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Accelerated Hatching Of Southern Leopard Frog (Rana Sphenocephala) Eggs In Response To The Presence Of A Crayfish (Procambarus Nigrocinctus) Predator, Daniel Saenz, James B. Johnson, Cory K. Adams, Gage H. Dayton Jan 2003

Accelerated Hatching Of Southern Leopard Frog (Rana Sphenocephala) Eggs In Response To The Presence Of A Crayfish (Procambarus Nigrocinctus) Predator, Daniel Saenz, James B. Johnson, Cory K. Adams, Gage H. Dayton

Faculty Publications

Phenotypic plasticity, such as morphological and behavioral changes in response to predators, is common in larval anurans. Less is known about inducible defenses in the embryonic stages of development. We investigated the predation risk imposed by crayfish (Procambarus nigrocinctus) on southern leopard frog (Rana sphenocephala) eggs aud whether crayfish presence induces a change in the timing of hatching of R. sphenocephala eggs. We found that crayfish significantly reduce the hatching success of R. sphenocephala eggs by eating them and that eggs hatch significantly faster in the presence of crayfish than when crayfish are not present. We …


The Influence Of Predator Threat On The Timing Of A Life-History Switch Point: Predator-Induced Hatching In The Southern Leopard Frog (Rana Sphenocephala), James B. Johnson, Daniel Saenz, Cory K. Adams, Richard N. Conner Jan 2003

The Influence Of Predator Threat On The Timing Of A Life-History Switch Point: Predator-Induced Hatching In The Southern Leopard Frog (Rana Sphenocephala), James B. Johnson, Daniel Saenz, Cory K. Adams, Richard N. Conner

Faculty Publications

We tested the hypotheses that potential egg predators, crayfish Procambarus nigrocinctus and dytiscid Cybister sp. larvae, would accelerate the timing of hatching and that a larval predator, dragonfly naiad Anax junius, would delay hatching in the southern leopard frog (Rana sphenocephala). We also tested the hypothesis that differences in response would be proportional to predator lethality. Our results indicate that our hypotheses were partially supported. The presence of an efficient egg predator (crayfish) induces hatching faster than a less efficient predator (dytiscid larvae). However, the presence of a larval predator (naiads) did not delay hatching. Eggs that …


Site‐Selective In Vivo Targeting Of Cytosine‐5 Dna Methylation By Zinc‐Finger Proteins, Christopher D. Carvin, Rebecca D. Parr, Michael P. Kladde Jan 2003

Site‐Selective In Vivo Targeting Of Cytosine‐5 Dna Methylation By Zinc‐Finger Proteins, Christopher D. Carvin, Rebecca D. Parr, Michael P. Kladde

Faculty Publications

Cytosine‐5 DNA methylation is a critical signal defining heritable epigenetic states of transcription. As aberrant methylation patterns often accompany disease states, the ability to target cytosine methylation to preselected regions could prove valuable in re‐establishing proper gene regulation. We employ the strategy of targeted gene methylation in yeast, which has a naturally unmethylated genome, selectively directing de novo DNA methylation via the fusion of C5 DNA methyltransferases to heterologous DNA‐binding proteins. The zinc‐finger proteins Zif268 and Zip53 can target DNA methylation by M.CviPI or M.SssI 5–52 nt from single zinc‐factor binding sites. Modification at specific GC (M.CviPI) or CG (M.SssI) …


Tetratricopeptide Repeat Motif-Mediated Hsc70-Msti1 Interaction Molecular Characterization Of The Critical Contacts For Successful Binding And Specificity*, Odutayo O. Odunuge, Judith A. Hornby, Chrisiane Bies, Richard Zimmermann, David J. Pugh, Gregory L. Blatch Jan 2003

Tetratricopeptide Repeat Motif-Mediated Hsc70-Msti1 Interaction Molecular Characterization Of The Critical Contacts For Successful Binding And Specificity*, Odutayo O. Odunuge, Judith A. Hornby, Chrisiane Bies, Richard Zimmermann, David J. Pugh, Gregory L. Blatch

