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Quilting As Reproductive Justice Information Activism, Liz Chenevey Sep 2025

Quilting As Reproductive Justice Information Activism, Liz Chenevey

Faculty Scholarship

No abstract provided.


From Displacement To Design: Reframing Work, Skills, And Education For The Ai-Transformed Economy A Review, James Hutson Sep 2025

From Displacement To Design: Reframing Work, Skills, And Education For The Ai-Transformed Economy A Review, James Hutson

Faculty Scholarship

Between 2023 and 2025, the U.S. labor market entered a period of accelerated restructuring driven by generative artificial intelligence (AI) and automation. Routine, entry-level cognitive roles—particularly in clerical, customer service, and junior technical positions—contracted sharply as intelligent systems assumed high-volume, rules-based tasks. While these displacements echo past automation cycles, the present transformation is distinct in its scope, affecting both knowledge work and creative functions, and in its speed, amplified by enterprise-scale adoption. Simultaneously, demand has surged for specialized AI-related positions, interdisciplinary roles blending domain expertise with AI fluency, and ―durable skills‖ that remain resistant to automation. Drawing on labor market …


Bank Supervision And Article Ii, Kathryn Judge Sep 2025

Bank Supervision And Article Ii, Kathryn Judge

Faculty Scholarship

The administrative state is again at a cross roads. The Supreme Court seems poised to continue its march toward trying to fit all of government neatly into one of the three constitutionally enumerated branches. An important front of this shift has been a flattening of the mechanisms through which officers of the United States may be held appropriately accountable for their actions. Waning are the days when Congress had the flexibility to create the institutions it believed were “necessary and proper” for carrying into execution important policy aims and to determine the appropriate mechanisms for accountability in conjunction with considering …


Joinder, Not Jurisdiction: Toward A New Theory Of Standing, Adam N. Steinman Sep 2025

Joinder, Not Jurisdiction: Toward A New Theory Of Standing, Adam N. Steinman

Faculty Scholarship

This Article builds on an important development in the Supreme Court’s standing jurisprudence to propose a novel theory that would allow more meaningful access to federal courts while vindicating legitimate separation-of-powers concerns. In its recent decision in TransUnion LLC v. Ramirez, the Supreme Court endorsed a theory of standing based on Article II, writing that litigation between private parties—even when explicitly authorized by Congress—can run afoul of the executive branch’s interest in “how to prioritize and how aggressively to pursue legal actions against defendants who violate the law.” This Article II move has been justifiably criticized. But it is …


Trump Epa’S Proposed Revocation Of Greenhouse Gas Endangerment Finding Raises Tangle Of Legal Issues, Michael B. Gerrard Sep 2025

Trump Epa’S Proposed Revocation Of Greenhouse Gas Endangerment Finding Raises Tangle Of Legal Issues, Michael B. Gerrard

Faculty Scholarship

On July 29, 2025, at an auto dealership in Indiana, Lee Zeldin, Administrator of the U.S. Environmental Protection Agency (EPA), announced a proposal to withdraw the Endangerment Finding for greenhouse gases (GHGs), which has been EPA’s legal basis for using the Clean Air Act to fight climate change. This action, which will surely be fought in court once it becomes final, raises a host of legal issues. This article discusses the legal basis for and significance of the Endangerment Finding; Zeldin’s principal arguments for revoking it, and challenges that will be raised to them; the range of possible outcomes in …


Algorithmic Governance And The Boardroom: Empirical And Strategic Perspectives On Ai Integration In Corporate And Educational Oversight, James Hutson, Guarango Banerjee Sep 2025

Algorithmic Governance And The Boardroom: Empirical And Strategic Perspectives On Ai Integration In Corporate And Educational Oversight, James Hutson, Guarango Banerjee

