Digital Commons Network^™

Development Of A Surgical Procedure For Removal Of A Placentome From A Pregnant Ewe During Gestation, Colleen A. Lambo, Ashley K. Edwards, Fuller W. Bazer, Kathrin Dunlap, M. Carey Satterfield

Faculty Publications

Background: In recent decades, there has been a growing interest in the impact of insults during pregnancy on postnatal health and disease. It is known that changes in placental development can impact fetal growth and subsequent susceptibility to adult onset diseases; however, a method to collect sufficient placental tissues for both histological and gene expression analyses during gestation without compromising the pregnancy has not been described. The ewe is an established biomedical model for the study of fetal development. Due to its cotyledonary placental type, the sheep has potential for surgical removal of materno-fetal exchange tissues, i.e., placentomes. A novel …

Multicenter, Observational Cohort Study Evaluating Third-Generation Cephalosporin Therapy For Bloodstream Infections Secondary To Enterobacter, Serratia, And Citrobacter Species, Caroline Derrick, P. Brandon Bookstaver, Zhiqiang K. Lu, Christopher M. Bland, S. Travis King, Kayla R. Stover, Kathey Rumley, Shawn H. Macvane, Jenna Swindler, Scott Kincaid, Trisha Branan, David Cluck, Benjamin Britt, Kelly E. Pillinger, Bruce M. Jones, Virginia Fleming, V. Paul Dimondi, Sandy Estrada, Brad Crane, Brian Odle, Majdi N. Al-Hasan, Julie Ann Justo

Faculty Publications

Objectives: There is debate on whether the use of third-generation cephalosporins (3GC) increases the risk of clinical failure in bloodstream infections (BSIs) caused by chromosomally-mediated AmpC-producing Enterobacterales (CAE). This study evaluates the impact of definitive 3GC therapy versus other antibiotics on clinical outcomes in BSIs due to Enterobacter, Serratia, or Citrobacter species. Methods: This multicenter, retrospective cohort study evaluated adult hospitalized patients with BSIs secondary to Enterobacter, Serratia, or Citrobacter species from 1 January 2006 to 1 September 2014. Definitive 3GC therapy was compared to definitive therapy with other non-3GC antibiotics. Multivariable Cox proportional hazards regression evaluated the impact of …

Do Workplace Characteristics Moderate The Effects Of Attitudes On Father Warmth And Engagement?, Erin Kramer Holmes, Richard J. Petts, Clare R. Thomas, Nathan L. Robbins, Tom Henry

Faculty Publications

Though many fathers want to be warmer, more nurturing, and more actively involved than prior generations (i.e., the new fatherhood ideal), they also embrace a father's traditional role as financial earner. Thus, we hypothesized that fathers' attitudes about their roles would likely interact with workplace characteristics to produce variations in father warmth and engagement. Using a national sample of 1,020 employed U.S. fathers with children ages 2–8 years old, results suggest that adherence to the new fatherhood idea was associated with less father warmth. Also consistent with prior research showing that family friendly work cultures may enable fathers to be …

Uniting And Dividing Influences Of Religion On Parent–Child Relationships In Highly Religious Families, Heather Howell Kelley, Loren D. Marks, David C. Dollahite

Faculty Publications

Religion can have both helpful and harmful influences on relationships. The purpose of this study is to better understand how religion can have both a unifying and a dividing influence on parent–child relationships. Through the use of interviews with 198 highly religious families (N = 476 individuals), we address some of the complexity inherent in religion and examine the influence of three dimensions of religious experience (religious practices, religious beliefs, and religious community). Findings are supported with primary qualitative data. For the highly religious parents and children in this study, 8 times as many unifying accounts of religion than …