Faculty Publications

Murine stress-inducible protein 1 (mSTI1) is a cochaperone that is homologous with the human Hsp70/ Hsp90-organizing protein (Hop). Guided by Hop structural data and sequence alignment analyses, we have used site-directed mutagenesis, co-precipitation assays, circular dichroism spectroscopy, steady-state fluorescence, and surface plasmon resonance spectroscopy to both qualitatively and quantitatively characterize the contacts necessary for the N-terminal tetratricopeptide repeat domain (TPR1) of mSTI1 to bind to heat shock cognate protein 70 (Hsc70) and to discriminate between Hsc70 and Hsp90. We have shown that substitutions in the first TPR motif of Lys8 or Asn12 did not affect binding of mSTI1 to Hsc70, …


The Aggressive Driving Behavior Scale: Developing A Self-Report Measure Of Unsafe Driving Practices, John M. Houston, Paul Harris Jan 2003

The Aggressive Driving Behavior Scale: Developing A Self-Report Measure Of Unsafe Driving Practices, John M. Houston, Paul Harris

Faculty Publications

The purpose of this study was to investigate the reliability and validity of a new 11-item measure of aggressive driving, the Aggressive Driving Behavior Scale, which focuses on behaviors rather than cognitions, emotions, or motivational states. Based on a sample of 200 undergraduates, 111 women and 89 men), the study examined the convergent validity of the new scale with measures of hostility, hypercompetitiveness, and aggressive thoughts and emotions experienced during driving. A principal component analysis of the Aggressive Driving Behavior Scale (alpha = .80) yielded two factors that form reliable subscales labeled Speeding and Conflict Behavior. As expected, the total …


Do Red-Cockaded Woodpeckers Select Cavity Trees Based On Chemical Composition Of Pine Resin?, Richard N. Conner Jan 2003

Do Red-Cockaded Woodpeckers Select Cavity Trees Based On Chemical Composition Of Pine Resin?, Richard N. Conner

Faculty Publications

We examined resin chemistry of loblolly (Pinus taeda) and shortleaf (P. echinata) pines selected as cavity trees by Red-cockaded Woodpeckers (Picoides borealis) in eastern Texas. We sampled resin from (1) pines selected by Red-cockaded Woodpeckers that contained naturally excavated active cavities, (2) pines selected by forest biologists that contained artificially installed cavity inserts and were actively being used by Red-cockaded Woodpeckers, and (3) control pines of similar age and appearance to the active cavity trees. We hypothesized that if woodpeckers are inducing a change in resin chemistry by excavating resin wells, this change should …


Effects Of Controlled Dog Hunting On Movements Of Female White-Tailed Deer, Christopher E. Comer Jan 2003

Effects Of Controlled Dog Hunting On Movements Of Female White-Tailed Deer, Christopher E. Comer

Faculty Publications

Understanding the responses of white-tailed deer (Odocoileus virginianus) to controlled dog hunting can aid in the effective implementation of canine-assisted population management strategies. We examined the 24-h diel movements of 13 radio-collared female deer exposed to dog hunting on the Savannah River Site (SRS) near Aiken, South Carolina, where regulated dog hunting has occurred since 1965. We compared diel home range size, rate of travel, and distance between extreme diel locations before, during, and after hunts from 14 September-14 December 2002. Die1 home range size (F2,91= 7.71, P < 0.001) and distance between extreme diel locations (F2,9l= 6.78, P = 0.002) on hunt day were greater than 10-day pre- and …


Economic Analysis Of Sequestering Carbon In Green Ash Forests In The Lower Mississippi River Valley, Ching Hsun Huang, Gary D. Kronrad, Shiaolin D. Cheng Jan 2003

Economic Analysis Of Sequestering Carbon In Green Ash Forests In The Lower Mississippi River Valley, Ching Hsun Huang, Gary D. Kronrad, Shiaolin D. Cheng

Faculty Publications

Since the U.S. is the largest emitter of carbon dioxide (CO2), it has become crucial to develop options that are both cost effective and supportive of sustainable development to reduce atmospheric CO2. Electric utility companies have the options of reducing their use of fossil fuels, switching to alternative energy sources, increasing efficiency, or offsetting carbon emissions. This study determined the cost and profitability of sequestering carbon in green ash plantations, and the number of tons of carbon that can be sequestered. The profitability of green ash is $2,342 and $3,645 per acre on site indices (measurement of soil quality) 65 …