Faculty Scholarship

The accelerating digitization of executive decision-making has prompted critical re-examination of the function and value of traditional boards of directors within corporate and educational institutions. Empirical research consistently reveals that human boards, while ostensibly tasked with strategic insight and fiduciary oversight, are frequently constrained by structural inefficiencies—such as director overcommitment, inflated compensation, and persistent conflicts of interest—that undermine organizational performance. Against this backdrop, the integration of Artificial Intelligence agents, either as analytic adjuncts or autonomous decision-makers, emerges as a plausible avenue for enhancing board effectiveness. This article synthesizes global case studies, peer-reviewed findings, and real-time technological developments to critically evaluate …


Stakeholder Views On Lessons Learned For The Antimicrobial Resistance Panel From Previous International Science Panels [Version 1], Iruka N. Okeke, Ayodele A. Akinyele, Javier Guzman, Kevin Outterson Sep 2025

Stakeholder Views On Lessons Learned For The Antimicrobial Resistance Panel From Previous International Science Panels [Version 1], Iruka N. Okeke, Ayodele A. Akinyele, Javier Guzman, Kevin Outterson

Faculty Scholarship

The United Nations General Assembly called in September 2024 for the establishment of an independent panel for actionable evidence against antimicrobial resistance (IPEA). The task of designing the panel was given to the Quadripartite Joint Secretariat (QJS) on Antimicrobial Resistance (AMR) with a delivery timeline of 15 months. To promote stakeholder thought and input around what this panel should look like and how it should work, which could feed into the QJS’s consultation process, we independently commissioned seven papers to examine lessons that could be learned from other high-level scientific panels. We then called a convening of stakeholders that were …


Mitigating Firearm Suicide With Trusted Messengers In Health Care, Michael Ulrich, Cassandra Devaney Sep 2025

Mitigating Firearm Suicide With Trusted Messengers In Health Care, Michael Ulrich, Cassandra Devaney

Faculty Scholarship

Voluntary firearm safety actions avoid Second Amendment scrutiny, but rely on individuals recognizing their own risks. This could be aided by a network of healthcare professionals that have received proper training and information about all available tools to help prevent firearm-related suicide attempts, and combining the trust of clinicians and firearm owners could represent an opportunity to inform and educate in a manner that will engage patients.


Organizing For Abolition In Ice Custody, Sarah R. Sherman-Stokes Sep 2025

Organizing For Abolition In Ice Custody, Sarah R. Sherman-Stokes

Faculty Scholarship

The final Immigration and Customs Enforcement (“ICE”) detainees were released from the Irwin County Detention Center in early September 2021.2 A court did not order the end of ICE detention at Irwin. A social movement, led by people detained at Irwin, had a pronounced impact on the epistemological landscape and changed both normative principles and public opinion.3 Those detained at Irwin organized and acted to create new understanding of law and protect their rights in ways that courts and legislatures could not. This Essay tells the story of that demosprudential project; a dialectic between legal elites and people …


Harnessing The Electronic Health Record To Identify And Enroll People With Epilepsy Into A Self-Management Program: Implementation And Scalability In A Clinical Setting, Clara Adeniyi, Richard Barigye, Jessica Black, Nicole Fiorelli, Carrie Rogers, Martha Sajatovic Sep 2025

Harnessing The Electronic Health Record To Identify And Enroll People With Epilepsy Into A Self-Management Program: Implementation And Scalability In A Clinical Setting, Clara Adeniyi, Richard Barigye, Jessica Black, Nicole Fiorelli, Carrie Rogers, Martha Sajatovic

Faculty Scholarship

Rationale: “Self-management for people with epilepsy and a history of negative health events” (SMART) is an 8-week, remotely delivered, Epilepsy Self-Management (ESM) program. The ongoing EXPANDing self-management support in healthcare networks (EXPAND) initiative leveraged the Electronic Health Record (EHR) to identify SMART candidates, simplify recruitment, and reduce staff workload. Methods: This is an ongoing implementation effort at two Level 4 Epilepsy Centers (Iowa and Cincinnati) using the Epic EHR which follows 9326 People With Epilepsy (PWE). The EHR uses pre-visit screening to identify PWE with a recent seizure; barriers to medication adherence; depression symptoms; age 18–25; or residence in rural …


