Digital Commons Network^™

Obese Zucker Rats As A Reverse Translational Model Of Human Left Ventricular Hypertrophy, Mackenzie Shelby Newman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Heart failure is a lifelong disability that for over half of those affected leads to mortality within five years after initial diagnosis. Left ventricular hypertrophy (LVH) is one of the most reliable independent predictors of heart failure. Pathological LVH is irreversible, but early diagnosis is often missed due to its asymptomatic nature. Obese Zucker rats (OZR), which develop obesity due to dysfunctional leptin signaling, naturally exhibit a LVH that mimics the obese human condition. Animal models are necessary because human donor tissue is scarce. The central hypothesis is that genes and proteins that are differentially expressed during development of LVH, …

Family Forest Owners Satisfaction With Timber Transactions, Jeffrey M. Lee

Graduate Theses, Dissertations, and Problem Reports (ETD)

Forest industries in the eastern U.S. rely heavily on family forest owners to supply fiber needs for their mills. As of 2017, 79 percent of West Virginia is classified as forestland and of this roughly 86.5 percent is privately owned. With such a heavy reliance on wood from private forest lands, family forest owner satisfaction is extremely important if companies want to continue harvesting or working with these landowners in the future.

Timber transactions are complex. No two timber transactions are exactly the same. They often involve many different parties apart from the landowner. Site conditions, land cover, and landowner …

The Roman Catholic Ordinary Mass From Circa 1750 To Circa 1820: A Selected Bibliography, Letícia Gabriele Grützmann Januario

Graduate Theses, Dissertations, and Problem Reports (ETD)

Orchestrated masses from the 18th century and early years of the 19th century provide a valuable source of repertoire for contemporary choral conductors. This project will explore composers and works from circa 1750 to 1820 to provide choral conductors with a list of works suitable for programming based on the practical size of vocal and instrumental forces.

Western choral music was born in a church setting. Among all choral genres, the mass is the only genre composed throughout all eras, from medieval until the 20th century. The mass remained a prominent genre during the 18th century despite the secularizing influence …

It’S Just Muzak: Music, Activism, And Advertising., Avery Brzobohaty

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis builds on recent scholarship explaining the relationships between music, advertising, and society through a series of focused case studies in the clothing industry. Globally ubiquitous and reaching all socioeconomic strata, the fashion industry offers a useful focus because, in addition products, it also sells identity. Fashion is a means for individuals to create and express identity by associating themselves with certain brands and styles that help express social, political, economic, and ethical standings as well as gender, sexuality, race, and religion. This thesis considers the ways that sound and music influence the aesthetic and mood of recent fashion …

Route Planning For Long-Term Robotics Missions, Christopher Alexander Arend Tatsch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Many future robotic applications such as the operation in large uncertain environment depend on a more autonomous robot. The robotics long term autonomy presents challenges on how to plan and schedule goal locations across multiple days of mission duration. This is an NP-hard problem that is infeasible to solve for an optimal solution due to the large number of vertices to visit. In some cases the robot hardware constraints also adds the requirement to return to a charging station multiple times in a long term mission. The uncertainties in the robot model and environment require the robot planner to account …

Evaluation Of Salmonella Enteritidis And Escherichia Coli O157:H7 Volatile Organic Compound Analysis For Food Safety Monitoring: A Preliminary Study, Jessica E. Lemley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Food borne illness has the potential to impact every point of production from producers to consumers. Food product recalls are common due to the presence of food borne illness causing bacteria. Detection of volatile organic compounds (VOC) have the potential to reduce the number of illnesses and recalls through application of additional monitoring of food products like those most commonly recalled. The objective of this research was to 1) explore the use of closed-loop headspace analysis coupled with gas chromatography-mass spectrometry (GC-MS) on food borne illness causing bacteria and 2) examine the VOC profile of Escherichia coli serotype O157:H7 in …

A Delphi Study Exploring The Impact And Feasibility Of Entrepreneurial Initiatives In College/University Kinesiology Programs, Cory Breithoff

Graduate Theses, Dissertations, and Problem Reports (ETD)

