Digital Commons Network^™

Sue First,Negotiate Later, Michael Risch

Faculty Publications

One of the more curious features of patent law is that patents can be challenged by anyone worried about being sued. This challenge right allows potential defendants to file a declaratory relief lawsuit in their local federal district court, seeking a judgment that a patent is invalid or noninfringed. To avoid this home-court advantage, patent owners may file a patent infringement lawsuit first and, by doing so, retain the case in the patent owner’s venue of choice. But there is an unfortunate side effect to such preemptive lawsuits: they escalate the dispute when the parties may want to instead settle …

Photosystem Ii Oxygen-Evolving Complex Photoassembly Displays An Inverse H/D Solvent Isotope Effect Under Chloride-Limiting Conditions, David J. Vinyard, Syed Lal Badshah, M. Rita Riggio, Divya Kaur, Annaliesa R. Fanguy, M. R. Gunner

Faculty Publications

© 2019 National Academy of Sciences. All rights reserved. Photosystem II (PSII) performs the solar-driven oxidation of water used to fuel oxygenic photosynthesis. The active site of water oxidation is the oxygen-evolving complex (OEC), a Mn4CaO5 cluster. PSII requires degradation of key subunits and reassembly of the OEC as frequently as every 20 to 40 min. The metals for the OEC are assembled within the PSII protein environment via a series of binding events and photochemically induced oxidation events, but the full mechanism is unknown. A role of proton release in this mechanism is suggested here by the observation that …

Fisetin, A 3,7,3',4'-Tetrahydroxyflavone Inhibits The Pi3k/Akt/Mtor And Mapk Pathways And Ameliorates Psoriasis Pathology In 2d And 3d Organotypic Human Inflammatory Skin Models, Jean Christopher Chamcheu, Stephane Esnault, Vaqar M. Adhami, Andrea L. Noll, Sergette Banang-Mbeumi, Tithi Roy, Sitanshu S. Singh, Shile Huang, Konstantin G. Kousoulas, Hasan Mukhtar

Faculty Publications

Psoriasis is a chronic immune-mediated skin disease that involves the interaction of immune and skin cells, and is characterized by cytokine-driven epidermal hyperplasia, deviant differentiation, inflammation, and angiogenesis. Because the available treatments for psoriasis have significant limitations, dietary products are potential natural sources of therapeutic molecules, which can repair the molecular defects associated with psoriasis and could possibly be developed for its management. Fisetin (3,7,3',4'-tetrahydroxyflavone), a phytochemical naturally found in pigmented fruits and vegetables, has demonstrated proapoptotic and antioxidant effects in several malignancies. This study utilized biochemical, cellular, pharmacological, and tissue engineering tools to characterize the effects of fisetin on …

On The Humphreys Conjecture On Support Varieties Of Tilting Modules, Pramod N. Achar, William Hardesty, Simon Riche

Faculty Publications

Let G be a simply-connected semisimple algebraic group over an algebraically closed field of characteristic p, assumed to be larger than the Coxeter number. The “support variety” of a G-module M is a certain closed subvariety of the nilpotent cone of G, defined in terms of cohomology for the first Frobenius kernel G . In the 1990s, Humphreys proposed a conjectural description of the support varieties of tilting modules; this conjecture has been proved for G = SL in earlier work of the second author. In this paper, we show that for any G, the support variety of a tilting …

Rapid Microwave-Assisted Biomass Delignification And Lignin Depolymerization In Deep Eutectic Solvents, Pranjali D. Muley, Justin K. Mobley, Xinjie Tong, Brian Novak, Joseph Stevens, Dorel Moldovan, Jian Shi, Dorin Boldor

Faculty Publications

Biomass deconstruction and lignin depolymerization was performed using three different deep eutectic solvents. Various temperature (110°, 130°, and 150 °C) and time (1, 5, 10, 15 min) conditions were tested in a 2450 MHz microwave reactor. Oxalic acid (130 °C, 15 min) and formic acid DES (150 °C, 15 min) gave the highest lignin yield. Microwave heating reduced the processing time significantly. NMR characterization shows that microwave heating promotes selective bond cleavage during lignin depolymerization and has a narrow molecular weight distribution compared to conventional heating techniques. Molecular dynamic simulations showed that certain lignin bonds are stretched under the electric …

Early Negative Affect In Males And Females With Fragile X Syndrome: Implications For Anxiety And Autism, Carla A. Will, Abigail L. Hogan, Elizabeth A. Will, Samuel Mcquillin, Bridgette L. Kelleher, Jane E. Roberts

Faculty Publications

Background Fragile X syndrome (FXS) is a genetic disorder that is highly comorbid with anxiety and autism spectrum disorder (ASD). Elevated negative affect in young children has been associated with increased risk for both anxiety and ASD; however, these relations remain poorly understood in FXS.

