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Articles 1501 - 1530 of 3321
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Relationship Among Genetic And Physiological Biomarkers, And Horse Characteristics, Casey Orr
Relationship Among Genetic And Physiological Biomarkers, And Horse Characteristics, Casey Orr
Graduate Theses and Dissertations
The objective of this study was to evaluate relationships among genetic and physiological biomarkers and phenotypic characteristics in horses. Three breeds (Quarter Horse, Thoroughbreds, Miniatures), and five genes of interest (leptin, ghrelin, cytochrome P450, glucocorticoid receptor, and lactate dehydrogenase) were the basis of the investigation. Genomic DNA was extracted from buffy coat samples of Quarter Horses (n = 21), Thoroughbreds (n = 26), and Miniatures (n = 34). Data were analyzed using MIXED MODEL procedures of SAS, with the main effects of breed and SNP genotype. Horse was the experimental unit, and dependent variables were classified as physical, cell differentials, …
Influence Of Ph And Acidic Side Chain Charges On The Behavior Of Designed Model Peptides In Lipid Bilayer Membranes, Venkatesan Rajagopalan
Influence Of Ph And Acidic Side Chain Charges On The Behavior Of Designed Model Peptides In Lipid Bilayer Membranes, Venkatesan Rajagopalan
Graduate Theses and Dissertations
The molecular properties of transmembrane proteins and their interactions with lipids regulate biological function. Of particular interest are interfacial aromatic residues and charged residues in the core helix whose functions range from stabilizing the native structure to regulating ion channels. This dissertation addresses the pH dependence and influence of potentially negatively charged tyrosine, glutamic acid or aspartic acid side chains. We have employed GWALP23 (acetyl-GGALW5LALALALALALALW19LAGA-amide) as favorable host peptide framework. We have substituted W5 with Tyr (Y5GWALP23) and Leu residues with Glu (L12E, L14E or L16E) or Asp (L14D or L16D), and have incorporated specific 2H-labeled alanine residues within the …
Scaffold And Tissue Based Therapies To Improve Skeletal Muscle Regeneration After Volumetric Muscle Loss, Benjamin Kasukonis
Scaffold And Tissue Based Therapies To Improve Skeletal Muscle Regeneration After Volumetric Muscle Loss, Benjamin Kasukonis
Graduate Theses and Dissertations
Volumetric muscle loss (VML) is an injury to skeletal muscle characterized by a loss of more than 20% of a muscles volume. The combination of the bulk loss of tissue, transection and separation of myofibers proximal and distal to the injury, loss of innervation and blood supply, and the depletion of muscle progenitor cells results in permanent fibrosis and functional deficits due to loss of contractile tissue. Scaffolds, cells, and engineered constructs have been explored as potential therapeutic interventions to induce myogenesis at the site of a VML injury in animal models, in addition to limited clinical trials. This dissertation …
Ecological Approaches To Modernism, The U.S. South, And 20th Century American Literature, Justin Ford Tinsley
Ecological Approaches To Modernism, The U.S. South, And 20th Century American Literature, Justin Ford Tinsley
Graduate Theses and Dissertations
This project seeks to draw from the insights of the emerging scholarly discipline known as ecocritism, study of the relationship between human and nonhuman in all arts and in all diverse forms, and apply them to the study of a specific regional art, that of the U.S. South. As an interrogation of the human / nonhuman binary, ecocriticism is intrinsically intertwined with the concept of place. Southern studies—having long explored the diversity (in terms of both human experience and geographical terrain) characterizing the region—offers ecocriticism a ripe testing ground for theoretical mergers and analytic applications. Both fields celebrate hybridity, multiplicity, …
How Select Groups Of Preservice Science Teachers With Inquiry Orientations View Teaching And Learning Science Through Inquiry, Peggy Diana Ward
How Select Groups Of Preservice Science Teachers With Inquiry Orientations View Teaching And Learning Science Through Inquiry, Peggy Diana Ward
Graduate Theses and Dissertations
Although hailed as a powerful form of instruction, in most teaching and learning contexts, inquiry-based instruction is fraught with ambiguous and conflicting definitions and descriptions. Yet little has been written about the experiences preservice science teacher have regarding their learning to teach science through inquiry. This project sought to understand how select preservice secondary science teachers enrolled in three UTeach programs in Arkansas conceptualize inquiry instruction and how they rationalize its value in a teaching and learning context. The three teacher education programs investigated in this study are adoption sites aligned with the UTeach Program in Austin, TX that distinguishes …
