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Articles 1651 - 1680 of 4601
Full-Text Articles in Entire DC Network
Molecular Characterization Of Lhx8, An Oocyte-Specific Transcription Factor, And Its Interacting Proteins In Rainbow Trout And Cattle, Liyuan Fu
Graduate Theses, Dissertations, and Problem Reports (ETD)
LIM homeobox 8 (Lhx8) is an important transcription factor that is preferentially expressed in germ cells. Lhx8 null mice are infertile due to lack of oocytes and impairment of the transition from primordial follicles to primary follicles. Lhx8 deficiency also affects the expression of many important oocyte-specific genes. To date, no attempts have been made to investigate the existence of any cellular factors that might interact with Lhx8 protein in oocytes and early embryos. In this study, we report the characterization of rainbow trout and bovine Lhx8 genes and identification of important germ cell-specific nuclear factors that interact with Lhx8 …
Homeplace, Megan Leigh Gainer
Homeplace, Megan Leigh Gainer
Graduate Theses, Dissertations, and Problem Reports (ETD)
The sculptural work presented in this thesis and the accompanying exhibition showcase the ideas of memory, its fallacy, and why certain objects become tied to the idea of a specific time, place, and culture. Using my own personal experiences growing up in rural West Virginia, I call upon traditional crafting techniques to relay a sense of nostalgia commonly found throughout Appalachia. The expression of the hand present throughout the work highlights the importance placed on these seemingly mundane objects, which hold a special place in my history.
Distribution And Efficacy Of Chemotherapeutics In The Treatment Of Preclinical Brain Metastases Of Breast Cancer, Tori Terrell Hall
Distribution And Efficacy Of Chemotherapeutics In The Treatment Of Preclinical Brain Metastases Of Breast Cancer, Tori Terrell Hall
Graduate Theses, Dissertations, and Problem Reports (ETD)
Brain metastases are a critical, life-threatening problem for women with advanced metastatic breast cancer. Approximately 80% of women with disseminated central lesions are unable to survive the first year after diagnosis. Despite the breakdown of the blood-brain barrier, chemotherapeutics have limited penetration and distribution into brain metastases and are unable to induce cytotoxicity in the tumor. Limiting the development of new treatments for brain metastases of breast cancer, there are no commercially available in vitro models available that accurately model, and mimic the functionality of, the in vivo blood-tumor barrier (BTB). In an attempt to address the aforementioned problem, the …
Development Of Engine Activity Cycles For The Prime-Movers Of Unconventional Well Completion, Robert S. Heltzel
Development Of Engine Activity Cycles For The Prime-Movers Of Unconventional Well Completion, Robert S. Heltzel
Graduate Theses, Dissertations, and Problem Reports (ETD)
The US natural gas extraction industry has grown by 25% over the past decade. This has encouraged the well completion industry to utilize produced natural gas to meet power demands previously obtained with diesel fuel. The major "prime-movers" of diesel fuel consumption are over-the-road (OTR) trucks, high horsepower drilling, and high horsepower hydraulic fracturing engines. The US Department of Energy (DOE) recently granted West Virginia University (WVU) funding, under agreement DE-FE0013689, to "Assess Fugitive Methane Emissions Impact Using Natural Gas Engines in Unconventional Resource Development." As part of the funding, WVU was tasked with creating engine activity cycles representative of …
Somewhat Familiar, Brett Herron
Somewhat Familiar, Brett Herron
Graduate Theses, Dissertations, and Problem Reports (ETD)
My MFA written thesis addresses work completed and shown in a thesis exhibition at West Virginia University as well as significant influences to my studio process. While my focus is printmaking, the work presented in the exhibition consists of several sculptural and photographic pieces. This thesis, along with the supporting exhibition, will address my investigations into extending Minimalism's anonymity and relational aesthetics while adhering to my own predetermined artistic parameters. The work is concerned with observed form and composition along with the transformation of mundane and knowable materials into uncertain sculptures that highlight their physical properties. I emphasize the material …
Design, Fabrication And Characterization Of Photonic Crystal Light-Emitting Diodes For Solid-State Lighting, Anand Kadiyala
Design, Fabrication And Characterization Of Photonic Crystal Light-Emitting Diodes For Solid-State Lighting, Anand Kadiyala
Graduate Theses, Dissertations, and Problem Reports (ETD)