Social Cognition As A Mediator Between Neurocognition And Functional Outcome In Early Course Schizophrenia, Anju Kotwani, Jessica A. Wojtalik, Douglas D. Gunzler, Wilson J. Brown, Rochanne L. Honarvar, Martha Sajatovic Sep 2025

Social Cognition As A Mediator Between Neurocognition And Functional Outcome In Early Course Schizophrenia, Anju Kotwani, Jessica A. Wojtalik, Douglas D. Gunzler, Wilson J. Brown, Rochanne L. Honarvar, Martha Sajatovic

Faculty Scholarship

Social cognition is an established mediator between neurocognition and functional outcome in schizophrenia, but there is limited evidence for this model specifically in the early course, which is a critical window for intervention to reduce long-term disability. This study aimed to test the social cognition mediator model in the early course of schizophrenia and identify social cognitive subdomains that may have stronger indirect effects on the relationship between neurocognition and functional outcome. This secondary analysis utilized baseline cognitive and functional outcome data from a cognitive remediation trial for outpatients with early course schizophrenia (N = 102). A path analysis approach …


Patterns And Implications Of Missed Injuries On Computed Tomography Imaging In Older Blunt Trauma Patients, Arnav Mahajan, Vanessa P. Ho Sep 2025

Patterns And Implications Of Missed Injuries On Computed Tomography Imaging In Older Blunt Trauma Patients, Arnav Mahajan, Vanessa P. Ho

Faculty Scholarship

Background: Older adults sustain disproportionately morbid injuries from low energy mechanisms, yet guidance around computed tomography imaging is lacking for this demographic. We hypothesize that current imaging practices may lead to potentially missed injuries, increasing morbidity and mortality. Methods: A secondary analysis of a prospective multicenter study (11/2020–12/2021) of older blunt trauma patients was performed. Suboptimal imaging was defined as a mismatch between final injury diagnosis and initial computed tomography imaging. We compared optimally vs not optimally imaged patients to determine factors associated with suboptimal imaging and examined mortality, hospital length of stay, and critical care use with a multivariable …


Social Cognition As A Mediator Between Neurocognition And Functional Outcome In Early Course Schizophrenia, Anju Kotwani, Jessica A. Wojtalik, Douglas D. Gunzler, Wilson J. Brown, Rochanne L. Honarvar, Martha Sajatovic Sep 2025

Social Cognition As A Mediator Between Neurocognition And Functional Outcome In Early Course Schizophrenia, Anju Kotwani, Jessica A. Wojtalik, Douglas D. Gunzler, Wilson J. Brown, Rochanne L. Honarvar, Martha Sajatovic

Faculty Scholarship

Social cognition is an established mediator between neurocognition and functional outcome in schizophrenia, but there is limited evidence for this model specifically in the early course, which is a critical window for intervention to reduce long-term disability. This study aimed to test the social cognition mediator model in the early course of schizophrenia and identify social cognitive subdomains that may have stronger indirect effects on the relationship between neurocognition and functional outcome. This secondary analysis utilized baseline cognitive and functional outcome data from a cognitive remediation trial for outpatients with early course schizophrenia (N = 102). A path analysis approach …


Retinoid Dynamics In Vision: From Visual Cycle Biology To Retina Disease Treatments, Jaclyn Swigris, Made Airanthi K. Widjaja-Adhi, Marcin Golczak Sep 2025

Retinoid Dynamics In Vision: From Visual Cycle Biology To Retina Disease Treatments, Jaclyn Swigris, Made Airanthi K. Widjaja-Adhi, Marcin Golczak

Faculty Scholarship

Light perception is a biological process that facilitates a profound interaction between the external world and the internal functions of living organisms. It begins with the absorption of photons with specialized visual pigments that contain vitamin A-derived chromophores. The light energy triggers the photoisomerization of the visual chromophore, initiating a cascade of signaling events that ultimately convert light into electrical signals interpreted as vision. However, the sustainability of vision relies on the continuous supply of the visual chromophore, which is maintained through light-dependent and light-independent processes. The importance of these processes is underscored by numerous blinding retinal diseases linked to …


