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Addressing The Challenges Of Cognitive Decline In The Physician Workforce, Sharona Hoffman
Addressing The Challenges Of Cognitive Decline In The Physician Workforce, Sharona Hoffman
Faculty Publications
This book chapter examines the growing challenge of cognitive decline among aging physicians and analyzes various approaches to addressing it. In 2024, twenty percent of working physicians were sixty-five or older, and evidence suggests that 12-14% of older clinicians have cognitive deficits that may affect job performance. The chapter evaluates two primary approaches to cognitive assessment: employer-initiated programs and programs operated by state medical boards. Employer "late career practitioner policies" (LCPP) that require older physicians to undergo testing are becoming increasingly popular among health care organizations. But they are vulnerable to challenge under disability and age discrimination laws, as evidenced …
Methods For Tagging Whale Sharks: Insights Into Performance And Best Practices With A Focus On Clamp Attachments, Freya C. Womersley, Sofia Green, Alberto Garcia-Baciero, Ronan Conlon, Amy L. Jeffries, Matt J. Waller, Sara S. Ratão, Nuno Queiroz, Pedro Afonso, Gonzalo Araujo, Adam Barnett, Christine Barry, Michael L. Berumen, Farukhkha Bloch, Ginevra Boldrocchi, Camrin D. Braun, Ryan Caillouet, Constance Chapman, Jesse E.M. Cochran
Methods For Tagging Whale Sharks: Insights Into Performance And Best Practices With A Focus On Clamp Attachments, Freya C. Womersley, Sofia Green, Alberto Garcia-Baciero, Ronan Conlon, Amy L. Jeffries, Matt J. Waller, Sara S. Ratão, Nuno Queiroz, Pedro Afonso, Gonzalo Araujo, Adam Barnett, Christine Barry, Michael L. Berumen, Farukhkha Bloch, Ginevra Boldrocchi, Camrin D. Braun, Ryan Caillouet, Constance Chapman, Jesse E.M. Cochran
Faculty Publications
Background: Biologging and telemetry have transformed our understanding of marine megafauna movement ecology. Yet, methodological constraints continue to limit data quality and deployment duration. Devices recording whale shark (Rhincodon typus) behaviours and movements have been used for decades, but they remain challenging to deploy and vary in success. Recently, spring-loaded clamp-based systems have emerged as one of the most widely used approaches to attach electronic tags to the fins of this globally endangered species. Currently, however, no consensus guidelines exist as to how to optimise this approach, potentially leading to continued underperforming deployments limiting analysis potential. Here, we synthesise experiences …
Uneven Surfaces, Chipped Plates And Hiding Spaces: Pedagogical Practices In The Nordic Outdoor Model Of Education, Karen Walker
Uneven Surfaces, Chipped Plates And Hiding Spaces: Pedagogical Practices In The Nordic Outdoor Model Of Education, Karen Walker
Faculty Publications
This article shares insights from a professional study tour of Danish early childhood education programmes, examining how social pedagogical principles are embedded in outdoor learning environments. During June 2024, a group of early childhood teacher educators from the United States visited forest kindergartens, adventure playgrounds and natural playscapes in Denmark as participants in the Nordic Outdoor Model of Education study tour. Through guided visits and observations, we documented pedagogical practices that demonstrate the application of social pedagogy– particularly the integration of head, heart and hands in supporting children’s holistic development. This article connects observed practices to social pedagogical theory, highlighting …
Waste Streams From Next Generation Molten Salt Reactors: The Challenge Of Creating An Insoluble Ceramic For Chloride Salt Waste, Alevtina A. Maksimova, Jake W. Amoroso, Matthew Page, Gregory Morrison, Hans Conrad Zur Loye
