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Targeting Bacterial Transcription Factors For Infection Control: Opportunities And Challenges, Ahmed Al-Tohamy, Anne Grove Jan 2025

Targeting Bacterial Transcription Factors For Infection Control: Opportunities And Challenges, Ahmed Al-Tohamy, Anne Grove

Faculty Publications

The rising threat of antibiotic resistance in pathogenic bacteria emphasizes the need for new therapeutic strategies. This review focuses on bacterial transcription factors (TFs), which play crucial roles in bacterial pathogenesis. We discuss the regulatory roles of these factors through examples, and we outline potential therapeutic strategies targeting bacterial TFs. Specifically, we discuss the use of small molecules to interfere with TF function and the development of transcription factor decoys, oligonucleotides that compete with promoters for TF binding. We also cover peptides that target the interaction between the bacterial TF and other factors, such as RNA polymerase, and the targeting …


Maximum Spread Of Ks,T-Minor-Free Graphs, William Linz, Linyuan Lu, Zhiyu Wang Jan 2025

Maximum Spread Of Ks,T-Minor-Free Graphs, William Linz, Linyuan Lu, Zhiyu Wang

Faculty Publications

The spread of a graph G is the difference between the largest and smallest eigenvalue of the adjacency matrix of G. In this paper, we consider the family of graphs which contain no Ks,t-minor. We show that for any t ≥ s ≥ 2 and sufficiently large n, there is an integer ξt such that the extremal n-vertex Ks,t-minor-free graph attaining the maximum spread is the graph obtained by joining a graph L on (s −1) vertices to the disjoint union of (Formula Presented) copies of Kt and (Formula Presented) isolated vertices. Furthermore, we give an explicit formula for ξt …


Hope For Louisiana’S Coast: From Catastrophic Loss To Transient Gain, Richard Condrey, Brian D. Marx, Frank Saforo, Rudy Bartels Jan 2025

Hope For Louisiana’S Coast: From Catastrophic Loss To Transient Gain, Richard Condrey, Brian D. Marx, Frank Saforo, Rudy Bartels

Faculty Publications

Louisiana’s fifty-billion-dollar coastal restoration plan relies on selected interpretations of a small dataset of coastwide land measurements. In the 1990’s, the plan’s founders used a mathematically impossible interpretation of an improbable manipulation of the initial (1932-1990) dataset to justify their misconceptions regarding natural conditions; delta-switching; and a failing, 60-year restoration goal. In 2017, the dataset was updated to 2016 and used to suggest that land loss had slowed to -28 km2/yr (-1 football field/100 min) since 2010. We find that the dataset does not support this suggestion. Rather, we find the dataset supports our hypothesis that increasing precipitation in the …


Identifying All Matches Of A Rigid Object In An Input Image Using Visible Triangles, Abdullah N. Arslan Jan 2025

Identifying All Matches Of A Rigid Object In An Input Image Using Visible Triangles, Abdullah N. Arslan

Faculty Publications

It has been suggested that for objects identifiable by their corners, every triangle formed by these corner points can serve as a reference for detecting other corner points. This approach enables effective rigid object detection, including partial matches. However, when there are many corner points, the implementation becomes impractical due to excessive memory requirements. To overcome this, we propose a new algorithm that leverages Delaunay triangulation, considering only the triangles generated by the Delaunay triangulation to reduce the complexity of the original approach. Our algorithm is significantly faster and requires significantly less memory, offering a viable solution for large problem …


Indirect Earnings Management, Scott B. Jackson, Jason T. Rasso, Aaron F. Zimbleman Jan 2025

Indirect Earnings Management, Scott B. Jackson, Jason T. Rasso, Aaron F. Zimbleman

Faculty Publications

We hypothesize that managers use their hierarchical role as reviewers of accounting judgments and estimates to manage earnings, which we call indirect earnings management (IEM). Across a series of experiments using highly experienced financial executives as participants, we provide evidence that IEM (1) is likely used by managers to achieve current and future earnings targets, (2) reduces both cognitive dissonance associated with managing earnings and the extent to which managers think that their behaviors constitute earnings management, and (3) is more likely to be used when corporate governance is strong than when corporate governance is weak. The results of this …


