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Articles 1141 - 1170 of 10621
Full-Text Articles in Entire DC Network
Increased Cytokine Gene Expression And Cognition Risk Associated With Androgen Deprivation Therapy, Shiv Verma, Prem Prakash Kushwaha, Eswar Shankar, Lee E. Ponsky, Sanjay Gupta
Increased Cytokine Gene Expression And Cognition Risk Associated With Androgen Deprivation Therapy, Shiv Verma, Prem Prakash Kushwaha, Eswar Shankar, Lee E. Ponsky, Sanjay Gupta
Faculty Scholarship
Background: Androgen deprivation therapy (ADT) is a standard treatment modality for locally advanced, high-risk, and metastatic hormone-sensitive prostate cancer. Long-term ADT treatment likely develops side-effects that include changes in cognition or onset of dementia. However, the molecular understanding of this effect remains elusive. We attempt to establish a link between ADT and changes in cognitive function using patient databases and bioinformatics analyses. Methods: Gene expression profiling was performed using RNA sequencing data from Alzheimer patient cohort and compared with the data from advanced-stage prostate cancer patients receiving neoadjuvant antiandrogen therapy. Differentially expressed genes (DEGs) were analyzed using the Ingenuity knowledge …
No-One Receives Psychiatric Treatment In A Squad Car, Judy A. Clausen, Joanmarie Davoli
No-One Receives Psychiatric Treatment In A Squad Car, Judy A. Clausen, Joanmarie Davoli
Faculty Scholarship
No abstract provided.
The Political Urgency Of Black Manhood: Frederick Douglass On Constitutional Theory, John M. Kang
The Political Urgency Of Black Manhood: Frederick Douglass On Constitutional Theory, John M. Kang
Faculty Scholarship
How did Frederick Douglass—one who was born a slave, one who had been denied all formal education, one who had been sundered from his family, one who had been starved, tortured, and, on occasion, nearly killed—manage to muster the courage to do something as bold as challenge the United States Supreme Court? This Article suggests that Douglass, in order to assert his right as an American citizen, first had to assert his right as a man in an explicitly gendered sense. That is, Douglass had to muster a powerful sense of manliness that could elevate him psychologically to assert his …
Forecasting The How And Why Of Corporate Crime's Demise, Miriam H. Baer
Forecasting The How And Why Of Corporate Crime's Demise, Miriam H. Baer
Faculty Scholarship
No abstract provided.
Defense Counsel's Cross Purposes: Prior Conviction Impeachment Of Prosecution Witnesses, Anna Roberts
Defense Counsel's Cross Purposes: Prior Conviction Impeachment Of Prosecution Witnesses, Anna Roberts
Faculty Scholarship
No abstract provided.
Can You Be A Legal Ethics Scholar And Have Guts?, Cynthia Godsoe, Abbe Smith, Ellen Yaroshefsky
Can You Be A Legal Ethics Scholar And Have Guts?, Cynthia Godsoe, Abbe Smith, Ellen Yaroshefsky
Faculty Scholarship
No abstract provided.
What’S (Race In) The Law Got To Do With It: Incorporating Race In Legal Curriculum, Sonia Gipson Rankin
What’S (Race In) The Law Got To Do With It: Incorporating Race In Legal Curriculum, Sonia Gipson Rankin
Faculty Scholarship
Gen Z is defined as including persons born after 1996 and, in 2018, the first Gen Z would have been twenty-two years old, the historically traditional age that many complete undergraduate studies and enter law school. With Gen Z entering law schools, the legal academy has been wholeheartedly preparing for the arrival of the first truly digital native generation in a myriad of ways. However, law training has been slow to progress in addressing the unspoken complexities of context and unconscious bias in the classroom with this population. Today’s Gen Z students were predominately raised in de facto segregated schools …
The Crt Of Black Lives Matter, Angela Onwuachi-Willig
The Crt Of Black Lives Matter, Angela Onwuachi-Willig
Faculty Scholarship
Critical Race Theory ("CR T"), or at least its principles, stands at the core of most prominent social movements of today-from the resurgence of the #MeToo Movement, which was founded by a Black woman, Tarana Burke, to the Black Lives Matter Movement, which was founded by three Black women: Opal Tometi, Alicia Garza, and Patrisse Cullors. In fact, Critical Race Theorists have long defined CRT itself as a movement, one that has not only provided theoretical interventions regarding the relationship between race, racism, power, and the law, but that has also encouraged and, in fact, inspired and guided social movements. …
