Digital Commons Network^™

Family History Of Fxtas Is Associated With Age-Related Cognitive-Linguistic Decline Among Mothers With The Fmr1 Premutation, Jessica Klusek, Amanda Fairchild, Carly Moser, Marsha R. Mailick, Angela John Thurman, Leonard Abbeduto

Faculty Publications

BACKGROUND: Women who carry a premutation allele of the FMR1 gene are at increased vulnerability to an array of age-related symptoms and disorders, including age-related decline in select cognitive skills. However, the risk factors for age-related decline are poorly understood, including the potential role of family history and genetic factors. In other forms of pathological aging, early decline in syntactic complexity is observed and predicts the later onset of neurodegenerative disease. To shed light on the earliest signs of degeneration, the present study characterized longitudinal changes in the syntactic complexity of women with the FMR1 premutation across midlife, and associations …

Reef Sediments Can Act As A Stony Coral Tissue Loss Disease Vector, Michael S. Studivan, Ashley M. Rossin, Ewelina Rubin, Nash Soderberg, Daniel M. Holstein, Ian C. Enochs

Faculty Publications

Stony coral tissue loss disease (SCTLD) was first observed in 2014 near Virginia Key in Miami-Dade County, Florida. Field sampling, lab experiments, and modeling approaches have suggested that reef sediments may play a role in SCTLD transmission, though a positive link has not been tested experimentally. We conducted an ex situ transmission assay using a statistically-independent disease apparatus to test whether reef sediments can transmit SCTLD in the absence of direct contact between diseased and healthy coral tissue. We evaluated two methods of sediment inoculation: batch inoculation of sediments collected from southeast Florida using whole colonies of diseased Montastraea cavernosa, …

Long-Term Suppression Of Hardwood Regeneration By Chinese Privet (Ligustrum Sinense), Taylor N. Turner, Thomas J. Dean, Jeff S. Kuehny

Faculty Publications

Native hardwood regeneration in the southeast United States is hindered by repeat disturbance events and the presence of invasive species. Our study aimed to determine the ability of native species in an unmanaged urban forest fragment to persist following high winds from hurricane Gustav in 2008 and subsequent salvage logging. In 2009, researchers estimated the density and composition of the regeneration and overstory trees as well as percent crown cover of invasive Chinese privet. Percent Chinese privet cover was visibly high, leading them to believe it may be inhibiting native hardwood establishment. Ten years later in 2019, we returned to …

Towards A Quantum Notion Of Covariance In Spherically Symmetric Loop Quantum Gravity, Rodolfo Gambini, Javier Olmedo, Jorge Pullin

Faculty Publications

The covariance of loop quantum gravity studies of spherically symmetric space-times has recently been questioned. This is a reasonable worry, given that they are formulated in terms of slicing-dependent variables. We show explicitly that the resulting space-times, obtained from Dirac observables of the quantum theory, are covariant in the usual sense of the way-they preserve the quantum line element-for any gauge that is stationary (in the exterior, if there is a horizon). The construction depends crucially on the details of the Abelianized quantization considered, the satisfaction of the quantum constraints, and the recovery of standard general relativity in the classical …

Towards A Quantum Notion Of Covariance In Spherically Symmetric Loop Quantum Gravity, Rodolfo Gambini, Javier Olmedo, Jorge Pullin

Faculty Publications

The covariance of loop quantum gravity studies of spherically symmetric space-times has recently been questioned. This is a reasonable worry, given that they are formulated in terms of slicing-dependent variables. We show explicitly that the resulting space-times, obtained from Dirac observables of the quantum theory, are covariant in the usual sense of the way-they preserve the quantum line element-for any gauge that is stationary (in the exterior, if there is a horizon). The construction depends crucially on the details of the Abelianized quantization considered, the satisfaction of the quantum constraints, and the recovery of standard general relativity in the classical …

Characterizing Middle School Students' Physical Literacy Development: A Self-Determination Theory-Based Pilot Intervention In Physical Education, Yang Liu, Senlin Chen

