Digital Commons Network^™

Naloxone Access And Opioid Use: A Theoretical Analysis, Caroline Dunsby

Honors Theses

Naloxone, commonly known by the brand name Narcan, is a medication that reverses the potentially fatal effects of an opioid overdose. Amidst the opioid epidemic that has taken tens of thousands of lives each year, many policies have been enacted to increase the public's access to naloxone, allowing non-medical personnel to save lives. There have been two distinct reactions to these policies. Those that support the policies state that harm reduction measures are necessary to save lives. Those that oppose the policies claim that by providing naloxone, states may be increasing risky opioid use - suggesting that naloxone leads to …

A Qualitative Assessment Of Attitudes Toward Environmental-Health Concerns In Vietnamese -Owned And -Operated Salons In The Greater Seattle Area, Cindy Pham Nguyen

Honors Theses

Environmental-health disparities in nail salons lies at a unique intersection of environmental, health, and social justice. Although the nail industry is booming in the United States, business often occurs at the expense of the well-being of nail salon workers. The workforce, many of whom are immigrant Vietnamese women, routinely handles products containing known carcinogens and endocrine disruptors. Furthermore, workers disproportionately experience negative health impacts from working in salons, including respiratory or musculoskeletal disorders. This behavioral study assesses potential variables (demographic background, health, personal behavior, salon management, and external influence) that impact the attitudes of Vietnamese nail salon workers toward environmental-health …

How Race, Socioeconomic Status, And Gender Shape Feelings Of Competition Within The Pre-Med Department At A Small Liberal Arts College, Amanda B. Deming

Honors Theses

This study aims to understand how students of color navigate feelings of competition in the pre-medical (“pre-med”) track at a small liberal arts college. I argue that there are differences in navigational strategies by race, socioeconomic status (SES), and gender. Respondents in my sample (9 women and 6 men) were interviewed for 30 to 60 minutes about their relationships with fellow pre-med students, mentors, alumni, advisors, and professors. The primary findings of this project were that students who are more competitive dominate the culture among pre-med students; less competitive individuals persist through the pre-med track by forming study groups with …

Diversity, Bias, And Student Outcomes, Amanda J. Schmidt

Honors Theses

This paper examines how racially-motivated bias incidents relate to college students’ academic outcomes, and how this relationship differs across race. There is evidence that students’ academic outcomes are negatively impacted by bias, particularly among marginalized groups. This could have severe impacts on equality, overall student success, and future outcomes. I use Colby College student-level data to analyze the effects of bias incidents on both changes in individuals’ GPAs, and differences in probability of retention across individuals. I analyze the effects of one severe bias incident in the Spring of 2009, and the effects of several bias incidents which occurred over …

Assessing A Two-Hit Model Of Schizophrenia: Prenatal Choline Deficiency And Induced Hypofunction Of Nmda Receptors In Male And Female Long Evans Rats, Samuel Gray, Samuel W. Gray

Honors Theses

Choline is an essential dietary nutrient essential to the development and function of the central nervous system. Prenatal choline deficiency alters hippocampal development as well as acetylcholine metabolism, leading to cognitive impairments and attentional and sensory processing deficits into adulthood. MK-801 is an NMDA receptor antagonist frequently used in rodent models of neuropsychiatric conditions, particularly schizophrenia. Acutely and sub- chronically, it causes hyperlocomotion and social withdrawal. One primary goal of the present study were to investigate prenatal choline deficiency induces a biological vulnerability to the motor deficits, anhedonia, and social impairment precipitated by low-dose sub-chronic MK-801 administration in adulthood. Another …

Food System Resilience In The Face Of Covid-19: A Study Of Maine’S Food Sovereignty Movement, Hania M. Lincoln Lenderking

