Digital Commons Network^™

Novel Biomarker Discovery In Multiple Sclerosis, Manisha Gangasani

Honors Theses

Multiple Sclerosis (MS) is a chronic neuroinflammatory disorder affecting the brain, spinal cord, and optic nerve. Patients experience cognitive, motor, autonomic, and emotional symptoms that often overlap with other neurological conditions, making early diagnosis challenging. Current diagnostic criteria require evidence of lesions with dissemination in time and space. Racial disparities in MS outcomes are well documented, with Black individuals often exhibiting greater disease severity, higher relapse rates, and increased disability compared to White individuals. These differences likely reflect a combination of genetic, biological, environmental, and healthcare access factors, underscoring the need to improve early diagnosis and reduce inequities in care. …

Red 40 Riot: An Interdisciplinary Perspective On The Fight For Food Additive Regulation, Margaret Q. Gray

Honors Theses

This paper explores the chemical, business, and governmental influences that impact the perception and future of Red 40. This inquiry was inspired by the increasing trends towards health-conscious consumer preferences and the 2025 Red 3 ban. This thesis examines foundational research, modern sources, and public-facing articles to create a comprehensive understanding of both sides of the argument in support of and against regulation. The paper concludes that a three-pronged approach would be ideal to target each key perspective included: chemistry, business, government. The approaches include confirming chemical research method validity, encouraging governmental regulation, and corporate accountability and enforcement. The paper …

The Oncoming Light: An Experiential Approach To Psychological Exposition Through Dialogue-Driven Narrative, Benjamin G. Dewitt

Honors Theses

Narrative is a lens through which we understand ourselves, our histories, our futures, and our ties to those around us. Narrative form has undergone vast transformations over time, and in the case of “postmodern” literature, pushes the boundaries of form into the experimental, questioning the truth of knowledge itself. While these experimental works can give rise to uniquely powerful emotional experiences, some components of narrative, when abandoned, may only hinder the immersion of the reader. This thesis evaluates several experimental, dialogue-driven narrative works against these components: linguistic, literal, emotional, and intellectual significance, in a hierarchy of importance as proposed by …

Synthesis Of Novel 1,2,3-Triarylnaphthalenes Via Intermolecular Dehydro-Diels-Alder Reaction, Ethan C. Dailey

Honors Theses

The photo-dehydro-Diels–Alder (PDDA) reaction is a useful method for the construction of substituted naphthalene derivatives from acyclic precursors. While intramolecular variants of this transformation are well established, intermolecular PDDA reactions remain rare due to challenges associated with controlling reactivity under photochemical conditions. Previous studies suggest that electron-withdrawing substituents can promote intermolecular cycloaddition by increasing alkyne polarization and stabilizing reactive intermediates. In this work, the effect of enhanced electron-withdrawing character on intermolecular PDDA reactivity was investigated through the incorporation of a 2,3,5,6-tetrafluoropyridinyl substituent. Corresponding alkyne substrates were synthesized and subjected to photochemical conditions, resulting in the formation of 1,2,3-triarylnaphthalene products. The …

Inequity In Education Through The Lens Of Social Studies Curriculum Using Studies Weekly, Emma Roy

Honors Theses

This study examines the representation of the Civil Rights Movement within the Studies Weekly elementary social studies curriculum and evaluates its alignment with culturally relevant pedagogy, critical race theory, and civic education frameworks. Through a qualitative content analysis of twelve assessment questions and accompanying lesson materials, the findings reveal consistent patterns of oversimplification, limited historical nuance, and an overreliance on factual recall. Key themes including systemic racism, collective activist, and diverse historical perspectives are minimized or omitted altogether. These omissions contribute to what scholars identify as curriculum bias, where dominant narratives are privileged while marginalized voices are unheard. The results …

Podcasting As A Marketing And Communication Modality: Exploring Its Impact On Potential New Members’ Satisfaction, Attitudes, And Decision-Making In Utc Sorority Recruitment, Britain Meyers

