Digital Commons Network^™

Effect Of Different Doses Of Aerobic Exercise On Total White Blood Cell (Wbc) And Wbc Subfraction Number In Postmenopausal Women: Results From Drew, Neil M. Johannsen, Damon L. Swift, William D. Johnson, Vishwa D. Dixit, Conrad P. Earnest, Steven N. Blair, Timothy S. Church

Faculty Publications

Background: Elevated total white blood cell (WBC) count is associated with an increased risk of coronary heart disease and death. Aerobic exercise is associated with lower total WBC, neutrophil, and monocyte counts. However, no studies have evaluated the effect of the amount of aerobic exercise (dose) on total WBC and WBC subfraction counts.

Purpose: To examine the effects of 3 different doses of aerobic exercise on changes in total WBC and WBC subfraction counts and independent effects of changes in fitness, adiposity, makers of inflammation (IL-6, TNF-α, C-reactive protein), fasting glucose metabolism, and adiponectin.

Methods: Data from 390 sedentary, overweight/obese …

Comparing The Validity Of 2 Physical Activity Questionnaire Formats In African-American And Hispanic Women, Louise C. Mâsse, Janet E. Fulton, Kathleen B. Watson, Susan Tortolero, Harold W. Kohl Iii, Michael C. Meyers, Steven N. Blair, William W. Wong

Faculty Publications

Background: The purpose of this study was to compare the validity of 2 physical activity questionnaire formats - one that lists activities (Checklist questionnaire) and one that assesses overall activities (Global questionnaire) by domain.

Methods: Two questionnaire formats were validated among 260 African-American and Hispanic women (age 40-70) using 3 validation standards: 1) accelerometers to validate activities of ambulation; 2) diaries to validate physical activity domains (occupation, household, exercise, yard, family, volunteer/church work, and transportation); and 3) doubly-labeled water to validate physical activity energy expenditure (DLW-PAEE).

Results: The proportion of total variance explained by the Checklist questionnaire was 38.4% with …

Systematic Review Of Peer Support For Breastfeeding Continuation: Metaregression Analysis Of The Effect Of Setting, Intensity, And Timing, Kate Jolly, Lucy Annang Ingram Phd, Khalid S. Khan, Jonathan J. Deeks, Nick Freemantle, Christine Macarthur

Faculty Publications

OBJECTIVE: To examine the effect of setting, intensity, and timing of peer support on breast feeding. DESIGN: Systematic review and metaregression analysis of randomised controlled trials. DATA SOURCES: Cochrane Library, Medline, CINAHL, the National Research Register, and British Nursing Index were searched from inception or from 1980 to 2011. Review methods Study selection, data abstraction, and quality assessment were carried out independently and in duplicate. Risk ratios and 95% confidence intervals were calculated for individual studies and pooled. Effects were estimated for studies grouped according to setting (high income countries, low or middle income countries, and the United Kingdom), intensity …

Exploratory Study On Explanations And Theories Of How Telecentres And Other Community-Based E-Inclusion Actors Operate And Have An Impact On Digital And Social Inclusion Policy Goals, M. Garrido, A. Sey, Tabitha B. Hart, L. Santana

Faculty Publications

This report includes the results of the research project ‘Exploratory study on explanations and theories of how Telecentres and other community-based e-Inclusion actors operate and have an impact on digital and social inclusion policy goals’. This study was commissioned by IPTS to feed into a forthcoming 2-year research project: Measuring the impact of eInclusion actors on Digital Literacy, Skills and Inclusion goals (MIREIA). The literature review presented in this report was designed to capture the theories and explanations represented in the existing body of research in order to: provide a comprehensive and multidisciplinary landscape on theories and analytical frameworks; analyze …

A Comparative Study Of Prospective Natural Gas For Vehicle (Ngv) Buyers' Behavior Intention In Thailand, Howard W. Combs, N. Likitsuwannakool, S. Chaipoopirutana

Faculty Publications

This study examines the prospects of how Natural Gas Vehicles (NGV) could gain more popularity, and more consumers, throughout Thailand. A survey of 500 potential consumers, comprising l00 respondents in each of the five separate regions, identified relevant geographic locations, demographic factors and their impact on behavior intention. The results of the study suggest that consumer’s behavioral intentions toward NGV are affected by factors pertaining to social influences and NGV attributes. Each group contains several sub-variables and is used in verifying its individual impact on consumer’s behavioral intention, while the differences in vehicle factors did not strongly affect the behavior …

