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Trademark Law And Consumer Constraints, Laura A. Heymann Jan 2022

Trademark Law And Consumer Constraints, Laura A. Heymann

Faculty Publications

Trademark law’s focus is on the consumer. Both the trademark literature and the marketing literature, however, tend to assume a consumer with few constraints on economic or cognitive processing resources. For example, scholars have argued that some confusion in the marketplace is not only inevitable but is also an overall positive in that encountering confusion trains consumers to be more resourceful and to learn how to interpret marketing communications more carefully. But not all consumers have the same level of cognitive and economic resources. Disadvantaged consumers—such as those not literate in the English language, those with lower socioeconomic status, and …


Automated Legal Guidance At Federal Agencies, Joshua D. Blank, Leigh Z. Osofsky Jan 2022

Automated Legal Guidance At Federal Agencies, Joshua D. Blank, Leigh Z. Osofsky

Faculty Publications

When individuals have questions about Federal benefits, services, and legal rules, they are increasingly seeking help from government chatbots, virtual assistants, and other automated tools. Current forms of automated legal guidance platforms include the U.S. Citizenship and Immigration Services’s “Emma,” the U.S. Department of Education’s “Aidan,” and the Internal Revenue Service’s “Interactive Tax Assistant.” Most scholars who have studied artificial intelligence and Federal government agencies have not focused on the government’s use of technology to offer guidance to the public. The absence of scholarly attention to automation as a means of communicating government guidance is an important gap in the …


A Faith For Today: Saving The Planet, Oystein S. Labianca Jan 2022

A Faith For Today: Saving The Planet, Oystein S. Labianca

Faculty Publications

No abstract provided.


Family Composition And Stability For Orphans: A Longitudinal Study Of Well-Being In 5 Low- And Middle-Income Countries, Christine L. Gray, Kathryn Whetten, Julie L. Daniels, Michael G. Hudgens, Audrey E. Pettifor, Amy M. Hobbie, Nathan M. Thielman, Misganaw E. Dubie, Dafrosa Itemba, Ira Madan, Vanroth Vann, Austine I. Wasonga, Rachel Manongi, Jan Ostermann Ph.D., Rachel A. Whetten, Brian W. Pence Dec 2021

Family Composition And Stability For Orphans: A Longitudinal Study Of Well-Being In 5 Low- And Middle-Income Countries, Christine L. Gray, Kathryn Whetten, Julie L. Daniels, Michael G. Hudgens, Audrey E. Pettifor, Amy M. Hobbie, Nathan M. Thielman, Misganaw E. Dubie, Dafrosa Itemba, Ira Madan, Vanroth Vann, Austine I. Wasonga, Rachel Manongi, Jan Ostermann Ph.D., Rachel A. Whetten, Brian W. Pence

Faculty Publications

Objectives: Many orphaned children in low- and middle-income countries live with family. Yet, their household composition and its stability are not well-characterized, nor is impact of stability on longer-term outcomes.

Methods: We used the longitudinal, multi-country Positive Outcomes for Orphans cohort to describe adult family living with orphans. Stability was measured by changes in presence of six familial relations over time, and related to three outcomes: 1) incident abuse, 2) cognitive functioning, 3) emotional difficulties. Associations were estimated using generalized linear models fit with generalized estimating equations. For abuse, Poisson regression estimated risk ratios. For continuous scores of cognitive functioning …


Basis For Changes In The Disease Burden Estimates Related To Vitamin A And Zinc Deficiencies In The 2017 And 2019 Global Burden Of Disease Studies, Sonja Y. Hess, Alexander C. Mclain, Haley Lescinsky, Kenneth H. Brown, Ashkan Afshin, Reed Atkin, Saskia Jm Osendarp Dec 2021

Basis For Changes In The Disease Burden Estimates Related To Vitamin A And Zinc Deficiencies In The 2017 And 2019 Global Burden Of Disease Studies, Sonja Y. Hess, Alexander C. Mclain, Haley Lescinsky, Kenneth H. Brown, Ashkan Afshin, Reed Atkin, Saskia Jm Osendarp

Faculty Publications

Background:

The Global Burden of Disease (GBD) Study provides estimates of death and disability from eighty-seven risk factors, including some micronutrient deficiencies. Objectives:

To review methodological changes that led to large differences in the disease burden estimates for vitamin A and Zn deficiencies between the GBD 2017 and 2019 Studies. Methods:

GBD publications were reviewed; additional information was provided by GBD researchers. Results:

Vitamin A deficiency prevalence is based on plasma retinol concentration, whereas the estimate for Zn deficiency prevalence uses dietary adequacy as a proxy. The estimated global prevalence of vitamin A deficiency for children aged 1–4 years in …


