Digital Commons Network^™

Mouse Embryonic Stem Cells Are Sensitive To The Cytotoxicity Of Nitric Oxide: Biological Implications For Early Embryogenesis, Mckenzie C. Hargis

Honors Theses

The early embryo, before implantation, is at a very vulnerable stage in development where it faces various inflammatory cytokines throughout the implantation process. In this stage, the cells in the blastocyst, the preimplantation stage embryo, must proliferate rapidly for tissue formation. However, it is known that inflammatory cytokines can inhibit cell proliferation. Previous studies have shown that embryonic stem cells (mESCs), the major cell component in the blastocyst, are unresponsive to treatments of tumor necrosis factor ⍺ (TNF⍺) and interferon 𝛾 (IFN𝛾), two inflammatory cytokines involved in the implantation process. Treatment of mESC-differentiated fibroblasts (mESC-FBs) with TNF⍺ and IFN𝛾 in …

Alpha-Gal Syndrome: Molecular Characterization Of Amblyomma Americanum Α-D-Galactosidase In Α-Gal Metabolism And Onset Of Red Meat Allergy, Ahmed A. Mohamed

Honors Theses

Tick-borne red meat allergy is an IgE-mediated delayed hypersensitivity reaction, increasingly widespread in tick endemic areas in the United States of America, and worldwide. Bites from the lone-star tick (Amblyomma americanum) are believed to be involved as the source of the sensitization of humans to the oligosaccharide galactose-⍺-1,3-galactose (α-gal), which is found in most mammal-derived food products, including gelatin, broths, and red meat. The purpose of this study is to functionally characterize the lone-star tick α-D-galactosidase (AGS) enzyme and assess its role in α-gal metabolism. This enzyme cleaves terminal α-galactose moieties from glycoproteins and glycolipids. Hence, I hypothesized …

Impact Of Artificial Intelligence, Machine Learning, And Automation In Operations Management: An Analysis Of Healthcare, Manufacturing, And Retail Sectors, Jasmine N. Kelley

Honors Theses

In this thesis, we study the impacts of artificial intelligence (AI), machine learning (ML), and automation on operations management (OM). We specifically target the industries of healthcare, retail, and manufacturing in our analysis since each sector has distinct dynamics and concerns regarding the structural changes imposed by advancements in AI. We analyze 120 high-quality peer-reviewed journal articles to capture recent research trends in healthcare, retail, and manufacturing. Using respected business analytics reports, we compare academic efforts to industry initiatives. We find that growing interest in AI research in academia is consistent with growing research and development (R&D) investment and patent …

Using Buy And Rent Discrepancies To Predict Real Estate Bubbles, Jonathan K. Niehaus

Honors Theses

The cost of housing is one of the biggest recurring expenses Americans face. Real estate is also one of the largest asset classes of investments today. The decision of whether or not it is the right time to purchase a piece of residential real estate can be difficult for the everyday person as well as professionals. With the recent downturn of 2008, many people are reminded that the price of houses can spiral upward, and if one bought at the wrong time, their house could lose a tremendous portion of its value. This study focuses on looking at different economic …

The Impact Of Big Data On Audit Evidence And The Level Of Assurance, Sachin Yadav

Honors Theses

This study seeks to establish the relationship between Big Data and its impact on the quality of audit evidence and the level of assurance perceived by the end-users. Currently, auditors rely on sampling to provide reasonable assurance that a company’s financial statements are materially in accordance with a country’s Generally Accepted Accounting Principles (GAAP). With Big Data, auditors can minimize the risk posed by sampling, and therefore, provide a reasonable level assurance. The present study examines financial statement users’ perceptions of the level of assurance when auditors present unqualified opinions using Big Data during the audit engagement. It observes this …

The Effects Of Light On The Bacterial Biomass Of Decomposing Leaf Litter In Freshwater, Savannah L. Underwood