Academic Research And (Google Or Reddit): A Librarian-Faculty Collaboration To Improve Student Source Engagement, Stephanie Redekop, Olivia Hobbs Sep 2025

Academic Research And (Google Or Reddit): A Librarian-Faculty Collaboration To Improve Student Source Engagement, Stephanie Redekop, Olivia Hobbs

Faculty Scholarship

Effective source use is a critical skill for first-year writing students because it prepares them for academic, professional, and civic engagement; however, existing research demonstrates that selecting appropriate sources and engaging them insightfully remains a significant challenge. While students struggle with the combined pressures to read, evaluate, and synthesize scholarly sources, we argue that online media including news articles, opinion pieces, and social media posts are a potent but underutilized resource for building students’ competence and confidence with source use. In this article, we present the methods that we have collaboratively developed as an instruction librarian and a first-year writing …


College Students' Perceptions Of Artificial Intelligence (Ai) Risks And Benefits In Pakistan, Rauf Arif, Muhammad Ittefaq, Lamia Zia Aug 2025

College Students' Perceptions Of Artificial Intelligence (Ai) Risks And Benefits In Pakistan, Rauf Arif, Muhammad Ittefaq, Lamia Zia

Faculty Scholarship

With the rapid advancements in technology over the past 2 decades, it has become crucial to understand people’s attitudes toward artificial intelligence (AI) adoption and its associated risks. Given the increasing access to the AI technologies, it is imperative to examine how young people in non-Western societies like Pakistan perceive AI risks and benefits. We conducted an online survey of college students who had used AI technology in the past 6 months. The results of our study indicate that the majority of college students view AI technology positively and perceive it as an opportunity to enhance workplace productivity. In addition, …


Molecular Mechanisms Of Iron Metabolism And Overload, Aditi Tayal, Jasmeen Kaur, Robert W. Maitta Aug 2025

Molecular Mechanisms Of Iron Metabolism And Overload, Aditi Tayal, Jasmeen Kaur, Robert W. Maitta

Faculty Scholarship

Iron represents an essential element required for normal physiologic processes throughout organ systems. A vast network of transporters is involved not only in uptake of this element but in processing, oxidation, and recycling to maintain it in a tight balance to avoid excess storage. This complex network of transporters, including heme and ferroportin, among many others, are responsible for facilitating inter-organ tissue iron exchange and availability, contributing to overall heme homeostasis. However, exposure to high levels of iron can overwhelm compensatory mechanisms that result in its accumulation and toxicity. This is the case of patients with genetic diseases such as …


Barriers And Enablers Of Early Health-Seeking Behaviour Among Women With Preeclampsia And Eclampsia: A Qualitative Study At A National Referral Hospital In Uganda, Shirley Moore, Martha Sajatovic Aug 2025

Barriers And Enablers Of Early Health-Seeking Behaviour Among Women With Preeclampsia And Eclampsia: A Qualitative Study At A National Referral Hospital In Uganda, Shirley Moore, Martha Sajatovic

Faculty Scholarship

Background: Globally, 2–8% of women experience hypertensive disorders in pregnancy (HDPs), including preeclampsia and eclampsia, which are the second leading cause of maternal mortality and morbidity. According to the management protocol for preeclampsia in Uganda, weekly follow-up is recommended for women with preeclampsia without severe features who are below 37weeks of gestation; however, this has not been feasible to most cases of preeclampsia/eclampsia (PE/E). There is still limited information describing barriers and enablers of early health-seeking behaviour amongst women with PE/E, yet this is needed to improve their healthcare. This study explored the barriers and enablers of early health-seeking behaviour …


A 6-Month, Prospective Randomized Controlled Trial Of The Targeted Management (Team) Intervention Vs. Enhanced Treatment As Usual Among Ugandans At Risk For Stroke, Carla Conroy, Joy Yala, Christopher J. Burant, Shirley Moore, Martha Sajatovic Aug 2025

A 6-Month, Prospective Randomized Controlled Trial Of The Targeted Management (Team) Intervention Vs. Enhanced Treatment As Usual Among Ugandans At Risk For Stroke, Carla Conroy, Joy Yala, Christopher J. Burant, Shirley Moore, Martha Sajatovic

