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Articles 4381 - 4410 of 25411
Full-Text Articles in Entire DC Network
Investigating The Association Between Motor Function, Neuroinflammation, And Recording Metrics In The Performance Of Intracortical Microelectrode Implanted In Motor Cortex, Youjun Li, Monika Goss-Varley, Youjoung Kim, Seth M. Meade, Keying Chen, Jacob M. Rayyan, He Feng, Keith R. Dona, Justin A, Mcmahon, Dawn M. Taylor, Jeffrey R. Capadona
Investigating The Association Between Motor Function, Neuroinflammation, And Recording Metrics In The Performance Of Intracortical Microelectrode Implanted In Motor Cortex, Youjun Li, Monika Goss-Varley, Youjoung Kim, Seth M. Meade, Keying Chen, Jacob M. Rayyan, He Feng, Keith R. Dona, Justin A, Mcmahon, Dawn M. Taylor, Jeffrey R. Capadona
Faculty Scholarship
Long-term reliability of intracortical microelectrodes remains a challenge for increased acceptance and deployment. There are conflicting reports comparing measurements associated with recording quality with postmortem histology, in attempts to better understand failure of intracortical microelectrodes (IMEs). Our group has recently introduced the assessment of motor behavior tasks as another metric to evaluate the effects of IME implantation. We hypothesized that adding the third dimension to our analysis, functional behavior testing, could provide substantial insight on the health of the tissue, success of surgery/implantation, and the long-term performance of the implanted device. Here we present our novel analysis scheme including: (1) …
Pandemic Pause, Heidi K. Brown
Privacy In Pandemic: Law, Technology, And Public Health In The Covid-19 Crisis, Tiffany Li
Privacy In Pandemic: Law, Technology, And Public Health In The Covid-19 Crisis, Tiffany Li
Faculty Scholarship
The COVID-19 pandemic has caused millions of deaths and disastrous consequences around the world, with lasting repercussions for every field of law, including privacy and technology. The unique characteristics of this pandemic have precipitated an increase in use of new technologies, including remote communications platforms, healthcare robots, and medical AI. Public and private actors are using new technologies, like heat sensing, and technologically-influenced programs, like contact tracing, alike in response, leading to a rise in government and corporate surveillance in sectors like healthcare, employment, education, and commerce. Advocates have raised the alarm for privacy and civil liberties violations, but the …
Shareholder Value(S): Index Fund Esg Activism And The New Millennial Corporate Governance, Michal Barzuza, Quinn Curtis, David H. Webber
Shareholder Value(S): Index Fund Esg Activism And The New Millennial Corporate Governance, Michal Barzuza, Quinn Curtis, David H. Webber
Faculty Scholarship
Major index fund operators have been criticized as ineffective stewards of the firms in which they are now the largest shareholders. While scholars debate whether this passivity is a serious problem, index funds’ generally docile approach to ownership is broadly acknowledged.
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/="/">However, this Article argues that the notion that index funds are passive owners overlooks an important dimension in which index funds have demonstrated outspoken, confrontational, and effective stewardship. Specifically, we document that index funds have taken a leading role in challenging management and voting
/="/">against directors in order to advance board diversity and corporate sustainability. We …
How Law Libraries Can Help Tell The Black Lives Matter Movement’S Story, Phebe E. Huderson-Poydras, Ronald E. Wheeler
How Law Libraries Can Help Tell The Black Lives Matter Movement’S Story, Phebe E. Huderson-Poydras, Ronald E. Wheeler
Faculty Scholarship
In Voices Across the Spectrum, our goal is to explore issues, perspectives, and resources that focus on promoting diversity, equality, anti-racism, LGBTQ rights, multicultural outreach and recruitment into the profession, inclusive workplaces, and more. While the first installments of this new column will focus on systemic racism issues, each column will examine different diversity and inclusion issues to help prompt conversations and break down silos within the profession.
Introduction: Health And Human Rights, George J. Annas
Introduction: Health And Human Rights, George J. Annas
Faculty Scholarship
The American health care industry is killing us, and the casualties are mounting daily. Instead of saving lives, it is more often taking them, and not only by failing to seriously confront the coronavirus pandemic and racism in the industry, but also by the way health care is financed.
Comments On Preliminary Draft 6, Jane C. Ginsburg, June M. Besek
Comments On Preliminary Draft 6, Jane C. Ginsburg, June M. Besek
Faculty Scholarship
We briefly reiterate the principal General Comments we made with respect to PD5, because PD6 continues, including in its two new sections, to manifest the same overall shortcomings: (i) the relationship of the draft to the statute remains highly inconsistent; (ii) the Restatement needs a consistent and transparent methodology for restating a statute; and (iii) continuing to carry on without clear methodological principles will undermine the utility of this project and the credibility of the ALI.