Nutrient Intake And Dietary Inflammatory Potential In Current And Recovered Anorexia Nervosa, Olivia Patsalos, Bethan Dalton, Christia Kyprianou, Joseph Firth, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Ulrike Schmidt, Hubertus Himmerich Dec 2021

Nutrient Intake And Dietary Inflammatory Potential In Current And Recovered Anorexia Nervosa, Olivia Patsalos, Bethan Dalton, Christia Kyprianou, Joseph Firth, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Ulrike Schmidt, Hubertus Himmerich

Faculty Publications

Anorexia nervosa (AN) is characterised by disrupted and restrictive eating patterns. Recent investigations and meta-analyses have found altered concentrations of inflammatory markers in people with current AN. We aimed to assess nutrient intake in participants with current or recovered AN, as compared to healthy individuals, and explore group differences in dietary inflammatory potential as a possible explanation for the observed alterations in inflammatory markers. We recruited participants with current AN (n = 51), those recovered from AN (n = 23), and healthy controls (n = 49). We used the Food Frequency Questionnaire (FFQ), to calculate a Dietary …


Gut Microbiota Composition And Predicted Microbial Metabolic Pathways Of Obesity Prone And Obesity Resistant Outbred Sprague-Dawley Cd Rats May Account For Differences In Their Phenotype, Diana N. Obanda, Michael J. Keenan, Ryan Page, Anne M. Raggio, Christopher M. Taylor, Brian D. Marx, Rhett W. Stout, Justin Guice, Meng Luo, David A. Welsh, Diana Coulon, Claudia Husseneder Dec 2021

Gut Microbiota Composition And Predicted Microbial Metabolic Pathways Of Obesity Prone And Obesity Resistant Outbred Sprague-Dawley Cd Rats May Account For Differences In Their Phenotype, Diana N. Obanda, Michael J. Keenan, Ryan Page, Anne M. Raggio, Christopher M. Taylor, Brian D. Marx, Rhett W. Stout, Justin Guice, Meng Luo, David A. Welsh, Diana Coulon, Claudia Husseneder

Faculty Publications

Like humans, outbred Sprague-Dawley CD rats exhibit a polygenic pattern of inheritance of the obese phenotype and not all individuals exposed to a high calorie intake develop obesity. We hypothesized that differences in gut microbiota composition account for phenotype differences between obese prone (OP) and obese resistant (OR) rats. We studied the gut microbiota composition of OPand OR rats after a high fat (HF) diet and how they respond to fermentation of resistant starch (RS). In phase 1 of the study 28 OP and 28 OR rats were fed a HF diet. In order to determine causal role of microbiota …


Oxidative Stress Indices In Asd Children In Sub-Sahara Africa, Ishiaq Olayinka Omotosho, Adekunbi Olufunke Akinade, Ikeoluwa Abiola Lagunju, Momoh A. Yakubu Dec 2021

Oxidative Stress Indices In Asd Children In Sub-Sahara Africa, Ishiaq Olayinka Omotosho, Adekunbi Olufunke Akinade, Ikeoluwa Abiola Lagunju, Momoh A. Yakubu

Faculty Publications

Background: The pathogenesis of autism spectrum disorder (ASD) remains a medical challenge even in the developed world. Although genetics and epigenetic factors have been variously indicted as major causes of the disorder, development of oxidative stress especially in the formative years of children has equally gained prominence as an etiological basis of the disorder. Oxidative stress is characterized by the production of excessive amounts of free radicals, decreased levels of antioxidants with the attendant imbalance in oxidant/antioxidant ratio. This study was designed to determine the levels of essential metals [magnesium (Mg), zinc (Zn), and copper (Cu)] and toxic metal, lead …


Domoic Acid And Pseudo-Nitzschia Spp. Connected To Coastal Upwelling Along Coastal Inhambane Province, Mozambique: A New Area Of Concern, Holly Kelchner, Katie E. Reeve-Arnold, Kathryn M. Schreiner, Sibel Bargu, Kim G. Roques, Reagan M. Errera Dec 2021

Domoic Acid And Pseudo-Nitzschia Spp. Connected To Coastal Upwelling Along Coastal Inhambane Province, Mozambique: A New Area Of Concern, Holly Kelchner, Katie E. Reeve-Arnold, Kathryn M. Schreiner, Sibel Bargu, Kim G. Roques, Reagan M. Errera