Linking Landscape And Water Quality In The Mississippi River Basin For 200 Years, R. Eugene Turner, Nancy N. Rabalais Jan 2003

Linking Landscape And Water Quality In The Mississippi River Basin For 200 Years, R. Eugene Turner, Nancy N. Rabalais

Faculty Publications

Two centuries of land use in the Mississippi River watershed are reflected in the water quality of its streams and in the continental shelf ecosystem receiving its discharge. The most recent influence on nutrient loading-intense and widespread farming and especially fertilizer use-has had a more significant effect on water quality than has land drainage or the conversion of native vegetation to cropland and grazing pastures. The 200-year record of nutrient loading to offshore water is reflected in the paleoreconstructed record of plankton in dated sediments. This record illustrates that the development of fair, sustained management of inland ecosystems is linked …


Predicting The Response Of Gulf Of Mexico Hypoxia To Variations In Mississippi River Nitrogen Load, D Scavia, N N. Rabalais, R. Eugene Turner, D Justic, D Scavia Jan 2003

Predicting The Response Of Gulf Of Mexico Hypoxia To Variations In Mississippi River Nitrogen Load, D Scavia, N N. Rabalais, R. Eugene Turner, D Justic, D Scavia

Faculty Publications

The effects of nutrient loading from the Mississippi River basin on the areal extent of hypoxia in the northern Gulf of Mexico were examined using a novel application of a dissolved oxygen model for a river. The model, driven by river nitrogen load and a simple parameterization of ocean dynamics, reproduced 17 yr of observed hypoxia location and extent, subpycnocline oxygen consumption, and cross-pycnocline oxygen flux. With Monte Carlo analysis, we illustrate through hindcasts back to 1968 that extensive regions of low oxygen were not common before the mid-1970s. The Mississippi River Watershed/Gulf of Mexico Hypoxia Task Force set a …


Long-Term Observations Of A Harbor Seal Haul-Out Site In A Protected Cove In Casco Bay, Gulf Of Maine, David Harris Phd, Barbarai Lelli, Sat Gupta Jan 2003

Long-Term Observations Of A Harbor Seal Haul-Out Site In A Protected Cove In Casco Bay, Gulf Of Maine, David Harris Phd, Barbarai Lelli, Sat Gupta

Faculty Publications

We counted the numbers of seals hauled out at low tide on two near-shore ledges in a protected cove in Casco Bay, Gulf of Maine a minimum of 12 times per month, for four years starting in August 1997. The highest mean monthly counts were in August (molting season) and the lowest in either January or February. Counts during pupping season (May and June) were lower than during April or July. As no mother-pup pairs were observed, these ledges are molting but not pupping ledges. Time-series analysis revealed no overall trend in the number of seals present. but did show …


Hostile Environment Actions, Title Vii, And The Ada: The Limits Of The Copy-And-Paste Function, Lisa A. Eichhorn Jan 2003

Hostile Environment Actions, Title Vii, And The Ada: The Limits Of The Copy-And-Paste Function, Lisa A. Eichhorn

Faculty Publications

Two federal circuits, borrowing from Title VII jurisprudence, recently recognized a cause of action for a disability-based hostile environment under the Americans with Disabilities Act (ADA). Neither opinion, however, considered how the analysis of a disability-based hostile environment claim under the ADA might differ from that of a race- or sex-based hostile environment claim under Title VII. This Article examines the differing theories of equality underlying the two statutes and argues that, because the statutes prohibit discrimination in fundamentally different ways, courts must resist the temptation to copy and paste Title VII doctrine into ADA hostile environment opinions. This Article …


In Defense Of Geographic Disparity, Craig Allen Nard Jan 2003

In Defense Of Geographic Disparity, Craig Allen Nard

Faculty Publications

A response to Margo A. Bagley, Patently Unconstitutional: The Geographical Limitation on Prior Art in a Small World, 87 Minn. L. Rev. 679 (2003).