Honors Theses

As the COVID-19 pandemic has exposed the vulnerabilities in the United States’ industrialized food system, the need for a more resilient alternative is stronger than ever. In Maine, food sovereignty - the right of people to determine their own food system - has been enacted at the local level through the adoption of the Local Food and Community Self-Governance Ordinance (LFCSGO). Using unstructured interviews with leaders of Maine’s food sovereignty movement conducted prior to the pandemic, this study aims to link food sovereignty in Maine to the concept of food system resilience. Participants defined food sovereignty specifically in relation to …

Tuition Resets: An Economic Analysis, Claire Mendelson

Honors Theses

American higher education today is defined by rising tuition and decreasing enrollment. As higher education institutions prepare for a looming enrollment crisis, tuition resets – when colleges or universities decrease their sticker price of tuition – are becoming a newly popular strategy. Although much research has been done regarding the economics of higher education and what influences tuition, no quantitative research study has been done on tuition resets. This research study contributes to the existing literature by quantitatively testing the effect of a tuition reset on an institution’s financial health, as measured by net tuition revenue from students and undergraduate …

Le Prix Pour Devenir Médecin Une Analyse Comparative Des Frais De Scolarité Actuels Associés À La Formation Des Médecins En Suisse Et Aux États-Unis, Jack Dillon Scheutzow

Honors Theses

Pour commencer ce travail, nous devons attirer l'attention sur ce qui se passe actuellement dans le monde et qui a bouleversé tant nos vies : l'épidémie meurtrière du coronavirus 2019 (COVID-19). Ce virus, en quelques mois seulement, a provoqué la peur, la panique, et la souffrance des communautés partout dans le monde. Il nous a également montrés que nos systèmes de santé présentent certains défauts, notamment le manque de médecins et de ressources médicales disponibles pour les patients malades. En Suisse et aux États-Unis, spécifiquement, il y a une grave pénurie de médecins, ce qui rend plus difficile pour leurs …

Does Fish Diet Affect Consumer Decisions? A Nutitional And Sensory Study Of Farm-Raised Trout., Sarah Booth

Honors Theses

The focus of this study is twofold: 1) compare the nutritional value of farm-raised rainbow trout obtained from commercial sources, fed different diet regimens with that of wild-caught rainbow trout, and 2) conduct a sensory analysis test on both farm-raised and wild rainbow trout products with a consumer panel understanding their preferences and attitudes to fish consumption.

The data from this study showed a higher PUFA content in fish raised on the Plant based diet. The sensory study results indicate a preference the fish raised on the Conventional diet. While these results are not conclusive because of the known variables, …

Transformation As Desistance Inside: Temporality And Identity Reconstruction Among Men With Life Sentences, Richard Stover

Honors Theses

This thesis is an investigation of destistance strategies among men sentenced to life in prison in a medium security prison in Pennsylvania. Desistance here is defined as the process leading to the cessation of formally deviant behavior. Drawing from life narrative interviews conducted among 22 men, I argue that desistance is intrinsically tied to how inmates conceptualize themselves within the institutional context of the prison and can be expanded to include people who are still incarcerated. I build off of Peggy Giordano and colleagues symbolic interactionist perspective on desistance and expand it to chart how men with life sentences order …

The Relationship Between Nature, Media Use And Psychosocial Well Being In A College Population, Eve Gilles

Honors Theses

Time in nature is associated with a variety of mental, physical and emotional health benefits while the effects of media use on psychosocial well being are unclear. Although our society is increasingly urbanized and technology-focused, there is a lack of research examining the relationship between nature, media and psychosocial well-being. The aim of this research was to explore these variables in a college-age population. Method: 82 participants participated in a survey using measures of Psychosocial Well Being, Media Use and Nature Connection and Exposure. Results: Media use partially mediates the relationship between nature relatedness and social anxiety. Conclusions: There is …

Nanoparticles As Alternative Ceramic Glaze Colorants, Nathan Dinh

Honors Theses

Metallic nanoparticles, including gold and silver, have been used in wide-ranging applications due to their versatile characteristics. These include catalysis, biosensing, imaging, cancer treatments, and art. Due to the phenomenon called surface plasmon resonance, metallic particles change optical properties when sized in the nanoscale based on their composition, shape, diameters, or aspect ratios. In study, these robust nanoparticle systems are applied as an alternative to traditional bulk metal colorants in ceramic glazes.