Faculty Publications

Harmful algal blooms (HABs) are increasing globally in frequency, persistence, and geo-graphic extent, posing a threat to ecosystem and human health. To date, no occurrences of marine phycotoxins have been recorded in Mozambique, which may be due to absence of a monitoring program and general awareness of potential threats. This study is the first documentation of neurotoxin, domoic acid (DA), produced by the diatom Pseudo-nitzschia along the east coast of Africa. Coastal Inhambane Province is a biodiversity hotspot where year-round Rhincodon typus (whale shark) sightings are among the highest globally and support an emerging ecotourism industry. Links between primary productivity …


International Society Of Sports Nutrition Position Stand: Caffeine And Exercise Performance, Nanci S. Guest, Trisha A. Vandusseldorp, Michael T. Nelson, Jozo Grgic, Brad J. Schoenfeld, Nathaniel D.M. Jenkins, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Jose Antonio, Jeffrey R. Stout, Eric T. Trexler, Abbie E. Smith-Ryan, Erica R. Goldstein, Douglas S. Kalman, Bill I. Campbell Dec 2021

International Society Of Sports Nutrition Position Stand: Caffeine And Exercise Performance, Nanci S. Guest, Trisha A. Vandusseldorp, Michael T. Nelson, Jozo Grgic, Brad J. Schoenfeld, Nathaniel D.M. Jenkins, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Jose Antonio, Jeffrey R. Stout, Eric T. Trexler, Abbie E. Smith-Ryan, Erica R. Goldstein, Douglas S. Kalman, Bill I. Campbell

Faculty Publications

Following critical evaluation of the available literature to date, The International Society of Sports Nutrition (ISSN) position regarding caffeine intake is as follows:1.Supplementation with caffeine has been shown to acutely enhance various aspects of exercise performance in many but not all studies. Small to moderate benefits of caffeine use include, but are not limited to: muscular endurance, movement velocity and muscular strength, sprinting, jumping, and throwing performance, as well as a wide range of aerobic and anaerobic sport-specific actions.2.Aerobic endurance appears to be the form of exercise with the most consistent moderate-to-large benefits from caffeine use, although the magnitude of …


The Validity Of Using One Force Platform To Quantify Whole-Body Forces, Velocities, And Power During A Plyometric Push-Up, Zhanxin Sha, Boyi Dai Dec 2021

The Validity Of Using One Force Platform To Quantify Whole-Body Forces, Velocities, And Power During A Plyometric Push-Up, Zhanxin Sha, Boyi Dai

Faculty Publications

Background: Previous studies have typically measured velocity and power parameters during the push-up, either using one or two force platforms. The purpose of the study was to compare the force, velocity, and power parameters between the one-force-platform method and the two-force-platform method during plyometric push-ups.

Methods: Thirty-four physically active young adults participated in the study to perform the plyometric push-up. For the two-force-platform calculation method, the forces applied to the feet and hands were both measured. For the one-force-platform calculation method, the forces applied to the feet were assumed to be constant, while the forces applied to hands …


Ale Beer Containing Free And Immobilized Lactobacillus Brevis, A Potential Delivery System For Probiotics, Kriza Faye Calumba, Vondel Reyes, Franklin Bonilla, Elio Villasmil, Subramaniam Sathivel Dec 2021

Ale Beer Containing Free And Immobilized Lactobacillus Brevis, A Potential Delivery System For Probiotics, Kriza Faye Calumba, Vondel Reyes, Franklin Bonilla, Elio Villasmil, Subramaniam Sathivel

Faculty Publications

Abstract: Probiotics in ale beer may be attractive to health-conscious consumers. However, beer conditions may decrease probiotic viability. Powder produced from durian (Durio zibethinus) rind, a by-product that is currently unutilized, can be used for the immobilization of probiotics. MRS medium was incubated with Lactobacillus brevis and periodically sampled to obtain the growth curve. Ale beer with free L. brevis and cells immobilized in durian rind powder was produced and separately assessed during storage at 21 °C for 24 days. The physico-chemical parameters of both beers did not differ significantly. Durian rind powder conferred protection up to 12 days of …


Occasions, Purposes, And Contexts For Offering Snacks To Preschool-Aged Children: Schemas Of Caregivers With Low-Income Backgrounds, Christine E. Blake, Kirsten K. Davison, Rachel E. Blaine, Jennifer O. Fisher Dec 2021

Occasions, Purposes, And Contexts For Offering Snacks To Preschool-Aged Children: Schemas Of Caregivers With Low-Income Backgrounds, Christine E. Blake, Kirsten K. Davison, Rachel E. Blaine, Jennifer O. Fisher

Faculty Publications

Objective Snacking among preschool aged children is nearly universal and has been associated with overconsumed nutrients, particularly solid fats and added sugars (SoFAS). This research examined caregivers’ schemas, or cognitive frameworks, for offering snacks to preschool-aged children.