Waste Streams From Next Generation Molten Salt Reactors: The Challenge Of Creating An Insoluble Ceramic For Chloride Salt Waste, Alevtina A. Maksimova, Jake W. Amoroso, Matthew Page, Gregory Morrison, Hans Conrad Zur Loye
Faculty Publications
Molten salt reactors (MSRs) design development is of interest to many research groups and companies. Waste management for MSRs is one of the most important issues that needs to be resolved due to its impact on environmental safety, primarily via the dissolution of radionuclides in water. Furthermore, the waste treatment strategy will have a significant influence on the operating cost of MSRs, which is why a reliable process for the immobilization, transportation, storage and disposal of MSR waste must be addressed. This work presents a new approach for the immobilization of chloride salts from molten salt reactors in stable oxyhalide …
Enhancing A Mid-Wave Infrared Fourier Transform Hyperspectral Imager For Explosions, James T. Stofel, Kody A. Wilson, Martin Larivière-Bastien, Anthony L. Franz, Michael L. Dexter
Enhancing A Mid-Wave Infrared Fourier Transform Hyperspectral Imager For Explosions, James T. Stofel, Kody A. Wilson, Martin Larivière-Bastien, Anthony L. Franz, Michael L. Dexter
Faculty Publications
Capturing reliable hyperspectral imager data at a meaningful frame rate for explosions and other fast-changing scenes is not possible in the mid-wave infrared region under traditional sensor operating configurations and processing techniques, which typically have frame rates on the order of 0.5–2.0 Hz. To combat these shortcomings, the scene acquisition parameters were tailored for explosions and a new method for processing optical signatures of fast transient scenes with Fourier-transform infrared hyperspectral imagers was developed. For this technique, the instrument was first configured to collect asymmetric interferograms while optimizing the number of measurement points on the short side of the interferogram. …
Terahertz Electromagnetic Effects And Chirality-Induced Spin Selectivity In Dna, F. Matthew Mihelic Md
Terahertz Electromagnetic Effects And Chirality-Induced Spin Selectivity In Dna, F. Matthew Mihelic Md
Faculty Publications
The effects of terahertz electromagnetic stimulation of the DNA molecule can be understood through modeling of the quantum logical mechanics of the DNA molecule. Coherent conduction of electron spin states along the aromatic nucleotide base pairs and chirality-induced spin selectivity are two characteristics of the DNA molecule that are involved in the precise separation of the double-stranded DNA molecule at a specific location. Such modeling can inform predictions of DNA strand separation and has significant implications for understanding DNA transcription bubble formation.
Crystal Structure Of New Polar Rare Earth Borates Na2.62Ln2.12(Bo3)3 (Ln = Pr, Nd, Sm) Containing Isolated Bo3 Groups, Alevtina A. Maksimova, Mark D. Smith, Hans Conrad Zur Loye
Crystal Structure Of New Polar Rare Earth Borates Na2.62Ln2.12(Bo3)3 (Ln = Pr, Nd, Sm) Containing Isolated Bo3 Groups, Alevtina A. Maksimova, Mark D. Smith, Hans Conrad Zur Loye
Faculty Publications
Three new rare earth borates, Na2.62Ln2.12(BO3)3 (Ln = Pr, Nd, Sm), were synthesized via a high-temperature solution reaction using a BaCO3–H3BO3–NaF flux and structurally characterized by single-crystal X-ray diffraction analysis. The compounds crystallize in the orthorhombic space group Amm2 with lattice parameters a = 5.0985(10) Å, b = 11.180(2) Å, c = 7.1483(14) Å, and a unit cell volume of 407.48(14) Å3 (Z = 2) for Na2.62Pr2.12(BO3)3, a = 5.0983(10) Å, b = 11.181(2) Å, c = 7.1491(14) Å, and a unit cell volume of 407.51(14) Å3 (Z = 2) for Na2.62Nd2.12(BO3)3, and a = 5.08630(10) Å, b …
Single Crystal Growth Of The Orthoborate Nabalu(Bo3)2 And Optical Investigation Of Eu3+ And Tb3+ Doped Nabalu(Bo3)2, Alevtina A. Maksimova, Mark D. Smith, Lakshani W. Masachchi, Hans Conrad Zur Loye