Medicaid's Vital Role In Addressing Health And Economic Emergencies, Nicole Huberfeld, Sidney Watson
Medicaid's Vital Role In Addressing Health And Economic Emergencies, Nicole Huberfeld, Sidney Watson
Faculty Scholarship
Medicaid plays an essential role in helping states respond to crises. Medicaid guarantees federal matching funds to states, which helps with unanticipated costs associated with public health emergencies, like COVID-19, and increases in enrollment that inevitably occur during times of economic downturn. Medicaid’s joint federal/state structure, called cooperative federalism, gives states significant flexibility within federal rules that allows states to streamline eligibility and expand benefits, which is especially important during emergencies. Federal emergency declarations give the secretary of Health and Human Services temporary authority to exercise regulatory flexibility to ensure that sufficient health care is available to meet the needs …
Self-Consistent Color-Stellar Mass-To-Light Ratio Relations For Low Surface Brightness Galaxies, Wei Du, Stacy S. Mcgaugh
Self-Consistent Color-Stellar Mass-To-Light Ratio Relations For Low Surface Brightness Galaxies, Wei Du, Stacy S. Mcgaugh
Faculty Scholarship
The color-stellar mass-to-light ratio relation (CMLR) is a widely accepted tool for estimating the stellar mass (M ∗) of a galaxy. However, an individual CMLR tends to give distinct M ∗ for a same galaxy when it is applied in different bands. Examining five representative CMLRs from the literature, we find that the difference in M ∗ predicted in different bands from optical to near-infrared by a CMLR is 0.1 ∼ 0.3 dex. Based on a sample of low surface brightness galaxies that covers a wide range of color and luminosity, we therefore recalibrated each original CMLR in r, i, …
G-Csf And Gm-Csf Are Different. Which One Is Better For Covid-19?, Hillard M. Lazarus
G-Csf And Gm-Csf Are Different. Which One Is Better For Covid-19?, Hillard M. Lazarus
Faculty Scholarship
No abstract provided.
Red Blood Cell Adhesion To Icam-1 Is Mediated By Fibrinogen And Is Associated With Right-To-Left Shunts In Sickle Cell Disease, Erdem Kucukal, Yuncheng Man, Erina Quinn, Neil Tewari, Ran An, Jane A. Little, Umut A. Gurkan
Red Blood Cell Adhesion To Icam-1 Is Mediated By Fibrinogen And Is Associated With Right-To-Left Shunts In Sickle Cell Disease, Erdem Kucukal, Yuncheng Man, Erina Quinn, Neil Tewari, Ran An, Jane A. Little, Umut A. Gurkan
Faculty Scholarship
Sickle cell disease (SCD), which afflicts 100 000 Americans, as well as millions worldwide, is associated with anemia, lifelong morbidity, and early mortality. Abnormal adhesion of sickle red blood cells (RBCs) to activated vascular endothelium may contribute acutely to the initiation of painful vaso-occlusive crises and chronically to endothelial damage in SCD. Sickle RBCs adhere to activated endothelium through several adhesion mechanisms. In this study, using whole blood from 17 people with heterozygous SCD (HbS variant) and 55 people with homozygous SCD (HbSS) analyzed in an in vitro microfluidic assay, we present evidence for the adhesion of sickle RBCs to …
Fixing Informational Asymmetry Through Trademark Search, Jessica Silbey
Fixing Informational Asymmetry Through Trademark Search, Jessica Silbey
Faculty Scholarship
I call this paper a “Levendowski special.” It follows the signature format of much of Professor Levendowski’s prior work which, as in the latest article, recruits a legal tool typically aimed at one set of problems for the purpose of cleverly addressing a different set of problems. Her past articles harnessed copyright law to “fix artificial intelligence’s implicit bias” (2018) and to “combat revenge porn.” (2014). This paper draws on Professor Levendowski’s expertise working in private practice as a trademark attorney to address the problem of surveillance technology opacity. It is a primer on how to investigate trademark …
L’Abbiam Fatta Tutti Noi: Collaboration And Originality In Early Modern Art, James Hutson
L’Abbiam Fatta Tutti Noi: Collaboration And Originality In Early Modern Art, James Hutson
Faculty Scholarship
This article seeks a reevaluation of the collaborative efforts and critical valuation of the Carracci in the frescoes of the Palazzo Magnani. While the significance of the cycle for the development of the nascent baroque style is demonstrable, criticism has focused on attributional issues and the works remain understudied. Since their original biographers struggled over identifying which Carracci was responsible for which scene in the frieze, efforts have been made to carefully dissect the contributions of each. Yet, the collaborative working process of the Carracci, which was recently developed to reform the medieval workshop model of artistic education, was at …
Adverse Events Reported To The United States Food And Drug Administration Related To Caffeine-Containing Products, Andrew R. Jagim, Patrick S. Harty, Karen M. Fischer, Chad M. Kerksick, Jacob L. Erickson
Adverse Events Reported To The United States Food And Drug Administration Related To Caffeine-Containing Products, Andrew R. Jagim, Patrick S. Harty, Karen M. Fischer, Chad M. Kerksick, Jacob L. Erickson
Faculty Scholarship
To examine differences in the frequency and severity of federally reported adverse events between caffeine-containing and non–caffeine-containing products while also identifying the category of caffeine-containing products associated with the highest frequency and severity of adverse events.