Honors Theses

This study explores podcasting as a marketing and communication modality within the context of sorority recruitment, specifically examining its impact on Potential New Members’ (PNMs) preparedness, satisfaction, attitudes, and decision-making. Centered around Scrappy’s Sorority Scoop, a four-episode podcast created by the University of Tennessee at Chattanooga 2025-2026 Panhellenic Council, this research investigates how podcast engagement influences the recruitment experience. Using qualitative interviews with eight participants who both joined a Panhellenic chapter and listened to the full podcast series prior to recruitment, the study identifies key themes related to the podcast’s effectiveness. Findings indicate that podcasting enhances PNMs’ understanding of the …

Calibrating Human Trust In The Age Of Generative Ai: An Examination Of Ethical And Social Challenges, Abigail M. Mondido

Honors Theses

Generative AI (GenAI), a set of AI technologies with the ability to generate original, human-like outputs, is beginning to transform the way that information is distributed, composed, published, obtained, analyzed, and consumed. GenAI has seen massive adoption by internet users, businesses, and organizations in recent years despite the persistence of major ethical concerns and social implications. In particular, existing research has identified multiple critical trust-related issues associated with AI in general, including widespread mistrust and distrust, overreliance on AI, and a lack of trustworthiness of AI. There remains a need for a broader understanding of these issues as they relate …

Belonging, Governance, And The Future Of The Nation: Rethinking Citizenship In Tribal Nation Communities, Meadow Carroll

Honors Theses

Tribal citizenship is often framed as a question of identity or legal status, but it functions more fundamentally as a structure of governance that determines who participates in political life and whether nations can sustain themselves over time. This study compares the citizenship frameworks of the Cheyenne and Arapaho Tribes and the Cherokee Nation to examine how different enrollment criteria shape political participation, demographic continuity, and institutional capacity. Drawing on tribal constitutions, enrollment materials, governance records, and voter participation data, the analysis demonstrates that citizenship systems produce measurable differences in how tribal governments function in practice. Systems based on fixed …

Skill Growth And Development In An Honors Experiential Learning Course, Julia D. Lyashevskiy

Honors Theses

Problem-solving skills are crucial for students in both schoolwork and the workforce as they help individuals and groups work through obstacles and come up with solutions to a problem. To help prepare students, the Innovation in Honors Lab at the University of Tennessee at Chattanooga is a hands-on, interdisciplinary course that provides an experiential learning opportunity to practice skills while working directly with community partners to find and solve a local issue. This research tracks the development of six specific skills that students use throughout the class. The skills included communication, creative thinking, decision making, problem solving, conflict resolution, and …

Hardware Integration Of Preamble Based 802.11a Wi-Fi Frame Location For Usrp Radios, Nicholas P. Margavio

Honors Theses

Internet of Things (IoT) refers to a network of devices that can exchange information over the internet, and its deployments are projected to reach 30.9 billion by 2025, with most lacking encryption. One solution for these unencrypted devices is to use Specific Emitter Identification (SEI). SEI exploits distinct, native, and unintentional features of a radio’s signal to identify it and enhance wireless network security uniquely. For example, IEEE 802.11a Wireless-Fidelity (Wi-Fi) radio waveforms have a fixed structure that occupies the first 16 microseconds, from which SEI features can be extracted and used to identify the originating radio. By removing the …

Evaluating The Effects Of Urbanization On Meiofauna Biodiversity In Chattanooga’S Lentic Ecosystems Through Gis Applications, Keyle M. Bryant

Honors Theses

Urbanization is a leading driver of biodiversity loss in freshwater ecosystems, yet its effects on meiofauna—microscopic invertebrates that serve as key bioindicators of ecosystem health—remain poorly understood in lentic environments. This study evaluated the effects of urbanization on meiofaunal biodiversity in ten lentic waterbodies across Hamilton County, Chattanooga, Tennessee, by integrating environmental DNA (eDNA) metabarcoding, in-situ abiotic measurements, and Geographic Information Systems (GIS)-based land use analysis. Water samples were collected between January and April 2023 and processed using 18S rRNA amplicon sequencing to assess biodiversity as richness (amplicon sequence variants or ASVs, phylogenetic diversity or PD, and community composition). Land …

