Digital Commons Network^™

Users Aren’T (Necessarily) Lazy: Using Neurois To Explain Habituation To Security Warnings, Bonnie Brinton Anderson, Anthony Vance, Brock Kirwan, David Eargle, Seth Howard

Faculty Publications

Warning messages are one of the last lines of defense in information security, and are fundamental to users’ security interactions with technology. Unfortunately, research shows that users routinely ignore security warnings. A key contributor to this disregard is habituation, the diminishing of attention through frequent exposure. However, previous research has examined habituation indirectly by observing its influence on security behavior, rather than measuring habituation itself.

We contribute by using functional magnetic resonance imaging (fMRI) to directly observe habituation as it occurs in the brain. Our results show that with repeated exposure to warnings, neural activity in the visual processing centers …

Exploring Configurations Of Affordances: The Case Of Software Development, Aron Lindberg, James Gaskin, Nicholas Berente, Kalle Lyytinen

Faculty Publications

Affordances have been increasingly used in the information systems literature to account for the usage and effects of information technology. However, a review of the literature shows that the construct has remained nebulously defined, rarely used in anything but singular forms and with little consideration of context. This has resulted in a lack of cumulative research on affordances. We propose that affordances need to be considered not only individually, but also as configurations of multiple affordances. Through a sociomaterial sequence analysis of two software development teams – one waterfall and one agile - we build a framework for the study …

The United Nations Watercourses Convention On The Dawn Of Entry Into Force, Ryan Stoa

Faculty Publications

The United Nations Watercourses Convention entered into force in August 2014. Despite overwhelming support when signed in 1997, the ratification process has been slow. As a binding treaty, the Watercourses Convention provides hope that its provisions will articulate legal principles of transboundary water management capable of promoting cooperation and regional agreements. Despite entry into force, however, global support for the Watercourses Convention is weak, concurrent efforts to develop treaty regimes governing water resources create competition for resources and may obscure understandings of international water law, and the foundational principles of the Watercourses Convention remain ambiguous. These limitations are illustrated in …

Association Between Latent Toxoplasmosis And Major Depression, Generalised Anxiety Disorder And Panic Disorder In Human Adults, Shawn D. Gale, Bruce L. Brown, Andrew Berrett, Lance D. Erickson, Dawson W. Hedges

Faculty Publications

Latent infection with the apicomplexan Toxoplasma gondii (Nicolle et Manceaux, 1908) has been associated with schizophrenia, bipolar disorder and self-harm behaviour. However, the potential relationship between T. gondii immunoglobulin G antibody (IgG) seropositivity and generalised-anxiety disorder (GAD) and panic disorder (PD) has not been investigated. The associations between serum reactivity to T. gondii and major depressive disorder (MDD), GAD and PD were evaluated in a total sample of 1 846 adult participants between the ages of 20 and 39 years from the United States Center for Disease Control's National Health and Nutrition Examination Survey (NHANES). Approximately 16% of the overall …

The Functions Of The Executive At 75: An Invitation To Reconsider A Timeless Classic, Paul C. Godfrey, Joseph T. Mahoney

Faculty Publications

The year 2013 marks the 75th anniversary of the publication of Chester I. Barnard’s classic, The Functions of the Executive, a groundbreaking contribution to management theory. We maintain that Barnard’s work provides a valuable perspective on the causes and potential solutions to challenges facing capitalism, business, and management consequent to the scandals and financial crises of the early 21st century. We believe Barnard would see a systemic failure of the moral dimension of organization as a driver of these crises, and that management theory and practice need to focus on both the science and the aesthetics of management. We look …

Rearing Children In Love And Righteousness: Latitude, Limits, And Love, Craig H. Hart

Faculty Publications

The First Presidency (1999) counsels parents to “devote their best efforts to the teaching and rearing of their children in gospel principles which will keep them close to the Church,” and further states that “no other instrumentality can take [the home’s] place or fulfill its essential functions in carrying forward this God-given responsibility.” The proclamation on the family supports parents in magnifying their divinely designed responsibilities in the Father’s great plan of happiness (see Alma 42:8) by specifically identifying the principles that ultimately will make the most difference in their efforts.