Actuator Disk Model For Aeropropulsive Coupling Effects In Vortex Particle Method, Eduardo Alvarez, Vineet Ahuja, Vinod Lakshminarayan, Aaron Perry, Ryan Anderson, Andrew Ning Jan 2025

Actuator Disk Model For Aeropropulsive Coupling Effects In Vortex Particle Method, Eduardo Alvarez, Vineet Ahuja, Vinod Lakshminarayan, Aaron Perry, Ryan Anderson, Andrew Ning

Faculty Publications

Blown lift and distributed electric propulsion aircraft pose strong aeropropulsive coupling effects that cannot be ignored during the early stages of design. In this study, we develop an advanced actuator disk model (ADM) for aeropropulsive coupling effects of ducted fans with the vortex particle method (VPM). The advanced ADM consists of (1) an actuator disk at the rotor plane, (2) a surface vortex sheet modeling the mixing and convection of blade tip vorticity along walls, and (3) a powered wake at the exhaust. With these three components, a propulsion jet with an arbitrary velocity profile is formed and interactions with …


Artificial Intelligence In Educational Research And Scholarship: Seven Framings, Eamon Costello, Giselle Ferreira, Stefan Hrastinski, Jason K. Mcdonald, Ahmed Tlili, George Veletsianos, Victoria I. Marin, Henk Huijser, Sharon Altena Jan 2025

Artificial Intelligence In Educational Research And Scholarship: Seven Framings, Eamon Costello, Giselle Ferreira, Stefan Hrastinski, Jason K. Mcdonald, Ahmed Tlili, George Veletsianos, Victoria I. Marin, Henk Huijser, Sharon Altena

Faculty Publications

In a recent interview (Bender et al., 2025), Professor Emily M. Bender discussed the limitations of technical solutions in addressing harmful Artificial Intelligence (AI) bias. She described a particular point we may reach at which technical solutions stop working, and when we should then widen the lens to ask about the problem framing itself. This is a crucial step in any inquiry that is of concern to both novice and experienced researchers alike: moving from problem-solving to problematisation. This commentary aims to provide educational researchers with a glimpse into the wide array of research problems and problematisation of AI in …


Comparing The Sensitivity And Specificity Of Novel Motor Assessments For Traumatic Brain Injury, Paula K. Johnson, Ariana M. Hedges-Muncy, Erin D. Bigler, Lorie Richards, Steven Knight Charles Jan 2025

Comparing The Sensitivity And Specificity Of Novel Motor Assessments For Traumatic Brain Injury, Paula K. Johnson, Ariana M. Hedges-Muncy, Erin D. Bigler, Lorie Richards, Steven Knight Charles

Faculty Publications

Background: Portable technology that records movements with high accuracy provides potential for sensitive clinical movement tests for individuals who experienced a traumatic brain injury (TBI). Objective: (1)To present impairments assessed using markerless motion capture (MMC) and (2) to compare the sensitivity and specificity of the MMCmediated tests to each other and to common clinical tests. Design: Screening study, using as criterion standard the ability to classify participant with TBI versus control participant. Setting: Research laboratory. Participants: The study included 30 individuals with TBI and 101 control participants. Entry criteria included most recent head injury < 5 years old, no history of movement issues prior to injury, no movement-affecting medications, and sufficient cognitive ability to follow instructions. Interventions: Not applicable. Main Outcome Measures: Performance on MMC-mediated tests and existing clinical analogs. MMC-mediated tests included finger oscillation, simple reaction time, and visually guided movement tasks. For comparison, participants also completed the following clinical tests: Halstead–Reitan finger tapping, simple reaction time test, and Beery Visuomotor Integration test. Impairments were identified as test scores of participants with TBI that fell outside of the 95% interval of control participants’ test scores. Random forest analysis was used to calculate the sensitivity and specificity of MMC and clinical tests according to their ability to correctly classify participants with TBI and control participants. Results: MMC-mediated tests revealed impairments in more participants with TBI than clinical tests in all three TBI groups (mild, repeated, and moderate to severe). Similarly, MMC-mediated tests revealed a higher percentage of scores as impairments than clinical tests in all three groups with TBI. Furthermore, MMC-mediated tests proved more sensitive and more specific than clinical tests (70% versus 50% and 98% versus 93%, respectively). Conclusion: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.