Faculty Scholarship

Background Among low and middle-income countries, especially in Sub-Saharan Africa, the stroke burden is severe, with increasing trends in stroke incidence, prevalence, and mortality. Aims This 6-month, prospective randomized controlled trial (RCT) compared a novel stroke risk reduction approach (TargetEd manAgeMent Intervention (TEAM)) vs. Enhanced Treatment as Usual (ETAU) in 247 Ugandans at risk for stroke. Methods Participants, enrolled across 3 Ugandan sites, were adults with high stroke risk. The primary outcome was a change in systolic blood pressure (SBP) from baseline to 6-month follow-up. Secondary outcomes included changes from baseline to 6 months on diastolic BP (DBP), serum lipids, …


Planetary Health: At The Crossroads Of Cvd Prevention, Tasveer Khawaja, Sanjay Rajagopalan Aug 2025

Planetary Health: At The Crossroads Of Cvd Prevention, Tasveer Khawaja, Sanjay Rajagopalan

Faculty Scholarship

Purpose of Review: To highlight important recent findings demonstrating the interconnectedness of planetary and human health with a focus on cardiovascular disease. Recent Findings: Data continue to demonstrate a clear interconnectedness between the health of the planet and human health, with cardiovascular disease as an important outcome. The central roles of air pollution, non-optimal temperatures, water/waste management, and food/biodiversity are highlighted. We also highlight the clear opportunity for healthcare organizations to facilitate change that will yield positive environmental and patient outcomes. Summary: The undeniable interconnectedness of the health of the planet and human health serves as a call to action …


Integrating Neuroaesthetic Design Into Brain-On-Chip Research: Toward Enhanced Neural Engagement And Cognitive Accessibility, Piper Hutson, James Hutson Aug 2025

Integrating Neuroaesthetic Design Into Brain-On-Chip Research: Toward Enhanced Neural Engagement And Cognitive Accessibility, Piper Hutson, James Hutson

Faculty Scholarship

This study examines the potential for neuroaesthetic design and adaptive neurofeedback principles to enhance brain-on-chip (BoC) research, with an emphasis on optimizing neural engagement and cognitive accessibility for diverse populations. Existing BoC platforms have transformed neuroscience through high-fidelity modeling of neural circuits, yet cognitive accessibility and sensory inclusion remain comparatively underexplored. Drawing upon recent studies in neuroinclusion, multisensory interface design, and adaptive feedback, this work synthesizes findings from biophilic interface architecture, neurofeedback literature, and embodied cognition frameworks. The manuscript outlines a multidisciplinary research agenda that prioritizes sensory diversity and ethical considerations in the evolution of BoC systems. Instead of making …


Increasing The Feasibility, Impact, And Equity Of The Medicare Annual Wellness Visit (Awv) With A Practice Tailored Awv Intervention: A Stepped Wedge Clinical Trial Protocol, Chi-Hong Tseng, Neil S. Wenger Aug 2025

Increasing The Feasibility, Impact, And Equity Of The Medicare Annual Wellness Visit (Awv) With A Practice Tailored Awv Intervention: A Stepped Wedge Clinical Trial Protocol, Chi-Hong Tseng, Neil S. Wenger

Faculty Scholarship

Background Older adults vastly underutilize evidence-based preventive health services and screenings that reduce illness, morbidity and mortality. The free-to-patient Medicare Annual Wellness Visit (AWV) is an opportunity to enhance preventive healthcare use, but also is underused. Objectives To evaluate the effect of a practice-tailored intervention on the sustained use of Medicare AWVs and on guideline-recommended preventive services and racial/ethnic disparities in 3 types of practice settings. Methods This is a stepped wedge cluster randomized controlled trial. The intervention will be implemented at the practice level in 24 primary care practices across the country (8 community-based, 8 academic, and 8 serving …


Mitigating Ai Bias With Prompt Augmentation, Verónica C. Gonzales Aug 2025

Mitigating Ai Bias With Prompt Augmentation, Verónica C. Gonzales

Faculty Scholarship

Large-language-model (“LLM”) outputs are inevitably shaped by assumptions, biases, and attitudes rooted in racism and other systemic inequities embedded in the civil-law tradition. This Equity-in-Justice CLE focuses on helping civil legal service providers recognize and work to eliminate biases in generative AI outputs through equity-centered prompt augmentation and engineering. These small, cost-free interventions re-orient LLMs assistance toward fairness, cultural competency, and client-centered outcomes. Participants leave with an action plan for embedding anti-bias safeguards in everyday research, drafting, and client communication tasks.