Methods The present prospective longitudinal study examined the trajectory of negative affect from infancy through preschool in males and females with FXS and typical development and its relation to anxiety and ASD.

Results Results indicate a complex association reflecting group, developmental, and sex effects. Specifically, the group with FXS displayed a trajectory of increasing negative …

Genericness Of Pre-Inflationary Dynamics And Probability Of The Desired Slow-Roll Inflation In Modified Loop Quantum Cosmologies, Bao Fei Li, Parampreet Singh, Anzhong Wang

Faculty Publications

We study the evolution of a spatially flat Friedmann-Lemaître-Robertson-Walker universe for chaotic and Starobinsky potentials in the framework of modified loop quantum cosmologies. These models result in a nonsingular bounce as in loop quantum cosmology, but with far more complex modified Friedmann dynamics with higher order than quadratic terms in the energy density. For the kinetic-energy-dominated bounce, we obtain analytical solutions using different approximations and compare with numerical evolution for various physical variables. The relative error turns out to be less than 0.3% in the bounce regime for both of the potentials. The generic features of the dynamics - shared …

Nothing But The Best: A Guide To Preaching Powerful Sermons, Rodney A. Palmer

Faculty Publications

"This masterpiece on preaching will prove beneficial to all who desire to improve their preaching prowess. The experienced preacher will be reminded of the best practices of preaching and how to hone their preaching skills. On the other hand, the inexperienced preacher will learn how to avoid the common pitfalls of preaching, and how to prepare and effectively preach biblically sound and practical sermons. Furthermore, Williams’ book is a wonderful resource for present and future female preachers."

Evaluation And Demonstration Of Take Home Laboratory Kit, J. A. Rossiter, S. A. Pope, B. Ll. Jones, John Hedengren

Faculty Publications

This paper discusses some of the reasons for producing take home laboratory kits. This is then supplemented by detailed presentation of three different types of take home kit, alongside the motivations for their design and an evaluation of their efficacy with students.

Perceived Parental Psychological Control Predicts Intraindividual Decrements In Self-Regulation Throughout Adolescence, Laura M. Padilla-Walker, Adam A. Rogers, Madison K. Memmott-Elison

Faculty Publications

The present study examined the intraindividual, longitudinal, cross-lagged associations between adolescents’ perceptions of mothers’ and fathers’ psychologically controlling parenting and their self-regulation from ages 11–17. Using 7 waves of data involving 500 families and their adolescents (Mage 11.29; SD 1.01 at Wave 1), results indicated that adolescent-reported increases in mothers’ and fathers’ psychological control prospectively and uniquely predicted intraindividual decrements in their self- regulation, controlling for prior levels of self-regulation. Sex differences were largely absent except for one, where fathers’ psychological control predicted adolescent females’, but not males’, declines in self-regulation, and where reverse associations manifested. Implications for intervention efforts …

Departmental Leadership: Navigating Productive Tension While In A Paradoxical Role, Rosemary M. Caron

Faculty Publications

The landscape of higher education is dynamic and calls for faculty and academic administrators to not only prepare those entering the workforce with current skills, knowledge, and values but to do so in an environment that is resourceful with the tools, and personnel necessary to educate the citizenry. A critical component in achieving this noble mission is the role of the Department Chair, who spans both the academic and administrative environments. The Department Chair, whether at a public or private institution must serve multiple masters which include, senior academic administrators, departmental faculty, staff, students, parents, alumni, community partners, and donors. …

Patent Litigation: Empirical Analysis, Bernhard Ganglmair, Christian Helmers, Brian Love

Faculty Publications

No abstract provided.

Patent Litigation: Theory, Bernhard Ganglmair, Christian Helmers, Brian Love

Faculty Publications

No abstract provided.

Comeback Measurement Of The Ckm Matrix Element |VCb| From B0 → D*- At Belle, E. Waheed, P. Urquijo, D. Ferlewicz, I. Adachi, K. Adamczyk, H. Aihara, S. Al Said, D.M. Asner, H. Atmacan, T. Aushev, R. Ayad, V. Babu, I. Badhrees, P. Behera, C. Beleño, F. Bernlochner, B. Bhuyan, T. Bilka, J. Biswal, A. Bobrov, Milind Purohit, Et. Al.