Residential, commercial, and industrial lighting applications contribute to ∼19% of total energy consumption worldwide. The application of more efficient sources of lighting, such as solid-state lighting (SSL) sources, could result in potential energy savings of about 65%. Current technologies employ semiconductor-based light-emitting diodes (LEDs) as the core elements of SSL devices to provide general-purpose light in a wide range of color temperatures. However, there still exists several device level issues, such as poor material quality, low quantum efficiencies, large percentage of light being trapped, etc. These non-idealities are barriers for SSL sources replacing incandescent and compact fluorescent sources on an …
3d Seismic Interpretation, Mechanical Stratigraphy And Production Analysis Of The Marcellus Shale In Northern West Virginia, Mollie K. Kish
3d Seismic Interpretation, Mechanical Stratigraphy And Production Analysis Of The Marcellus Shale In Northern West Virginia, Mollie K. Kish
Graduate Theses, Dissertations, and Problem Reports (ETD)
The Marcellus shale is one of the most developed unconventional shale gas reservoirs in the world with a calculated 84.5 trillion cubic feet in proved natural gas reserves in Pennsylvania and West Virginia. To better exploit this resource all geological aspects of the Marcellus shale are being studied. In this study, mechanical stratigraphy and interpreted seismic fracture zones within the Marcellus shale are examined. These geologic criteria are assessed for potential to impact gas production by analyzing the gas production of fourteen horizontal Marcellus shale wells within and around the study area.;Mechanical stratigraphy is evaluated from the top of the …
An Energy-Efficient Reconfigurable Mobile Memory Interface For Computing Systems, Majid Jalali Far
An Energy-Efficient Reconfigurable Mobile Memory Interface For Computing Systems, Majid Jalali Far
Graduate Theses, Dissertations, and Problem Reports (ETD)
The critical need for higher power efficiency and bandwidth transceiver design has significantly increased as mobile devices, such as smart phones, laptops, tablets, and ultra-portable personal digital assistants continue to be constructed using heterogeneous intellectual properties such as central processing units (CPUs), graphics processing units (GPUs), digital signal processors, dynamic random-access memories (DRAMs), sensors, and graphics/image processing units and to have enhanced graphic computing and video processing capabilities. However, the current mobile interface technologies which support CPU to memory communication (e.g. baseband-only signaling) have critical limitations, particularly super-linear energy consumption, limited bandwidth, and non-reconfigurable data access. As a consequence, there …
Compressing Genome Resequencing Data, Aliya Farheen
Compressing Genome Resequencing Data, Aliya Farheen
Graduate Theses, Dissertations, and Problem Reports (ETD)
Recent improvements in high-throughput next generation sequencing (NGS) technologies have led to an exponential increase in the number, size and diversity of available complete genome sequences. This poses major problems in storage, transmission and analysis of such genomic sequence data. Thus, a substantial effort has been made to develop effective data compression techniques to reduce the storage requirements, improve the transmission speed, and analyze the compressed sequences for possible information about genomic structure or determine relationships between genomes from multiple organisms.;In this thesis, we study the problem of lossless compression of genome resequencing data using a reference-based approach. The thesis …
An Exploration Of The Relationships Between Chronic Pain, Inflammation, And Herbal Medicine, Termeh Feinberg
An Exploration Of The Relationships Between Chronic Pain, Inflammation, And Herbal Medicine, Termeh Feinberg
Graduate Theses, Dissertations, and Problem Reports (ETD)
Introduction: Inflammation is often a component of chronic pain, yet its potential role in fibromyalgia syndrome (FMS) remains inconclusive. FMS is a complex chronic pain condition affecting ~2% of the population; management is challenging and treatment options remain limited. Many herbs contain anti-inflammatory properties, and herbs indicated for analgesia and rheumatic conditions have traditionally been used in Appalachia. Despite the popularity of herbs in the US, determinants and patterns of herbal use with regard to pain management have not been well studied, particularly in Appalachia, where prevalence of chronic pain and related comorbid conditions is high and access to medical …
Influence Of The Gondwanide Magmatic Arc And Cape Fold Belt On The Karoo Basin - South Africa, Clyde Pitt Findlay Iii
