Digital Commons Network^™

Feasibility Of Re-Using Pete Soda Bottles To Exclude Oxygen During Storage Of Low Moisture Foods, Sarah Broderick, Michelle A. Lloyd, Lynn V. Ogden, Oscar A. Pike

Faculty Publications

Many consumers are beginning to store grain on their own creating a need for easy disinfestation methods that can be accomplished in the home. Oxygen deprivation has proven to be an effective method for grain disinfestation when kept below 1% for 12 days. Re-using PETE soda bottles is an easy way many consumers can store their grains. The purpose of this study was to determine if using oxygen absorber packets in used PETE soda bottles will keep the oxygen percent low enough to disinfest the grain stored in them. Experiments were carried out to determine how long oxygen absorber packets …

Evaluation Of The Late Life Disability Instrument In The Lifestyle Interventions And Independence For Elders Pilot (Life-P) Study, Fang-Chi Hsu, W. Jack Rejeski, Edward H. Ip, Jeff A. Katula, Roger A. Fielding, Alan M. Jette, Stephanie A. Studenski, Steven N. Blair, Michael E. Miller

Faculty Publications

Background: The late life disability instrument (LLDI) was developed to assess limitations in instrumental and management roles using a small and restricted sample. In this paper we examine the measurement properties of the LLDI using data from the Lifestyle Intervention and Independence for Elders Pilot (Life-P) study.

Methods: LIFE-P participants, aged 70-89 years, were at elevated risk of disability. The 424 participants were enrolled at the Cooper Institute, Stanford University, University of Pittsburgh, and Wake Forest University. Physical activity and successful aging health education interventions were compared after 12-months of follow-up. Using factor analysis, we determined whether the LLDI's factor …

Hras1 And Lass1 With Apoe Are Associated With Human Longevity And Healthy Aging, S. Michal Jazwinski, Sangkyu Kim, Jianliang Dai, Li Li, Xiuhua Bi, James C. Jiang, Jonathan Arnold, Mark A. Batzer, Jerilyn A. Walker, David A. Welsh, Christina M. Lefante, Julia Volaufova, Leann Myers, L. Joseph Su, Dorothy B. Hausman, Michael V. Miceli, Eric Ravussin, Leonard W. Poon, Katie E. Cherry, Michael A. Welsch

Faculty Publications

The search for longevity-determining genes in human has largely neglected the operation of genetic interactions. We have identified a novel combination of common variants of three genes that has a marked association with human lifespan and healthy aging. Subjects were recruited and stratified according to their genetically inferred ethnic affiliation to account for population structure. Haplotype analysis was performed in three candidate genes, and the haplotype combinations were tested for association with exceptional longevity. An HRAS1 haplotype enhanced the effect of an APOE haplotype on exceptional survival, and a LASS1 haplotype further augmented its magnitude. These results were replicated in …

Distribution Of Isoflavones And Antioxidant Activities Of Soybean Cotyledon, Coat And Germ, Xiaohua Yue, Ahmed Moursy Abdallah, Zhimin Xu

Faculty Publications

Soy isoflavones in the cotyledon, coat and germ of four soybean varieties from the southern U.S.A. were determined and compared. Isoflavones with aglycone, daidzein, genistein, glycitein and aglycone, withβ-glucoside, genistin, daidzin and glycitin, were found in the four varieties. The range of total soy isoflavones in cotyledon, coat and germ extracts from the varieties was 2.73-9.71, 5.56-16.94 and 27.76-81.43 mg/g, respectively. Soy germ was the richest source of isoflavones among the three soybean parts. Distribution of the isoflavones in soy cotyledon was different from that in soy coat or germ. Daidzin and glycitin were the major isoflavones in the germ …

Stable Isotope Analysis Reveals Detrital Resource Base Sources Of The Tree Hole Mosquito, Aedes Triseriatus, Michael G. Kaufman, Kirsten S. Pelz-Stelinski, Donald A. Yee, Steven A. Juliano, Peggy H. Ostrom, Edward D. Walker

Faculty Publications

1. Detritus that forms the basis for mosquito production in tree hole ecosystems can vary in type and timing of input. We investigated the contributions of plant‐ and animal‐derived detritus to the biomass of Aedes triseriatus (Say) pupae and adults by using stable isotope (¹⁵N and ¹³C) techniques in laboratory experiments and field collections.
2. Laboratory‐reared mosquito isotope values reflected their detrital resource base, providing a clear distinction between mosquitoes reared on plant or animal detritus.
3. Isotope values from field‐collected pupae were intermediate between what would be expected if a single (either plant or animal) detrital source dominated the …