Jd-Next: A Randomized Experiment Of An Online Scalable Program To Prepare Diverse Students For Law School, Katherine Cheng, Jessica Findley, Adriana Cimetta, Heidi Burross, Matt Charles, Cayley Balser, Ran Li, Christopher Robertson
Jd-Next: A Randomized Experiment Of An Online Scalable Program To Prepare Diverse Students For Law School, Katherine Cheng, Jessica Findley, Adriana Cimetta, Heidi Burross, Matt Charles, Cayley Balser, Ran Li, Christopher Robertson
Faculty Scholarship
As one of two companion papers, this article explains our efforts to create and evaluate a program called JD-Next, which exposed students to legal education, prepared them to succeed, and assessed their ability to do so. JD-Next is a fully online, noncredit, seven-and-a-half-week course to train potential JD students in case reading and analysis skills before their first year of law school. This article focuses on rigorously testing the exposure and preparation functions of this program in 2019 to determine whether participation in such a course can improve law school confidence and performance of matriculating students. In the companion article, …
Using Mhealth To Improve Adherence And Reduce Blood Pressure In Individuals With Hypertension And Bipolar Disorder (Itab-Cv): Study Protocol For A 2-Stage Randomized Clinical Trial, Jennifer B. Levin, Farren Briggs, Mahboob Rahman, Kurt C. Stange, Douglas Einstadter, Celeste Weise, Carla Conroy, Joy Yala, Ethan Radatz, Martha Sajatovic
Using Mhealth To Improve Adherence And Reduce Blood Pressure In Individuals With Hypertension And Bipolar Disorder (Itab-Cv): Study Protocol For A 2-Stage Randomized Clinical Trial, Jennifer B. Levin, Farren Briggs, Mahboob Rahman, Kurt C. Stange, Douglas Einstadter, Celeste Weise, Carla Conroy, Joy Yala, Ethan Radatz, Martha Sajatovic
Faculty Scholarship
Background: Cardiovascular disease in individuals with mental health conditions such as bipolar disorder is highly prevalent and often poorly managed. Individuals with bipolar disorder face significant medication adherence barriers, especially when they are prescribed multiple medications for other health conditions including hypertension. Poor adherence puts them at a disproportionate risk for poor health outcomes. As such, there is a need for effective interventions to improve hypertension medication adherence, particularly in patients that struggle with adherence due to mental health comorbidity. Methods: This 5-year project uses a 2-stage randomized controlled trial design to evaluate a brief, practical adherence intervention delivered via …
Using Mhealth To Improve Adherence And Reduce Blood Pressure In Individuals With Hypertension And Bipolar Disorder (Itab-Cv): Study Protocol For A 2-Stage Randomized Clinical Trial, Jennifer B. Levin, Farren Briggs, Mahboob Rahman, Kurt Stange, Douglas Einstadter, Celeste Weise, Carla Conroy, Joy Yala, Ethan Radatz, Martha Sajatovic
Using Mhealth To Improve Adherence And Reduce Blood Pressure In Individuals With Hypertension And Bipolar Disorder (Itab-Cv): Study Protocol For A 2-Stage Randomized Clinical Trial, Jennifer B. Levin, Farren Briggs, Mahboob Rahman, Kurt Stange, Douglas Einstadter, Celeste Weise, Carla Conroy, Joy Yala, Ethan Radatz, Martha Sajatovic
Faculty Scholarship
Background: Cardiovascular disease in individuals with mental health conditions such as bipolar disorder is highly prevalent and often poorly managed. Individuals with bipolar disorder face significant medication adherence barriers, especially when they are prescribed multiple medications for other health conditions including hypertension. Poor adherence puts them at a disproportionate risk for poor health outcomes. As such, there is a need for effective interventions to improve hypertension medication adherence, particularly in patients that struggle with adherence due to mental health comorbidity. Methods: This 5-year project uses a 2-stage randomized controlled trial design to evaluate a brief, practical adherence intervention delivered via …
Daubert/Kumho Tire And The Legal Malpractice Expert Witness, Warren Trazenfeld, Robert M. Jarvis
Daubert/Kumho Tire And The Legal Malpractice Expert Witness, Warren Trazenfeld, Robert M. Jarvis
Faculty Scholarship
In legal malpractice cases, parties almost always end up using expert witnesses. Whether a particular legal malpractice expert is qualified to testify often is a hotly contested issue. In this Article, the authors provide recommendations for how to qualify a legal malpractice expert and how to challenge a legal malpractice expert’s qualifications.