Faculty Publications

Purpose: Positive youth development (PYD) can be achieved through effective and purposeful instructions in physical education (PE) and other relevant experiences both in and beyond schools. Students' PYD is associated with their physical literacy (PL) development, which has become a primary emphasis of PE, especially in the United States, in recent years. This study aimed to (a) characterize middle school students' physical literacy (PL) and (b) capture their PL developing trajectories in light of receiving a self-determination theory (SDT)-based pedagogical workshop, with the long-term vision on PYD. Methods: Participants (N = 226) completed the Canadian Assessment of Physical Literacy (CAPL-2) …

Self-Relabeling For Noise-Tolerant Retina Vessel Segmentation Through Label Reliability Estimation, Jiacheng Li, Ruirui Li, Ruize Han, Song Wang

Faculty Publications

Background Retinal vessel segmentation benefits significantly from deep learning. Its performance relies on sufficient training images with accurate ground-truth segmentation, which are usually manually annotated in the form of binary pixel-wise label maps. Manually annotated ground-truth label maps, more or less, contain errors for part of the pixels. Due to the thin structure of retina vessels, such errors are more frequent and serious in manual annotations, which negatively affect deep learning performance.

Methods In this paper, we develop a new method to automatically and iteratively identify and correct such noisy segmentation labels in the process of network training. We consider …

Electromagnetic Multi–Gaussian Speckle, Milo W. Hyde Iv, Olga Korotkova

Faculty Publications

Generalizing our prior work on scalar multi-Gaussian (MG) distributed optical fields, we introduce the two-dimensional instantaneous electric-field vector whose components are jointly MG distributed. We then derive the single-point Stokes parameter probability density functions (PDFs) of MG-distributed light having an arbitrary degree and state of polarization. We show, in particular, that the intensity contrast of such a field can be tuned to values smaller or larger than unity. We validate our analysis by generating an example partially polarized MG field with a specified single-point polarization matrix using two different Monte Carlo simulation methods. We then compute the joint PDFs of …

Improved Chromosome-Level Genome Assembly Of The Glanville Fritillary Butterfly (Melitaea Cinxia) Integrating Pacific Biosciences Long Reads And A High-Density Linkage Map, Olli-Pekka Smolander, Daniel Blande, Virpi Ahola, Pasi Rastas, Jaakko Tanskanen, Juhana Kammonen, Vicencio Oostra, Lorenzo Pellegrini, Suvi Ikonen, Tad Dallas, Michelle F. Dileo, Anne Duplouy, Iihan Cem Duru, Pauliina Halimaa, Aapo Kahilainen, Suyog S. Kuwar, Sirpa O. Kärenlampi, Elvira Lafuente, Shiqi Luo, Jenny Makkonen, Abhilash Nair, Narua De La Paz Celorio-Mancera, Ville Pennanen, Annukka Ruokolainen, Tarja Sundell, Arja I. Tervahauta, Victoria Twort, Erik Van Bergen, Janina Österman-Udd, Lars Paulin, Mikko J. Frilander, Petri Auvinen, Marjo Saastamoinen

Faculty Publications

Background

The Glanville fritillary (Melitaea cinxia) butterfly is a model system for metapopulation dynamics research in fragmented landscapes. Here, we provide a chromosome-level assembly of the butterfly's genome produced from Pacific Biosciences sequencing of a pool of males, combined with a linkage map from population crosses.

Results

The final assembly size of 484 Mb is an increase of 94 Mb on the previously published genome. Estimation of the completeness of the genome with BUSCO indicates that the genome contains 92–94% of the BUSCO genes in complete and single copies. We predicted 14,810 genes using the MAKER pipeline and …

Too Much Is Never Enough: Constructing Electricity Market Demand, Todd S. Aagaard, Andrew N. Kleit

Faculty Publications

Some regions of the United States have created institutions known as capacity markets in an effort to use competitive market forces to ensure adequate electricity supply at lowest cost. But capacity markets are driven more by political and bureaucratic judgments than by competition. The manner in which the capacity market is designed to determine demand exemplifies this observation. As there is no natural demand for capacity, Regional Transmission organizations (RTOs) administratively create demand in capacity markets. RTOs derive capacity demand from three components: the capacity requirement based on forecasted peak demand plus an additional margin, the net cost of new …

Role Of International Research Experiences In The Development Of Women Of Color In Chemistry, R D. Davis, L Winfield, D Spivak, Z S. Wilson-Kennedy, R D. Davis