Influence Of The Gondwanide Magmatic Arc And Cape Fold Belt On The Karoo Basin - South Africa, Clyde Pitt Findlay Iii
Graduate Theses, Dissertations, and Problem Reports (ETD)
The Permian Ecca Group in South Africa preserves a thick succession of clastic basin fill, including mud-rich turbidite sequences and hemipelagic mudstone units. Provenance of mud influx into the basin is an important constraint for understanding the tectonic processes influencing regional basin development and distribution of organic-rich Lower Ecca Group mudstone and subsequent depositional style of the Upper Ecca Group turbidite systems. In this study, we interpret the Ecca Group mudstones were sourced by the Cape Fold Belt and Gondwanide Magmatic Arc based on geochemistry and mineralogy of 38 mudstone samples. Muscovite and high quartz content (average 32.9%) indicate metamorphic …
Rehabilitation Of Structures Below The Earths Surface Using Fibre Reinforced Polymer Shell Augers And Fabrication Of Plastic Compounder, Kumar Venkatesh Karri
Rehabilitation Of Structures Below The Earths Surface Using Fibre Reinforced Polymer Shell Augers And Fabrication Of Plastic Compounder, Kumar Venkatesh Karri
Graduate Theses, Dissertations, and Problem Reports (ETD)
Many ageing highway bridges are in distress, requiring urgent repairs or rehabilitation. About 10% of the total highway bridges require rehabilitation in United States of America (Houlihan, April 2015). Reconstruction of these bridges requires large sums of money and time consuming conventional rehab schemes. Herein, a novel rehab scheme with Fiber Reinforced Polymer (FRP) composites has been evaluated in the laboratory as FRPs exhibit high strength to weight ratio, high stiffness and excellent corrosion resistance. Current methods to repair pile systems are limited by access issues as the piles are extended typically underwater and below the mudline. Traditional methods require …
A Radiological Survey Of Two Bruker D8 Advance Xrd Instruments Located In Separate Quality Control Laboratories, Justin Anthony Meador
A Radiological Survey Of Two Bruker D8 Advance Xrd Instruments Located In Separate Quality Control Laboratories, Justin Anthony Meador
Graduate Theses, Dissertations, and Problem Reports (ETD)
A Radiological Survey of Two Bruker D8 Advance XRD Instruments Located in Separate Quality Control Laboratories By Justin Meador In October 2016, XYZ Laboratories requested assistance with conducting a radiological survey of each of their Bruker D8 Advance XRD instruments to determine compliance with Title 64 West Virginia Legislative Rule, Department of Health, Series 23, Radiological Health Rules (64CSR23) and 10 CFR Part 20 – Standards for Protection Against Radiation in regards to the X-Ray radiation being emitted during operation of the units. A review of ionizing radiation, sources of radiation, biological effects, unit descriptions, Federal and State standards, description …
Three Essays Analyzing The Pricing Of A Community Supported Agriculture System, Dwayne Bauknight
Three Essays Analyzing The Pricing Of A Community Supported Agriculture System, Dwayne Bauknight
Graduate Theses, Dissertations, and Problem Reports (ETD)
The current landscape of small farms is approaching a major shift as more and more small farms are poised to come onto open marketplace around urban areas. A different farming business model called Community Supported Agriculture (CSA) has been utilized as new way for farmers to potentially earn above average revenue. However, small farmers still feel dissatisfied with their overall farm income, but when implementing the CSA business model the producers do feel that the CSA enhances their overall income satisfaction. Three essays were developed to examine this predicament. The first essay examined possible economic pricing models that a CSA …
Effects Of Parent And Peer Behaviors On Adolescent Sexual Behavior: Are Positive And Negative Peer Behaviors Moderators?, S. Michelle Watson
Effects Of Parent And Peer Behaviors On Adolescent Sexual Behavior: Are Positive And Negative Peer Behaviors Moderators?, S. Michelle Watson
Graduate Theses, Dissertations, and Problem Reports (ETD)
Adolescents and young adults account for a significantly high proportion of unintended pregnancy and sexually transmitted infection cases in the United States. According to Jessor's Problem Behavior Theory, combined protective factors, such as exposure to positive parenting and peer behaviors, create an environment that is supportive of conventional behaviors and discouraging of problem behaviors. There is an extensive amount of literature on parent and peer influences on adolescent sexual behavior but few studies address the interactive influence of both parent and peer behaviors on adolescent sexual risk-taking. The purpose of this study was to examine the relationship between maternal supportiveness …