Faculty Publications

We present a new measurement of the Cabibbo-Kobayashi-Maskawa matrix element |Vcb| from B⁰ → D^*-ℓ _vℓ decays, reconstructed with the full Belle data set of 711 fb⁻¹ integrated luminosity. Two form factor parametrizations, originally conceived by the Caprini-Lellouch-Neubert (CLN) and the Boyd, Grinstein and Lebed (BGL) groups, are used to extract the product F(1)η_EW||V_cb| and the decay form factors, where F(1) is the normalization factor and η_EW is a small electroweak correction. In the CLN parametrization we find F(1)η_EW||Vcb|=(35.06 ± 0.15 ± 0.56) × 10⁻³, …

Patent Litigation: Institutions, Processes, And Procedures, Bernhard Ganglmair, Christian Helmers, Brian Love

Faculty Publications

No abstract provided.

Patent Litigation: Data Access And Construction, Bernhard Ganglmair, Christian Helmers, Brian Love

Faculty Publications

No abstract provided.

Preparation Of Activated Biochar-Supported Magnetite Composite For Adsorption Of Polychlorinated Phenols From Aqueous Solutions, Byung-Moon Jun, Yejin Kim, Jonghun Han, Yeomin Yoon, Chang Min Park

Faculty Publications

For this study, we applied activated biochar (AB) and its composition with magnetite (AB-Fe₃O₄) as adsorbents for the removal of polychlorophenols in model wastewater. We comprehensively characterized these adsorbents and performed adsorption tests under several experimental parameters. Using FTIR, we confirmed successful synthesis of AB-Fe₃O₄ composite through cetrimonium bromide surfactant. We conducted adsorption tests using AB and AB-Fe₃O₄ to treat model wastewater containing polychlorophenols, such as 2,3,4,6-Tetrachlorophenol (TeCP), 2,4,6-Trichlorophenol (TCP), and 2,4-Dichlorophenol (DCP). Results of the isotherm and the kinetic experiments were well adapted to Freundlich’s isotherm model and the …

Search For Heavy Neutrinos With The T2k Near Detector Nd280, K. Abe, R. Akutsu, A. Ali, C. Andreopoulos, L. Anthony, M. Antonova, S. Aoki, A. Ariga, Y. Ashida, Y. Awataguchi, Y. Azuma, S. Ban, M. Barbi, G. J. Barker, G. Barr, C. Barry, M. Batkiewicz-Kwasniak, F. Bench, V. Berardi, S. Berkman, R. M. Berner, L. Berns, S. Bhadra, S. Bienstock, A. Blondel, S. Bolognesi, B. Bourguille, S. B. Boyd

Faculty Publications

This paper reports on the search for heavy neutrinos with masses in the range 140

Binary Black Hole Population Properties Inferred From The First And Second Observing Runs Of Advanced Ligo And Advanced Virgo, The Ligo Scientific Collaboration, B. P. Abbott, R. Abbott, T. D. Abbott, S. Abraham, F. Acernese, K. Ackley, C. Adams, R. X. Adhikari, V. B. Adya, C. Affeldt, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, L. Aiello, A. Ain, P. Ajith, G. Allen, A. Allocca, M. A. Aloy, P. A. Altin, A. Amato, A. Ananyeva, S. B. Anderson, W. G. Anderson, S. V. Angelova, S. Antier, S. Appert, K. Arai, M. C. Araya, J. S. Areeda, M. Arène

Faculty Publications

We present results on the mass, spin, and redshift distributions with phenomenological population models using the 10 binary black hole (BBH) mergers detected in the first and second observing runs completed by Advanced LIGO and Advanced Virgo. We constrain properties of the BBH mass spectrum using models with a range of parameterizations of the BBH mass and spin distributions. We find that the mass distribution of the more massive BH in such binaries is well approximated by models with no more than 1% of BHs more massive than 45 M and a power-law index of (90% credibility). We also show …

Exploration Of Factors Associated With Perceived Barriers To Cervical Cancer Screening Among Chinese American Women, Wei-Chen Tung, Minggen Lu, Michelle Granner, Jiani Mcdonough, Susan Ervin

Faculty Publications

This study explored factors associated with perceived barriers to Pap smear testing among Chinese American women (CAW). A total of 121 CAW, ages 21–65, living in California and Nevada completed a self-report questionnaire. Data included demographics, prior screening behavior, risk factors, and perceived barriers to screening. Logistic regression models revealed that participants with less education, and who have never been screened were more likely to report (I) worry about getting a Pap smear, (II) expense of a Pap smear, and (III) not knowing where to get a Pap smear. Partner’s resistance to the women’s participation in screening was another barrier …

