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Articles 5461 - 5490 of 10809
Full-Text Articles in Entire DC Network
Effect Of Blueberry Extract From Blueberry Pomace On The Microencapsulated Fish Oil, Juan Li, Kevin Mis Solval, Luis Alfaro, Jie Zhang, Arranee Chotiko, Jose Luis Brandao Delgado, Alexander Chouljenko, David Bankston, Peter J. Bechtel, Subramaniam Sathivel
Effect Of Blueberry Extract From Blueberry Pomace On The Microencapsulated Fish Oil, Juan Li, Kevin Mis Solval, Luis Alfaro, Jie Zhang, Arranee Chotiko, Jose Luis Brandao Delgado, Alexander Chouljenko, David Bankston, Peter J. Bechtel, Subramaniam Sathivel
Faculty Publications
The effect of the addition of blueberry extract (BE) obtained from blueberry pomace on lipid oxidation of pollock liver oil (PO) during microencapsulation was evaluated. An emulsion containing PO and BE (EBE) was prepared and spray dried in a pilot scale spray dryer. Thiobarbituric acids (TBARS) of EBE were lower (0.41mmol/kg oil) than that of control without BE (ENBE) (0.47mmol/kg oil). Also, TBARS value of 0.49mmol/kg oil for microencapsulated PO with BE (MBE) after spray drying was lower than that of microencapsulated PO without BE (MNBE) (0.57mmol/kg oil). MBE also had a lower TBARS value than that of MNBE after …
Sertraline Effects On Cerebrospinal Fluid Monoamines And Species-Typical Socioemotional Behavior Of Female Cynomolgus Monkeys, Carol A. Shively, Thomas C. Register, James Dee Higley, Stephanie L. Willard
Sertraline Effects On Cerebrospinal Fluid Monoamines And Species-Typical Socioemotional Behavior Of Female Cynomolgus Monkeys, Carol A. Shively, Thomas C. Register, James Dee Higley, Stephanie L. Willard
Faculty Publications
Rationale—Although widely prescribed, little is known about selective serotonin reuptake inhibitors (SSRIs) effects on social behavior and cerebrospinal fluid (CSF) monoamines in female primates.
Objective—To determine the effects of sertraline on agonistic and affiliative behavior.
Methods—21 adult female cynomolgus monkeys were housed in small, stable social groups, trained to participate in oral dosing, and began a 5-week cumulative dose response study. Serial doses of 0, 5, 10, 15, and 20 mg/kg of sertraline were administered orally for one week each. Behavior was recorded daily during 10-minute observations before and 4 hours after dosing. On the 7th day of dosing, circulating …
Small Data Surveillance V. Big Data Cybersurveillance, Margaret Hu
Small Data Surveillance V. Big Data Cybersurveillance, Margaret Hu
Faculty Publications
This Article highlights some of the critical distinctions between small data surveillance and big data cybersurveillance as methods of intelligence gathering. Specifically, in the intelligence context, it appears that "collect-it-all" tools in a big data world can now potentially facilitate the construction, by the intelligence community, of other individuals' digital avatars. The digital avatar can be understood as a virtual representation of our digital selves and may serve as a potential proxy for an actual person. This construction may be enabled through processes such as the data fusion of biometric and biographic data, or the digital data fusion of the …
Pastors As Gatekeepers: Congregational Encounters With Mental Health And Substance Abuse Issues, Curtis J. Vanderwaal, Andrea Opei, Edwin I. Hernandez
Pastors As Gatekeepers: Congregational Encounters With Mental Health And Substance Abuse Issues, Curtis J. Vanderwaal, Andrea Opei, Edwin I. Hernandez
Faculty Publications
The vocation of a pastor is to care for the spiritual needs of a congregation and community. However, as many clergy know well, pastoral care is multifaceted and complex. For example, one of the hats that pastors frequently wear is that of pastoral counselor. Although pastors have traditionally offered support and pastoral care to congregants, they are beginning to spend more hours counseling both congregants and community members. One study indicated that pastors were spending time in pastoral counseling equivalent to that of marriage and family therapists in private practice.1 The same study showed that pastors are encountering persons and …
