Digital Commons Network^™

Cryo-Em Structure Of A Photosystem I Variant Containing An Unusual Plastoquinone Derivative In Its Electron Transfer Chain, Christopher J. Gisriel, Vasily Kurashov, David F. Iwig, Brandon P. Russell, David J. Vinyard, Gary W. Brudvig, John H. Golbeck, K. V. Lakshmi

Faculty Publications

Photosystem I (PS I) is a light-driven oxidoreductase responsible for converting photons into chemical bond energy. Its application for renewable energy was revolutionized by the creation of the MenB deletion (ΔmenB) variant in the cyanobacterium Synechocystis sp. PCC 6803, in which phylloquinone is replaced by plastoquinone-9 with a low binding affinity. This permits its exchange with exogenous quinones covalently coupled to dihydrogen catalysts that bind with high affinity, thereby converting PS I into a stable solar fuel catalyst. Here, we reveal the 2.03-Å-resolution cryo-EM structure of a recent MenB variant of PS I. The quinones and their binding environment are …

Human Capital Assessment In Indigenous Regions To Enable Sustainable Futures, Victoria N. Sharakhmatova, Elena G. Mikhailova

Faculty Publications

This study is dedicated to the economic valuation of human capital (HC) in the regions where the Indigenous peoples of Kamchatka reside. The entire Kamchatksky Krai is considered an Indigenous people’s ancestral territory. However, in this study, only municipalities whose population is more than one-third Indigenous were chosen for the assessment. This includes six municipal districts and one urban district (Aleytsky, Bystrinsky, Karaginsky, Olyutorsky, Penzhinsky, and Tigilsky municipal districts and Palana urban district). The study employs statistical analysis and integrated, situational approaches: the investment approach was deemed the most appropriate tool for the economic assessment of HC in Indigenous territories. …

“How Come I Don’T Look Like That”: The Negative Impact Of Wishful Identification With Influencers On Follower Well-Being, Ruonan Zhang, Trinideé Mercado, Yu Chen, Nicky Chang Bi

Faculty Publications

Purpose Building on Social Comparison Theory and Parasocial Relationship Theory, this study is designed to investigate how followers’ wishful identification with YouTube influencers is associated with their psychological well-being and how parasocial relationships with influencers moderate this association. Design/methodology/approach Influencer-fan data (N = 504) is collected through a Qualtrics survey in collaboration with a real-life influencer on YouTube. Hayes Process Modeling was used to conduct mediation and moderation analyses. Findings Results indicate that enjoyment of influencers’ videos positively leads to followers’ wishful identification, which negatively impacts their well-being. The parasocial relationship with the influencer was found to be a significant …

Mediator Kinase Inhibitors Suppress Triple-Negative Breast Cancer Growth And Extend Tumor Suppression By Mtor And Akt Inhibitors, Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor Roninson, Eugenia Broude

Faculty Publications

Triple-negative breast cancers (TNBC) are treated primarily by chemotherapy and lack clinically validated therapeutic targets. In particular, inhibitors of the PI3K/AKT/mTOR pathway, abnormally activated in many breast cancers, failed to achieve clinical efficacy in TNBC due to the development of adaptive drug resistance, which is largely driven by the transcriptomic plasticity of TNBC. Expression of CDK8/19 Mediator kinases that control transcriptional reprogramming correlates with relapse-free survival and treatment failure in breast cancer patients, including TNBC. We now investigated how CDK8/19 inhibitors affect the growth of TNBC tumors and their response to mTOR and AKT inhibitors. In contrast to the effects …

Strategies To Alleviate Flickering: Bayesian And Smoothing Methods For Deep Learning Classification In Video, Noah Miller, Glen Ryan Drumm, Lance Champagne, Bruce A. Cox, Trevor Bihl

Faculty Publications

Excerpt: Increasing reliance on autonomous systems requires confidence in the accuracies produced from computer vision classification algorithms. Computer vision (CV) for video classification provides phenomenal abilities, but it often suffers from “flickering” of results. Flickering occurs when the CV algorithm switches between declared classes over successive frames. Such behavior causes a loss of trust and confidence in their operations.