How Does The Presence Of A Special Education Teacher Impact Co-Teachers’ Behavior In An Inclusive Classroom, Ryan O. Kellems Ph.D.

Faculty Publications

The majority of studies regarding co-teaching have primarily looked at what specific instructional practices and teacher characteristics are needed to make co-teaching an effective practice. In contrast, this study investigates how co-teaching affects a teacher’s particular teaching style and behavior. Of greatest interest is how a teacher’s use of instructional technology is impacted by the presence of a co-teacher. With many schools making inclusion a priority, the number of co-taught classes is increasing. In order for students to gain the most from classes that are co-taught, it is important that we first understand the factors that affect co-teachers. Once we …

A Mathematical Model Of Collagen Lattice Contraction, J. C. Dallon, Emily J. Evans, H Paul Erhlich

Faculty Publications

Two mathematical models for fibroblast-collagen interaction are proposed which reproduce qualitative features of fibroblast populated collagen lattice contraction in time. Both models are force based and model the cells as individual entities with discrete attachment sites however the collagen lattice is modeled differently for each model. In the collagen lattice model the lattice is more interconnected and formed by triangulating nodes to form the fibrous structure. In the collagen fiber model the nodes are not triangulated, are less interconnected, and the collagen fibers are modeled as a string of nodes. Both models suggest that the overall increase in stress of …

“And It Came To Pass . . .”: The Sociopolitical Events In The Book Of Mormon Leading To The Eighteenth Year Of The Reign Of The Judges, Dan Belnap, Daniel L. Belnap, Daniel Belnap, Dan Belnap

Faculty Publications

The period from the end of the seventeenth year of the reign of the judges to the beginning of the nineteenth year was a particularly unstable time in the history of the Nephite people. The amount of text Mormon devotes to it reveals the importance of this time period in their history. The crises that emerged during this time affected every Nephite, but they did not arise out of a vacuum. Instead, a number of prior social forces were at work and created an environment from which the tensions could find full form. This paper focuses on three primary forces: …

Lineage Ii Of Southeast Asian/American Denv-2 Is Associated With A Severe Dengue Outbreak In The Peruvian Amazon, Maya Williams, Sandra V. Mayer, William L. Johnson, Rubing Chen, Evgeniya Volkova, Stalin Vilcarromeor, Steven G. Widen, Thomas G. Wood, Luis Suarez-Ognio, Kanya C. Long, Katherine A. Hanley, Amy C. Morrison, Nikos Vasilakis, Eric S. Halsey

Faculty Publications

During 2010 and 2011, the Loreto region of Peru experienced a dengue outbreak of unprecedented magnitude and severity for the region. This outbreak coincided with the reappearance of dengue virus-2 (DENV-2) in Loreto after almost 8 years. Whole-genome sequence indicated that DENV-2 from the outbreak belonged to lineage II of the southeast Asian/American genotype and was most closely related to viruses circulating in Brazil during 2007 and 2008, whereas DENV-2 previously circulating in Loreto grouped with lineage I (DENV-2 strains circulating in South America since 1990). One amino acid substitution (NS5 A811V) in the 2010 and 2011 isolates resulted from …

Feeding Interactions Between Juvenile And Adult Flightless Cormorants., James Hayward, Libby C. Megna, Brianna G. Payne

Faculty Publications

We report observations on chick feedings by adult Flightless Cormorants Phalacrocorax harrisi, indicating that, contrary to the literature, the sequence of interaction is similar to that of other Pelecaniformes.