Multicountry Prospective Clinical Evaluation Of Two Enzyme-Linked Immunosorbent Assays And Two Rapid Diagnostic Tests For Diagnosing Dengue Fever, Subhamoy Pal, Allison Dauner, Andrea Valks, Brett M. Forshey, Kanya C. Long, Butsaya Thaisomboonsuk, Gloria Sierra, Victor Picos, Sara Talmage, Amy C. Morrison, Eric S. Halsey, Guillermo Comach, Chadwick Yasuda, Michael Loeffelholz, Richard G. Jarman, Stefan Fernandez, Ung Sam An, Tadeusz J. Kochel, Louis E. Jasper, Shuenn-Jue L. Wu
Multicountry Prospective Clinical Evaluation Of Two Enzyme-Linked Immunosorbent Assays And Two Rapid Diagnostic Tests For Diagnosing Dengue Fever, Subhamoy Pal, Allison Dauner, Andrea Valks, Brett M. Forshey, Kanya C. Long, Butsaya Thaisomboonsuk, Gloria Sierra, Victor Picos, Sara Talmage, Amy C. Morrison, Eric S. Halsey, Guillermo Comach, Chadwick Yasuda, Michael Loeffelholz, Richard G. Jarman, Stefan Fernandez, Ung Sam An, Tadeusz J. Kochel, Louis E. Jasper, Shuenn-Jue L. Wu
Faculty Publications
We evaluated four dengue diagnostic devices from Alere, including the SD Bioline Dengue Duo (nonstructural [NS] 1 Ag and IgG/IgM), the Panbio Dengue Duo Cassette (IgM/IgG) rapid diagnostic tests (RDTs), and the Panbio dengue IgM and IgG capture enzyme-linked immunosorbent assays (ELISAs) in a prospective, controlled, multicenter study in Peru, Venezuela, Cambodia, and the United States, using samples from 1,021 febrile individuals. Archived, well-characterized samples from an additional 135 febrile individuals from Thailand were also used. Reference testing was performed on all samples using an algorithm involving virus isolation, in-house IgM and IgG capture ELISAs, and plaque reduction neutralization tests …
Immediate Chromatin Immunoprecipitation And On-Bead Quantitative Pcr Analysis: A Versatile And Rapid Chip Procedure, Kayla M. Harmeyer, Paul F. South, Brett Bishop, Joe Ogas, Scott D. Briggs
Immediate Chromatin Immunoprecipitation And On-Bead Quantitative Pcr Analysis: A Versatile And Rapid Chip Procedure, Kayla M. Harmeyer, Paul F. South, Brett Bishop, Joe Ogas, Scott D. Briggs
Faculty Publications
© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. Genome-wide chromatin immunoprecipitation (ChIP) studies have brought significant insight into the genomic localization of chromatin-associated proteins and histone modifications. The large amount of data generated by these analyses, however, require approaches that enable rapid validation and analysis of biological relevance. Furthermore, there are still protein and modification targets that are difficult to detect using standard ChIP methods. To address these issues, we developed an immediate chromatin immunoprecipitation procedure which we call ZipChip. ZipChip significantly reduces the time and increases sensitivity allowing for rapid screening of …
Marine Sequestration Of Carbon In Bacterial Metabolites, Oliver J. Lechtenfeld, Norbert Hertkorn, Yuan Shen, Matthias Witt, Ronald Benner
Marine Sequestration Of Carbon In Bacterial Metabolites, Oliver J. Lechtenfeld, Norbert Hertkorn, Yuan Shen, Matthias Witt, Ronald Benner
Faculty Publications
Linking microbial metabolomics and carbon sequestration in the ocean via refractory organic molecules has been hampered by the chemical complexity of dissolved organic matter (DOM). Here, using bioassay experiments and ultra-high resolution metabolic profiling, we demonstrate that marine bacteria rapidly utilize simple organic molecules and produce exometabolites of remarkable molecular and structural diversity. Bacterial DOM is similar in chemical composition and structural complexity to naturally occurring DOM in sea water. An appreciable fraction of bacterial DOM has molecular and structural properties that are consistent with those of refractory molecules in the ocean, indicating a dominant role for bacteria in shaping …
Insights Into Ultrasonic Release From Eliposomes, Marjan Javadi, William G. Pitt
Insights Into Ultrasonic Release From Eliposomes, Marjan Javadi, William G. Pitt
Faculty Publications
A novel nanosized liposomal carrier was prepared consisting of perfluorocarbon emulsion droplet(s) encapsulated inside a liposome, which is called an eLiposome. This 200-nm construct is useful for acoustically activated drug delivery because ultrasound causes the emulsion droplet to expand from liquid to gas, which expansion ruptures the eLiposome bilayer and releases the internal contents. This study focuses on the parameters that influence control of the release of calcein (a model drug), including ultrasound amplitude, insonation time, and perfluorocarbon vapor pressure as a function of temperature and composition. The results show that calcein release increases as the ultrasound amplitude or insonation …