The Authority Of A Court To Order Disgorgement For Violations Of The Current Good Manufacturing Practices Requirement Of The Federal Food, Drug, And Cosmetic Act, Erika Lietzan, Elizabeth M. Walsh Jan 2003

The Authority Of A Court To Order Disgorgement For Violations Of The Current Good Manufacturing Practices Requirement Of The Federal Food, Drug, And Cosmetic Act, Erika Lietzan, Elizabeth M. Walsh

Faculty Publications

This article addresses the question as to whether a federal court has the authority to compel a pharmaceutical company to disgorge profits obtained from an alleged violation of the FDCA, specifically the failure of a pharmaceutical company to comply with current good manufacturing practices (GMPs). Section II of this article summarizes the article to which we are responding. In all fairness, it did not purport to be a full-blown defense, and we expect the agency's comprehensive defense of disgorgement would be considerably more detailed. Section III turns to the Sixth Circuit case on which FDA rests its argument for disgorgement, …


Matrix Heterogeneity And Host-Parasitoid Interactions In Space, James T. Cronin Jan 2003

Matrix Heterogeneity And Host-Parasitoid Interactions In Space, James T. Cronin

Faculty Publications

In this study, I experimentally examined how the landscape matrix influenced the movement, oviposition behavior, and spatial distribution of Anagrus columbi, a common egg parasitoid of the planthopper Prokelisia crocea. Both species exist among discrete patches of prairie cordgrass (Spartina pectinata), the sole host plant of P. crocea. Based on out-planted cordgrass pots bearing host eggs (to assess parasitism) or sticky leaves (traps for adult A. columbi), I found that the distribution of adult female A. columbi and pattern of ovipositions within a cordgrass patch were strongly matrix dependent. Female densities were 59% lower on the edge than interior of …


Matrix Composition Affects The Spatial Ecology Of A Prairie Planthopper, Kyle J. Haynes, James T. Cronin Jan 2003

Matrix Composition Affects The Spatial Ecology Of A Prairie Planthopper, Kyle J. Haynes, James T. Cronin

Faculty Publications

To date, there is a lack of well-controlled field experiments that disentangle the effects of the intervening matrix from other landscape variables (e.g., patch geography or quality) that might influence animal dispersal among patches. We performed a field experiment to investigate how the movement of a delphacid planthopper (Prokelisia crocea) among discrete patches of prairie cordgrass (Spartina pectinata) is affected by the composition of the matrix (mudflat, native nonhost grasses, and the introduced grass smooth brome [Bromus inermis]). Within each matrix type, marked planthoppers were released onto experimental cordgrass patches that were made identical in size, isolation, and host plant …


Influence Of The El Niño Southern Oscillation On Fire Regimes In The Florida Everglades, Brian Beckage, William J. Platt, Matthew G. Slocum, Bob Panko Jan 2003

Influence Of The El Niño Southern Oscillation On Fire Regimes In The Florida Everglades, Brian Beckage, William J. Platt, Matthew G. Slocum, Bob Panko

Faculty Publications

Disturbances that are strongly linked to global climatic cycles may occur in a regular, predictable manner that affects composition and distribution of ecological communities. The El Niño Southern Oscillation (ENSO) influences worldwide precipitation patterns and has occurred with regular periodicity over the last 130 000 years. We hypothesized that ENSO, through effects on local weather conditions, has influenced frequency and extent of fires within Everglades National Park (Florida, USA). Using data from 1948 to 1999, we found that the La Nina phase of ENSO was associated with decreased dry-season rainfall, lowered surface water levels, increased lightning strikes, more fires, and …


Use Of Common Weeds Of Rice As Hosts For The Rice Water Weevil (Coleoptera: Curculionidae), K. V. Tindall, M. J. Stout Jan 2003

Use Of Common Weeds Of Rice As Hosts For The Rice Water Weevil (Coleoptera: Curculionidae), K. V. Tindall, M. J. Stout

Faculty Publications

The rice water weevil, Lissorhoptrus oryzophilus Kuschel, is the most important insect pest in rice, Oryza sativa L., in the United States, Prior research indicates that rice water weevils feed primarily on monocotyledonous plants. Many monocot weeds occur in rice fields, but little is known about rice water weevil-weed interactions in rice. Host utilization of the rice water weevil was evaluated on rice, cultivar 'Cocodrie', and seven weeds commonly found in rice fields in preference and life cycle compatibility tests in the greenhouse. Barnyardgrass, Echinochloa crus-galli Beauv., yellow nutsedge, Cyperus esculentus L., broadleaf signalgrass, Brachiaria platyphylla Nash., and fall panicum, …