Bioorthogonal Reactions: Synthesis And Evaluation Of Different Ligands In Copper Catalyzed Azide-Alkyne1,3-Dipolar Cycloaddition (Cuaac), Zainab Abdullah Almansaf
Bioorthogonal Reactions: Synthesis And Evaluation Of Different Ligands In Copper Catalyzed Azide-Alkyne1,3-Dipolar Cycloaddition (Cuaac), Zainab Abdullah Almansaf
Graduate Theses and Dissertations
The Copper CatalyzedAzide-Alkyne1,3-Dipolar Cycloaddition (CuAAC) reaction has unique features that qualify it to be one of the best click reactions. Its applications have been shown in different aspects and for multiple purposes. The oxidative degradation of biological systems (labile proteins and live cells) is, however, generally recognized as the major problem when using this reaction in living systems. Reactive oxidation species can be easily produced in the presence of copper(II), ascorbate and air, and this is the main cause of toxicity. However, the uses of ligands have shown a major impact on reducing copper toxicity, protecting Cu(I) from the redox …
Liming Characteristics Of A High-Calcium, Dry Flue Gas Desulfurization By-Product And Its Effects On Runoff Water Quality, Jason Richard Burgess-Conforti
Liming Characteristics Of A High-Calcium, Dry Flue Gas Desulfurization By-Product And Its Effects On Runoff Water Quality, Jason Richard Burgess-Conforti
Graduate Theses and Dissertations
In 2013, only 37% of the 32 million Mg of flue gas desulfurization (FGD) by-products generated in the United States were reused beneficially. If FGD by-products could be used as a beneficial soil amendment, millions of megagrams may be diverted away from surface impoundments and landfills. The purpose of this research was to identify the liming characteristics of a high-Ca dry FGD (DFGD) by-product in comparison to a Class-C fly ash (FA) and reagent-grade CaCO3, and to evaluate the effects of land application to a managed grassland on runoff, plant, and soil quality. Liming characteristics were determined by measuring the …
Eveleth, Minnesota: A Portrait Of My Home Town, Judith I. Luna
Eveleth, Minnesota: A Portrait Of My Home Town, Judith I. Luna
Graduate Theses and Dissertations
This 30-minute documentary film provides snapshots of the small northeastern iron mining town of Eveleth, Minnesota, on the Mesabi Iron Range. It uses a two-pronged approach: 1) a first-person return to the town by the filmmaker almost 50 years after graduating from high school to see how the town may have changed, 2) a look at some historical and cultural factors which made the town what it was when the filmmaker was growing up and what continues to animate the town in the face of iron mining’s decline and rebirth. The latter include the immigrant experience and influence as the …
The Role Of Organic Matter In The Fate And Transport Of Antibiotic Resistance, Metals, And Nutrients In The Karst Of Northwest Arkansas, Victor Lee Roland Ii
The Role Of Organic Matter In The Fate And Transport Of Antibiotic Resistance, Metals, And Nutrients In The Karst Of Northwest Arkansas, Victor Lee Roland Ii
Graduate Theses and Dissertations
Organic matter (OM) in the environment acts as a nutrient, but may also act as a transport vector for harmful chemical compounds and bacteria. Acetate is a labile form of OM produced during fermentation in anaerobic lagoons used to store animal fecal-waste from concentrated animal feeding operations (CAFOs). Dry and liquid fertilizers from CAFOs pose a threat to groundwater by introducing excessive amounts of nutrients (e.g. OM, nitrate and ammonia), metals, and antibiotic compounds. In the epikarst of Northern Arkansas in the Buffalo River watershed additional input of labile dissolved organic carbon (DOC) from liquid CAFO waste-fertilizers was hypothesized to …
Optical Water Quality And Human Perceptions Of Rivers, Amie West
Optical Water Quality And Human Perceptions Of Rivers, Amie West
Graduate Theses and Dissertations
Understanding water quality dynamics in recreational rivers is integral in shaping management strategies that maintain ecosystem health, perceived value and appeal, and regional economic significance in a changing environment. Optical water quality describes the behavior of light in water as governed by its physical and chemical composition, and is among the strongest influences on human perceptions of water quality. Ethnohydrology is the study of culturally constructed knowledge and understanding of water. This work is the culmination of an interdisciplinary approach to water resources research—integrating optical water quality and ethnohydrology methods to recognize the intersection between measured water quality and visible …