Human Adipose Tissue As A Reservoir For Memory Cd4+ T Cells And Hiv, Jacob Couturier, James W. Suliburk, Jeremy M. Brown, David J. Luke, Neeti Agarwal, Xiaoying Yu, Chi Nguyen, Dinakar Iyer, Claudia A. Kozinetz, Paul A. Overbeek, Michael L. Metzker, Ashok Balasubramanyam, Dorothy E. Lewis
Human Adipose Tissue As A Reservoir For Memory Cd4+ T Cells And Hiv, Jacob Couturier, James W. Suliburk, Jeremy M. Brown, David J. Luke, Neeti Agarwal, Xiaoying Yu, Chi Nguyen, Dinakar Iyer, Claudia A. Kozinetz, Paul A. Overbeek, Michael L. Metzker, Ashok Balasubramanyam, Dorothy E. Lewis
Faculty Publications
Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. Objective: The objective of this study is to determine whether adipose tissue functions as a reservoir for HIV-1. Design: We examined memory CD4+ T cells and HIV DNA in adipose tissue-stromal vascular fraction (AT-SVF) of five patients [four antiretroviral therapy (ART)-treated and one untreated]. To determine whether adipocytes stimulate CD4+ T cells and regulate HIV production, primary human adipose cells were cocultured with HIV-infected CD4+ T cells. Methods: AT-SVF T cells were studied by flow cytometry, and AT-SVF HIV DNA (Gag and Env) was examined by nested PCR and sequence …
Human Adipose Tissue As A Reservoir For Memory Cd4(+) T Cells And Hiv, J Couturier, J W. Suliburk, J M. Brown, D J. Luke, J Couturier, X Y. Yu, C Nguyen, D Iyer, C A. Kozinetz, P A. Overbeek, M L. Metzker, A Balasubramanyam, D E. Lewis
Human Adipose Tissue As A Reservoir For Memory Cd4(+) T Cells And Hiv, J Couturier, J W. Suliburk, J M. Brown, D J. Luke, J Couturier, X Y. Yu, C Nguyen, D Iyer, C A. Kozinetz, P A. Overbeek, M L. Metzker, A Balasubramanyam, D E. Lewis
Faculty Publications
Objective: The objective of this study is to determine whether adipose tissue functions as a reservoir for HIV-1. Design: We examined memory CD4(+) T cells and HIV DNA in adipose tissue-stromal vascular fraction (AT-SVF) of five patients [four antiretroviral therapy (ART)-treated and one untreated]. To determine whether adipocytes stimulate CD4(+) T cells and regulate HIV production, primary human adipose cells were cocultured with HIV-infected CD4(+) T cells. Methods: AT-SVF T cells were studied by flow cytometry, and AT-SVF HIV DNA (Gag and Env) was examined by nested PCR and sequence analyses. CD4(+) T-cell activation and HIV production were measured by …
Human Adipose Tissue As A Reservoir For Memory Cd4(+) T Cells And Hiv, J Couturier, J W. Suliburk, J M. Brown, D J. Luke, J Couturier, X Y. Yu, C Nguyen, D Iyer, C A. Kozinetz, P A. Overbeek, M L. Metzker, A Balasubramanyam, D E. Lewis
Human Adipose Tissue As A Reservoir For Memory Cd4(+) T Cells And Hiv, J Couturier, J W. Suliburk, J M. Brown, D J. Luke, J Couturier, X Y. Yu, C Nguyen, D Iyer, C A. Kozinetz, P A. Overbeek, M L. Metzker, A Balasubramanyam, D E. Lewis
Faculty Publications
Objective: The objective of this study is to determine whether adipose tissue functions as a reservoir for HIV-1. Design: We examined memory CD4(+) T cells and HIV DNA in adipose tissue-stromal vascular fraction (AT-SVF) of five patients [four antiretroviral therapy (ART)-treated and one untreated]. To determine whether adipocytes stimulate CD4(+) T cells and regulate HIV production, primary human adipose cells were cocultured with HIV-infected CD4(+) T cells. Methods: AT-SVF T cells were studied by flow cytometry, and AT-SVF HIV DNA (Gag and Env) was examined by nested PCR and sequence analyses. CD4(+) T-cell activation and HIV production were measured by …
Draft Genome Sequence Of The Phenazine-Producing Pseudomonas Fluorescens Strain 2-79, Kai Nesemann, Susanna A. Braus-Stromeyer, Andrea Thuermer, Rolf Daniel, Dmitri V. Mavrodi, Linda S. Thomashow, David M. Weller, Gerard H. Braus
Draft Genome Sequence Of The Phenazine-Producing Pseudomonas Fluorescens Strain 2-79, Kai Nesemann, Susanna A. Braus-Stromeyer, Andrea Thuermer, Rolf Daniel, Dmitri V. Mavrodi, Linda S. Thomashow, David M. Weller, Gerard H. Braus
Faculty Publications
Pseudomonas fluorescens strain 2-79, a natural isolate of the rhizosphere of wheat (Triticum aestivum L.), possesses antagonistic potential toward several fungal pathogens. We report the draft genome sequnce of strain 2-79, which comprises 5,674 protein-coding sequences.