Faculty Publications

As undergraduate students cultivate their scientific knowledge and abilities, several high-impact educational practices such as undergraduate research and global experiences have proven exponentially beneficial for their development and success. Current literature on underrepresented racial and ethnic minorities has focused primarily on the impact of undergraduate research on this subpopulation. However, fewer studies have explored the impact of global research experiences and women of color in international research experiences. Grounded in the theoretical frameworks of Social Cognitive Career Theory, Intersectionality, and Community Cultural Wealth, this present study explored the impact of international undergraduate research experiences on women of color from groups …

Current Methods And Future Directions In Avian Diet Analysis, Brandon D. Hoenig, Allison M. Snider, Anna M. Forsman, Keith A. Hobson, Steven C. Latta, Eliot T. Miller, Michael J. Polito, Luke L. Powell, Samantha L. Rogers, Thomas W. Sherry, David P.L. Toews, Andreanna J. Welch, Sabrina S. Taylor, Brady A. Porter

Faculty Publications

Identifying the composition of avian diets is a critical step in characterizing the roles of birds within ecosystems. However, because birds are a diverse taxonomic group with equally diverse dietary habits, gaining an accurate and thorough understanding of avian diet can be difficult. In addition to overcoming the inherent difficulties of studying birds, the field is advancing rapidly, and researchers are challenged with a myriad of methods to study avian diet, a task that has only become more difficult with the introduction of laboratory techniques to dietary studies. Because methodology drives inference, it is important that researchers are aware of …

Search For Darkonium In E+ E− Collisions, J. P. Lees, V. Poireau, V. Tisserand, E. Grauges, A. Palano, G. Eigen, D. N. Brown, Yu. G. Kolomensky, M. Fritsch, H. Koch, T. Schroeder, R. Cheaib, C. Hearty, T. S. Mattison, J. A. Mckenna, R. Y. So, V. E. Blinov, A. R. Buzykaev, Milind Purohit, Et. Al.

Faculty Publications

Collider searches for dark sectors, new particles interacting only feebly with ordinary matter, have largely focused on identifying signatures of new mediators, leaving much of dark sector structures unexplored. In particular, the existence of dark matter bound states (darkonia) remains to be investigated. This possibility could arise in a simple model in which a dark photon (A') is light enough to generate an attractive force between dark fermions. We report herein a search for a JPC ¼ 1−− darkonium state, the ϒ_D, produced in the reaction e⁺e⁻ → γϒ_D, ϒ_D → A …

Instructional Design Framework For Construction Materials Training, Hazem Jadallah, Carol J. Friedland, Isabelina Nahmens, Charles Pecquet, Charles Berryman, Yimin Zhu

Faculty Publications

The construction industry is suffering, in part, from a lack of training programs offered to the construction workforce. Unfortunately, most construction training and education research focuses on university student education. Integrating education science theory into construction workforce training has the potential to improve industry training but there is a dearth of studies that present details of this integration process. To address this gap, a training framework was developed to educate material stakeholders on material properties, selection, and installation. This framework is based on andragogical and Universal Design for Learning (UDL) principles. An assessment method evaluates training agendas to improve upon …

Disruptions Of The Human Connectome Associated With Hemispatial Neglect, Sadhvi Saxena, Zafer Keser, Chris Rorden, Leonardo Bonilha, Julius Fridriksson Ph.D., Alexandra Walker, Argye Elizabeth Hillis

Faculty Publications

Background and Objectives

Hemispatial neglect is a heterogeneous and complex disorder that can be classified by frame of reference for “left” vs “right,” including viewer-centered neglect (VCN, affecting the contralesional side of the view), stimulus-centered neglect (SCN, affecting the contralesional side of the stimulus, irrespective of its location with respect to the viewer), or both. We investigated the effect of acute stroke lesions on the connectivity of neural networks that underlie VCN or SCN.

Methods

A total of 174 patients within 48 hours of acute right hemispheric infarct underwent a detailed hemispatial neglect assessment that included oral reading, scene copy, …

Measurements Of The Electron-Helicity Asymmetry In The Quasi-Elastic A ((E) Over Right Arrow, E' O) Process, T. Kolar, S. J. Paul, P. Achenbach, H. Arenhoevel, A. Ashkenazi, J. Beričič, R. Böhm, D. Bosnar, T. Brecelj, E. Cline, E. O. Cohen, M. O. Distler, A. Esser, I. Friščić, R. Gilman, C. Giusti, M. Heilig, M. Hoek, D, Izraeli, Steffen Strauch, Et. Al.

