Digital Commons Network^™

Remote Language Assessment In School-Age Children With Phelan–Mcdermid Syndrome And Genotype–Phenotype Correlation, Sarah Quadri-Valverde, Jessica Klusek Ph.D., Ccc-Slp, Linda D. Ward, Diana Ivankovic, Nancy Powers, Vijay Shankar, Rachel A. Lyman, Trudy F.C. Mackay, William Bridges, Katy Phelan, Chris Rogers, Luigi Boccuto, Sara M. Sarasua

Faculty Publications

People with Phelan–McDermid syndrome (PMS) have reduced speech and language abilities, yet little research has profiled the communication abilities in this population. The purpose of this study was threefold: identifying the language and communication profiles of school-aged children with PMS, identifying genetic contributions to language and communication abilities, and determining the feasibility of remote data collection for research purposes. A speech language pathologist used standardized assessments and direct evaluations by video conferencing to evaluate language and communication abilities. Sixteen children and adolescents were evaluated: 5 with SHANK3 pathogenic variants, 9 with 22q13 deletions including SHANK3 (PMS-SHANK3 related), and 2 …

Using Mobile Devices To Support Outdoor Stem Learning In Rural Contexts: An Embedded Mixed-Methods Study, Jayson Seaman, Amanda Bastoni, Andrew D. Coppens, Cindy L. Hartman, Courtney Lachaine, Katelyn Moscouver, Janet Gronneberg

Faculty Publications

Background: Rural youth face barriers to involvement in effective Science, Technology, Engineering, and Math (STEM) learning experiences, leading to persistent underrepresentation in STEM fields. Purpose: This study examined the feasibility of using mobile devices to engage rural youth in informal STEM learning (ISL) during free-choice, outdoor recreational activities. We assessed outcomes of a 10-month intervention related to STEM interest, identity, and future planning. Method: Fifty-four youth ages 12 to 17 completed monthly STEM challenges delivered via a mobile platform, aligned with connected learning and free-choice learning principles. Surveys measured pre/post changes in STEM supports, STEM confidence, and …

Primary School Physical Activity Culture In The Uk: Findings From A Four-Month Rapid Ethnography In Three Schools, Robert Walker, Lydia Emm-Collison, Danielle House, Simoona Kent-Saisch, Ruth Salway, Alice Porter, Abi Howard, Tom Reid, Michael Beets Med, Mph, Phd, Frank De Vocht, Russell Jago

Faculty Publications

Introduction: Physical activity is fundamental for children’s health and well-being, yet most children are not active enough. School-based interventions aiming to increase children’s physical activity have largely been ineffective, perhaps due to a lack of consideration of the unique culture within each school. The aim of this paper is to understand the key aspects of physical activity culture in English primary schools using the organizational culture framework.

Methods: A four-month rapid ethnography study was conducted within three primary schools in Bristol, UK, between March and July 2024. The findings draw on observations, interviews, documentary data, photo elicitation, informal conversations and …

Learning From The Storm: The Impact Of Hurricane Experience On Future Disaster Preparedness, Eren Bilen, Tamara Sheldon, Crystal Zhan

Faculty Publications

Hurricanes and tropical cyclones have become more severe over the past 40 years and are expected to intensify in the future due to climate change. In this paper, we seek to understand how natural disaster experiences shape precautionary economic behaviors in response to future risks. We combine daily, household-level consumer goods purchase data from 2008-2018 with hurricane hit and warning data and use propensity score trimming to obtain a sample of households with a similar probability of receiving a hurricane warning to mitigate the problem of endogenous residential sorting. Using a triple difference-in-differences model, we find that past hurricane experience …

Learning From The Storm: The Impact Of Hurricane Experience On Future Disaster Preparedness, Eren Bilen, Tamara Sheldon, Yi Crystal Zhan

Faculty Publications

Hurricanes and tropical cyclones have become more severe over the past 40 years and are expected to intensify in the future due to climate change. In this paper, we seek to understand how natural disaster experiences shape precautionary economic behaviors in response to future risks. We combine daily, household-level consumer goods purchase data from 2008-2018 with hurricane hit and warning data and use propensity score trimming to obtain a sample of households with a similar probability of receiving a hurricane warning to mitigate the problem of endogenous residential sorting. Using a triple difference-in-differences model, we find that past hurricane experience …