Methods A qualitative design utilizing card sort methods was employed. Participants were 59 Black, Hispanic, and White caregivers of children aged 3–5 years with low-income backgrounds. Caregivers sorted 63 cards with images of commonly consumed foods/beverages by preschool-aged children in three separate card sorts to characterize snacking occasions, purposes, and contexts. The mean SoFAS content (kcal/100 g) of foods/beverages was evaluated by snacking …


Actions In Global Nutrition Initiatives To Promote Sustainable Healthy Diets, Ligia I. Reyes, Shilpa V. Constantinides, Shiva Bhandari, Edward A. Frongillo Jr. Ph.D., Pepijn Schreinemachers, Sigrid Wertheim-Heck, Helen Walls, Michelle Holdsworth, Amos Laar, Tuan Nguyen, Christopher Turner, Kate Wallard, Christine E. Blake Ph.D., Rd Dec 2021

Actions In Global Nutrition Initiatives To Promote Sustainable Healthy Diets, Ligia I. Reyes, Shilpa V. Constantinides, Shiva Bhandari, Edward A. Frongillo Jr. Ph.D., Pepijn Schreinemachers, Sigrid Wertheim-Heck, Helen Walls, Michelle Holdsworth, Amos Laar, Tuan Nguyen, Christopher Turner, Kate Wallard, Christine E. Blake Ph.D., Rd

Faculty Publications

Multiple recent global nutrition initiatives have recommended actions to transform food systems to improve food environments and food choice. This study aimed to identify actions recommended by these initiatives and understand their similarities and differences. Twelve global nutrition initiatives were reviewed, collectively spanning 13 action themes and accompanying strategies. Action themes were analyzed according to primary focus on either food environments and their food system drivers or food choice. Representation of the 13 actions varied across initiatives. Some actions overlapped; others were infrequently represented. Strategies targeting food environments and their food system drivers were more frequently recommended than strategies targeting …


Integrity, Freedom, And Trust – A Comprehensive Understanding Of Corruption And Its Effect On Human Rights, Nelu Burcea, Lucile Sabas, Carlos Biaggi Dec 2021

Integrity, Freedom, And Trust – A Comprehensive Understanding Of Corruption And Its Effect On Human Rights, Nelu Burcea, Lucile Sabas, Carlos Biaggi

Faculty Publications

Book of Abstracts, UNEQUAL WORLD Conference Third Edition


Nutrient Content And Stoichiometry Of Pelagic Sargassum Reflects Increasing Nitrogen Availability In The Atlantic Basin, B. E. Lapointe, R. A. Brewton, L. W. Herren, M. Wang, C. Hu, D. J. Mcgillicuddy, S. Lindell, F. J. Hernandez, P. L. Morton Dec 2021

Nutrient Content And Stoichiometry Of Pelagic Sargassum Reflects Increasing Nitrogen Availability In The Atlantic Basin, B. E. Lapointe, R. A. Brewton, L. W. Herren, M. Wang, C. Hu, D. J. Mcgillicuddy, S. Lindell, F. J. Hernandez, P. L. Morton

Faculty Publications

The pelagic brown macroalgae Sargassum spp. have grown for centuries in oligotrophic waters of the North Atlantic Ocean supported by natural nutrient sources, such as excretions from associated fishes and invertebrates, upwelling, and N2 fixation. Using a unique historical baseline, we show that since the 1980s the tissue %N of Sargassum spp. has increased by 35%, while %P has decreased by 44%, resulting in a 111% increase in the N:P ratio (13:1 to 28:1) and increased P limitation. The highest %N and δ15N values occurred in coastal waters influenced by N-rich terrestrial runoff, while lower C:N and …


The Church Bridge Project Focus Group Results: African American Perspectives Of Weight Management Programs To Improve Nutrition And Physical Activity Behaviors, Jennifer L. Lemacks, Laurie S. Abbott, Tammy Greer, Renee Gunn, Ashley Bryant, La Shaundrea Bradford, Penny A. Ralston Dec 2021

The Church Bridge Project Focus Group Results: African American Perspectives Of Weight Management Programs To Improve Nutrition And Physical Activity Behaviors, Jennifer L. Lemacks, Laurie S. Abbott, Tammy Greer, Renee Gunn, Ashley Bryant, La Shaundrea Bradford, Penny A. Ralston

Faculty Publications

Background: The prevalence of obesity is disproportionately high among African Americans in the Southern US. More information is needed about factors that influence participation in nutrition and physical activity programs to promote healthy weight.

