Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (1841)
- Law (1566)
- Medicine and Health Sciences (754)
- Psychology (744)
- Business (682)
-
- Education (665)
- Arts and Humanities (583)
- Public Health (371)
- Religion (254)
- Sociology (207)
- Other Social and Behavioral Sciences (203)
- Educational Psychology (197)
- Life Sciences (192)
- Business Administration, Management, and Operations (188)
- Public Health Education and Promotion (186)
- Management Information Systems (170)
- Library and Information Science (159)
- Linguistics (143)
- Physical Sciences and Mathematics (126)
- Constitutional Law (122)
- Communication (121)
- Accounting (117)
- Educational Technology (116)
- Criminal Law (112)
- Communication Sciences and Disorders (102)
- Counseling Psychology (100)
- Civil Rights and Discrimination (88)
- Engineering (88)
- Nursing (85)
- Kinesiology (84)
- Institution
-
- Brigham Young University (1870)
- University of South Carolina (978)
- Louisiana State University (537)
- William & Mary Law School (389)
- San Jose State University (359)
-
- Andrews University (284)
- The University of Southern Mississippi (251)
- University of Missouri School of Law (204)
- Santa Clara Law (182)
- University of North Carolina School of Law (159)
- University of Northern Iowa (155)
- Stephen F. Austin State University (149)
- Case Western Reserve University School of Law (137)
- St. John's University School of Law (131)
- University of New Hampshire (129)
- Rollins College (93)
- Marquette University Law School (83)
- Hope College (80)
- Florida International University College of Law (77)
- University of South Dakota (71)
- Luther Seminary (64)
- Villanova University Charles Widger School of Law (63)
- Air Force Institute of Technology (51)
- East Texas A&M University (49)
- University of Southern Maine (44)
- National Louis University (42)
- University of Maine School of Law (42)
- Linfield University (37)
- Denison University (34)
- Arkansas State University (9)
- Keyword
-
- Children (96)
- Religion (90)
- Mental health (89)
- Gender (78)
- COVID-19 (70)
-
- Depression (70)
- Education (70)
- Physical activity (63)
- Psychology (55)
- Law (53)
- Marriage (51)
- Parenting (47)
- Public Health (46)
- Humans (45)
- Stress (45)
- Women (44)
- Discrimination (43)
- Resilience (43)
- Family (41)
- Communication (40)
- Health (40)
- United States (38)
- Evidence (36)
- Higher education (36)
- Anxiety (35)
- Emerging adulthood (35)
- Spirituality (35)
- Adolescents (34)
- Constitutional Law (34)
- Assessment (32)
- Publication Year
- File Type
Articles 3271 - 3300 of 6808
Full-Text Articles in Entire DC Network
Comparing The Academic Word List With The Academic Vocabulary List: Analyses Of Frequency And Performance Of English Language Learners, K. James Hartshorn, Judson M. Hart
Comparing The Academic Word List With The Academic Vocabulary List: Analyses Of Frequency And Performance Of English Language Learners, K. James Hartshorn, Judson M. Hart
Faculty Publications
Although use of the Academic Word List (AWL) has been successful and extensive in English as a second language (ESL) materials development and pedagogy (Coxhead 2000, 2011), some scholars have raised concerns about possible flaws. In an effort to overcome limitations, Gardner and Davies (2014) have presented a "new Academic Vocabulary List" (AVL). While their description suggests a number of potential advantages of the AVL over the AWL, these lists have yet to undergo ecologically valid comparisons based on actual ESL learner performance. Thus, this study compares the AWL with the AVL in an effort to identify some of the …
Run, Jane, Run! Gendered Responses To Political Party Recruitment, Jessica Robinson Preece, Olga B. Stoddard, Rachel Fisher
Run, Jane, Run! Gendered Responses To Political Party Recruitment, Jessica Robinson Preece, Olga B. Stoddard, Rachel Fisher
Faculty Publications
Many researchers point to gender inequities in party recruitment practices to explain women’s underrepresentation on the ballot. However, there has been little systematic research about how men and women respond to recruitment, so we do not know whether gender-balanced recruitment would actually lead to genderbalanced outcomes. We conduct two studies to address this question. First, in cooperation with a county Republican Party, we identically recruited 5510 male and 5506 female highly active party members to attend a free candidate training seminar. Republican women were half as likely to respond to the invitation as men. Second, we conducted a survey experiment …
Listener Perceptions Of Simulated Fluent Speech In Nonfluent Aphasia, Tyson G. Harmon, Adam Jacks, Katarina L. Haley, Richard A. Faldowski
Listener Perceptions Of Simulated Fluent Speech In Nonfluent Aphasia, Tyson G. Harmon, Adam Jacks, Katarina L. Haley, Richard A. Faldowski
Faculty Publications
Background: People with aphasia (PWA) are frequently perceived less favorably by listeners than their peers. These perceptions include incorrect assumptions that can prevent successful social interactions. While communication partner training has been shown to improve social outcomes related to the listener (see e.g., Kagan, Black, Duchan, Simmons-Mackie, & Square, 2001), changing the verbal output of PWA may also yield more favorable listener perceptions about the speech, speaker, and their own affective response. We investigated the effects of artificially altered fluency (i.e., simulated fluency) on listeners’ subjective impressions.
