Digital Commons Network^™

Preliminary Study On The Effects Of Akkermensia Muciniphilia On Akt Phosphorylation In Diabetic Pig Models, Brian Ko

Honors Theses

The onset of type 2 diabetes has been shown to affect the Akt signaling pathway, responsible for modulating cellular metabolism. The pro biotic Akkermensia muciniphilia has been recently shown to have an anti-inflammatory, anti-diabetic effect on animals inoculated with it, particularly within the Akt signaling pathway. This preliminary study utilized a twofactor experimental design with streptozotocin-induced diabetes and the presence of Akkermensia muciniphila in pig models in order to elucidate the probiotic's mechanism of action on the disease. Following analysis of insulin-sensitive tissues of muscle, pancreas, and liver, there was observed a mixed response to the presence of the probiotic …

A Critique Of Environmental Rhetoric Used During World Environment Day, William Calderon

Honors Theses

Fixing environmental problems is one of the fastest-growing priorities for young generations. College degrees such as chemistry and environmental engineering contain courses where students can learn how to tackle a variety of problems, from pollution to energy efficiency. Unfortunately, fixing large problems like global warming or plastics pollution will require the help of millions of people, not just those with technical skills. For this reason, environmental remediation is increasingly becoming not just a technical problem, but a communicative and rhetorical problem as well. Social media in particular is crucial in spreading awareness and garnering support for environmental movements. This paper …

Revealing The Role Of Short Chain And Polyunsaturated Fatty Acids As Regulators Of Metabolic Activity And Gene Expression In Ovarian Cancer, Abigayle Ochs

Honors Theses

Abstract

Previous research using the chicken model has provided evidence that a flaxseed-supplemented diet decreases both the severity and the incidence of ovarian cancer. Flaxseed is a source of omega-3 (OM3) polyunsaturated fatty acids (PUFA), particularly α-linolenic acid (ALA). ALA is converted into longer chain OM3s, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which inhibit prostaglandins, thereby inhibiting oxidative stress, inflammation, angiogenesis, and proliferation. The dietary fiber component of flaxseed can be fermented in the gut to produce short chain fatty acids (SCFA). Butyric acid, a commonly studied SCFA, has been shown be an important metabolic regulator by acting as …

Leadership And Intergroup Relations : Which Leader Is More Favorable Or More Effective While Leading Distinct Subgroups?, Jieyi Ding

Honors Theses

While leading distinct subgroups nowadays, leaders need to address intergroup bias and establish beneficial intergroup relations. They could do so by promoting a collective identity that emphasizes commonality between subgroups or an intergroup relational identity that recognizes distinct characteristics of both subgroups and focuses on their dependency on each other as part of the identity. The research investigated the influence of leader's rhetoric and race interacting with moderators like identity distinctiveness threat on leader evaluation and intergroup bias. The results showed a complicated relationship between how much a leader was liked and how effective a leader could be.

Examining The Effects Of Fadrozole, An Aromatase Inhibitor, On Testosterone And Estrogen Production Of Domestic Chicken Embryos (Gallus Gallus), Abby E. Joseph

Honors Theses

The hypothalamic-pituitary-gonadal (HPG) axis is responsible for the production of the hormones testosterone and estradiol, and testosterone is thought to contribute to regulation of the axis through a negative feedback mechanism. Regulation by negative feedback involves the product of a pathway turning off that pathway when enough product is made. However, because the enzyme P450 aromatase converts testosterone to estradiol, estradiol may also contribute to regulation of the HPG axis and other phenomena that have been attributed to testosterone, like the inhibition of immune function. Previous studies have injected birds with an aromatase inhibitor (presumably reducing estradiol production) and shown …

A Comparative Analysis Of Counterhegemonic Environmental-Economic Projects In Latin America And The United States, Dominic Scicchitano

