Digital Commons Network^™

Knowledge-Driven Interpretative Conditional Diffusion Model For Contrast-Free Myocardial Infarction Enhancement Synthesis, Shuo Li

Faculty Scholarship

Synthesis of myocardial infarction enhancement (MIE) images without contrast agents (CAs) has shown great potential to advance myocardial infarction (MI) diagnosis and treatment. It provides results comparable to late gadolinium enhancement (LGE) images, thereby reducing the risks associated with CAs and streamlining clinical workflows. The existing knowledge-and-data-driven approach has made progress in addressing the complex challenges of synthesizing MIE images (i.e., invisible myocardial scars and high inter-individual variability) but still has limitations in the interpretability of kinematic inference, morphological knowledge integration, and kinematic-morphological fusion, thereby reducing the transparency and reliability of the model and causing information loss during synthesis. In …

Reasoning From Injustice, Robert L. Tsai

Faculty Scholarship

In a series of lectures at Yale Law School, the Harvard political theorist Judith Shklar critiqued leading models of justice as overly abstract and lacking a realistic account of the social dynamics that perpetuate injustice. In this essay, Professor Tsai builds on Shklar’s account of injustice as a social phenomenon by offering a structural reading of key literary texts that explore the nature of legal injustice—from the Book of Job to Harriett Beecher Stowe’s Uncle Tom’s Cabin and Frederick Douglass’s The Heroic Slave. A close reading of these texts permits us to flesh out Shklar’s observations and “give injustice …

Benchmarking Age-Gates, Katharine B. Silbaugh

Faculty Scholarship

This article examines how legal actors—particularly legislators, judges, and attorneys—invoke chronological age to justify the application of legal rules to adolescents. In doing so, they often rely on comparisons to existing “age-gates,” treating these thresholds (such as ages 18 or 21) as self-justifying reference points. Age 18, marking the legal transition from childhood to adulthood, and age 21, the former age of majority and current sales age for certain controlled substances, serve as especially powerful rhetorical anchors in age-based legal reasoning. These anchor points shape how legal actors advocate for or against particular age thresholds, often substituting analogy for substantive …

Performance Leads Governance: A Comment On Professor Tallarita’S Dual-Class Analysis, David J. Berger, Pierluigi Matera

Faculty Scholarship

The rise of dual-class stock structures in corporate governance has sparked intense academic, legal, and regulatory debate. In his recent contribution, Dual-Class Contracting, Professor Tallarita persuasively challenges some contemporary interpretations of contractarian theories by showing that dual-class structures do not reflect bespoke bargaining or firm-specific negotiation, but rather result from lawyer-driven standardization, social norms, and path dependency.

Drawing on Tallarita’s empirical findings, we argue that the reality of dual-class structures extends beyond governance formality. Specifically, we contend that investor behavior is driven not by structural governance ideals, but by corporate performance and mission alignment. Companies increasingly design governance structures based …

Measuring And Mitigating Drip Pricing Overcharge: Evidence From An Online Marketplace Experiment With A Digital Shopping Assistant, Benjamin Lu, Daniel Markovits, Andrew Miller, Rory Van Loo

Faculty Scholarship

We study how much drip pricing (hidden mandatory fees revealed after consumers have begun the buying process) raises prices paid for identical goods and whether an automated shopping assistant mitigates the effect. In a randomized online marketplace experiment (n = 1608) with real purchases of gift cards funded by a $15 endowment, we vary the initial and final presentation of the gift cards’ prices across 33 levels and randomly assign participants to an automated assistant that flags a lower-price identical option and links to it. Relative to transparent pricing, drip pricing increases the average price paid by up to a …

Criminal Court's Disability, Zohra Ahmed

Faculty Scholarship

Do criminal courts meaningfully accommodate psychiatric disability? A review of competency proceedings across the United States suggests not. In competency to stand trial proceedings, criminal court actors offer a narrow vision of psychiatric disability that excludes many defendants. Ultimately, the institutional context of criminal court undermines even the meagre accommodations that the competency framework provides.