Agro-Climatic Change, Crop Production And Mitigation Strategies-Case Studies In Arkansas, Usa And Kenya, John Westley Magugu
Agro-Climatic Change, Crop Production And Mitigation Strategies-Case Studies In Arkansas, Usa And Kenya, John Westley Magugu
Graduate Theses and Dissertations
Although climate change impacts vary geographically and temporally, studies at local levels are not readily available for stakeholders to better understand how their local communities would be affected and what remedial measures could be more effective in their local contexts. This dissertation has examined climate change and its impacts in two different local contexts: eastern Arkansas in the USA and Nyando in Kenya. The first part of this dissertation develops agro-meteorological indicators and examines the relationship between agro-meteorological indicators and crop yields in eastern Arkansas between 1960 and 2014. Results reveal that temperature based indicators were more strongly correlated to …
Eucalyptus In Kenya; Impacts On Environment And Society, Brandy M. Garrett Kluthe
Eucalyptus In Kenya; Impacts On Environment And Society, Brandy M. Garrett Kluthe
Graduate Theses and Dissertations
Eucalyptus trees were introduced to Kenya a little over a century ago. European colonization along with the development of a railway system increased the demand for a fast growing wood source. The expansion of the tree across the fertile lands in Kenya raises concerns about the environmental impact on ecosystems where it has been introduced. These concerns include degraded soils, loss of water resources, co-introduction of ectomycorrhizal species, and allelopathy. Economic benefits to local landowners were also explored as well as the potential for large Eucalyptus woodlots to maximize the sequestration of CO₂ from the atmosphere. This was examined through …
Essays On Optimization And Modeling Methods For Reliability And Reliability Growth, Thomas Paul Talafuse
Essays On Optimization And Modeling Methods For Reliability And Reliability Growth, Thomas Paul Talafuse
Graduate Theses and Dissertations
This research proposes novel solution techniques in the realm of reliability and reliability growth. We first consider a redundancy allocation problem to design a system that maximizes the reliability of a complex series-parallel system comprised of components with deterministic reliability. We propose a new meta-heuristic, inspired by the behavior of bats hunting prey, to find component allocation and redundancy levels that provide optimal or near-optimal system reliability levels. Each component alternative has an associated cost and weight and the system is constrained by cost and weight factors. We allow for component mixing within a subsystem, with a pre-defined maximum level …
Investigation Of Cnt-Induced Escherichia Coli Lysis And Protein Release, Abdollah Mosleh
Investigation Of Cnt-Induced Escherichia Coli Lysis And Protein Release, Abdollah Mosleh
Graduate Theses and Dissertations
This research investigated the use of carbon nanotubes (CNTs) as a treatment to increase the permeability of a bacterial cell wall. Recombinant Escherichia coli BL21 (DE3) containing a plasmid that expressed Green Fluorescent Protein (GFP) and -lactamase were exposed to CNTs under various levels of agitation for different times. Fluorescence assay for GFP, optical absorbance for -lactamase activity, and Transmission Electron Microscopy (TEM) were used to determine the amount of released protein, and visually examine the permeability enhancement of the cells, respectively. It was found that more -lactamase was present in the culture fluid after treatment with CNTs in a …
Comparisons Of Selected Household And Commercial Disinfectants Against Poultry Salmonella Isolates And A Survey Of Internal Parasites In Backyard Poultry In Arkansas, Kayleigh Moyle
Graduate Theses and Dissertations
Backyard and exhibition poultry have been gaining in popularity and as such there has been a large increase in the number of small flocks. As the interaction with poultry has increased, so has the opportunity for diseases and parasites, for both birds and people. One of the major zoonotic illnesses is caused by the bacteria Salmonella, which can be found in commercial and small flocks. Salmonella is the number 2 contributor of foodborne illnesses so its prevalence in commercial flocks is of high concern. Despite improved cleaning, disinfection, and biosecurity practices, there is still potential for disease outbreaks and infections …