Sound Innovations For Biofabrication And Tissue Engineering, Mengxi Wu, Zhiteng Ma, Zhenhua Tian, Joseph Rich, Xin He, Jianping Xia, Ye He, Kaichun Yang, Shujie Yang, Kam W. Leong, Luke P. Lee, Tony Jun Huang

Faculty Publications

Advanced biofabrication techniques can create tissue-like constructs that can be applied for reconstructive surgery or as in vitro three-dimensional (3D) models for disease modeling and drug screening. While various biofabrication techniques have recently been widely reviewed in the literature, acoustics-based technologies still need to be explored. The rapidly increasing number of publications in the past two decades exploring the application of acoustic technologies highlights the tremendous potential of these technologies. In this review, we contend that acoustics-based methods can address many limitations inherent in other biofabrication techniques due to their unique advantages: noncontact manipulation, biocompatibility, deep tissue penetrability, versatility, precision …

Time Domain Spectral Lidar Enabled By Cascaded Raman In A Hydrogen-Filled Transmitter, Richard K. Martin, Trevor L. Courtney, Arielle M. Adams, Daniel E. Leaird, Luke Ausley, Christian K. Keyser

Faculty Publications

We introduce what we believe to be novel spectral light detection and ranging (LiDAR) architectures that enable ultra-compact systems by a transition from spectral signal processing in space (gratings) to processing in time. The architectures leverage temporal dispersion and the unique spectro-temporal waveforms produced from the cascaded Raman scattering generated in the (H₂) filled hollow core fiber. The characterized Raman source yields as many as six Raman orders from 1.06-1.70 μm; their unique spectro-temporal waveforms are measured. System performance simulations based on measured Raman waveforms show that high accuracy measurement of range and reflectivity are possible with proper …

Limitations Of Beam-Control Compensation, Matthew Kalensky, Darren Getts, Matthias T. Banet, Derek J. Burrell, Milo W. Hyde, Mark F. Spencer

Faculty Publications

In this paper, we use wave-optics simulations to explore the limitations of beam-control compensation. We evaluate performance in terms of the normalized power in a diffraction-limited bucket for the cases of no beam-control compensation, perfect phase compensation, and perfect full-field compensation. From these results, we are able to arrive at the following conclusions: (1) without any form of beam-control compensation, performance begins to degrade when D/r₀ > 1; (2) with perfect phase compensation, performance begins to degrade when D/r₀ > 1 and (λ/r₀)/θ₀ > 1; and (3) with perfect full-field compensation, performance begins to degrade when D/r_{0 …}

Ultra-Relativistic Electron Flux Enhancement Under Persistent High Speed Solar Wind Stream, L R. Alves, L A. Da Silva, V Deggeroni, J P. Marchezi, P R. Jauer, G B D Silva, D G. Sibeck

Faculty Publications

The physical mechanisms usually applied to explain the relativistic electron enhancement have been delved into to elucidate non-adiabatic electron acceleration resulting in the ultra-relativistic electron population observed in the outer radiation belt. We considered multisatellite observations of the solar wind parameters, magnetospheric waves, and particle flux to report an unusual local acceleration of ultra-relativistic electrons under a prolonged high-speed solar wind stream (HSS). A corotating interaction region reaches the Earth’s bowshock on August 3, 2016, causing a minor geomagnetic storm. Following this, the magnetosphere was driven for 72 h by a long-term HSS propagating at 600 km/s. During this period, …

Ultra-Relativistic Electron Flux Enhancement Under Persistent High Speed Solar Wind Stream, L R. Alves, L A. Da Silva, V Deggeroni, J P. Marchezi, P R. Jauer, G B D Silva, D G. Sibeck

Faculty Publications

The physical mechanisms usually applied to explain the relativistic electron enhancement have been delved into to elucidate non-adiabatic electron acceleration resulting in the ultra-relativistic electron population observed in the outer radiation belt. We considered multisatellite observations of the solar wind parameters, magnetospheric waves, and particle flux to report an unusual local acceleration of ultra-relativistic electrons under a prolonged high-speed solar wind stream (HSS). A corotating interaction region reaches the Earth’s bowshock on August 3, 2016, causing a minor geomagnetic storm. Following this, the magnetosphere was driven for 72 h by a long-term HSS propagating at 600 km/s. During this period, …

