Digital Commons Network^™

Floating-Gate Design And Linearization For Reconfigurable Analog Signal Processing, Steven Michael Andryzcik Ii

Graduate Theses, Dissertations, and Problem Reports (ETD)

Analog and mixed-signal integrated circuits have found a place in modern electronics design as a viable alternative to digital pre-processing. With metrics that boast high accuracy and low power consumption, analog pre-processing has opened the door to low-power state-monitoring systems when it is utilized in place of a power-hungry digital signal-processing stage. However, the complicated design process required by analog and mixed-signal systems has been a barrier to broader applications. The implementation of floating-gate transistors has begun to pave the way for a more reasonable approach to analog design. Floating-gate technology has widespread use in the digital domain. Analog and …

Association Of Incident Cancer To Low-Value Care And Healthcare Cost Burden Among Elderly Medicare Beneficiaries, Chibuzo Iloabuchi

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the United States (US), 25% of healthcare spending is considered wasteful because it is spent reimbursing low-value care. Low-value care is the utilization of healthcare services, medical tests, and procedures that have unclear or no clinical benefit to patients but still exposes them to risk. World-wide, low-value care imposes a significant economic burden on patients, payers, governments, and society. Cancer care among older adults > 65 years is one of the biggest drivers of healthcare expenditure in the US and accounts for nearly 40% of all spending, and low-value care among cancer patients is prevalent and contributes to the financial …

Reframing: A Grounded Theory Study Of Postmenopausal Women Following Osteoporotic Fracture, Ashley D. Barber

Graduate Theses, Dissertations, and Problem Reports (ETD)

BACKGROUND: Osteoporosis is a chronic disease resulting in low bone mass and increased bone fragility. Most often seen in women age 65 and older, osteoporosis is usually diagnosed following osteoporotic fracture. Despite numerous treatment options many women continue to remain untreated for osteoporosis and are at increased risk for subsequent fractures and complications. PURPOSE: The initial purpose of this classic grounded theory study was to explore the decision-making process women aged 65 and older experience when considering osteoporosis treatment following osteoporotic fracture. Following the tenth participant interview the researcher discovered a new main concern that emerged from participant interviews. Participants …

Understanding The Variable Drivers Of Toxicity For The Broad Class Of Carbon Nanotubes And Nanofibers From U.S. Facilities, Kelly E. Fraser

Graduate Theses, Dissertations, and Problem Reports (ETD)

Pulmonary exposure to carbon nanotubes or nanofibers (CNT/F) is known to induce inflammation, toxicity, or tumorigenesis, and is a concern in the occupational setting. U. S. facility employees are at risk of inhalation exposure of multi-walled carbon nanotubes and carbon nanofibers during primary and secondary manufacturing. To date, only one MWCNT, Mitsui-7 has been classified as possibly carcinogenic to humans (Group 2B), while all other materials were subsequently categorized as unclassifiable (Group 3). This class of material has recently been listed as a high priority to the International Agency for Research on Cancer due to this significant knowledge gap. Furthermore, …

Comparing Spanish L2 Use Of Regional Phonemes After Study Abroad In Spain And Mexico, Katherine R. Lindley

Graduate Theses, Dissertations, and Problem Reports (ETD)

The present study analyzed the use of regional phonemes by native-English speakers before and after spending a year abroad in either Spain or Mexico. The variables selected were the interdental voiceless fricative [θ] and the uvular voiceless fricative [χ], along with their variations. Semi-structured oral interviews were used to elicit data before their sojourn and at the end of their stay. Results show that many participants used [θ] and [χ] more after spending a year in Spain and participants preferred [s] and [h] after spending a year in Mexico. Data on social networks were collected throughout the study for the …

Variations In Produced Water Chemistry And Relation To Regional Geology And Production In The Marcellus Shale, Northcentral West Virginia, Jonathan M. Brady

Graduate Theses, Dissertations, and Problem Reports (ETD)

An investigation of 74 Marcellus Shale wells across northcentral West Virginia indicates changes in produced water chemistry and quantity can be related to geologic conditions based on well logs and core data. These changes are determined by reviewing multiple produced water analyses for individual wells for periods up to ten years. Results show variations among the areas in this study. From west to east across central Harrison County to central Taylor County, then north into Monongalia County, gamma-ray logs show increasing intensity, especially in the middle and lower Marcellus. XRD mineralogy from core data shows increasing clay content from west …