Beneath The Salt Marsh Canopy: Loss Of Soil Strength With Increasing Nutrient Loads, R. Eugene Turner

Faculty Publications

Although the broadly observed increase in nutrient loading rates to coastal waters in the last 100 years may increase aboveground biomass, it also tends to increase soil metabolism and lower root and rhizome biomass—responses that can compromise soil strength. Fourteen different multiyear field combinations of nutrient amendments to salt marshes were made to determine the relationship between soil strength and various nitrogen, phosphorus, and nitrogen+phosphorus loadings. There was a proportional decline in soil strength that reached 35% in the 60- to 100-cm soil layer at the highest loadings and did not level off. These loading rates are equivalent to those …

Correlating Pharmaceutical Data With A National Health Survey As A Proxy For Estimating Rural Population Health, Ronald E. Cossman, Jeralynn S. Cossman, Wesley L. James, Troy Blanchard, Richard Thomas, Louis G. Pol, Arthur G. Cosby

Faculty Publications

Background: Chronic disease accounts for nearly three-quarters of US deaths, yet prevalence rates are not consistently reported at the state level and are not available at the sub-state level. This makes it difficult to assess trends in prevalence and impossible to measure sub-state differences. Such county-level differences could inform and direct the delivery of health services to those with the greatest need.Methods: We used a database of prescription drugs filled in the US as a proxy for nationwide, county-level prevalence of three top causes of death: heart disease, stroke, and diabetes. We tested whether prescription data are statistically valid proxy …

Glutamine Synthetase Partitioning In Native And Introduced Salt Marsh Grasses, Eric L.G. Hazelton, Thomas J. Knight Phd, Theresa A. Theodose Phd

Faculty Publications

Plants with higher glutamine synthetase (GS) activity in photosynthetic tissues than below-ground structures (high leaf:root [L:R] GS activity) show growth advantages over plants with a low L:R GS activity ratio. The benefits of a high L:R GS activity ratio are well documented in agricultural systems, but little is known about the ecology of GS partitioning in natural systems. To determine the ecological significance of GS partitioning, we measured above- and below-ground GS activity in Spartina grasses field-collected from a Maine salt marsh and others raised in a growth chamber from seed. The more stress-tolerant, faster growing S. alterniflora had a …

Estimates Of Heritability For Reproductive Traits In Captive Rhesus Macaque Females, Christine Gagliardi, Kathrine P. Falkenstein, Donald E. Franke, H. Michael Kubisch

Faculty Publications

Records from a colony of captive Indian rhesus macaques (Macaca mulatta) were used to estimate heritability for a number of reproductive traits. Records were based on a total of 7,816 births by 1,901 females from 1979 to 2007. Heritability was estimated with a linear animal model using a multiple trait derivative free REML set of programs. Because no male parents were identified, the numerator relationship matrix contained female kinships established over six generations. Reproductive traits included female age at the birth of the first, second and last infant, age at death, inter-birth intervals, number of infants born per female and …

Contribution Of Exogenous Dietary Carbohydrases To The Metabolizable Energy Value Of Corn Distillers Grains For Broiler Chickens, O. Adeola, J. A. Jendza, L. L. Southern, S. Powell, A. Owusu-Asiedu

Faculty Publications

The objectives of this study were to determine the ileal digestible energy (IDE), ME, and MEn contents of corn distillers grains (CDG) for broiler chickens and to quantify these energy utilization responses to carbohydrase supplementation by the regression method. The CDG sample used in the current experiment contained (by analysis) 936 g/kg of DM, 4,894 kcal/kg of gross energy, 315.1 g/kg of CP, 94.6 g/kg of crude fat, 94.8 g/kg of crude fiber, 495.6 g/kg of neutral detergent fiber, 179.1 g/kg of acid detergent fiber, 0.19 g/kg of Ca, and 4.8 g/kg of P. The studies were conducted at 2 …

Commute Times, Food Retail Gaps, And Body Mass Index In North Carolina Counties, Stephanie B. Jilcott, Haiyong Liu, Justin B. Moore, Jeffrey W. Bethel, James Wilson, Alice S. Ammerman

Faculty Publications

Introduction: The prevalence of obesity is higher in rural than in urban areas of the United States, for reasons that are not well understood. We examined correlations between percentage of rural residents, commute times, food retail gap per capita, and body mass index (BMI) among North Carolina residents.