Aims: The purpose of the study was to (1) confirm that listeners perceive …
Identification And Development Of Patron Personas For An Academic Library, Holt Zaugg, Scott Rackham
Identification And Development Of Patron Personas For An Academic Library, Holt Zaugg, Scott Rackham
Faculty Publications
Purpose. Ranganathan’s Laws of Library Science and continued refinements to his initial laws place identification of patron’s needs and connection of those needs to library services of primary importance in libraries (Ranganathan, 1931; Crawford & Gorman, 1995; Noruzi, 2004). Identifying and developing personas or user group descriptions helps to identify the unique nature of library patrons. Each persona helps librarians to identify or create services specific to the persona of library patrons. As each library persona is better understood, the library faculty and staff are able to prepare and plan for service delivery. Initially personas were developed for undergraduate …
Firm-Specific Human Capital Investments As A Signal Of General Value: Revisiting Assumptions About Human Capital And How It Is Managed, Shad S. Morris, Sharon A. Alvarez, Jay B. Barney, Janice C. Molloy
Firm-Specific Human Capital Investments As A Signal Of General Value: Revisiting Assumptions About Human Capital And How It Is Managed, Shad S. Morris, Sharon A. Alvarez, Jay B. Barney, Janice C. Molloy
Faculty Publications
Research Summary:
Prior scholarship has assumed that firm-specific and general human capital can be analyzed separately. This paper argues that, in some settings, this is not the case because prior firm-specific human capital investments can be a market signal of an individual’s willingness and ability to make such investments in the future. As such, the willingness and ability to make firm-specific investments is a type of general human capital that links firm-specific and general human capital in important ways. The paper develops theory about these investments, market signals, and value appropriation. Then the paper examines implications for human resource management …
The Benefit Of Friends: The Importance Of Sexual Restraint And Friendship In Marriage Formation, Jason S. Carroll
The Benefit Of Friends: The Importance Of Sexual Restraint And Friendship In Marriage Formation, Jason S. Carroll
Faculty Publications
For young adults today, the word "friend" has multiple and sometimes contradictory meanings. For example, the term "friend" can refer to one's "best friend (BFF)" or "boyfriend" or "girlfriend"–labels that typically convey an ongoing relationship of commitment and concern between two people. But at the time, someone can be "friends" with several hundred people on their Facebook page, many of whom he or she never associates with or barely knows. And even a stranger is considered "friendly" when he is nice or courteous, even though there is no ongoing form of friendship in that association. In our modern society the …
Reliability Generalization Of The Multigroup Ethnic Identity Measure- Revised (Meim-R), Timothy B. Smith, Hayley Marie Herrington, Erin Feinauer, Derek Griner
Reliability Generalization Of The Multigroup Ethnic Identity Measure- Revised (Meim-R), Timothy B. Smith, Hayley Marie Herrington, Erin Feinauer, Derek Griner
Faculty Publications
Individuals’ strength of ethnic identity has been linked with multiple positive indicators, including academic achievement and overall psychological well-being. The measure researchers use most often to assess ethnic identity, the Multigroup Ethnic Identity Measure (MEIM), underwent substantial revision in 2007. To inform scholars investigating ethnic identity, a reliability generalization analysis was performed on data from the revised version (MEIM–R) and compared with data from the original MEIM. Random-effects weighted models evaluated internal consistency coefficients (Cronbach’s alpha). Reliability coefficients for the MEIM–R averaged α = .88 across 37 samples, a statistically significant increase over the average of α = .84 for …
Evolving Into Studio, Andrew S. Gibbons Iii
Evolving Into Studio, Andrew S. Gibbons Iii
Faculty Publications
Instructional design is practiced in a real-world setting; it should be learned in a setting like the one where it is practiced. As the practices themselves change, it becomes more natural for this to happen. This study of one design instructor’s experience over nearly 50 years demonstrates a path of evolution out of teaching design in a standard classroom, in which practice is secondary to didactics, into a studio setting, where didactics tend to occur after the student has experienced a need.