As public revenue sources dwindle, and society urges institutions to freeze their ever-increasing tuition rates, universities must be creative to increase their internal revenue. While kinesiology programs have begun to discuss such methods, they must also evaluate what is feasible and financially impactful. The purpose of this study was to gain a consensus of opinion regarding the impact and feasibility of entrepreneurial initiatives in higher education and to generate a list of facilitators and barriers that may impact the implementation. A total of 20 expert panelists comprised of higher education kinesiology administrators participated in a two-round Modified Delphi study to …

Estimating Refactoring Efforts For Architecture Technical Debt, Samir Deeb

Graduate Theses, Dissertations, and Problem Reports (ETD)

Paying-off the Architectural Technical Debt by refactoring the flawed code is important to control the debt and to keep it as low as possible. Project Managers tend to delay paying off this debt because they face difficulties in comparing the cost of the refactoring against the benefits they gain. For these managers to decide whether to refactor or to postpone, they need to estimate the cost and the efforts required to conduct these refactoring activities as well as to decide which flaws have higher priority to be refactored among others.

Our research is based on a dataset used by other …

An Examination To Pathways Powering Car Using Clean Energy, Marina Miranda

Graduate Theses, Dissertations, and Problem Reports (ETD)

Traditional vehicles powered by internal combustion engines contribute significantly to increasing emissions of greenhouses gasses (GHG). There has been increasing interest in powering vehicles using green energy include using electricity produced by wind turbine and solar panel. The green electricity can be used to directly charge the Battery Electric Vehicles (BEV), or producing hydrogen as fuel for Fuel Cell Electric Vehicles (FCEV) by converting electrical energy to hydrogen (H₂) through water electrolysis. The low energy density H₂ produced can be stored on board as either compressed H₂ or liquefied H₂.

This research examines the …

Sustainability-Based Expert System For Additive Manufacturing And Cnc Machining, Josage Chathura Pamuditha Perera

Graduate Theses, Dissertations, and Problem Reports (ETD)

The development of technologies which enable resource efficient production is of paramount importance for the continued advancement of the manufacturing industry. In order to ensure a sustainable and clean energy future, manufacturers should be able to contrast and validate existing manufacturing technologies on a sustainability basis. In the post COVID-19 era of enterprise management, the use of artificial intelligence to simulate human expert decision making abilities will open new doors to achieving heightened levels of productivity and efficiency. The introduction of innovative technologies such as CNC machining and 3D printing to production systems has redefined the manufacturing landscape in a …

Allopurinol Alters The Expression Of Cytokines And Mediators Of Immune Cells In The Systemic 2 Tissue By Decreasing Plasma Urate., Lundrim S. Marku

Graduate Theses, Dissertations, and Problem Reports (ETD)

Diminished levels of urate have been linked to oxidative stress in birds and mammals. Urate, a major antioxidant that lowers reactive oxygen/nitrogen species (ROS/RNS), is thought to ameliorate the effects. The relationship between reduced urate, the immune system and the pathogenesis of the intestine, the liver or the brain has not been well characterized in avians. Moreover, recent studies have proposed that an increased permeability in the intestine due to some insult can induce inflammation in peripheral organs such as the brain. Allopurinol, a relatively toxic purine analogue that serves as a xanthine oxidase inhibitor, reduces urate levels which can …

The “Other” Teacher: Understanding The Experience Of Graduate Teaching Assistants In Neoliberal Teacher Education Settings, Jing Zhang

Graduate Theses, Dissertations, and Problem Reports (ETD)

In this study, I critically examine how graduate teaching assistants’ (GTAs’) experiences are discursively shaped by the exercise of power in neoliberal higher education contexts and hence, to reveal the hidden aspects of educational institutions, which are central to our understandings about the meaning of truth, fairness, and equity embedded in neoliberal academic settings. To understand the experiences of graduate teaching assistants in this neoliberal teacher education setting, the major research questions of this study explore how the different identities that GTAs possess influence their interactions with the neoliberal higher education context and how they navigate as well as resist …

A Video Decision Aid For The West Virginia Post: A Randomized, Controlled Trial, Jarred Vicente Gallegos

