Digital Commons Network^™

Practitioner Perceptions Regarding The Practices Of Soccer Substitutes, Samuel P. Hills, Jon N. Radcliffe, Martin J. Barwood, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Carlton B. Cooke, Mark Russell

Faculty Publications

Despite empirical observations suggesting that practitioners value the use of substitutions during soccer match-play, limited research has sought to substantiate such claims. This study used online surveys to assess the perceptions of practitioners within professional soccer about the use and practices of substitutes. Thirty-three practitioners completed one of two surveys (each requiring both open and closed questions to be answered), depending upon whether their primary role related mostly to tactical (‘tactical practitioners’; n = 7) or physical (‘physical practitioners’; n = 26) aspects of player/team management. Thematic content analysis of responses identified four higher-order themes: ‘impact of substitutions’, ‘planning and …

Bromodomain And Extraterminal Inhibition By Jq1 Produces Divergent Transcriptional Regulation Of Suppressors Of Cytokine Signaling Genes In Adipocytes, Paula Mota De Sá, Allison J. Richard, Jacqueline M. Stephens

Faculty Publications

© 2019 Endocrine Society 2019. All rights reserved. The Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling pathway has cell-specific functions. Suppressors of cytokine signaling (SOCS) proteins are negative-feedback regulators of JAK-STAT signaling. STAT5 plays a significant role in adipocyte development and function, and bromodomain and extraterminal (BET) proteins may be involved in STAT5 transcriptional activity. We treated 3T3-L1 adipocytes with the BET inhibitor JQ1 and observed that growth hormone (GH)-induced expression of 2 STAT5 target genes from the SOCS family, Socs3 and Cish, were inversely regulated (increased and decreased, respectively) by BET inhibition. Chromatin immunoprecipitation analyses revealed that …

Bromodomain And Extraterminal Inhibition By Jq1 Produces Divergent Transcriptional Regulation Of Suppressors Of Cytokine Signaling Genes In Adipocytes, Paula Mota De Sá, Allison J. Richard, Jacqueline M. Stephens

Faculty Publications

© Endocrine Society 2019. All rights reserved. For permissions, please e-mail: [email protected]. The Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling pathway has cell-specific functions. Suppressors of cytokine signaling (SOCS) proteins are negative-feedback regulators of JAK-STAT signaling. STAT5 plays a significant role in adipocyte development and function, and bromodomain and extraterminal (BET) proteins may be involved in STAT5 transcriptional activity. We treated 3T3-L1 adipocytes with the BET inhibitor JQ1 and observed that growth hormone (GH)-induced expression of 2 STAT5 target genes from the SOCS family, Socs3 and Cish, were inversely regulated (increased and decreased, respectively) by BET inhibition. Chromatin …

Mitochondrial Pyruvate Carriers Are Not Required For Adipogenesis But Are Regulated By High-Fat Feeding In Brown Adipose Tissue, Jasmine A. Burrell, Allison J. Richard, William T. King, Jacqueline M. Stephens

Faculty Publications

© 2020 The Obesity Society. Objective: The objectives of this study were to assess the role of mitochondrial pyruvate carriers (MPCs) in adipocyte development in vitro and determine whether MPCs are regulated in vivo by high-fat feeding in male and female C57BL/6J mice. Methods: This study utilized small interfering RNA-mediated knockdown to assess the requirement of MPC1 for adipogenesis in the 3T3-L1 model system. Treatment with UK-5099, a potent pharmacological MPC inhibitor, was also used to assess the loss of MPC activity. Western blot analysis was performed on adipose tissue samples from mice on a low-fat diet or a high-fat …

Genomic Analysis For Virulence Determinants In Feline Herpesvirus Type-1 Isolates, Andrew C. Lewin, Lyndon M. Coghill, Gillian J. Mclellan, Ellison Bentley, Konstantin G. Kousoulas

Faculty Publications

© 2019, Springer Science+Business Media, LLC, part of Springer Nature. Feline herpesvirus type 1 (FHV-1) is a widespread cause of respiratory and ocular disease in domestic cats. A spectrum of disease severity is observed in host animals, but there has been limited prior investigation into viral genome factors which could be responsible. Stocks of FHV-1 were established from oropharyngeal swabs obtained from twenty-five cats with signs of infection housed in eight animal shelters around the USA. A standardized numerical host clinical disease severity scoring scheme was used for each cat from which an isolate was obtained. Illumina MiSeq was used …