Short-Term Carbon Partitioning Fertilizer Responses Vary Among Two Full-Sib Loblolly Pine Clones, Jeremy P. Stovall, John R. Seiler, Thomas R. Fox

Faculty Publications

We investigated the effects of fertilizer application on the partitioning of gross primary productivity (GPP) between contrasting full-sib clones of Pinus taeda (L.). Our objective was to determine if fertilizer growth responses resulted from similar short-term changes to partitioning. A modeling approach incorporating respiratory carbon (C) fluxes, soil CO2 efflux (FS), and biomass was applied to a factorial design with two clones, fertilizer and control treatments, and four sequential monthly harvests of seedlings planted in a greenhouse. Partitioning was integrated over 121 days to above, belowground, and total net primary production (ANPP + BNPP = NPP), total belowground C flux …

The Drugs Stop Here: A Public Health Framework To Address The Drug Shortage Crisis, Sharona Hoffman

Faculty Publications

Drug shortages are emerging as a major public health threat. Grave concern has been expressed by the medical community and government officials, and the crisis has been highlighted in recent media stories. Nevertheless, little has been written to date in the legal literature about the drug shortage crisis, and this timely article begins to fill this gap. It provides a thorough analysis of the origins and implications of the drug shortage problem and formulates a multi-layered approach to addressing it. The article argues that drug shortages result from a combination of market failures and regulatory constraints. It proposes a blend …

Planning For The Next Century Or The Next Week, Whichever Comes First, Erik M. Jensen

Faculty Publications

I look at long term planning in law schools.

What Is The Meaning Of Health? Constitutional Implications Of Defining 'Medical Necessity' And 'Essential Health Benefits' Under The Affordable Care Act, B. Jessie Hill

Faculty Publications

One consequence of the Affordable Care Act (ACA) is that government will come to play a more extensive role in healthcare decision-making by individuals and their providers. The ACA does not directly regulate access to health services, but by means of a system of funding, mandates, and penalties, it essentially requires many employers to provide, and most individuals to carry, a certain minimum level of health insurance. Governmental decisions about which medical services qualify as medically necessary and appropriate may take on a new and greater importance, because government officials will be required to decide what sorts of procedures must …

Retrotransposons As A Major Source Of Epigenetic Variations In The Mammalian Genome, Muhammad B. Ekram, Keunsoo Kang, Hana Kim, Joomyeong Kim

Faculty Publications

Transcription of retrotransposons is usually repressed by DNA methylation, but a few elements, such as intracisternal A-particles (IAPs) associated with the Agouti and Axin-fused loci, partially escape this repression mechanism. The levels of this repression are also variable among individuals with an identical genome sequence, generating epigenetically different states of loci or epialleles. In the current study, we tested the existence of additional retrotransposon-derived epialleles in the mouse genome. Using a series of bioinformatics approaches, 143 candidate epialleles were first identified from the mouse genome based on their promoter activity and association with active histone modification marks. Detailed analyses suggest …

Contextual Chemosensory Urine Signaling In An African Cichlid Fish, Karen P. Maruska, Russell D. Fernald

Faculty Publications

Chemosensory signaling is crucial for communication in many fish species, but little is known about how signalers modulate chemical output in response to sensory information and social context. Here, we tested the hypothesis that dominant male African cichlid fish (Astatotilapia burtoni) use urine signals during social interactions, and demonstrate that this signaling depends on social context (reproductive; territorial) and on available sensory information (visual cues; full interaction). We injected males with dye to visualize urine pulses and exposed them to full sensory information or visual cues alone of four types: (1) dominant male; (2) gravid (reproductively receptive) females; (3) mouth-brooding …

Variants In Cxadr And F2rl1 Are Associated With Blood Pressure And Obesity In African-Americans In Regions Identified Through Admixture Mapping, Priya B. Shetty, Hua Tang, Bamidele O. Tayo, Alanna C. Morrison, Craig L. Hanis, Dabeeru C. Rao, Jeffery H. Young, Ervin R. Fox, Eric Boerwinkle, Richard S. Cooper, Neil J. Risch, Xiaofeng Zhu