Cultivating Identity, Workforce Readiness, And Heutagogical Lifelong Learning: The Case For Student-Trained Ai Agents In Postsecondary Education, James Hutson Aug 2025

Cultivating Identity, Workforce Readiness, And Heutagogical Lifelong Learning: The Case For Student-Trained Ai Agents In Postsecondary Education, James Hutson

Faculty Scholarship

The accelerated integration of human-centered artificial intelligence and human-computer intelligent interaction (HCII) into postsecondary education has inaugurated a paradigm shift in how learners develop cognitive, socio emotional, and professional competencies. This article argues that requiring students to iteratively build and refine custom AI agents—digital “clones” or GPTs trained on their evolving beliefs, knowledge, values, and interests addresses three pressing challenges facing contemporary higher education. First, the process of self-modeling via agent training compels deep self-reflection, fostering socio-economic development and identity formation during the critical neurodevelopmental period that extends into the mid-twenties. Second, as industry trends increasingly prioritize the creation of …


Integrating Art Therapy And Emerging Technologies For Enhanced Neuroplasticity And Ptsd Intervention, Piper Hutson, James Hutson Aug 2025

Integrating Art Therapy And Emerging Technologies For Enhanced Neuroplasticity And Ptsd Intervention, Piper Hutson, James Hutson

Faculty Scholarship

Post-traumatic stress disorder (PTSD) remains resistant to many conventional treatments, underscoring the need for integrative approaches that harness neuroplasticity. Art therapy, with its capacity to facilitate nonverbal trauma processing and multisensory engagement, has shown distinctive advantages over verbal and pharmacological interventions. Recent innovations, including virtual reality (VR), artificial intelligence (AI), and biofeedback have amplified the therapeutic efficacy of art-based interventions by enabling adaptive, real-time modulation of emotional and physiological states. This review synthesizes current research on technologically enhanced art therapy, comparing it to established treatments such as cognitive behavioral therapy (CBT) and eye movement desensitization and reprocessing (EMDR). Findings indicate …


Complex Factors Impacting Smoking Behavior In Cancer Survivors With Food Insecurity, Madeline C. Castele, Kareena Shah, Avianna Thompson, Jin E. Kim-Mozeleski Aug 2025

Complex Factors Impacting Smoking Behavior In Cancer Survivors With Food Insecurity, Madeline C. Castele, Kareena Shah, Avianna Thompson, Jin E. Kim-Mozeleski

Faculty Scholarship

Objectives: Tobacco use remains prevalent among people with social needs, such as food insecurity. In this study, we aimed to understand the complex experiences of low-income cancer survivors with food insecurity who smoke tobacco, to identify the unique smoking cessation needs for this group. Methods: We conducted in-depth, semi-structured qualitative interviews with 40 adults experiencing food insecurity who continued smoking after a cancer diagnosis. Interviews focused on smoking behaviors, cessation interest, cancer experiences, and financial circumstances. We analyzed the data using reflexive thematic analysis. Results: In this sample of cancer survivors (50% female, mean age 42 years, 60% black/African American, …


Teaching Transactional Skills And Lawyering Values To First-Year Students Through An Affordable-Housing Deal, Laura E. D'Amato Aug 2025

Teaching Transactional Skills And Lawyering Values To First-Year Students Through An Affordable-Housing Deal, Laura E. D'Amato

Faculty Scholarship

With the anticipated launch of the NextGen bar exam next year, transactional lawyering skills are enjoying increased attention in first-year law school curricular development. At the same time, recent amendments to ABA Rule 303 have made it essential for new law students to learn about the profession’s core values and responsibilities. While these evolving priorities open the door to pedagogical innovation, incorporating two distinct topics into an already packed curriculum can be challenging. This article explores how a simulated affordable-housing financing deal has served as a cohesive foundation for introducing first-year students to transactional skills and core professional values.