The “End” Of Neutrality: Tumultuous Times Require A Deeper Value, Carol Pauli
The “End” Of Neutrality: Tumultuous Times Require A Deeper Value, Carol Pauli
Faculty Scholarship
This essay has observed that, when times are tumultuous, third parties who intend to be neutral may need some mooring beyond the norms that are shifting. It argues that neutrality is an unsatisfying value in such times and suggests that neutrals look to the deeper values of their field. It proposes human dignity as a good place to begin, and it invites others to explore whether an initial commitment to the inherent worth of every person would make a helpful difference in practice.
Taking Courthouse Discrimination Seriously: The Role Of Judges As Ethical Leaders, Susan Saab Fortney
Taking Courthouse Discrimination Seriously: The Role Of Judges As Ethical Leaders, Susan Saab Fortney
Faculty Scholarship
Sexual misconduct allegations against Alex Kozinski, a once powerful judge in the U.S. Court of Appeals for the 9th Circuit, spotlighted concerns related to sexual harassment in the judiciary. Following news reports related to the alleged misconduct, Chief Justice John G. Roberts, Jr. charged a working group with examining safeguards to deal with inappropriate conduct in the judicial workplace. Based on recommendations made in the Report of the Federal Judiciary Workplace Conduct Working Group, the Judicial Conference approved a number of reforms and improvements related to workplace conduct in the federal judiciary. The reforms included revising the Code of …
Racial Justice And Peace, Yuvraj Joshi
An Argument Against Unbounded Arrest Power: The Expressive Fourth Amendment And Protesting While Black, Karen Pita Loor
An Argument Against Unbounded Arrest Power: The Expressive Fourth Amendment And Protesting While Black, Karen Pita Loor
Faculty Scholarship
Protesting is supposed to be revered in our democracy, considered “as American as apple pie” in our nation’s mythology. But the actual experiences of the 2020 racial justice protesters showed that this supposed reverence for political dissent and protest is more akin to American folklore than reality on the streets. The images from those streets depicted police officers clad in riot gear and armed with shields, batons, and “less than” lethal weapons aggressively arresting protesters, often en masse. In the first week of the George Floyd protests, police arrested roughly 10,000 people, and approximately 78 percent of those arrests were …
Cop-“Like”: The First Amendment, Criminal Procedure, And The Regulation Of Police Social Media Speech, Jonathan Abel
Cop-“Like”: The First Amendment, Criminal Procedure, And The Regulation Of Police Social Media Speech, Jonathan Abel
Faculty Scholarship
What happens when a law-enforcement officer makes an offensive comment on social media? Increasingly, police departments, prosecutors, courts, and the public have been confronted with the legal and normative questions resulting from officers’ racist, sexist, and violent social media comments. On one side are calls for severe discipline and termination. On the other are demands that officers be permitted to express their views without fear of retaliation. The regulation of police social media speech has been largely conceived of in First Amendment terms. But because an officer’s comments affect her ability to testify, criminal procedure is also employed in regulating …
Langdell And The Foundation Of Classical Contract Law, Daniel P. O'Gorman
Langdell And The Foundation Of Classical Contract Law, Daniel P. O'Gorman
Faculty Scholarship
No abstract provided.
Extrusion: A New Method For Rapid Formulation Of High-Yield, Monodisperse Nanobubbles, Claire Counil, Eric Abenojar, Reshani Perera, Agata A. Exner
Extrusion: A New Method For Rapid Formulation Of High-Yield, Monodisperse Nanobubbles, Claire Counil, Eric Abenojar, Reshani Perera, Agata A. Exner
Faculty Scholarship
Shell-stabilized gas microbubbles (MB) and nanobubbles (NB) are frequently used for biomedical ultrasound imaging and therapeutic applications. While it is widely recognized that monodisperse bubbles can be more effective in these applications, the efficient formulation of uniform bubbles at high concentrations is difficult to achieve. Here, it is demonstrated that a standard mini-extruder setup, commonly used to make vesicles or liposomes, can be used to quickly and efficiently generate monodisperse NBs with high yield. In this highly reproducible technique, the NBs obtained have an average diameter of 0.16 ± 0.05 µm and concentration of 6.2 ± 1.8 × 1010 NBs …
Nondelegation And Originalism, Jack M. Beermann
Nondelegation And Originalism, Jack M. Beermann
Faculty Scholarship
Originalism certainly isn’t what it used to be. From a fringe theory with few adherents it has, in recent decades, become the dominant conservative legal weapon deployed against nearly every liberal legal development since the dawn of the twentieth century, particularly the acceptance of the administrative state and the delegation of rulemaking power to agencies. Professor Kurt Eggert’s recent article adds to the mounting evidence that originalism is not a credible legal theory especially when deployed against Congress’s choices concerning the proper structure of the regulatory state.