Natural Bovine Lentiviral Type 1 Infection In Holstein Dairy Cattle. I. Clinical, Serological, And Pathological Observations, T. G. Snider, B. F. Jenny, P. G. Hoyt, K. S. Coats, K. F. Graves, C. R. Cooper, R. W. Storts, D. G. Luther Jan 2003

Natural Bovine Lentiviral Type 1 Infection In Holstein Dairy Cattle. I. Clinical, Serological, And Pathological Observations, T. G. Snider, B. F. Jenny, P. G. Hoyt, K. S. Coats, K. F. Graves, C. R. Cooper, R. W. Storts, D. G. Luther

Faculty Publications

Clinical, serological, and pathological abnormalities observed in Holstein cows naturally infected with bovine lentivirus 1 bovine immunodeficiency virus (BIV) and other infections were progressive and most commonly associated with weight loss, lymphoid system deficiency, and behavioral changes. Clinical evidence of meningoencephalitis was dullness, stupor, and occasional head or nose pressing postures. The polymerase chain reactions associated the BIV provirus with the lesions in the central nervous system and lymphoid tissues. Multiple concurrent infections developed in retrovirally infected cows undergoing normal stresses associated with parturition and lactation. A major functional correlate of the lymphoreticular alterations was the development of multiple secondary …


Mobile Element-Based Assay For Human Gender Determination, Dale J. Hedges, Jerilyn A. Walker, Pauline A. Callinan, Jaiprakash G. Shewale, Sudhir K. Sinha, Mark A. Batzer Jan 2003

Mobile Element-Based Assay For Human Gender Determination, Dale J. Hedges, Jerilyn A. Walker, Pauline A. Callinan, Jaiprakash G. Shewale, Sudhir K. Sinha, Mark A. Batzer

Faculty Publications

No abstract provided.


Allelic Heterogeneity In Line-1 Retrotransposition Activity, Sheila M. Lutz, Bethaney J. Vincent, Haig H. Kazazian, Mark A. Batzer, John V. Moran Jan 2003

Allelic Heterogeneity In Line-1 Retrotransposition Activity, Sheila M. Lutz, Bethaney J. Vincent, Haig H. Kazazian, Mark A. Batzer, John V. Moran

Faculty Publications

De novo LINE-1 (long interspersed element-1, or L1) retrotransposition events are responsible for ∼1/1,000 disease-causing mutations in humans. Previously, L1.2 was identified as the likely progenitor of a mutagenic insertion in the factor VIII gene in a patient with hemophilia A. It subsequently was shown to be one of a small number of active L1s in the human genome. Here, we demonstrate that L1.2 is present at an intermediate insertion allele frequency in worldwide human populations and that common alleles (L1.2A and L1.2B) exhibit an ∼16-fold difference in their ability to retrotranspose in cultured human HeLa cells. Chimera analysis revealed …


Haplotypes In The Dystrophin Dna Segment Point To A Mosaic Origin Of Modern Human Diversity, Ewa Ziȩtkiewicz, Vania Yotova, Dominik Gehl, Tina Wambach, Isabel Arrieta, Mark Batzer, David E.C. Cole, Peter Hechtman, Feige Kaplan, David Modiano, Jean Paul Moisan, Roman Michalski, Damian Labuda Jan 2003

Haplotypes In The Dystrophin Dna Segment Point To A Mosaic Origin Of Modern Human Diversity, Ewa Ziȩtkiewicz, Vania Yotova, Dominik Gehl, Tina Wambach, Isabel Arrieta, Mark Batzer, David E.C. Cole, Peter Hechtman, Feige Kaplan, David Modiano, Jean Paul Moisan, Roman Michalski, Damian Labuda