Data For Wetlandscapes And Their Changes Around The World, Navid Ghajarnia, Georgia Destouni, Josefin Thorslund, Zahra Kalantari, Imenne Ahlén, Jesús A. Anaya-Acevedo, Juan F. Blanco-Libreros, Sonia Borja, Sergey Chalov, Aleksandra Chalova, Kwok P. Chun, Nicola Clerici, Amanda Desormeaux, Bethany B. Garfield, Pierre Girard, Olga Gorelits, Amy Hansen, Fernando Jaramillo, Jerker Jarsjö, Adnane Labbaci, John Livsey, Giorgos Maneas, Kathryn Mc Curley Pisarello, Sebastián Palomino-Ángel, Jan Pietroń, René M. Price, Victor H. Rivera-Monroy, Jorge Salgado, A. Britta, Samaneh Seifollahi-Aghmiuni, Ylva Sjöberg, Pavel Terskii, Guillaume Vigouroux

Faculty Publications

Geography and associated hydrological, hydroclimate and land-use conditions and their changes determine the states and dynamics of wetlands and their ecosystem services. The influences of these controls are not limited to just the local scale of each individual wetland but extend over larger landscape areas that integrate multiple wetlands and their total hydrological catchment-the wetlandscape. However, the data and knowledge of conditions and changes over entire wetlandscapes are still scarce, limiting the capacity to accurately understand and manage critical wetland ecosystems and their services under global change. We present a new Wetlandscape Change Information Database (WetCID), consisting of geographic, hydrological, …

The Athletic Gut Microbiota, Alex E. Mohr, Ralf Jäger, Katie C. Carpenter, Chad M. Kerksick, Martin Purpura, Jeremy R. Townsend, Nicholas P. West, Katherine Black, Michael Gleeson, David B. Pyne, Shawn D. Wells, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Richard B. Kreider, Bill I. Campbell, Laurent Bannock, Jonathan Scheiman, Craig J. Wissent, Marco Pane, Douglas S. Kalman, Jamie N. Pugh, Carmen P. Ortega-Santos, Jessica A. Ter Haar, Paul J. Arciero, Jose Antonio

Faculty Publications

The microorganisms in the gastrointestinal tract play a significant role in nutrient uptake, vitamin synthesis, energy harvest, inflammatory modulation, and host immune response, collectively contributing to human health. Important factors such as age, birth method, antibiotic use, and diet have been established as formative factors that shape the gut microbiota. Yet, less described is the role that exercise plays, particularly how associated factors and stressors, such as sport/exercise-specific diet, environment, and their interactions, may influence the gut microbiota. In particular, high-level athletes offer remarkable physiology and metabolism (including muscular strength/power, aerobic capacity, energy expenditure, and heat production) compared to sedentary …

Molecular Properties Are A Primary Control On The Microbial Utilization Of Dissolved Organic Matter In The Ocean, Yuan Shen, Ronald Benner

Faculty Publications

The global ocean sequesters a large amount of reduced carbon in dissolved organic molecules that can persist for centuries to millennia. The persistence of dissolved organic carbon (DOC) in the deep ocean has been attributed to inherently refractory molecules and to low concentrations of molecules, but the relative roles of molecular properties and molecular concentrations remain uncertain. We investigate both of these possibilities using bioas-say experiments with unfiltered seawater collected from five depths (50–1500 m) at the Bermuda Atlantic Time-Series Study site. The microbial utilization of compositionally distinct forms of seawater DOC at in situ and elevated concentrations was determined. …

Burnout And Substance Use In Collegiate Athletic Trainers, Leslie W. Oglesby, Andrew R. Gallucci, Christopher J. Wynveen, Kelly R. Ylitalo, Nicholas F. Benson

Faculty Publications

CONTEXT: The Smith Cognitive-Affective Model of Athletic Burnout suggests that athletic trainers (ATs) suffering from burnout may engage in substance use as a coping behavior. Increases in self-reported burnout symptoms are often associated with increases in heavy episodic drinking and tobacco use among various health care providers. However, this relationship has not been examined thoroughly.

OBJECTIVE: To investigate the prevalence of substance use in ATs and identify relationships between symptoms of burnout and substance use among ATs.

DESIGN: Cross-sectional study.

SETTING: Web-based survey.