Honors Theses

The objective of this study is to perform a comparative analysis of counterhegemonic environmental-economic projects in the United States and in Latin America. The work builds on research that I conducted throughout my time at Bucknell University concerning a site known as Better Farm, which distinguishes itself as “a 65-acre sustainability campus, artists' colony, animal sanctuary, and organic farm” located in Redwood, New York (www.betterfarm.org). Better Farm functions as a locus for the surrounding community of roughly 700 residents, connecting a variety of persons interested in both formal sustainability education and informal systems whereby community members support each …

Late Devonian Sedimentary Record Of Appalachian Tectonics And Erosion: Geochronology And Geochemistry Of Detrital Muscovite And Zircon From Central Pennsylvania Strata, Cole T. Gardner

Honors Theses

Foreland basin sediment deposition in North-Central Pennsylvania during Late Devonian time records erosion of hinterland source terranes exhumed during regional plate convergence, including the collisional Acadian orogeny. The Catskill clastic wedge preserves a coarsening-upwards stratigraphic succession from marine to fluvial environments associated with sediment progradation and sea-level regression, yet depositional timescales and quantitative provenance data are largely unconstrained.

Detailed facies analysis of eight outcrops spanning >2 km of stratigraphy in Lycoming Co., Pennsylvania documents distinct upsection changes, interpreted to reflect changes in depositional environments consistent with previous sedimentology of the Catskill clastic wedge. Stratigraphy displays a transition from nearshore marine …

What Lies Beneath? : Removal Sampling To Test For Biases In Surface Activity Of The Eastern Red-Backed Salamander (Plethodon Cinereus), Amelia Tedesco

Honors Theses

In light of the current global amphibian extinction crisis from threats such as climate change and disease, reliable and repeatable sampling methods carry heavy importance for assessing North American salamander species.

Cannabinoid Conundrum: A Study Of Anti-Epileptic Efficacy And Drug Policy, Kennedy Dickson

Honors Theses

Cannabis is the most commonly used, cultivated, and trafficked drug worldwide. The use and acceptance of marijuana is evolving rapidly, as indicated by the volume of new State cannabis legislation across the U.S. Many of the changes in state laws have occurred without significant input from medical or scientific communities. Additionally, marijuana policy in the US is convoluted with significant inconsistencies between state and federal law. The status of marijuana as a Schedule I drug under the Controlled Substance Act creates numerous restrictions and issues that impact the industry as a whole. The most promising development has been the 2018 …

What We Could Do: Stories, Jacob D. Ferguson

Honors Theses

A collection of fiction and creative non-fiction—short stories and personal letters—exploring the lives, fears, anxieties, and joys of characters who grew up gay in southern, religious families. (Under the direction of Beth Spencer)

The Developmental And Behavioral Effects Of Early Life Stage Cannabinoid Exposure, Mariegene E. Almand

Honors Theses

As of 2019, marijuana legalization and decriminalization is sweeping the globe. Patients are increasingly using cannabis-derived compounds including Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) for treatment of diseases as diverse as epilepsy, Parkinson’s disease, and cancer. Furthermore, mothers are claiming that CBD oil decreases uncomfortable pregnancy side effects. While the adverse effects of chronic cannabinoid use and of cannabinoids on pregnancy have been previously investigated, the exact function of the endocannabinoid system, and its primary receptors, cannabinoid receptors 1 and 2, involved in producing these outcomes is still unclear. In this study, two strains of zebrafish embryos, namely fli and cnr2-/- …

Microbial Communities Associated With Dragonfly Nymphs Raised In Varying Concentrations Of Amoxicillin, Michelle Basha

Honors Theses

The bacteria on and within an organism make up that organism’s microbiome. Given interest in the use of antibiotics in agriculture and the effect of microbes on human health, more studies are needed on the microbial community composition of different organisms and how it responds to antibiotic use. This study investigated changes in the amount of antibiotic resistant bacteria present in dragonfly nymphs exposed to differing concentrations of amoxicillin. Next generation sequencing of the 16S rRNA gene was used to identify cultures of these antibiotic resistant bacteria. Increasing the concentration of antibiotics the dragonfly nymphs were exposed to resulted in …