Single Crystal Growth Of The Orthoborate Nabalu(Bo3)2 And Optical Investigation Of Eu3+ And Tb3+ Doped Nabalu(Bo3)2, Alevtina A. Maksimova, Mark D. Smith, Lakshani W. Masachchi, Hans Conrad Zur Loye
Faculty Publications
Sodium barium lutetium borate NaBaLu(BO3)2 crystals were synthesized using a high-temperature solution method. The crystal structure of this layered orthoborate is described and corresponds to that of an extensive orthoborates family, NaBaR(BO3)2 (R = Sc, Y, Yb, Tb – Lu). NaBaLu(BO3)2 was doped by Eu3+ and Tb3+ to explore its performance as a host material and to investigate the luminescent properties of the Eu3+ and Tb3+ doped materials. The emission spectra of the NaBaLu(BO3)2:Ln (Ln = Eu, Tb) crystals are presented. The most …
Indigenous Community Research Opportunities, Sharon Hausam, Aaron M. Canter
Indigenous Community Research Opportunities, Sharon Hausam, Aaron M. Canter
Faculty Publications
This is a working paper produced as part of National Science Foundation project #2115169, “Transforming Rural-Urban Systems: Trajectories for Sustainability in the Intermountain West,” known as the “Intermountain West Transformation Network” (TN), led by the University of New Mexico with institutional partners at three additional universities in New Mexico, two in Arizona, and one each in Utah, Colorado, and Washington. The TN’s Indigenous and Tribal engagement was supported through a contract with Dr. Sharon Hausam, additional work by Aaron M. Canter, coordination with Dr. Lani Tsinnajinnie, and an Advisory Committee on Indigenous Information Needs primarily comprised of Indigenous representatives in …
Instructional Slides From Molten Salt Electrochemistry Symposium (Moses) 2026, Devin Rappleye, Carlos Mejia, Alex Peroff
Instructional Slides From Molten Salt Electrochemistry Symposium (Moses) 2026, Devin Rappleye, Carlos Mejia, Alex Peroff
Faculty Publications
This instructional slide set was developed for the 2026 Molten Salt Electrochemistry Symposium (MoSES) as an introduction and review of fundamental electrochemical concepts and methods used in molten salt systems. The material is intended for students, researchers, and practitioners seeking to better understand and interpret electrochemical measurements in high-temperature molten salts.
Topics include electrochemical thermodynamics, kinetics, mass transfer, electrode potentials, cyclic voltammetry, chronopotentiometry, chronoamperometry, square-wave voltammetry, electrochemical impedance spectroscopy (EIS), and common approaches for analyzing electrochemical data. Emphasis is placed on building physical intuition, understanding underlying assumptions, recognizing common experimental artifacts, and connecting electrochemical signals to real chemical and transport …
A Survey Of Open Educational Resources Appropriate For Constructing And Teaching An Upper-Level, Undergraduate Course In The History Of Music Prior To 1800 For Music Majors, Jamie Weaver
Faculty Publications
Many open education resources are available for the study of music history. Yet, the majority ofsources I discovered are intended for students who are not music majors or who are at thebeginning of their historical study. The purpose of my study of open educational resources is tolocate and evaluate resources that would facilitate the creation and instruction of the first-semester survey course of an undergraduate survey in music history for music majors, the focusof which is the study of music before 1800. What follows is a broad, preliminary survey ofsources that could be used, mixed, reworked, or adapted to fulfill …
The Hope College Department Of Biology: The First 50+ Years, Christopher C. Barney
The Hope College Department Of Biology: The First 50+ Years, Christopher C. Barney
Faculty Publications