Doctors, Miners, And Black Lung: A Transatlantic Comparison Of Organized Medicine's Role In The Fight For Black Lung Recognition In West Virginia And Wales, Mollie M. Cecil Md

Graduate Theses, Dissertations, and Problem Reports (ETD)

Black lung disease is a crippling occupational lung disease experienced by coal miners throughout the world. However, this disease was not always recognized by the medical profession and required significant efforts on the part of miners’ unions to force mainstream recognition. The historiography on the subject is limited, especially with respect to the relationship between organized medicine and organized labor. This work further explores this relationship, particularly how this relationship differed between the parties in Wales and in West Virginia. In doing so, it portrays a more detailed picture of the fight for black lung recognition as well as highlights …

Initial And Advanced Stages Of Microbiota Establishment Within The Tsetse Fly, Miguel Eduardo Medina Munoz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Symbiosis is a long-term physical association between two or more species, although little is known regarding its evolutionary origins, particularly at the genetic level. Tsetse flies are the vector of African trypanosomes, causative agents of Human and Animal African Trypanosomiases. Tsetse provide an ideal model for studying initial and advanced stages of symbiosis. Tsetse have a simple digestive tract microbiota primarily consisting of two bacteria; the ancient mutualist Wigglesworthia glossinidia and the recently acquired Sodalis glossinidius. This work presents a chronological study in evolutionary terms of the history of a microbial-insect association. First, I present concepts on symbiosis and …

Bravery In The Delicate: An Actor's Exploration Of Thea Elvsted In Henrik Ibsen's Hedda Gabler, Mary Catherine Goff

Graduate Theses, Dissertations, and Problem Reports (ETD)

This purpose of this document is twofold: to examine the process of character creation over the course of my experiences performing the role of Thea Elvsted in West Virginia University’s spring 2020 production of Henrik Ibsen’s Hedda Gabler, and to define Thea’s dramatic significance to Hedda Gabler as a whole. The following text will provide a detailed look at the research I collected in the interest of building a cohesive view of the world of the play. Additionally, it will describe the various techniques I employed throughout the rehearsal and performance process of the production, with specific attention paid to …

From Inner Segment To Outer Segment: Palmitoylation Of Photoreceptor Na+, K+-Atpase And The Importance Of Prcd In Photoreceptor Outer Segment Morphogenesis, Emily R. Sechrest

Graduate Theses, Dissertations, and Problem Reports (ETD)

Photoreceptors are specialized neuroepithelial cells which are optimized for efficient capture of light and initiation of visual transduction. These cells have several compartments which are very important for proper visual function and segregation of cellular processes, including the outer segment (OS), inner segment (IS), nucleus, and synapse. The IS houses all of the cellular organelles and biosynthetic molecular machinery the cell requires and is the site of protein synthesis. The light-sensing OS is a highly modified, primary cilium, which contains many stacks of double membranous discs which house proteins required for formation and maintenance of OS structure, as well as …

Dynamic Optimization Algorithms For Baseload Power Plant Cycling Under Variable Renewable Energy, Rebecca Hyen Hae Kim

Graduate Theses, Dissertations, and Problem Reports (ETD)

The growing deployment of variable renewable energy (VRE) sources, such as wind and solar, is mainly due to the decline in the cost of renewable technologies and the increase of societal and cultural pressures. Solar and wind power generation are also known to have zero marginal costs and fuel emissions during dispatch. Thereby, the VRE from these sources should be prioritized when available. However, the rapid deployment of VRE has heightened concerns regarding the challenges in the integration between fossil-fueled and renewable energy systems. The high variability introduced by the VRE as well as the limited alignment between demand and …

Innovations In Money And Banking Markets, Eduardo Guimaraes Minuci

Graduate Theses, Dissertations, and Problem Reports (ETD)

The U.S. banking industry has experienced several technological and banking regulatory changes in the past two decades. This dissertation is composed of three papers that review and investigate how these banking and technological innovations have impacted depositors, bank provision of monetary assets, and bank performance. The order in which the papers are presented follows the order in which they were produced as the production of one paper helped spark ideas that led to the next.