Objective: The purpose of this study is to explore the weight management perceptions of young to middle aged adult African Americans.

Methods: The Church Bridge Project intervention participants were recruited for two focus groups. Qualitative data were recorded, transcribed and a thematic content analysis was conducted to identify major themes.

Results: Barriers included technology learning curve/burden and competing priorities. Facilitators included support, …


Challenges For Estimating The Global Prevalence Of Micronutrient Deficiencies And Related Disease Burden: A Case Study Of The Global Burden Of Disease Study, Sonja Y. Hess, Alexander C. Mclain Ph.D., Edward A. Frongillo Jr. Ph.D., Ashkan Afshin, Nicholas J. Kassebaum, Saskia Jm Osendarp, Reed Atkin, Rahul Rawat, Kenneth H. Brown Dec 2021

Challenges For Estimating The Global Prevalence Of Micronutrient Deficiencies And Related Disease Burden: A Case Study Of The Global Burden Of Disease Study, Sonja Y. Hess, Alexander C. Mclain Ph.D., Edward A. Frongillo Jr. Ph.D., Ashkan Afshin, Nicholas J. Kassebaum, Saskia Jm Osendarp, Reed Atkin, Rahul Rawat, Kenneth H. Brown

Faculty Publications

Information on the prevalence of micronutrient deficiencies is needed to determine related disease burden; underpin evidence-based advocacy; and design, deliver, and monitor safe, effective interventions. Assessing the global prevalence of deficiency requires a valid micronutrient status biomarker with an appropriate cutoff to define deficiency and relevant data from representative surveys across multiple locations and years. The Global Burden of Disease Study includes prevalence estimates for iodine, iron, zinc, and vitamin A deficiencies, for which recommended biomarkers and appropriate deficiency cutoffs exist. Because representative survey data are lacking, only retinol concentration is used to model vitamin A deficiency, and proxy indicators …


The Charitable Continuum, Eric Kades Dec 2021

The Charitable Continuum, Eric Kades

Faculty Publications

There are powerful fairness and efficiency arguments for making charitable donations to soup kitchens 100% deductible. These arguments have no purchase for donations to fund opulent church organs, yet these too are 100% deductible under the current tax code. This stark dichotomy is only the tip of the iceberg. Looking at a wider sampling of charitable gifts reveals a charitable continuum. Based on sliding scales for efficiency, multiple theories of fairness, pluralism, institutional competence and social welfare dictate that charitable deductions should in most cases be fractions between zero and one. Moreover, the Central Limit Theorem strongly suggests that combining …


A Healthy Dietary Pattern With A Low Inflammatory Potential Reduces The Risk Of Gestational Diabetes Mellitus, Lotta Pajunen, Liisa Korkalo, Noora Houttu, Outi Pellonperä, Kati Mokkala, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Tero Vahlberg, Kristina Tertti, Kirsi Laitinen Nov 2021

A Healthy Dietary Pattern With A Low Inflammatory Potential Reduces The Risk Of Gestational Diabetes Mellitus, Lotta Pajunen, Liisa Korkalo, Noora Houttu, Outi Pellonperä, Kati Mokkala, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Tero Vahlberg, Kristina Tertti, Kirsi Laitinen

Faculty Publications

Purpose An optimal diet for lowering the risk of gestational diabetes mellitus (GDM) is still to be defined, but may comprise of nutrient intakes, dietary patterns, diet quality, and eating frequency. This study was designed to investigate the contribution of diet in developing GDM in a comprehensive way. Methods The dietary intake of overweight or obese women, a risk group for GDM (n = 351), was assessed using 3-day food diaries and diet quality questionnaires in early pregnancy. Eating frequency and nutrient intakes were calculated, and dietary patterns identified using principal component analysis. The inflammatory potential of the diet was …


Examination Of Athlete Triad Symptoms Among Endurance-Trained Male Athletes: A Field Study, Erin M. Moore, Clemens Drenowatz, David F. Stodden, Kelly Pritchett, Thaddus C. Brodick, Brittany T. Williams, Justin M. Goins, Toni Torres-Mcgehee Phd, Lat, Atc Nov 2021

Examination Of Athlete Triad Symptoms Among Endurance-Trained Male Athletes: A Field Study, Erin M. Moore, Clemens Drenowatz, David F. Stodden, Kelly Pritchett, Thaddus C. Brodick, Brittany T. Williams, Justin M. Goins, Toni Torres-Mcgehee Phd, Lat, Atc

Faculty Publications

Background: Studies examining the physiological consequences associated with deficits in energy availability (EA) for male athletes are sparse.