Microbes In Rough Rice – Prevalence, Growth Kinetics And Links To Dry Matter Loss, Supriya Thote
Microbes In Rough Rice – Prevalence, Growth Kinetics And Links To Dry Matter Loss, Supriya Thote
Graduate Theses and Dissertations
The prevalence of microorganisms on freshly-harvested long-grain hybrid, long-grain pureline, and medium-grain rice has not been elucidated. The first objective of this two-part study was to determine the relative prevalence of microbes on freshly-harvested, high moisture content rice of different types and cultivars. The total and surface aerobic plate counts (APC) and mold counts were determined in terms of log10 colony forming units per gram of rice (log10 CFU/g) for six rice cultivars over two years. In 2013, among harvested samples of all the studied rice cultivars, the long-grain hybrid cultivars had the lowest APC levels (M = 8.10, SD …
The Cytotoxic And Antimicrobial Properties Of Pine Essential Oils: A Characterization And Comparison, Richard Sakul
The Cytotoxic And Antimicrobial Properties Of Pine Essential Oils: A Characterization And Comparison, Richard Sakul
Graduate Theses and Dissertations
In the forestry industry, the pine tree species are important because of their durable timber and fast growth. In Arkansas, trees such as the loblolly pine compose almost a third of the timberland, seven million acres. In addition to the lignocellulosic biomass, pine bark and needles potentially have industrial importance as a waste stream from which high value (e.g., pharmaceutical, cosmetics) chemicals could be extracted, which could potentially increase the profit margin of forestry operations. In this research, the possibility that pine needles harvested from industry processed pine tree residues could be used as an antibacterial or cytotoxic chemical agent …
The Impact Of Crop Insurance On Indonesian Rice Production, Zaura Fadhliani
The Impact Of Crop Insurance On Indonesian Rice Production, Zaura Fadhliani
Graduate Theses and Dissertations
This study builds a theoretical model of the yield-based MPCI crop insurance policy for a risk averse rice farmer in Indonesia and presents the comparative statics analysis of policy variables on yield through the coupling, wealth, and insurance effects. Moreover, Using yield data from 1979 to 2014 for the Tuban Regency, this study applies numerical optimization to the model and simulates the effects of different policies on input use, certainty equivalents, indemnity payment, and premiums. The theoretical analysis shows that no coupling effect exists for change in the coverage level, while a coupling effect exists for change in the subsidy …
Cross Validation Of The Caregiving Helplessness Questionnaire: Associations With Maternal History Of Maltreatment And Intimate Partner Violence, Maegan Calvert
Cross Validation Of The Caregiving Helplessness Questionnaire: Associations With Maternal History Of Maltreatment And Intimate Partner Violence, Maegan Calvert
Graduate Theses and Dissertations
Disorganized caregiving has been associated with both maternal childhood history and current experiences of trauma. However, the methods by which disorganized caregiving has been studied have been time intensive and costly. The current study aimed to extend previous research with the Caregiving Helplessness Questionnaire (CHQ; George & Solomon, 2011), which is a self-report measure designed to assess aspects of disorganized caregiving such as caregiving helplessness, role reversal, and frightened/frightening caregiving experiences. Participants (N = 156) were a community sample of mothers of children ages 5 to 10 who were primarily white and who reported a range of traumatic experiences. It …
Discretion And The Implementation Of Federal Disability Policy In Postsecondary Education, Katy Annette Washington
Discretion And The Implementation Of Federal Disability Policy In Postsecondary Education, Katy Annette Washington
Graduate Theses and Dissertations
Disability Services Providers (DSPs) have historically been the personnel tasked with implementing federal disability policy at postsecondary institutions primarily since the passage of Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Act in 1990. The model adopted by the majority of DSP offices is student-driven and requires students seeking academic accommodations must go through a formal process to determine eligibility for services, and then play an active role in their provision. Disability-related policies at the campus level are usually authored by DSPs who are seen as experts by the institution and its stakeholders. However, sometimes …