Loneliness And Social Isolation As Risk Factors For Mortality: A Meta-Analytic Review, Julianne Holt-Lunstad, Timothy B. Smith, Mark Baker, Tyler Harris, David Stephenson
Loneliness And Social Isolation As Risk Factors For Mortality: A Meta-Analytic Review, Julianne Holt-Lunstad, Timothy B. Smith, Mark Baker, Tyler Harris, David Stephenson
Faculty Publications
Actual and perceived social isolation are both associated with increased risk for early mortality. The objective of this meta-analytic review is to establish the overall and relative magnitude of social isolation and loneliness and examine possible moderators. A literature search of studies (January 1980 to February 2014) was conducted using MEDLINE, CINAHL, PsycINFO, Social Work Abstracts, and Google Scholar. The included studies provide quantitative data on mortality as affected by loneliness, social isolation, or living alone. Across studies that statistically controlled for a variety of possible confounds, the independent random effects weighted average effect sizes for social isolation OR = …
Sequencing, Identification And Mapping Of Primed L1 Elements (Simple) Reveals Significant Variation In Full Length L1 Elements Between Individuals, Vincent A. Streva, Vallmer E. Jordan, Sara Linker, Dale J. Hedges, Mark A. Batzer, Prescott L. Deininger
Sequencing, Identification And Mapping Of Primed L1 Elements (Simple) Reveals Significant Variation In Full Length L1 Elements Between Individuals, Vincent A. Streva, Vallmer E. Jordan, Sara Linker, Dale J. Hedges, Mark A. Batzer, Prescott L. Deininger
Faculty Publications
© Streva et al. Background: There are over a half a million copies of L1 retroelements in the human genome which are responsible for as much as 0.5% of new human genetic diseases. Most new L1 inserts arise from young source elements that are polymorphic in the human genome. Highly active polymorphic "hot" L1 source elements have been shown to be capable of extremely high levels of mobilization and result in numerous instances of disease. Additionally, hot polymorphic L1s have been described to be highly active within numerous cancer genomes. These hot L1s result in mutagenesis by insertion of new …
A Meta-Analysis Of Gene Expression Signatures Of Blood Pressure And Hypertension, Tianxiao Huan, Tõnu Esko, Marjolein J. Peters, Luke C. Pilling, Katharina Schramm, Claudia Schurmann, Brian H. Chen, Chunyu Liu, Roby Joehanes, Andrew D. Johnson, Chen Yao, Sai Xia Ying, Paul Courchesne, Lili Milani, Nalini Raghavachari, Richard Wang, Poching Liu, Eva Reinmaa, Abbas Dehghan, Albert Hofman, André G. Uitterlinden, Dena G. Hernandez, Stefania Bandinelli, Andrew Singleton, David Melzer, Andres Metspalu, Maren Carstensen, Harald Grallert, Christian Herder, Thomas Meitinger, Annette Peters, Michael Roden, Melanie Waldenberger
A Meta-Analysis Of Gene Expression Signatures Of Blood Pressure And Hypertension, Tianxiao Huan, Tõnu Esko, Marjolein J. Peters, Luke C. Pilling, Katharina Schramm, Claudia Schurmann, Brian H. Chen, Chunyu Liu, Roby Joehanes, Andrew D. Johnson, Chen Yao, Sai Xia Ying, Paul Courchesne, Lili Milani, Nalini Raghavachari, Richard Wang, Poching Liu, Eva Reinmaa, Abbas Dehghan, Albert Hofman, André G. Uitterlinden, Dena G. Hernandez, Stefania Bandinelli, Andrew Singleton, David Melzer, Andres Metspalu, Maren Carstensen, Harald Grallert, Christian Herder, Thomas Meitinger, Annette Peters, Michael Roden, Melanie Waldenberger
Faculty Publications
Genome-wide association studies (GWAS) have uncovered numerous genetic variants (SNPs) that are associated with blood pressure (BP). Genetic variants may lead to BP changes by acting on intermediate molecular phenotypes such as coded protein sequence or gene expression, which in turn affect BP variability. Therefore, characterizing genes whose expression is associated with BP may reveal cellular processes involved in BP regulation and uncover how transcripts mediate genetic and environmental effects on BP variability. A meta-analysis of results from six studies of global gene expression profiles of BP and hypertension in whole blood was performed in 7017 individuals who were not …
Yy1 Gene Dosage Effect And Bi-Allelic Expression Of Peg3, Bambarendage P.U. Perera, Ryoichi Teruyama, Joomyeong Kim
Yy1 Gene Dosage Effect And Bi-Allelic Expression Of Peg3, Bambarendage P.U. Perera, Ryoichi Teruyama, Joomyeong Kim
Faculty Publications