Dissociation, Anxiety, And The Vestibular System: Understanding The Impacts Of Anxiety, Panic, And Dissociation On The Vestibular System, Julian Achata

Honors Theses

Previous research indicates that vestibular dysfunction is associated with symptoms of anxiety, panic, and dissociation. The present study will investigate anxiety, panic, and dissociation symptoms and identify the connections between reported symptom severity and vestibular functionality. This study will focus on three different hypotheses: 1) higher levels of dissociation will correlate with increased vestibular disruption; 2) higher levels of anxiety will correlate with increased vestibular disruption; 3) higher levels of panic will correlate with increased vestibular disruption. Six virtually administered self-report measurements were used to identify the variables: Beck Anxiety Inventory (BAI), Depersonalization Derealization Inventory (DDI), Dissociation Experiences Scale-II (DES-II), …

Red, White, And Broke: A Call For Accountability In Government, Mary A. Scott

Honors Theses

This study examines the scale of waste, fraud, and abuse in U.S. federal spending. The purpose of this research is to clarify how fiscal management in the federal government is intended to operate versus how it actually functions. Using a combination of conceptual analysis, existing literature, case-based evidence, and data analysis, findings suggest that the persistence of oversight failures arises from weak implementation, limited enforcement authority of oversight bodies, and an emphasis on recovery rather than prevention practices. This study contributes to the broader discussion of public finance by providing an accessible framework to understand why the foundational federal principle …

A Meta-Analysis Of Endometrial Cancer Metabolites As Potential Non-Invasive Biomarkers, Makenna K. Johnson

Honors Theses

Endometrial Cancer (EC) is the most prevalent gynecological cancer in the United States and causes tens of thousands of deaths. Despite its massive negative impact in developed countries, there currently is no reliable screening tool used to diagnose women. Due to this urgent need for minimally invasive and precise techniques to diagnose this malignancy, the metabolomics field has been at the forefront of current research. An untargeted mass-spectrometry approach is used by many researchers to form an initial hypothesis as to which metabolites are key in identifying EC cases. However, there are sometimes inconsistencies between studies. A meta-analysis approach examines …

The Impact Of Palm Cooling On The Physiological And Cognitive Function Of Aerobically Trained Individuals, Katherine L. Tibbs

Honors Theses

Background: Cooling strategies have been shown to combat the harmful effects that an increase in body temperature can potentially cause, and palm cooling in particular has been adopted due to its effectiveness in mitigating muscle fatigue during exercise. While there is clear support that this improves muscular strength and endurance, there is a lack of research on the impact palm cooling has on the mental aspect of physical activity. The purpose of this study was to investigate the cognitive and physiological effects of palm cooling on aerobic exercise performance. Methods: Ten aerobically trained participants between the ages of 18-35 were …

Neither Academy Nor Convent: Reconciling Religious And Feminist Readings Of Mary Astell, Hannah E. Brown

Honors Theses

Mary Astell is frequently interpreting through competing frameworks: as either a feminist advocate of women’s rational autonomy or a religious conservative committed to Anglican orthodoxy. This division reflects a broader tendency in Astell scholarship to separate her intellectual, moral, and theological commitments into distinct and often conflicting domains. This paper argues that such fragmentation is not grounded in Astell’s own philosophy but is instead the result of interpretive assumptions—particularly the view that intellectual autonomy and religious obedience are incompatible. By examining Astell’s account of reason, education for women, and spiritual development, this paper demonstrates that these elements form an integrated …

Piloting A Pediatric Screener For Assessing Emergent Literacy With Preschool Children, Nafia Sarhadi

Honors Theses

No abstract provided.