Listeria Monocytogenes Strain Variation: Starvation, Metabolism, And Macrophage Survival, Nathan A. Jarvis
Listeria Monocytogenes Strain Variation: Starvation, Metabolism, And Macrophage Survival, Nathan A. Jarvis
Graduate Theses and Dissertations
Listeria spp. are often isolated from raw and processed food products. Listeria monocytogenes is responsible for death rates of 10 to 30% in immune compromised people; it can also infect a vast range of animals. There are numerous reports of poultry harboring or becoming infected with L. monocytogenes. First, this research assessed the ability of L. monocytogenes to replicate within chicken macrophages. Using the gentamicin-killing assay, a cell culture of chicken macrophage-like cells (HD11) were infected with two strains of L. monocytogenes individually (EGD-e and Scott A). Results show that unlike data on mouse macrophages, intracellular L. monocytogenes do not …
Chlorine Demand Shows Thresholds And Hierarchy With Source Water Quality At Beaver Lake, Arkansas, Jaime M. Gile
Chlorine Demand Shows Thresholds And Hierarchy With Source Water Quality At Beaver Lake, Arkansas, Jaime M. Gile
Graduate Theses and Dissertations
This study investigated the effects of source water quality in Beaver Lake on the amount of chlorine (Cl) needed to develop decision support system to help guide chlorination practices in pre-treatment of source water. Chlorine demand assays were performed on water samples from Beaver Lake collected from the intake structure at Beaver Water District from March 2014 through August 2015, and using data from these assays, the two points of interest in this study were the Cl dose at which Cl residuals began to accumulate and the mean Cl demand occurring after that dose. Three methods of analysis were used …
Assessment Of The Level Of Protection Against Coccidiosis In Broiler Breeders Conferred By A Live Anticoccidial Vaccine, And Its Influence On Early Growth And Development., Muhammed Shameer Abdul Rasheed
Assessment Of The Level Of Protection Against Coccidiosis In Broiler Breeders Conferred By A Live Anticoccidial Vaccine, And Its Influence On Early Growth And Development., Muhammed Shameer Abdul Rasheed
Graduate Theses and Dissertations
Coccidiosis continues to be a great challenge to the poultry industry all over the world and in broiler breeders vaccination with live oocysts of Eimeria has been widely adopted as a control measure. Broiler breeders are usually subjected to feed restriction during their early growth however no studies have been undertaken on the effects of vaccination in birds whose feed has been restricted in this manner. The objective of this study was to assess the level of protection acquired by broiler breeder chickens when immunized at day-old with live eimerian oocysts and given a restricted diet. Effects upon growth and …
Heparin-Peptide Interactions, Jacqueline Anastasia Morris
Heparin-Peptide Interactions, Jacqueline Anastasia Morris
Graduate Theses and Dissertations
Heparin is a polydispersed sulfated molecule that is part of the family called glycosaminoglycans found in the extracellular matrix and cell surfaces. This molecule is extremely important for the activation of proteins and protein-receptor interactions that are responsible for downstream cell signaling pathways. Heparin has been isolated from porcine intestine and used as an anticoagulant for the prevention of embolisms, heart thrombosis, and clotting during heart surgeries. This so-called miracle drug was in use until 2008, when isolated batches were found to be contaminated with other glycosaminoglycans similar to heparin. From 2008, there has been a dire need for a …
Elucidating The Genetic Cause To Ascites Syndrome In Broiler Chickens Utilizing Multi-Generational Genome Wide Association Studies, Katy Tarrant
Graduate Theses and Dissertations
Ascites syndrome in broiler chickens has developed into a source of economic loss in the last three decades. Intensive selective pressure, and implementation of flock management practices, has successfully reduced ascites frequency, but has not eliminated its occurrence. For this reason, it is imperative to better understand the genetic cause to ascites in broiler chickens. Previous studies of this magnitude have been attempted, but, thus far, a consensus of genomic associations have not been made. This collection of studies was aimed at identifying and interpreting genomic and genetic associations to ascites phenotype specific to a broiler line representative of a …
Proposed Treatment Of Problematic Pornography Use: A Cognitive-Behavioral Approach, Jennifer Minarcik