Migratory Genomics Of Lake Sturgeon, Justine Whitaker
Migratory Genomics Of Lake Sturgeon, Justine Whitaker
Graduate Theses, Dissertations, and Problem Reports (ETD)
Lake sturgeon are large, freshwater fish and the only species of sturgeon native to the Great Lakes. Their historic range extends from the Hudson Bay, down through the Great Lakes and into the Mississippi River basin. In the early 1900's, sturgeon became a valuable fishery and were soon overfished for both meat and caviar. This, in combination with damming, pollution, and habitat degradation, caused a drastic decline in their population. Some populations were extirpated, while others have been reduced to 1% of their historic population size (Auer, 1996). The St. Clair-Detroit River System (SCDRS) hosts one of the largest lake …
Instructional Coaches In West Virginia: Who They Are And What They Do, Mary Lynn Westfall
Instructional Coaches In West Virginia: Who They Are And What They Do, Mary Lynn Westfall
Graduate Theses, Dissertations, and Problem Reports (ETD)
Implementing practices and programs into a school and making sure they are successful requires a collaborative effort among all involved in the school. With the expectations of what a school is to provide for students and faculty, school principals have been charged with serving as the building manager and instructional leader of the school. Teacher leadership has flourished as principals seek assistance from other education professionals. Instructional, or academic, coaches are formal teacher leaders who may work with teachers and principals. They can work closely with teachers to improve teaching practices and work to overcome the isolationism that traditionally exists …
The Biased Bystander: How Homophobia Affects Intervention In Physical Fights, R. Kyle Saunders
The Biased Bystander: How Homophobia Affects Intervention In Physical Fights, R. Kyle Saunders
Graduate Theses, Dissertations, and Problem Reports (ETD)
Sociologists, criminologists and psychologists have offered a number of theories to understand bystander intervention in emergency situations in general. Most notably, the bystander effect argues that as the number of bystanders to an incident increases, the less likely someone is to intervene. However, the likelihood of intervention could also be dependent on the personal biases of the observers. A bystander's contempt or dislike for particular victims (homosexuals, minorities, women, etc.) may influence his or her willingness to intervene. This research explores, through the use of vignette experiments, the extent to which a bystander's homophobia influences their willingness to intervene on …
An Analysis And Validation Of An Online Photographic Identity Exposure Evaluation System, Elliott V. Iannello
An Analysis And Validation Of An Online Photographic Identity Exposure Evaluation System, Elliott V. Iannello
Graduate Theses, Dissertations, and Problem Reports (ETD)
The rapid growth in volume over the last decade of personal photos placed online due to the advent of social media has made users highly susceptible to malicious forms of attack. A system was proposed and constructed using Open Source technologies capable of acquiring the necessary data to conduct a measurement of online photographic exposure to aid in assessing a user's digital privacy. The system's effectiveness at providing feedback on the level of exposure was tested by using a controlled set of three subjects. Each subject provided three training photos each that simulated what would be easily ascertainable from social …
Why Do Some Grant Proposals Win The Funds And Others Fail? Genre Analysis For The Abstracts Of Grant Proposals Submitted By The Health Science Center Researchers To The National Institutes Of Health, Yassin Ismaeel
Graduate Theses, Dissertations, and Problem Reports (ETD)
This study is an endeavor to investigate the textual linguistic factors that lead to successful grant proposals. Grant proposals have different sections. The focus was on the abstracts of grant proposals. The abstract is the first most piece read by the funding agency. There are many important contextual and situational conditions that directly affect the winning of the funds. This current study aims at the linguistic aspects of the abstracts. Twenty abstracts, chosen from the National Institutes of Health (NIH) website, were used as unit samples for the analysis. The coding units were the sentences existed in these texts. The …
Impact Of Serving As An Extension Camping Instructor On Life Skills Development., Jeffery A. Davis Jr.