The Last Of Anything, Malerie V. Lovejoy

Honors Theses

DR. MARCUS HALL BENNETT is lead archaeologist on a site in Northumberland, England dated after the Norman Conquest. The excavation seems standard until the discovery of Artifact XX.46.8.2, a collection of animal skins covered in writing. To translate the writing, Hall calls in DR. QUINN PRESTON, a linguist studying Middle English as a creole. As Quinn begins to analyze the writing, she realizes they have discovered a new pidgin—a perfect storm of changing language during a time of political upheaval. Through months of study, Quinn understands the text as a history of the tribe leading up to their extinction at …

Teacher Perceptions Of Arts Integration In Lower Elementary School Classrooms, Holly Kate Badger

Honors Theses

In this thesis, I will address the perceptions of elementary school teachers on the use of arts integration as a teaching practice in their classrooms and how those perceptions impact student performance. Throughout my student teaching experience this year, I engaged in a reflective practice of making field notes as I observed, assisted with, and taught arts-integrated lessons in a kindergarten classroom. Additionally, I conducted one-on-one interviews with three in-service teachers at the rural Mississippi elementary school in which I was placed. I made this a mixed methods study by adding a third source of data via an online questionnaire …

Staff Perceptions Of Healthy Eating Opportunities And Choices On A Southern University Campus, Rebecca Gwendolyn Miller

Honors Theses

Maintaining a healthy workforce can help an employer to save money in the long run, due to factors such as fewer health-related absences and higher employee productivity. Obesity, a disease with many factors, is accompanied by many comorbidities. Food and beverage choices can play a strong role in the development of obesity. The purpose of this study was to explore factors that influence staff eating behavior in a large university in the Southeastern United States, using a qualitative research design. Additionally, staff members provided possible solutions to improve the eating environment on the University’s main campus. Using a structured question …

Synthesis Of A Novel Tetradentate Ligand And Its Copper Complex For Redox Shuttle Applications, Joseph T. Vaughan

Honors Theses

With growing energy demands, alternatives to the traditional non-renewable fuel sources are currently being explored. Of these alternative fuel sources, solar energy, particularly dye-sensitized solar cells (DSSC), have garnered considerable interest. Traditional redox mediators within these solar cells have been triiodide/iodide couples, which pose several complications due to their corrosiveness, absorption in the visible range, and efficiency, motivating the development of better redox couples for next generation DSSCs. Thus, transition metal complexes have rapidly gained traction as a potential replacement for this traditional I-/I3- based system. In this study, a novel tetradentate ligand framework and its copper and nickel complexes …

Religion In Education: The Effects Of Political Ideologies On Andalusian Youth, Jessika Brittni Russell

Honors Theses

This study investigates the driving factors behind a student’s choice to take a class on Catholicism, or the alternative social and civil values class, throughout their educational career in Andalusia, Spain. Major sociological theories are used to understand how religion, education, and politics tie together in society, and additionally the impact they have on individuals. In order to understand the personal factors that play into one’s choice to take a class on Catholicism, a survey was created using the platform Qualtrics and afterwards sent out to students in Andalusia, Spain. The study uses a qualitative approach to analyze the data …

The Prc And Its Anti-Drug War: The Opium Suppression Campaign Of The Early 1950'S, Queen Marcela Pierre

Honors Theses

For centuries, China sought to suppress opium consumption within its borders. Following the Chinese Communist Party’s rise to power, the 1950’s drug suppression campaign initiated new attempts to bring about the end of opium’s presence within Chinese society. What led to this campaign’s success is its utilization of different strategies within each region of focus. The combination of strategies used allowed the CCP to eradicate all forms of the opium market in both urban and rural areas where the campaign was active. This thesis examines the methods used during the campaign and how these methods resulted in the campaign’s success.