In this study, the research goals are two-fold: to understand firing mechanism on the gold nanoparticle size and to develop these processes for wider use by regular artisans. …

Universities And Carbon Neutrality: Motivation To Act And How To Create A Domino Effect, Jason Schwartz

Honors Theses

This research seeks to understand why universities, or other small actors, have pledged carbon neutrality, if these reasons are valid, and if there is room to expand upon existing efforts. In answering these questions, I will investigate whether aggressive climate change mitigation passes a cost-benefit analysis, the nature of individual obligations, and how positive duties can spur social action. Finally, I recommend ways universities can create larger change, through trending social norms.

The Long Arm Of Medicine: Creation Of The Turkish Medical Infrastructure, Legitimacy, Governmentality, And The Rockefeller Foundation, Eric Bossert

Honors Theses

During the early Turkish Republic, a goal of the new government was to set up systems that would help develop the country. One of these systems was their medical infrastructure which included medical education, public health, and hospitals. Ever suspicious of foreign investment since the events leading to the decline of the Ottoman Empire, the Turkish government decided to employ the help of the American aid organization, the Rockefeller Foundation because of their seeming lack of imperialistic goals. Turkish government and the Rockefeller Foundation sought to further their aims through cooperation. The Turkish government sought to gain legitimacy for its …

Ethics, Privacy And Data Collection: A Complex Intersection, Matthew S. Brown

Honors Theses

The technology around us enables incredible abilities such as high-resolution video calls and the ability to stay connected with everyone we care about through social media. This technology also comes with a hidden cost in the form of data collection.

This work explores what privacy means and how users understand what data social media companies collect and monetize. This thesis also proposes a more ethical business model that addresses privacy concerns from an individual perspective.

Why Do I Have To Know This? Engineering In A Globalized Society, Caleb Cunningham

Honors Theses

Through a pilot comparative study, this thesis examines the problem-solving of chemical engineering students and chemical engineering faculty. Specifically, the thesis examines the extent to which individuals include global factors (cultural, social, environmental, and economic) into their engineering solutions as specified by ABET. Several hypotheses were investigated in this pilot study: (i) having a study abroad experience would increase the likelihood that participants included the global factors of interest, (ii) the type (PUI, Research Intensive, Unique) of institution students attended would impact how individuals approached the problem, (iii) students with similar career aspirations would approach the problems similarly, (iv) having …

On The Question Of Thinking: A Study Of Heidegger's Later Philosophy, Shishir Budha

Honors Theses

This thesis explores the writings of the 20th-century German philosopher Martin Heidegger to understand what “thinking” is and how thinking needs to be undertaken. I examine Heidegger’s commitments to phenomenology in his early writings, his revaluation of the meaning of truth in traditional Western metaphysics, his criticism of calculative thinking and scientific rationality, his diagnosis of the human alienation and homelessness, and his evocation of the redemptive power of art and poetry through which we can find our place in the world. By questioning through all these themes, I attempt to trace Heidegger’s path towards a deeper and more original …

Crystalline Architecture And Stratigraphy Of Coral Skeletal Density Banding: A Geobiological Record Of Changing Coral Reef Ecology, Kyle Fouke

Honors Theses

Coral skeletal density banding (CSDB), composed of alternating high density band (HDB) and low density band (LDB) layers that comprise the CaCO₃ (aragonite) skeleton of scleractinian corals, are used as chronometers for global paleoclimatic reconstructions of sea surface temperature (SST). Scleractinian coral skeletons have been intensively studied for centuries with detail analysis of the macro- and microscale skeletal structure to establish taxonomic and evolutionary relationships of coral species, mechanisms of biomineralization, and seafloor physical, chemical and biological alteration (diagenesis) of the skeleton. This study is the first to determine the crystalline architecture of HDBs and CSDB stratigraphic …