PATIENTS OR OTHER PARTICIPANTS: A total of 783 certified ATs working full time in the collegiate or …

Kinetic Insights Into The Lignocellulosic Biomass-Based Levulinic Acid Production By A Mechanistic Model, Emília Savioli Lopes, Elmer Ccopa Rivera, Julio César De Jesus Gariboti, Luis Henrique Zimmermann Feistel, João Vitor Dutra, Rubens Maciel Filho, Laura Plazas Tovar

Faculty Publications

© 2020, Springer Nature B.V. Abstract: In this work, a mechanistic model was developed to simulate the kinetics of the production of levulinic acid (LA) from sugarcane bagasse (SCB), rice husk (RH) and soybean straw (SS). The production of LA from those agro-industrial wastes followed the methodology of biorefining in three stages. Experimental data from the third stage (catalytic depolymerization of cellulose) obtained under a wide range of operating conditions were used to estimate the parameters of the model. An optimization procedure based on a genetic algorithm was used to determine the optimal parameter values. The prediction of the concentrations …

Addressing The Social Vulnerability Of Mississippi Gulf Coast Vietnamese Community Through The Development Of Community Health Advisors, Susan Mayfield-Johnson, Danielle Fastring, Daniel Le, Jane Nguyen

Faculty Publications

Background:Resiliency is the ability to prepare for, recover from, and adapt to stressors from adverse events. Social vulnerabilities (limited access to resources, political power, and representation; lack of social capital; aspects of the built environment; health inequities; and being in certain demographic categories) can impact resiliency. The Vietnamese population living along the Mississippi Gulf Coast is a community that has unique social vulnerabilities that impact their ability to be resilient to adverse events. Objectives: The purpose of this project was to address social vulnerability by implementing and evaluating a volunteer Community Health Advisor (CHA) project to enhance community resiliency in …

Disentangling Dust Components In Sn 2010jl: The First 1400 Days, A. M. Bevan, K. Krafton, R. Wesson, J. E. Andrews, E. Montiel, M. Niculescu-Duvaz, M. J. Barlow, I. De Looze, G. C. Clayton

Faculty Publications

The luminous Type IIn SN 2010jl shows strong signs of interaction between the SN ejecta and dense circumstellar material. Dust may be present in the unshocked ejecta; the cool, dense shell (CDS) between the shocks in the interaction region; or in the circumstellar medium (CSM). We present and model new optical and infrared photometry and spectroscopy of SN 2010jl from 82 to 1367 days since explosion. We evaluate the photometric and spectroscopic evolution using the radiative transfer codes mocassin and damocles, respectively. We propose an interaction scenario and investigate the resulting dust formation scenarios and dust masses. We find that …

2020 County Health Rankings Tennessee Data And Updated Substance Abuse 2005-2019, Kelsey L. Grabeel, Jenny Moore

Faculty Publications

No abstract provided.

Volkov-Pankratov States In Topological Superconductors, David J. Alspaugh, Daniel E. Sheehy, Mark O. Goerbig, Pascal Simon

Faculty Publications

We study the in-gap states that appear at the boundaries of both one- A nd two-dimensional topological superconductors. While the massless Majorana quasiparticles are guaranteed to arise by the bulk-edge correspondence we find that they could be accompanied by massive Volkov-Pankratov (VP) states which are present only when the interface is sufficiently smooth. These predictions can be tested in an s-wave superconductor with Rashba spin-orbit coupling placed on top of a magnetic domain wall. We calculate the spin-resolved local density of states of the VP states about the band inversion generated by a magnetic domain wall and find that they …

Disorder By Design: A Data-Driven Approach To Amorphous Semiconductors Without Total-Energy Functionals, Dil K. Limbu, Stephen R. Elliott, Raymond Atta-Fynn, Parthapratim Biswas

Faculty Publications

X-ray diffraction, Amorphous silicon, Multi-objective optimization, Monte Carlo methods. This paper addresses a difficult inverse problem that involves the reconstruction of a three-dimensional model of tetrahedral amorphous semiconductors via inversion of diffraction data. By posing the material-structure determination as a multiobjective optimization program, it has been shown that the problem can be solved accurately using a few structural constraints, but no total-energy functionals/forces, which describe the local chemistry of amorphous networks. The approach yields highly realistic models of amorphous silicon, with no or only a few coordination defects (≤1%), a narrow bond-angle distribution of width 9–11.5°, and an electronic gap …