The Hope College Department of Biology was founded in 1899 with the appointment of the first Professor of Biology at Hope, Samuel Mast. During the first 50+ years of the Biology Department, there were eight total faculty members in the department, including Frances Koeman, the first female faculty member in the natural sciences. Four faculty members, Mast, Frank Patterson, Oscar Thompson, and Teunis Vergeer were primarily responsible for developing the department’s curriculum and programs, with Mast and Vergeer also carrying out published research. The department was housed primarily in Van Raalte Hall and the Science Building (now Lubbers Hall) for …
Upper Mora River Corridor Plan. Path To Social And Economic Recovery. A Working Paper, José A. Rivera Ph.D
Upper Mora River Corridor Plan. Path To Social And Economic Recovery. A Working Paper, José A. Rivera Ph.D
Faculty Publications
The Working Paper outlines a plan for the Upper Mora River Corridor as a path to the social and economic recovery of the watershed and its communities in the Mora Valley of New Mexico in the aftermath of the year 2022 wildfires. The first section of the plan includes an historical overview of the traditional gristmills of northern New Mexico and places where a few of them are preserved and still standing. The next section goes into detail as to the early commercial mills situated along the upper Mora River Corridor with a focus on the four remaining mills: the …
Description Of Leptuca Capillosa Sp. Nov., A New Fiddler Crab Species (Crustacea, Decapoda, Ocypodidae) From The Continental Coast Of Ecuador, Carl Thurman, Mariana Capparelli
Description Of Leptuca Capillosa Sp. Nov., A New Fiddler Crab Species (Crustacea, Decapoda, Ocypodidae) From The Continental Coast Of Ecuador, Carl Thurman, Mariana Capparelli
Faculty Publications
A new species of fiddler crab, Leptuca capillosa sp. nov., is described based on two preserved specimens from the U.S. National Museum of Natural History (Smithsonian) as the holotype and paratype. In addition, specimens (N = 46) collected at eight locations along the Pacific cost of Ecuador were used for an anatomical description and a biometric study. Biometric relationships among major anatomical features are described by linear-regression algorithms with coefficients of correlation and determination. From a previously published DNA analysis of the new species, L. capillosa sp. nov. is related to other Leptuca species in the Gelasiminae subfamily of …
Navigating The Cocoon: An Interpretative Phenomenological Analysis Of Mothers’ Experiences Of Seeking Diagnosis And Services For Children With Disabilities In Insular Rural American Samoa, Elizabeth Cutrer, Ocean K. Akau, Lorena Seu, Isabel Medina Hull, G. E. Kawika Allen, Ofa H. Kanuch, Cameron W. H. Hee, Melia Fonoimoana Garrett
Navigating The Cocoon: An Interpretative Phenomenological Analysis Of Mothers’ Experiences Of Seeking Diagnosis And Services For Children With Disabilities In Insular Rural American Samoa, Elizabeth Cutrer, Ocean K. Akau, Lorena Seu, Isabel Medina Hull, G. E. Kawika Allen, Ofa H. Kanuch, Cameron W. H. Hee, Melia Fonoimoana Garrett
Faculty Publications
This study examines how mothers raising children with disabilities in American Samoa experience the processes of seeking diagnosis, navigating special education, and advocating for services within an insular rural context. American Samoa, an unincorporated U.S. territory located 2600 miles from Hawaiʻi with a population under 50,000, represents a case of what we term insular rurality—a condition in which the structural disadvantages of rurality are intensified by oceanic isolation, territorial governance, and colonial history. Data were collected through three focus groups with fifteen mothers whose children hold a range of disability diagnoses, with a card sort activity at the outset of …
Institutional Influences And The Governance And Administration Of The Programa Produtor De Água Payment For Ecosystem Services Program In Brazil, Thomas G. Safford
