Digital Commons Network^™

Data Analytics For Sustainable Food And Agriculture Systems, Megan Lord Reavis

Graduate Theses and Dissertations

The increasing concentration of anthropogenic greenhouse gases in the atmosphere is altering the climate, posing a serious threat to global agriculture and food security. Agriculture and food production contribute a quarter of all GHG emissions produced, so there is a critical need to limit emissions in this area while increasing food production to feed the anticipated 10 billion people by 2050. To address the needs of the future, data-driven solutions are needed to guide decision-making and provide support for actionable climate mitigation and survival strategies. Research efforts must be focused on analyzing problems on multiple scales, identifying new ways to …

Multifunctional Programmable Self-Assembled Nanoparticles In Nanomedicine, Yoshie Sakamaki

Graduate Theses and Dissertations

Developing methodologies to control the architecture of nanoparticles (NPs) at the atomic level prevents their inhomogeneity and leads to a variety of expected functions. Rationally designed nanoparticles can either be programmed or crystallized structures into pre-determined structures achieving tunable particle pore size and physiochemistry. In this dissertation, two broad classes of multifunctional nanoparticles are developed, metal-organic frameworks and DNA-NP aggregates.

Metal-organic frameworks are a novel class of highly porous crystalline materials built from organic linkers and metal cluster-based secondary building units. However, applications in bioremediation have not been developed very well especially in applications regarding drug delivery systems (DDS). The …

Sigesn Light-Emitting Devices: From Optical To Electrical Injection, Yiyin Zhou

Graduate Theses and Dissertations

Si photonics is a fast-developing technology that impacts many applications such as data centers, 5G, Lidar, and biological/chemical sensing. One of the merits of Si photonics is to integrate electronic and photonic components on a single chip to form a complex functional system that features compact, low-cost, high-performance, and reliability. Among all building blocks, the monolithic integration of lasers on Si encountered substantial challenges. Si and Ge, conventional epitaxial material on Si, are incompetent for light emission due to the indirect bandgap. The current solution compromises the hybrid integration of III-V lasers, which requires growing on separate smaller size substrates …

Engineering Fluorescently Labeled Human Fibroblast Growth Factor One Mutants And Characterizing Their Photophysics Properties Towards Designing Fret Assays, Mamello Mohale

Graduate Theses and Dissertations

Human fibroblast growth factor one (hFGF1) belongs to a family of 22 FGF members produced by fibroblast cells. Cell signaling during physiological processes of angiogenesis and wound healing occurs when hFGF1 binds to its receptor (FGFR). However, when heterogenous homeostasis is not maintained, fibroblast cells exhibit excessive proliferation which can lead to a myriad of cancers. smFRET is an ultrasensitive distant dependent (1-10 nm) technique capable of resolving such heterogeneity in structural dynamics and binding affinities (Kd). Therefore, we successfully designed and characterized fluorescently labeled hFGF1 tracers which span the visible light region of the electromagnetic spectrum for use in …

Hobby Grade Lithium-Ion Batteries For Spacecraft Applications: Establishing An Automated Electrical Characteristics Testing Procedure For Flight Acceptance Of Non-Space-Grade Small Secondary Batteries, Braidon Hughes

Graduate Theses and Dissertations

Li-ion batteries are widely used due to the large amount of rechargeable energy they pack into a small, light package. This higher energy density makes Li-ion batteries ideal for small satellite applications, specifically CubeSats. CubeSats have grown in popularity in higher level education due to the National Aeronautics and Space Administration’s implementation of the Cube Satellite Launch Initiative, making it easier and cheaper to conduct small, low orbit missions. Because these CubeSats are occupying the same space as a crewed spacecraft, it is imperative that they are safe. There are numerous reports of Li-ion batteries creating fires that result in …

Synthesis Of Polyethylene Glycol-Based Hydrogels And Silver/Gold Nanostructures For Biomedical Applications, Isabelle Ishimwe Niyonshuti

Graduate Theses and Dissertations

This work focuses on the synthesis of biocompatible polyethylene glycol (PEG)-based hydrogels, silver nanoparticles (AgNPs), and silver-gold nanocages (Ag-AuNCs) for biomedical applications. The dissertation includes two parts with Part I on the work of PEG-based hydrogel for wound healing applications and Part II on the work of Ag/Au nanostructures for antimicrobial applications. Part I studies PEG-based hydrogel for the delivery of fibroblast growth factors (FGFs) for wound healing applications, aiming to overcome the challenge of designing hydrogels capable of the sustained release of bioactive FGFs. This research develops new biocompatible anionic injectable hydrogel formulations based on Poly (Oligo Ethylene Glycol …

