve its clinical outcomes by introducing a bio-printed poly(lactic-co-glycolic acid) (PLGA) scaffold functionalized with kartogenin (KGN), a small bioactive molecule known to induce mesenchymal stem cell differentiation into hyaline cartilage. The scaffold’s release characteristics were evaluated over 40 days by HPLC, which confirmed sustained release of KGN from the scaffold. Tensile testing results …

Neurodiversity And Online Communities: Why They Matter, Laura Ingouf

Honors Theses

Neurodiversity is an approach that accepts and embraces neurological differences as a natural variation, and neurodivergent people are those whose brains work differently from what is considered the norm by society. This thesis examines the impact of online neurodivergent communities on the neurodivergent people that participate in them through the use of a qualitative online survey distributed via Twitter and Mastodon, a decentralized Twitter alternative. It is informed by the researcher’s experience as a neurodivergent person in these online communities and analyzes the functions that these online communities serve for the neurodivergent people who participate in them and how this …

Potential Of Biochar For The Removal Of Waterborne Microbial Contaminants, Shankia Musser

Honors Theses

A Guadua chacoensis bamboo biochar, which has shown efficacy for heavy metal, organic and inorganic compound remediation, was tested for its capacity to remove Escherichia coli, heterotrophic bacteria, and total coliform bacteria to determine if the biochar is a viable option for removal of pathogenic microbes in drinking water applications. Two distinct approaches were used to perform this assessment. In the first approach, an axenic culture of E. coli was treated using varying amounts of biochar and E. coli survival was assessed. In the second approach, environmental water samples taken from surface water at the Mississippi State University campus were …

Cultivation Effects From Television Crime Dramas To Forensic Practices, Stephanie P. Mobley

Honors Theses

Television and its effects have been frequently studied due to the prevalence of television in today’s society. Cultivation theory examines these effects by claiming that people’s perceptions of the real world are shaped by the social reality portrayed on television. This paper used this theory to examine a link between college student’s viewership of television crime dramas and their opinions about forensic practices. It used quantitative survey questions and previous research to come to conclusions for the research questions. The three research questions asked whether frequent viewing of crime dramas cultivated false beliefs about three forensic practices, (fingerprint analysis, polygraph …

The Influence Of The Gut Microbiota And Alzheimer’S Disease, Mackenzie E. Gibbs

Honors Theses

Alzheimer’s disease is a neurodegenerative disease that effects the neurons in the brain and can lead to cognitive impairment and death. The main aspects of Alzheimer’s research focus on genetic factors contributing to the disease, but the microbiota gut-brain-axis may be playing a potential role in Alzheimer’s development. The human body has an abundant microbiota to help our bodies carry out daily needs, but the amount of microbiota present has to be kept in a tolerance range by the immune system. If there is an increase in the amount of gut microbiota present in the human body, inflammation can occur …

Warming Stimulates Sporulation Rates And Alters Community Structure Of Litter-Associated Fungi In Streamside Channel Experiment, Kaitlin D. Beasley-Polko

Honors Theses

Fungi, such as aquatic hyphomycetes, are important decomposers of plant litter in temperate forested headwater streams providing energy and nutrients for the higher trophic levels in these ecosystems. According to current climate change predictions, stream water temperatures are expected to rise significantly in the near future. This project addressed the effects of temperature on sporulation rates and community structure of aquatic hyphomycetes on substrates of different carbon quality (maple and rhododendron leaf litter and wood veneers). The experiment was conducted in streamside channels fed with stream water (ambient, +2°C and +4°C) and set up to mimic small streams. We found …

Shark Diversity And Relative Abundance At Myrtle Beach, Sc Fishing Piers, Lynsey E. Isner

Honors Theses

Sharks are frequently observed at fishing piers (Barwick et al. 2004; Martin et al. 2019). These piers offer structural habitats for shark prey items, such as smaller fish and invertebrates, which can attract sharks to piers (Barwick et al. 2004; Heupel 2005). Additionally, fishers often clean their catch and discard entrails at the pier, which also may attract sharks (Martin et al. 2019). Moreover, other factors could play a role in attracting sharks to piers. These include water quality parameters, like salinity and temperature, and the physical characteristics of the pier (Ulrich et al. 2007; Castro 1996; Heupel 2005).