Institutional Influences And The Governance And Administration Of The Programa Produtor De Água Payment For Ecosystem Services Program In Brazil, Thomas G. Safford
Faculty Publications
Payment-for-Ecosystem-Services (PES) has been promoted as an innovative approach to environmental governance capable of simultaneously advancing conservation and sustainable development objectives. While studies commonly assess the ecological and economic performance of PES schemes, less attention has been given to their organizational and administrative effectiveness. This study examines these governance dimensions of one of Latin America’s most prominent PES initiatives—the Water Producer Program (WPP) in Brazil. Drawing on a meta-synthesis of 125 publications, the analysis investigates how regulative, normative, and cultural-cognitive institutional forces shaped WPP implementation. Guided by neo-institutional theory and institutional bricolage, findings show that WPP governance operated through hybrid …
Main-Chain Ion-Pair Polybenzimidazole Membranes Enabling Reduced-Temperature Ht-Pemfc Operation (Down To 120°C), Brian C. Benicewicz, Huina Lin
Main-Chain Ion-Pair Polybenzimidazole Membranes Enabling Reduced-Temperature Ht-Pemfc Operation (Down To 120°C), Brian C. Benicewicz, Huina Lin
Faculty Publications
Proton exchange membrane (PEM) fuel cells are promising for clean and efficient energy conversion across diverse applications. High-temperature PEM fuel cells (HT-PEMFCs) using phosphoric acid (PA)-doped polybenzimidazole (PBI) can operate up to 200°C, but at lower temperatures, water-induced PA loss often leads to performance degradation and reduced durability. In this work, we present a new class of main-chain ion-pair PBI membranes by integrating the imidazolium-biphosphate ion-pair units directly into the PBI backbone. This design results in membranes with high acid content, stronger acid-polymer interactions and stabilized acid retention. In single-cell tests, the Im+-PBI15-3 wt.% exhibits peak power densities of 0.79 …
Don't Self-Opt Out Of Career Opportunities: Proceed With Confidence, Valerie Mendoza
Don't Self-Opt Out Of Career Opportunities: Proceed With Confidence, Valerie Mendoza
Faculty Publications
While reflecting on your career in the past, have you ever stepped back from an opportunity that you wanted because you doubted yourself? In the workplace, confidence often gets mistaken for competence, and that means talented employees can be overlooked simply because they hesitate. The truth is that confidence isn’t something you’re born with. It’s a skill you can build. This session will get you started on building that skill.
We’ll explore practical strategies to strengthen your confidence starting today. We’ll also break down the key differences between how confident individuals act compared to those who aren’t, so you can …
White Matter Microstructure Of Sensorimotor Projection Fibers In Chronic Low Back Pain, John R. White, Jennifer M.C. Vendemia, Zachary Baty, Sheri Silfies, Stephen A. Coombes
White Matter Microstructure Of Sensorimotor Projection Fibers In Chronic Low Back Pain, John R. White, Jennifer M.C. Vendemia, Zachary Baty, Sheri Silfies, Stephen A. Coombes
Faculty Publications
Introduction:
Chronic low back pain (cLBP) is linked to altered cortical sensorimotor structure and function, yet white matter microstructure in sensorimotor projection fibers remains poorly characterized. Objective: To address this gap, we used diffusion MRI to comprehensively characterize sensorimotor projection fibers in 44 patients with cLBP and 41 matched healthy controls.
Methods:
We estimated an array of microstructural measures, including fractional anisotropy (FA), extracellular free water fraction (FW), free water–corrected FA (fwcFA), and neurite orientation dispersion and density imaging (NODDI) metrics.