Methods: We used 2000 census data to determine each county's percentage of rural residents and 1990 and 2000 census data to obtain mean county-level commute times. We obtained county-level food retail gap per capita, defined as the difference between county-level food demand and county-level food sales in 2008, from the North Carolina …

Postpartum Depression And Culture: Pesado Corazon, Lynn Clark Callister, Renea L. Beckstrand, Cheryl A. Corbett

Faculty Publications

The purpose of this article is to describe what the -literature has shown about postpartum depression (PPD) in culturally diverse women. The majority of qualitative studies done with women identified as -having PPD have been conducted with Western -women, with the second largest group focusing on Chinese women. This article reviews the qualitative studies in the literature and discusses how the management of PPD in technocentric and ethnokinship cultures differs. Social support has been shown to be significantly related to fewer symptoms of PPD, and culturally prescribed practices may or may not be -cultural mediators in decreasing the incidence of …

Neighborhood Effects On Health: Concentrated Advantage And Disadvantage, Brian K. Finch, D. Phuong Do, Melonie Heron, Chloe E. Bird, Teresa Seeman, Nicole Lurie

Faculty Publications

We investigate an alternative conceptualization of neighborhood context and its association with health. Using an index that measures a continuum of concentrated advantage and disadvantage, we examine whether the relationship between neighborhood conditions and health varies by socio-economic status. Using NHANES III data geo-coded to census tracts, we find that while largely uneducated neighborhoods are universally deleterious, individuals with more education benefit from living in highly educated neighborhoods to a greater degree than individuals with lower levels of education.

Reducing Portion Size Reduces Food Intake And Plate Waste, Marjorie Freedman, Carolina Brochado

Faculty Publications

As portion size (PS) increases, so does food intake. The effect of decreasing PS on food intake in a nonlaboratory setting is unknown. This 5-week study sought to determine whether decreasing PS resulted in decreased intake of the same food, and if so, at what point further PS reductions might lack benefit. It also assessed effects of PS reduction on food production and waste in a university all-you-can-eat dining facility (DF). Subjects were primarily freshmen who regularly ate lunch at the DF, and self-selected French fries (FF) presented in individual paper bags, portioned originally at 88 g, and decreased ∼15 …

A “Healthy Pizza Kitchen” Nutrition Education Program At A Children's Health Museum, Marjorie Freedman

Faculty Publications

For nutrition education to be successful in changing behavior, schools, families, and communities must participate in or provide a variety of diverse, creative, accessible, and culturally appropriate programs. One venue for provision of nutrition education is a health and science education center that has exhibits and special programs not found in an average school. Establishing relationships with these organizations could greatly enhance a school health curriculum.1 Although nutrition information, displays, and programming are often found in these centers, studies examining whether provision of nutrition education in these venues increases knowledge or changes behavior are lacking. The purpose of this study, …

Obesity Increases The Production Of Proinflammatory Mediators From Adipose Tissue T Cells And Compromises Tcr Repertoire Diversity: Implications For Systemic Inflammation And Insulin Resistance, Hyunwon Yang, Yun Hee Youm, Bolormaa Vandanmagsar, Anthony Ravussin, Jeffrey M. Gimble, Frank Greenway, Jacqueline M. Stephens, Randall L. Mynatt, Vishwa Deep Dixit

Faculty Publications

Emerging evidence suggests that increases in activated T cell populations in adipose tissue may contribute toward obesity-associated metabolic syndrome. The present study investigates three unanswered questions: 1) Do adipose-resident T cells (ARTs) from lean and obese mice have altered cytokine production in response to TCR ligation?; 2) Do the extralymphoid ARTs possess a unique TCR repertoire compared with lymphoid-resident T cells and whether obesity alters the TCR diversity in specific adipose depots?; and 3) Does short-term elimination of T cells in epididymal fat pad without disturbing the systemic T cell homeostasis regulate inflammation and insulin-action during obesity? We found that …

Body Image In Middle-Aged Mormon Women: A Comparative Case Study, Janette Olsen

Faculty Publications

Body image is a multifaceted construct developed from perceived experiences and personal and cultural attitudes towards the body. Women are more vulnerable than men to internal and external influences regarding negative body image. A qualitative comparative case study design was utilized to explore how 10 lifelong, middle-aged LDS women, either married (n=5) with children or single, never married (n=5), experienced body image through their perceptions of religiosity and spirituality. The participants lived along the Wasatch Front in Utah and were recruited through known LDS gatekeepers. Each participant completed three in-person interviews and three audio or paper journals, which were transcribed …