Purpose: To examine male athlete triad components; low energy availability (LEA) with or without an eating disorder risk (ED), reproductive hormone [testosterone (T)], and bone mineral density (BMD) in endurance-trained male athletes during different training periods.

Methods: A cross-sectional design with 14 participants (age: 26.4 ± 4.2 years; weight: 70.6 ± 6.4 kg; height: 179.5 ± 4.3 cm; BMI: 21.9 ± 1.8 kg/m2) were recruited from the local community. Two separate training weeks [low (LV) and high (HV) training volumes] were used …


Social Determinants Of Health Related To Stay-At-Home Order Adherence And Social Distancing Attitudes Among A Diverse Deep South Population, Jennifer L. Lemacks, Tammy Greer, Sermin Aras, Laurie Abbott, Darlene Willis, June Gipson, Mohamed O. Elasri Nov 2021

Social Determinants Of Health Related To Stay-At-Home Order Adherence And Social Distancing Attitudes Among A Diverse Deep South Population, Jennifer L. Lemacks, Tammy Greer, Sermin Aras, Laurie Abbott, Darlene Willis, June Gipson, Mohamed O. Elasri

Faculty Publications

Objective: To describe COVID-19 related symptoms and medical care experienced in the first six months of the pandemic as well as stay-at-home order adherence, and attitudes related to COVID-19 risk and social distancing among a diverse sample of adults in the Deep South.

Methods: Survey data were collected from 411 Louisiana and Mississippi residents for three weeks in June 2020 through social media.

Results: Over half (52.5%) of participants who experienced COVID-19 related symptoms (with 41.5% experiencing at least one symptom) did not feel the severity of symptoms warranted seeking medical care. 91.6% of the Deep South …


The Dietary Inflammatory Index Is Not Associated With Gut Permeability Or Biomarkers Of Systemic Inflammation In Hiv Immunologic Non-Responders, Fat Malazogu, Rodney K. Rousseau, Nitin Shivappa Mbbs, Mph, Ph.D., Sanja Huibner, Sharon L. Walmsley, Colin M. Kovacs, Erika Benko, Robert J. Reinhard, Ron Rosenes, James R. Hébert, Rupert Kaul Nov 2021

The Dietary Inflammatory Index Is Not Associated With Gut Permeability Or Biomarkers Of Systemic Inflammation In Hiv Immunologic Non-Responders, Fat Malazogu, Rodney K. Rousseau, Nitin Shivappa Mbbs, Mph, Ph.D., Sanja Huibner, Sharon L. Walmsley, Colin M. Kovacs, Erika Benko, Robert J. Reinhard, Ron Rosenes, James R. Hébert, Rupert Kaul

Faculty Publications

Immunologic non-responders (INRs) are a subset of individuals living with HIV who have suboptimal blood CD4+ T cell recovery despite effective antiretroviral therapy (ART). They are at an increased risk of serious non-AIDS co-morbidities and death, and demonstrate enhanced systemic immune activation. In other populations diet has been correlated with markers of systemic inflammation through the Diet Inflammatory Index (DII), but this association has not been studied in persons living with HIV (PLWH). Blood was collected from 28 INR PLWH with a blood CD4+ T cell count <350/μL despite ≥2 years of effective ART. Participants completed a Canadian Diet History Questionnaire, and their responses were used to calculate the DII. Plasma inflammatory markers (IFNγ, TNF, IL-6, sVCAM, D-dimer, sCD14 and CRP) were assayed by ELISA, cellular immune activation (HLA-DR and CD38 on CD4+ and CD8+ T cells) was quantified using flow cytometry, and small bowel permeability assessed by calculation of the urine LacMan ratio after drinking a mix of lactulose and mannitol. Participants were a median age of 57 years, had been on effective ART for 15 years, and the median DII was −1.91 (range of −3.78 to +2.23). No correlation was observed between DII and plasma markers of inflammation, levels of T cell activation, gut permeability, or the biomarker of bacterial translocation sCD14. Self-reported alcohol intake, a potential confounder of the relationship between diet and inflammatory biomarkers, was also not associated with systemic inflammation or gut permeability. Our findings suggest that other mechanisms, rather than diet, are likely to be the major driver of systemic inflammation in INR individuals.