Interplay Between The Lattice And Spin Degrees Of Freedom In Magnetoelectric And Magnetic Materials, Temuujin Bayaraa

Graduate Theses and Dissertations

This dissertation contains several investigations on the cross-coupling between structural and spin degrees of freedom in multiferroic and ferrimagnetic compounds by means of first-principles calculations and ab-initio-based Monte-Carlo simulations. We start with the reviews of magnetoelectricity, ferrimagnetism, strain engineering, followed by a brief introduction to first-principles computational methods, magnetic effective Hamiltonians, and other techniques that are utilized here. The results section of the dissertation can be divided into two parts. The first half focuses on magnetoelectric effects arising from different sources, while the second half is about the ferrimagnetic nature of materials. In the first part, we examine the epitaxial …

Forced And Unforced Permafrost Changes In The Northern Hemisphere During 1901-2100, Hong Guo

Graduate Theses and Dissertations

Permafrost regions are very sensitive to rapid changes in climate and environment. In recent decades, there has been growing interest to better understand the permafrost degradation over the Northern Hemisphere in the context of human-induced climate change. Understanding permafrost dynamics is not only important for infrastructure but also for environmental protection in cold regions. In-situ permafrost measurements are important for assessing permafrost conditions. However, direct permafrost observations are sparse and asymmetrical in both spatial and temporal coverage. Active layer thickness (ALT) modeling is another approach that can overcome many of these limitations, but the models have large uncertainty in predicting …

Hybrid Two Dimensional Quantum Devices, Joshua Patrick Thompson

Graduate Theses and Dissertations

This thesis describes measurements on hybrid material systems involving two dimensional (2D) materials and phenomena along with the development of a small, hermetically sealed cell. The hermetic cell is designed to assist with analyzing sensitive 2D materials outside of an inert environment. When working with van der Waals materials that are especially sensitive to oxygen or water, it can be difficult to identify usable thin flakes without exposing them to air. To help preserve materials for analysis in air, a capsule was designed that isolates the material in an inert environment. Although the capsule is hermetically sealed, the encapsulated material …

Efficacy Of Spirulina (Arthrospira Platensis) Utilization In Broiler Diets, Garrett James Mullenix

Graduate Theses and Dissertations

Spirulina (Arthrospira platensis) is a cyanobacteria microalgae that has potential as an animal feed ingredient. Five experiments were conducted to further assess its ability to serve as a protein source in broiler diets. Experiment 1 consisted of an amino acid digestibility and apparent metabolizable energy assay. The results indicated that the standardized ileal amino acid levels of spirulina are comparable with typical soybean meal. Experiment 2 assessed the performance and processing parameters of broilers fed 10% spirulina in low crude protein diets, using published digestibility coefficients. Spirulina inclusion improved footpad quality and increased redness and yellowness of the breast, skin …

International Students In The Campus Carry Debate: A Descriptive Phenomenological Inquiry, Andre Richardo Grant

Graduate Theses and Dissertations

This qualitative phenomenological study purposefully sampled 15 graduate international students at a Southern University (SU). Semi-structured interviews were used to determine their perceptions and attitudes regarding the implementation of campus carry policies at the institution. The study aimed to answer the following research questions: How has the implementation of the campus carry policy at SU impacted international students’ perceptions of their experiences at the institution? How has the implementation of campus carry policies at SU influenced international students’ perceptions of the social ecology of the institution? and How did SU formally include international students in the on-campus campus carry policy …

Diversifying Woolf’S Room: Private Spaces And Creativity In The Works Of Willa Cather, Kate Chopin, Gayl Jones, And Alice Walker, Ebtesam M. Alawfi

Graduate Theses and Dissertations

There is a divergence between Woolf’s vision of private physical spaces necessary for creating art and that of some feminists of color such as Alice Walker, Ortiz Cofer, and Gloria Anzaldua. Both Woolf and these contemporary scholars agree on the importance of physical spaces for female artists. However, they disagree on the nature of these spaces. Woolf’s private physical space is a room with a lock on the door whereas these writers’ room is the kitchen table, the bus, or the welfare line. Walker and like-minded writers challenge the narrowness of Woolf’s room because her locked room is a luxury …