Immunosuppressive Formulations For Immunological Defense Against Traumatic Brain Injury, Abhirami Thumsi, Abhinav P. Acharya, Jeffrey Capadona, Sanmoy Pathak, Taravat Khodaei, Madan Mohan Chandra Sekhar Jaggarapu, Abhirami P. Suresh Jul 2025

Immunosuppressive Formulations For Immunological Defense Against Traumatic Brain Injury, Abhirami Thumsi, Abhinav P. Acharya, Jeffrey Capadona, Sanmoy Pathak, Taravat Khodaei, Madan Mohan Chandra Sekhar Jaggarapu, Abhirami P. Suresh

Faculty Scholarship

Traumatic brain injury (TBI) and subsequent neurodegeneration is partially driven by chronic inflammation both locally and systemically. Yet, current clinical intervention strategies do not mitigate inflammation sequelae necessitating the development of innovative approaches to reduce inflammation and minimize deleterious effects of TBI. Herein, a subcutaneous formulation based on polymer of alpha-ketoglutarate (paKG) delivering glycolytic inhibitor PFK15 (PFKFB3 inhibitor, a rate limiting step in glycolysis), alpha-ketoglutarate (to fuel Krebs cycle) and peptide antigen from myelin proteolipid protein (PLP139-151) is utilized as the prophylactic immunosuppressive formulation in a mouse model of TBI. In vitro, the paKG(PFK15+PLP) formulation stimulates proliferation of immunosuppressive regulatory …


Polylactic Acid (Pla)-Based Multifunctional And Biodegradable Nanocomposites And Their Applications, Md Shariful Islam, G. M. Fazley Elahee, Xiong (Bill) Yu, Rigoberto Castillo Advincula, Changyong (Chase) Cao Jul 2025

Polylactic Acid (Pla)-Based Multifunctional And Biodegradable Nanocomposites And Their Applications, Md Shariful Islam, G. M. Fazley Elahee, Xiong (Bill) Yu, Rigoberto Castillo Advincula, Changyong (Chase) Cao

Faculty Scholarship

Polylactic acid (PLA)-based nanocomposites are emerging as multifunctional, biodegradable materials, offering sustainable alternatives to petroleum-based plastics. This review examines recent advancements in PLA nanocomposites, focusing on enhanced mechanical strength, thermal stability, and biodegradability achieved through nanofillers like metallic particles, carbon-based materials, and ceramics. Techniques such as in situ polymerization, melt mixing, and electrospinning enable application-specific improvements. PLA's limitations, including brittleness and low barrier properties, are addressed to support diverse applications: in packaging (e.g., extended shelf life), biomedicine (e.g., degradable implants), and electronics (e.g., flexible devices). Despite challenges with filler dispersion and thermal resistance, continued innovations expand PLA's potential across multiple …


Family Caregivers’ Perceptions Of Quality Of Dementia Self-Care In Wakiso District, Uganda, Martha Sajatovic, Kylie Meyer Jul 2025

Family Caregivers’ Perceptions Of Quality Of Dementia Self-Care In Wakiso District, Uganda, Martha Sajatovic, Kylie Meyer

Faculty Scholarship

INTRODUCTION: In Sub-Saharan Africa, most people with dementia are cared for in the home setting (dementia self-care) with hardly any support from the formal health and social care system. The study explored family caregivers' perceptions of quality of dementia self-care. METHODS: A descriptive-exploratory qualitative study design was used. Data were collected through four focus group discussions with 48 family caregivers of older people with dementia, recruited from four villages of the Wakiso district in Uganda. RESULTS: Five themes emerged: (1) patience and understanding; (2) maintaining hygiene and cleanliness; (3) constant supervision and safety precautions; (4) personalized care by understanding individual …