The Application Of Layer Theory To Design: The Control Layer, Andrew S. Gibbons Iii, Matt Langton
The Application Of Layer Theory To Design: The Control Layer, Andrew S. Gibbons Iii, Matt Langton
Faculty Publications
Validation of an architectural theory of instructional design layering is accomplished for one of the proposed layers by verifying the theory’s claim that for every layer there exists a body of design theory from outside the field of instructional design that is capable of informing design within that layer.
The Biodiversity Paradigm Shift: Adapting The Endangered Species Act To Climate Change, Kalyani Robbins
The Biodiversity Paradigm Shift: Adapting The Endangered Species Act To Climate Change, Kalyani Robbins
Faculty Publications
The Endangered Species Act (ESA) was designed to protect species that had been rendered more vulnerable to extinction as a result of human activity. As such, its implementation has traditionally focused on keeping human beings away from such species and giving the species (and their ecosystems) space to heal on their own. Climate change is altering the landscape everywhere on the globe, rendering the hands-off approach no longer sufficient. Active interventions will become more necessary as we get further into the changing climate. Taking decisive action in response to climate change will also require a fundamental shift in our approach …
Flagrant Police Abuse: Why Black Lives (Also) Matter To The Fourth Amendment, Joelle A. Moreno
Flagrant Police Abuse: Why Black Lives (Also) Matter To The Fourth Amendment, Joelle A. Moreno
Faculty Publications
No abstract provided.
Reliability And Concurrent Validity Of An Alternative Method Of Lateral Lumbar Range Of Motion In Athletes, Mark D. Hecimovich, Jeffrey J. Herbert
Reliability And Concurrent Validity Of An Alternative Method Of Lateral Lumbar Range Of Motion In Athletes, Mark D. Hecimovich, Jeffrey J. Herbert
Faculty Publications
Background: Cricket bowling involves combined spinal movements of side bending and rotation and, consequently, injury to the low back is a common problem. Therefore the assessment of lumbar spine kinematics has become a routine component in preseason screening. This includes static measurement of lateral spinal flexion as asymmetrical range of motion may predispose an athlete to low back injury.
Objectives: This study examined intra-rater reliability and concurrent validity of the fingertip-to-floor distance test (FFD) when compared to a criterion range of motion measure.
Methods: Thirty-four junior-level cricket players aged 13‑16 years were recruited. Lumbar spine lateral flexion …
Comparing Methods For Assessing The English Grammatical Development Of Spanish-Speaking English Learners, Lisa A. Fitton Ph.D., Mary Claire Wofford, Kristina N. Bustamante, Natasha De Novi, Bibiana Nuñez, Carla L. Wood
Comparing Methods For Assessing The English Grammatical Development Of Spanish-Speaking English Learners, Lisa A. Fitton Ph.D., Mary Claire Wofford, Kristina N. Bustamante, Natasha De Novi, Bibiana Nuñez, Carla L. Wood
Faculty Publications
Identifying valid and informative approaches for assessing young English learners (ELs) is essential for school-based speech-language pathologists (SLPs). The present paper focuses on two distinct approaches for assessing English grammatical development, a key component and indicator of language development for ELs. The approaches addressed are standardized normreferenced assessment and grammatical feature coding from story retell narratives. The authors review the utility of these approaches for evaluating the English grammatical development of Spanish-speaking ELs. A research example is provided to illustrate how a small sample (n = 18) of ELs performed on each of these English-based tasks. Findings reveal that children …
Pipes, Pools And Filters: How Collaboration Networks Affect Innovative Performance, Harpeet Singh, David Kryscynski, Xinxin Li, Ram Gopal
Pipes, Pools And Filters: How Collaboration Networks Affect Innovative Performance, Harpeet Singh, David Kryscynski, Xinxin Li, Ram Gopal
Faculty Publications
Innovation requires inventors to have both "new knowledge" and the ability to combine and configure knowledge (i.e. "combinatory knowledge") and such knowledge may flow through networks. We argue that both combinatory knowledge and new knowledge are accessed through collaboration networks, but that inventors' abilities to access such knowledge depends on its location in the network. Combinatory knowledge transfers from direct contacts, but not easily from indirect contacts. In contrast, new knowledge transfers from both direct and indirect contacts, but is far more likely to be new and useful when it comes from indirect contacts. Exploring knowledge flows in 69,476 patents …
Adolescent Summer Camp Volunteers’Attitudes Toward Peers With Disabilities, Megan Fort, Neil Lundberg, Ramon Zabriskie, Dennis Eggett, Mary Anne Prater, Keith Barney