Peg3 Mutational Effects On Reproduction And Placenta-Specific Gene Families, Joomyeong Kim, Wesley D. Frey, Hongzhi He, Hana Kim, Muhammad B. Ekram, Arundhati Bakshi, Mohammad Faisal, Bambarendage P.U. Perera, An Ye, Ryoichi Teruyama

Faculty Publications

Peg3 (paternally expressed gene 3) is an imprinted gene encoding a DNA-binding protein. This gene plays important roles in controlling fetal growth rates and nurturing behaviors. In the current study, a new mutant mouse model has been generated to further characterize the functions of this DNA-binding protein. Besides known phenotypes, this new mutant model also revealed potential roles of Peg3 in mammalian reproduction. Female heterozygotes produce a much smaller number of mature oocytes than the wild-type littermates, resulting in reduced litter sizes. According to genome-wide expression analyses, several placenta-specific gene families are de-repressed in the brain of Peg3 heterozygous embryos, …

Factors Influencing Survival Of White-Tailed Deer Fawns In Coastal South Carolina, J. Clint Mccoy, Stephen S. Ditchkoff, Joshua B. Raglin, Bret A. Collier, Charles Ruth

Faculty Publications

The social and environmental pressures exerted on white-tailed deer Odocoileus virginianus in the southeastern United States are dynamic. Understanding factors that contribute to neonatal white-tailed deer mortality is vital to population management. To determine survival rates and causes of mortality, we captured and radio-monitored neonate white-tailed deer in the coastal plain of South Carolina. Using date of birth, mass, sex, age, and year as predictor variables, we created a candidate set of survival models to evaluate which factors influenced daily survival rates. We captured and monitored 210 fawns and recorded 68 total mortalities (32.3%). We recorded few mortalities in 2006 …

Comparative Genomics And Functional Analysis Of Rhamnose Catabolic Pathways And Regulons In Bacteria, Irina A. Rodionova, Xiaoqing Li, Vera Thiel, Sergey Stolyar, Krista Stanton, James K. Fredrickson, Donald A. Bryant, Andrei L. Osterman, Aaron A. Best, Dmitry A. Rodionov

Faculty Publications

L-rhamnose (Rha) is a deoxy-hexose sugar commonly found in nature. L-Rha catabolic pathways were previously characterized in various bacteria including Escherichia coli. Nevertheless, homology searches failed to recognize all the genes for the complete L Rha utilization pathways in diverse microbial species involved in biomass decomposition. Moreover, the regulatory mechanisms of L-Rha catabolism have remained unclear in most species. A comparative genomics approach was used to reconstruct the L-Rha catabolic pathways and transcriptional regulons in the phyla Actinobacteria, Bacteroidetes, Chloroflexi, Firmicutes, Proteobacteria, and Thermotogae. The reconstructed pathways include multiple novel enzymes and transporters involved in the utilization of L-Rha and …

Promoting Electrocatalytic Activity Of A Composite Sofc Cathode La0.8Sr0.2Mno3+Δ/Ce0.8Gd0.2O2-Δ With Molten Carbonates, Yunhui Gong, Xue Li, Lingling Zhang, Whitney Tharp, Changyong Qin, Kevin Huang

Faculty Publications

The effect of molten carbonates (MCs) on polarization resistance (R_P), a direct measure of oxygen reduction reaction (ORR) activity, of a composite La_0.8Sr_0.2MnO_3+δ/Ce_0.8Gd_0.2O_2-δ (LSM/GDC) solid oxide fuel cell (SOFC) cathode has been systematically investigated in this study over a temperature range of 550–650°C and partial pressure of oxygen (pO₂) span of 10⁻³ ∼ 1 atm. It is shown that the LSM/GDC cathode, either in the pristine or MC-modified states, can be generally modeled by two consecutive parallel circuits consisting of a resistance and a …

Measuring Changes In Tactile Sensitivity In The Hind Paw Of Mice Using An Electronic Von Frey Apparatus, Tijana Martinov, Madison Mack, Akilah Sykes, Devavani Chatterjea

Faculty Publications

Measuring inflammation-induced changes in thresholds of hind paw withdrawal from mechanical pressure is a useful technique to assess changes in pain perception in rodents. Withdrawal thresholds can be measured first at baseline and then following drug, venom, injury, allergen, or otherwise evoked inflammation by applying an accurate force on very specific areas of the skin. An electronic von Frey apparatus allows precise assessment of mouse hind paw withdrawal thresholds that are not limited by the available filament sizes in contrast to classical von Frey measurements. The ease and rapidity of measurements allow for incorporation of assessment of tactile sensitivity outcomes …