Urate-Lowering Therapy For Patients With Gout On Hemodialysis, Reem Alkilany, Douglas Einstadter, Maria Antonelli
Urate-Lowering Therapy For Patients With Gout On Hemodialysis, Reem Alkilany, Douglas Einstadter, Maria Antonelli
Faculty Scholarship
Objective: Gout is the most common form of inflammatory arthritis and is caused by deposition of monosodium urate crystals resulting from a high burden of uric acid (UA). High UA burden also has been associated with increased morbidity and mortality in the general population and progression to chronic kidney disease. In persons with gout and end-stage renal disease (ESRD), prior studies suggest that UA levels decrease after initiation of hemodialysis (HD). We evaluated UA level and the use of urate-lowering therapies (ULTs) in patients with gout and ESRD on HD. Methods: We performed a retrospective review of patients with gout …
The Longitudinal Relationship Between Broken Windows And Sexual Behaviors Among African American Girls In Juvenile Detention: The Moderating Effects Of Sexual Sensation Seeking And Parental Monitoring, Dexter R. Voisin
Faculty Scholarship
Objective: Broken windows theory has been applied in public health to understand how neighborhood disadvantage contributes to health risk and disparities. This longitudinal study examined the relationship between a broken windows index (i.e., a proxy for neighborhood disadvantage) and sexual behaviors and whether sexual sensation-seeking behaviors and parental monitoring moderated that relationship. Method: Participants were 188 African American adolescent girls incarcerated in a short-term detention facility in Atlanta, GA. Participants completed audio computer-assisted self-interviews at baseline, 3, and 6 months; interviews assessed neighborhood disadvantage, sexual risk behaviors, sexual sensation seeking, parental monitoring, and demographics. Results: Longitudinal findings indicate that the …
Atomically Dispersed Janus Nickel Sites On Red Phosphorus For Photocatalytic Overall Water Splitting, Shuai Xu, Clemens Burda
Atomically Dispersed Janus Nickel Sites On Red Phosphorus For Photocatalytic Overall Water Splitting, Shuai Xu, Clemens Burda
Faculty Scholarship
Single-atom nickel catalysts hold great promise for photocatalytic water splitting due to their plentiful active sites and cost-effectiveness. Herein, we adopt a reactive-group guided strategy to prepare atomically dispersed nickel catalysts on red phosphorus. The hydrothermal treatment of red phosphorus leads to the formation of P−H and P−OH groups, which behave as the reactive functionalities to generate the dual structure of single-atom P−Ni and P−O−Ni catalytic sites. The produced single-atom sites provide two different functions: P−Ni for water reduction and P−O−Ni for water oxidation. Benefitting from this specific Janus structure, Ni-red phosphorus shows an elevated hydrogen evolution rate compared to …
Shifting Burdens At The Fringe, Vijay Raghavan
Shifting Burdens At The Fringe, Vijay Raghavan
Faculty Scholarship
No abstract provided.