Proposed Treatment Of Problematic Pornography Use: A Cognitive-Behavioral Approach, Jennifer Minarcik
Graduate Theses and Dissertations
As pornography use increases across the general population, mental health professionals are encountering more patients who present symptoms of sexual addictions and sexual compulsivity (Cooper et al., 2001). Never before have pornographic materials been so accessible to consumers. Viewing pornography is related to many negative consequences for the individual, including impairment of academic and professional functioning, subjective distress, and sexual compulsivity (Cooper et al., 1999a; Manning, 2006). Studies found pornography use by an individual typically leads to a decline in relationship and sexual satisfaction (Bridges, 2008a). Despite the growth in research related to problematic pornography use, to date there have …
Studies In The Asymmetric Synthesis Of The C21-C34 Fragment Of The Natural Product, Antascomicin B, Brian Lee Walker
Studies In The Asymmetric Synthesis Of The C21-C34 Fragment Of The Natural Product, Antascomicin B, Brian Lee Walker
Graduate Theses and Dissertations
This dissertation describes studies in the asymmetric synthesis of the C21 – C34 fragment of the natural product, antascomicin B. Antascomicin B is structurally related to FK506, binds strongly to FKBP12, yet does not shown immunosuppressive activity. Small ligand FKBP12 binding complexes were shown to have potent neuroprotective and neuroregenerative properties in mouse models of Parkinson’s disease. The highlighted chemical reactions include an asymmetric transfer hydrogenation (ATH), Ireland-Claisen rearrangement (ICR), directed hydrogenation and allylic diazene rearrangement.
Trend Analysis Of Water Quality In Northwest Arkansas Streams Reflects Changes In The Watershed, Zachary Paul Simpson
Trend Analysis Of Water Quality In Northwest Arkansas Streams Reflects Changes In The Watershed, Zachary Paul Simpson
Graduate Theses and Dissertations
Watershed export of nutrients, sediments, and chemicals impacts receiving waters. Changes within the watershed (e.g., anthropogenic or climatic) can alter the transport of constituents in streams. Stream monitoring is crucial for understanding these effects. This study developed a potential improvement to flow-adjusting constituent concentrations in streams, an important step of analyzing monitoring data in lotic systems for trends. The method incorporates a K-fold cross-validation procedure to optimize a model explaining the relationship between the concentration and streamflow, thus providing a valuable tool to researchers in water quality. Additionally, two case studies were conducted on watersheds located in northwest Arkansas using …
An Investigation Of Short-Term Plasticity In Human Motor Cortex, Matthew Alan Gannon
An Investigation Of Short-Term Plasticity In Human Motor Cortex, Matthew Alan Gannon
Graduate Theses and Dissertations
Transcranial magnetic stimulation (TMS) produces a transient magnetic field that activates underlying cortical tissue by eliciting an electrical discharge of the neurons in the targeted area. Repetitive TMS (rTMS) uses patterns of repetitive TMS pulses and has been reliably shown to produce changes in the state of cortical excitability outlasting the time of stimulation. One such protocol that has demonstrated states of increased excitability is intermittent theta burst stimulation (iTBS). This method applies high-frequency bursts (50Hz) of pulses every 200 ms in trains of ten bursts. The effects of and differences between rTMS protocols have been investigated since gaining popularity …
Beer For Brohood: A Laboratory Simulation Of Masculinity Confirmation Through Alcohol Use Behaviors In Men, Jessica Lauren Fugitt
Beer For Brohood: A Laboratory Simulation Of Masculinity Confirmation Through Alcohol Use Behaviors In Men, Jessica Lauren Fugitt
Graduate Theses and Dissertations
Alcohol use is a widespread behavior that may be associated with negative consequences, especially for men. Research suggests that individuals are motivated to maintain in-group status by engaging in behaviors prototypical of the in-group when group status has been challenged, and that men are particularly likely to do this when masculine in-group status is threatened. This study investigated masculine drinking behaviors through Social and individual lenses, examining the impact of group identification and individual differences on alcohol consumption rates after a simulated gender threatening situation in a bar laboratory. Sixty-five male students (ages 21-29; 74% Caucasian) were given the chance …