Perinatal Maternal Antibiotic Exposure Augments Lung Injury In Offspring In Experimental Bronchopulmonary Dysplasia, Kent A. Willis, David T. Siefker, Michael M. Aziz, Catrina T. White, Naiha Mussarat, Charles K. Gomes, Amandeep Bajwa, Joseph F. Pierre, Stephania A. Cormier, Ajay J. Talati

Faculty Publications

Copyright © 2020 the American Physiological Society. During the newborn period, intestinal commensal bacteria influence pulmonary mucosal immunology via the gut-lung axis. Epidemiological studies have linked perinatal antibiotic exposure in human newborns to an increased risk for bronchopulmonary dysplasia, but whether this effect is mediated by the gut-lung axis is unknown. To explore antibiotic disruption of the newborn gut-lung axis, we studied how perinatal maternal antibiotic exposure influenced lung injury in a hyperoxia-based mouse model of bronchopulmonary dysplasia. We report that disruption of intestinal commensal colonization during the perinatal period promotes a more severe bronchopulmonary dysplasia phenotype characterized by increased …

Quartz Crystal Microbalance Based Sensor Arrays For Detection And Discrimination Of Vocs Using Phosphonium Ionic Liquid Composites, Stephanie R. Vaughan, Rocío L. Pérez, Pratap Chhotaray, Isiah M. Warner

Faculty Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Herein, we examine two sensing schemes for detection and discrimination of chlorinated volatile organic compounds (VOCs). In this work, phosphonium ionic liquids (ILs) were synthesized and vapor sensing properties examined and compared to phosphonium IL‐polymer composites. Pure IL sensors were used to develop a QCM‐based multisensory array (MSA), while IL‐polymer composites were used to develop an MSA and virtual sensor arrays (VSAs). It was found that by employing the composite MSA, five chlorinated VOCs were accurately discriminated at 95.56%, which was an increase in accuracy as compared to pure ILs MSA …

Synthesis, Characterization, Dna Binding, Topoisomerase Inhibition, And Apoptosis Induction Studies Of A Novel Cobalt(Iii) Complex With A Thiosemicarbazone Ligand, Stephen J. Beebe, Michael J. Celestine, Jimmie L. Bullock, Shayna Sandhaus, Jessa Faye Arca, Donald M. Cropek, Tekettay A. Ludvig, Sydney R. Foster, Jasmine S. Clark, Floyd A. Beckford, Criszcele M. Tano, Elizabeth A. Tonsel-White, Raj K. Gurung, Courtney E. Stankavich, Yuk Ching Tse-Dinh, William L. Jarrett, Alvin A. Holder

Faculty Publications

In this study, 9-anthraldehyde-N(4)-methylthiosemicarbazone (MeATSC) 1 and [Co(phen)₂(O₂CO)]Cl·6H₂O 2 (where phen = 1,10-phenanthroline) were synthesized. [Co(phen)₂(O₂CO)]Cl·6H₂O 2 was used to produce anhydrous [Co(phen)₂(H₂O)₂](NO₃)₃ 3. Subsequently, anhydrous [Co(phen)₂(H₂O)₂](NO₃)₃ 3 was reacted with MeATSC 1 to produce [Co(phen)₂(MeATSC)](NO₃)₃·1.5H₂O·C₂H₅OH 4. The ligand, MeATSC 1 and all complexes were characterized by elemental analysis, FT IR, UV–visible, and multinuclear NMR ( …

Minor Preoccupations, Major Endeavors: The Community Of Poets And Painters, Adelaide M. Russo

Faculty Publications

In Au fond des images (2003), Jean-Luc Nancy introduces concepts about the image, pertinent to understanding the minor genre of poets’ writings on painting. Nancy begins by stating that the image is sacred, clarifying that the sacred should not be confused with the religious, which is based on rituals. The sacred signifies that which is separated, excluded, distanced. The image’s attraction is derived from this, from its untouchable nature. Because of its separation from the viewer, the image inspires a desire for intimacy, and draws the spectator to it. Poets’ texts on painting constitute minor forms: prefaces to catalogs, criticism, …

Plumage Patterns: Ecological Functions, Evolutionary Origins, And Advances In Quantification, Nicholas A. Mason, Rauri C.K. Bowie

Faculty Publications

Birds exhibit remarkable variation in plumage patterns, both within individual feathers and among plumage patches. Differences in the size, shape, and location of pigments and structural colors comprise important visual signals involved in mate choice, social signaling, camouflage, and many other functions. While ornithologists have studied plumage patterns for centuries, recent technological advances in digital image acquisition and processing have transformed pattern quantification methods, enabling comprehensive, detailed datasets of pattern phenotypes that were heretofore inaccessible. In this review, we synthesize recent and classic studies of plumage patterns at different evolutionary and organismal scales and discuss the various roles that plumage …