Reflective Conversations: Exploring Faculty’S Perceptions Of Reflection To Enhance Teaching Effectiveness, Jonna Lynn Myers

Graduate Theses and Dissertations

The purpose of this pragmatic qualitative research study is to examine the impact of a faculty development program’s reflection component on teaching effectiveness as perceived by the faculty participants. This study utilizes Schön’s (1983) reflective practice, which calls professionals to move from the technical rationality position of development and practice (theoretical and detached) into a reflective position (practical and applicable). Schön contends that this movement occurs by focusing on reflection in the forms of reflection-in-action, reflection-on-action, and reflective conversations. This study specifically examines the reflection component embedded into the inaugural class of the Excellence in Teaching Program (ETP) at pseudonymous …

Longitudinal Monitoring Of Tumor Response To Immune Checkpoint Inhibitors Using Diffuse Optical Spectroscopy, Joel Isaac Rodriguez Troncoso

Graduate Theses and Dissertations

Immune checkpoint drugs have completely changed the way people treat metastatic melanoma and non-small-cell lung cancer. While the impacts of these immunological checkpoints and their suppression on T cell function are well characterized, their consequences on the tumor microenvironment are not. In a CT26 mouse colorectal cancer model, we employed diffuse reflectance spectroscopy to track in vivo tumor microenvironmental alterations in response to immune checkpoint inhibitors. On three separate days, animals bearing CT26 tumor xenografts were given anti-PD-L1, anti-CTLA-4, a combination of both inhibitors, and isotype control. Within the first 6 days, monotherapy with either anti-PD-L1 or anti-CTLA-4 resulted in …

Incorporation Of Zinc In Pre-Alloyed Cuin[Zn]S2/Zns Quantum Dots, Jean Carlos Morales Orocu

Graduate Theses and Dissertations

Since the early 2000s heavy-metal-free quantum dots (QDs) such as CuInS2/ZnS have attempted to replace CdSe, their heavy-metal-containing counterparts. CuInS2/ZnS is synthesized in a two-step process that involves the fabrication of CuInS2 (CIS) nanocrystals (NCs) followed by the addition of zinc precursors. Instead of the usual core/shell architecture often exhibited by binary QDs, coating CIS QDs results in alloyed and/or partially alloyed cation-exchange (CATEX) QDs. The effect that zinc has on the properties of CIS NCs was studied by incorporating zinc during the first step of the synthesis. Different In:Cu:Zn ratios were employed in this study, maintaining a constant 4:1 …

Study Of Thick Indium Gallium Nitride Graded Structures For Future Solar Cell Applications, Manal Abdullah Aldawsari

Graduate Theses and Dissertations

Indium gallium nitride (InxGa1-xN) materials have held great potential for the optoelectronic industry due to their electrical and optical properties. The tunable band gap that can span the solar spectrum was one of the most significant features that attracted researchers’ attention. The band gap can be varied continuously from 0.77 eV for InN to 3.42 eV for GaN, covering the solar spectrum from near infrared to near ultraviolet. Additionally, it has a high absorption coefficient on the order of ∼105 cm−1, a direct band gap, high radiation resistance, thermal stability, and so on. Nevertheless, the epitaxial growth of high quality …

Development Of Aptamer Rolling Circle Amplification Platform As A Vaccine Adjuvant To Control Salmonella In Broiler Chickens, Abigeal Iyabode Omolewu

Graduate Theses and Dissertations

Salmonella has been a major source of concern in public health and food industry. It is the cause of gastrointestinal illness and fever called salmonellosis. Severe cases of salmonellosis have resulted in hospitalization and even death around the world. Salmonella can be found in the intestinal tract of animals including chickens and can be transmitted to human through contaminated food. Hence, it is highly important to find ways of reducing the transmission of Salmonella from chickens to humans. This work is focused on the control of Salmonella in broiler chicken through the development of novel vaccine adjuvant. Two different aptamer …

Development And Characterization Of Monolayer And Sub-Monolayer Intermediate Band Solar Cells, Najla Alnami

Graduate Theses and Dissertations

Intermediate band solar cell (IBSC) is a new generation solar cell that is designed to overcome the main limitation of solar cell power conversion efficiency, which is the non-absorption of low photon energy. Experimental efforts towards fabricating high efficiency and low cost IBSC have not met the predictions of theoretical analysis. Existing implementations of the IBSC design using conventional Stranski-Krastanov (S-K) quantum dots (QDs) have resulted in a degradation in the solar cell device characteristics, which has been found to be caused by recapturing or trapping of excess carriers, low intermediate band material absorption, and increased recombination in the solar …