Faculty Publications

We present measurements of the electron helicity asymmetry in quasi-elastic proton knockout from ²H and ¹²C nuclei by polarized electrons. This asymmetry depends on the fifth structure function, is antisymmetric with respect to the scattering plane, and vanishes in the absence of final-state interactions, and thus it provides a sensitive tool for their study. Our kinematics cover the full range in off-coplanarity angle θ_pq, with a polar angle θ_pq coverage up to about 8^◦. The missing energy resolution enabled us to determine the asymmetries for knock-out resulting in different states of the residual …

Refugees From War: Interviews With Elsa And Max Siegmund, Richard Hacken, Marianne Siegmund

Faculty Publications

In 1987, Marianne Siegmund interviewed her parents (Elsa and Max Siegmund) about their lives, which included her own life experiences as well. The family members are of Transylvanian Saxon origins, coming from a minority German-speaking group that has lived in Transylvania (within Hungary and Romania) since the early Middle Ages. This family saga extends in time from World War One through the 1950s and beyond. (The interviews do not necessarily follow chronologically, however.) The family history begins in Székelyudvarhely, a town in Transylvania that has been divided and redivided between Hungary and Romania a number of times. Because of both …

Fine Ash-Bearing Particles As A Major Aerosol Component In Biomass Burning Smoke, Kouji Adachi, Jack E. Dibb, Eric Scheuer, Joseph M. Katich, Joshua P. Schwarz, Anne E. Perring, Braden Mediavilla, Hongyu Guo, Pedro Campuzano-Jost, Jose L. Jimenez, James Crawford, Amber J. Soja, Naga Oshima, Mizuo Kajino, Takeshi Kinase, Lawrence Kleinman, Arthur J. Sedlacek Iii, Robert J. Yokelson, Peter R. Buseck

Faculty Publications

Biomass burning (BB) events are occurring globally with increasing frequency, and their emissions are having more impacts on human health and climate. Large ash particles are recognized as a BB product with major influences on soil and water environments. However, fine-ash particles, which have diameters smaller than several microns and characteristic morphologies and compositions (mainly Ca and Mg carbonates), have not yet been explicitly considered as a major BB aerosol component either in field observations or climate models. This study measured BB aerosol samples using transmission electron microscopy (TEM) and ion chromatography during the Fire Influence on Regional to Global …

Fine Ash-Bearing Particles As A Major Aerosol Component In Biomass Burning Smoke, Kouji Adachi, Jack E. Dibb, Eric Scheuer, Joseph M. Katich, Joshua P. Schwarz, Anne E. Perring, Braden Mediavilla, Hongyu Guo, Pedro Campuzano-Jost, Jose L. Jimenez, James Crawford, Amber J. Soja, Naga Oshima, Mizuo Kajino, Takeshi Kinase, Lawrence Kleinman, Arthur J. Sedlacek Iii, Robert J. Yokelson, Peter R. Buseck

Faculty Publications

Biomass burning (BB) events are occurring globally with increasing frequency, and their emissions are having more impacts on human health and climate. Large ash particles are recognized as a BB product with major influences on soil and water environments. However, fine-ash particles, which have diameters smaller than several microns and characteristic morphologies and compositions (mainly Ca and Mg carbonates), have not yet been explicitly considered as a major BB aerosol component either in field observations or climate models. This study measured BB aerosol samples using transmission electron microscopy (TEM) and ion chromatography during the Fire Influence on Regional to Global …

The Isocaloric Substitution Of Plant-Based And Animal-Based Protein In Relation To Aging-Related Health Outcomes: A Systematic Review, Jiali Zheng, Tianren Zhu, Guanghuan Yang, Longgang Zhao, Fangyu Li, Yong-Moon Park, Fred K. Tabung, Susan E. Steck Phd, Mph, Rd, Xiaoguang Li, Hui Wang