Honors Theses

Recent evidence has suggested that the presence of light (and in conjuction, periphytic algae) stimulates the growth and production of bacteria on decaying plant litter. However, the current method of measuring bacterial biomass, flow cytometry, drastically underestimates the bacterial biomass levels associated with litter samples. To determine and correct for this underestimation, the present study determined conversion factors using direct counting methods via epifluorescence microscopy. These conversion factors were then applied to flow cytometry counts for seven different studies. The studies analyzed the effects of light and other covarying factors on the bacterial biomass associated with various samples of leaf …

Determining The Association Between Religious Participation And Spirituality And Diet And Physical Activity Behaviors In African Americans Of Mississippi, Nidhi Shrestha

Honors Theses

According to CDC, African Americans experience higher rates of chronic diseases when compared to other ethnic groups. Focusing on religiosity and spirituality may benefit the health status of this minority group where advanced healthcare facilities are not easily assessable. The purpose of this research is to 1. Examine demographic factors related to religiosity/spirituality factors among a sample of African American Mississippians; and 2. Determine the correlation between their religiosity, spirituality, and health behaviors. The study uses the data collected by the Mississippi INBRE Telenutrition Center at The University of Southern Mississippi (USM). Participants for this study were recruited from May …

Crime Television Viewership And Perceived Vulnerability To Crime Among College Students, Madison S. Seymour

Honors Theses

This study focused on college students’ viewership of the crime drama television shows NCIS, Law and Order, Criminal Minds, and CSI as well as students’ perceived vulnerability to crime. The aim of the study was to determine if there is a relationship between the viewing of crime dramas and perceived vulnerability, based on the theories of mean world syndrome and cultivation. The study also examined the platform viewers used to watch crime dramas, whether that was streaming services or other options such as cable or satellite television. The chosen platform was also compared with perceived vulnerability to crime.

To collect …

The Effects Of Disease Contamination On Memory For Touched Objects In Older Adults, Jessica M. Runnels

Honors Theses

Recently it has been shown that individuals have better memory for objects that have been touched by an individual with a contagious disease relative to an individual with a non-contagious disease or who is healthy (Gretz & Huff, 2019). This pattern has been suggested to occur due to the activation of the Behavioral Immune System (BIS)—an avoidance-based system designed to thwart sources of potential pathogens. The BIS has been suggested to operate through an evolutionary-based mechanism in which avoidance of pathogens increases the likelihood of survival, increasing reproductive success. Given this approach, an important question is how the activation of …

Investigating Roles For Rna Turnover Processes In Cell Signaling Through Drosophila Melanogaster Genetic Mosaics, Sudiksha Rathan Kumar

Honors Theses

The process of cell signaling is vital in organisms for proper development as it determines the fate and function of cells. This process is highly regulated by myriad interactions between signaling pathway components and gene expression mechanisms. RNA turnover is a type of RNA processing that degrades RNA. It plays an essential role in homeostasis and environmental changes; however, its influence on signaling pathways is currently unknown. In the present study, the effect of RNA turnover processes on cell signaling was analyzed using the genetic mosaics in Drosophila melanogaster. Fly mosaics were created by breeding RNAi lines targeting cellular …

Regulation Of Weak Acid-Dependent Cell Death By The Msaabcr Operon During Biofilm Formation Of Staphylococcus Aureus, Sarah-Elizabeth M. Polley

Honors Theses

Staphylococcus aureus is a dangerous human pathogen and a leading cause of both nosocomial and community-associated infections. Infection by S. aureus is a growing health concern due to the emergence of antibiotic resistance and the capability to form robust biofilms. Major constituents of the biofilm extracellular matrix are demonstrated to be released via controlled autolysis of a subpopulation of the biofilm. As indicated in past studies, the programmed cell death (PCD) of S. aureus grown in a biofilm microenvironment is potentiated by the buildup of acetate, a byproduct of glucose metabolism, which causes cytoplasmic acidification. Furthermore, it has been shown …

Effects Of Sexualized Images In Media On Attitudes Toward Public Breastfeeding, Hannah J. Powell-Yost