Synthesis Of Functionalized Tetrahydropyransviacascade Cycloaddition Involving Silyloxyallyl Cation Intermediates, Fatimat O. Badmus, Joshua A. Malone, Frank R. Fronczek, Rendy Kartika

Faculty Publications

© The Royal Society of Chemistry 2020. An expedient synthesis of highly substituted tetrahydrobenzofuranviaan unsymmetrical silyloxyallyl cation is reported. Conveniently generated under catalytic Brønsted acid conditions, nucleophilic capture of this reactive intermediate by silylenolate, followed by Paal-Knorr cascade cyclization in the presence of tosic acid monohydrate effectively constructed the tetrahydrobenzofuran core in a single synthetic step.

Association Of Multisetting Community Programs And Policies With Child Body Mass Index: The Healthy Communities Study, Vicki L. Collie-Akers, Stephen B. Fawcett, Jerry A. Schultz, Kandace K. Fleming, Rebecca E. Swinburne Romine, Lorrene D. Ritchie, Edward A. Frongillo Jr., S Sonia Arteaga

Faculty Publications

INTRODUCTION:

Expert opinion suggests that efforts to address childhood obesity should seek to transform the environments in which children operate. The objective of this study was to describe the extent to which multisetting programs and policies interact with community and child predictors and are associated with child body mass index (BMI) in the 130 US communities participating in the Healthy Communities Study.

METHODS:

For 2 years beginning in fall 2013, we collected data through key informant interviews on community programs and policies related to healthy weight among children that occurred in the 10 years before the interview. We characterized community …

Cardiac Fibrosis And Cardiac Fibroblast Lineage-Tracing: Recent Advances, Xing Fu, Qianglin Liu, Chaoyang Li, Yuxia Li, Leshan Wang

Faculty Publications

© Copyright © 2020 Fu, Liu, Li, Li and Wang. Cardiac fibrosis is a common pathological change associated with cardiac injuries and diseases. Even though the accumulation of collagens and other extracellular matrix (ECM) proteins may have some protective effects in certain situations, prolonged fibrosis usually negatively affects cardiac function and often leads to deleterious consequences. While the development of cardiac fibrosis involves several cell types, the major source of ECM proteins is cardiac fibroblast. The high plasticity of cardiac fibroblasts enables them to quickly change their behaviors in response to injury and transition between several differentiation states. However, the …

Examining Configural, Metric, And Scalar Invariance Of The Pain Catastrophizing Scale In Native American And Non-Hispanic White Adults In The Oklahoma Study Of Native American Pain Risk (Ok-Snap), Jamie L. Rhudy, Randolph D. Arnau, Felicitas A. Huber, Edward W. Lannon, Bethany L. Kuhn, Shreela Palit, Michael F. Payne, Cassandra A. Sturycz, Natalie Hellman, Yvette M. Gureca, Tyler A. Toledo, Joanna O. Shadlow

Faculty Publications

Introduction: Native Americans (NAs) have a higher prevalence of chronic pain than other US racial/ethnic groups, but the mechanisms contributing to this pain disparity are under-researched. Pain catastrophizing is one of the most important psychosocial predictors of negative pain outcomes, and the Pain Catastrophizing Scale (PCS) has been established as a reliable and valid measure of the pain catastrophizing construct. However, before the PCS can be used to study pain risk in NAs, it is prudent to first determine whether the established 3-factor structure of the PCS also holds true for NAs.