Adolescent Summer Camp Volunteers’Attitudes Toward Peers With Disabilities, Megan Fort, Neil Lundberg, Ramon Zabriskie, Dennis Eggett, Mary Anne Prater, Keith Barney
Faculty Publications
This study explored themalleability of adolescent attitudes toward their peers with disabilities after volunteering in a summer day-camp. The Contact with Disabled Persons Scale (CDP) and the Multi-Dimensional Attitude Scale (MAS) were used to collect data in order to determine the association between volunteering in a recreation-based summer day camp and adolescent attitudes toward disability. After a covariateadjusted regression analysis, contact with individuals with disabilities was found to significantly predict change in attitudes toward disability. Dyadic interviews were held after camp participation to provide additional sources of data with potential for deeper understanding of the camp experience for volunteers. The …
Female Veterans’ Involvement In Outdoor Sports And Recreation, Neil Lundberg, Stacy Taniguchi, Rachel Mcgovern, Shauna Smith
Female Veterans’ Involvement In Outdoor Sports And Recreation, Neil Lundberg, Stacy Taniguchi, Rachel Mcgovern, Shauna Smith
Faculty Publications
Previous research has recognized the need to better understand the experience of female veterans and their adjustment upon returning home, especially considering that a growing number of veterans are women. Their stories, particularly as they relate to combat and the associated wounds of war, largely remain untold. Therefore, the purpose of this project was to employ a theoretical sample from Grounded Theory methodology to determine if similar recreation opportunity structure patterns existed in the use of outdoor sports and recreation for a sample of female veterans, as had been found in previous research with individuals with physical disabilities. The investigation …
Who Is Easier To Nudge?, John Beshears, James J. Choi, David Laibson, Brigitte C. Madrian, Sean (Xixiang) Wang
Who Is Easier To Nudge?, John Beshears, James J. Choi, David Laibson, Brigitte C. Madrian, Sean (Xixiang) Wang
Faculty Publications
Identifying who is more influenced by a default is challenging, since individuals may be more likely to remain at the default either because they are more susceptible to defaults in general or because the default is closer to their preferred choice. We apply a statistical model to ten large companies’ 401(k) plans to distinguish between these two channels. Even after controlling for contribution rate preferences, low-income and young individuals are slower to opt out of contribution rate defaults. The evidence is consistent with the default changing contribution rate preferences, as predicted by anchoring or endorsement effects, and there is weaker …
Your Memory Is Working Against You: How Eye Tracking And Memory Explain Habituation To Security Warnings, Bonnie Anderson, Jeffrey L. Jenkins, Anthony Vance, C. Brock Kirwan, David Eargle
Your Memory Is Working Against You: How Eye Tracking And Memory Explain Habituation To Security Warnings, Bonnie Anderson, Jeffrey L. Jenkins, Anthony Vance, C. Brock Kirwan, David Eargle
Faculty Publications
Securitywarnings are critical to the security of end users and their organizations, often representing the final defense against an attack. Because warnings require users to make a contextual judgment, it is critical that they pay close attention to warnings. However, research shows that users routinely disregard them. A major factor contributing to the ineffectiveness of warnings is habituation, the decreased response to a repeated warning. Although previous research has identified the problem of habituation, the phenomenon has only been observed indirectly through behavioral measures. Therefore, it is unclear how habituation develops in the brain in response to security warnings, and …
When Training Gets Trumped: How Dual-Task Interference Inhibits Security Training, Jeffrey L. Jenkins, Bonnie Anderson, Anthony Osborn Vance, Scott Jensen
When Training Gets Trumped: How Dual-Task Interference Inhibits Security Training, Jeffrey L. Jenkins, Bonnie Anderson, Anthony Osborn Vance, Scott Jensen
Faculty Publications
Security training programs are an important intervention to protect users and organizations against security threats. Unfortunately, users often ignore their training and engage in poor security behaviors. We explain how dual-task interference (DTI) is a primary cause of security training disregard. DTI is a cognitive limitation wherein humans cannot perform more than one task simultaneously without experiencing a deterioration of performance. In our context, we hypothesize how prompting users to perform security behaviors during high-DTI times may derail one’s previous security training, resulting in less secure behaviors.