Metrics To Meet Security & Privacy Requirements With Agile Software Development Methods In A Regulated Environment, Torrey J. Wagner, Thomas C. Ford

Faculty Publications

This work examines metrics that can be used to measure the ability of agile software development methods to meet security and privacy requirements of communications applications. Many implementations of communication protocols, including those in vehicular networks, occur within regulated environments where agile development methods are traditionally discouraged. We propose a framework and metrics to measure adherence to security, quality and software effectiveness regulations if developers desire the cost and schedule benefits of agile methods. After providing an overview of specific challenges that a regulated environment imposes on communications software development, we proceed to examine the 12 agile principles and how …

A Transcriptional Regulatory System Of The S. Cerevisiae Ole1 Gene Responds To Fatty Acid Species And Intracellular Amount, And Not Simply Membrane Status, Marshall Willey, Matthew Ochs, Clara Schriemer, Virginia Mcdonough

Faculty Publications

We examined the effects of unsaturated fatty acid (UFA) species and their concentration on the expression of OLE1, which encodes the stearoyl CoA desaturase, in Saccharomyces cerevisiae. We controlled the amount of UFA taken up by the cell by varying the concentration of tergitol in the medium. When cultured with 1 mM fatty acid in 0.1% tergitol, cells took up much more fatty acid than when cultured with the same concentration of fatty acid at 1% tergitol, although the amount incorporated was dependent on UFA species. For each fatty acid tested, we found that the higher uptake (0.1% tergitol condition) …

Production Of The Polysaccharide Curdlan By Agrobacterium Species On Processing Coproducts And Plant Lignocellulosic Hydrolysates, Thomas P. West

Faculty Publications

This review examines the production of the biopolymer curdlan, synthesized by Agrobacterium species(sp.),on processing coproducts and plant ligno cellulosichydrolysates. Curdlanis a-(1 3)-D-glucan that has various food, non-food and biomedical applications. A number of carbon sources support bacterial curdlan production upon depletion of nitrogen in the culture medium. The influence of culture medium pH is critical to the synthesis of curdlan. The biosynthesis of the-(1 3)-D-glucan is likely controlled by a regulatory protein that controls the genes involved in the bacterial production of curdlan. Curdlan overproducer mutant strains have been isolated from Agrobacterium sp. ATCC 31749 and ATCC 31750 by chemical …

Acquisition And Development Of Verb/Predicate Chaining In Hebrew, Ruth Aronson Berman, Lyle Lustigman

Faculty Publications

The study considers development and use of verb/predicate chaining constructions by Hebrew speakers from early childhood to adolescence, based on analysis of authentic conversational and narrative corpora. Three types of constructions are analyzed, ordered hierarchically by degree of cohesivity and obligatoriness of chaining: (1) monoclausal complex predicates (the “extended predicates” of traditional Hebrew grammars); (2) coreferential interclausal predicate chaining; and (3) discursively motivated topic chaining. Relevant typological features of Modern Hebrew are reviewed as accounting for the absence of canonical clause chaining in the language (the paucity of non-finite constructions in everyday usage, absence of an uninflected basic form of …

Carbon Use Efficiency And Its Temperature Sensitivity Covary In Soil Bacteria, Grace Pold, Luiz A. Domeignoz-Horta, Eric W. Morrison, Serita D. Frey, Seeta A. Sistla, Kristen M. Deangelis

Faculty Publications

The strategy that microbial decomposers take with respect to using substrate for growth versus maintenance is one essential biological determinant of the propensity of carbon to remain in soil. To quantify the environmental sensitivity of this key physiological trade-off, we characterized the carbon use efficiency (CUE) of 23 soil bacterial isolates across seven phyla at three temperatures and with up to four substrates. Temperature altered CUE in both an isolate-specific manner and a substrate-specific manner. We searched for genes correlated with the temperature sensitivity of CUE on glucose and deemed those functional genes which were similarly correlated with CUE on …

Euro-Asian Division Report: Global Church Member Survey 2017-2018, Petr A. Činčala, Pavel Zubkov, Dmitry Fokin, Shannon M. Trecartin