© 2015 Perera et al. In the current study, we tested the in vivo effects of Yy1 gene dosage on the Peg3 imprinted domain with various breeding schemes utilizing two sets of mutant alleles. The results indicated that a half dosage of Yy1 coincides with the up-regulation of Peg3 and Zim1, suggesting a repressor role of Yy1 in this imprinted domain. This repressor role of Yy1 is consistent with the observations derived from previous in vitro studies. The current study also provided an unexpected observation that the maternal allele of Peg3 is also normally expressed, and thus the expression of …
A Sequence Variant In Human Kalrn Impairs Protein Function And Coincides With Reduced Cortical Thickness, Derin J. Cobia, Theron A. Russell, Katherine D. Blizinsky, Michael Cahill, Zhong Xie, Robert A. Sweet, Jubao Duan, Pablo V. Gejman, Lei Wang, John G. Csernansky, Peter Penzes
A Sequence Variant In Human Kalrn Impairs Protein Function And Coincides With Reduced Cortical Thickness, Derin J. Cobia, Theron A. Russell, Katherine D. Blizinsky, Michael Cahill, Zhong Xie, Robert A. Sweet, Jubao Duan, Pablo V. Gejman, Lei Wang, John G. Csernansky, Peter Penzes
Faculty Publications
Dendritic spine pathology is a key feature of several neuropsychiatric disorders. The Rac1 guanine nucleotide exchange factor kalirin-7 is critical for spine morphogenesis on cortical pyramidal neurons. Here we identify a rare coding variant in the KALRN gene region that encodes the catalytic domain, in a schizophrenia patient and his sibling with major depressive disorder. The D1338N substitution significantly diminished the protein's ability catalyze the activation of Rac1. Contrary to wild-type kalirin-7, kalirin-7-D1338N failed to increase spine size and density. Both subjects carrying the polymorphism displayed reduced cortical volume in the superior temporal sulcus (STS), a region implicated in schizophrenia. …
Analysis Of The Radiation-Damage-Free X-Ray Structure Of Photosystem Ii In Light Of Exafs And Qm/Mm Data, Mikhail Askerka, David J. Vinyard, Jimin Wang, Gary W. Brudvig, Victor S. Batista
Analysis Of The Radiation-Damage-Free X-Ray Structure Of Photosystem Ii In Light Of Exafs And Qm/Mm Data, Mikhail Askerka, David J. Vinyard, Jimin Wang, Gary W. Brudvig, Victor S. Batista
Faculty Publications
© 2015 American Chemical Society. A recent femtosecond X-ray diffraction study produced the first high-resolution structural model of the oxygen-evolving complex of photosystem II that is free of radiation-induced manganese reduction (Protein Data Bank entries 4UB6 and 4UB8). We find, however, that the model does not match extended X-ray absorption fine structure and QM/MM data for the S1 state. This is attributed to uncertainty about the positions of oxygen atoms that remain partially unresolved, even at 1.95 Å resolution, next to the heavy manganese centers. In addition, the photosystem II crystals may contain significant amounts of the S0 state, because …
Engineering Nanoparticles To Silence Bacterial Communication, Kristen P. Miller, Lei Wang, Yung-Pin Chen, Perry J. Pellechia, Brian C. Benicewicz, Alan W. Decho
Engineering Nanoparticles To Silence Bacterial Communication, Kristen P. Miller, Lei Wang, Yung-Pin Chen, Perry J. Pellechia, Brian C. Benicewicz, Alan W. Decho
Faculty Publications
The alarming spread of bacterial resistance to traditional antibiotics has warranted the study of alternative antimicrobial agents. Quorum sensing (QS) is a chemical cell-to-cell communication mechanism utilized by bacteria to coordinate group behaviors and establish infections. QS is integral to bacterial survival, and therefore provides a unique target for antimicrobial therapy. In this study, silicon dioxide nanoparticles (Si-NP) were engineered to target the signaling molecules [i.e., acylhomoserine lactones (HSLs)] used for QS in order to halt bacterial communication. Specifically, when Si-NP were surface functionalized with β-cyclodextrin (β-CD), then added to cultures of bacteria (Vibrio fischeri), whose luminous output depends upon …
Elevated Hypertension Risk For African-Origin Populations In Biracial Societies: Modeling The Epidemiologic Transition Study, Richard S. Cooper, Terrence E. Forrester, Jacob Plange-Rhule, Pascal Bovet, Estelle V. Lambert, Lara R. Dugas, Kathryn E. Cargill, Ramon A. Durazo-Arvizu, David A. Shoham, Liping Tong, Guichan Cao, Amy Luke