Methods: The current study examined the measurement (configural, …

Lignin-Graft-Poly(Lactic- Co-Glycolic) Acid Biopolymers For Polymeric Nanoparticle Synthesis, Carlos E. Astete, Judith U. De Mel, Sudipta Gupta, Ye Rim Noh, Markus Bleuel, Gerald J. Schneider, Cristina M. Sabliov

Faculty Publications

Copyright © 2020 American Chemical Society. A lignin-graft-poly(lactic-co-glycolic) acid (PLGA) biopolymer was synthesized with two types of lignin (LGN), alkaline lignin (ALGN) and sodium lignosulfonate (SLGN), at different (A/S)LGN/PLGA ratios (1:2, 1:4, and 1:6 w/w). 1H NMR and Fourier-transform infrared spectroscopy (FT-IR) confirmed the conjugation of PLGA to LGN. The (A/S)LGN-graft-PLGA biopolymers were used to form nanodelivery systems suitable for entrapment and delivery of drugs for disease treatment. The LGN-graft-PLGA NPs were generally small (100-200 nm), increased in size with the amount of PLGA added, monodisperse, and negatively charged (-48 to -60 mV). Small-angle scattering data showed that particles feature …

Rejuvenation Of Neutrophil Functions In Association With Reduced Diabetes Risk Following Ten Weeks Of Low-Volume High Intensity Interval Walking In Older Adults With Prediabetes – A Pilot Study, David B. Bartlett, Cris A. Slentz, Leslie H. Willis, Andrew Hoselton, Janet L. Huebner, Virginia B. Kraus, Jennifer Moss, Michael J. Muehlbauer, Guillaume Spielmann, Deborah M. Muoio, Timothy R. Koves, Helena Wu, Kim M. Huffman, Janet M. Lord, William E. Kraus

Faculty Publications

Neutrophil dysfunction is a common feature of aging, and is associated with the pathogenesis of many age-related diseases, including type 2 diabetes mellitus (T2DM). Although exercise training improves metabolic health, decreases risk of T2DM, and is associated with improving neutrophil functions, involvement in regular physical activity declines with age. The aim of this study was to determine if neutrophil functions could be improved in association with changes in fitness and metabolic parameters in older adults at risk for T2DM using 10-weeks of low volume high-intensity interval exercise training (HIIT). Ten older (71 ± 5 years) sedentary adults with prediabetes (HbA1c: …

Assessment: Looking For The Stories Behind The Numbers, Ellen Neuhaus

Faculty Publications

No abstract provided.

Assessing Old And New Individual Study Desks, Holt Zaugg, C. Jeffrey Belliston

Faculty Publications

Purpose – This paper examines student perceptions of new individual study desks (ISDs) and how they improved the students’ learning experience.

Design/methodology/approach – The study describes the process for developing new ISDs. When about half of the old ISDs were replaced with new ISDs, two parallel surveys were used to understand why students used the ISDs, what their experiences were and any suggested improvements.

Findings – Results indicate that the new ISDs were used by students for significantly longer periods of time. They enjoyed the ambiance and amenities of the new desks, including a whiteboard used by over 90% of …

Associations Of Mindfulness With Adolescent Outcomes And Sexuality, Chelom E. Leavitt, David B. Allsop, Dean M. Busby, Shayla M. Driggs, Heather M. Johnson, Matthew T. Saxey

Faculty Publications

Introduction: Using an online survey, we evaluated how adolescent trait and state mindfulness was associated with positive adolescent outcomes in non-sexually active and sexually active adolescents. Additionally, we evaluated a newly developed measure, the Sexual Mindfulness Measure (SMM), with adolescents.

Methods: We asked 2000 U.S. adolescents (half boys/girls; 1/3 low, medium, and high incomes) aged 13–18 (one group 13–15, another 16–18) about trait mindfulness, sexual state mindfulness, and adolescent outcomes. Using Confirmatory Factor Analysis and structured equation modeling, we evaluated the reliability and validity of the SMM and its associations with adolescent outcomes.