Effects Of Caffeine Consumption On Cognitive Performance In Anatomy And Physiology Students, Sydney Wingfield

Honors Theses

Caffeine has often been associated with college students and their study habits; however, little research has been done to explore if it is actually beneficial to the students’ cognitive performance and academic success. While current studies have explored various aspects of caffeine’s influence on specific areas of cognition relevant to their own studies, there is a lack of research on how it influences academic settings. Within the present study, it is believed that caffeine usage will not cause a significant improvement in individual academic performance despite of the known physiological and cognitive effects on the students. The study consisted of …

Indolizine Donor-Based Dyes For Applications In Fluorescence Biological Imaging, William Meador

Honors Theses

NIR emissive fluorophores are intensely researched due to their potential to replace modern imaging procedures. Many molecular strategies have been employed in the literature to optimize fluorophores for deeper NIR absorption and emission, biocompatibility, and higher fluorescence quantum yields. Amongst the fluorophores studied to date, proaromatic indolizine donors are attractive alternatives to traditional alkyl amine and indoline based donors due to their 1) lower energy absorption and emission facilitated by proaromaticity, 2) large Stokes shifts due to increased dihedral angles about the π-system, 3) ease of functionalization and capacity for bioconjugation at the phenyl ring, and 4) potential for further …

Genetic Diversity & Connectivity Of Chasmanthium Latifolium (Poaceae) In Pennsylvania & The Effect On Conservation Status Of A Rare Species, Jonathan D. Hayes

Honors Theses

Chasmanthium latifolium (Michx.) Yates (Poaceae) is a loosely colonial, rhizomatous, perennial grass species that lives in riparian habitats, making it fittingly referred to as river oats. Native to the southern Midwest and the eastern half of the United States, C. latifolium reaches the northeastern edge of its range in Pennsylvania. Within Pennsylvania, eleven extant C. latifolium populations are found along four waterways: the Monongahela River, the Susquehanna River, and two tributaries to the Susquehanna River. This limited state distribution exhibits an east-west disjunct distribution, where western populations are largely separated from eastern populations with one centrally located population. Between the …

The Transcendental Foundation Of Kant's Cosmopolitanism, Daniel J. Ellison

Honors Theses

Scholarship on Kant’s philosophy of history has insufficiently considered its place in the larger system of transcendental idealism. In this project, I argue that Kant’s guarantee of progress in history is grounded in his universal characterizations of human nature, which he makes both explicitly, as with the notion of “unsociable sociability” put forth in “Idea for a Universal History from a Cosmopolitan Perspective,” and implicitly, as with what I term a responsiveness to reasons. These characterizations are grounded, I claim, in an attribution of reason which is always already achieved to the constitution of human beings, which emerges out of …

Gold Mining Districts And Path Dependence, Jason T. Dunn

Honors Theses

This paper applies quantitative spatial analysis to the long-term impact of Western gold rushes, studying the effect of 19th century US mineral districts on modern (2010) population density, as a proxy for long-term economic growth. OLS regression estimates show positive effects for areas adjacent to historic mining districts. Census tracts within 15 miles of a mineral district but not containing one are 29.8% more dense than other tracts. Additionally, capital-intensive/large-scale mining was more persistent than labor-intensive/small-scale methods, and path dependence is achieved mainly through agglomeration. This research corroborates historical arguments focusing on the development of Western infrastructure for long term …

A Generalized Polar-Coordinate Integration Formula, Oscillatory Integral Techniques, And Applications To Convolution Powers Of Complex-Valued Functions On $\Mathbb{Z}^D$, Huan Q. Bui

Honors Theses

In this thesis, we consider a class of function on $\mathbb{R}^d$, called positive homogeneous functions, which interact well with certain continuous one-parameter groups of (generally anisotropic) dilations. Generalizing the Euclidean norm, positive homogeneous functions appear naturally in the study of convolution powers of complex-valued functions on $\mathbb{Z}^d$. As the spherical measure is a Radon measure on the unit sphere which is invariant under the symmetry group of the Euclidean norm, to each positive homogeneous function $P$, we construct a Radon measure $\sigma_P$ on $S=\{\eta \in \mathbb{R}^d:P(\eta)=1\}$ which is invariant under the symmetry group of $P$. With this measure, we prove …

The Quantitative Assessment Of Pond Scum: An Examination Of The Biogeochemistry Of Phosphorus Cycling In The Belgrade Lakes, Abbey M. Sykes

Honors Theses

The internal recycling phosphorus in freshwater lake bottom sediments represents a significant source of hypolimnetic phosphorus (P) release for many of Maine’s lakes. In summer months, Maine lakes often thermally stratify and the lake hypolimnion develops anoxia, leading to a reduction in redox potential at the sediment-water interface. These reducing conditions facilitate the reductive dissolution of ferric iron, and, since phosphorus is often present in freshwater lake sediments as solid FeOOH-PO₄ complexes, results in release of soluble phosphorus into the water column. Our current study presents field and laboratory data from sediment fractionation extractions designed to quantify concentrations of …

Impact Of The North American Monsoon On Molt Migrant Passerines, Liuqingqing Yang

Honors Theses

Breeding, molt, and migration place considerable yearly demands on migrating passerines in North America. Due to conflicts in energy allocation, many species have evolved migration strategies that prevent temporal overlap in these processes. However, there is recent evidence that some passerines which breed in western North America migrate to intermediate stopover sites to carry out molt, conflating molt and migration. Factors influencing the evolution of such a strategy are believed to include both aridity on breeding grounds and dependable flushes of late-summer productivity in the southwestern United States and northwestern Mexico. This productivity occurs due to the brisk rainfall of …