Digital Commons Network^™

The Effects Of Low Dam Removal And Kayak Run Installation On The Biodiversity Of Fish And Macroinvertebrates In The Great Miami River In Downtown Dayton, Ohio, Sarah Anne Stalder

Honors Theses

Five Rivers Metroparks and the Miami Conservancy District have made plans to remove the upper portion of the Monument Avenue low-head dam in downtown Dayton due to the hazard it poses for recreation on the river and its negative impact on water quality and biodiversity. The plans also include modifying the dam with “kayak drops” and the construction of a second kayak drop slightly upstream of the location of the current low dam to enhance recreational opportunities on the river. Typically, low dam removal alter the flow and depth of a river, especially above the dam in the impounded area …

Nonlinear Analysis Of Balance Data In The Easter Seals Adult Day Services Population, Taylor Marie Schemmel

Honors Theses

81.1 million adults are expected to be affected by dementia in 2040. Individuals with dementia are twice as likely to fall as healthy individuals and three times as likely to sustain an injury during a fall. Unfortunately, current fall prevention techniques in place for cognitively healthy older adults are not as effective for those with dementia. The objective of this study was to examine balance differences between individuals of varying cognitive ability utilizing Easter Seals Adult Day Services. All study participants completed the Montreal Cognitive Assessment (MoCA). Clinical assessments were done in conjunction with static posturography data collection on a …

The Effect Of Early Life Social Stress On Anxiety-Like Behaviors And Ethanol Drinking In Female Long-Evans Rats, Alyssa Roeckner

Honors Theses

Among women with Alcohol Use Disorders (AUDs), women have higher rates of anxiety-disorders and are more influenced by early life stress compared to men. Preclinical models have been used to study the relationships between early life stress, anxiety-like behavior, and alcohol intake and preference. However, fewer studies have been done with female rats than male rats. To that end, chronic social instability was utilized as a model of early life stress in females. In this model Long Evans rats are placed in different pairs every day, and this has previously produced anxiety-like behavior in female rats (McCormick et al., 2008). …

Phosphorus Adsorption Through Engineered Biochars Produced From Local Waste Products, Peter Ogonek

Honors Theses

Phosphorus contained in agricultural runoff is a major anthropogenic contributor to harmful algal blooms (HABs). Biochars are carbon-based materials produced from the pyrolysis of waste biomass that have the potential to amend soils and remediate inorganic and organic contaminants from water. Engineered biochars tailored to adsorb phosphorus from water could reduce the availability of the nutrient in agricultural runoff, reducing the size and frequency of HABs. This study observed the phosphorus adsorption properties of engineered biochars produced from two source materials, oak sawdust and cornstalk residue, and being unmodified, acid-rinsed, or loaded with magnesium prior to pyrolysis, creating acid-rinsed, unmodified, …

Too Close For Comfort: The Effects Of Threatening Stereotypes On Perceptions Of Proximity, Anissa J. Maffett

Honors Theses

Do stereotypes influence how we perceive physical stimuli in our social world? The current project addresses this question by examining whether people differentially perceive targets based on whether a stereotype-based threat accompanies the target. Previous research finds that people evaluate physically threatening stimuli (e.g., spiders, aggressive people) as closer than non-threatening stimuli (Cole Balceitis, & Dunning, 2012). However, less is known about the role of stereotypes in activating a threat response. It was predicted that participants who are made aware of the threatening status of a group will perceive a member of that group as standing physically closer. Overall, the …

The Effects Of Omega-3 Fatty Acids On Intracellular Inositol Levels In Saccharomyces Cerevisiae, Jee Yeon (Joanne) Lee

Honors Theses

Bipolar disorder is a severe and chronic debilitating mental disorder characterized by extreme mood swings between mania and depression. The current medications for bipolar disorder, lithium and valproate, have been associated with numerous negative side effects. Although the therapeutic mechanism by which lithium and valproate (VPA) exert their effect is unknown, a leading hypothesis implicates inositol depletion as a mechanism of action. On the other hand, omega-3-fatty acids have been shown to relieve symptoms of bipolar disorder. In this study, we compare the effects of VPA to the effects of decosahexaenoic acid (DHA) on Saccharomyces cerevisiae growth and intracellular inositol …