Results:
General linear models identified significantly higher FA and fwcFA and lower orientation dispersion index (ODI) in cLBP vs …
Mapping The Tar Vrna Interaction With Hiv-1 Integrase, Jian Sun, Rahul Yadav, Tolga Catmakas, Luke Fisher, Nicholas C. Fitzkee, Jacques J. Kessl
Mapping The Tar Vrna Interaction With Hiv-1 Integrase, Jian Sun, Rahul Yadav, Tolga Catmakas, Luke Fisher, Nicholas C. Fitzkee, Jacques J. Kessl
Faculty Publications
A series of critical interactions within the viral core between viral RNA (vRNA) and HIV-1 Integrase (IN) has previously been reported. In these studies, contact points between vRNA and IN were identified using RNA-seq and MS-based protein foot-printing approaches. Several IN amino acids located in its C-terminal domain (CTD) were found to be essential for vRNA binding, and their alanine substitution severely impacted the correct morphogenesis of the mature viral core. Here, we have used the TAR element to extend these studies by performing a comprehensive mapping of the interaction by deploying RNA crosslinking and NMR methodologies. Together, these approaches …
One Assay To Rule Them All: Development Of A Global Environmental Dna Tool To Support Range-Wide Surveys Of An Imperiled Sawfish And Its Application In The Eastern Tropical Pacific, Juan C. Cubillos-M, Annmarie Fearing, Demian D. Chapman, Peter M. Kyne, P. Joana Dias, Cindy Gonzalez, Ryan N. Lehman, Yaliana Chichaco, Bryan L. Huerta-Beltrán, Kayla L. Mcculloch, Sarah M. Toepfer, John K. Carlson, Nicole M. Phillips
One Assay To Rule Them All: Development Of A Global Environmental Dna Tool To Support Range-Wide Surveys Of An Imperiled Sawfish And Its Application In The Eastern Tropical Pacific, Juan C. Cubillos-M, Annmarie Fearing, Demian D. Chapman, Peter M. Kyne, P. Joana Dias, Cindy Gonzalez, Ryan N. Lehman, Yaliana Chichaco, Bryan L. Huerta-Beltrán, Kayla L. Mcculloch, Sarah M. Toepfer, John K. Carlson, Nicole M. Phillips
Faculty Publications
Environmental DNA (eDNA) has emerged as a powerful tool to support the conservation of threatened species. The sawfishes are one of the most imperiled vertebrate groups, with all five species classified as Critically Endangered on the IUCN Red List of Threatened Species. Owing to their toothy rostra, sawfishes are easily entangled in a wide range of fishing gear, with mortalities in fisheries and loss of habitat driving global declines. The Largetooth Sawfish, Pristis pristis, historically had a circumtropical range, but has experienced severe declines in geographic range and abundance. Viable populations are thought to be confined to northern Australia, but …
Recent Advances In The Juvenile-To-Adult Phase Transition, Yifei Liao, Mingli Xu
Recent Advances In The Juvenile-To-Adult Phase Transition, Yifei Liao, Mingli Xu
Faculty Publications
The transition from the juvenile to adult vegetative phase in Arabidopsis thaliana is a fundamental developmental process that integrates morphological and physiological maturation. Despite extensive study, how vegetative phase change is regulated and how this phase transition is coordinated with plant physiology remain incompletely understood. This review synthesizes recent advances in the molecular regulation and physiological functions of vegetative phase change. We summarize how developmental traits—such as leaf shape, trichome distribution, and margin serration—are controlled through distinct downstream targets of the age-dependent miR156–SPL pathway. We further highlight emerging insights into how epigenetic factors dynamically modify chromatin states of key regulatory …