We test our hypotheses in an experiment that compares users’ adherence to security …
Serious Games: An Evaluation Framework And Case Study, David W. Wilson, Jeff Jenkins, Nathan Twyman, Matthew Jensen, Joe Valacich, Norah Dunbar, Scott Wilson, Claude Miller, Bradley Adame, Yu-Hao Lee, Judee Burgoon, Jay F. Nunamaker
Serious Games: An Evaluation Framework And Case Study, David W. Wilson, Jeff Jenkins, Nathan Twyman, Matthew Jensen, Joe Valacich, Norah Dunbar, Scott Wilson, Claude Miller, Bradley Adame, Yu-Hao Lee, Judee Burgoon, Jay F. Nunamaker
Faculty Publications
Serious games show promise as an effective training method, but such games are complex and few guidelines exist for their effective evaluation. We draw on the design science literature to develop a serious game evaluation framework that emphasizes grounding evaluation in each of four key areas— theoretical, technical, empirical, and external. We further recommend that serious game developers assume an iterative, adaptive approach to grounding an evaluation effort in these four areas, emphasizing some areas more than others at different stages of the development cycle. We illustrate our framework using a case study of a large-scale serious game development project. …
Life Satisfaction Moderates The Associations Between Motives And Excessive Social Networking Site Usage, Jin-Liang Wang, James Gaskin, Hai-Zhen Wang, Dong Liu
Life Satisfaction Moderates The Associations Between Motives And Excessive Social Networking Site Usage, Jin-Liang Wang, James Gaskin, Hai-Zhen Wang, Dong Liu
Faculty Publications
It has been suggested that excessive social networking sites (SNS) users might use SNS as a method of coping with their life problems and that psychosocial well-being variables might interact with users’ motives for using SNS in predicting problematic SNS use. The present research explores whether the association between motives (i.e. self-expression and passing time) and excessive SNS usage is moderated by the user’s life satisfaction. A total of 996 college students were recruited from two colleges in Chongqing China. The participants were divided into excessive and nonexcessive SNS usage groups based on their mean score from the excessive SNS …
Real-Time Hand Tremor Detection Via Mouse Cursor Movements For Improved Human-Computer Interactions: An Exploratory Study, Parker A. Williams, Jeffrey L. Jenkins, Joseph S. Valacich
Real-Time Hand Tremor Detection Via Mouse Cursor Movements For Improved Human-Computer Interactions: An Exploratory Study, Parker A. Williams, Jeffrey L. Jenkins, Joseph S. Valacich
Faculty Publications
Millions of people experience hand-tremors—rhythmic oscillation of the fingers, hands, or arm that cause shaking in the hand. People who experience hand tremors often experience difficulty in human computer interactions. For example, when browsing a website, people with hand tremors may have difficulty navigating or clicking on links in the website. With sever hand tremors, effective computing is difficult without assistance. Past research has developed interventions that can be automatically deployed by a website to make it more accessible to people with hand tremors. We build on this research by creating a methodology to unobtrusively detect hand tremors, allowing these …
For Love Or Money? The Economic Consequences Of Delayed Marriage, Jason S. Carroll
For Love Or Money? The Economic Consequences Of Delayed Marriage, Jason S. Carroll
Faculty Publications
It has been well documented that over the last few decades we have seen a substantial increase in the median age of marriage in the United States. In fact, we are currently at all-time historic highs in these trends. According to the Current Population Survey from the U.S. Census, the median age of marriage right now is nearly 29 years of age for men and 27 years of age for women. Given the trajectory of this trend over the last several years, we are quickly approaching a time in our culture where half of marriages will occur for individuals after …
Restitution And The Excessive Fines Clause, Kevin Bennardo
Restitution And The Excessive Fines Clause, Kevin Bennardo
Faculty Publications
No abstract provided.
From Anthropophagy To Allegory And Back: A Study Of Classical Myth And The Brazilian Novel, Patrice Rankine
From Anthropophagy To Allegory And Back: A Study Of Classical Myth And The Brazilian Novel, Patrice Rankine
Faculty Publications
No abstract provided.