Faculty Publications

Plant-based and animal-based protein intake have differential effects on various aging-related health outcomes, but less is known about the health effect of isocaloric substitution of plant-based and animal-based protein. This systematic review summarized current evidence of the isocaloric substitutional effect of plant-based and animal-based protein on aging-related health outcomes. PubMed and Embase databases were searched for epidemiologic observational studies published in English up to 15 March 2021. Studies that included adults ≥18 years old; use of a nutritional substitution model to define isocaloric substitution of plant protein and animal protein; health outcomes covering mortality, aging-related diseases or indices; and reported …

Evolutionary Analyses Of Visual Opsin Genes In Frogs And Toads: Diversity, Duplication, And Positive Selection, Ryan K. Schott, Leah Perez, Matthew Kwiatkowski, Vance Imhoff, Jennifer M. Gumm

Faculty Publications

Among major vertebrate groups, anurans (frogs and toads) are understudied with regard to their visual systems, and little is known about variation among species that differ in ecology. We sampled North American anurans representing diverse evolutionary and life histories that likely possess visual systems adapted to meet different ecological needs. Using standard molecular techniques, visual opsin genes, which encode the protein component of visual pigments, were obtained from anuran retinas. Additionally, we extracted the visual opsins from publicly available genome and transcriptome assemblies, further increasing the phylogenetic and ecological diversity of our dataset to 33 species in total. We found …

Characterization Of Ti/Sno2 Interface By X-Ray Photoelectron Spectroscopy, Miranda Martinez, Chourasia R. Anil

Faculty Publications

The Ti/SnO2 interface has been investigated in situ via the technique of x-ray photoelectron spectroscopy. Thin films (in the range from 0.3 to 1.1 nm) of titanium were deposited on SnO2 substrates via the e-beam technique. The deposition was carried out at two different substrate temperatures, namely room temperature and 200 C. The photoelectron spectra of tin and titanium in the samples were found to exhibit significant differences upon comparison with the corresponding elemental and the oxide spectra. These changes result from chemical interaction between SnO2 and the titanium overlayer at the interface. The SnO2 was observed to be reduced …

Future Orientation Among Children Affected By Parental Hiv In China: An Exploratory Analysis Of Complex Interactions, Heather L. Mcdaniel, Sayward E. Harrison, Amanda J. Fairchild, Xiaoming Li Ph.D.

Faculty Publications

We utilized an exploratory analytic approach to examine predictors of children's future beliefs, an internal asset associated with resilience among children affected by HIV, with emphasis on complex interactions among multisystem factors. Children (N = 1221) affected by parental HIV in China reported on psychosocial functioning, as well as internal, familial, and community resilience assets. Exploratory data analysis was conducted using a binary segmentation program. Six binary splits on predictors accounted for 22.78% of the variance in future expectation, suggesting interactions between children's perceived control of their future, loneliness, caregiver trust, and social support. Four binary splits accounted for …

Limitations In Representation Of Physical Processes Preven Successful Simulation Of Pm2.5 During Korus-Aq, Katherine R. Travis, James H. Crawford, Gao Chen, Carolyn E. Jordan, Benjamin A. Nault, Hwajin Kim, Jose L. Jimenez, Pedro Campuzano-Jost, Jack E. Dibb, Jung-Hun Woo, Younha Kim, Shixian Zhai, Xuan Wang, Erin E. Mcduffie, Gan Luo, Fangqun Yu, Saewung Kim, Isobel J. Simpson, Donald R. Blake, Limseok Chang, Michelle J. Kim

Faculty Publications

High levels of fine particulate matter (PM2.5) pollution in East Asia often exceed local air quality standards. Observations from the Korea United States-Air Quality (KORUS-AQ) field campaign in May and June 2016 showed that development of extreme pollution (haze) occurred through a combination of long-range transport and favorable meteorological conditions that enhanced local production of PM2.5. Atmospheric models often have difficulty simulating PM2.5 chemical composition during haze, which is of concern for the development of successful control measures. We use observations from KORUS-AQ to examine the ability of the GEOS-Chem chemical transport model to simulate PM2.5 composition throughout the campaign …

Ethnic Differences In Lbms Structure, Lisa M. Johnson

Faculty Publications

This poster reports on structural correlations between low back vowel merger/position and front lax vowel lowering/retraction (Low-Back-Merger Shift or LBMS). Based on analyses of word list recordings from two groups of Utah teens (Pacific Islanders and Euro Americans), I argue that the position of BOT affects the front vowels in the two ethnic groups differently: while the F1 of EA front vowels is inversely correlated with BOT F1, PI front vowels appear to be more sensitive to BOT F2. These results highlight the structural complexity of LBMS and the importance of recruiting ethnically diverse groups of participants for such studies.