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Physician Orders for Life Sustaining Treatment (POLST) allows patients to express preferences for end-of-life medical decisions. Although POLST forms are used throughout the United States, evidence is lacking about the quality of the decision-making process of individuals completing these forms. The use of a decision aid developed for the POLST could ensure that patients completing these forms are informed, confident, and certain of their treatment decisions. The purpose of the study was to develop and evaluate a video decision aid for the West Virginia POST. 64 English-speaking, community-dwelling adults (50+), with no evidence of cognitive impairment, were recruited to …

Searching For Needles In The Cosmic Haystack, Thomas Ryan Devine

Graduate Theses, Dissertations, and Problem Reports (ETD)

Searching for pulsar signals in radio astronomy data sets is a difficult task. The data sets are extremely large, approaching the petabyte scale, and are growing larger as instruments become more advanced. Big Data brings with it big challenges. Processing the data to identify candidate pulsar signals is computationally expensive and must utilize parallelism to be scalable. Labeling benchmarks for supervised classification is costly. To compound the problem, pulsar signals are very rare, e.g., only 0.05% of the instances in one data set represent pulsars. Furthermore, there are many different approaches to candidate classification with no consensus on a best …

On Demand Nanoscale Phase Manipulation Of Vanadium Dioxide By Scanning Probe Lithography, Dustin Schrecongost

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation focuses on nanoscale phase manipulations of Vanadium Dioxide. Nanoscale control of material properties is a current obstacle for the next generation of optoelectronic and photonic devices. Vanadium Dioxide is a strongly correlated material with an insulator-metal phase transition at approximately 345 K that generates dramatic electronic and optical property changes. However, the development of industry device application based on this phenomenon has been limited thus far due to the macroscopic scale and the volatile nature of the phase transition. In this work these limitations are assessed and circumvented.

A home-built, variable temperature, scanning near-field optical microscope was engineered …

Interpersonal Influences On Interpretation Of Workplace Sexual Harassment, Rachael E. Purtell

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this thesis is to investigate how women interpret and respond to incidents of sexual harassment at work, in the context of both their romantic relationships and workplace cultures. Incorporating Ambivalent Sexism Theory (Fiske & Glick, 1995) to measure sexist attitudes, I presumed that their own, their partners’ and their presumed workplace’s sexism scores for both subsets would be linked to the women’s perceptions and behavioral intentions in response to being sexually harassed at work. Participants were 145 heterosexual adult women, employed full-time and in self-defined committed heterosexual relationships. Each completed a survey that included the Ambivalent …

The Wiring Logic Of Identified Serotonergic Neurons Across Olfactory Networks In Drosophila, Kaylynn E. Coates

Graduate Theses, Dissertations, and Problem Reports (ETD)

Serotonin is a ubiquitous neuromodulator that confers flexibility in networks to modulate a wide array of behavioral and physiological processes. However, due to the complexity and heterogeneity of serotonergic systems, it has been challenging to determine the patterns of connectivity as well as the physiological contexts that influence individual serotonin neurons. In this dissertation, I use two serotonergic neurons which innervate the Drosophila olfactory system, the CSDns, as a model to explore these broad questions comprehensively using anatomical approaches. I first show that the CSDns have distinct connectivity relationships with populations of antennal lobe principal olfactory neurons and that their …

West Virginia Dentists' Perception Of The Knowledge And Skills Of Two Vs. Four Year Dental Hygiene Graduates, Kaitlyn M. Mcquain

Graduate Theses, Dissertations, and Problem Reports (ETD)

The entry level for the dental hygiene profession has, historically been an associate degree. In 2016 the American Dental Hygiene Association (ADHA) approved the Bachelor’s Degree level of education as the preferred for entry level degree. This study is to determine practicing West Virginia dentists preference for the education level of their entry-level dental hygiene employees. There were 1020 surveys electronically distributed to practicing WV dentists to obtain their opinions and preferences. WVU Research Electronic Data Capture (REDCap) was used to determine response percentages and Chi-square statistics were used to compare 2017 to 2019 response rates. Between 2016-2017 and 2018-2019, …

The Idea Of A Citizen: The Role Of Higher Education Institutions In The Development Of Citizens And An Exploration Of Innovative Teaching Techniques To Aid In The Process, Eric Matthew Myers

Graduate Theses, Dissertations, and Problem Reports (ETD)

This work seeks to explain how institutions of higher education and political science educators within those institutions can develop students into citizens. Understanding the role of each (institution, educator, and student) within American democracy is important and the focus of this research. As the roles of each are demarcated, it becomes clear that higher education institutions and their political science educators have a unique ability to nurture students into citizens with a strong sense of civic purpose and understanding.