Exploring In-Service Science Teachers' Self-Perceptions Of Competence And Pedagogical Approaches To Socioscientific Issues In Education, Arberore Bicaj, Fatlume Berisha, Rachel Gisewhite

Faculty Publications

Global education experts are increasingly prioritizing scientific literacy development. Science education is key to enhancing scientific literacy, fostering social responsibility, and supporting economic growth by equipping individuals with essential scientific knowledge and skills. In the past two decades, socioscientific issues (SSI) have greatly influenced science education research, improving students’ ability to apply scientific knowledge in real-world contexts and advancing functional scientific literacy. Given the strong evidence that socioscientific issues (SSI) enhance scientific literacy and social responsibility skills, understanding SSI role in science education is crucial for developing countries aiming to boost economic and social growth. This research aimed to understand …

From "Open Ocean" To "Exposed Aquaculture": Why And How We Are Changing The Standard Terminology Describing "Offshore Aquaculture", Tyler Sclodnick, Michael Chambers, Barry Antonio Costa-Pierce, Tobias Dewhurst, Nils Goseberg, Kevin Gerald Heasman, Wolf Isbert, Gesche Krause, Daniel Wieczorek, Till Markus, Bela H. Buck

Faculty Publications

The term “offshore” with regards to aquaculture has hitherto encompassed various perspectives, including technology, geographic location, legal jurisdiction, and more. To resolve the ambiguity in this term and understand its implications for current and future aquaculture development, “offshore” should be resolved into two separate metrics: distance from shore and energy exposure. The United Nations Convention on the Law of the Sea (UNCLOS) distinguishes between internal waters, territorial sea, contiguous zone, exclusive economic zone (EEZ), and the high seas, but currently has no precise definition for “offshore” in its provisions, and therefore no applicable laws pertaining to “offshore” aquaculture. Regulating a …

From "Open Ocean" To "Exposed Aquaculture": Why And How We Are Changing The Standard Terminology Describing "Offshore Aquaculture", Tyler Sclodnick, Michael Chambers, Barry Antonio Costa-Pierce, Tobias Dewhurst, Nils Goseberg, Kevin Gerald Heasman, Wolf Isbert, Gesche Krause, Daniel Wieczorek, Till Markus, Bela H. Buck

Faculty Publications

The term “offshore” with regards to aquaculture has hitherto encompassed various perspectives, including technology, geographic location, legal jurisdiction, and more. To resolve the ambiguity in this term and understand its implications for current and future aquaculture development, “offshore” should be resolved into two separate metrics: distance from shore and energy exposure. The United Nations Convention on the Law of the Sea (UNCLOS) distinguishes between internal waters, territorial sea, contiguous zone, exclusive economic zone (EEZ), and the high seas, but currently has no precise definition for “offshore” in its provisions, and therefore no applicable laws pertaining to “offshore” aquaculture. Regulating a …

Imagination Grows A Better World: Courage, Creativity, And Fantastic Futures, Janet Croft

Faculty Publications

Our field is requiring ever more courage from us as we face challenges to our bedrock beliefs in free access to information and the value of diverse viewpoints, of representation of different ways of being and living, of higher education, and of imagination itself. Where can we find inspiration to keep going? In order to meet the challenges we face with creativity and courage, we need both the ability to imagine a better world and the determination to work to bring this world into being. I’ll talk about some inspirational examples of the pairing of courage and creativity in my …

Properties Of Relativistic Electron Precipitation: A Comparative Analysis Of Wave-Induced And Field Line Curvature Scattering Processes, Luisa Capannolo, Andrew Staff, Wen Li, Katharine Duderstadt, Nithin Sivadas, Joshua Pettit, Sadie Elliot, Murong Qin, Xiao-Chen Shen, Qianli Ma