Gratitude, Resilience And Post-Traumatic Growth Among Kidney Transplant Recipients, Lillie Credle

Honors Theses

Chronic health conditions, such as end-stage renal disease (ESRD), can produce detrimental physical, psychological, and emotional effects (Schulz & Kroencke, 2015). While transplantation helps to alleviate the physical symptoms, other psychosocial problems can remain. The present study sought to investigate whether organ transplant recipients utilize certain strength-based attributes—gratitude, resilience, and post-traumatic growth—when coping with life post-transplant. This mixed-methods study recruited eight (N=8) kidney transplant recipients, who took part in semi-structured interviews followed by a survey. Though quantitative data was limited due to COVID-19 interruptions, the qualitative data revealed evidence of gratitude, resilience, and post-traumatic growth being used by the participants …

Evaluating A Culprit: A Review Of The Biochemical Mechanisms Of Non-Celiac Gluten Intolerance, Callie Cinque

Honors Theses

Non-Celiac Gluten Intolerance (NCGI) has evaded biological and chemical mechanisms since it was first reported in 1978. Celiac Disease, a multi-system immune mediated disorder has long served as the most similar counterpart to NCGI. Less cases of celiac disease are going undiagnosed reflecting an improvement on sensitive and decisive diagnostic tools. However, NCGI has been significantly growing as a diagnosis over the past decade with little match or similarity to the markers found in celiac disease patients. Critical evaluation of NCGI theories, experimentation, and existing hypotheses is necessary. This review seeks to synthesize multiple disciplines of gluten research and enhance …

Associations Between Hookup Culture And Social Group, Ross Abrash

Honors Theses

Differences in hookup culture and behavior were examined across different social groups at the University of Richmond. Specifically, I examined the difference between Greek life members, varsity athletes, and the general student population. The sample consisted of 174 students (123 females, 51 males) from the University of Richmond. The sample was 33.3% Greek life, 25.9% varsity athletes, and 40.8% general student population. I distributed a web-based survey for participants to complete in a quiet place of their choosing. Fraternity members, sorority members, and male athletes scored higher than the comparison group on a measure of personal attitudes towards hooking up. …

Profitability And Corporate Social Responsibility, Alexander Kirk

Honors Theses

This project examines the relationship between net margins and measures of corporate social responsibility for the companies in the S&P 500 index. This is conducted through linear regressions of overall, environmental, social, and governance scores on net margin percentages for firms from their annual 10-K reports filed with the Securities and Exchange Commission. The corporate social responsibility measures were taken from Sustainalytics via Yahoo Finance and combined with dummy variables for Global Industry Classification Standard sectors. Results indicate very limited role in corporate social responsibility measures for predicting net margins, instead favoring sector specific variables as driving net margins to …

Troping For Justice And Joy: A Feminist Rhetorical Study Of Women’S Reproductive Health, Claire E. Noppenberger

Honors Theses

Taking my cues from feminist rhetorical studies, and the enactment of the personal as political, my thick description of women’s reproductive healthcare is focused on my own encounters with these rhetorics through a collection of my experiences through various media. This description adopts an autoethnographic attitude to approach these rhetorics “as pluralistic, subjective, personal, and potentially inclusive,” by using my own position and narrative to frame this rhetorical study. Just as feminist rhetorical studies require meta-reflexive awareness, autoethnography requires the acceptance of “responsibility for our subjective lenses through reflexivity.” My thick description uses the metadata of these media, including the …

Storytelling For Fundraising: Assessing The Impact Of Personal Stories On Donation Behavior, Kate A. Mccarthy

Honors Theses

In fundraising, some nonprofits have sought to channel the power of personal stories by including them in appeal letters. Are stories an effective tool in soliciting donations? In this study, participants read one of three appeals from an unnamed abortion fund. Two conditions contained a personal story, either an “unapologetic” or a “uncontroversial” narrative, about a woman who underwent an abortion; one condition did not include a story. Participants were then asked questions regarding the appeal and the organization before being given a “bonus” dollar, and offered the option of donating a portion of that to an abortion fund. Results …