Model Combustion-Generated Particulate Matter Containing Persistent Free Radicals Redox Cycle To Produce Reactive Oxygen Species, Matthew A. Kelley, Valeria Y. Hebert, Taylor M. Thibeaux, Mackenzie A. Orchard, Farhana Hasan, Stephania A. Cormier, Paul T. Thevenot, Slawomir M. Lomnicki, Kurt J. Varner, Barry Dellinger, Brian M. Latimer, Tammy R. Dugas

Faculty Publications

Particulate matter (PM) is emitted during thermal decomposition of waste. During this process, aromatic compounds chemisorb to the surface of metal-oxide-containing PM, forming a surface-stabilized environmentally persistent free radical (EPFR). We hypothesized that EPFR-containing PM redox cycle to produce ROS and that this redox cycle is maintained in biological environments. To test our hypothesis, we incubated model EPFRs with the fluorescent probe dihydrorhodamine (DHR). Marked increases in DHR fluorescence were observed. Using a more specific assay, hydroxyl radicals ( •OH) were also detected, and their level was further increased by cotreatment with thiols or ascorbic acid (AA), known components of …

Unrecognized Coral Species Diversity Masks Differences In Functional Ecology, Jennifer N. Boulay, Michael E. Hellberg, Jorge Cortés, Iliana B. Baums

Faculty Publications

Porites corals are foundation species on Pacific reefs but a confused taxonomy hinders understanding of their ecosystem function and responses to climate change. Here, we show that what has been considered a single species in the eastern tropical Pacific, Porites lobata, includes a morphologically similar yet ecologically distinct species, Porites evermanni. While P. lobata reproduces mainly sexually, P. evermanni dominates in areas where triggerfish prey on bioeroding mussels living within the coral skeleton, thereby generating asexual coral fragments. These fragments proliferate in marginal habitat not colonized by P. lobata. The two Porites species also show a differential bleaching response despite …

Decay Of Interspecific Avian Flock Networks Along A Disturbance Gradient In Amazonia, Karl Mokross, Thomas B. Ryder, Marina Corrêa Côrtes, Jared D. Wolfe, Philip C. Stouffer

Faculty Publications

Our understanding of how anthropogenic habitat change shapes species interactions is in its infancy. This is in large part because analytical approaches such as network theory have only recently been applied to characterize complex community dynamics. Network models are a powerful tool for quantifying how ecological interactions are affected by habitat modification because they provide metrics that quantify community structure and function. Here, we examine how large-scale habitat alteration has affected ecological interactions among mixed-species flocking birds in Amazonian rainforest. These flocks provide a model system for investigating how habitat heterogeneity influences non-trophic interactions and the subsequent social structure of …

Exploring The " Dark Matter" Of A Mammalian Proteome By Protein Structure And Function Modeling, Michal Brylinski

Faculty Publications

Background: A growing body of evidence shows that gene products encoded by short open reading frames play key roles in numerous cellular processes. Yet, they are generally overlooked in genome assembly, escaping annotation because small protein-coding genes are difficult to predict computationally. Consequently, there are still a considerable number of small proteins whose functions are yet to be characterized.Results: To address this issue, we apply a collection of structural bioinformatics algorithms to infer molecular function of putative small proteins from the mouse proteome. Specifically, we construct 1,743 confident structure models of small proteins, which reveal a significant structural diversity with …

The Pseudomonas Syringaepv. Tomatotype Iii Effector Hopm1 Suppresses Arabidopsis Defenses Independent Of Suppressing Salicylic Acid Signaling And Of Targeting Atmin7, Anju Gangadharan, Mysore Venkatarau Sreerekha, Justin Whitehill, Jong Hyun Ham, David Mackey