Sustainability In The Sanctuary: An Analysis Of The Relationship Between Christian Churches And The Environment, Katelyn Campbell

Honors Theses

Paper bulletins, weekly customized song sheets, disposable coffee cups—all parts of a regular communal church gathering on Sunday mornings. Where do these products go after the service is over and the pews are empty? Combining the topics of environmental sustainability and organized religion, this thesis explores how local churches view the intersection of environmental sustainability and faith practices in Oxford, Mississippi. Preliminary research has shown that while many global denominations publicly issue statements supporting environmental practices and encouraging sustainable behavior, often these statements are not effective in directly influencing a local church’s behavior as it relates to implementing environmentally sustainable …

More Than Altruism: An Examination Of Dr. Martin Luther King Jr.'S Involvement In The Chicago Campaign And Protest Of The Vietnam War, Stephanie Poiroux

Honors Theses

This mix-method study examines whether Dr. Martin Luther King Jr.’s writing reflects altruism. Utilizing content analysis, I examined 60 of King’s sermons, speeches, letters, newspaper statements, and telegrams about the Chicago Campaign and the Vietnam War over two separate two-year periods starting from January 1, 1965 to December 31, 1967. King’s documents were scored based on the Altruistic Personality Scale for Leaders and Protest, which was created based on the characteristics of both passive and active bystanders derived from studies written by scholars of psychology. After analyzing the range, complexity, and density of King’s altruism, this study shows that all …

[Female]: A Collection Of Profiles Featuring Influential, Inspiring, Modern American Women Who Have Made History, Tara Lyn Hawkins

Honors Theses

[FEMALE] is a collection of profiles that feature the stories of some of the most influential and inspiring modern American women and how they have influenced the world. The profiles look into the lives and careers of female athletes, entrepreneurs, political figures and entertainers who are currently alive in 2019. Each profile includes dialogue from recorded interviews with the featured women. The idea for this project came from wanting to learn more about the successful, influential role models in my life. To learn about the hardships and odds they overcame in order to achieve their dreams and become the women …

Effects Of Vertical Transmission Of Maternal Antibodies To Mycoplasma Gallisepticum On Growth And Condition Of Eastern Bluebird Nestlings (Sialia Sialis), Mckenzie Xiang Denton

Honors Theses

Mothers display maternal effects to influence the development and success of offspring through processes such as resource allocation. In birds, this occurs largely through the egg yolk with the vertical transmission of antibodies to offspring to protect the vulnerable young from disease. Specifically, poultry and eastern bluebirds across the eastern United States are commonly infected by the bacteria Mycoplasma gallisepticum (MG), for which mothers may produce antibodies against. To test for the vertical transmission of MG-specific antibodies from mothers to nestlings in eastern bluebirds and the associated fitness effects, bluebird boxes were set up and monitored during the field season. …

This Is Your Brain On Music: The Study Of Musical Influence On The Cognitive Mindset And Learning, Allysa N. Lipsey

Honors Theses

This thesis examines the use of musical influence on the brain with an emphasis on the effects on cognitive mindset and learning in mathematics education. It explores the idea of the use of different trials and methods to potentially unlock new knowledge about the brain through listening to music during in-class group work, individual work, and class assessments. It allows for an analysis of the music’s effect on the brain and creates discussion in multiple classrooms and age groups through the eyes of a participant observer in an ethnographic research scenario. By analyzing behaviors of body language, musical taste and …

State And Regional Comparisons Of Breastfeeding Policies And Rates: A National Study, Erin Johnson

Honors Theses

State legislation focused on promoting and supporting breastfeeding is relatively new, beginning in the 1990s. The purpose of this study is to determine if there is an association between state breastfeeding rates and state breastfeeding legislation and other institutional policies. The Centers for Disease Control and Prevention releases breastfeeding report cards with the most up-to-date state breastfeeding rates. These reports are used to examine the relationship between state breastfeeding rates and number of breastfeeding policies passed by a state. Government initiatives, such as Healthy People Initiative, and organizational practices, such as Baby-Friendly USA Inc., are also studied to determine their …

Fungal-Algal Speed Dating: Exploring Symbiotic Potential Of Fungal-Algal Cocultures, Natalie S. Williams