The Prominence Of Affect In Creativity: Expanding The Conception Of Creativity In Mathematical Problem Solving, Eric L. Mann, Scott A. Chamberlin, Amy K. Graefe
The Prominence Of Affect In Creativity: Expanding The Conception Of Creativity In Mathematical Problem Solving, Eric L. Mann, Scott A. Chamberlin, Amy K. Graefe
Faculty Publications
Constructs such as fluency, flexibility, originality, and elaboration have been accepted as integral components of creativity. In this chapter, the authors discuss affect (Leder GC, Pehkonen E, Törner G (eds), Beliefs: a hidden variable in mathematics education? Kluwer Academic Publishers, Dordrecht, 2002; McLeod DB, J Res Math Educ 25:637–647, 1994; McLeod DB, Adams VM, Affect and mathematical problem solving: a new perspective. Springer, New York, 1989) as it relates to the production of creative outcomes in mathematical problem solving episodes. The saliency of affect in creativity cannot be underestimated, as problem solvers require an appropriate state of mind in order …
Engineering Design And Gifted Pedagogy, Eric L. Mann, Rebecca L. Mann
Engineering Design And Gifted Pedagogy, Eric L. Mann, Rebecca L. Mann
Faculty Publications
No abstract provided.
Assessing And Achieving Jury Pool Representativeness, William Caprathe, Paula Hannaford-Agor, Stephanie Mccoy Loquvam, Shari Seidman Diamond
Assessing And Achieving Jury Pool Representativeness, William Caprathe, Paula Hannaford-Agor, Stephanie Mccoy Loquvam, Shari Seidman Diamond
Faculty Publications
Lack of representativeness is evident in the courtroom, but solutions must be pursued much earlier. The Jury Management Committee of the ABA’s National Conference of State Trial Judges, with Paula Hannaford-Agor of the National Center for State Courts (NCSC), identified a series of steps judges and administrators can take to determine if the procedures used to assemble jurors result in representative jury panels and improve the representativeness of jury panels. The steps focus on (1) establishing reliable methods of measuring the demographic composition of the jury pool, (2) ensuring the inclusiveness and representativeness of the jury pool, and (3) assessing …
'"Ideology" Or "Situation Sense"? An Experimental Investigation Of Motivated Reasoning And Professional Judgment, Dan M. Kahan, David Hoffman, Danieli Evans, Neal Devins, Eugene Lucci, Katherine Cheng
'"Ideology" Or "Situation Sense"? An Experimental Investigation Of Motivated Reasoning And Professional Judgment, Dan M. Kahan, David Hoffman, Danieli Evans, Neal Devins, Eugene Lucci, Katherine Cheng
Faculty Publications
This Article reports the results of a study on whether political predispositions influence judicial decisionmaking. The study was designed to overcome the two principal limitations on existing empirical studies that purport to find such an influence: the use of nonexperimental methods to assess the decisions of actual judges; and the failure to use actual judges in ideologically-biased-reasoning experiments. The study involved a sample of sitting judges (n = 253), who, like members of a general public sample (n = 800), were culturally polarized on climate change, marijuana legalization and other contested issues. When the study subjects were assigned to analyze …
Clinically Relevant Behavioral Endpoints In A Recurrent Nitroglycerin Migraine Model In Rats, Kenneth J. Sufka, Stephanie M. Staszko, Ainslee P. Johnson, Morgan E. Davis, Rachel E. Davis, Todd A. Smitherman
Clinically Relevant Behavioral Endpoints In A Recurrent Nitroglycerin Migraine Model In Rats, Kenneth J. Sufka, Stephanie M. Staszko, Ainslee P. Johnson, Morgan E. Davis, Rachel E. Davis, Todd A. Smitherman
Faculty Publications
BACKGROUND: This research sought to further validate the rat nitroglycerin (NTG) migraine model by comparing the effects of single versus recurrent NTG episodes on behavioral endpoints that mirror ICHD-3 diagnostic criteria for migraine, and to determine if the altered behavioral endpoints are reduced after administration of sumatriptan. METHODS: Separate cohorts of rats were administered NTG (10 mg/kg/2 ml) or saline (Experiment 1: single injection; Experiment 2: repeated injections; Experiment 3: repeated injections with sumatriptan [0.0, 0.3 and 1.0 mg/kg/ml] rescue. Behavioral endpoints were assessed 2 h after final NTG administration and included time in light/dark chambers for photophobia and activity, …