Analysis Of Mammalian Carboxypeptidase O Expression Patterns, Christian Bardan

Honors Theses

Carboxypeptidase 0 (CPO) is a protease that cuts acidic amino acids from the carboxy termini of substrate proteins. This study aims to describe the expression patterns of CPO in small mammals. We have sampled tissue from four different species: thirteen-lined ground squirrel, eastern chipmunk, eastern mole, and northern short-tailed shrew. Samples were analyzed via Western blot using two CPO antibodies. Immunoreactive bands likely to be CPO, with molecular weights approximately 42 kDa, were seen predominantly in kidney, liver, and intestinal tissue samples. This suggests CPO could play a specific physiological function in these organs.

Synthesis, Isolation, And Characterization Of Potentially Carcinogenic Arginine-Based Heterocyclic Amines, Zachary Reichert

Honors Theses

Previous research demonstrates that meat cooked at high temperatures produces heterocyclic amines (HCAs)—a class of carcinogenic molecules—from burned creatin(in)e and amino acids. However, research performed in our lab, as well as in the peer-reviewed literature, suggests that substituting arginine for creatin(in)e may lead to HCA formation. Arginine is structurally similar to creatin(in)e and can be found abundantly in soy-based food products. Therefore, we have burned arginine and phenylalanine to investigate the potential formation of arginine-based HCAs. The present study attempts to isolate and characterize these potential arginine-HCAs.

Mobile Application For Biosensor Colorimetric Analysis, Eui Bin You

Honors Theses

Inexpensive paper-based biosensors can be valuable screening tools to test for various illnesses, but it is often challenging to design them to produce a visual change that can easily be identified by untrained users. This research examines one method of compensating for the lack of distinct visual cues by developing and testing a mobile application that uses a machine learning algorithm (k-Nearest Neighbors) to analyze a picture of a sensor and determine whether it shows a positive or negative result. The machine learning algorithm was trained on a set of labeled sensor images and k-fold cross-validation was used to analyze …

The Ethics Of Environmentalism For The Individual Consumer, Molly Collins

Honors Theses

Climate change harms the well-being of humans. It is the poor choices of individual consumers that contribute to climate change. I argue that it is immoral to cause harm to others, thus climate change is an ethical dilemma for individual consumers. I begin with a pluralistic discussion of harm, before discussing the duties of individuals to make choices that will mitigate the current harms of climate change and the wrong moral assumptions that individuals make regarding their contribution to climate change. I discuss the principles of ethical consumerism, specifically in housing, food, and transportation. Lastly, I argue that climate change …

Fluctuations In Oil Prices And Its Effects On The Usd-Mxn Exchange Rate, Alejandro Velasco

Honors Theses

Do oil prices affect exchange rates? There is a strong correlation between the changes in oil prices and the fluctuations of the exchange rates. What is the effect of the oil prices on US Dollar- Mexican Peso exchange rate? The US Dollar depreciates whenever the oil prices rise, meaning that the oil prices have an impact on exchange rates (Amano, 1998). Financial analysts and oil industry expertise have seen how prices started to decrease in 2014, and this caused uncertainty affecting other markets and consequently exchange rates. The intention of this research is to demonstrate the correlation that exists between …

The Effects Of The One-Child Policy On Household Financial Decisions, Sylvia M. Xu

Honors Theses

The Chinese One-Child Policy, enacted in 1979, was an attempt to decrease the population growth rate following a period of massive social and political confusion and uncertainty. While the policy was beneficial to curbing the population growth in China, it also introduced unintentional consequences, including sex imbalance, and other demographic differences. The goal of this paper is to examine the economic behavior and financial decisions of son-families and daughter-families across different provinces and regions of China, which have varying levels of sex imbalance, as a result of a cultural preference for sons. These financial decisions include the household saving rate, …

Missing The Trees For The Forest: The Socioecological Significance Of Dispersed Farmland Trees In Northern Ethiopia, Jacob A. Wall, Travis W. Reynolds