Gaas Growth On Sapphire Substrates (C And R Plane) For Integrated Microwave Photonics (Imwp), Samir Kumar Saha

Graduate Theses and Dissertations

The microwave signal processing in the optical domain creates new opportunities for information and communication technology (ICT) and networks by increasing speed, bandwidth, and processing capability. IMWP incorporates the functions of microwave photonics components/subsystems in monolithic or hybrid photonic circuits to meet future needs. Sapphire platforms have the potential to integrate all-in-one, for instance, light source, analog signal processing, light detection, CMOS control circuit, silicon on sapphire to achieve high-performance, low-cost mixed-signal optical links etc. Molecular beam epitaxy (MBE) has been used to grow GaAs on sapphire substrates to integrate optoelectronic devices in the same platform.

The initial stage of …

Understanding The Chemical Structures Of Polydopamine, Deborah Takyibea Okyere

Graduate Theses and Dissertations

Polydopamine (PDA) is described as a bioinspired polymer produced by a method involving the chemical oxidation of dopamine in a pH-dependent medium. It has been used for the functionalization of nanomaterials in diverse applications including drug delivery and biosensing because of its strong adhesiveness, functionality is easily modified, and biocompatibility with mammalian cells and tissues. The polymerization process is believed to be initiated by the autoxidation of dopamine to dopaminequinone. However, the repeating units, as well as the final structure of PDA, are not well understood. Hence, this work focuses on the characterizations of the PDA structures during formation and …

Two-Dimensional Black Phosphorus For Terahertz Emission And Near-Field Radiative Heat Transfer, Mahmudul Hasan Doha

Graduate Theses and Dissertations

The main focus of this work is to investigate two potential optical and optoelectronic applications of black phosphorus (BP): the near-field radiative heat transfer in plasmonic heterostructures with graphene and terahertz emission from multi-layer BP photoconductive antennas. When the separation distance between graphene-black phosphorene is much smaller than or comparable to the thermal wavelength at different temperatures, a near-field radiation heat transfer breaks the Planck blackbody limit. The magnitude of the near-field radiation enhancement acutely depends on the gate voltage, doping, and vacuum gap of the graphene and BP pair. The strong near-field radiation heat transfer enhancement of the specific …

Site-Specific Effects Of Lysine Acetylation On Aminoacyl-Trna Synthetase, Hao Chen

Graduate Theses and Dissertations

Aminoacyl-tRNA synthetases (AARSs) are an ancient and highly conserved family of enzymes which can catalyze a two-steps aminoacylation reaction to charge tRNAs with their cognate amino acids, thus playing crucial roles in ribosomal protein synthesis. Naturally, the accurate amino acids and tRNA recognition of these synthetases are essential to the fidelity of translation process. To assure the correct recognition, some of these synthetases have evolved with an editing function to help remove the mischarged tRNAs. In addition to these functions, AARSs are also involved in various biological processes ranging from transcription to translation. Currently, a series of proteomic studies have …

Remixed, Remastered: Investigating Organizational Adaptation In Higher Music Education, Jacob Bruce Hertzog

Graduate Theses and Dissertations

Higher music education presents a unique opportunity to examine change within higher education due to the digital revolution in the music industry over the past two decades. The purpose for conducting this study was to describe, map, and explain the strategies that higher music education programs are using to adapt to the digital revolution in the music industry. This study was grounded in organizational adaptation theory, drawing upon nine well-established theories: population ecology, life cycles, strategic choice, isomorphism, symbolic action, resource dependence, cybernetics, and network theory. Critical concepts of the turbulent environment, environmental perception, and organizational adaptation strategy emerged from …

Optimization And Resistance Mitigation Of Dicamba And Glufosinate In Xtendflex® Crops, Grant Lawson Priess

Graduate Theses and Dissertations

The commercial launch of XtendFlex® crops enabled the use of dicamba, glufosinate, and glyphosate in-season. Utilizing herbicides that target different sites of action within troublesome weeds has been a tactic proposed to mitigate the likelihood of target-site resistance evolving; however, if interactions of the herbicides are detrimental to control of weedy species the likelihood of metabolic resistance increases. The objective of this research was to: 1) optimize efficacy and economic benefits of dicamba, glufosinate, and glyphosate; 2) characterize any interactions that were observed; 3) understand the mechanisms responsible for the reductions in weed control; 4) attempt to overcome interactions that …

