Digital Commons Network^™

The Correlation Between The Microbiome And Neurodegenerative Disorders Such As Alzheimer Disease, Aurora Mokris

Honors Theses

Recent studies suggest that there are 1.3 times as many microbial cells as human cells in the body (Abbot, 2016). Another study claims that the combined genomes of this microbiota is 150 times that of the human genome (Zhuang & Shen, 2018). If you have ever had the feeling that you are not alone in an empty room you are most certainly correct. Your body is teeming with millions of organisms living in mutualistic symbiosis with you and surrounding microbes, but at times, this seemingly harmonious relationship can be disturbed, resulting in serious physical and psychological changes to the human …

Deaf And Hard Of Hearing Accessibility At Drive-Through Restaurants, Regina Mcleod

Honors Theses

People who are deaf or hard of hearing deserve fair and accessible accommodations, which include drive-through restaurants. It is not a fair solution to force this population to go inside an establishment to order, especially due to the fact that many restaurants close the inside of their restaurants at night but will leave their drive-throughs open. According to legal cases and surveys conducted, accessibility at drive-through restaurants is a prodigious issue for members of the deaf and hard of hearing communities in the United States. Based upon these findings, there is a major lack of accessibility, in addition to discrimination, …

Exploring A Child’S History For Optimal Treatment Of Food Selectivity., Briana Lear

Honors Theses

Food selectivity is defined as “food refusal based on type, texture, temperature, or appearance of food, leading to a self-restricted diet” (Suarez, 2015). Food selectivity affects children of all ages. Food selectivity refers to when a child is eating as few as 5-10 different foods and demonstrates food refusal behaviors, which can make mealtime a challenge for children and their families (Suarez, 2015). Occupational therapy addresses activities of daily living (ADLS), therefore feeding, including food selectivity is included within the OT scope of practice. There is a need to create a comprehensive and thorough document to collect a client’s history …

Effects Of Age And Exercise On Density Of Sympathetic Innervation And Localization With Nerve Growth Factor And Glial Cell Line-Derived Neurotrophic Factor In Vascular Tissue, Kori Mecklenburg

Honors Theses

Hypertension is a condition that affects nearly 75 million people in the United States (Merai et al, 2017). To better understand this mostly idiopathic condition, the role of survival factors on arterial innervation must be understood. Nerve growth factor (NGF) and glial cell-line derived neurotrophic factor (GDNF) have been shown to support development and maintenance of the sympathetic nervous system. The aim of this study was to reveal how density of sympathetic innervation changes in mesenteric arteries over time and with six-months of exercise. Additionally, this study aimed to reveal the localization of GDNF and NGF alongside these changes in …

Breaking Down Barriers To Sustainable Eating At The University Of Dayton, Lauren Murray

Honors Theses

Sustainability is at the forefront in many conversations and innovations at the University of Dayton (UD), ranging from the Hanley Sustainability Institute to the Sustainability club. However, sustainability extends beyond water and energy conservation. In addition to these, students and faculty at UD can impact their carbon footprint through sustainable eating. The purpose of this research was to define sustainable eating, determine the carbon footprint of foods served in the UD dining halls, and develop and evaluate an educational intervention aimed at UD students within the Virginia West Kettering dining hall. The results of this research were considered in the …

Stage Based Matrix Modeling Of Trifolium Stoloniferum Restoration Populations At Taylor Fork Ecological Area, Madison County, Kentucky, Theodore J. Brancheau

Honors Theses

Trifolium stoloniferum is a federally endangered plant species that was once abundant from parts of the eastern United States like West Virginia and Kentucky and into parts of the west, such as Kansas, but was considered extinct for many years before the species was rediscovered. Although the species is recovering overall and is pending to be downlisted to threatened, this species, and many others, can benefit from more detailed population viability analyses such as the one conducted for the project. The objective of this research was to conduct a stage-based population viability analysis of restoration populations five and seven, located …

Propionate Enhances The Antimicrobial Defenses In Macrophages Against Listeria Monocytogenes, John Weis