Competency proceedings are the constitutional accommodations available to disabled defendants if they can establish that they are unable to consult with their lawyers or if they do not have a rational or factual understanding of the proceedings against them. After a finding of incompetency, the …

De Minimis Copying: An Empirical Study, Jessica Silbey, Samantha Zyontz

Faculty Scholarship

In the internet age, the copyright de minimis defense has increased in relevance as copyright lawsuits (and IP generally) are more mainstream and infringement liability more widespread. This Article is the first empirical analysis of copyright de minimis defense cases, collecting and analyzing all such decisions since the mid-19th century. It traces the doctrine’s development over the past century and its evolution in the digital era, when copying has become even more ubiquitous but its triviality remains widely disputed. The Article’s aim is not only to map the de minimis defense to learn more about it doctrinally—asking when is copying …

Near Real-Time Monitoring Reveals Extensive Recent Forest Disturbance In Ghana’S Protected Areas, Luofan Dong, Xiaojing Tang, Foster Mensah, Bashara Ahmed Abubakari, Kelsee H. Bratley, Pontus Olofsson, Curtis E. Woodcock

Faculty Scholarship

The Protected Areas (PAs) in Ghana play a critical role in preserving the abundant biodiversity of the West Africa Green Belt. But recent changes in policies and regulations have facilitated logging and mining activities, which have accelerated forest disturbances. While there is a consensus that PAs are undergoing destructive change, the extent, rate, and locations of forest disturbances are undocumented. In this study, we applied the fusion near real-time (FNRT) algorithm that utilizes Landsat, Sentinel-1, and Sentinel-2 data and sampling to monitor forests in the PAs of Ghana. The results reveal that 704.74 (±177.24) km2 of forest in the PAs …

Peripheral Calcifying Odontogenic Cyst In Maxillary Anterior Gingiva: A Case Report, Dimitris N. Tatakis

Faculty Scholarship

BACKGROUND: Calcifying odontogenic cysts (Gorlin cysts) most commonly present centrally and have only rarely been reported in peripheral locations. The purpose of this report is to describe a new case of peripheral calcifying odontogenic cyst (PCOC) occurring in the anterior maxillary gingiva and to review the management and differential diagnosis of such a lesion. METHODS: A 37-year-old female presented with a long-standing submucosal nodule on the gingiva between the maxillary central incisors, with asymptomatic growth over the last three years. Following an initial incisional biopsy, a diagnosis of PCOC was established. To exclude the possibility of a central process, a …

Enhanced Prediction Of Condensation Pressure Drop In Mini And Microchannels Using Physics-Assisted Machine Learning, Farshad Barghi Golezani, Jiayuan Li, Forouzan Naderi, Alexander Meylikhov, Logan M. Pirnstill, Issam Mudawar, Chirag R. Kharangate

Faculty Scholarship

Reliable prediction of frictional pressure drop during condensation in mini‑ and microchannels underpins both thermal management effectiveness and overall heat transfer performance in compact two‑phase heat exchangers, cold‑plates, and on‑chip cooling loops. Excess pressure loss burdens pumps, raises electrical consumption, and can destabilize flow, whereas under‑prediction risks temperature overshoot and premature dryout. Conventional empirical correlations and flexible machine-learning models can lose accuracy once channel size, working fluid, or operating conditions stray beyond their testing range. This study uses a physics‑assisted machine‑learning framework that overlays an XGBoost residual learner on the Kim–Mudawar separated‑flow correlation to achieve high fidelity and robustness in …

Reconceptualizing Metadata Management As A Design Discipline, Rebecca B. French

Faculty Scholarship

Libraries are increasingly exploring design approaches, but their utility has been overlooked in the area of metadata management. This article argues that metadata management should be considered a design discipline. Key elements of design epistemology and their relevance to cataloging and metadata work are explored through a case study of developing a workflow to update OCLC numbers in a library catalog. Conceptualizing metadata management through the lens of design provides a new view of the field that expands possibilities for education, advocacy, research, and practice.

Cognition, White Matter Hyperintensities And Suicide Risk In Late-Life Depression Patients: An Exploratory Study, Martha Sajatovic

Faculty Scholarship

Objective: Suicide among older adults represents a major public health concern and is closely associated with late-life depression (LLD). White matter hyperintensities (WMHs), frequently observed in the aging population, have been linked to both LLD and cognitive impairment. However, the role of WMH burden and cognitive dysfunction in older adults with LLD who have recently attempted suicide remains unclear. This study aims to investigate differences in WMH burden and cognitive performance across three groups: LLD patients with a recent suicide attempt (recent suicide attempt group, RSA), non-suicidal LLD patients (non-suicidal group, NS), and healthy older adults (healthy comparison group, HC). …

Psma-1-Dota Potentially For Effective Targeted Radioligand Therapy Of Prostate Cancer, Xinning Wang, Olga Sergeeva, Maxim Sergeev, Lifang Zhang, Zoey Lockwood, Zhenghong Lee, James P. Basilion