Faculty Publications

We analyze the properties of relativistic (&gt700 keV) electron precipitation (REP) events measured by the low-Earth-orbit (LEO) POES/MetOp constellation of spacecraft from 2012 through 2023. Leveraging the different profiles of REP observed at LEO, we associate each event with its possible driver: waves or field line curvature scattering (FLCS). While waves typically precipitate electrons in a localized radial region within the outer radiation belt, FLCS drives energy-dependent precipitation at the edge of the belt. Wave-driven REP is detected at any MLT sector and L shell, with FLCS-driven REP occurring only over the nightside–a region where field line stretching is frequent. …

Properties Of Relativistic Electron Precipitation: A Comparative Analysis Of Wave-Induced And Field Line Curvature Scattering Processes, Luisa Capannolo, Andrew Staff, Wen Li, Katharine Duderstadt, Nithin Sivadas, Joshua Pettit, Sadie Elliot, Murong Qin, Xiao-Chen Shen, Qianli Ma

Faculty Publications

We analyze the properties of relativistic (&gt700 keV) electron precipitation (REP) events measured by the low-Earth-orbit (LEO) POES/MetOp constellation of spacecraft from 2012 through 2023. Leveraging the different profiles of REP observed at LEO, we associate each event with its possible driver: waves or field line curvature scattering (FLCS). While waves typically precipitate electrons in a localized radial region within the outer radiation belt, FLCS drives energy-dependent precipitation at the edge of the belt. Wave-driven REP is detected at any MLT sector and L shell, with FLCS-driven REP occurring only over the nightside–a region where field line stretching is frequent. …

Ignis: A One-Dimensional Laminar Flame Code, Jansen P. Berryhill, Jacob K. Spinti, David O. Lignell

Faculty Publications

Laminar flame codes have an important role in combustion modeling. They can provide a fundamental understanding of flame dynamics and provide a basis for building subgrid scale models in turbulent flow simulations. This paper presents Ignis, an open-source laminar flame code with the capability to offload submodels, like soot formation and radiation, using external packages and libraries. Ignis is written in C++, is documented with Doxygen, and is available on GitHub. It contains three different flame formulations: diffusion flames, premixed flames, and laminar flamelets solved in the mixture fraction coordinate. An option to facilitate creation of a diffusion flame table …

Heavy Molecular And Metallic Ions In The Magnetosphere, M Yamauchi, S Christon, I Dandouras, S Haaland, D Kastinen, Lynn M. Kistler, I Mann, S Nozawa, J M C Plane, Y Saito, L Schulz, S Watababe, P Wurz, A W. Yau

Faculty Publications

Observations and present knowledge of heavy ions with mass ≥ 27 in the magnetosphere are reviewed. There are four ultimate sources of these heavy ions: the solar wind (mainly high charge-state atomic ions), the ionosphere (mainly molecular ions), the atmospheric metal layers that originate ultimately from ablation of meteoroids and possibly space debris (low charge-state metallic ions and metal-rich molecular ions), and lunar surface and exosphere (low charge-state metallic and molecular ions). The upstream heavy ions (solar wind origin and lunar origin) give independent information on the ion entry routes to the magnetosphere from proton (H+) and alpha particles (He++): …

Activist Archivists: Centering Marginalized Campus Voices And Rebuilding Institutional Knowledge Through Oral History, Kai H. Uchida

Faculty Publications

The rapidly changing face of the UNH system, retirements spurred by COVID, and a challenging financial environment motivated SCA to restructure the ways that they collect and preserve institutional history. Through a two-year pilot program utilizing a new technology called TheirStory -- which hosts, records, transcribes, and stores interviews -- they began plans to record histories from University leadership, faculty, staff, alumni, and students. This poster recounts how the University Archivist shaped the UNH Oral History Project to fill in the institutional gaps of its past, considers how this project forms a microcosm of his curatorial and collection vision as …

The Roles Of Vicarious Trauma Exposure And Perceived Social Support In Codeine Syrup Misuse Among Black Men Living In Prisons, Jardin Dogan-Dixon, Shawndaya S. Thrasher, Shemeka Thorpe, Paris Wheeler, Danelle Stevens-Watkins