Faculty Publications

OBJECTIVE: Genetic variants in 296 genes in regions identified through admixture mapping of hypertension, BMI, and lipids were assessed for association with hypertension, blood pressure (BP), BMI, and high-density lipoprotein cholesterol (HDL-C). METHODS: This study identified coding SNPs identified from HapMap2 data that were located in genes on chromosomes 5, 6, 8, and 21, wherein ancestry association evidence for hypertension, BMI, or HDL-C was identified in previous admixture mapping studies. Genotyping was performed in 1733 unrelated African-Americans from the National Heart, Lung and Blood Institute's Family Blood Pressure Project, and gene-based association analyses were conducted for hypertension, SBP, DBP, BMI, …

Offspring Production With Cryopreserved Sperm From A Live-Bearing Fish Xiphophorus Maculatus And Implications For Female Fecundity, Huiping Yang, Markita G. Savage, Leona Hazlewood, Ronald B. Walter, Terrence R. Tiersch

Faculty Publications

Xiphophorus fishes are well-established models for biomedical research of spontaneous or induced tumors, and their use in research dates back to the 1930s. Currently, 58 well-pedigreed lines exist among 24 Xiphophorus species housed as live animals at the Xiphophorus Genetic Stock Center. The technique of sperm cryopreservation has been applied to preserve these valuable genetic resources, and production of offspring has been reported with cryopreserved sperm in two species (X. helleri and X. couchianus). The goal of this research was to establish protocols for sperm cryopreservation and artificial insemination that yield live young in X. maculatus, a widely used research …

Development Of Cantaloupe (Cucumis Melo) Juice Powders Using Spray Drying Technology, Kevin Mis Solval, Srijanani Sundararajan, Luis Alfaro, Subramaniam Sathivel

Faculty Publications

Cantaloupes are a good source of carotenoids and vitamin C. Cantaloupe fruit juice powder containing vitamin C and β-carotene can be produced by spray drying. The objective of this study was to develop cantaloupe fruit juice (CJ) powder and to evaluate its nutritional and physical properties. Fresh cantaloupe fruits purchased from a local store were diced and juiced. CJ with 10% maltodextrin (MD) added was spray dried at inlet temperatures of 170, 180 and. /or 190 °C. Three spray dried cantaloupe powders, including CJ dried with MD at 170 °C (CJP1), CJ dried with MD at 180 °C (CJP2), CJ …

Overexpression Of Arabidopsis And Rice Stress Genes' Inducible Transcription Factor Confers Drought And Salinity Tolerance To Rice, Karabi Datta, Niranjan Baisakh, Moumita Ganguly, Sellapan Krishnan, Kazuko Yamaguchi Shinozaki, Swapan K. Datta

Faculty Publications

Rice yield is greatly affected by environmental stresses such as drought and salinity. In response to the challenge of producing rice plants tolerant to these stresses, we introduced cDNA encoding the transcription factors DREB1A and DREB1B under the control of the stress inducible rd29 promoter. Two different indica rice cultivars were used, BR29, an improved commercially cultivated variety from Bangladesh and IR68899B, an IRRI bred maintainer line for hybrid rice. Agrobacterium mediated transformation of BR29 was done independently with DREB1A isolated from rice and Arabidopsis and DREB1B isolated from rice, whereas biolistic transformation was done with rice- DREB1B in the …

Tracing The Evolution Of Chiropractic Students’ Confidence In Clinical And Patient Communication Skills During A Clinical Internship: A Multi-Methods Study, Mark Hecimovich, Simone Volet

Faculty Publications

Background: Anecdotal evidence points to variations in individual students’ evolving confidence in clinical and patient communication skills during a clinical internship. A better understanding of the specific aspects of internships that contribute to increasing or decreasing confidence is needed to best support students during the clinical component of their study.

Methods: A multi-method approach, combining two large-scale surveys with 269 students and three in-depth individual interviews with a sub-sample of 29 students, was used to investigate the evolution of change in student confidence during a 10-month long internship. Change in levels of confidence in patient communication and clinical skills was …

Effects Of Walnut Consumption On Cognitive Performance In Young Adults, Peter Pribis, Rudolph N. Bailey, Andrew A. Russell, Marcia A. Kilsby, Magaly Hernandez, Winston J. Craig, Tevni Grajales, David J. Shavlik, Joan Sabatè

Faculty Publications

Walnuts contain a number of potentially neuroprotective compounds like vitamin E, folate, melatonin, several antioxidative polyphenols and significant amounts of n-3 α-linolenic fatty acid. The present study sought to determine the effect of walnuts on verbal and non-verbal reasoning, memory and mood. A total of sixty-four college students were randomly assigned to two treatment sequences in a crossover fashion: walnuts-placebo or placebo-walnuts. Baseline data were collected for non-verbal reasoning, verbal reasoning, memory and mood states. Data were collected again after 8 weeks of intervention. After 6 weeks of washout, the intervention groups followed the diets in reverse order. Data were …