Honors Theses

Scattered trees are prominent features in the agricultural landscape of the Ethiopian highlands. The dry Afromontane forests of the Amhara Region in northern Ethiopia have faced centuries of deforestation - the FAO estimates only 3% of the region is forested today. The remaining landscape has been largely converted into agricultural and grazing lands, with the exception of some limited government-protected lands, as well as thousands of small forest fragments left around Orthodox Churches (“church forests”). But while a growing body of scholarship has highlighted the ecological and cultural importance of church forests and other natural forest fragments, the roles of …

Missing The Trees For The Forest: The Socioecological Significance Of Dispersed Farmland Trees In Northern Ethiopia, Jacob A. Wall

Honors Theses

Scattered trees are prominent features in the agricultural landscape of the Ethiopian highlands. The dry Afromontane forests of the Amhara Region in northern Ethiopia have faced centuries of deforestation - the FAO estimates only 3% of the region is forested today. The remaining landscape has been largely converted into agricultural and grazing lands, with the exception of some limited government-protected lands, as well as thousands of small forest fragments left around Orthodox Churches (“church forests”). But while a growing body of scholarship has highlighted the ecological and cultural importance of church forests and other natural forest fragments, the roles of …

Health Care Agency: Statewide Awareness Of Patient-Centered Care In Maine’S Mental Health Care Facilities, Holly Hogan A

Honors Theses

This research project focuses on patient-centered care (PCC) in the context of inpatient acute psychiatric units. Hospitals have been claiming their renewed outlooks on health-care via PCC. It has become an increasingly popular term to use on hospital websites and in presidential statements. The technologies and practices surrounding psychiatric care have evolved in such a way that patients are more welcomed to have an input in their care. This project discusses the discourse around PCC at Mental Health Care Facilities in Maine. There is no consensus on the definition; the meanings ascribed to it are derived from the individual institutions. …

A Failure To Cooperate: Why Canada, The United States, And Mexico Have Not Developed A Regional Energy Strategy, Timothy Dutton

Honors Theses

Given the push from the private sector, as well as the resource complementarities among the three countries of North America, it is somewhat surprising that North America has not developed an integrated energy strategy based on traditional, non-renewable energy (2000-2016). How should we understand this puzzle? The answer lies in domestic forces and the structure of national preferences. Using liberal international relations theory, this thesis presents a two-step argument: first, the election of pro-green political parties has in each country led to a convergence of preferences for climate action. Essentially, as each one came to power, the win-set for a …

Entering Into Dialogue With Pope Francis' Laudato Si: On Care For Our Common Home, Sarah Jeanne Shimer

Honors Theses

Pope Francis’ 2015 encyclical Laudato Si: On Care for Our Common Home brings together the spheres of science and religion. In this document, Francis puts forth a call for action towards religious and non-religious communities alike to address climate change. The strength of the document lies in the way Francis expresses his call. By drawing on scientific and religious tradition, he situates the encyclical in a broader conversation about the moral obligation for humans to care for the environment. This thesis explores the reception of Laudato Si by religious and environmental communities through political cartoons, written critiques, and personal interviews. …

Negotiating Order In State-Funded Care: Examining The Salience Of Sponsoring Agencies In Maine's School-Based Health Centers, Susan M. Fleurant

Honors Theses

The rising costs of healthcare and increasing awareness about poor health outcomes in the United States has brought the issue of access to primary and preventative care to the forefront of the national public health agenda in recent years. While still a relatively small part of the U.S. health care delivery system, the integral place of school-based health centers is becoming increasingly apparent, particularly in low-income, medically underserved communities. Previous scholarship that using quantitative measures demonstrates that school-based health centers are effective and address the stark racial and socioeconomic health disparities that persist. Yet, this work neglects many of the …

Campaigning On Youtube: Messaging And Online Communication In The 2016 Presidential Nomination Process, Abraham Krieger