Alteration Of Microbial Communities Colonizing Leaf Litter In A Temperate Woodland Stream By Growth Of Trees Under Conditions Of Elevated Atmospheric Co2, John J. Kelly, Amit Bansal, Jonathan Winkelman, Lori R. Janus, Shannon Hell, Marie Wencel, Patricia Belt, Kevin A. Kuehn, Steven T. Rier, Nancy C. Tuchman

Faculty Publications

Elevated atmospheric CO₂ can cause increased carbon fixation and altered foliar chemical composition in a variety of plants, which has the potential to impact forested headwater streams because they are detritus-based ecosystems that rely on leaf litter as their primary source of organic carbon. Fungi and bacteria play key roles in the entry of terrestrial carbon into aquatic food webs, as they decompose leaf litter and serve as a source of nutrition for invertebrate consumers. This study tested the hypothesis that changes in leaf chemistry caused by elevated atmospheric CO₂ would result in changes in the size and …

Metabolic Syndrome And Risk Of Death From Cancers Of The Digestive System, Charles E. Matthews, Xuemei Sui, Michael J. Lamonte, Swann A. Adams, James R. Hébert, Steven N. Blair

Faculty Publications

We tested the hypothesis that risk of early mortality from cancers of the digestive system will be greater in men with, compared to men without, the metabolic syndrome (MetS). Participants were 33,230 men who were seen at the Cooper Clinic in Dallas, Texas and followed for 14.4 (SD=7.0) yrs. MetS was defined as having at least three of the following risk factors: abdominal obesity, fasting hypertriglyceridemia, low high-density lipoprotein cholesterol, high blood pressure, or high fasting glucose level or diabetes. MetS was associated with higher mortality (HR=1.90 [95% Confidence Interval=1.42-2.55]), and there was a graded positive association for the addition …

Co-Varying Patterns Of Physical Activity And Sedentary Behaviors And Their Long-Term Maintenance Among Adolescents, Jihong Liu, Jinseok Kim, Natalie Colabianchi, Andrew Ortaglia, Russell R. Pate

Faculty Publications

Background: We examined the covarying patterns of physical activity and sedentary behaviors among adolescents and their long-term maintenance. Methods: Data came from the National Longitudinal Study of Adolescent Health (1995-2002). We used latent class analysis to identify distinct covarying patterns in adolescence. Logistic regression models were used to predict odds of meeting moderate-to-vigorous physical activity (MVPA) recommendations (≥5 bouts/week) and exceeding screen time guidelines (>2 hours/day) 6 years later based on their adolescent class profile. Results: Five classes for each gender were identified and labeled as low physical activity (PA)/low sedentary behaviors (SED), moderate (Mod) PA/high (HI) SED, Mod …

Bending Nature, Bending Law, David Owen

Faculty Publications

No abstract provided.

Promoting Physical Activity In Afterschool Programs, Aaron Beighle, Michael W. Beets, Heather E. Erwin, Jennifer Huberty, Justin B. Moore, Megan Stellino

Faculty Publications

No abstract provided.

War Paths, Peace Paths: An Archaeology Of Cooperation And Conflict In Native Eastern North America, By David H. Dye, Charles R. Cobb

Faculty Publications

A review of War Paths, Peace Paths: an Archaeology of Cooperation and Conflict in Native Eastern North America, by David H. Dye.

Chemical Inhibition Of Caax Protease Activity Disrupts Yeast Ras Localization, Surya P. Mandahar, Emily R. Hildebrandt, William H. Jacobsen, George M. Santangelo, Walter K. Schmidt

Faculty Publications

Proteins possessing a C-terminal CaaX motif, such as the Ras GTPases, undergo extensive post-translational modification that includes attachment of an isoprenoid lipid, proteolytic processing and carboxylmethylation. Inhibition of the enzymes involved in these processes is considered a cancer-therapeutic strategy. We previously identified nine in vitro inhibitors of the yeast CaaX protease Rce1p in a chemical library screen (Manandhar et al., 2007). Here, we demonstrate that these agents disrupt the normal plasma membrane distribution of yeast GFP-Ras reporters in a manner that pharmacologically phenocopies effects observed upon genetic loss of CaaX protease function. Consistent with Rce1p being the in vivo target …