Faculty Publications

This report is the first examination of the Euro-Asian Division 2017-2018 Global Church Member Survey (GCMS) data. The research team worked closely with the meta-analysis team to ensure consistent implementation of the research protocol and consistent use of the questionnaire. A total of 2251 surveys were used from all ESD Unions. The findings of this document are an initial analysis of the data using the latest version of SPSS. The purpose of the Executive Summary is to highlight key findings from the study, which includes: 1. Summarizing the demographic findings in order to describe the characteristics of church members in …

Trans-European Division Report: Global Church Member Survey 2017-2018, Petr A. Činčala, Shannon M. Trecartin, Audrey Andersson

Faculty Publications

This report is the first examination of the Trans-European Division (TED) 2017-2018 Global Church Member Survey (GCMS) data. The research team worked closely with the metaanalysis team to ensure consistent implementation of the research protocol and consistent use of the questionnaire. A total of 1331 surveys were used from all TED Unions. The findings of this document are an initial analysis of the data using the latest version of SPSS. The purpose of the Executive Summary is to highlight key findings from the study, which includes: 1. Summarizing the demographic findings in order to describe the characteristics of church members …

North American Division: Report Global Church Member Survey 2017-2018, Petr A. Činčala

Faculty Publications

This report is the first examination of the North American Division 2017-2018 Global Church Member Survey (GCMS) data. The research team worked closely with the metaanalysis team to ensure consistent implementation of the research protocol and consistent use of the questionnaire. A total of 1,923 surveys were used from all NAD unions. The findings of this document are an initial analysis of the data using the latest version of SPSS. The purpose of the Executive Summary is to highlight key findings from the study, which includes: • Summarizing the demographic findings in order to describe the characteristics of church members …

Northern-Asian Pacific Division Report: Global Church Member Survey 2017-2018, Petr A. Činčala, Shannon M. Trecartin, Gustavo Emanoel, Christie Chui-Shan Chow

Faculty Publications

This report is the first examination of the Northern-Asian Pacific Division 2017-2018 Global Church Member Survey (GCMS) data. The research team worked closely with the metaanalysis team to ensure consistent implementation of the research protocol and consistent use of the questionnaire. A total of 3064 surveys were used from all NSD Unions. The findings of this document are an initial analysis of the data using the latest version of SPSS. The purpose of the Executive Summary is to highlight key findings from the study, which includes: 1. Summarizing the demographic findings in order to describe the characteristics of church members …

Southern Asia Division Report: Global Church Member Survey 2017-2018, Petr A. Činčala, Shannon M. Trecartin, Vara Deepati

Faculty Publications

This report is the first examination of the Southern Asia Division 2017-2018 Global Church Member Survey (GCMS) data. The research team worked closely with the meta-analysis team to ensure consistent implementation of the research protocol and consistent use of the questionnaire. A total of 2981 surveys were used from all SUD Unions. The findings of this document are an initial analysis of the data using the latest version of SPSS. The purpose of the Executive Summary is to highlight key findings from the study, which includes: 1. Summarizing the demographic findings in order to describe the characteristics of church members …

Influence Of Neighboring Clonal-Colonies On Aflatoxin Production By Aspergillus Flavus, Rebecca R. Sweany, Kenneth E. Damann

Faculty Publications

Aspergillus flavus is an ascomycete fungus that infects and contaminates corn, peanuts, cottonseed, and treenuts with acutely toxic and carcinogenic aflatoxins. The ecological function of aflatoxin production is not well understood; though not phytotoxic, aflatoxin may be involved in resisting oxidative stress responses from infection or drought stress in plants. Observation of aflatoxin stimulation in 48-well plates in response to increasing inoculated wells sparked an investigation to determine if A. flavus volatiles influence aflatoxin production in neighboring colonies. Experiments controlling several culture conditions demonstrated a stimulation of aflatoxin production with increased well occupancy independent of pH buffer, moisture, or isolate. …

Nutrition Intervention Using Behavioral Change Communication Without Additional Material Inputs Increased Expenditures On Key Food Groups In Bangladesh, Andrea M. Warren, Edward A. Frongillo, Phuong H. Nguyen, Purnima Menon

Faculty Publications

Background

Behavioral change communication (BCC) promotes skills and knowledge to improve infant and young child feeding, but without additional material inputs, recipients must develop strategies to translate knowledge into action. Using data from the Alive & Thrive initiative in Bangladesh (2010–2014), we aimed to test whether households receiving the intensive intervention (opposed to the nonintensive intervention) increased expenditures on key foods for mothers and children (e.g., foods that were promoted by the intervention and also changed in maternal and child diets).