Examining The Relationships Between Students’ Achievement Goals And Their Academic Achievement In An Oer-Based Course: A Person-Centered Approach, Hengtao Tang Ph.D., Yan Yang, Yu Bao

Faculty Publications

Open Educational Resources (OER) have emerged as a cost-effective alternative to traditional commercial textbooks in higher education, towards the goal of alleviating college students’ financial burden of educational expenses. However, mixed findings about the influences of the integration of OER on student learning are present. To address the gap, this study investigated whether student motivation in OER served as a latent factor that impacts their academic achievement in online asynchronous courses offered in public universities. Particularly, this study (N = 247) implemented an advanced person-centered approach—stepwise latent class analysis—to profile student achievement goals in an OER-based course and examined their …

Ephemerality As Stigma In Algorithmic Contexts: Moderation And User-Driven Deletion Of Nonsuicidal Self-Injury Content On Tiktok, Valerie Vera Lookingbill, Ehsan Mohammadi Ph.D.

Faculty Publications

Social media increasingly serves as important spaces for mental health information seeking and peer support, especially for individuals facing barriers to traditional care. Although nonsuicidal self-injury is frequently discussed on social media, there is limited understanding of the factors that influence the visibility of this discourse. We analyzed 973 videos related to nonsuicidal self-injury on TikTok to examine the prevalence and characteristics of posts that become unavailable (i.e., ephemeral) over time, whether due to user deletion or platform removal. Videos that used addiction-related language, included trigger warnings, or depicted scars were significantly associated with ephemerality. These findings highlight how anticipated …

The Sortee Guidelines For Data And Code Quality Control In Ecology And Evolutionary Biology, Joel L. Pick, Bethany J. Allen, Benedicte Bachelot, Kevin R. Bairos-Novak, Jack A. Brand, Barbara Class, Tad Dallas, Pietro B. D'Amelio, Erola Fenollosa, Esteban Fernández-Juricic, Dylan G. Gomes, Matthew J. Grainger, Thomas Guillemaud, John Christian, Ruby Krasnow, Malgorzata Lagisz, Sebastian Lequime, Daniel S. Maynard, Shinichi Nakagawa, Rose E. O'Dea, Et. Al.

Faculty Publications

Open data and code are crucial to increasing transparency and reproducibility, and in building trust in scientific research. However, despite an increasing number of journals in ecology and evolutionary biology mandating for data and code to be archived alongside published articles, the amount and quality of archived data and code, and subsequent reproducibility of results, has remained worryingly low. As a result, a handful of journals have recruited dedicated data editors, whose role is to help authors increase the overall quality of archived data and code. There is, however, a general lack of consensus around what a data editor should …

Social Network Determinants Of Cigarette Forgoing And Quit-Related Conversations In A 15-Day Ecological Momentary Assessment Study In Mexico And The Us, Lizeth Cruz-Jiménez, Kevin A. Carson, Jim Thrasher Ph.D., Ma, Ms, Katia Gallegos-Carrillo, Dèsirée Vidaña-Pérez, Diego F. Leal

Faculty Publications

Introduction

Methods

New Avenues For |Δb=2| Processes Beyond Neutron-Antineutron Oscillations, Arnau Basi Beneito, Svjetlana Fajfer, Alexey A. Petrov

Faculty Publications

We explore baryon-number-violating (|∆B| = 2) processes beyond the well-known neutron-antineutron (n-n̄) oscillations, focusing on the Λ-Λ̄ system. The presence of a strange quark in the Λ baryon introduces a new set of six-quark operators roughly of the form (uds)², which are different from the (udd)² operators responsible for n-n̄ oscillations. Using the Standard Model Effective Field Theory (SMEFT), we classify all dimension-9 operators that cause |∆B| = 2  transitions and study their UV completions mediated by exotic scalar fields with trilinear interactions. We demonstrate that …

Roadmap: Integrating Artificial Intelligence In Structural Health Monitoring Systems, Simon Laflamme, Erik Blasch, Flippo Ubertini, Zheng Liu, John Wertz, Christine Knott, Matthew Cherry, Eric Lindgren, Fu-Kuo Chang, Amrita Kumar, Jack Poole, Keith Worden, Austin Downey, Jie Wei, Patrick F. Musgrave, Adrian S. Wong, Guiseppe Quaranta, Marco Martino Rosso, Giuseppe Carlo Marano, Yu Chen, Et. Al.