Elevated Hypertension Risk For African-Origin Populations In Biracial Societies: Modeling The Epidemiologic Transition Study, Richard S. Cooper, Terrence E. Forrester, Jacob Plange-Rhule, Pascal Bovet, Estelle V. Lambert, Lara R. Dugas, Kathryn E. Cargill, Ramon A. Durazo-Arvizu, David A. Shoham, Liping Tong, Guichan Cao, Amy Luke
Faculty Publications
OBJECTIVES:: Blood pressures in persons of African descent exceed those of other racial/ethnic groups in the United States. Whether this trait is attributable to the genetic factors in African-origin populations, or a result of inadequately measured environmental exposures, such as racial discrimination, is not known. To study this question, we conducted a multisite comparative study of communities in the African diaspora, drawn from metropolitan Chicago, Kingston, Jamaica, rural Ghana, Cape Town, South Africa, and the Seychelles. METHODS:: At each site, 500 participants between the age of 25 and 49 years, with approximately equal sex balance, were enrolled for a longitudinal …
Concerted Motions Networking Pores And Distant Ferroxidase Centers Enable Bacterioferritin Function And Iron Traffic, Huili Yao, Huan Rui, Ritesh Kumar, Kate Eshelman, Scott Lovell, Kevin P. Battaile, Wonpil Im, Mario Rivera
Concerted Motions Networking Pores And Distant Ferroxidase Centers Enable Bacterioferritin Function And Iron Traffic, Huili Yao, Huan Rui, Ritesh Kumar, Kate Eshelman, Scott Lovell, Kevin P. Battaile, Wonpil Im, Mario Rivera
Faculty Publications
© 2015 American Chemical Society. X-ray crystallography, molecular dynamics (MD) simulations, and biochemistry were utilized to investigate the effect of introducing hydrophobic interactions in the 4-fold (N148L and Q151L) and B-pores (D34F) of Pseudomonas aeruginosa bacterioferritin B (BfrB) on BfrB function. The structures show only local structural perturbations and confirm the anticipated hydrophobic interactions. Surprisingly, structures obtained after soaking crystals in Fe2+-containing crystallization solution revealed that although iron loads into the ferroxidase centers of the mutants, the side chains of ferroxidase ligands E51 and H130 do not reorganize to bind the iron ions, as is seen in the wt BfrB …
Strain-Dependence Of The Structure And Ferroic Properties Of Epitaxial Ni1 - Xti1 - Yo3 Thin Films Grown On Sapphire Substrates, Tamas Varga, Timothy C. Droubay, Mark E. Bowden, Sean A. Stephens, Sandeep Manandhar, Vaithiyalingam Shutthanandan, Robert J. Colby, Dehong Hu, William A. Shelton, Scott A. Chambers
Strain-Dependence Of The Structure And Ferroic Properties Of Epitaxial Ni1 - Xti1 - Yo3 Thin Films Grown On Sapphire Substrates, Tamas Varga, Timothy C. Droubay, Mark E. Bowden, Sean A. Stephens, Sandeep Manandhar, Vaithiyalingam Shutthanandan, Robert J. Colby, Dehong Hu, William A. Shelton, Scott A. Chambers
Faculty Publications
Polarization-induced weak ferromagnetism has been predicted a few years back in compounds MTiO3 (M = Fe, Mn, Ni) (Fennie, 2008). We set out to stabilize this metastable, distorted perovskite structure by growing NiTiO3 epitaxially on sapphire Al2O3 (001) substrate, and to control the polar and magnetic properties via strain. Epitaxial Ni1 - xTi1 - yO3 films of different Ni/Ti ratios and thicknesses were deposited on Al2O3 substrates by pulsed laser deposition at different temperatures, and characterized using several techniques. The effect of film thickness, deposition temperature, and film stoichiometry on lattice strain, film structure, and physical properties was investigated. Our …
The Structural Basis For Specificity In Lipoxygenase Catalysis, Marcia E. Newcomer, Alan R. Brash
The Structural Basis For Specificity In Lipoxygenase Catalysis, Marcia E. Newcomer, Alan R. Brash
Faculty Publications
© 2014 The Protein Society. Many intriguing facets of lipoxygenase (LOX) catalysis are open to a detailed structural analysis. Polyunsaturated fatty acids with two to six double bonds are oxygenated precisely on a particular carbon, typically forming a single chiral fatty acid hydroperoxide product. Molecular oxygen is not bound or liganded during catalysis, yet it is directed precisely to one position and one stereo configuration on the reacting fatty acid. The transformations proceed upon exposure of substrate to enzyme in the presence of O2 (RH + O2 → ROOH), so it has proved challenging to capture the precise mode of …
Examining Evolutionary Relationships And Shifts In Depth Preferences In Batfishes (Lophiiformes: Ogcocephalidae), Valerie Derouen, William B. Ludt, Hsuan Ching Ho, Prosanta Chakrabarty