Quantum Rebound Capacity, Siddhartha Das, Mark M. Wilde

Faculty Publications

Inspired by the power of abstraction in information theory, we consider quantum rebound protocols as a way of providing a unifying perspective to deal with several information-processing tasks related to and extending quantum channel discrimination to the Shannon-theoretic regime. Such protocols, defined in the most general quantum-physical way possible, have been considered in the physical context of the Das-Wilde (DW) model of quantum reading [arXiv:1703.03706]. In [arXiv:1901.05895], it was discussed how such protocols apply in the different physical context of round-trip communication from one party to another and back. The common point for all quantum rebound tasks is that the …

Purpose Trusts As A Planning Tool For The 21st Century, Thomas Simmons, Brad Myers

Faculty Publications

No abstract provided.

Co-Teaching: Collaborative And Caring Teacher Preparation, Colette Rabin

Faculty Publications

This study investigated what happened during the implementation of a co-teaching model for student-teaching from a relational perspective. When analyzed through the theoretical framework of care ethics, teacher-candidates and their mentor-teachers developed caring relationships, acknowledged and negotiated differential power dynamics, and described cultivating a caring climate through dialogue and modeling.

Peptide Nanotube Encapsulated Enzyme Biosensor For Vapor Phase Detection Of Malathion, An Organophosphorus Compound, Christopher W. Edwards, Surachet Duanghathaipornsuk, Mark N. Goltz, Sushil Kanel, Dong-Shik Kim

Faculty Publications

This study explores the use of a butyrylcholinesterase (BChE)-based, reversible reaction biosensor using screen-printed electrodes (SPEs) having a smaller working surface area than the single-use electrodes previously studied. Previous research demonstrated the prospective application of a single-use biosensor fabricated with an acetylcholinesterase (AChE) enzyme encapsulated in peptide nanotubes (PNTs) and enhanced with horseradish peroxidase (HRP) to detect organophosphorus compounds (OPCs) in aqueous and gas phases. In the current study, potential improvements to the biosensor are investigated. BChE-based biosensors were fabricated using PNTs, HRP, and Nafion in combination to increase the reactive surface area, enhance sensitivity, and maintain enzyme stability. Cyclic …

Segmentation Of Severe Occupational Incidents In Agribusiness Industries Using Latent Class Clustering, Fatemeh Davoudi Kakhki, Steven Freeman, Gretchen Mosher

Faculty Publications

One of the principle objectives in occupational safety analysis is to identify the key factors that affect the severity of an incident. To identify risk groups of occupational incidents and the factors associated with them, statistical analysis of workers’ compensation claims data is performed using latent class clustering, for the segmentation of 1031 severe occupational incidents in agribusiness industries in the Midwest region of the United States between 2008–2016. In this study, severe incidents are those with workers’ compensation costs equal to or greater than $100,000 (USD). Based on the latent class clustering results, three risk groups are identified with …

Directional Limits On Persistent Gravitational Waves Using Data From Advanced Ligo's First Two Observing Runs, B. P. Abbott, R. Abbott, T. D. Abbott, S. Abraham, F. Acernese, K. Ackley, C. Adams, R. X. Adhikari, V. B. Adya, C. Affeldt, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, L. Aiello, A. Ain, P. Ajith, G. Allen, A. Allocca, M. A. Aloy, P. A. Altin, A. Amato, A. Ananyeva, S. B. Anderson, W. G. Anderson, S. V. Angelova, S. Antier, S. Appert, K. Arai, M. C. Araya, J. S. Areeda, M. Arène, N. Arnaud

Faculty Publications

We perform an unmodeled search for persistent, directional gravitational wave (GW) sources using data from the first and second observing runs of Advanced LIGO. We do not find evidence for any GW signals. We place limits on the broadband GW flux emitted at 25 Hz from point sources with a power law spectrum at Fα,Θ<(0.05-25)×10-8 erg cm-2 s-1 Hz-1 and the (normalized) energy density spectrum in GWs at 25 Hz from extended sources at ωα(Θ)<(0.19-2.89)×10-8 sr-1 where α is the spectral index of the energy density spectrum. These represent improvements of 2.5-3× over previous limits. We also consider point sources emitting GWs at a single frequency, targeting the directions of Sco X-1, SN 1987A, and the Galactic center. The best upper limits on the strain amplitude of a potential source in these three directions range from h0<(3.6-4.7)×10-25, 1.5× better than previous limits set with the same analysis method. We also report on a marginally significant outlier at 36.06 Hz. This outlier is not consistent with a persistent gravitational-wave source as its significance diminishes when combining all of the available data.