Challenges For Estimating The Global Prevalence Of Micronutrient Deficiencies And Related Disease Burden: A Case Study Of The Global Burden Of Disease Study, Sonja Y. Hess, Alexander C. Mclain, Edward A. Frongillo Jr., Ashkan Afshin, Nicholas J. Kassebaum, Saskia J. Osendarp, Reed Atkin, Rahul Rawat, Kenneth H. Brown Nov 2021

Challenges For Estimating The Global Prevalence Of Micronutrient Deficiencies And Related Disease Burden: A Case Study Of The Global Burden Of Disease Study, Sonja Y. Hess, Alexander C. Mclain, Edward A. Frongillo Jr., Ashkan Afshin, Nicholas J. Kassebaum, Saskia J. Osendarp, Reed Atkin, Rahul Rawat, Kenneth H. Brown

Faculty Publications

Information on the prevalence of micronutrient deficiencies is needed to determine related disease burden; underpin evidence-based advocacy; and design, deliver, and monitor safe, effective interventions. Assessing the global prevalence of deficiency requires a valid micronutrient status biomarker with an appropriate cutoff to define deficiency and relevant data from representative surveys across multiple locations and years. The Global Burden of Disease Study includes prevalence estimates for iodine, iron, zinc, and vitamin A deficiencies, for which recommended biomarkers and appropriate deficiency cutoffs exist. Because representative survey data are lacking, only retinol concentration is used to model vitamin A deficiency, and proxy indicators …


Apol1 Renal Risk Variants Are Associated With Obesity And Body Composition In African Ancestry Adults: An Observational Genotype-Phenotype Association Study, Girish N. Nadkarni, Kezhen Fei, Genevieve Galarneau, Yan Gao, James G. Wilson, Richard Cooper, Ebony B. Madden, Joshua C. Denny, Lynne D. Richardson, Martin Pollak, Ruth J.F. Loos, Carol R. Horowitz Nov 2021

Apol1 Renal Risk Variants Are Associated With Obesity And Body Composition In African Ancestry Adults: An Observational Genotype-Phenotype Association Study, Girish N. Nadkarni, Kezhen Fei, Genevieve Galarneau, Yan Gao, James G. Wilson, Richard Cooper, Ebony B. Madden, Joshua C. Denny, Lynne D. Richardson, Martin Pollak, Ruth J.F. Loos, Carol R. Horowitz

Faculty Publications

While increased obesity prevalence among persons of African ancestry (AAs) compared to persons of European ancestry (EAs) is linked to social, environmental and behavioral factors, there are no gene variants that are common and significantly associated with obesity in AA populations. We sought to explore the association between ancestry specific renal risk variants in the apolipoprotein L1 (APOL1) gene with obesity related traits in AAs. We conducted a genotype-phenotype association study from 3 electronic medical record linked cohorts (BioMe Biobank, BioVU, nuGENE); randomized controlled trials (genetic testing to understand and address renal disease disparities) and prospective cohort study (Jackson Heart …


Examining Eating Attitudes And Behaviors In Collegiate Athletes, The Association Between Orthorexia Nervosa And Eating Disorders, Nancy A. Uriegas, Zachary K. Winkelmann Phd, Lat, Atc, Kelly Pritchett, Toni Torres-Mcgehee Phd, Lat, Atc Nov 2021

Examining Eating Attitudes And Behaviors In Collegiate Athletes, The Association Between Orthorexia Nervosa And Eating Disorders, Nancy A. Uriegas, Zachary K. Winkelmann Phd, Lat, Atc, Kelly Pritchett, Toni Torres-Mcgehee Phd, Lat, Atc

Faculty Publications

Purpose: Orthorexia nervosa (Orthorexia) is an eating attitude and behavior associated with a fixation on healthy eating, while eating disorders (EDs) are clinically diagnosed psychiatric disorders associated with marked disturbances in eating that may cause impairment to psychosocial and physical health. The purpose of this study was to examine risk for Orthorexia and EDs in student-athletes across sex and sport type and determine the association between the two.

Methods: Student-athletes (n = 1,090; age: 19.6 ± 1.4 years; females = 756; males = 334) completed a survey including demographics, the ORTO-15 test (values), the Eating Attitudes Test-26 (EAT-26; >20 …


Steady Agronomic And Genetic Interventions Are Essential For Sustaining Productivity In Intensive Rice Cropping, Jagdish K. Ladha, Ando M. Radanielson, Jessica Elaine Rutkoski, Roland J. Buresh, Achim Dobermann, Olivyn Angeles, Irish Lorraine B. Pabuayon, Christian Santos-Medellin, Roberto Fritsche-Neto, Pauline Chivenge, Ajay Kohli Nov 2021