Examining Evolutionary Relationships And Shifts In Depth Preferences In Batfishes (Lophiiformes: Ogcocephalidae), Valerie Derouen, William B. Ludt, Hsuan Ching Ho, Prosanta Chakrabarty
Faculty Publications
© 2014 Elsevier Inc. Batfishes (Ogcocephalidae) are an understudied, group of marine anglerfishes that are dorsoventrally flattened and have an illicium and esca (terminal lure) used to attract prey. The family contains 10 genera and 75 recognized species from nearly all tropical and subtropical seas. Relationships among these taxa, as well as the position of Ogcocephalidae within Lophiiformes, remain poorly understood with previous studies showing conflicting, and poorly resolved results. The timing of divergence and depth of origination in the water column have also not been explored in any detail. In this study a concatenated nuclear (three genes) and mitochondrial …
Fall Armyworm (Lepidoptera: Noctuidae) Ecology In Southeastern Cotton, Jarrod T. Hardke, Gus M. Lorenz, B. Rogers Leonard
Fall Armyworm (Lepidoptera: Noctuidae) Ecology In Southeastern Cotton, Jarrod T. Hardke, Gus M. Lorenz, B. Rogers Leonard
Faculty Publications
The fall armyworm, Spodoptera frugiperda (J. E. Smith), is a sporadic pest with a diverse host range. This insect occasionally causes damage to cotton across the United States from the Rocky Mountains to the East Coast. Fall armyworm has been problematic in cotton due to its overall tolerance to many insecticide use strategies and difficulty in finding and surveying field infestations with sampling protocols. A review of insect biology, description of life stages, behavior and host strain identification, injury to cotton, and potential management options for the southeastern United States are presented.
Encouraging Greater Student Inquiry Engagement In Science Through Motivational Support By Online Scientist-Mentors, Stephen C. Scogin, Carol L. Stuessy
Encouraging Greater Student Inquiry Engagement In Science Through Motivational Support By Online Scientist-Mentors, Stephen C. Scogin, Carol L. Stuessy
Faculty Publications
Next Generation Science Standards (NGSS) call for integrating knowledge and practice in learning experiences in K-12 science education. PlantingScience (PS), an ideal curriculum for use as an NGSS model, is a computer-mediated collaborative learning environment intertwining scientific inquiry, classroom instruction, and online mentoring from scientists. With implementation in hundreds of classrooms across the United States, science teachers have noted PS as successful in motivating their students to engage in classroom inquiry investigations. To investigate the role of the online scientist-mentors in motivating students in the PS learning environment, we used self-determination theory (SDT) to guide a multiple case study of …
Jal In The Past Decade: A Comprehensive Analysis Of Academic Library Research, Lili Luo, Margaret Mckinney
Jal In The Past Decade: A Comprehensive Analysis Of Academic Library Research, Lili Luo, Margaret Mckinney
Faculty Publications
A content analysis is conducted to examine the peer-reviewed articles published in the Journal of Academic Librarianship (JAL) from 2004 to 2013. Five key variables are studied: authorship, article type, topic, research methods/design, and research theories/models. About three-fourths of the articles were authored by at least one librarian, and over half of the articles were co-authored. More than two-thirds of the articles were primary research articles, and a total of 24 topics related to academic libraries were covered, among which information literacy was the most popular one. Survey and content analysis are the two most frequently used research methods in …
First Record Of A Spotted Fever Group Rickettsia Sp. And Theileria Annulata In Hyalomma Dromedarii (Acari: Ixodidae) Ticks In The United Arab Emirates, Mohammad Ali Al-Deeb, Sabir Bin Muzaffar, Yousif Ali Abu-Zeid, Mohamed Rizk Enan, Shahid Karim
First Record Of A Spotted Fever Group Rickettsia Sp. And Theileria Annulata In Hyalomma Dromedarii (Acari: Ixodidae) Ticks In The United Arab Emirates, Mohammad Ali Al-Deeb, Sabir Bin Muzaffar, Yousif Ali Abu-Zeid, Mohamed Rizk Enan, Shahid Karim
Faculty Publications