Designing A Steel Bridge: A Structural Overview, Andrew Orr

Honors Theses

The American Society of Civil Engineers (ASCE) and American Institute of Steel Construction (AISC) host the Student Steel Bridge Competition (SSBC), a nation-wide competition where students design, fabricate, and construct a model bridge based on a provided rule set. A group of Arkansas State University civil engineering students participated in that competition in Spring 2026.

Datapeer: A Hybrid Interaction Model Web Application Integrating Llms For Human–Llm Collaboration In Data Analysis And Exploration, William I. Bumcum

Honors Theses

DataPeer is a web application that combines open-ended high agency (OHA) and structured low-agency (SLA) interaction paradigms to support human-LLM collaboration in exploratory data analysis. DataPeer integrates a large language model (LLM) with a React frontend and FastAPI backend, allowing both qualitative and quantitative analysis of user-uploaded CSV datasets through a chat-based interface. Users can attach datasets and provide natural language queries, while the LLM provides data analysis to the user. This thesis investigates the integration of LLMs into data analysis workflows and addresses gaps in interaction design and user agency in LLM-driven data tools by offering a responsive interface …

Athena: A Study In Directing, Keean E. Enriquez-Sexton

Honors Theses

A step-by-step look into the directing process at the collegiate level, following a production of Athena by Gracie Gardner from show selection, through rehearsals, all the way to performance. This thesis serves as a case study in directing, detailing the trials, tribulations, successes, and failures throughout the process.

Use Of Electroencephalography To Evaluate Neural Correlates Of Attention In The Oddball Paradigm, Folsom J. Berry

Honors Theses

Electroencephalography (EEG) and Event-Related Potentials (ERP) are tools used to study and analyze cognitive processing. EEG measures neuroelectric brain activity from the scalp, while ERPs are time-locked averages that are used to isolate neural responses to stimuli. The P300 (P3) component (positive waveform elicited at 300 milliseconds (ms)) is the primary ERP component. This thesis project had two main objectives. The first objective was to develop conceptual and technical competency in EEG/ERP theory, data acquisition, and processing. The second objective was to implement the visual oddball paradigm through experimental demonstration. This experiment tested the hypothesis that infrequent target stimuli will …

A Low-Cost Motion Classification System For A Stuffed Animal Using An Imu And Machine Learning, Rachel N. Guynes

Honors Theses

One of the many fields that has seen the integration of robots is therapy. Zoomorphic robots (ZR) are designed to look and behave like animals to assist in Animal Assisted Therapy (AAT) practices. Studies show that ZRs can provide benefits similar to working with an actual animal; however, their high cost limits their accessibility. This thesis documents the process of building a real-time, low-cost motion classification system that can be attached to a stuffed animal to make it more interactive. Using a Random Forest (RF) classifier, the system identifies movements with approximately 81.67% accuracy.

Dementia Detection In Low-Resource Languages: Evaluating Translation-Assisted Transfer Learning For Multilingual Clinical Assessment, Kylar A. Deloach

Honors Theses

Alzheimer's disease (AD) is a growing global health concern, with millions of people affected worldwide and cases expected to rise significantly in the coming decades. Early detection is critical for patient treatment and care, and recent advances in natural language processing (NLP) have shown promise in identifying linguistic markers associated with AD. However, most existing work has focused on English, leaving speakers of other languages with limited access to such tools. This study investigates how effective AD detection models trained on English data are at transferring to Greek, a low-resource language with limited dementia-related speech data available. We propose a …

What Remains, Hailie Adamczak

Honors Theses

What Remains is a balletic contemporary dance work that explores the emotional complexity of growing older, leaving home, and returning to places that no longer feel the same. Rooted in personal experience, the piece examines the tension between memory and identity, questioning whether home is a physical place or a feeling that slowly changes over time. Through movement, music, lighting, and costume design, the work reflects the bittersweet realization that certain people, places, and experiences continue to shape us long after we leave them behind.