Legal Education As Hegemonic Masculinity, Dara Purvis
Legal Education As Hegemonic Masculinity, Dara Purvis
Faculty Scholarship
No abstract provided.
Report To The Wisconsin Office Of Lawyer Regulation: Analysis Of Grievances Filed In Criminal And Family Matters From 2013-2016, Leslie C. Levin, Susan Saab Fortney
Report To The Wisconsin Office Of Lawyer Regulation: Analysis Of Grievances Filed In Criminal And Family Matters From 2013-2016, Leslie C. Levin, Susan Saab Fortney
Faculty Scholarship
In many states, the highest number of docketed grievances arise out of criminal and family law matters. This report analyzes the 4,898 grievances filed with the Wisconsin Office of Lawyer Regulation (“OLR”) in family or criminal law matters during the period from 2013-2016. The OLR provided the data, enabling analysis of the grievances by gender, age, length of time since law school graduation, type of matter, prior experience with diversion or discipline, and geographical location. The data also revealed the frequency of allegations by practice matter, the types of allegations that led to discipline, and the frequency with which lawyers …
Understanding Post Adoption And Guardianship Instability For Children And Youth Who Exit Foster Care: Study Design Options, Nancy Rolock
Understanding Post Adoption And Guardianship Instability For Children And Youth Who Exit Foster Care: Study Design Options, Nancy Rolock
Faculty Scholarship
For children living in foster care, adoption and guardianship are important permanency outcomes when reunification with their biological family is not advisable. Most children living in adoptive or guardianship families do not reenter state custody after adoption or guardianship finalization. But five to 20% of children may experience post adoption and guardianship instability. “Post adoption and guardianship instability†refers to situations in which children who exit foster care to adoptive and guardianship homes no longer reside with their adoptive parent or legal guardian. Instability may be formal (when a child reenters foster care) or informal (when a child lives temporarily …
Have The Aca’S Exchanges Succeeded? It’S Complicated, David K. Jones, Sarah H. Gordon, Nicole Huberfeld
Have The Aca’S Exchanges Succeeded? It’S Complicated, David K. Jones, Sarah H. Gordon, Nicole Huberfeld
Faculty Scholarship
The fight over health insurance exchanges epitomizes the rapid evolution of health reform politics in the decade since the passage of the Affordable Care Act. The ACA's drafters did not expect the exchanges to be contentious; they would expand private insurance coverage to low- and middle-income individuals who were increasingly unable to obtain employer-sponsored health insurance. Yet, exchanges became one of the primary fronts in the war over Obamacare. Have the exchanges been successful? The answer is not straightforward and requires a historical perspective through a federalism lens. What the ACA has accomplished has depended largely on whether states were …
Industry Concentration And Information Technology, James Bessen
Industry Concentration And Information Technology, James Bessen
Faculty Scholarship
Industry concentration has been rising in the US since 1980. Firm operating margins have also been rising. Are these signs of declining competition that call for a new antitrust policy? This paper explores the role of proprietary information technology systems (IT), which could increase industry concentration and margins by raising the productivity of top firms relative to others. Using instrumental variable estimates, this paper finds that IT system use is strongly associated with the level and growth of industry concentration and firm operating margins. The paper also finds that IT system use is associated with relatively larger establishment size and …
When Does A Minor’S Legal Competence To Make Health Care Decisions Matter?, Lois A. Weithorn
When Does A Minor’S Legal Competence To Make Health Care Decisions Matter?, Lois A. Weithorn
Faculty Scholarship
In this article, I examine the role of minors’ competence for medical decision-making in abstract modern American law. The doctrine of parental consent remains the default legal and bioethical framework for health care decisions on behalf of children, complemented by a complex array of exceptions. Some of those exceptions vest decisional authority in the minors themselves. Yet, in American law, judgments of minors’ competence do not typically trigger shifts in decision-making authority from adults to minors. Rather, minors’ decisional capacity becomes relevant only after legislatures or courts determine that the default of parental discretion does not achieve important policy goals …
Clarifying The Default For Anti-Discrimination Statutes, Michael C. Harper
Clarifying The Default For Anti-Discrimination Statutes, Michael C. Harper
Faculty Scholarship
No abstract provided.