Steady Agronomic And Genetic Interventions Are Essential For Sustaining Productivity In Intensive Rice Cropping, Jagdish K. Ladha, Ando M. Radanielson, Jessica Elaine Rutkoski, Roland J. Buresh, Achim Dobermann, Olivyn Angeles, Irish Lorraine B. Pabuayon, Christian Santos-Medellin, Roberto Fritsche-Neto, Pauline Chivenge, Ajay Kohli

Faculty Publications

Intensive systems with two or three rice (Oryza sativa L.) crops per year account for about 50% of the harvested area for irrigated rice in Asia. Any reduction in productivity or sustainability of these systems has serious implications for global food security. Rice yield trends in the world's longest-running long-term continuous cropping experiment (LTCCE) were evaluated to investigate consequences of intensive cropping and to draw lessons for sustaining production in Asia. Annual production was sustained at a steady level over the 50-y period in the LTCCE through continuous adjustment of management practices and regular cultivar replacement. Within each of the …


Differences By School Location In Summer And School Monthly Weight Change: Findings From A Nationally Representative Sample, Ethan T. Hunt, Bridget Armstrong Ph.D., Gabrielle Turner-Mcgrievy Ph.D., Rd, Michael Beets Med, Mph, Phd, Robert Weaver Med, Phd Nov 2021

Differences By School Location In Summer And School Monthly Weight Change: Findings From A Nationally Representative Sample, Ethan T. Hunt, Bridget Armstrong Ph.D., Gabrielle Turner-Mcgrievy Ph.D., Rd, Michael Beets Med, Mph, Phd, Robert Weaver Med, Phd

Faculty Publications

Objectives: To examine changes in accelerations of Body Mass Index (BMI), age-and-sex specific body mass index (zBMI), and 95th percentile of BMI (%BMIp95) during the summer months and school year by school location designation (i.e., urban, suburban, exurban). This study utilized the Early Childhood Longitudinal Study Kindergarten Class of 2010-2011.

Methods: Of the 18,174 children in the ECLS-K:2011 dataset, I restricted participants to those with at least two consecutive measures that occurred August/September or April/May. Mixed-effect regression analyses estimated differences in monthly change in BMI, zBMI, and %BMIp95 between the summer and school year while accounting for the ECLS-K complex …


Impact Of Front-Of-Pack Labels On The Perceived Healthfulness Of A Sweetened Fruit Drink: A Randomised Experiment In Five Countries, Alejandra Jauregui, Christine M. White, Lana Vanderlee, Marissa G. Hall, Alejandra Contreras-Manzano, Claudia Nieto, Gary Sacks, Jim Thrasher Ph.D., Ma, Ms, David Hammond, Simón Barquera Nov 2021

Impact Of Front-Of-Pack Labels On The Perceived Healthfulness Of A Sweetened Fruit Drink: A Randomised Experiment In Five Countries, Alejandra Jauregui, Christine M. White, Lana Vanderlee, Marissa G. Hall, Alejandra Contreras-Manzano, Claudia Nieto, Gary Sacks, Jim Thrasher Ph.D., Ma, Ms, David Hammond, Simón Barquera

Faculty Publications

Objective: Front-of-pack (FOP) nutrition labelling is a globally recommended strategy to encourage healthier food choices. We evaluated the effect of FOP labels on the perceived healthfulness of a sweetened fruit drink in an international sample of adult consumers.

Design: Six-arm randomised controlled experiment to examine the impact of FOP labels (no label control, Guideline Daily Amounts (GDA), Multiple Traffic Lights, the Health Star Ratings (HSR), Health Warning Labels, and 'High-in' Warning Labels (HIWL)) on the perceived healthfulness of the drink. Linear regression models by country examined healthfulness perceptions on FOP nutrition labels, testing for interactions by demographic characteristics.

Setting: Online …


Cetacean Acousticwelfare In Wild And Managed-Care Settings: Gaps And Opportunities, Paige E. Stevens, Heather Hill, Jason N. Bruck Nov 2021

Cetacean Acousticwelfare In Wild And Managed-Care Settings: Gaps And Opportunities, Paige E. Stevens, Heather Hill, Jason N. Bruck

Faculty Publications

Cetaceans are potentially at risk of poor welfare due to the animals’ natural reliance on sound and the persistent nature of anthropogenic noise, especially in the wild. Industrial, commercial, and recreational human activity has expanded across the seas, resulting in a propagation of sound with varying frequency characteristics. In many countries, current regulations are based on the potential to induce hearing loss; however, a more nuanced approach is needed when shaping regulations, due to other non-hearing loss effects including activation of the stress response, acoustic masking, frequency shifts, alterations in behavior, and decreased foraging. Cetaceans in managedcare settings share the …