Faculty Publications

Pseudomonas syringae pv tomato strain DC3000 (Pto) delivers several effector proteins promoting virulence, including HopM1, into plant cells via type III secretion. HopM1 contributes to full virulence of Pto by inducing degradation of Arabidopsis proteins, including AtMIN7, an ADP ribosylation factor-guanine nucleotide exchange factor. Pseudomonas syringae pv phaseolicola strain NPS3121 (Pph) lacks a functional HopM1 and elicits robust defenses in Arabidopsis thaliana, including accumulation of pathogenesis related 1 (PR-1) protein and deposition of callose-containing cell wall fortifications. We have examined the effects of heterologously expressed HopM1Pto on Pph-induced defenses. HopM1 suppresses Pphinduced PR-1 expression, a widely used marker for salicylic …

Social Withdrawal During Adolescence And Emerging Adulthood, Julie C. Bowker, Larry J. Nelson, Andrea Markovic, Stephanie Luster

Faculty Publications

Peer relationships are of central importance for healthy psychosocial development and functioning during childhood, adolescence, and adulthood. Peers provide unique opportunities for social-cognitive growth and the development and maintenance of social skills. They also serve as important sources of emotional and social support, can foster positive feelings about the self and others, and function protectively against the effects of interpersonal stressors (Rubin, Bukowski, & Parker, 2006). Without peer relationships, individuals might miss out on developmentally formative opportunities and experiences, such as acquiring certain socially competent skills and behaviors and forming intimate best friendships (Rubin, Coplan, & Bowker, 2009). It is …

Psychometric Properties Of The Adolescent Sleep Hygiene Scale, Amy Storfer-Isser, Monique K. Lebourgeois, John Harsh, Carolyn J. Tompsett, Susan Redline

Faculty Publications

This study evaluated the psychometric properties of the Adolescent Sleep Hygiene Scale (ASHS), a self-report measure assessing sleep practices theoretically important for optimal sleep. Data were collected on a community sample of 514 adolescents (16–19; 17.7 ± 0.4 years; 50% female) participating in the late adolescent examination of a longitudinal study on sleep and health. Sleep hygiene and daytime sleepiness were obtained from adolescent reports, behavior from caretaker reports, and sleep-wake estimation on weekdays from wrist actigraphy. Confirmatory factor analysis indicated the empirical and conceptually based factor structure were similar for six of the eight proposed sleep hygiene domains. Internal …

Social Regulation Of Male Reproductive Plasticity In An African Cichlid Fish, Karen P. Maruska, Russell D. Fernald

Faculty Publications

Social interactions with the outcome of a position in a dominance hierarchy can have profound effects on reproductive behavior and physiology, requiring animals to integrate environmental information with their internal physiological state; but how is salient information from the animal's dynamic social environment transformed into adaptive behavioral, physiological, and molecular-level changes? The African cichlid fish, Astatotilapia burtoni, is ideally suited to understand socially controlled reproductive plasticity because activity of the male reproductive (brainpituitary gonad) axis is tightly linked to social status. Males form hierarchies in which a small percentage of brightly colored dominant individuals have an active reproductive axis, defend …

Area-Wide Management Of Aedes Albopictus. Part 2: Gauging The Efficacy Of Traditional Integrated Pest Control Measures Against Urban Container Mosquitoes, Dina M. Fonseca, Isik Unlu, Taryn Crepeau, Ary Farajollahi, Sean P. Healy, Kristen Bartlett-Healy, Daniel Strickman, Randy Gaugler, George Hamilton, Daniel Kline, Gary G. Clark

Faculty Publications

Background: Aedes (Stegomyia) albopictus (Skuse) is an important disease vector and biting nuisance. During the 2009 active season, six ∼1000-parcel sites were studied, three in urban and three in suburban areas of New Jersey, United States, to examine the efficacy of standard integrated urban mosquito control strategies applied area wide. Active source reduction, larviciding, adulticiding and public education (source reduction through education) were implemented in one site in each county, an education-only approach was developed in a second site and a third site was used as an untreated experimental control. Populations were surveyed weekly with BG-Sentinel traps and ovitraps. Results: …

Formin-Based Control Of The Actin Cytoskeleton During Cytokinesis, K. Adam Bohnert, Alaina H. Willet, David R. Kovar, Kathleen L. Gould

Faculty Publications

Cytokinesis, the terminal event in the canonical cell cycle, physically separates daughter cells following mitosis. For cleavage to occur in many eukaryotes, a cytokinetic ring must assemble and constrict between divided genomes. Although dozens of different molecules localize to and participate within the cytokinetic ring, the core machinery comprises linear actin filaments. Accordingly, formins, which nucleate and elongate F-actin (filamentous actin) for the cytokinetic ring, are required for cytokinesis in diverse species. In the present article, we discuss specific modes of formin-based actin regulation during cell division and highlight emerging mechanisms and questions on this topic. © 2013 Biochemical Society.