Faculty Publications

Using General Strain Theory, this study investigates the effects of vicarious trauma exposure and perceived social support on nonmedical codeine syrup misuse among Black incarcerated men nearing community re-entry. Data were drawn from the Helping Incarcerated Men project, a study examining mental health, substance misuse, and human immunodeficiency virus (HIV) risk behaviors among Black men living in prisons who were within 180 days of release. A total of 200 Black men self-reported demographics (i.e., age and length of incarceration after age 18), vicarious trauma exposure (e.g., ever witnessing an assault with a weapon and a sudden accidental death), perceived social …

Precision Synthesis Of Conjugated Polymer Films By Surface-Confined Stepwise Sonogashira Cross-Coupling, Sang Gil Youm, Mitchell T. Howell, Chien Hung Chiang, Lu Lu, Neepa M.K. Kuruppu Arachchige, John F. Ankner, Joseph Strzalka, Yaroslav Losovyj, Jayne C. Garno, Evgueni E. Nesterov

Faculty Publications

Thin films of poly(arylene ethynylene)-conjugated polymers, including low-energy-gap donor–acceptor polymers, can be prepared via stepwise polymerization utilizing surface-confined Sonogashira cross-coupling. This robust and efficient polymerization protocol yields conjugated polymers with a precise molecular structure and with nanometer-level control of the organization and the uniform alignment of the macromolecular chains in the densely packed film. In addition to high stability and predictable and well-defined molecular organization and morphology, the surface-confined conjugated polymer chains experience significant interchain electronic interactions, resulting in dominating intermolecular π-electron delocalization which is primarily responsible for the electronic and spectroscopic properties of polymer films. The fluorescent films demonstrate …

Identifying Ordinal Categories For The Water Insecurity Experiences Scales, Edward A. Frongillo Jr., Hilary J. Bethancourt, Joshua D. Miller, Sera L. Young, The Household Water Insecurity Experiences Scales (Hwise)-Research Coordination Network (Rcn)

Faculty Publications

The Household Water Insecurity Experiences (HWISE) and Individual Water Insecurity Experiences (IWISE) Scales are globally suitable tools for comparably measuring water insecurity experiences among households and adults, respectively. The potential range for HWISE and IWISE scores is 0–36. When the WISE Scales were first published, scores of 12 and higher were considered indicative of water insecurity, but additional cut-points are needed to provide more nuanced insights. We therefore sought to develop a practical set of cut-points for the WISE Scales using HWISE data from 13 sites across 12 countries (n = 3,293) and nationally representative samples of IWISE data …

The Sec Spanish Consortium: Foundations For Linguistic Gratuity And Language Documentation Among Latinx Populations In New Destination Communities Of The U.S. South, Stephen Fafulas, Chad Howe, Rafael Orozco, Alicia Cipria, Erin O’Rourke, Nina Moreno, Matthew J. Van Hoose

Faculty Publications

Latinx populations in the USA have grown steadily in recent decades, with significant increases taking place in “new destination communities” of the U.S. South. The focus of our paper is to highlight opportunities for working with these populations, including traditional sociolinguistic ethnographies and community-engaged research. We highlight an initiative named “The SEC Spanish Consortium” which is an interinstitutional collaboration centered on scholarship and service involving Latinx populations in new destination communities of the U.S. South. We show that ongoing and future scholarly work in the U.S. South can act as a mechanism for documenting these emerging Latinx communities while simultaneously …

Editorial Introduction: Policy Actors, Dynamics, And Developments—New Insights From Process Theories And Methodological Applications, Geoboo Song, Gwen Arnold, Melissa K. Merry, Davor Mondom, Ben Galloway, Briana Huett, Camille Gilmore, Saba Siddiki, Holly L. Peterson, Creed Tumlison, Heasun Choi, Meerim Seiitova

Faculty Publications

No abstract provided.