Motivated by the fact that money has become more heterogeneous in terms of its returns, Chapter 1 focus on innovations in money markets by focusing …

Three Essays In Regional Economics, Zachary Keeler

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation consists of three essays that use applied econometric analysis and other analytical methods from various economic fields, including regional and urban economics, natural resource economics, housing economics, and sports economics. In all three essays, I use housing data to value various amenities and disamenities. Using several variations on the hedonic method, I am able to uncover the values based on the capitalization effect. I consider the effect of natural resource development by examining shale gas development, as well as the effect of urban development projects, including public transportation and sports facilities.

In the first essay of my dissertation, …

[K], [G] And [ʔ] In Amman: Social Associations And Identity Perception In Young Rural [Fallahin] Palestinian Speech, Shahd Abu Nahel

Graduate Theses, Dissertations, and Problem Reports (ETD)

Built after several immigration waves, Amman developed its own dialect. Previous studies investigated the stylistic and social reallocation process (Britain & Trudgill, 2005) that happened to some major phonemes. The three phonemes [k], [ʔ] and [g] are dialectal reflexes of the Arabic modern standard uvular phoneme [q], and they correlate with social aspects like gender, identity and social class. This study has two parts the first investigates the distribution of the phonemes of the first generation of rural Palestinians hypothesizing that they will follow the generalizations found in Al-Wer (2011). The second part is a large-scale questionnaire targeting the social …

Pseudomonas Aeruginosa Vaccine Development Using Dual-Species Whole Cell And Subunit Vaccines, Catherine Bell Blackwood

Graduate Theses, Dissertations, and Problem Reports (ETD)

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen which can cause severe, recurrent, and chronic infections. The pathogen is highly adaptable, and pneumonia caused by it is associated with high morbidity and mortality, especially in individuals with the genetic disorder cystic fibrosis. Antibiotic resistance amongst clinical isolates of P. aeruginosa is steadily increasing, and multi-drug resistant strains are prevalent. There is currently no vaccine available for commercial use against P. aeruginosa. For these reasons, we sought to understand the immunity to P. aeruginosa induced by whole cell vaccination and identify antigens for development of future subunit vaccines. In this dissertation, …

Perceptions Of Integrated Mental And Behavioral Health In Pediatric Specialty Care Settings: A Mixed-Methods Study, Desireé Nicole Williford

Graduate Theses, Dissertations, and Problem Reports (ETD)

Pediatric patients are at an increased risk of experiencing mental and behavioral health concerns, which have direct associations with HRQOL, physiological health, and likelihood that youth will engage in health promoting behavior. Researchers and practitioners have increased their awareness of these concerns and identified strategies for improving the mental and behavioral health of these youth, specifically via implementing organizational efforts (i.e., task forces) and guidelines around integrating psychosocial screening and other services into routine practice. Despite this, there are several identified barriers to families receiving mental/behavioral health care in these settings. These barriers exist at all levels, including at the …

The Development And Distinction Of Emerging School Professionals: Boundary Work Of Guidance Counselors And School Psychologists, Madison E. Wilson

Graduate Theses, Dissertations, and Problem Reports (ETD)

As a compulsory part of our society, schools are a prominent institution in the United States and abroad. In a system with multiple domains of specialized professionals, it is important to define their roles, determine where there is overlap, and assess if both professions are functioning to best assist students. This study examines the boundary work and professionalization of two emerging mental health professions within the school system: guidance counselors and school psychologists. Thematic analysis of the boundary work in the editorials of each professions’ flagship journal show that much of the boundary work between the journals is similar and …

A Translational Analysis Of Renewal Following Dro With Human Subjects, Kacey R. Finch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Renewal is a type of behavioral relapse that is dependent on changes in contextual stimuli in the environment. The current study investigated ABA renewal of responding that had been previously reduced by a differential reinforcement of other behavior (DRO) procedure. ABA renewal refers to the context associated with three phases of behavioral treatment; Context A is present during baseline, Context B is present during treatment, and the post-treatment context returns to Context A (i.e., renewal test). Undergraduate college students participated in a Zoom video call during which they responded by clicking the mouse on a rectangle in a computer program …