Results: Using a trait mindfulness measure, we …

Life History Divergence In Livebearing Fishes In Response To Predation: Is There A Microevolution To Macroevolution Barrier?, Mark C. Belk, Spencer J. Ingley, Jerald B. Johnson

Faculty Publications

A central problem in evolutionary biology is to determine whether adaptive phenotypic variation within species (microevolution) ultimately gives rise to new species (macroevolution). Predation environment can select for trait divergence among populations within species. The implied hypothesis is that the selection resulting from predation environment that creates population divergence within species would continue across the speciation boundary such that patterns of divergence after speciation would be a magnified accumulation of the trait variation observed before speciation. In this paper, we test for congruence in the mechanisms of microevolution and macroevolution by comparing the patterns of life history divergence among three …

Legendrian Dga Representations And The Colored Kauffman Polynomial, Justin Murray, Dan Rutherford

Faculty Publications

For any Legendrian knot K in standard contact R-3 we relate counts of ungraded (1-graded) representations of the Legendrian contact homology DG-algebra (A(K), partial derivative) with the n-colored Kauffman polynomial. To do this, we introduce an ungraded n-colored ru-ling polynomial, R-n,K(1)(q), as a linear combination of reduced ruling polynomials of positive permutation braids and show that (i) R-n,K(1)(q) arises as a specialization F-n,F-K(a, q)vertical bar(a-1) = 0 of the n-colored Kauffman polynomial and (ii) when q is a power of two R-n,K(1)(q) agrees with the total ungraded representation number, Rep(1) (K, F-q(n)), which is a normalized count of n-dimensional representations …

Chemical And Thermal Sintering Of Supported Metals With Emphasis On Cobalt Catalysts During Fischer−Tropsch Synthesis, Mahmood Rahmati, Mohammad-Saeed Safdari, Thomas H. Fletcher, Morris D. Argyle, Calvin H. Bartholomew

Faculty Publications

This comprehensive critical review combines, for the first time, recent advances in nanoscale surface chemistry, surface science, DFT, adsorption calorimetry, and in situ XRD and TEM to provide new insights into catalyst sintering. This work provides qualitative and quantitative estimates of the extent and rate of sintering as functions of nanocrystal (NC) size, temperature, and atmosphere. This review is unique in that besides summarizing important, useful data from previous studies, it also advances the field through addition of (i) improved or new models, (ii) new data summarized in original tables and figures, and (iii) new fundamental perspectives into sintering of …

Hereditary Cancer Syndrome Recognition And Testing: Beyond Brca, Deborah O. Himes, Hanford B. Shuman

Faculty Publications

Hereditary cancer syndromes, resulting from mutations of tumor suppressor genes, can significantly increase the risk for breast cancer. Although hereditary breast and ovarian cancer syndrome caused by BRCA1/2mutations is well-known, less well-known hereditary cancer syndromes also exist. This article focuses on 3 other syndromes, including Li-Fraumeni, Cowden, and Peutz-Jeghers. This article will help prepare nurse practitioners to recognize key clinical features of these syndromes and understand testing criteria. Additionally, this article discusses barriers to diagnosing hereditary cancer syndromes and the role of primary care nurse practitioners in ordering genetic tests and making genetic referrals for optimal patient care.

A Qualitative Investigation Of Middle School Students' Perceptions Of Appropriate Instructional Practices In Physical Education, David C. Barney

Faculty Publications

For many middle school (MS) students they have been exposed to many inappropriate instructional practices in physical education (PE). This involvement and exposure to these inappropriate instructional practices become common occurrences, thus in their mind this is what is supposed to happen in their PE class. The purpose of this study was to better understand MS student’s perceptions and attitudes to appropriate instructional practices (AIP) in their PE classes. It was generally found from student interviews that dodge ball is appropriate to play in PE class, wearing prescribed clothing (school shirt) will earn and easy ‘A’ in PE class, and …

A Physics-Based Machine Learning Study Of The Behavior Of Interstitial Helium In Single Crystal W–Mo Binary Alloys, Adib J. Samin

Faculty Publications

In this work, the behavior of dilute interstitial helium in W–Mo binary alloys was explored through the application of a first principles-informed neural network (NN) in order to study the early stages of helium-induced damage and inform the design of next generation materials for fusion reactors. The neural network (NN) was trained using a database of 120 density functional theory (DFT) calculations on the alloy. The DFT database of computed solution energies showed a linear dependence on the composition of the first nearest neighbor metallic shell. This NN was then employed in a kinetic Monte Carlo simulation, which took into …

Innovation In Sport For Development And Peace, Per G. Svensson, Adam Cohen

Faculty Publications

No abstract provided.