Honors Theses

The Internet has become an important media environment in the context of political campaigns. This research examines YouTube, the most popular website for video content, in order to understand how the platform fits into the broader media landscape and analyzes the messaging content of leading candidates seeking the 2016 nomination. It tests several hypotheses about the YouTube content posted by the campaigns of Donald Trump, Marco Rubio, Bernie Sanders, and Hillary Clinton, during the period from the announcement of their candidacies through February 10, 2016. The research finds that campaigns upload varying amounts and types of content and that they …

Pharmaceutical And Personal Care Products Concentrations In The Belgrade Lakes: A Possible Threat To Aquatic Ecosystems And Human Health, Serena Haver

Honors Theses

Pharmaceuticals and active ingredients from personal care products (PPCPs) include prescription and over-the-counter drugs, sunscreen, fragrances, and soaps. Recently researchers have detected PPCPs in surface waters, posing a threat to aquatic biota and human health. These compounds can enter the environment through dumping, direct excretion, or sewage effluent streams. We tested 14 water samples from East Pond, Great Pond, and Long Pond in Maine for the presence of 23 different PPCPs. Of those, we only detected significant levels of caffeine, 1,7-dimethylxanthine, and amphetamine all below 1µg/L. There were no significant differences between any of the three lakes for any of …

Assessing Lakesmart: The Development And Effectiveness Of A Lake Protection Program, Alexa A. E. Junker

Honors Theses

Maine’s nearly 6,000 lakes are a vital resource for the state, generating $6 billion in annual economic activity and sustaining 52,000 jobs. Over the course of the last several decades, this resource has increasingly been threatened by development and related problems, especially nutrient runoff. LakeSmart is a lake protection program designed to stem the flow of nutrient runoff by promoting and rewarding the use lake-friendly landscaping practices.

For this project, I traced the history of LakeSmart from its roots in the Maine Department of Environmental Protection and, through stakeholder interviews and surveys, chronicled its development into the flagship program of …

The Historical Ecology Of Queensland’S Australian Saltwater Crocodile (Crocodylus Porosus), Emily M. Walker

Honors Theses

Human wildlife conflict is a critical aspect of many societies, as it often plays a large role in government decisions. The iconic saltwater Australian crocodile (Crocodylus porosus) is one example of a species that has become the subject of human-wildlife conflict in Queensland, Australia. Decades of intensive hunting in Queensland, beginning at the time of the Second World War, drastically depleted crocodile populations, leading to a federal embargo on crocodile exports in 1972 and their protection in Queensland in 1974. Since protection, populations appear to be recovering with increasing densities in the north and increased sightings along the …

The Effect Of Temperature On The Supply And Demand For The American Lobster (Homarus Americanus) In The State Of Maine, Gaby E. Carpenter

Honors Theses

The Gulf of Maine (GOM) American lobster (Homarus americanus) stock accounts for 90% of the U.S. American lobster landings. This makes it an extremely valuable and important fishery on a national scale, but also to the state of Maine. In the past decade, the fishery has experienced rapid fluctuation in landings and price due to anthropogenic influences of the water temperature in the GOM. Given the economic importance of the fishery, it is important to understand the future impacts of climate change on the availability of lobster and economic consequences of these shifts. A bio-economic model is used in the …

Park Politics: Political Influences On Frederick Law Olmsted & The Creation Of Central Park, Kathryn Chow

Honors Theses

Frederick Law Olmsted, Sr. (1822-1903), renowned landscape architect and journalist, was also a political activist who saw urban parks as a way to facilitate social reform. This study focuses on Olmsted’s role as Superintendent of Central Park (1858-1861), evaluating the impacts of politics throughout his campaign for Superintendent and during the construction of Central Park. Politics, in this study, refers to both the interactions between Republican and Democratic parties, and the interactions between Olmsted and his constituents, in both the government and the intellectual sphere. This study will provide readers with a fuller understanding of how local political disputes, ideas …

The Voluntourism Encounter: Affect, Discomfort, And Transformation In Yaxunah, Caroline Tegeler