An Instructional Pyramid: Expanding Coach Wooden's "Pyramid Of Success" To Guide P.E.T.E. Professionals, Robert Christenson, David C. Barney

Faculty Publications

What in the teaching-learning process can PETE (Physical Education Teacher Education) faculty identify as being effective and a critical part of this multifaceted practice? Which of the physical activity learning experiences best serves the student? Finally, how does a future-professional physical education teacher, who is inexperienced and intimidated by their first job circumstances, wade through all the information and responsibilities to perform up to expectations? As described by Veal (2011), "Teachers operate in an intensely complicated and demanding world. They face 30 or more students at once – each one different from the other, demanding individualized attention and treatment. Teachers …

Influences On Active Family Leisure And A Healthy Lifestyle Among Adolescents, Shallie M. Taylor, Peter Ward, Ramon Zabriskie, Brian Hill, Carl Hanson

Faculty Publications

The purpose of this study was to examine how attitude, subjective norm, and perceived behavioral control influence adolescents’ intent to participate in active family leisure within the theory of plan behavior framework. Adolescents (N = 472) completed an online questionnaire about their perceptions and actual participation in active family leisure. Structural equation modeling was used to analyze the data. A post-hoc analysis also considered individual leisure and its role on active family leisure. Attitude, subjective norm, and perceived behavioral control were significant predictors of intent to participate in active family leisure.

Development Of Clinical Ethics Services In The Uk: A National Survey, Anne Marie Slowther, Leah Mcclimans, Charlotte Price

Faculty Publications

Background In 2001 a report on the provision of clinical ethics support in UK healthcare institutions identified 20 clinical ethics committees. Since then there has been no systematic evaluation or documentation of their work at a national level. Recent national surveys of clinical ethics services in other countries have identified wide variation in practice and scope of activities.

Objective To describe the current provision of ethics support in the UK and its development since 2001.

Method A postal/electronic questionnaire survey administered to the chairs of all 82 clinical ethics services registered with the UK Clinical Ethics Network in July 2010. …

Report And Reflections From Year One Of The Nsf Gk- 12 Program At Usm, Sherry S. Herron, J. Hanna, K. Wingo

Faculty Publications

No abstract provided.

Environmental Perceptions And Objective Walking Trail Audits Inform A Community-Based Participatory Research Walking Intervention, Jamie Zoellner, Jennie L. Hill, Karen Zynda, Alicia D. Sample, M. Kathleen Yadrick

Faculty Publications

Background: Given the documented physical activity disparities that exist among low-income minority communities and the increased focused on socio-ecological approaches to address physical inactivity, efforts aimed at understanding the built environment to support physical activity are needed. This community-based participatory research (CBPR) project investigates walking trails perceptions in a high minority southern community and objectively examines walking trails. The primary aim is to explore if perceived and objective audit variables predict meeting recommendations for walking and physical activity, MET/minutes/week of physical activity, and frequency of trail use. Methods: A proportional sampling plan was used to survey community residents in this …

Developing Positive Attitudes Toward Geriatric Nursing Among Millennials And Generations Xers, Barbara A. Heise, Vickie Johnsen, Deborah O. Himes, Debra Wing

Faculty Publications

Despite the increase of the older adult population, there exists a shortage of health care professionals trained to help this population remain independent as long as possible. Ageism, common among younger adults, affects the capacity building of health care for older adults. Research has indicated that increased knowledge about older adults, as well as exposure to the elderly, may alter nursing students' attitudes regarding careers in gerontological nursing. However, questions remain as to what are the most effective ways to provide gerontological content in nursing programs and enhance attitudes toward older adults. With the understanding that younger adults see a …

Giving Birth: The Voices Of Women In Tamil Nadu, India, Cheryl A. Corbett, Lynn Clark Callister

Faculty Publications

Purpose: The purpose of this qualitative descriptive study is to describe the perceptions of childbearing women living in Tamil Nadu, India. This study can increase cultural understanding and foster cultural competence in nurses caring for Indian women.