Faculty Scholarship

Purpose: While PSMA-targeted radioligand therapy (RLT) has shown remarkable efficacy for treating end-stage prostate cancer, the α-emitting RLT often results in severe salivary gland toxicity, limiting its use. Various strategies to mitigate this side effect have been attempted with limited success. Accordingly, this study introduced a new PSMA-targeting ligand with more favorable binding characteristics than the existing ligands. Procedures: The binding affinity of PSMA-1-DOTA to PSMA was compared with that of PSMA-11 and PSMA I&T. Comparison of uptake in the salivary glands, kidneys and PC3pip tumor cells in the xenograft mouse models between [⁶⁸Ga]Ga-PSMA-1-DOTA, [⁶⁸Ga]Ga-PSMA-11 and [⁶⁸Ga]Ga-PSMA I&T was conducted …

Toward A Unified Neuroaesthetic Framework For Art-Based Interventions In Substance Use Recovery - A Review, Piper Hutson, James Hutson

Faculty Scholarship

Art-based interventions have gained increasing recognition as complementary strategies for substance use disorder (SUD) recovery and prevention, yet the field remains fragmented across clinical art therapy, community-based programs, and expressive digital practices. This article advances a unified neuroaesthetic framework that integrates sensory regulation, narrative integration, and interpersonal synchronization as the core mechanisms of healing. Drawing on recent U.S.-based empirical studies (post-2020), the paper synthesizes evidence from multiple modalities, including visual arts, music therapy, dance/movement practices, and digital storytelling, each demonstrating measurable effects on craving reduction, stress regulation, identity reconstruction, and social connection. Neuroscientific insights are central: findings highlight how creative …

Gaming As Therapeutic Modality For Military Veterans: Evidence, Mechanisms, And Program Design, Piper Hutson, James Hutson

Faculty Scholarship

This study synthesizes interdisciplinary evidence on game-based interventions for military veterans, mapping neurological mechanisms to clinically relevant outcomes while outlining design principles for community programs that leverage interactive media. The review characterizes how structured gameplay supports emotional regulation through attentional control, predictable feedback schedules, and reward-mediated learning that elevates motivation and mood; links to dopaminergic signaling and reduced rumination suggest plausible pathways for affective stabilization. Executive functions receive targeted engagement via strategy, puzzle, and action mechanics that demand working memory, cognitive flexibility, inhibition, and rapid decision-making, providing ecologically valid practice with measurable transfer to daily functioning. Social architectures in multiplayer …

Premenopausal Transition In Neurodivergent Women With Musculoskeletal Syndromes: Mechanisms, Risks, And Neuroinclusive Therapeutics, Piper Hutson, James Hutson

Faculty Scholarship

Neurodivergent women with chronic musculoskeletal syndromes experience disproportionate premenopausal symptom burdens that are poorly characterized in extant clinical paradigms and practice. The compounded interplay of estrogen fluctuations in premenopause with sensory–executive differences and baseline nociception from joint or connective-tissue pathology yields intensified pain, mood dysregulation, and functional decline. Evidence indicates estrogen modulates nociception, neuroinflammation, bone remodeling, and monoaminergic signaling; premenopausal variability magnifies pain, affective lability, and cognitive drift—effects accentuated in autism and ADHD. Coexisting hypermobility, fibromyalgia, or connective-tissue disorders compromise joint integrity and proprioception, increasing susceptibility to estrogen-dependent changes in bone microarchitecture and tendon homeostasis. This article advances an integrative …

Joinder, Not Jurisdiction: Toward A New Theory Of Standing, Adam N. Steinman

Faculty Scholarship

This Article builds on an important development in the Supreme Court’s standing jurisprudence to propose a novel theory that would allow more meaningful access to federal courts while vindicating legitimate separation-of-powers concerns. In its recent decision in TransUnion LLC v. Ramirez, the Supreme Court endorsed a theory of standing based on Article II, writing that litigation between private parties—even when explicitly authorized by Congress—can run afoul of the executive branch’s interest in “how to prioritize and how aggressively to pursue legal actions against defendants who violate the law.” This Article II move has been justifiably criticized. But it is …

From Displacement To Design: Reframing Work, Skills, And Education For The Ai-Transformed Economy A Review, James Hutson

Faculty Scholarship

Between 2023 and 2025, the U.S. labor market entered a period of accelerated restructuring driven by generative artificial intelligence (AI) and automation. Routine, entry-level cognitive roles—particularly in clerical, customer service, and junior technical positions—contracted sharply as intelligent systems assumed high-volume, rules-based tasks. While these displacements echo past automation cycles, the present transformation is distinct in its scope, affecting both knowledge work and creative functions, and in its speed, amplified by enterprise-scale adoption. Simultaneously, demand has surged for specialized AI-related positions, interdisciplinary roles blending domain expertise with AI fluency, and ―durable skills‖ that remain resistant to automation. Drawing on labor market …