Honors Theses

Propionate is a short chain fatty acid produced by the bacteria in the human gut. It has a wide range of nutritional functions in the human body. Several studies have also reported the effects of propionate on immune cell activation. In this study, we used Listeria monocytogenes as a model pathogen to determine how and what the effects of propionate on immune cells influence cell susceptibility to infections. Listeria is a dangerous intracellular pathogen that can replicate inside immune cells such as macrophages. Therefore, we can assess the impact of propionate on infection susceptibility by performing cell culture infections. We …

Modulation Of Listeria Monocytogenes Carbon Metabolism By Short Chain Fatty Acids, Diksha Bedi

Honors Theses

Listeria monocytogenes, a bacterial pathogen, is associated with foodborne infections in humans. Listeria encounters short chain fatty acids (SCFAs) during its transit through the intestine but its metabolic responses to SCFAs are not fully understood. To determine how Listeria metabolism is affected by SCFAs, I performed basic microbiology assays, including monitoring optical density, determining acetoin production, and measuring culture pH levels. I also performed preliminary 13C-NMR assays to provide a more in-depth look into carbon metabolism in SCFA-treated Listeria. I found that propionate-supplemented Listeria produced significantly more acetoin compared to no supplemented controls. Because acetoin is a product of central …

In The Face Of Antimicrobialsfactors Contributing To Listeria Monocytogenes Survival And Development Of Resistance, Andrea M. Vietti

Honors Theses

Bacterial antibiotic resistance is on an alarming rise worldwide, thus posing an urgent threat to human health. The rise in antibiotic resistance can be attributed to the overuse and misuse of antibiotics in both the healthcare and agricultural industries. In order to address this concern, this research aimed to identify environmental conditions that may lead to the development of antibiotic resistance in Listeria monocytogenes. L. monocytogenes is a foodborne pathogen capable of causing the disease listeriosis and is especially dangerous for immunocompromised populations. Although infected individuals are treated with antibiotics, an alarmingly high mortality rate of 20 percent still persists; …

An Analysis Of The Developmental Enrichment Of The Seattle Children's Playgarden, Caitlin Koob

Honors Theses

This paper analyzes the opportunities for developmental enrichment, as provided by the Seattle Children’s PlayGarden, from the perspective of occupational therapy. The PlayGarden, located in Seattle, Washington, is an inclusive playground, preschool, and summer camp that promotes inclusion of children with disabilities. The analysis highlights each area of occupation, as identified in the Occupational Therapy Practice Framework, and discusses the garden’s contribution to facilitate growth in those specific skills (American Occupational Therapy Association [AOTA], 2014). The intentionality of the design and program structure advocates for children to maximize their independence in activities of daily living, despite the play-based approach. …

Addressing Local Food Inequity: A Youth Participatory Action Research Project In The Alternative High School In Waterville, Maine, Aanavi Patodia

Honors Theses

Food security is a global issue. As food insecurity increases, it is continually important to find solutions. Food insecurity in the United States in children is visible is partially addressed via school programs, like the National School Lunch Program (NSLP) and School Breakfast Program (SBP). This project explores food inequity in the Alternative High School in Waterville, Maine, which participates in the NSLP and SBP to reduce food insecurity. This project used a Youth Participatory Action Research (YPAR) process to explore school meals and, to a larger extent, food equity from the Alternative High School students’ perspectives as co-researchers. Through …

African Savannah Elephant Group Size And Behavior In The Makgadikgadi Pans National Park, Botswana, Katherine S. King

Honors Theses

African savannah elephants (Loxodonta africana), the largest elephant species, influence the structure of the environment they inhabit. Elephants exhibit complex patterns of social behavior between individuals within a population. Many behavioral studies focus on interactions among individuals within a population rather than broader trends related to group size. My study seeks to understand how male African savannah elephant group size is influenced by seasonality, age, physical condition and distance to permanent water resources. I examined the interaction of these variables in two ways: (1) a literature review of elephant behavior and conservation, and (2) an analysis of male …

Developing A Predictive And Dynamic Moose-Vehicle Collisions Model In Maine, Yue Yu