Design Of New Ruthenium Complexes For Photoactivated Chemotherapy, Lindsey Paul

Honors Theses

Photoactivated chemotherapy (PACT) offers a targeted approach to cancer treatment through selective drug activation. Substitutionally labile ruthenium-based prodrugs undergo ligand-loss when irradiated, producing an unbound ligand and a Ru-aqua complex. We report the synthesis and cytotoxicity of several new ruthenium-centered complexes and their irradiation products for use in PACT. A series of complexes were synthesized in order to study the effects of structural differences on cell viability. Cell viability was tested on T47D human breast cancer cells in the presence of compound to determine cytotoxicity and dose-response. While neither the Rucomplexes nor their ligands demonstrated cytotoxicity, their Ru-aqua dissociation complexes …

“Put Your Phone Down, And Say Hi!” Cultivating Positivity Resonance At Ur, Natalie Szumel

Honors Theses

The goal of this study is to advance our understanding of outcomes related to experiencing positivity resonance and additionally to examine the role of technology as a potential barrier to experiencing positivity resonance (PR). I expect to see positivity resonance associated with physical, psychological, and social well-being, while phone use will predict lower levels of positivity resonance.

This study is unique because it focuses on a college campus population and analyses how their well-being is affected by their social behaviors. This study is especially important for a campus like UR given how segregated and exclusive the student population has become, …

Public Perceptions And Knowledge Of Transplantation, Kimberly Smith

Honors Theses

Objective: Organ transplantation is currently the most preferred treatment method for end-stage organ disease. Despite this fact, the need for transplants is currently higher than the availability of organs, resulting in approximately 20 deaths each day. The objective of this study was to use qualitative research methods to better understand attitudes towards and public knowledge of organ transplantation. Method: Fourteen focus groups with 58 participants were conducted by a research team. Thematic analyses were conducted using a phenomenological framework. Results: Knowledge of the transplant process was found to play a critical role in one’s decision to donate an organ. Individuals …

So What: The Justification Of Morality In Christine Korsgaard’S The Sources Of Normativity, Julian Scott

Honors Theses

Phillipa Foot once described the case of a Sudeten farm boy who, in 1944, had to choose between joining the SS and being executed (Foot 2). Perhaps it is clear that he was right to choose death rather than join such an evil organization. But if he disagreed, what are we supposed to say to him? Suppose he said that he knew the SS was evil and that joining would require him to do evil things, but when faced with the alternative of execution, why did he have to do the right thing?

This problem can be generalized: what are …

The Effects Of Signaling Molecules To Agrobacterium Tumefaciens Tumorigenesis At Plant Wound Sites, Nicole Walker

Honors Theses

Agrobacterium tumefaciens can live independently within soil before infecting its host (McCullen and Binns, 2006). The bacterium infects the plant through the rhizosphere, an area of soil along the plant root surface which contains microorganisms, making up the “external metabolome” (Bais et al. 2006). As these bacteria live in the rhizosphere, they are exposed to a multitude of chemical signals. These chemical signals include several conditions that must be met before the virulence machinery is expressed. These conditions include signaling from phenols and sugars as well as low PO4 levels and low pH. Upon wounding, sugars and phenols are released …

Variability In Antibacterial Activity In The Caribbean Sponge Amphimedon Compressa, Mackenzie Reilly

Honors Theses

Coral reefs are essential ecosystems that provide an abundance of natural resources. Sponges, common reef inhabitants, produce a diversity of secondary metabolites that are known to serve as chemical defenses. Secondary metabolites often have ecological functions, such as antipredator and antibacterial activities. I studied the common Caribbean sponge species, Amphimedon compressa, which is known to be chemically defended. Samples were collected from three sites in Belize, two sites in Grand Cayman, and three sites in St. Croix, U.S. Virgin Islands. To determine whether antibacterial activity varied across broad or local geographic scales, sponge extracts were tested against four bacterial strains …