Faculty Publications

Although Africa has played a central role in human evolutionary history, certain studies have suggested that not all contemporary human genetic diversity is of recent African origin. We investigated 35 simple polymorphic sites and one Tn microsatellite in an 8-kb segment of the dystrophin gene. We found 86 haplotypes in 1,343 chromosomes from around the world. Although a classical out-of-Africa topology was observed in trees based on the variant frequencies, the tree of haplotype sequences reveals three lineages accounting for present-day diversity. The proportion of new recombinants and the diversity of the Tn microsatellite were used to estimate the age …


Is Civil Authority Business Interruption Coverage A Soft Risk In The Post-9/11 World, Robert H. Jerry Ii Jan 2003

Is Civil Authority Business Interruption Coverage A Soft Risk In The Post-9/11 World, Robert H. Jerry Ii

Faculty Publications

Tthe question whether 9/11 has changed the insurance world cannot be answered simply In some respects, nothing is different, but it is difficult to be sanguine about this assessment. Terrorism is less predictable in terms of magnitude and frequency of loss, and this raises doubts about the capacity of the industry with respect to future events. Until the uncertainty with respect to the terrorism risk abates and markets stabilize, problems of cost and availability will persist. This, of course, has been true in other insurance sectors in the past, and temporary dislocations do not necessarily justify government intervention. If, however, …


Zymogram With Remazol Brilliant Blue-Labeled Micrococcus Lysodeikticus Cells For The Detection Of Lysozymes: Example Of A New Lysozyme Activity In Formosan Termite Defense Secretions, Markus Hardt, Youzhong Guo, Gregg Henderson, Roger A. Laine Jan 2003

Zymogram With Remazol Brilliant Blue-Labeled Micrococcus Lysodeikticus Cells For The Detection Of Lysozymes: Example Of A New Lysozyme Activity In Formosan Termite Defense Secretions, Markus Hardt, Youzhong Guo, Gregg Henderson, Roger A. Laine

Faculty Publications

No abstract provided.


Incremented Alkyl Derivatives Enhance Collision Induced Glycosidic Bond Cleavage In Mass Spectrometry Of Disaccharides, Sanford Mendonca, Richard B. Cole, Junhua Zhu, Yang Cai, Alfred D. French, Glenn P. Johnson, Roger A. Laine Jan 2003

Incremented Alkyl Derivatives Enhance Collision Induced Glycosidic Bond Cleavage In Mass Spectrometry Of Disaccharides, Sanford Mendonca, Richard B. Cole, Junhua Zhu, Yang Cai, Alfred D. French, Glenn P. Johnson, Roger A. Laine

Faculty Publications

Electrospray ionization and collision induced dissociation on a triple quadrupole mass spectrometer were used to determine the effect of spatial crowding of incremented alkyl groups of two anomeric pairs of peralkylated (methyl to pentyl) disaccharides (maltose/cellobiose and isomaltose/gentiobiose). Protonated molecules were generated which underwent extensive fragmentation under low energy conditions. For both the 1 → 4 and 1 → 6 α and β isomers, at comparable collision energies the methyl derivative exhibited the least fragmentation followed by ethyl, propyl, butyl, and pentyl. Collision energy is converted to rotational-vibrational modes in competition with bond cleavage, as represented by the slope of …


Diesel Exhaust Particles Exert Acute Effects On Airway Inflammation And Function In Murine Allergen Provocation Models, Minqi Hao, Stephania Comier, Meiying Wang, James J. Lee, Andre Nel Jan 2003

Diesel Exhaust Particles Exert Acute Effects On Airway Inflammation And Function In Murine Allergen Provocation Models, Minqi Hao, Stephania Comier, Meiying Wang, James J. Lee, Andre Nel

Faculty Publications

Background: Epidemiologic studies show that sudden surges in ambient particulate matter (PM) levels can trigger acute asthma exacerbations. Although diesel exhaust particles (DEPs) act as an adjuvant for allergic sensitization, this is a delayed response and does not explain acute PM effects on airway hyperreactivity (AHR). Objective: Our aim was to determine the acute effects of DEPs on AHR using a mouse model. Methods: Three protocols were developed, 2 of which require OVA sensitization, whereas the third was OVA independent. In the mild sensitization protocol BALB/c mice receive intraperitoneal OVA without alum and are then challenged with aerosolized OVA with …