The Morphodynamic Interaction Of River Deltas And Their Marshes, Kelly M. Sanks

Graduate Theses and Dissertations

Globally, many of the largest river deltas contain vast marsh platforms that are currently threatened due to a combination of anthropogenic alterations to rivers and increasing relative sea level rise. Restoration and management plans for river deltas depend on optimizing riverine sediment accumulation in marsh platforms. However, the accumulation of organic material in marsh platforms is often neglected in predictive models and the interaction of ecogeomorphic processes governing marsh accumulation with the physical processes governing river delta growth is poorly understood.

Herein, I investigate this complex relationship through a combination of field and experimental studies. I show that in coastal …

Analysis Of Bacteriorhodopsin Suspended In A Bilayer Lipid Membrane, Moath Alhejji

Graduate Theses and Dissertations

The bacteriorhodopsin protein’s unique characteristic of proton pumping can convert light energy to electric energy. The aim of this research was to generate photocurrent using bacteriorhodopsin in a bi-layer lipid membrane. Lipid monolayer and bilayer were formed using painting and folding methods, respectively. Capacitance and resistance of the lipid membranes were measured and used to validate the best methodology. My results show that the folding method is more efficient in incorporating Bacteriorhodopsin. The photocurrent was generated by illuminating a green laser (532 nm) on the bilayer lipid membranes. The patch clamp electrophysiology technique was used to apply voltage across the …

Automated Flight Controller Adaptive Compensation For Actuator Failures In Transport Type Aircraft, Daniel James Fresella

Graduate Theses and Dissertations

Aircraft operate over a wide range of conditions including atmospheric, weight, and center ofgravity changes. This presents a substantial challenge to automatic control system designers. When these operating conditions are merged with a partial or full control surface failure, automatic flight control is near impossible with conventional controllers. Additionally, when pilots experience control failure emergencies during flight, workload and fatigue increase drastically. The continued research of automatic flight control systems that can seamlessly adapt to unmodelled failures will enable a new generation of robust aircraft control. In this paper a 9th order 6 degree of freedom aircraft model is used …

Fair And Diverse Group Formation Based On Multidimensional Features, Mohammed Saad A Alqahtani

Graduate Theses and Dissertations

The goal of group formation is to build a team to accomplish a specific task. Algorithms are being developed to improve the team's effectiveness so formed and the efficiency of the group selection process. However, there is concern that team formation algorithms could be biased against minorities due to the algorithms themselves or the data on which they are trained. Hence, it is essential to build fair team formation systems that incorporate demographic information into the process of building the group. Although there has been extensive work on modeling individuals’ expertise for expert recommendation and/or team formation, there has been …

Design, Extraction, And Optimization Tool Flows And Methodologies For Homogeneous And Heterogeneous Multi-Chip 2.5d Systems, Md Arafat Kabir

Graduate Theses and Dissertations

Chip and packaging industries are making significant progress in 2.5D design as a result of increasing popularity of their application. In advanced high-density 2.5D packages, package redistribution layers become similar to chip Back-End-of-Line routing layers, and the gap between them scales down with pin density improvement. Chiplet-package interactions become significant and severely affect system performance and reliability. Moreover, 2.5D integration offers opportunities to apply novel design techniques. The traditional die-by-die design approach neither carefully considers these interactions nor fully exploits the cross-boundary design opportunities.

This thesis presents chiplet-package cross-boundary design, extraction, analysis, and optimization tool flows and methodologies for high-density …

Catalytic Activity Of Molybdenum-Dioxo Complexes, Randy Tran

Graduate Theses and Dissertations

This dissertation details the development of rationally designed dioxomolybdenum catalyst active for deoxydehydration (DODH), the net reduction of diols and polyols into alkenes and dienes. Catalyst design involved variations on dioxomolybdenum(VI) supported by a dianionic meridional pincer ligand. Rational substrate scope was explored using aliphatic diols, aromatic diols, and biomass derived diols. Various reductants were tested for ability to catalyze the reaction. The substrate specific mechanism of DODH was explored utilizing NMR and in-situ infrared spectroscopy and important rate constants and rate determining steps were found to aid in the optimization of ideal reaction conditions. Catalytic activity was observed to …