Business Communication And Editing Students’ Evaluations Of Written Error: An Eye-Tracking Study, Matt Baker, Grant Eck, Ana Barraza, Benjamin Duffield Jan 2025

Business Communication And Editing Students’ Evaluations Of Written Error: An Eye-Tracking Study, Matt Baker, Grant Eck, Ana Barraza, Benjamin Duffield

Faculty Publications

Using eye-tracking and interview methods, this study investigates how business communication students and editing students attend to and evaluate writing. Participants reviewed blog posts embedded with errors and judged publication readiness. While both groups visually fixated longer on errors than non-errors, business communication students were more likely to approve error-containing texts for publication. Qualitative data revealed that business communication students prioritized content while editing students prioritized surface-level issues. These findings suggest that disciplinary background informs evaluative standards, even when error-detection behavior is similar. The results carry implications for instruction in business writing and editing, especially concerning collaborative, cross-disciplinary workplace writing.


The Development Of A Rag-Based Artificial Intelligence Research Assistant (Aira), Hamid Vakilzadeh, David A. Wood Jan 2025

The Development Of A Rag-Based Artificial Intelligence Research Assistant (Aira), Hamid Vakilzadeh, David A. Wood

Faculty Publications

No abstract provided.


Signaling Innovation: The Nontax Benefits Of Claiming R&D Tax Credits, Bradford F. Hepfer, Hannah W. Judd, Sarah C. Rice Jan 2025

Signaling Innovation: The Nontax Benefits Of Claiming R&D Tax Credits, Bradford F. Hepfer, Hannah W. Judd, Sarah C. Rice

Faculty Publications

Using the IPO setting, we test whether firms signal the quality of their investments in innovation activities by claiming R&D tax credits. We find the presence and amount of the R&D credit are each associated with lower information asymmetry and with higher investor demand at IPO. Conservatively, we estimate that sample firms realize additional IPO proceeds of 32–45 percent of their creditable R&D expenditures, indicating economically significant non-tax benefits associated with the R&D credit. We verify the R&D credit signal by showing its positive association with firms’ future patenting activity, patent citations, and post-IPO stock returns. Results from these tests …


Psychological Reactance Theory And Tax Evasion Intentions, Diana Falsetta, Brian C. Spilker Jan 2025

Psychological Reactance Theory And Tax Evasion Intentions, Diana Falsetta, Brian C. Spilker

Faculty Publications

This study experimentally examines how tax administration service inefficiencies in the form of tax return processing delays from paper-filed tax returns indirectly affect taxpayer tax evasion intentions through taxpayers’ psychological reactance to the delay. We further consider whether this indirect effect is different when the taxpayer willingly chooses to paper file their tax return versus when the taxpayer is forced to do so. Consistent with Psychological Reactance Theory (PRT), we find that when taxpayers receive delayed refunds, they experience psychological reactance (e.g., anger and frustration with the tax administration) that increases their tax evasion intentions. Further, we find that the …


An House For The Lord: Solomon's Temple And Temple Worship In Ancient Israel, Dan Belnap Jan 2025

An House For The Lord: Solomon's Temple And Temple Worship In Ancient Israel, Dan Belnap

Faculty Publications

It would not be exaggeration to say that at the center of Old Testament history and theology is covenantal worship and the temple. From the Garden of Eden to the altars constructed by Abraham and the patriarchs, and the portable tabernacle of Moses, the concept of sacred space plays a fundamental role throughout biblical history and in the life of ancient Israel. But during the period of the monarchy, it became possible to construct a permanent house for the Lord. Thus, the construction and dedication of the temple are the primary subject within Solomon’s narrative arc. This chapter explores the …


If The Body Keeps The Score, What Happens When You Bring The Body To Work? Exploring The Health Effects Of Trauma On Human Capital, Lisa Jones Christensen, Elizabeth Embry, Arielle Badger Newman, Paul C. Godfrey Jan 2025