Characterization Of Microsatellite Loci For A Threatened Species, The King Rail, Rallus Elegans, Using A Next-Generation Sequencing Protocol, Carol L. Brackett, James M. Maley, Robb T. Brumfield, Susan B. Mcrae

Faculty Publications

The King Rail Rallus elegans (Audubon) has experienced population declines of 4.6 % per year on average since the 1960s. Wetland loss, most severely affecting inland marshes, has significantly reduced this species' distribution to the coastal margins of its historic range. Polymorphic microsatellite markers were generated by 454 pyrosequencing of genomic DNA from King Rails, and Clapper Rails R. longirostris from Louisiana after AFLP enrichment and barcoding of restriction fragment cut sites across individuals. Of 1,419 microsatellite-containing sequences, 20 hypervariable microsatellite loci with up to 20 different alleles were identified at the alignment stage. We characterized nine loci, tested variability …

Evaluation Of Hand-Held Meters For Determination Of Hemolymph Lactate And Protein Concentrations In Red Swamp Crayfish Procambarus Clarkii, Christopher P. Bonvillain, D. Allen Rutherford, William E. Kelso, Christopher C. Green

Faculty Publications

We evaluated the accuracy of an Accutrend® lactate meter and a Reichert® Vet 360 temperature compensated refractometer for determining red swamp crayfish Procambarus clarkii (Girard, 1852) hemolymph lactate and protein concentrations, with results compared to measurements obtained from spectrophotometric analyses. Results from the lactate meter (R2 = 0.926) and refractometer (R2 = 0.830) both demonstrated strong relationships with spectrophotometer measurements, indicating that these instruments provide rapid, reliable, and economical methods for determining crayfish hemolymph lactate and protein concentrations. Both meters can provide on-site information to commercial crayfish farmers and processors to assess crayfish health and stress levels, and can also …

Phylogeny, Diversity, And Biogeography Of Southeast Asian Spiny Rats (Maxomys), Anang S. Achmadi, Jacob A. Esselstyn, Kevin C. Rowe, Ibnu Maryanto, M. T. Abdullah

Faculty Publications

Knowledge of the diversity and relationships of species in many groups of plants and animals in Southeast Asia is severely limited, preventing an integrative understanding of evolutionary and ecological processes in island archipelagos. We generated a 3-locus DNA sequence data set to estimate phylogenetic relationships among species and populations of Maxomys, a genus of rodents endemic to Southeast Asia. Our inclusion of Crunomys as a potential outgroup supported the monophyly of Crunomys, but the genus was deeply nested within Maxomys. Because of the relatively ancient divergences (mean uncorrected p-distances up to 0.15 in cytochrome-b sequences) among species of Maxomys and …

Hydrogen Evolution Reaction Measurements Of Dealloyed Porous Nicu, Kyla Koboski, Evan Nelsen, Jennifer R. Hampton

Faculty Publications

Porous metals are of interest for their high surface area and potential for enhanced catalytic behavior. Electrodeposited NiCu thin films with a range of compositions were electrochemically dealloyed to selectively remove the Cu component. The film structure, composition, and reactivity of these samples were characterized both before and after the dealloying step using scanning electron microscopy, energy-dispersive spectroscopy, and electrochemical measurements. The catalytic behavior of the dealloyed porous Ni samples towards the hydrogen evolution reaction was measured and compared to that of the as-deposited samples. The dealloyed samples were generally more reactive than their as-deposited counterparts at low overpotentials, making …