Study Design and Methods: Women were invited to share their childbearing experiences. Following institutional review board approval, interviews were held with 22 women who had given birth in the previous 18 months to a viable infant. The women were grateful for the opportunity to share their perspectives with an interested nurse investigator. Data collection proceeded concurrently with data analysis. Themes were generated collaboratively …

Feminism In The Global Political Economy: Contradiction And Consensus In Cuba, Deborah M. Weissman

Faculty Publications

No abstract provided.

Important Information Literacy Standards For Life And Health Sciences, Betsy S. Hopkins

Faculty Publications

Information literacy in the life and health sciences is a dynamic field, with challenges, opportunities, and rewards for the successful practitioner. This chapter will describe the big picture of information literacy in these disciplines, list relevant performance indicators from the ALA/ACRL/STS Task Force on Information Literacy for Science and Technology [STS-TFILST] (2006) Information Literacy Standards for Science and Technology (hereafter Standards), and give some practical advice for life and health sciences librarians and librarians with instructional responsibilities in those disciplines. The focus is on undergraduates at research universities, although many principles and strategies will apply to other circumstances.

Social Relationships And Mortality, Julianne Holt-Lunstad, Timothy B. Smith

Faculty Publications

Social relationships benefit not only mental health but also physical health. This review addresses the following questions: (1) What is the overall magnitude of the effect of social relationships on risk for premature death? (2) How generalized is the effect and are there factors known to influence this association? (3) What are the likely pathways by which social relationships influence longevity? The article concludes by discussing the implications of these findings for potential interventions aimed at reducing risk for mortality.

Prevalence And Determinants For Overweight And Obesity Among Residents Of A Mining Township In Kitwe, Zambia, In 2011: A Population-Based Survey, Cosmas Zyaambo, Olesegun Babaniyi, Peter Songolo, Adamson S. Muula, Emmanuel Rudatsikira, Victor M. Mukonka, Seter Siziya

Faculty Publications

Background: Obesity and overweight in Africa have been attributed to demogra- phic and nutritional changes that have resulted from urbanization and sedentary lifestyles and increased caloric intake without much physical activities. This has put populations at an increased risk of cardiovascular diseases, Diabetes mellitus, osteoarthritis, dyslipidemia, and cancer. The objective of this study was to deter- mine the prevalence and associated factors for combined overweight and obesity among residents of a mining town, Kitwe, in Zambia.

Methods: A cross sectional study was conducted using a modified WHO glo- bal Non Communicable Diseases Surveillance Initiative STEPs 1 and 2 method of …

Transcriptomic Profiles Of Peripheral White Blood Cells In Type Ii Diabetes And Racial Differences In Expression Profiles, Jinghe Mao, Junmei Ai, Xinchun Zhou, Ming Shenwu, Manuel Ong Jr., Marketta Blue, Jasmine T. Washington, Xiaonan Wang, Youping Deng

Faculty Publications

Background: Along with obesity, physical inactivity, and family history of metabolic disorders, African American ethnicity is a risk factor for type 2 diabetes (T2D) in the United States. However, little is known about the differences in gene expression and transcriptomic profiles of blood in T2D between African Americans (AA) and Caucasians (CAU), and microarray analysis of peripheral white blood cells (WBCs) from these two ethnic groups will facilitate our understanding of the underlying molecular mechanism in T2D and identify genetic biomarkers responsible for the disparities.

Results: A whole human genome oligomicroarray of peripheral WBCs was performed on 144 …

Protocol For The Modeling The Epidemiologic Transition Study: A Longitudinal Observational Study Of Energy Balance And Change In Body Weight, Diabetes And Cardiovascular Disease Risk, Amy Luke, Pascal Bovet, Terrence E. Forrester, Estelle V. Lambert, Jacob Plange-Rhule, Dale A. Schoeller, Lara R. Dugas, Ramon A. Durazo-Arvizu, David Shoham, Richard S. Cooper, Soren Brage, Ulf Ekelund, Nelia P. Steyn

Faculty Publications

Background: The prevalence of obesity has increased in societies of all socio-cultural backgrounds. To date, guidelines set forward to prevent obesity have universally emphasized optimal levels of physical activity. However there are few empirical data to support the assertion that low levels of energy expenditure in activity is a causal factor in the current obesity epidemic are very limited. Methods/Design. The Modeling the Epidemiologic Transition Study (METS) is a cohort study designed to assess the association between physical activity levels and relative weight, weight gain and diabetes and cardiovascular disease risk in five population-based samples at different stages of economic …