Enabling Technologies For Medicinal Chemistry And Synthesis: I. Cannabinoids; Ii. Illudalic Acid; Iii. Microwave Chemistry, Harvey Fulo

Graduate Theses, Dissertations, and Problem Reports (ETD)

Innovations in synthetic organic chemistry such as methodology improvements, new chemical transformations and technology development significantly impact medicinal chemistry and continue to drive the drug discovery process. Here, new cyclization strategies to the pharmaceutically underexplored 3,3-dimethylcyclopentane-fused aromatic rings are described. One approach highlighted oxidative cycloisomerization, intermolecular [2+2+2] cyclotrimerization and 5-exo-dig cyclization providing indanoylindole cannabinoids that possess high affinity for human CB₂ receptors at nanomolar concentration and good selectivity index. Another featured a [4+2]-type benzannulation reaction which enabled the 5-step synthesis of illudalic acid — compared to the current available sequences (≥16 steps) — and its equipotent and LAR-selective analogs. …

Gendered Use Of Language In Facebook Status Updates Among Jordanian And American Youths: A Sociopragmatic Study, Ashraf Wenas Al Sad

Graduate Theses, Dissertations, and Problem Reports (ETD)

The study examines the types of speech acts of Facebook status updates that are posted by Jordanian and American youth. The participants were from Yarmouk University which is located in northern Jordan and from West Virginia University which is located in the US. The data was elicited from 50 American males, 50 American females, 50 Jordanian males, and 50 Jordanian females. Searle’s taxonomy was used to do the content analysis of the data. Searle’s taxonomy and additional speech acts were found: directive, expressive, assertive, God’s invocation, humor, and quotation. The findings of the study indicate that the religious and cultural …

Examining Changes In Learning And Engagement Of Higher Education Students In A Fully Online Flipped Learning Distance Education Classroom, James David Riel

Graduate Theses, Dissertations, and Problem Reports (ETD)

The challenge of implementing effective online distance education courses for academics and institutions is a centuries-old task. We can look across early developments in the 18^th century with the creation and delivery of correspondence courses; into the 20^th century with teaching and learning across analog methods such as audio and video; and now in the current era of digitized mechanisms that enable the online classroom. This includes advances in internet technologies and computing abilities that are the empowering the backbone processes, bridging connectivity between the student and the instructor. As society has trended toward massive increases in online …

An Examination Of The Start Now Dialectical Behavior Therapy-Based Intervention Plus A Behavioral Level System On Male Inmate Misbehavior, Aggressive Behavior, And Mental Health, Victoria Disciullo

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to evaluate the impact of the START NOW program + behavioral level system (BLS) in a self-contained therapeutic community (SCTC) on inmate misbehavior at a correctional facility in a southern state. The SCTC includes the START NOW manualized mental health treatment, recreation groups, process groups as needed, and additional positive reinforcement to target inmate prosocial behavior (i.e., level system to obtain privileges). Inmate data was evaluated at 3-months pre-START NOW intervention and 3-months post-START NOW intervention to determine if there were differences in the number of referrals to mental health services for misbehavior, write-ups …

The Role Of Tree Species, The Herb Layer, And Watershed Characteristics On Nitrogen Cycling In A Central Appalachian Hardwood Forest, Sian E. Eisenhut

Graduate Theses, Dissertations, and Problem Reports (ETD)

Little is known about the forest herbaceous layer’s contributions to nitrogen (N) cycling under varying levels of N deposition, at different stages of forest succession, in watersheds with different aspects, and under different tree species. The objectives of this study were to quantify nitrogen reductase activity (NRA) of two tree species, red maple and sugar maple, and surrounding common herb-layer species at the tissue (foliage, roots) and plot level and to assess how these species affect the concentrations of nitrate, ammonium, and organic N in soil water collected in lysimeters beneath these trees. Different watersheds located at the Fernow Experimental …

Imagined Communities: The British Planter In Nyasaland, 1890 - 1940, Benjamin Marnell

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis examines concepts of British settler identity and how it developed across trans-national bounds. Between the 19th and 20th centuries, the rise of industrialisation and developments in transportation, mass communication and print media fuelled a new wave of settler movements from Britain. As settlers spread to different continents, their identity as Britons was challenged in new ways. From this, a unique subgroup of settlers developed, known as planters. In this thesis, I examine the planter community that developed in the small South Central African country of Nyasaland, now Malawi. By examining Nyasaland’s settler community as a case study, I …