Honors Theses

Within the massive tourism and travel industry, the niche market of volunteer tourism has risen recently in both notoriety and popularity with its promises of a more conscious form of experiencing the world and its people. I explore in this thesis project the encounter between volunteer tourist and host community by examining the motivations, expectations, and imagined roles and identities of each side of the voluntourism encounter. The volunteer tourism industry frames voluntourism as a path towards a more personal, ethical and responsible tourism, but has created experiences filled with discomfort for tourists in their encounter with the communities in …

Development Of A Chemical Genetic Screen To Determine Synergistic Compounds With Laromustine In Treating Glioblastoma Multiforme Cultured Cells, Ryan Weeks

Honors Theses

Laromustine is a chemotherapeutic sulfonylhydrazine prodrug used in clinical trials to treat acute myeloid leukemia (AML) and glioblastoma multiforme (GBM). While treatment of AML with laromustine has more demonstrative clinical success, there are enough promising data against GBM to pursue additional pre-clinical and clinical experiments. To determine the synergistic effects caused by treating cultured GBM cells with laromustine and a library of FDA-approved compounds, a chemical genetic screen was developed. To optimize the screen, optimal cultured GBM cell seed density, growth period and maximum well capacity were determined. The treatment period for a lethal dose of laromustine in cultured GBM …

Experimental And Computational Study Of Methylphenylvinylidene And Its Rearrangements, Xi Yang

Honors Theses

In this study, the synthesis and properties were explored of the compound methylphenylvinylidene (MPV), a vinylidene carbene with methyl and phenyl groups as substituents. A phenanthrene-based precursor, 1-(1-phenylethylidene)-1a,9b-dihydro-1H-cyclopropa[l]phenanthrene, was synthesized in three steps and was subjected to photolysis in C₆D₆ at ambient temperature. During photolysis, the MPV carbene rearranged into 1-phenylpropyne via a 1,2-phenyl shift, instead of 1,2-methyl shift, confirmed by photolysis of ¹³C-labeled precursor. This experimental result is consistent with computational results using the CCSD(T)/cc-pVTZ//B3LYP/6-31+G* method. The calculations suggest that the 1,2-phenyl shift in singlet carbene requires 3.8 kcal/mol to overcome …

The Effect Of Cyanobacterium Gloeotrichia Echinulata In The Belgrade Lakes, Maine, Harriet T. Rothschild

Honors Theses

Gloeotrichia echinulata is a cyanobacteria species that has been increasingly forming blooms in oligotrophic lakes in the Northeastern United States. The Belgrade Lakes in central Maine have experienced increasing blooms over the past decades. Long Pond and Great Pond in the Belgrade Lakes region are popular locations for summer tourism and year-round residents. Research into G. echinulata is important to the Belgrade community because of potential effects to water quality, public health, and recreation. Studying G. echinulata bloom density throughout the summer and how it may affect the phosphorous cycle, the nitrogen cycle, and the plankton community will help scientists …

Global Reach, Local Markets: The Challenges Of Leading Global Innovation, Sarah Higgins

Honors Theses

This Global Studies honors thesis addresses how managers and leaders of global firms manage innovation across multiple markets. Current research on multinational corporations provides an understanding of different kinds of innovation and the ways to attend to multiple markets. However, there is less documentation of how these innovation strategies are actually implemented on the ground and the tensions that these efforts might produce. Therefore, my research focuses in particular on the challenges and tensions faced by leaders of global firms as they implement transnational innovation strategies. This study is based upon in-depth interviews with 20 participants who held positions in …

Don't Know, Do Not Resuscitate: A Principle For The Creation Of The Kingdom Of Ends In The Icu, Griffen Isaac Allen

Honors Theses

In the United States today 20% of all Americans die in Intensive Care Units, or ICUs. These were developed in the 50s, 60s, and 70s to centralize medical resources to help treat critically ill patients with new technologies like ventilators, dialysis, and other tools that are now commonplace. This occurred simultaneously with the emergence of individualistic autonomy, understood as the patient's right to dictate their treatment, as the dominant force in medical ethics. Ostensibly both of these developments would seem beneficial for patients. However, the ultimate result is overly aggressive care that strips patients of their dignity and ensures that …