The Phoenix Flora: Plant Survival, Succession, And Putative Adaptation In The Post-Atomic Landscapes Of Hiroshima And Nagasaki, Gian Marco Ludovici, Paola Amelia Tassi, Alba Iannotti, Colomba Russo, Fausto D'Agostino, Matilde Neble Segade, Timothy Mousseau, Andrea Malizia
The Phoenix Flora: Plant Survival, Succession, And Putative Adaptation In The Post-Atomic Landscapes Of Hiroshima And Nagasaki, Gian Marco Ludovici, Paola Amelia Tassi, Alba Iannotti, Colomba Russo, Fausto D'Agostino, Matilde Neble Segade, Timothy Mousseau, Andrea Malizia
Faculty Publications
The atomic bombings of Hiroshima and Nagasaki in 1945 created a unique environment of acute, high-dose ionizing radiation, contrasting sharply with the chronic low-dose rate exposure in the Chernobyl and Fukushima Exclusion Zones. This stands in stark contrast to the chronic, low-dose rate contamination that defines the Chernobyl and Fukushima Exclusion Zones. While the long-term ecological effects of the latter are well-documented, a systematic synthesis of the floral response to the atomic bombings is lacking. This review integrates historical data with modern radio-ecological principles to analyze plant survival and succession. We document the remarkable recovery of vegetation, from the resprouting …
The Phoenix Flora: Plant Survival, Succession, And Putative Adaptation In The Post-Atomic Landscapes Of Hiroshima And Nagasaki, Gian Marco Ludo, Paola Amelia Tassi, Alba Iannotti, Colomba Russo, Fausto D'Agostino, Matilde Neble Segade, Timothy Mousseau, Andrea Malizia
The Phoenix Flora: Plant Survival, Succession, And Putative Adaptation In The Post-Atomic Landscapes Of Hiroshima And Nagasaki, Gian Marco Ludo, Paola Amelia Tassi, Alba Iannotti, Colomba Russo, Fausto D'Agostino, Matilde Neble Segade, Timothy Mousseau, Andrea Malizia
Faculty Publications
The atomic bombings of Hiroshima and Nagasaki in 1945 created a unique environment of acute, high-dose ionizing radiation, contrasting sharply with the chronic low-dose rate exposure in the Chernobyl and Fukushima Exclusion Zones. This stands in stark contrast to the chronic, low-dose rate contamination that defines the Chernobyl and Fukushima Exclusion Zones. While the long-term ecological effects of the latter are well-documented, a systematic synthesis of the floral response to the atomic bombings is lacking. This review integrates historical data with modern radio-ecological principles to analyze plant survival and succession. We document the remarkable recovery of vegetation, from the resprouting …
Backscattering By Particles Of Sizes <0.2 Μm In Seawater, Xiaodong Zhang, Yuanheng Xiong
Backscattering By Particles Of Sizes <0.2 Μm In Seawater, Xiaodong Zhang, Yuanheng Xiong
Faculty Publications
We measured the angular scattering functions at 517 nm in different size fractions, including bulk and very small particles (VSP for diameters <0.2 μm), in a variety of waters ranging from coasts to open oceans and from surface to depths as deep as 3,000 m. The measurements revealed a strong covariation in backscattering between VSP and bulk particle populations. The fractional contribution by VSP decreases from 60% in clear oceanic water where bulk particle backscattering coefficient bbp is on the order of 0.001 m−1 to <2% in turbid coastal water where bbp ∼0.1 m−1. An empirical model is developed (r2 = 0.89) to estimate bbp for VSP from the bulk bbp, which can now be routinely obtained from satellite observations.