Most-Favored-Nation's False Promises, George A. Bermann

Faculty Scholarship

Most-favoured-nation (MFN) protection seems decidedly straightforward both in meaning and operation, certainly as compared to other investment protections, such as fair and equitable treatment, which are plagued with indeterminacy. But the clarity of meaning and ease of application of MFN clauses are largely illusory. An examination of arbitral case law reveals seriously underestimated uncertainties surrounding the doctrine’s scope and workings. But the problems with MFN run far deeper. MFN may have the virtue of enhancing the level of protection of foreign investments. But States do not only extend benefits; they also withhold them. MFN disrespects the balance that States sought …

Bank Supervision And Article Ii, Kathryn Judge

Faculty Scholarship

The administrative state is again at a cross roads. The Supreme Court seems poised to continue its march toward trying to fit all of government neatly into one of the three constitutionally enumerated branches. An important front of this shift has been a flattening of the mechanisms through which officers of the United States may be held appropriately accountable for their actions. Waning are the days when Congress had the flexibility to create the institutions it believed were “necessary and proper” for carrying into execution important policy aims and to determine the appropriate mechanisms for accountability in conjunction with considering …

Algorithmic Governance And The Boardroom: Empirical And Strategic Perspectives On Ai Integration In Corporate And Educational Oversight, James Hutson, Guarango Banerjee

Faculty Scholarship

The accelerating digitization of executive decision-making has prompted critical re-examination of the function and value of traditional boards of directors within corporate and educational institutions. Empirical research consistently reveals that human boards, while ostensibly tasked with strategic insight and fiduciary oversight, are frequently constrained by structural inefficiencies—such as director overcommitment, inflated compensation, and persistent conflicts of interest—that undermine organizational performance. Against this backdrop, the integration of Artificial Intelligence agents, either as analytic adjuncts or autonomous decision-makers, emerges as a plausible avenue for enhancing board effectiveness. This article synthesizes global case studies, peer-reviewed findings, and real-time technological developments to critically evaluate …

Harnessing The Electronic Health Record To Identify And Enroll People With Epilepsy Into A Self-Management Program: Implementation And Scalability In A Clinical Setting, Clara Adeniyi, Richard Barigye, Jessica Black, Nicole Fiorelli, Carrie Rogers, Martha Sajatovic

Faculty Scholarship

Rationale: “Self-management for people with epilepsy and a history of negative health events” (SMART) is an 8-week, remotely delivered, Epilepsy Self-Management (ESM) program. The ongoing EXPANDing self-management support in healthcare networks (EXPAND) initiative leveraged the Electronic Health Record (EHR) to identify SMART candidates, simplify recruitment, and reduce staff workload. Methods: This is an ongoing implementation effort at two Level 4 Epilepsy Centers (Iowa and Cincinnati) using the Epic EHR which follows 9326 People With Epilepsy (PWE). The EHR uses pre-visit screening to identify PWE with a recent seizure; barriers to medication adherence; depression symptoms; age 18–25; or residence in rural …

Social Cognition As A Mediator Between Neurocognition And Functional Outcome In Early Course Schizophrenia, Anju Kotwani, Jessica A. Wojtalik, Douglas D. Gunzler, Wilson J. Brown, Rochanne L. Honarvar, Martha Sajatovic

Faculty Scholarship

Social cognition is an established mediator between neurocognition and functional outcome in schizophrenia, but there is limited evidence for this model specifically in the early course, which is a critical window for intervention to reduce long-term disability. This study aimed to test the social cognition mediator model in the early course of schizophrenia and identify social cognitive subdomains that may have stronger indirect effects on the relationship between neurocognition and functional outcome. This secondary analysis utilized baseline cognitive and functional outcome data from a cognitive remediation trial for outpatients with early course schizophrenia (N = 102). A path analysis approach …

Patterns And Implications Of Missed Injuries On Computed Tomography Imaging In Older Blunt Trauma Patients, Arnav Mahajan, Vanessa P. Ho

Faculty Scholarship

Background: Older adults sustain disproportionately morbid injuries from low energy mechanisms, yet guidance around computed tomography imaging is lacking for this demographic. We hypothesize that current imaging practices may lead to potentially missed injuries, increasing morbidity and mortality. Methods: A secondary analysis of a prospective multicenter study (11/2020–12/2021) of older blunt trauma patients was performed. Suboptimal imaging was defined as a mismatch between final injury diagnosis and initial computed tomography imaging. We compared optimally vs not optimally imaged patients to determine factors associated with suboptimal imaging and examined mortality, hospital length of stay, and critical care use with a multivariable …