Impact Of Serving As An Extension Camping Instructor On Life Skills Development., Jeffery A. Davis Jr.
Graduate Theses, Dissertations, and Problem Reports (ETD)
The purpose of this study was to determine if West Virginia University Extension Camping Instructors were influencing the life skill development of 4-H youth while also developing life skills of their own. This study utilized the unique perceptions of Extension Camping Instructors who were employed from the summer of 2007 to October of 2015 by examining their current level of life skills, how they felt being employed as an Extension Camping Instructor influenced the development of each skill, and how they felt their role impacted the life skill development of 4-H youth with whom they had worked. A descriptive survey …
A Qualitative Investigation Of Completed And Averted School Shootings: Deciphering The Characteristics That Prevent School Shootings, Jonathan Page
A Qualitative Investigation Of Completed And Averted School Shootings: Deciphering The Characteristics That Prevent School Shootings, Jonathan Page
Graduate Theses, Dissertations, and Problem Reports (ETD)
The purpose of this study was to explore the differences between completed school shootings and averted school shootings in order to gain a better understanding of ways to prevent school shootings. The following research question guided this study: What are the similarities and differences between schools in which a shooting occurred and schools in which a shooting was averted? To answer this question, this study compared school shootings and averted school shootings in K-12 schools between January 2007 and December 2013, searching for general themes to analyze in order to add to the literature on averted school shootings. This study …
Evaluating The Effect Of Feed Mixing And Sampling Methodologies On Nutrient Analysis And The Inclusion Of A Novel Protease In Broiler Diets, Danielle A. Reese
Evaluating The Effect Of Feed Mixing And Sampling Methodologies On Nutrient Analysis And The Inclusion Of A Novel Protease In Broiler Diets, Danielle A. Reese
Graduate Theses, Dissertations, and Problem Reports (ETD)
Proper poultry feeding requires a homogenous mixture of macro and micro ingredients to ensure feed nutrients are being supplied to meet bird requirements. Samples of complete feed may be taken during manufacture and analyzed for nutrient content in order to estimate if nutrients are present in feed in accordance to diet formulation. However, variables associated with mixing and feed sampling may influence the results of nutrient analysis, thus over or under estimating the formula comparison. The objective of this study was to vary mix time, sample location, sample number, and sample blending technique on nutrient analysis. Ingredients were mixed in …
Music Videos As Meaningful Entertainment? Psychological Responses To Audio-Visual Presentations Of Song Narratives, Lea Margarete Schlue
Music Videos As Meaningful Entertainment? Psychological Responses To Audio-Visual Presentations Of Song Narratives, Lea Margarete Schlue
Graduate Theses, Dissertations, and Problem Reports (ETD)
Combining auditive, visual, and textual elements in a unique way, music videos are currently one of the most popular and viral forms of entertainment media. Narrative music videos, in particular, engage their viewers by visually communicating the meaning of a song and its lyrics, which possibly employs them as a useful tool to communicate social, political and cultural messages to a broad audience, and implicates their social and cultural relevance. The purpose of this study was to test whether visual presentations of song narratives (as in music videos) foster a more transporting, engaging, enjoyable, and appreciative entertainment experience than listening …
A Learning History Study Of Sustainable Management In Producing An Inaugural Solar Decathlon Entry, Dana Shearer
A Learning History Study Of Sustainable Management In Producing An Inaugural Solar Decathlon Entry, Dana Shearer
Graduate Theses, Dissertations, and Problem Reports (ETD)
A Learning History approach was used to study the processes and outcomes of West Virginia University's inaugural (2013) Solar Decathlon team as it planned and executed its entry to the competition. In this competition, the product must be a house that meets several standards for sustainable management of material and energy resources. This study conceives of the human resources required to produce an entry as a complementary valuable resource that also can be managed more or less sustainably. Applying principles of sustainable management to evaluate the team's process and the transmission of knowledge to future teams, analysis of the experiences …