Honors Theses

Wildlife-vehicle collisions are a major form of human-wildlife conflict. Predictive animal-vehicle collision models have been developed to identify collision hotspots in Maine and guide mitigation strategies. However, most current models are static and unable to produce dynamic forecasts that incorporate changing climate and weather. The goal of my study was to develop a predictive and dynamic model of animal-vehicle collisions in Maine, USA. More than 6,700 moose-vehicle collisions (MVC) occurred from 2003 to 2017 in Maine, raising road safety, socio-economic, and wildlife conservation concerns. I sought to identify factors that contribute to a higher probability of MVCs by comparing two …

Preliminary Study On The Effects Of Akkermensia Muciniphilia On Akt Phosphorylation In Diabetic Pig Models, Brian Ko

Honors Theses

The onset of type 2 diabetes has been shown to affect the Akt signaling pathway, responsible for modulating cellular metabolism. The pro biotic Akkermensia muciniphilia has been recently shown to have an anti-inflammatory, anti-diabetic effect on animals inoculated with it, particularly within the Akt signaling pathway. This preliminary study utilized a twofactor experimental design with streptozotocin-induced diabetes and the presence of Akkermensia muciniphila in pig models in order to elucidate the probiotic's mechanism of action on the disease. Following analysis of insulin-sensitive tissues of muscle, pancreas, and liver, there was observed a mixed response to the presence of the probiotic …

Revealing The Role Of Short Chain And Polyunsaturated Fatty Acids As Regulators Of Metabolic Activity And Gene Expression In Ovarian Cancer, Abigayle Ochs

Honors Theses

Abstract

Previous research using the chicken model has provided evidence that a flaxseed-supplemented diet decreases both the severity and the incidence of ovarian cancer. Flaxseed is a source of omega-3 (OM3) polyunsaturated fatty acids (PUFA), particularly α-linolenic acid (ALA). ALA is converted into longer chain OM3s, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which inhibit prostaglandins, thereby inhibiting oxidative stress, inflammation, angiogenesis, and proliferation. The dietary fiber component of flaxseed can be fermented in the gut to produce short chain fatty acids (SCFA). Butyric acid, a commonly studied SCFA, has been shown be an important metabolic regulator by acting as …

“Il Est Bon, Aujourd'hui, Le Boudin” : La Nourriture Esthétique Et Le Goût Dans Le Roman Naturaliste Zolien, Elena Palazzolo

Honors Theses

La lecture de n’importe quel texte dans les Rougon-Macquart rend clair que leur romancier, Emile Zola, était intéressé sinon obsédé par le symbolisme et les motifs alimentaires. La série, écrite entre 1871 et 1893, couvre la vie d’une famille sous le Second Empire et représente les grands problèmes sociaux du jour notamment les inégalités entre la bourgeoisie et la classe ouvrière en illustrant le chômage, l’alcoolisme, la faim chronique et les lieux de travail dangereux. D’un côté, la discussion de la nourriture à l’intérieur de ce discours semble évidemment pratique ou idéologique. Dans les mots de Albert Sonnenfeld, « Zola …

Deferred Action For Childhood Arrivals: A Comparative Analysis Of Access To Education And Healthcare For Immigrants Before Daca, Under Daca, And Under The Dream Act, Levi C. Bevis

Honors Theses

The United States has long been considered a nation of immigrants, welcoming individuals and families of every background to build a better future for themselves and the country. Throughout various periods of its history, however, the U.S. has fluctuated between welcoming and exceptionally restrictive immigration policies, with changes are often generating passionate debate from all ideological standpoints. A significant development in the modern U.S. immigration system is the implementation of the Deferred Action for Childhood Arrivals (DACA) program under the Obama Administration. This program allowed certain young undocumented immigrants who met established criteria to qualify for deportation protections. With approximately …

Nutritional Content Of Mississippi Child Care Centers Participating In The Child And Adult Care Food Program: 1995 To 2019, Katelyn Marie Inserra

Honors Theses

Childhood obesity rates are increasing in the United States and the condition is more prevalent in the Southeast than in other areas of the country. Children who are obese or overweight during childhood have a much higher chance of remaining overweight throughout their lives, and the best way to combat child obesity is through influencing young children’s nutrition patterns. Many children spend a significant amount of time in childcare outside of their home, which may be responsible for providing adequate nutrition for at least two meals per day. This study evaluated the menus of Mississippi childcare centers participating in the …