The Time-Varying Cardiovascular Benefits Of Glucagon-Like Peptide-1 Receptor Agonist Therapy In Patients With Type 2 Diabetes Mellitus: Evidence From Large Multinational Trials, Salil V. Deo, Yakov Elgudin
The Time-Varying Cardiovascular Benefits Of Glucagon-Like Peptide-1 Receptor Agonist Therapy In Patients With Type 2 Diabetes Mellitus: Evidence From Large Multinational Trials, Salil V. Deo, Yakov Elgudin
Faculty Scholarship
Aims: To evaluate the time-varying cardio-protective effect of glucagon-like peptide-1 receptor agonists (GLP-1RAs) using pooled data from eight contemporary cardiovascular outcome trials using the difference in the restricted mean survival time (ΔRMST) as the effect estimate. Material and Methods: Data from eight multinational cardiovascular outcome randomized controlled trials of GLP-1RAs for type 2 diabetes mellitus were pooled. Flexible parametric survival models were fit from published Kaplan-Meier plots. The differences between arms in RMST (ΔRMST) were calculated at 12, 24, 36 and 48 months. ΔRMST values were pooled using an inverse variance-weighted random-effects model; heterogeneity was tested with Cochran's Q statistic. …
Diversity’S Distractions Revisited: The Case Of Latinx In Higher Education, Rachel F. Moran
Diversity’S Distractions Revisited: The Case Of Latinx In Higher Education, Rachel F. Moran
Faculty Scholarship
As the United States Supreme Court considers the future of affirmative action in higher education, this Article reflects on a 2003 essay by Professor Derrick Bell, which provocatively argued that diversity is a distraction from other pressing problems of access to a bachelor’s degree. The Article evaluates his claims with a focus on Latinx students, a rapidly growing segment of the college-going population. Bell believed that diversity is a less compelling justification for the use of race in admissions than corrective justice is. As a result, he predicted persistent litigation over the constitutionality of affirmative action programs. That prediction certainly …
Immigration Detention And Illusory Alternatives To Habeas, Fatma Marouf
Immigration Detention And Illusory Alternatives To Habeas, Fatma Marouf
Faculty Scholarship
The Supreme Court has never directly addressed whether, or under what circumstances, a writ of habeas corpus may be used to challenge the conditions of detention, as opposed to the fact or duration of detention. Consequently, a circuit split exists on habeas jurisdiction over conditions claims. The COVID-19 pandemic brought this issue into the spotlight as detained individuals fearing infection, serious illness, and death requested release through habeas petitions around the country. One of the factors that courts considered in deciding whether to exercise habeas jurisdiction was whether alternative remedies exist, through a civil rights or tort-based action. This Article …
The Truth About Design Patents, Sarah Burstein, Saurabh Vishnubhakat
The Truth About Design Patents, Sarah Burstein, Saurabh Vishnubhakat
Faculty Scholarship
Design patents are hot. Scholars and policymakers are increasingly focusing on this once-niche area of law. However, many of the empirical studies in this area—including old ones that still get cited—were methodologically questionable from the start, have become outdated, or both. In this Article, we make two sets of contributions to this important and underdeveloped literature. First, we review the empirical studies of design patents thus far, including those that pre- and post-date the creation of the U.S. Court of Appeals for the Federal Circuit, and we update the findings of those studies. Second, we consider a set of institutional …
The Public/Private Distinction In Public Health: The Case Of Covid-19, Jason Jackson, Aziza Ahmed
The Public/Private Distinction In Public Health: The Case Of Covid-19, Jason Jackson, Aziza Ahmed
Faculty Scholarship
In this Essay, we argue that the paradigm of the public/private distinction is implicitly operating as a primary frame in the public health response to the pandemic. The public/private distinction is particularly evident in the guidance around masking and other risk-mitigation policies and advice issued by public health agencies. This public health approach reifies the notion of the home as an exceptional private space that exists outside of the possibility of COVID-19 transmission, obscuring the reality of the high risk of transmission in some households. 8 We argue that the manifestation of the public/private distinction in the COVID-19 response is …
Comparing Learning Retention In Medical Students Using Mixed-Reality To Supplement Dissection: A Preliminary Study, Preethy S. Sridharan, Curtis Tatsuoka, Mark A. Griswold, Susanne Wish-Baratz
Comparing Learning Retention In Medical Students Using Mixed-Reality To Supplement Dissection: A Preliminary Study, Preethy S. Sridharan, Curtis Tatsuoka, Mark A. Griswold, Susanne Wish-Baratz
Faculty Scholarship
Objectives: To evaluate student impressions of learning anatomy with mixed-reality and compare long-term information retention of female breast anatomy between students who learned with a mixed-reality supplement and their classmates who dissected cadavers. Methods: In Part 1, 38 first-year medical student volunteers, randomly divided into two groups, completed a mixed-reality module and cadaveric dissection on the female breast in a counterbalanced design. Participants also completed post-quizzes and surveys. Part 2 was a non-randomized controlled trial, 8-months after completing Part 1 and 6-months after a final exam on this content. The performance of twenty-two Part 1 participants and 129 of their …