Search For The Isotropic Stochastic Background Using Data From Advanced Ligo's Second Observing Run, B. P. Abbott, R. Abbott, T. D. Abbott, S. Abraham, F. Acernese, K. Ackley, C. Adams, V. B. Adya, C. Affeldt, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, L. Aiello, A. Ain, P. Ajith, G. Allen, A. Allocca, M. A. Aloy, P. A. Altin, A. Amato, A. Ananyeva, S. B. Anderson, W. G. Anderson, S. V. Angelova, S. Antier, S. Appert, K. Arai, M. C. Araya, J. S. Areeda, M. Arène, N. Arnaud, K. G. Arun

Faculty Publications

The stochastic gravitational-wave background is a superposition of sources that are either too weak or too numerous to detect individually. In this study, we present the results from a cross-correlation analysis on data from Advanced LIGO's second observing run (O2), which we combine with the results of the first observing run (O1). We do not find evidence for a stochastic background, so we place upper limits on the normalized energy density in gravitational waves at the 95% credible level of ωGW<6.0×10-8 for a frequency-independent (flat) background and ωGW<4.8×10-8 at 25 Hz for a background of compact binary coalescences. The upper limit improves over the O1 result by a factor of 2.8. Additionally, we place upper limits on the energy density in an isotropic background of scalar- and vector-polarized gravitational waves, and we discuss the implication of these results for models of compact binaries and cosmic string backgrounds. Finally, we present a conservative estimate of the correlated broadband noise due to the magnetic Schumann resonances in O2, based on magnetometer measurements at both the LIGO Hanford and LIGO Livingston observatories. We find that correlated noise is well below the O2 sensitivity.

Gwtc-1: A Gravitational-Wave Transient Catalog Of Compact Binary Mergers Observed By Ligo And Virgo During The First And Second Observing Runs, B. P. Abbott, R. Abbott, T. D. Abbott, S. Abraham, F. Acernese, K. Ackley, C. Adams, R. X. Adhikari, V. B. Adya, C. Affeldt, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, L. Aiello, A. Ain, P. Ajith, G. Allen, A. Allocca, M. A. Aloy, P. A. Altin, A. Amato, A. Ananyeva, S. B. Anderson, W. G. Anderson, S. V. Angelova, S. Antier, S. Appert, K. Arai, M. C. Araya, J. S. Areeda, M. Arène, N. Arnaud

Faculty Publications

We present the results from three gravitational-wave searches for coalescing compact binaries with component masses above 1 Ma™ during the first and second observing runs of the advanced gravitational-wave detector network. During the first observing run (O1), from September 12, 2015 to January 19, 2016, gravitational waves from three binary black hole mergers were detected. The second observing run (O2), which ran from November 30, 2016 to August 25, 2017, saw the first detection of gravitational waves from a binary neutron star inspiral, in addition to the observation of gravitational waves from a total of seven binary black hole mergers, …

Rompi-Cdsa: Ring-Opening Metathesis Polymerization-Induced Crystallization-Driven Self-Assembly Of Metallo-Block Copolymers, Ye Sha, Md Anisur Rahman, Tianyu Zhu, Yujin Cha, C Wayne Mcalister, Chuanbing Tang

Faculty Publications

Polymerization-induced self-assembly (PISA) and crystallization-driven self-assembly (CDSA) are among the most prevailing methods for block copolymer self-assembly. Taking the merits of scalability of PISA and dimension control of CDSA, we report one-pot synchronous PISA and CDSA ring-opening metathesis polymerization (ROMP) to prepare nano-objects based on a crystalline poly(ruthenocene) motif. We denote this self-assembly methodology as ROMPI-CDSA to enable a simple, yet robust approach for the preparation of functional nanomaterials.

Gwtc-1: A Gravitational-Wave Transient Catalog Of Compact Binary Mergers Observed By Ligo And Virgo During The First And Second Observing Runs, Tiffany Summerscales, Ligo Scientific Collaboration And The Virgo Collaboration

Faculty Publications

We present the results from three gravitational-wave searches for coalescing compact binaries with component masses above 1  M_⊙ during the first and second observing runs of the advanced gravitational-wave detector network. During the first observing run (O1), from September 12, 2015 to January 19, 2016, gravitational waves from three binary black hole mergers were detected. The second observing run (O2), which ran from November 30, 2016 to August 25, 2017, saw the first detection of gravitational waves from a binary neutron star inspiral, in addition to the observation of gravitational waves from a total of seven binary black hole …