Staff Perceptions Of Healthy Eating Opportunities And Choices On A Southern University Campus, Rebecca Gwendolyn Miller

Honors Theses

Maintaining a healthy workforce can help an employer to save money in the long run, due to factors such as fewer health-related absences and higher employee productivity. Obesity, a disease with many factors, is accompanied by many comorbidities. Food and beverage choices can play a strong role in the development of obesity. The purpose of this study was to explore factors that influence staff eating behavior in a large university in the Southeastern United States, using a qualitative research design. Additionally, staff members provided possible solutions to improve the eating environment on the University’s main campus. Using a structured question …

Food Waste In German Households: A Policy Analysis, Carlie Maree Vowell

Honors Theses

This thesis examines the issue of food waste in Germany and proposes policy solutions for food waste in German households. The author analyzes the history and background of sustainability and food waste in Germany in order to recommend a change in policy. The author uses a systematic literature review as the primary method for investigating food waste in Germany. The findings indicate that household food waste occurs due to a lack of planning, misreading food labels, misconceptions about food, improper food storage techniques, and a lack of awareness on the economic and environmental implications of food waste. Moreover, various demographic …

To Sleep Or Not To Sleep, That Is The Question: Sleep, Anxiety And Depressive Symptoms In Pregnancy, Alexis B. Miller

Honors Theses

Pregnancy is a time associated with many changes in a woman’s body including hormonal, metabolic, physical, and physiological changes (Miller, 2004; Okun, Kiewra, Luther, Wisniewski, & Wisner, 2011). A related concern is pregnant women and the impact of disturbed sleep. According to the Centers for Disease Control and Prevention (CDC), over 36% of the population in Mississippi experience an insufficient amount of sleep (CDC, 2014). Moreover, sleep disturbances in pregnancy are significantly associated with antenatal depressive and anxiety symptoms (Volkovich, Tikotzky, & Manber, 2015; Yu et al., 2017). The present study assessed potential relations between sleep disturbances, anxiety, depressive symptoms …

Evaluation Of School Wellness Policies Implementation As Measured By The Organizational Readiness To Change Theory, Elizabeth B. Quirk

Honors Theses

BACKGROUND: Overweight and obesity trends have been increasing drastically for the past twenty years. School wellness policies have been put into place to help decrease overweight and obesity prevalence. Analyzing a school’s organizational readiness to change for full implementation of wellness policies could identify areas that are contributing or hindering successful implementation of federal regulation of policies and policy outcomes. METHODS: This pilot study included 21 participants, all of whom served as a school wellness coordinator, either at the district or school level in Mississippi. Each participant completed a six-part questionnaire addressing school wellness policy implementation. Survey item development was …

A New Consultation Service For Community Pharmacies? An Investigation Of Pharmacists' Perspective On Implementing A Weight Management Program, Shelby N. Strength

Honors Theses

Pharmacists are capable and interested in providing a targeted weight management intervention addressing the high rates, and associated risk, of obesity. A series of in-depth phone interviews with Mississippi community pharmacists were used to gain their perspective on a systematic approach for delivering a weight and obesity management service to patients. Using qualitative content analysis, three themes were identified and analyzed. These themes included: pharmacist’s perceptions of patient’s needs, program structural components, and pharmacist’s implementational needs. These findings can be used to expand the role of pharmacists, serve as a model for the development of other consultation services, improve health …

Effects Of Vertical Transmission Of Maternal Antibodies To Mycoplasma Gallisepticum On Growth And Condition Of Eastern Bluebird Nestlings (Sialia Sialis), Mckenzie Xiang Denton

Honors Theses

Mothers display maternal effects to influence the development and success of offspring through processes such as resource allocation. In birds, this occurs largely through the egg yolk with the vertical transmission of antibodies to offspring to protect the vulnerable young from disease. Specifically, poultry and eastern bluebirds across the eastern United States are commonly infected by the bacteria Mycoplasma gallisepticum (MG), for which mothers may produce antibodies against. To test for the vertical transmission of MG-specific antibodies from mothers to nestlings in eastern bluebirds and the associated fitness effects, bluebird boxes were set up and monitored during the field season. …

State And Regional Comparisons Of Breastfeeding Policies And Rates: A National Study, Erin Johnson