Honors Theses

Although breastfeeding is known to promote both physical and emotional health in both infant and mother, many women are hesitant to breastfeed in public due to perceived attitudes toward public breastfeeding. This research explores the relationship between frequent exposure to sexuality in mass media and people's positions regarding breastfeeding. It was hypothesized that sexualized portrayals of the female body perpetuated in mass media would negatively impact individuals’ attitudes toward breastfeeding. No significant correlation was found between media exposure and negative attitude toward public breastfeeding. However, a few interesting results were observed. Individuals who responded positively to sexual media were more …

Examining School Safety And Security: A Situational Crime Perspective, Jessica A. Barnett

Honors Theses

In recent years, an interest in focus of research addressing school safety and security has increased; however, this literature lacks a cohesive theoretical perspective for addressing solutions to school crime and violence. The purpose of this study was to perform a systematic review of the literature on school safety and security. Then, analyze this literature in light of the situational crime prevention perspective. A literature search using Web of Science yielded 45 eligible studies. Results indicated that each of the 45 articles could be organized into one of the five mechanisms of Situational Crime Prevention: increasing effort, increasing risk, removing …

“More Beautiful Than God!”: Hair And Makeup Design For Eugene O’Neill’S Ah, Wilderness, Jackson L. Jones

Honors Theses

This thesis follows an undergraduate theatre designer’s process of designing and realizing hair and makeup for the University of Southern Mississippi’s Spring 2020 production of Eugene O’Neill’s Ah, Wilderness! The student conducted a thorough script analysis, researched Edwardian style and society, and collaborated with the production’s artistic team to produce effective hair and makeup designs and fulfill practicum requirements.

Evaluating Biogenesis Of 5’-Tailed Mirtrons, Jonathan D. Hoover

Honors Theses

MicroRNAs are 22 nucleotide, non-coding RNAs that serve as substrates for Argonaute proteins to induce RNA interference pathways. Intron-derived miRNA precursors called “mirtrons” have been identified and classified primarily through deep sequencing methods. Unlike most miRNAs, mirtrons are derived from splicing events and also exhibit high levels of post-transcriptional nucleotide addition to hairpin precursors. Most relevant among these modifications is 3’ uridylation as it inhibits mirtron biogenesis in multiple model systems. Mirtrons may also possess additional nucleotides adjacent to the pre-miRNA hairpin at the 3’ and/or 5’ ends. These nucleotide “tails” are removed prior to Dicer cleaving the hairpin. In …

Learning To Love Bats, Bethany J. Lawson

Honors Theses

Throughout history, bats have often become entangled in various myths and legends that have negatively influenced human perceptions of bats. Media outlets often sensationalize the relationship of bats to novel diseases, which also creates negative perceptions of bats in the human imagination. Bats are beneficial to our ecosystems and provide pollination services, seed dispersal, and insect control. However, bats are currently facing a variety of life-threatening issues, such as habitat destruction, fatalities at wind energy sites, climate change, and most notably, white-nose syndrome – a disease that has killed millions of North American bats in the past decade. With bats …

Assessing The Role Personality Plays In Puppy Raisers And Guide Dogs In Training, Cassidy D. Wood

Honors Theses

Several factors affect how guide dogs in training fare during the period before the dogs are paired with their future handler. One factor that has not been researched in the past is personality compatibility between the puppy raiser and the dog in training. For the needs of the visually impaired community to be met, guide dog schools need to efficiently train and match dogs to handlers without the dogs failing. To help reduce the number of dogs that fail guide dog training, this study suggests the assessment and comparison of personality for the dog and potential puppy raisers to better …

Language Maintenance And Cultural Identity: Case Studies Of Filipino Immigrant Families In Mississippi, Joy Cariño

Honors Theses

No abstract provided.

Motion Elicits Emotion, Emma Denson

Honors Theses

No abstract provided.

The Conservative Case For Climate Change Belief: Effects Of Theme And Source Characteristics, Alicia Brown

Honors Theses

No abstract provided.

Identifying Drought Stress Tolerance Characteristics In Brassica Carinata Lines At Germination, Sarah Frey

Honors Theses

No abstract provided.

The Effect Of Family Structure And Mental Health On Childhood Bullying Behaviors, Kierstynn Hunter

Honors Theses

No abstract provided.