Comparison Of Abbott Id Now, Diasorin Simplexa, And Cdc Fda Emergency Use Authorization Methods For The Detection Of Sars-Cov-2 From Nasopharyngeal And Nasal Swabs From Individuals Diagnosed With Covid-19, Daniel D. Rhoads, Sree S. Cherian, Lisa M. Stempak, Christine L. Schmotzer, Navid Sadri
Comparison Of Abbott Id Now, Diasorin Simplexa, And Cdc Fda Emergency Use Authorization Methods For The Detection Of Sars-Cov-2 From Nasopharyngeal And Nasal Swabs From Individuals Diagnosed With Covid-19, Daniel D. Rhoads, Sree S. Cherian, Lisa M. Stempak, Christine L. Schmotzer, Navid Sadri
Faculty Scholarship
No abstract provided.
Border Babies — Medical Ethics And Human Rights In Immigrant Detention Centers, Sondra S. Crosby, George J. Annas
Border Babies — Medical Ethics And Human Rights In Immigrant Detention Centers, Sondra S. Crosby, George J. Annas
Faculty Scholarship
Providing decent medical care for families in U.S. detention centers near the Mexican border has become exceedingly difficult over the past 2 years. Trauma was inflicted on migrants to deter others from attempting to enter the United States. A cornerstone of deterrence was the “zero tolerance” policy that forcibly separated children from their parents at the border. Photographs of children confined in cages horrified Americans, who demanded that the policy be rescinded. It was, but family separations continue and have been made even worse by the Migrant Protection Protocol (MPP) — which the U.S. Supreme Court will most likely review …
Postglacial Recolonization Of North America By Spadefoot Toads: Integrating Niche And Corridor Modeling To Study Species’ Range Dynamics Over Geologic Time, Iulian Gherghel, Ryan Andrew Martin
Postglacial Recolonization Of North America By Spadefoot Toads: Integrating Niche And Corridor Modeling To Study Species’ Range Dynamics Over Geologic Time, Iulian Gherghel, Ryan Andrew Martin
Faculty Scholarship
Understanding the factors that shape species’ distributions is a key topic in biogeography. As climates change, species can either cope with these changes through evolution, plasticity or by shifting their ranges to track the optimal climatic conditions. Ecological niche modeling (ENM) is a widespread technique in biogeography that estimates the niche of the organism by using occurrences and environmental data to estimate species’ potential distributions. ENMs are often criticized for failing to take species’ dispersal abilities into consideration. Here, we attempt to fill this gap by combining ENMs with dispersal and corridor modeling to study the range dynamics of North …
Using The Baryonic Tully–Fisher Relation To Measure Ho, Stacy S. Mcgaugh
Using The Baryonic Tully–Fisher Relation To Measure Ho, Stacy S. Mcgaugh
Faculty Scholarship
We explore the use of the baryonic Tully-Fisher relation (bTFR) as a new distance indicator. Advances in near-IR imaging and stellar population models, plus precise rotation curves, have reduced the scatter in the bTFR such that distance is the dominant source of uncertainty. Using 50 galaxies with accurate distances from Cepheids or the tip magnitude of the red giant branch, we calibrate the bTFR on a scale independent of H o . We then apply this calibrated bTFR to 95 independent galaxies from the SPARC sample, using CosmicFlows-3 velocities, to deduce the local value of H o . We find …
Detection Of The Thietane Precursor In The Uva Formation Of The Dna 6-4 Photoadduct, Luis A. Ortiz-Rodríguez, Christian Reichardt, Sean J. Hoehn, Carlos E. Crespo-Hernández
Detection Of The Thietane Precursor In The Uva Formation Of The Dna 6-4 Photoadduct, Luis A. Ortiz-Rodríguez, Christian Reichardt, Sean J. Hoehn, Carlos E. Crespo-Hernández
Faculty Scholarship
Notwithstanding the central biological role of the (6-4) photoadduct in the induction of skin cancer by sunlight, crucial mechanistic details about its formation have evaded characterization despite efforts spanning more than half a century. 4-Thiothymidine (4tT) has been widely used as an important model system to study its mechanism of formation, but the excited-state precursor, the intermediate species, and the time scale leading to the formation of the (6-4) photoadduct have remained elusive. Herein, steady-state and time-resolved spectroscopic techniques are combined with new and reported quantum-chemical calculations to demonstrate the excited state leading to the formation of the thietane intermediate, …