Faculty Publications

Advances in computing and machine learning (ML) methods have led to a rapid rise in artificial intelligence (AI) research and applications in many fields. AI research benefitted from advances in computation hardware, collection and distribution of large data sets, and proliferation of software techniques. AI techniques include ML for provable results, deep learning for data exploration, reinforcement learning for control, and active learning for adaptive systems. Likewise, AI algorithms can handle large amounts of data, construct unknown representations, and provide a direct link between data and classification for decision making. These unmatched capabilities have been seen as a path to …

Rewriting The Rules: Game-Based Learning For Affective And Cognitive Student Engagement In An Undergraduate History Course, Rachel Hoke, James Risk

Faculty Publications

Constructivist psychology has long demonstrated the potential for play to offer various benefits to learning. This study introduced active game-based learning experiences, in the form of role-playing games, into an undergraduate history course that also included passive lecture and discussion elements. Mixed methods student feedback surveys were used to examine the impacts of game-based learning on students’ affective and cognitive engagement in the course and offer a comparison between the lecture and game-based learning experiences. Qualitative data were analyzed through the paradigm of Mohsen, Abdollahi, and Omar’s (2019, 518-520) framework for educational value, including affective evaluation, conceptual understanding, skill development, …

Efficient Energy-Stable Discontinuous Galerkin Schemefor The Non-Isothermal Cahn–Hilliard–Navier–Stokestwo-Phase Fluid Flow System, Guang-An Zou, Meiting Wang, Kejia Pan, Yin Yang, Xiaofeng Yang

Faculty Publications

In this article, we propose a novel numerical framework for the non-isothermal Cahn–Hilliard–Navier–Stokes two-phase flow system, which couples the incompressible Navier–Stokes equations, the Cahn–Hilliard phase-field equation, and the heat transport equation to capture temperature-dependent two-phase flow dynamics. The pro-posed scheme achieves three major advances: (i) unconditional energy stability through a combined scalar auxiliary variable (SAV) and zero-energy-contribution (ZEC) approach, (ii) linearity and full decoupling of all variables while using a second-order temporal discretization, and (iii) efficient implementation via discontinuous Galerkin (DG) spa-tial discretization together with a second-order projection method for the Navier–Stokes equations. We rigorously prove the unconditional energy stability …

Ulk4 And Cdkn2a Polymorphisms Influence The Risk Of Developing Monoclonal Gammopathy Of Undetermined Significance, José Manuuel Sánchez-Maldonado, Angelica Macauda, Antonio José Cabrera-Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany Van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz-Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero-Fernández, Elena Cabezudo, Fernando Reyes-Zurita, Alyssa I. Clay-Gilmour, Et. Al.

Faculty Publications

Monoclonal gammopathy of undetermined significance (MGUS) is a necessary precursor condition to multiple myeloma (MM). Given the role of autophagy in modulating MM risk, we investigated whether genetic variation in autophagy-related genes influences susceptibility to MGUS. We analyzed the association of 34,042 common autophagy-related single nucleotide polymorphisms (SNPs) with MGUS across six independent cohorts, five from Europe and one from North America, comprising 2317 MGUS cases and 282,358 controls. We also assessed their impact on immune parameters, including absolute counts of 91 blood-derived immune cell subsets and 103 circulating immunological proteins. Meta-analysis revealed a genome-wide significant association between the ULK4 …

Moderate-Temperature Hydrothermal Treatment Removes Detectable Dna And Antibiotic Resistance Genes From Municipal Sludge While Preserving Resource Value, R Sean Norman M.Sc., Ph.D., Mirza Isanovic, Gabrielle Kartzmark, Nicole Berge

Faculty Publications

Wastewater treatment plants (WWTPs) are key reservoirs of antibiotic resistance genes (ARGs), with municipal sludge containing high bacterial densities and diverse ARGs that may spread through land application. Hydrothermal treatment (HT) is a process that inactivates pathogens and stabilizes biomass, but its performance at moderate temperatures is less understood. We evaluated HT (100°C–250°C; 2–24 h) for degrading bacterial DNA and ARGs in dewatered municipal sludge. DNA was quantified by fluorometry, bacterial presence confirmed by 16S rRNA gene PCR, and ARGs profiled by qPCR targeting 84 clinically and environmentally relevant genes. HT up to 250°C produced modest carbon densification, high solids …