The choreography follows a central soloist navigating themes of belonging, conformity, grief, and self-discovery. Structured …

Discovering The Genetics Underlying Speciation Traits In Heuchera (Coral Bells), Tajinder Singh

Honors Theses

Hybridization is a key evolutionary mechanism for generating biological diversity, ultimately shaping diversification and adaptation of plant lineages in natural and agroecosystems.  Our understanding of the frequency, distribution, and significance of hybridization is rapidly increasing, but the external driving forces that dictate why certain species hybridize, and others do not remain obscure. The physical traits that shape gene flow and trait sharing among species are likely to be among the key factors that directly control hybridization. Gene flow in most plants is mediated by pollinating insects and thus by pollination syndromes, which are suites of floral traits that have evolved …

Cleft Palate And The Coordination Of Wnt Signaling And Pax9 In Murine Palatogenesis, Landon Wyatt

Honors Theses

Cleft palate is a common craniofacial birth defect that arises when the molecular and morphogenetic events guiding secondary palate formation lose coordination during a narrow developmental window. In mice, successful palatogenesis requires the paired palatal shelves to grow vertically, elevate above the tongue, and fuse at the midline; disruption of any of these steps can result in clefting. Two important regulators of this process are canonical Wnt signaling and the transcription factor Pax9, both of which contribute to normal palatal mesenchymal growth and patterning during early development. This paper first examines whether altered Dkk1/Wnt signaling contributes to the Pax9-null palate …

“Under The Fig-Tree”: Post-Revolutionary Literature Influences American Government, Clara Kernodle

Honors Theses

The literary context of post-Revolutionary America developed a broad sense of the American character as virtuous, hardworking, and responsible. In the 1780s, three American writers, representing these three categories of literature, penned their perspectives on human character and society, to much commercial success. J. Hector St. John de Crèvecoeur, Royall Tyler, and Philip Freneau described their situations and opinions with candor and wit, helped spark a broad sense of the American character, and influenced the authors of the nation’s founding documents. At the end of that same decade, Anti-Federalist political philosophy drew from an established literary conception of the American …

Analysis Of The Flavonoid Composition Of Honey Using High-Performance Liquid Chromatography, Bryce Phillips

Honors Theses

Honey is a naturally occurring substance that has a complex composition including compounds such as flavonoids, that contribute to potential health benefits. Quantitative analysis of flavonoids in honey can be challenging due to their similar structural characteristics, matrix effects, and chromatographic peak separation issues. This study aimed to establish calibration curves for five flavonoids–kaempferol, luteolin, chrysin, myricetin, and quercetin– to estimate their concentrations in five honey samples from varying geographic origins. Liquid-liquid extraction was used to isolate the flavonoids from honey. High Performance Liquid Chromatography was utilized to establish calibration curves and analyze honey samples. The calibration curves assembled demonstrated …

Picc-Pal: A Support Band For Independent Picc Line Use, Kylie Luker

Honors Theses

This project presents the design and evaluation of PICC-PAL, a wearable assistive device intended to improve independence and usability for patients managing peripherally inserted central catheters (PICC lines) at home. Current at-home PICC line management often requires help due to the fine motor skills needed to connect and secure tubing. This increases reliance on caregivers and introduces potential risks such as infection and dislodgement. Through stakeholder analysis, prior art evaluation, and iterative prototyping, a device was developed to stabilize the PICC line lumen and enable one-handed connection of medical tubing. Throughout the project, multiple design concepts were explored, with the …

Public Sector Employment: An Examination Of The Perceptions Of Potential Employees And The Realities Of Public Sector Hiring Agencies, Davis B. Chambliss

Honors Theses

This study investigates the growing challenge of recruiting Gen Z employees into the public sector, focusing on the disconnect between younger workers’ career preferences and their perceptions of government employment. While prior research suggests that Gen Z values purpose-driven work, stability, and community impact, public sector organizations continue to face hiring shortages and an aging workforce. The research employs a mixed-methods approach, combining a literature review with original survey data collected from two groups: college students and public servants from three states. The student survey generated 119 responses, with 72 qualifying participants, while the public servant survey yielded 30 responses. …