Nmr Relaxometry And Diffusometry Analysis Of Dynamics In Ionic Liquids And Ionogels For Use In Lithium-Ion Batteries, Carla C. Fraenza
Nmr Relaxometry And Diffusometry Analysis Of Dynamics In Ionic Liquids And Ionogels For Use In Lithium-Ion Batteries, Carla C. Fraenza
Faculty Scholarship
We have investigated the charge transport dynamics of a novel solid-like electrolyte material based on mixtures of the ionic liquid (IL) 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([BMIM] TFSI) and various concentrations of lithium salt bis(trifluoromethylsulfonyl)imide (LiTFSI) confined within a SiO2 matrix, prepared via a sol-gel method. The translational diffusion coefficients of BMIM+, TFSI‾, and Li+ in ILs and confined ILs (ionogels, IGs) with different concentrations of lithium salt have been measured at variable temperatures, covering the 20-100 °C range, using nuclear magnetic resonance (NMR) pulsed field gradient diffusion spectroscopy. The mobility of BMIM+, TFSI‾, and Li+ was found to increase with the [BMIM] …
Whole Blood Viscosity And Red Blood Cell Adhesion: Potential Biomarkers For Targeted And Curative Therapies In Sickle Cell Disease, Erdem Kucukal, Yuncheng Man, Ailis Hill, Shichen Liu, Allison Bode, Ran An, Jaikrishnan Kadambi, Jane A. Little, Umut A. Gurkan
Whole Blood Viscosity And Red Blood Cell Adhesion: Potential Biomarkers For Targeted And Curative Therapies In Sickle Cell Disease, Erdem Kucukal, Yuncheng Man, Ailis Hill, Shichen Liu, Allison Bode, Ran An, Jaikrishnan Kadambi, Jane A. Little, Umut A. Gurkan
Faculty Scholarship
Sickle cell disease (SCD) is a recessive genetic blood disorder exhibiting abnormal blood rheology. Polymerization of sickle hemoglobin, due to a point mutation in the β-globin gene of hemoglobin, results in aberrantly adhesive and stiff red blood cells (RBCs). Hemolysis, abnormal RBC adhesion, and abnormal blood rheology together impair endothelial health in people with SCD, which leads to cumulative systemic complications. Here, we describe a microfluidic assay combined with a micro particle image velocimetry technique for the integrated in vitro assessment of whole blood viscosity (WBV) and RBC adhesion. We examined WBV and RBC adhesion to laminin (LN) in microscale …
Racial And Ethnic Comparison Of Ecological Risk Factors And Youth Outcomes: A Test Of The Desensitization Hypothesis, Dexter R. Voisin
Racial And Ethnic Comparison Of Ecological Risk Factors And Youth Outcomes: A Test Of The Desensitization Hypothesis, Dexter R. Voisin
Faculty Scholarship
Minority youth, because of structural, ecological, and societal inequalities, are at heightened risk of reporting depression and experiencing negative sanctions associated with delinquency. Sociological theories suggest that greater exposure to ecological risk factors at the peer, family, school and community levels are associated with elevated rates of youth depression and delinquency. Desensitization theory posits that repeated exposures to ongoing stressors result in a numbing of psychological and behavioral responses. Thus, it remains unclear whether racial/ethnic differences exist with regards to how contextual stressors correlate with depression and delinquency. Using a sample of 616 Black, 687 Latinx, and 1,318 White youth, …
Antipsychotic Treatment Experiences Of People With Bipolar I Disorder: Patient Perspectives From An Online Survey, Martha Sajatovic
Antipsychotic Treatment Experiences Of People With Bipolar I Disorder: Patient Perspectives From An Online Survey, Martha Sajatovic
Faculty Scholarship
Background: Oral antipsychotic (AP) medications are frequently prescribed to people with bipolar I disorder (BD-I). A cross-sectional online survey examined the experiences of people living with BD-I with a history of recent AP use. Methods: Adults with self-reported physician-diagnosed BD-I (N = 200) who received oral APs during the prior year completed a survey on AP-related experiences, including side effects and their perceived burden on social functioning, adherence, and work. Items also assessed preferences for trade-offs (balancing symptom management and side effects) when considering a hypothetical new AP. The perceived impact of specific, prevalent side effects on adherence, work, and …