Honors Theses

State legislation focused on promoting and supporting breastfeeding is relatively new, beginning in the 1990s. The purpose of this study is to determine if there is an association between state breastfeeding rates and state breastfeeding legislation and other institutional policies. The Centers for Disease Control and Prevention releases breastfeeding report cards with the most up-to-date state breastfeeding rates. These reports are used to examine the relationship between state breastfeeding rates and number of breastfeeding policies passed by a state. Government initiatives, such as Healthy People Initiative, and organizational practices, such as Baby-Friendly USA Inc., are also studied to determine their …

Fungal-Algal Speed Dating: Exploring Symbiotic Potential Of Fungal-Algal Cocultures, Natalie S. Williams

Honors Theses

Symbiotic relationships are widely studied phenomena in the biological world. Of particular interest are the ubiquitous relationships that exist between fungi and photoautotrophs. While much is known about the commonly occurring interactions that persist between fungi and a wide range of terrestrial plants, we are interested in exploring the symbiotic capacity between fungi and earlier diverging lineages of the plant kingdom, notably green algae. We developed an experiment to allow for a medium-throughput analysis of fungal-algal interactions using three model green algae: Chlamydomonas reinhardtii, Chlorella vulgaris, and Penium margaritaceum. With numerous replicated assays, these algae were individually paired with a …

Geographical Variability In Antibacterial Chemical Defenses Of The Caribbean Sponge Xestospongia Muta, Coleman Sisson

Honors Theses

Coral reefs are important and diverse marine ecosystems, and sponges represent the majority of species in Caribbean reefs. Xestospongia muta is a giant barrel sponge that is one of the most abundant and visible sponges on Caribbean reefs, and has been the subject of many studies. Xestospongia muta produces a diversity of secondary metabolites that have various ecological functions including allelopathy, anti-fouling, predation deterrence, and antibacterial activity. The chemical defenses produced by a sponge can change in response to various biotic and abiotic stressors, including water temperature, sedimentation, nutrient runoff, and predation. This study compared the antibacterial activity of X. …

Influence Of Multidisciplinary Educational Experiences On Engineering And Nutrition Student Perceptions On Collaboration And Soft Skill Development, Caroline Kay Crosby

Honors Theses

Solutions to most real-world challenges require collaborative efforts by multidisciplinary teams to provide the breadth of perspective and expertise needed to create effective solutions. Interprofessional education is a pedagogical practice used to provide students with opportunities to broaden their professional perspective by encouraging students to work as a part of a diverse team to solve complex problems. This process strengthens discipline-specific skill development, problem-solving skills, and appreciation for other disciplines while providing experiences that are attractive to potential employers. Many students are interested in food science, but no food science courses are offered at the university where this study took …

A Marketing Campaign For Hunters’ Home: A Home Of Hope Through Integrated Marketing Communications: Secondary And Primary Research Studying The Target Audience, The Hunting And Conservation Community, To Create An Imc Campaign Focused On Fundraising And Awareness, Josie Corinna Slaughter

Honors Theses

Through research and evaluation of current and experimental nonprofit marketing methodologies and practices designed to raise awareness and attract donors, this project’s purpose is to define and create a marketing campaign for a children’s home, named Hunters’ Home: A Home of Hope, in Namibia. Adopted and unique strategies will be identified to target the audience of hunters to help meet the specific needs of the home, which was founded by Marina Lamprecht, a person widely known and respected by participants in hunting and conservation. To create the marketing campaign, secondary and primary research was conducted. Secondary research was done through …

When Words Are Not Enough: The Development Of Human Trafficking In Venezuela Under The Maduro Administration, Holly Prather

Honors Theses

This thesis discusses the role the Maduro administration has played in the development of human trafficking in Venezuela. It does so by employing a qualitative analysis of primary sources such as governmental and NGO reports to determine the links between the Maduro administration and the increase of human trafficking. I argue that the Maduro administration has chosen to employ social policy, the Misiones (Misiones), as the state’s approach to human trafficking instead of enforcing anti-trafficking laws. This, in conjunction with unsound economic policy in response to the 2014 decline in oil prices, gives the Maduro administration a substantial role in …