Personhood, Politics, Assisted Reproduction, And The Law Post-Dobbs, Myrisha S. Lewis

Faculty Publications

With the end of the federal constitutional right to abortion, state legislatures and state courts have become far more important in the sphere of reproductive rights. Before Dobbs, anti-abortion advocates had significant (albeit increasingly porous) ceilings on what they could prohibit in relation to reproductive health care. A significant check on those actions is now gone.

In the wake of Dobbs, societal debates about personhood have increased and expanded in terms of their practical implications. Before Dobbs, anti-abortion advocates admitted that Roe and subsequent cases limited the scope of their arguments, especially in relation to the legality …

Privacy Law's Incumbency Problem, Peter Ormerod

Faculty Publications

Policymakers and scholars concerned with the power of informational platforms are questioning how traditional doctrinal silos like privacy law and antitrust law interact in digital markets. Their interaction has taken on new urgency in recent years as states have enacted a flurry of consent-based privacy laws and as digital markets have become increasingly dominated by the same few firms

Contemporary debates about the interaction of competition and privacy tend to ask what role, if any, privacy should play in the antitrust analysis. Little has been written about how new privacy laws shape the competitive landscape. This Article argues that consent-based …

The Power Of All: Tort In The Age Of Constitution, Cristina Carmody Tilley

Faculty Publications

Life in a multicultural nation can be fraught. The United States is a case in point, with hostile tension between members of competing identity groups playing out today on streets, in offices, and across the media. Modern Americans assume that bridging race, gender, and class inequity is the stuff of public—constitutional—law. This assumption follows the lead of modern American lawyers, who migrated to this body of law just as historians, sociologists, and economists began to insist that the private law of tort was exclusively concerned with the accidental physical harms inevitable in a modern economy. According to this econostory, tort …

How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton Ma, Lmsw, Simone Kabarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.

Faculty Publications

Background: The concept of health literacy (HL) is constantly evolving, and social determinants of health (SDoH) have been receiving considerable attention in public health scholarship. Since a 1-size-fits-all approach for HL fails to account for multiple contextual factors and as a result poses challenges in improving literacy levels, there is a need to develop a deeper understanding of the current state of HL and digital health literacy (DHL) research. Objective: This study examined scholars’ conceptualization and scope of work focused on HL and DHL. Methods: Using a search string, investigators (N=2042) focusing on HL, DHL, or both were identified from …

Variations Of Aquaculture Structures, Operations, And Maintenance With Increasing Ocean Energy, Kevin G. Heasman, Nicholas Scott, Tyler Sclodnick, Michael Chambers, Barry Costa-Pierce, Tobias Dewhurst, Wolf Isbert, Bela H. Buck

Faculty Publications

Aquaculture in exposed and/or distant ocean sites is an emerging industry and field of study that addresses the need to improve food security along with the challenges posed by expansion of urban and coastal stakeholders into nearshore and sheltered marine waters. This move necessitates innovative solutions for this industry to thrive in high-energy environments. Some innovative research has increased understanding of the physics, hydrodynamics, and structural requirements enabling the development of appropriate systems. The blue mussel (Mytilus edulis), the New Zealand green shell or green lipped mussel (Perna canaliculus), and the Pacific Oyster (Magallana gigas), are the primary targets for …

Variations Of Aquaculture Structures, Operations, And Maintenance With Increasing Ocean Energy, Kevin G. Heasman, Nicholas Scott, Tyler Sclodnick, Michael Chambers, Barry Costa-Pierce, Tobias Dewhurst, Wolf Isbert, Bela H. Buck

Faculty Publications

Aquaculture in exposed and/or distant ocean sites is an emerging industry and field of study that addresses the need to improve food security along with the challenges posed by expansion of urban and coastal stakeholders into nearshore and sheltered marine waters. This move necessitates innovative solutions for this industry to thrive in high-energy environments. Some innovative research has increased understanding of the physics, hydrodynamics, and structural requirements enabling the development of appropriate systems. The blue mussel (Mytilus edulis), the New Zealand green shell or green lipped mussel (Perna canaliculus), and the Pacific Oyster (Magallana gigas), are the primary targets for …