Effects Of Tcdd On B Cell Populations In Various Anatomic Locations In Eae, Amye Mcdonald

Honors Theses

No abstract provided.

"He's Going To Play": The Influence Of Timing In Return-To-Play Decisions, Seth Lenoir

Honors Theses

No abstract provided.

A Look Into The Impacts Of Tele-Optometry Expansion, Anna Hulsey

Honors Theses

Objective This study aims to assess the health and economic costs and benefits to society and patients resulting from the expansion of telemedicine into online refractive exams and to determine the likelihood of potential consumers to utilize such services. Methods A paper survey was distributed at the Inaugural Cempa Health Fair in October of 2019 to both vendors and participants. 105 responses were used to evaluate personal perceptions, practices, and likelihood across a diverse range of demographics. Responses were then entered and analyzed using descriptive statistics and percentages/frequencies. Results Results showed respondents were most attracted to online refractive exams due …

Molecular Dynamics Simulations Of Apolipoprotein A1 In Ionic Liquids, Benjamin Smith

Honors Theses

High-density lipoprotein function is essential for the healthy processing of fats in the blood. The function of these proteins is determined by their conformational structure of chains of amino acids. Certain ionic liquids have been shown to interact with individual amino acids to affect the tertiary shape of the protein. These interactions can disrupt the native hydrogen bonds between amino acids which can either promote folding or denaturing of the protein. Our work focused on apoA-1, a high-density lipoprotein that binds to cholesterol for efflux from the body. We studied this protein in different ion-based liquids with sodium, chloride, and …

Forest Kindergarten And The Perception Of Parents, Rebecca Boyer

Honors Theses

This study investigates one public school forest kindergarten in the southeastern U.S. The purpose of this study is to determine the perception of parents of a kindergarten classroom context that is somewhat unique for U.S. public schools (forest kindergarten). The researcher believes that there is a unique perception that parents of forest kindergarten students have, and this study seeks to identify and describe them in order to inform 1) the participants and participating school system so that they can make informed decisions for this and future school-context reform models, and 2) the education research community at large so that U.S. …

African Spirituality As Female Empowerment In The Works Of Yvonne Vera And Toni Morrison, Annie Dockery

Honors Theses

This thesis will use close reading and postcolonial and feminist criticism to argue that Africans and African-Americans, and consequently the works of Zimbabwean author Yvonne Vera and African-American author Toni Morrison, are connected by memory and rememory, including spirituality, generational trauma, oral tradition, and ritual reenactment and that this connection comes through the Middle Passage. The works of both authors reveal a transatlantic tradition of Black women employing African spirituality to challenge or overcome what bell hooks calls the oppressive systems of imperialist White supremacist capitalist patriarchies; however, despite the spiritual link between the peoples, Africans and African-American culture can …

Development Of An Auto-Bioluminescent Lung Cell Line For Evaluation Of In Vitro Effects Of E-Cigarette Compounds On Normal Cell Proliferation, Olivia Morrison

Honors Theses

The effects of smoking have long been studied; however, with the rise of electronic cigarettes there is a growing interest in the effects of this smoking substitute. Marketed as a safer alternative to tobacco cigarettes, the popularity of electronic cigarette (e-cigarette) use has dramatically increased. This has demanded regulatory methods to be put into effect, however, scientific study is only beginning on the new fad to determine the impacts of its use on the human body. The present study aims to examine the biological effects of lung cell exposure to tobacco alkaloids found in electronic cigarette filling solutions. We hypothesize …

Complex Conversations: A Creative Exploration Into Language Used Over Direct Messages On Social Media Platforms, Arden Craft

Honors Theses

This paper details a series of paintings that explore how the language used virtually over direct messages (DMs) on social media platforms can allude to how complex notions of gender, violence, and behavior function in reality. This research questions how forms of communication or interaction exist within different spaces and contexts, as well as how the recontextualization of language can disrupt power and produce new forms of interpretation. This paper acts as a secondary source of knowledge in relation to the paintings under review and provides further explanation of their conceptual motivations. In particular, the paintings engage with Sara Ahmed’s …