Comparison Of A Reduced Carbohydrate And Reduced Fat Diet For Ldl, Hdl, And Vldl Subclasses During 9-Months Of Weight Maintenance Subsequent To Weight Loss, James D. Lecheminant, Bryan K. Smith, Eric C. Westman, Mary C. Vernon, Joseph E. Donnelly

Faculty Publications

Objectives: This study compared LDL, HDL, and VLDL subclasses in overweight or obese adults consuming either a reduced carbohydrate (RC) or reduced fat (RF) weight maintenance diet for 9 months following significant weight loss. Methods: Thirty-five (21 RC; 14 RF) overweight or obese middle-aged adults completed a 1-year weight management clinic. Participants met weekly for the first six months and bi-weekly thereafter. Meetings included instruction for diet, physical activity, and behavior change related to weight management. Additionally, participants followed a liquid very low-energy diet of ~2092 kJ per day for the first three months of the study. Subsequently, participants followed …

Should Health Policy Focus On Physical Activity Rather Than Obesity?, Richard Weller, Emmanuel Stamatakis, Steven N. Blair, Timothy P. Gill, Louise A. Baur, Lesley A. King

Faculty Publications

No abstract provided.

Advancing The Future Of Physical Activity Guidelines In Canada: An Independent Expert Panel Interpretation Of The Evidence, Antero Kesäniemi, Chris J. Riddoch, Bruce Reeder, Steven N. Blair, Thorkild I. A. Sørensen

Faculty Publications

The Canadian Society for Exercise Physiology, in partnership with the Public Health Agency of Canada, has initiated a review of their physical activity guidelines to promote healthy active living for Canadian children, youth, adults and older adults; previous guidelines were released in 2002, 2002, 1998 and 1999 respectively. Several background papers from this project were published recently and provide foundation evidence upon which to base new guidelines. Furthermore, comprehensive systematic reviews were completed to ensure a rigorous evaluation of evidence informing the revision of physical activity guidelines for asymptomatic populations. The overall guideline development process is being guided and assessed …

Siamese Cooperates With The Cdh1-Like Protein Ccs52a1 To Establish Endoreplication In Arabidopsis Thaliana Trichomes, Remmy Kasili, Jason D. Walker, L. Alice Simmons, Jing Zhou, Lieven De Veylder, John C. Larkin

Faculty Publications

Endoreplication, also known as endoreduplication, is a phyogenetically widespread modified version of the cell cycle in which DNA replication is not followed by cell division. The SIAMESE (SIM) gene of Arabidopsis thaliana encodes the founding member of a novel class of plant-specific cyclin-dependent kinase (CDK) inhibitors and is a key regulator of endoreplication during the development of trichomes (shoot epidermal hairs). Here, we have identified mutations in the CCS52A1 gene as genetic modifiers of the multicellular trichome phenotype of sim mutants. Loss-of-function ccs52A1 mutations dramatically enhance the multicellularity of sim mutants trichomes in double mutants, whereas overexpression of CCS52A1 completely …

Inheritance Of Traits Associated With Phosphorus Utilization Efficiency In Maize, Roberto Fritsche-Neto, Glauco Vieira Miranda, Rodrigo Oliveira Delima, Leandro Vagno De Souza, Jaeveson Da Silva

Faculty Publications

The objective of this work was to determine the genetic effects that control the inheritance of characters associated with the phosphorus utilization efficiency (PUE) in maize, and to determine the relationship among them. A diallel between six maize cultivars was performed and 15 hybrid combinations were obtained from it. These cultivars were evaluated in high and low phosphorus availability in the greenhouse and field. Plant response to nutrient availability (RU) and traits associated to utilization and translocation efficiency were measured. There were significant interactions between hybrid combinations and phosphorus availability for plant dry matter mass (MSP), P concentration in plants …

Perimenopausal Obesity, Colleen Keller, Linda Larkey, Johanna K. Distefano, Edna Boehm-Smith, Kathie Records, Alyssa G. Robillard, Sharry Veres, Manal Al-Zadjali, Anne-Marie O'Brian

Faculty Publications

Obesity is recognized as one of the most important underlying risk factors for a wide variety of diseases, including heart disease and diabetes. Women are particularly prone to obesity, and approaches that address life transitions across the life span suggest that a number of factors may converge at passage points, such as menopause, that contribute to weight accumulation in the aging woman. The menopausal phase of a woman's life brings a number of changes that may trigger and maintain weight gain. Although the prevalence of overweight and obesity is attributable to each of these factors, it is most likely the …