Estimation Of The Global Prevalence Of Dementia In 2019 And Forecasted Prevalence In 2050: An Analysis For The Global Burden Of Disease Study 2019, Emma Nichols, Jaimie D. Steinmetz, Stein Emil Vollset, Kai Fukutaki, Julian Chalek, Ismaeel Yunusa Ph. D., Et Al.

Faculty Publications

Background

Methods

Chronic Background Radiation Correlates With Sperm Swimming Endurance In Bank Voles From Chernobyl, Kati Kivisaari, Sara Calhim, Zbyszek Boratyríski, Timothy Mousseau, Anders P. Møller, Tapio Mappes

Faculty Publications

Sperm quantity and quality are key features explaining intra- and interspecific variation in male reproductive success. Spermatogenesis is sensitive to ionizing radiation and laboratory studies investigating acute effects of ionizing radiation have indeed found negative effects of radiation on sperm quantity and quality. In nature, levels of natural background radiation vary dramatically, and chronic effects of low-level background radiation exposure on spermatogenesis are poorly understood. The Chernobyl region offers a unique research opportunity for investigating effects of chronic low-level ionizing radiation on reproductive properties of wild organisms. We captured male bank voles (Myodes glareolus) from 24 locations in the Chernobyl …

Distributed Matrix Tiling Using A Hypergraph Labeling Formulation, Avah Banerjee, Maxwell Reeser, Guoli Ding

Faculty Publications

Partitioning large matrices is an important problem in distributed linear algebra computing, used in ML among others. Briefly, our goal is to perform a sequence of matrix algebra operations in a distributed manner on these large matrices. However, not all partitioning schemes work well with different matrix algebra operations and their implementations (algorithms). This is a type of data tiling problem. In this paper we consider a data tiling problem using hypergraphs. We prove some hardness results and give a theoretical characterization of its complexity on random instances. Additionally we develop a greedy algorithm and experimentally show its efficacy.

Challenges, Inquiry, And Recommendations: Effective Covid-19 Vaccine Management In The Face Of Public Mistrust And Concern, Rosemary M. Caron, M. Girard Dorsey

Faculty Publications

By examining concerns about safety, compliance, and distribution through an interdisciplinary approach of public health and history, we argue that historical and contemporary mistrust of immunizations serves to challenge the successful management of a COVID-19 vaccine program in the U.S. Unique circumstances surrounding the development of a COVID-19 vaccine, including pressure for rapid production, unclear communication from public health officials, and existing resistance to behavioral protective public health policy measures (e.g., mask-wearing) complicate widespread vaccine adoption. Currently, the demand for first and second COVID-19 vaccine doses, as well as the COVID-19 booster, continues to fluctuate in the U.S. population as …

Design, Construction And Operation Of The Protodune-Sp Liquid Argon Tpc, The Dune Collaboration, A. Abed Abud, B. Abi, R. Acciarri, M. A. Acero, M. R. Adames, G. Adamov, D. Adams, M. Adinolfi, A. Aduszkiewicz, J. Aguilar, Z. Ahmad, J. Ahmed, B. Ali-Mohammadzadeh, T. Alion, K. Allison, S. Alonso Monsalve, M. Alrashed, C. Alt, A. Alton, Roberto Petti, Et. Al.

Faculty Publications

The ProtoDUNE-SP detector is a single-phase liquid argon time projection chamber (LArTPC) that was constructed and operated in the CERN North Area at the end of the H4 beamline. This detector is a prototype for the first far detector module of the Deep Underground Neutrino Experiment (DUNE), which will be constructed at the Sandford Underground Research Facility (SURF) in Lead, South Dakota, U.S.A. The ProtoDUNE-SP detector incorporates full-size components as designed for DUNE and has an active volume of 7 × 6 × 7.2 m³. The H4 beam delivers incident particles with well-measured momenta and high-purity particle identification. …