Moderate-Temperature Hydrothermal Treatment Removes Detectable Dna And Antibiotic Resistance Genes From Municipal Sludge While Preserving Resource Value, R. Sean Norman, Mirza Isanovic, Gabrielle Kartzmark, Nicole Berge

Faculty Publications

Wastewater treatment plants (WWTPs) are key reservoirs of antibiotic resistance genes (ARGs), with municipal sludge containing high bacterial densities and diverse ARGs that may spread through land application. Hydrothermal treatment (HT) is a process that inactivates pathogens and stabilizes biomass, but its performance at moderate temperatures is less understood. We evaluated HT (100°C–250°C; 2–24 h) for degrading bacterial DNA and ARGs in dewatered municipal sludge. DNA was quantified by fluorometry, bacterial presence confirmed by 16S rRNA gene PCR, and ARGs profiled by qPCR targeting 84 clinically and environmentally relevant genes. HT up to 250°C produced modest carbon densification, high solids …

Rural–Urban Differences In Cognitive Outcomes Among Older Adults: The Roles Of Falls And Depressive Symptoms, Ayse Malatyali, Tom Cidav, Lisa A.K. Wiese, Jian Zou, Monique J. Brown Ph.D., Mph, Junfeng Ma, Breno S. Diniz, Ladda Thiamwong

Faculty Publications

Background: Older adults with Alzheimer’s Disease and Related Dementias (ADRD) experience a higher risk of falls. However, research lacks evidence on the effect of fall exposure on cognitive impairment and dementia. We investigated the association of falls and depressive symptoms with cognitive impairment and dementia in a nationally representative sample. Methods: We analyzed data from 6221 participants (age ≥ 65) in the Health and Retirement Study (HRS) from the 2018–2020 waves, using Multinomial logistic regression models. Measures included the HRS health status questionnaire, HRS cognition scale, and the Center for Epidemiological Studies Depression scale. Results: Prevalence of fall exposure across …

Rural–Urban Differences In Cognitive Outcomes Among Older Adults: The Roles Of Falls And Depressive Symptoms, Ayse Malatyali, Tom Cidav, Lisa A.K. Wiese, Jian Zou, Monique J. Brown Ph.D., Mph, Junfeng Ma, Breno S. Diniz, Ladda Thiamwong

Faculty Publications

Background: Older adults with Alzheimer’s Disease and Related Dementias (ADRD) experience a higher risk of falls. However, research lacks evidence on the effect of fall exposure on cognitive impairment and dementia. We investigated the association of falls and depressive symptoms with cognitive impairment and dementia in a nationally representative sample. Methods: We analyzed data from 6221 participants (age ≥ 65) in the Health and Retirement Study (HRS) from the 2018–2020 waves, using Multinomial logistic regression models. Measures included the HRS health status questionnaire, HRS cognition scale, and the Center for Epidemiological Studies Depression scale. Results: Prevalence of fall exposure across …

Main-Chain Ion-Pair Polybenzimidazole Membranes Enabling Reduced-Temperature Ht-Pemfc Operation (Down To 120°C), Huina Lin, Brian C. Benicewicz

Faculty Publications

Proton exchange membrane (PEM) fuel cells are promising for clean and efficient energy conversion across diverse applications. High-temperature PEM fuel cells (HT-PEMFCs) using phosphoric acid (PA)-doped polybenzimidazole (PBI) can operate up to 200°C, but at lower temperatures, water-induced PA loss often leads to performance degradation and reduced durability. In this work, we present a new class of main-chain ion-pair PBI membranes by integrating the imidazolium-biphosphate ion-pair units directly into the PBI backbone. This design results in membranes with high acid content, stronger acid-polymer interactions and stabilized acid retention. In single-cell tests, the Im⁺-PBI15-3 wt.% exhibits peak power densities …

Beyond Catalysts And Membranes: Using Cell Assembly And Operating Strategies To Significantly Improve The Performance Of Aem Electrolyzers, Mahmoud Amirsalehi, Venkata Sai Sriram Mosali, Mohammed Al-Murisi, Shaghayegh Bashiri, Hari Gopi, Pongsarun Satjaritanun, Benjamin Britton, Karen Swider-Lyons, Mustain E. William