Methods

The intensive intervention provided interpersonal counseling, community mobilization, and mass media campaigns to promote breastfeeding and complementary feeding. …

Catalysts For Polymer Membrane Fuel Cells, William E. Mustain, Bryan Pivovar

Faculty Publications

No abstract provided.

Granulins Modulate Liquid-Liquid Phase Separation And Aggregation Of Prion-Like C-Terminal Domain Of The Neurodegeneration-Associated Protein Tdp-43, Anukool A. Bhopatkar, Vladimir N. Uversky, Vijay Rangachari

Faculty Publications

Tar DNA binding protein 43 (TDP-43) has emerged as a key player in many neurodegenerative pathologies including frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). Hallmarks of both FTLD and ALS are the toxic cytoplasmic inclusions of the prion-like C-terminal fragments of TDP-43 (TDP-43 CTD), formed upon proteolytic cleavage of full-length TDP-43 in the nucleus and subsequent transport to the cytoplasm. Both full-length TDP-43 and its CTD are also known to form stress granules (SGs) by coacervating with RNA in the cytoplasm during stress and may be involved in these pathologies. Furthermore, mutations in PGRN gene, leading to haploinsufficiency …

Verification Of Cryptocurrency Mining Using Ethereum, Dong Her Shih, Ting Wei Wu, Tzu Hsin Hsu, Po Yuan Shih, David C. Yen

Faculty Publications

With advancement in computer technology, financial technology has also evolved. Blockchain technology has evolved over the past decade; however, this has also resulted in some malicious attacks. To earn mining rewards of a blockchain, a new type of attack, called cryptojacking, has emerged in the online world. This attack uses the computer resources of a victim to obtain mining rewards without user confirmation. However, this monetization model was originally intended to replace advertising as a source of revenue for a website. To resolve such problems, a storage verification architecture based on smart contracts was proposed in the study. The decentralized …

Current Trends In The Pharmacotherapy Of Cataracts, Segewkal H. Heruye, Leonce N.Maffofou Nkenyi, Neetu U. Singh, Dariush Yalzadeh, Kalu K. Ngele, Ya Fatou Njie-Mbye, Sunny E. Ohia, Catherine A. Opere

Faculty Publications

Cataracts, one of the leading causes of preventable blindness worldwide, refers to lens degradation that is characterized by clouding, with consequent blurry vision. As life expectancies improve, the number of people affected with cataracts is predicted to increase worldwide, especially in low-income nations with limited access to surgery. Although cataract surgery is considered safe, it is associated with some complications such as retinal detachment, warranting a search for cheap, pharmacological alternatives to the management of this ocular disease. The lens is richly endowed with a complex system of non-enzymatic and enzymatic antioxidants which scavenge reactive oxygen species to preserve lens …

Media Technology And The Dissemination Of Hate, Fordham University

Faculty Publications

No abstract provided.

Interpretability Of Api Call Topic Models: An Exploratory Study, Puntitra Glendowne, Dae Glendowne

Faculty Publications

Topic modeling is an unsupervised method for discovering semantically coherent combinations of words, called topics, in unstructured text. However, the human interpretability of topics discovered from non-natural language corpora, specifically Windows API call logs, is unknown. Our objective is to explore the coherence of topics and their ability to represent the themes of API calls from malware analysts’ perspective. Three Latent Dirichlet Allocation (LDA) models were fit to a collection of dynamic API call logs. Topics, or behavioral themes, were manually evaluated by malware analysts. The results were compared to existing automated quality measures. Participants were able to accurately determine …

Activist 101 Activities For Pre-Service Teachers, Heather K. Olson Beal, Lauren Burrow, Chrissy Cross, Amber Wagnon

Faculty Publications

This Teaching Note briefly describes three activities that can easily be integrated into any teacher education course.

Simulating Medical Isolation: Communicatively Managing Patient And Medical Team Safety, Elizabeth Spradley, R. Tyler Spradley

Faculty Publications

Reducing hospital acquired or associated infections (HAIs) is a national public health priority. HAIs pose risks to patients, visitors, and medical personnel. To better understand how to communicatively manage safety in medical isolation, data was collected with nursing students simulating medical isolation in a high-fidelity simulation with a medical mannequin with C. difficile. Observations of nursing students and faculty revealed four distinct communication practices: social support, patient education, humor, and storytelling. Conclusions include recommendations to intentionally design these communication practices into high-fidelity medial isolation simulations and scale up these communication practices in routines of safety.