The subsequent chapters in this work explore the use of experiential education and other innovative teaching methods to determine if students …

Three Essays On Health Economics And Policy Evaluation, Shishir Shakya

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation consists of three essays on the U.S. Health care policy. Each paragraph below refers to the three abstracts for the three chapters in this dissertation, respectively. I provide quantitative evidence on how much Prescription Drug Monitoring Programs (PDMPs) affects the retail opioid prescribing behaviors. Using the American Community Survey (ACS), I retrieve county-level high dimensional panel data set from 2010 to 2017. I employ three separate identification strategies: difference-in-difference, double selection post-LASSO, and spatial difference-in-difference. I compare how the retail opioid prescribing behaviors of counties, that are mandatory for prescribers to check the PDMP before prescribing controlled substances …

'Making It' Through Migration: Success (Im)Mobility And 'Development' In The Gambia, Martin J. Aucoin

Graduate Theses, Dissertations, and Problem Reports (ETD)

Contemporary scholarly and journalistic literature consistently represents migration from and through The Gambia using the lens of “crisis”. While these representations normally focus on Gambian migration to European states – a movement that is highly politicized – this thesis presents a case study of Gambian migration to a less-politicized destination, North America, in order to explore the relationship between lived experiences and representations of migration absent the discourse of crisis that pervades other scholarly and journalistic works. Drawing on the mobilities paradigm, feminist geographies of migration, critical race theory, transnationalism, and literatures on bordering, humanitarianism and development, I examine, through …

Relating Recharge Mechanisms To Chemical Changes In An Updip Appalachian Coal Mine Discharge: A Case Study From Lambert Run, West Virginia, Matthew Lewis Bell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Impaired drainage from active and abandoned mines degrades the water quality of receiving streams and aquifers. Coal mine drainage (CMD) has been studied for decades in Appalachia, but unknowns and uncertainties are still present, including the influence of mine hydrogeology on the outflow chemistry of above-drainage mines. To evaluate the influence of recharge type on above-drainage mine chemistry, samples were collected every two weeks at a CMD outflow treatment system in Harrison County, West Virginia.

Samples were collected to measure geochemical changes taking place in the mine workings and along the flowpath of the passive treatment system. Samples were divided …

Exploring The User Experiences Of A Bird Id Mobile App Among College Students In Western India, Jayvijay V. Raol

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study explores user experiences of a sample of college age young adults from western India, with a bird ID mobile app. Mobile apps provide an attractive and interactive access to information and their reach and versatility can often bypass challenges of poor infrastructure and lack of access to sources for information. Studies that examine the influence of mobile apps on users’ knowledge and awareness are still in their infancy. Mobile phones and mobile applications have become increasingly prevalent in the educational setting, not only as technology for instructional delivery, but also as a means of improving user experience when …

Early Black Poetry, Social Justice, And Black Children: Receptions Of Child Activism In African American Literary History, Tabitha Lashay Joy Lowery

Graduate Theses, Dissertations, and Problem Reports (ETD)

In spite of the substantial amount of critical work that has been produced on the recovery of early African American literature in the last few decades, our representations of black authors are still limited. Current studies of early African American poets privilege the identification of African American literature with resistance to slavery. This identification has persisted and has made the field one-dimensional. My dissertation provides reception histories of four early black poets—Phillis Wheatley, George Moses Horton, Frances Harper, and Paul Laurence Dunbar—to argue for and present an expansive understanding of African American literature. A thorough examination of these authors’ circulation …

Internalization Of Sociocultural Standards Of Beauty, Perception Of Career Barriers, Depression, And State Physical Appearance Anxiety Among College Women, Adrionia Molder

Graduate Theses, Dissertations, and Problem Reports (ETD)