Faculty Publications

Green hydrogen, produced through water electrolysis, is a key enabler of a low-carbon energy future, and anion exchange membrane electrolyzers (AEMELs) have emerged as a promising technology due to their potential for ultra-low-cost operation. However, achieving low cell voltage at high current densities and maintaining long-term durability remain key AEMEL challenges. To address these issues, most research efforts to date have focused on developing advanced catalysts and membranes. In contrast, the influence of non-material factors, such as cell assembly parameters and operating conditions, remains underexplored, even though they can significantly impact performance. This study investigates how such variables affect AEMEL …

More Rights, More Danger For Police: An Experimental Look At How Messaging Shapes Public Views About Constitutional Carry, Hunter M. Boehme, Paige Vaughn

Faculty Publications

Constitutional carry (CC) laws, now enacted in 29 states, allow individuals to carry firearms openly without permits, yet little is known about public perceptions of these laws. This study employs a pre-registered survey experimental design to investigate whether varying support for CC laws by police leaders and politicians influences attitudes toward the laws and their perceived consequences. One-third of respondents supported CC laws, with most disagreeing that they will make communities safer. The majority of the sample felt these laws would increase personal liberty but also felt these laws would increase police danger. Oppositional messaging increased agreement that the laws …

Cognitive And Emotional Conflict Control Among Children Affected By Parental Hiv/Aids In China, Huihui Wang, Juan Liu, Danfeng Wen, Wan Zhao, Xiaoming Li Ph.D., Junfeng Zhao

Faculty Publications

Background: Children affected by parental HIV/AIDS constitute a particularly vulnerable population, often facing heightened risks in psychosocial adaptation due to family disruption, social stigma, and resource deprivation. However, the characteristics of their executive functions, particularly the core component of conflict monitoring, remain unclear.

Methods: The present study compared the performance of children affected by parental HIV/AIDS (n=32) to a control group (n=32) on a cognitive conflict and emotional conflict face-word Stroop task.

Results: The results of the cognitive Stroop task demonstrated that both groups showed better performance in congruent stimuli compared to incongruent stimuli (86.20% vs.67.30%; 568.43ms vs.586.04ms). In the …

Impediments To Transforming The Healthcare Delivery System: Shifting The Paradigm From Provider Centric To Patient Centric, Elizabeth A. Regan, Manasa Devi Chinta

Faculty Publications

Introduction: 

Stated aims for digital healthcare transformation frequently cite goals for better coordinated patient-centric systems. However, despite advances in medical science, digital technologies, health policies, and billions of dollars invested over the past 25 years, most healthcare providers are far from fully realizing the demonstrated benefits of today's digital technologies for improving patient care. Sharing information across healthcare systems remains challenging. Problems with fragmentation, quality, inequities, and rising costs of care delivery persist. A recent study of 1,026 U.S. hospital systems found that only 15.8 percent achieved a digital maturity level needed to provide digitally enabled healthcare services to better …

Korean Words In The Oed: Race, Gender, And The Modern English Speaker, Elaine W. Chun

Faculty Publications

This article examines representations of the Modern English Speaker of Korean (MESK) in the Oxford English Dictionary (OED), as lexicographers listened to and documented the language of this figure over the past century. I show that, until the early twenty-first century, the most salient type of MESK was the Koreanist, a white, masculine expert on and translator of Korean, the language of a racial other. By contrast, more recent Korean entries, influenced by the global spread of hallyu, have invoked the Korea Fan, a figure that potentially unsettles longstanding ideologies of language, race, and gender. I …

A Review Of Interaction Between Sleep Apnea And Apoe E4 On The Risk Of Dementia, Xiuhua Ding, Carol Watwood, Amit Patel, Krupa Hegde, Brooke Mahanna, Lindsey Escudero, Jean Neils-Strunjas Ph.D, Ccc-Slp

Faculty Publications

Dementia has a significant impact on individuals, families, communities, and the economy. Alzheimer’s disease (AD) accounts for 60–80% of dementia cases. The APOE e4 allele is well known as the primary genetic risk factor for AD and dementia. Studies have also shown that sleep apnea increases the risk of dementia. Some research further suggests a possible interaction between sleep apnea and the APOE in dementia development; however, this relationship remains unclear. The purpose of this study is to synthesize evidence from the existing literature and report findings on the relationship between APOE, sleep apnea, and dementia. A systematic search of …