Social Cognition As A Mediator Between Neurocognition And Functional Outcome In Early Course Schizophrenia, Anju Kotwani, Jessica A. Wojtalik, Douglas D. Gunzler, Wilson J. Brown, Rochanne L. Honarvar, Martha Sajatovic

Faculty Scholarship

Social cognition is an established mediator between neurocognition and functional outcome in schizophrenia, but there is limited evidence for this model specifically in the early course, which is a critical window for intervention to reduce long-term disability. This study aimed to test the social cognition mediator model in the early course of schizophrenia and identify social cognitive subdomains that may have stronger indirect effects on the relationship between neurocognition and functional outcome. This secondary analysis utilized baseline cognitive and functional outcome data from a cognitive remediation trial for outpatients with early course schizophrenia (N = 102). A path analysis approach …

Retinoid Dynamics In Vision: From Visual Cycle Biology To Retina Disease Treatments, Jaclyn Swigris, Made Airanthi K. Widjaja-Adhi, Marcin Golczak

Faculty Scholarship

Light perception is a biological process that facilitates a profound interaction between the external world and the internal functions of living organisms. It begins with the absorption of photons with specialized visual pigments that contain vitamin A-derived chromophores. The light energy triggers the photoisomerization of the visual chromophore, initiating a cascade of signaling events that ultimately convert light into electrical signals interpreted as vision. However, the sustainability of vision relies on the continuous supply of the visual chromophore, which is maintained through light-dependent and light-independent processes. The importance of these processes is underscored by numerous blinding retinal diseases linked to …

Amicus In Trump V. Cook: The Fed, Offices As Property, And The Meaning Of “Cause”, Jed Handelsman Shugerman

Faculty Scholarship

The Federal Reserve Act states that “each member shall hold office for a term of fourteen years from the expiration of the term of his predecessor, unless sooner removed for cause by the President.” 12 U.S.C. § 242. Based on the historical record, when Congress creates an office with a fixed term of years and protects against removal without “cause,” Congress has both granted “a constitutionally protected property interest” under the Fifth Amendment (that cannot be taken away without “due process”) and extended a statutory entitlement to receive fair notice and a meaningful opportunity to respond before any removal may …

Organizing For Abolition In Ice Custody, Sarah R. Sherman-Stokes

Faculty Scholarship

The final Immigration and Customs Enforcement (“ICE”) detainees were released from the Irwin County Detention Center in early September 2021.² A court did not order the end of ICE detention at Irwin. A social movement, led by people detained at Irwin, had a pronounced impact on the epistemological landscape and changed both normative principles and public opinion.³ Those detained at Irwin organized and acted to create new understanding of law and protect their rights in ways that courts and legislatures could not. This Essay tells the story of that demosprudential project; a dialectic between legal elites and people …

Planetary Health: At The Crossroads Of Cvd Prevention, Tasveer Khawaja, Sanjay Rajagopalan

Faculty Scholarship

Purpose of Review: To highlight important recent findings demonstrating the interconnectedness of planetary and human health with a focus on cardiovascular disease. Recent Findings: Data continue to demonstrate a clear interconnectedness between the health of the planet and human health, with cardiovascular disease as an important outcome. The central roles of air pollution, non-optimal temperatures, water/waste management, and food/biodiversity are highlighted. We also highlight the clear opportunity for healthcare organizations to facilitate change that will yield positive environmental and patient outcomes. Summary: The undeniable interconnectedness of the health of the planet and human health serves as a call to action …

Integrating Neuroaesthetic Design Into Brain-On-Chip Research: Toward Enhanced Neural Engagement And Cognitive Accessibility, Piper Hutson, James Hutson

Faculty Scholarship

This study examines the potential for neuroaesthetic design and adaptive neurofeedback principles to enhance brain-on-chip (BoC) research, with an emphasis on optimizing neural engagement and cognitive accessibility for diverse populations. Existing BoC platforms have transformed neuroscience through high-fidelity modeling of neural circuits, yet cognitive accessibility and sensory inclusion remain comparatively underexplored. Drawing upon recent studies in neuroinclusion, multisensory interface design, and adaptive feedback, this work synthesizes findings from biophilic interface architecture, neurofeedback literature, and embodied cognition frameworks. The manuscript outlines a multidisciplinary research agenda that prioritizes sensory diversity and ethical considerations in the evolution of BoC systems. Instead of making …