Panda-Plus-Bench: A Clinical Benchmark For Evaluating The Robustness Of Ai Foundation Models In Prostate Cancer Diagnosis, Joshua L. Ebbert, Dennis Della Corte
Panda-Plus-Bench: A Clinical Benchmark For Evaluating The Robustness Of Ai Foundation Models In Prostate Cancer Diagnosis, Joshua L. Ebbert, Dennis Della Corte
Faculty Publications
Artificial intelligence foundation models are increasingly deployed for prostate cancer Gleason grading, where GP3/GP4 distinction directly impacts treatment decisions (active surveillance vs. intervention). However, these models may achieve high validation accuracy by learning specimen-specific artifacts rather than generalizable biological features, limiting real-world clinical utility. We introduce PANDA-PLUS-Bench, a curated benchmark dataset derived from expertly annotated prostate biopsies designed specifically to quantify this failure mode. The benchmark comprises nine carefully selected whole slide images from nine unique patients containing diverse Gleason patterns, with non-overlapping tissue patches extracted at both 512 × 512 and 224 × 224-pixel resolutions across eight augmentation conditions. …
Modeling Individual Self-Protective Behavior During Epidemics, Geonsik Yu, Michael J. Garee, Mario Ventresca, Yuehwern Yih
Modeling Individual Self-Protective Behavior During Epidemics, Geonsik Yu, Michael J. Garee, Mario Ventresca, Yuehwern Yih
Faculty Publications
Protecting public health from infectious diseases requires collective action, as individual behaviors—such as vaccination and mask-wearing—directly influence disease dynamics. During the COVID-19 pandemic, unexpected public responses often undermined the effectiveness of interventions, highlighting the need to understand collective behavioral patterns and motivations to design more effective mitigation strategies. This study presents an agent-based simulation model that captures how individuals adjust self-protective behaviors based on evolving opinions about disease risk and examines how these decisions interact with external factors, such as public health interventions, to shape collective outcomes. To improve the representativeness of the simulated population, multiple datasets were integrated to …
Ai Need Not Make One Slothful, Roy A. Kaelin Jr
Ai Need Not Make One Slothful, Roy A. Kaelin Jr
Faculty Publications
As National Louis University seeks to plan and advance its way amid the potential perils and pitfalls of so-named artificial intelligence, one finds that with reasonable workflows and guard rails, the use of AI proposes both potential promise and prospect, to assist and augment the natural intelligence that students and teachers bring to the classroom, encouraging them to pursue STEM-related activities with the preparation and deployment of focused and directed AI-bots. This paper presents examples and a case study of that directed and focused approach, the incremental lessons learned to date, and a proposed path to advance worthwhile AI …
Increasing Pride Skills For Child Engagement Using Cdi-Only Ipcit With Children With Autism Spectrum Disorder, Jordan T. Etherington, Zachary C. Labrot, Emily R. Defouw, Brad Dufrene, Brittany D. Garza, Amarah Sweaks, Briley Newcomb
Increasing Pride Skills For Child Engagement Using Cdi-Only Ipcit With Children With Autism Spectrum Disorder, Jordan T. Etherington, Zachary C. Labrot, Emily R. Defouw, Brad Dufrene, Brittany D. Garza, Amarah Sweaks, Briley Newcomb
Faculty Publications
Many children with autism spectrum disorder (ASD) display elevated levels of challenging behaviors and decreased social engagement. Parent Child Interaction Therapy (PCIT) may help children with ASD increase rates at which they engage and interact with their caregivers. Existing barriers to treatment completion, including high attrition and travel time and costs, may be ameliorated by delivering PCIT virtually (iPCIT) and setting attainable mastery criteria. This study utilized a multiple baseline design across three caregiver-child dyads with ASD to determine whether an iPCIT protocol affected caregivers’ use of positive engagement skills, children’s engagement, and children’s challenging behaviors. Results demonstrated increased and …
Sequence Determinants Of Rna G-Quadruplex Unfolding By Arg-Rich Regions, Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui-Ting Lee, Jun Zhang
Sequence Determinants Of Rna G-Quadruplex Unfolding By Arg-Rich Regions, Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui-Ting Lee, Jun Zhang
Faculty Publications
RNA sequences with the potential to form G-quadruplexes (rGQs) are widespread but largely unfolded in cells by unknown mechanisms. rGQ folding status is a critical regulator of RNA splicing and translation. We show that rGQs can be unfolded by SR proteins, SR-related proteins, and other Arg-rich proteins, including SRSF1, SRSF3, SRSF9, U1-70K, and U2AF1. The length and composition of Arg-rich regions are key determinants of this activity: Arg residues are the primary drivers, while acidic residues attenuate the unfolding activity. To unfold ARPC2 rGQ, at least 13 Arg residues are required. Our findings identify Arg-rich proteins as previously unrecognized, helicase-independent …