Influence Of Pulse Width On Energy Deposition And Temperature In Nanosecond-Pulsed Discharges, Christopher B. Reuter, Joshua B. Sinrud, Tanvir I. Farouk, Nicholas S. Dewey, Dmitri Kaganovich

Faculty Publications

Nanosecond-pulsed discharges are a promising method to enhance combustion but can generate significant levels of electromagnetic interference (EMI). Modifying the discharge pulse width is an unexplored option to reduce EMI, but few studies have examined how changing the pulse width affects discharge parameters such as energy and temperature. This study addresses this issue by systematically investigating how the pulse width affects the energy per pulse, breakdown time, rotational temperature, and vibrational temperature in air across different frequencies, flow velocities, and gap distances in a plasma-assisted flow tube. It is observed that the pulse width has a substantial impact on the …

Handling Item-Level Missing Data In Linear Regression: A Tutorial, Guyin Zhang, Lihan Chen, Dexin Shen

Faculty Publications

With advances in methodology and statistical software, modern methods for handling missing data have become more accessible and straightforward to apply. In psychological studies, researchers often use questionnaires or scales composed of multiple items to measure constructs of interest. As a result, missing values frequently occur at the item level, whereas data analyses are typically conducted at the scale (composite) level. However, properly addressing item-level missing data remains a common challenge for many applied psychologists, including researchers who are otherwise well experienced in handling missing data at the scale level. In this tutorial, we introduce six approaches for handling item-level …

Text Messages To Improve Young Child Diets: Results From A Cluster-Randomized Controlled Trial In Kanchanpur, Nepal, Kenda Cunningham, Sidney Cech, Aman Sen Gupta, Pooja Pandey Rana, Debbie Humphries, Edward A. Frongillo Jr. Ph.D.

Faculty Publications

The objective of this study was to test whether adding a text message campaign about the importance of eating eggs and other nutrition-related behaviours to an on-going package of large-scale, diverse social and behaviour change interventions would improve four types of nutrition-related knowledge and behaviour outcomes: child diets (egg consumption as the primary outcome), maternal diets, maternal nutrition knowledge, and maternal participation in additional interventions. The cluster-randomized controlled trial involved a repeat cross-sectional design, recruiting families with children 12–23 months of age at baseline and endline in one plains district of Nepal. Throughout the 1000-day period, 51 text messages were …

Impact Of Suaahara, An At-Scale Multisectoral Nutrition Programme, On Health Workers’ Maternal And Child Health, And Nutrition Knowledge And Skills In Nepal, Deependra K. Thapa, Edward A. Frongillo Jr. Ph.D., Shalini Suresh, Ramesh P. Adhikari, Bhim Pun, Karuna L. Shakya, Raj Mandal, Subir K. Kole, Kenda Cunningham

Faculty Publications

Suaahara, an at-scale multisectoral nutrition programme in Nepal, aimed to advance knowledge and skills of frontline health workers to improve the quality of nutrition and health services at health facility and community levels. This study assessed the impact of Suaahara interventions on knowledge and skills of health facility workers and Female Community Health Volunteers (FCHVs). The study used a quasi-experimental design in which four Suaahara intervention districts were compared with pair-matched comparison districts. One health facility worker and three FCHVs from each survey cluster were included. Baseline survey consisted of 93 health facility workers (2015) and 118 FCHVs (2012), and …

Characterization And Response To Exercise Training Of Hdl-Specific Phospholipid Efflux, Eric C. Leszcynski, Charles S. Schwartz, Kiani J.C. Jacobs, Prasun L. Dev, Sujoy Ghosh, Jeremy M. Robbins, Robert E. Gerszten, Anand Rohatgi, Timothy S. Collier, Robert J. Konard, Masaki Sato, Rafael Zubirán, Claude Bouchard, Edward B. Neufeld, Alan T. Remaley, Mark A. Sarzynski Facsm

Faculty Publications

The HDL-specific phospholipid efflux (HDL-SPE) assay is a novel cell-free measure of HDL function that is inversely associated with coronary artery disease. However, the effect of exercise training on HDL-SPE is unknown. The purpose of this study was to examine the effect of exercise training on HDL-SPE in a large, diverse cohort free of overt disease. Clinical and functional measures of HDL were taken before and after 20 weeks of endurance exercise training in 508 participants from the HERITAGE Family Study. Associations of HDL-SPE with HDL-related traits were examined using Pearson's correlations at baseline and following exercise training (significance: P …