Movement And Spatial Population Structure Of A Prairie Planthopper, James T. Cronin Jan 2003

Movement And Spatial Population Structure Of A Prairie Planthopper, James T. Cronin

Faculty Publications

The transfer of organisms among patches is a key process influencing the spatial structure and regional dynamics of a population; yet, detailed experimental studies of animal movement among patches are uncommon. I performed a series of mark-recapture studies to quantify the movement of a planthopper, Prokelisia crocea (Hemiptera: Delphacidae), among discrete patches of its host plant, prairie cordgrass (Spartina pectinata). Results from these dispersal studies were used to predict the natural distributions and to characterize the spatial population structure of P. crocea. Planthopper emigration loss per patch increased linearly with the density of female conspecifics and was nonlinearly related to …


A Genome-Wide Scan For Body Mass Index Among Nigerian Families, Adebowale Adeyemo, Amy Luke, Richard Cooper, Xiaodong Wu, Bamidele Tayo, Xiaofeng Zhu, Charles Rotimi, Nourdine Bouzekri, Ryk Ward Jan 2003

A Genome-Wide Scan For Body Mass Index Among Nigerian Families, Adebowale Adeyemo, Amy Luke, Richard Cooper, Xiaodong Wu, Bamidele Tayo, Xiaofeng Zhu, Charles Rotimi, Nourdine Bouzekri, Ryk Ward

Faculty Publications

Objective: Interest in mapping genetic variants that are associated with obesity remains high because of the increasing prevalence of obesity and its complications worldwide. Data on genetic determinants of obesity in African populations are rare. Research Methods and Procedures: We have undertaken a genome-wide scan for body mass index (BMI) in 182 Nigerian families that included 769 individuals. Results: The prevalence of obesity was only 5%, yet polygenic heritability for BMI was in the expected range (0.46 ± 0.07). Tandem repeat markers (402) were typed across the genome with an average map density of 9 cM. Pedigree-based analysis using a …


Influence Of Agronomic Hosts On The Susceptibility Of Helicoverpa Zea (Boddie) (Lepidoptera: Noctuidae) To Genetically Engineered And Non-Engineered Cottons, J. Gore, B. R. Leonard, R. H. Jones Jan 2003

Influence Of Agronomic Hosts On The Susceptibility Of Helicoverpa Zea (Boddie) (Lepidoptera: Noctuidae) To Genetically Engineered And Non-Engineered Cottons, J. Gore, B. R. Leonard, R. H. Jones

Faculty Publications

Field and laboratory studies evaluated the influence of selected crop hosts on Helicoverpa zea (Boddie) population dynamics in relation to genetically engineered Bt (Bollgard) and non-Bt cottons. Host specific H. zea colonies were initiated with a colony originally collected from sweet corn. The colony was allowed to complete one generation on meridic diet then split into cohorts and allowed to complete one generation on field corn, grain sorghum, soybean, cotton, or meridic diet in individual 29.5 ml plastic cups. During the first part of the study, larval developmental times, pupal weights, and survival were measured. H. zea survival was higher …


Terpene-Induced Morphological Changes To Exoskeleton Of Formosan Subterranean Termites (Isoptera: Rhinotermitidae): Toxic Effects Of Cis-Nerol, Betty C.R. Zhu, Gregg Henderson, Huixin Fei, Xiao Ying, Roger A. Laine Jan 2003

Terpene-Induced Morphological Changes To Exoskeleton Of Formosan Subterranean Termites (Isoptera: Rhinotermitidae): Toxic Effects Of Cis-Nerol, Betty C.R. Zhu, Gregg Henderson, Huixin Fei, Xiao Ying, Roger A. Laine

Faculty Publications

The terpenoid, cis-nerol was found to be highly toxic to the Formosan subterranean termite, Coptotermes formosanus Shiraki. Morphological abnormalities were observed in the exoskeleton including the spiracles and trichoid sensilla using scanning electron microscopy after exposure of termites to cis-nerol for 2 h. Proteins were found in a water-soluble fraction collected from the whole termite body exposed to cis-nerol for 60 min. It appears that terpenoids cause damage to cell membranes resulting in a significant loss of proteins.