Bone Marrow Microenvironment Regulation Of Bcl6 In Acute Lymphoblastic Leukemia, William Lee Slone
Bone Marrow Microenvironment Regulation Of Bcl6 In Acute Lymphoblastic Leukemia, William Lee Slone
Graduate Theses, Dissertations, and Problem Reports (ETD)
Acute lymphoblastic leukemia (ALL) is a hematological malignancy with approximately 6000 newly diagnosed cases every year. Although ALL is the most common malignancy in children, it can occur in patients of all ages. Great strides have been made in the treatment of ALL and remission rates are at all-time highs. However, relapse rates have remained relatively consistent, and relapse continues to be correlated with a poor prognosis in patients with ALL. As the site of origin and progression of ALL, the bone marrow microenvironment (BMM) is important in regulating tumor cell quiescence and proliferation. Of clinical relevance is the frequency …
Design And Development Of An Online Course For Careers In The Equine Industry, Crystal Elizabeth Smith
Design And Development Of An Online Course For Careers In The Equine Industry, Crystal Elizabeth Smith
Graduate Theses, Dissertations, and Problem Reports (ETD)
The equine industry provides 640,000 jobs annually in the United States. Spending by suppliers and employees generates additional jobs for a total employment impact of 1.4 million full time equivalent (FTE) jobs. There are horses in every state, and over 4.6 million people are involved in the equine industry as owners, service providers, employers and volunteers. Overall, the horse industry directly contributes over {dollar}39 billion dollars annually to the US economy (American Horse Council, 2005). Students commonly recognize hands-on careers related to owning, training, and breeding horses, or veterinary medicine. However, fewer realize the diverse opportunities as service providers. Students …
Comparisons Of Host Susceptibility To Isogenic Virulent And Hypovirulent [Chv1-Infected] Strains Of Cryphonectria Parasitica Among Castanea Hosts And Plant Tissue Types, Cameron M. Stauder
Comparisons Of Host Susceptibility To Isogenic Virulent And Hypovirulent [Chv1-Infected] Strains Of Cryphonectria Parasitica Among Castanea Hosts And Plant Tissue Types, Cameron M. Stauder
Graduate Theses, Dissertations, and Problem Reports (ETD)
Chestnut blight is a devastating canker disease of numerous Castanea spp. resulting from the infection of wounds by Cryphonectria parasitica. The restoration of American chestnut has been pursued through the generation of blight resistant American x Chinese hybrids and employment of virulence attenuating hypoviruses of C. parasitica. The goals of this study were: 1) to conduct comparisons of host resistance among American (C. dentata), European (C. sativa), Chinese (C. mollisima), and three American x Chinese hybrid generations (B2F2, B2F3, B3F2) produced by The American Chestnut Foundation (TACF) to isogenic virulent and hypovirulent (CHV1) strains of C. parasitica; 2) to validate …
Communicative Solutions Through Technology: An Evaluation Of Esl Textbooks In Brazil, Natalia De Souza Sterci
Communicative Solutions Through Technology: An Evaluation Of Esl Textbooks In Brazil, Natalia De Souza Sterci
Graduate Theses, Dissertations, and Problem Reports (ETD)
Textbooks are the main tools used by teachers and students in English as a Second Language/ English as a Foreign Language (ESL/EFL) teaching settings; Therefore, it is important to select the most appropriate textbook that meets both teachers' and students' needs. This study examines three textbooks commonly used in Brazilian private schools: New Interchange (Richards, 2000), American Headway 1 (Soars & Soars, 2001), and Top Notch 1 (Saslow & Ascher, 2006), all of which are published by non-Brazilian companies, to see how well they address the urgent need for communication-based EFL textbooks in Brazil. The current study seeks to help …
Cooperative Maneuver Enabled Uav Relative Localization, Jared Strader
Cooperative Maneuver Enabled Uav Relative Localization, Jared Strader
Graduate Theses, Dissertations, and Problem Reports (ETD)
The ability to localize itself in an environment is essential for any autonomous vehicle. In applications involving multiple Unmanned Aerial Vehicles (UAVs) such as formation flight, surveillance, and mapping, the relative pose of each UAV provides vital information for multiple vehicles to coordinate effectively. The majority of cooperative localization tasks involving multiple UAVs assume the transformation between reference frames, but this information is not always provided in the absence of landmarks or a Global Positioning System (GPS).;This thesis presents a method for estimating the relative pose of a pair of UAVs using range-only measurements. In this method, there is no …