Women experience barriers that impede progress in a career and career goals, resulting in reduced career-related outcomes. Although gender discrimination has been identified as a contributing factor to the differential career development of men and women in the United States (U.S.), women’s career-related outcomes may be better explained by unaccounted for career barriers. Most notably, internalization of sociocultural standards of beauty, depression, and anxiety have been found to reduce women’s career-related outcomes. Therefore, the goal of this study was to explore career barriers that currently impact women’s career development in the U.S. Based on Social Cognitive Career Theory (Lent, Brown, …

Prosocial Behaviors: The Influence Of Authoritarian Parenting Style On Adolescents’ Prosocial Behaviors Towards Friends And Strangers, Krista-Gay Shaniece Chantal Taylor

Graduate Theses, Dissertations, and Problem Reports (ETD)

Adolescence is the period of development of many negative and positive behaviors. On the positive side, prosocial behaviors are positive behaviors that become more prominent in adolescents. Many of the studies that explore prosocial behaviors have explored it during childhood rather than in adolescence. Additionally, few have assessed specific parenting styles, like authoritarian parenting and its influence on adolescents’ prosocial behaviors within distinct relationships. Therefore, the aims of this study were to assess how the maternal authoritarian parenting style is associated with adolescents’ prosocial behaviors. I also explored how the association between these two variables differ for friends and strangers …

Role Centrality And Shared Activities With Grandchildren: Effects On Grandparent Wellbeing, Madeline Marie Marello

Graduate Theses, Dissertations, and Problem Reports (ETD)

Research shows that physical and mental health are closely linked (Ohrnberger, Fichera, & Sutton, 2017). Further, social role theory states that holding and enacting valued roles, such as grandparenting, can buffer the negative effects of health on depression (Reitzes & Mutran, 2004). Using data from 247 grandparents (Mean age = 66.5; range 42 to 90 years; 46.2% grandfathers), we examined whether grandparent role centrality and engagement with grandchildren altered the effects of physical health on depression. We then explored model differences between 164 custodial and 83 traditional grandparents. We found that for all grandparents the model was of sufficient fit: …

Low-Cost Skewed Redundant Imu Configuration For State-Space Recovery In A Saturated Environment, Levi S. Hubbard

Graduate Theses, Dissertations, and Problem Reports (ETD)

Low-cost sensors for state space determination can be used successfully for ground vehicles, robots, unmanned aerial vehicles, and Internet-of-Things applications. When a high fidelity Inertial Measurement Unit (IMU) cannot be obtained for state space determination, low-cost sensors can be used to satisfactory standards, despite their limitations in capabilities, by using various implementation techniques. The research group was experimentally investigating state space information of an unstable flying vehicle for motion simulation validation. The high fidelity motion capture system would intermittently lose track of the flight vehicle which lost critical flight data.

The goal was to determine the potential of low-cost off-the-shelf …

Image And Video-Based Autism Spectrum Disorder Detection Via Deep Learning, Mindi Ruan

Graduate Theses, Dissertations, and Problem Reports (ETD)

People with Autism Spectrum Disorder (ASD) show atypical attention to social stimuli and aberrant gaze when viewing images of the physical world. However, it is unknown how they perceive the world from a first-person perspective. In this study, we used machine learning to classify photos taken in three different categories (people, indoors, and outdoors) as either having been taken by individuals with ASD or by peers without ASD. Our classifier effectively discriminated photos from all three categories but was particularly successful at classifying photos of people with >80% accuracy. Importantly, the visualization of our model revealed critical features that led …

Characterization Of The Biochemical Properties Of Nudt8, A Novel Coa-Degrading Enzyme That Localizes To The Mitochondria, Evan W. Kerr

Graduate Theses, Dissertations, and Problem Reports (ETD)

Coenzyme A (CoA) is a vital cofactor that is required for a variety of metabolic reactions including the TCA cycle and the synthesis and oxidation of fatty acids, amino acids and ketone bodies. The importance of CoA is underscored by its tight regulation, as prolonged elevations or inability to synthesize adequate amounts of this cofactor lead to severe metabolic dysfunction. Regulation of CoA biosynthesis has been extensively characterized, however less is known about regulation of CoA and its thioesters via degradation. Presently, two CoA-degrading enzymes, Nudt7 and Nudt19 have been identified as regulators of the peroxisomal pool of (acyl-)CoA in …