Updates And Improvements To The Satellite Drag Coefficient Response Surface Modeling Toolkit, Phillip Logan Sheridan

Graduate Theses, Dissertations, and Problem Reports (ETD)

For satellites in Low Earth Orbit, the drag coefficient is a major area of uncertainty. Researchers at the Los Alamos National Laboratory have created a Response Surface Modeling (RSM) toolkit to provide the community with a resource for simulating and modeling satellite drag coefficients in Free Molecular Flow. The toolkit combines the high fidelity of numerical simulation techniques with the speed of regression modeling. Specifically, it uses a training sample of drag coefficients simulated with the Test Particle Monte Carlo method with the robust Gaussian Process Regression approach. The RSM toolkit is the prime process to become a toolkit of …

Putting Policy In Its Place: Policy Enactment And Engagement Through A Multiscalar Policy-Shed Framework, Barbara L. Maclennan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The objective of this research is to examine the spatial components integral to policy formation, implementation, and evaluation. The research uses solid waste as a case study to explore a multiscalar GIS policy-shed framework. To this end, the goal of this dissertation is to examine the spatial nature of public policy. The research applies spatial concepts and multiscalar methodological applications embedded within GIS and geovisualization to explore the complex spaces surrounding public policy implementation and evaluation.

Integration Of Deep Hashing And Channel Coding For Biometric Security And Biometric Retrieval, Veeru Talreja

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the last few years, the research growth in many research and commercial fields are due to the adoption of state of the art deep learning techniques. The same applies to even biometrics and biometric security. Additionally, there has been a rise in the development of deep learning techniques used for approximate nearest neighbor (ANN) search for retrieval on multi-modal datasets. These deep learning techniques knows as deep hashing (DH) integrate feature learning and hash coding into an end-to-end trainable framework. Motivated by these factors, this dissertation considers the integration of deep hashing and channel coding for biometric security and …

Examining The Effects Of Background Noise On Contextualized Word Learning, Caitlin Alyssa Ross

Graduate Theses, Dissertations, and Problem Reports (ETD)

Despite redundancy in the acoustic speech signal, both children and adults demonstrate difficulty listening and learning in noise. Research has shown that the acoustic parameters of classrooms and common study places, such as libraries and coffee shops, are often exposing students daily to unhealthy levels of background noise and distraction as they attempt to access and retain new information. While younger children may encounter new words via deliberate instruction in a classroom setting, older students are more likely to access new vocabulary indirectly via reading or self-study in noisy environments often of their own choosing. In both scenarios, accurate perception …

Sustainability Assessment Of Direct Energy Deposition (Ded) Based Hybrid Manufacturing Using Life Cycle Assessment (Lca) Method, Faujia Islam

Graduate Theses, Dissertations, and Problem Reports (ETD)

As sustainability has emerged as a highlight for almost every field over the last few decades, the manufacturing field is no exception. Generally, additive manufacturing performs better than traditional manufacturing in terms of sustainability because of its lean energy- and material usage. Previous studies have compared the sustainability performance between traditional and additive manufacturing, but hybrid manufacturing was not focused upon much. In this paper, the life cycle assessment method is used to analyze and compare the energy consumption and environmental impact of direct energy deposition (DED) based hybrid manufacturing and traditional manufacturing “CNC milling” process for a turbine blade. …

Traditional And Modern Breeding Strategies Towards Developing Resilient Crops: Two Case Studies In Tomato, Estefania Tavares Flores

Graduate Theses, Dissertations, and Problem Reports (ETD)

Crop designing for resilience traits to produce satisfactorily under adverse conditions and scenarios is a priority for the future of global food security. In this thesis, two different approaches addressing major stress factors for tomato cropping are presented. We first aimed to domesticate tomato de novo as a high-salinity resistant crop using the wild relative, S. cheesmaniae via gene editing. We conducted single-gene and multiplex knock-out strategies using CRISPR/Cas9 genome editing to create loss-of-function alleles for the domestication-related genes BIF, CycB, J2, EJ2, MULTI, SP, SP5G, and FW11.3 in order to create a novel, halophyte tomato harboring an inherent high-salinity …