Honors Theses

Symbiotic relationships are widely studied phenomena in the biological world. Of particular interest are the ubiquitous relationships that exist between fungi and photoautotrophs. While much is known about the commonly occurring interactions that persist between fungi and a wide range of terrestrial plants, we are interested in exploring the symbiotic capacity between fungi and earlier diverging lineages of the plant kingdom, notably green algae. We developed an experiment to allow for a medium-throughput analysis of fungal-algal interactions using three model green algae: Chlamydomonas reinhardtii, Chlorella vulgaris, and Penium margaritaceum. With numerous replicated assays, these algae were individually paired with a …

A Study Of The Kratom Alkaloids And Their Binding To The Μ-Opioid Receptor, Reba Elizabeth Ann Chamblee

Honors Theses

Kratom, a plant commonly found in southeast Asia, has traditionally been used for medicinal treatments. Recently, however, the popularity of the drug has significantly increased due to its euphoric effects, leading to it being used as an alternative to illegal opioids. Several alkaloid compounds have been isolated from the leaves of the plant. The main alkaloids seen are the following five alkaloids: mitragynine, 7-hydroxymitragynine, speciociliatine, speciogynine, and paynantheine. Two alkaloids, mitragynine and 7-hydroxymitragynine, have exhibited high potencies and are potentially even more potent than morphine. Previous studies have indicated that the main mediator of the psychoactive effects is the opioid …

Japanese Mascots: Diplomatic Tool, Domestic Escapism, Gwenafaye Mccormick

Honors Theses

In Japan, mascots are not only representatives of sports teams and sugary cereals, but are vital diplomatic tools of communication and domestic tools of escapism. Though a multitude of mascots exist, scholarship on the topic tends to portray the body of mascots as one-dimensional. This thesis analyzes the modern mascot field and provides previously undefined categories for mascots based on their application, as their absence hinders further analysis. These definitions also describe the subversive social space that mascots inhabit in Japanese society and allow the thesis to examine consumers’ relationships with mascots. An analysis of the U.S. and Israeli embassy …

Tracking Using Fusion Of Multiple Inertial Measurement Units, Jacob Reed Mccall

Honors Theses

The objective of this thesis is to determine the effectiveness of fusing data from multiple inertial measurement units (IMU) to reduce bias and noise with an overall goal of achieving accurate tracking, which is the process of locating a body as it moves in a fixed environment. Every sensor is subject to noise, and each sensor has its own unique set of biases. The thesis presents a systematic overview of the sensors used in this research, which feature linear acceleration, angular acceleration, and a directional sensor, to form an inertial navigation system (INS). Sources of noise and bias that affect …

Dworkinian Liberalism, The Right To Pornography, And The Internet, Will Nowell

Honors Theses

In a 1981 journal article, “Is There A Right to Pornography?,” Ronald Dworkin argues that we have a right to ethical independence that includes the right to consume pornography. The purpose of this thesis is to inquire as to whether Dworkinian liberalism does entail a right to specifically internet pornography. This research is primarily focused on Ronald Dworkin’s writings in Justice for Hedgehogs, Sovereign Virtue: The Theory and Practice of Equality, and Taking Rights Seriously to describe the principles and character of Dworkinian liberalism and its philosophical relationship to the question of the right to pornography. This thesis considers contemporary …

Watering The Desert: Azraq, Public Opinion, And Environmental Post-Materialism, Wesley Gerard

Honors Theses

In this thesis, I analyze the physical, political, and societal transformations in Azraq, Jordan, caused by over-exploitation of the town’s aquifer. I also connect the changes I and others have observed in Azraq to two main theories: postmaterialism and its counterarguments, and the tragedy of the commons. In short, postmaterialism argues that societies that have advanced so that citizens do not have to devote their time and money to survival will have larger rates of environmentalism; the tragedy of the commons details the negative consequences of environmental degradation on those living around a common resource. In conducting the study, I …