Rickettsiosis and theileriosis can cause mortalities in camel populations. This study was conducted to achieve 2 objectives: (1) to detect the presence of SFG Rickettsia sp. and Theileria sp. in Hyalomma dromedarii Koch, 1844 (Acari: Ixodidae) ticks and (2) to determine their prevalence in the tick population on the sampled camel farms in Al-Ain, United Arab Emirates (UAE). Camel ticks (H. dromedarii) were collected from a total of 625 one-humped camels (Camelus dromedarius) in 22 sampling locations in Al-Ain, UAE. Tick samples were analyzed by Polymerase Chain Reaction (PCR). An SFG Rickettsia sp., which was 99% …
On The Transport Modes Of Fine Sediment In The Wave Boundary Layer Due To Resuspension/Deposition: A Turbulence-Resolving Numerical Investigation, Zhen Cheng, Xiao Yu, Tian Jian Hsu, Celalettin E. Ozdemir, S. Balachandar
On The Transport Modes Of Fine Sediment In The Wave Boundary Layer Due To Resuspension/Deposition: A Turbulence-Resolving Numerical Investigation, Zhen Cheng, Xiao Yu, Tian Jian Hsu, Celalettin E. Ozdemir, S. Balachandar
Faculty Publications
Previous field observations revealed that the wave boundary layer is one of the main conduits delivering fine sediments from the nearshore to continental shelves. Recently, a series of turbulence-resolving simulations further demonstrated the existence of a range of flow regimes due to different degrees of sediment-induced density stratification controlled by the sediment availability. In this study, we investigate the scenario in which sediment availability is governed by the resuspension/deposition from/to the bed. Specifically, we focus on how the critical shear stress of erosion and the settling velocity can determine the modes of transport. Simulations reveal that at a given wave …
Dissolved Fe And Al In The Upper 1000 M Of The Eastern Indian Ocean: A High‐Resolution Transect Along 95°E From The Antarctic Margin To The Bay Of Bengal, Maxime Grand, Christopher Measures, Mariko Hatta, William Hiscock, William Landing, Peter Morton, Clifton Buck, Pamela Barrett, Joseph Resing
Dissolved Fe And Al In The Upper 1000 M Of The Eastern Indian Ocean: A High‐Resolution Transect Along 95°E From The Antarctic Margin To The Bay Of Bengal, Maxime Grand, Christopher Measures, Mariko Hatta, William Hiscock, William Landing, Peter Morton, Clifton Buck, Pamela Barrett, Joseph Resing
Faculty Publications
A high‐resolution section of dissolved iron (dFe) and aluminum (dAl) was obtained along ~95°E in the upper 1000 m of the eastern Indian Ocean from the Antarctic margin (66°S) to the Bay of Bengal (18°N) during the U.S. Climate Variability and Predictability (CLIVAR) CO2 Repeat Hydrography I08S and I09N sections (February–April 2007). In the Southern Ocean, low concentrations of dAl (<1 n M) reflect the negligible dust inputs impacting the water masses subducted in the circumpolar domain. The low dAl concentrations characterizing the Southern Ocean terminate near 45°S, probably because of the advection of subtropical water masses that received dust and sedimentary inputs in their formation region. Our subsurface dFe data near the southern Kerguelen Plateau were significantly higher than historical observations in other Indian sectors of the Southern Ocean. We surmise that the offshore advection of dFe‐rich waters along the western flank of the southern Kerguelen plateau and enhanced vertical mixing could contribute to this elevated subsurface dFe inventory. Elevated subsurface particulate and dFe levels downstream of the northern Kerguelen Plateau may reflect long‐range lateral transport from the plateau's sediments and/or remineralization inputs. At the northern edge of the south Indian subtropical gyre, the deposition of Australian dust, possibly combined with the advection of dAl‐enriched waters from the Indonesian Throughflow, creates a region of elevated dAl in the upper 400 m but without a corresponding enrichment in dFe. In the northern Indian Ocean, the South Equatorial Current constitutes a remarkable biogeochemical front separating the oxygen‐rich and dFe‐poor subtropical gyre waters from the dFe‐rich and oxygen‐depleted waters of the northern Indian Ocean. By tracing the accumulation of macronutrients and dFe along the advective pathway of Indian Central Water, we show that the central waters of the northern Indian Ocean receive excess dFe in addition to that produced by remineralization inputs. The resuspension of shelf sediments and release of pore waters probably contribute to the elevated dFe and dAl levels observed below the highly stratified upper layers of the Bay of Bengal.