If The Body Keeps The Score, What Happens When You Bring The Body To Work? Exploring The Health Effects Of Trauma On Human Capital, Lisa Jones Christensen, Elizabeth Embry, Arielle Badger Newman, Paul C. Godfrey

Faculty Publications

Data reveal that the physical effects of trauma exposure increasingly surface in business, social, and other settings. Exposure to trauma at any point in life can cause employee health concerns, yet many firms do not acknowledge or address this. Herein, we combine trauma theory with human capital theory to explain how manifestations of trauma exposure—hyperarousal, intrusion, and constriction—impact employee health and performance. This article outlines how each manifestation affects human capital deployment, and thus employee performance. It further demonstrates how these human capital deployment issues have individual- and unit-level performance implications. This article offers a theory linking health effects of …


Existing Personal Leadership Prototypes Versus Organizational Leadership Prototypes: How Individuals Manage Tensions Between Leading With Authenticity And Conformity During Their Socialization As Leaders In Organizations, Benjamin M. Galvin, Jeffrey S. Bednar, Archie Bates Jan 2025

Existing Personal Leadership Prototypes Versus Organizational Leadership Prototypes: How Individuals Manage Tensions Between Leading With Authenticity And Conformity During Their Socialization As Leaders In Organizations, Benjamin M. Galvin, Jeffrey S. Bednar, Archie Bates

Faculty Publications

Based on qualitative data collected at the United States Military Academy (West Point), this research enhances our understanding of how individuals manage tensions between leading with authenticity and organizational pressures for conformity, resulting from a lack of alignment between their existing personal leadership prototypes and organizational prototypes of leadership. Our theoretical model moves beyond existing research on leader identity construction− which largely treats individuals as blank slates as they construct who they will be as leaders in organizations− by highlighting how individuals learn to enact a leadership approach during socialization that fits within their personal zone of acceptable authenticity and …


Individual, Family, Peer, And Religious Community Predictors Of Adolescent Religious Deidentification, Sam A. Hardy, Russ Amelang, Michael Goodman Jan 2025

Individual, Family, Peer, And Religious Community Predictors Of Adolescent Religious Deidentification, Sam A. Hardy, Russ Amelang, Michael Goodman

Faculty Publications

This study examined individual, family, and peer religiosity, and religious community supportiveness as predictors of adolescent religious deidentification. The longitudinal study involved two waves of data, two years apart, from U.S. families (1,021 families; religious adolescents from 11–17 years of age), with measures of dimensions of religiosity at Time 1 and changes in religious identification from Time 1 to Time 2. Within each domain, at least one dimension of religiosity at Time 1 predicted religious deidentification at Time 2. Specifically, youth higher in individual, family, and peer religiosity, and religious community supportiveness, were less likely to leave religion. These relations …


Heart Rate Variability And Personality Traits As Predictors Of Arabic Language Proficiency And Gains During Study Abroad In Jordan, Kirk Belnap, Dan P. Dewey, Patrick Steffan, Annika Barrick Bickmore, Khalil Yousef Jan 2025

Heart Rate Variability And Personality Traits As Predictors Of Arabic Language Proficiency And Gains During Study Abroad In Jordan, Kirk Belnap, Dan P. Dewey, Patrick Steffan, Annika Barrick Bickmore, Khalil Yousef

Faculty Publications

High stress predicts mood and anxiety disorders and can necessitate clinical intervention (Steffen et al., 2014). Language learners often experience high stress during intensive study abroad (SA) programs (Dewey et al., 2018), which can hinder communication (Buttaro, 2004; Peck, 1974). Acculturative stress is common among second language (L2) speakers and can coincide with stress related to the inability to communicate one’s thoughts and ideas (Savicki, 2010), further complicating communication. Therefore, reducing stress in immersive settings can be crucial due to the link between stress, L2 use, and psychological wellbeing (Dewaele & Dewaele, 2021). We report an exploratory investigation of the …


Browsing Within An Academic Library, Holt Zaugg, Jillian Bunderson Jan 2025

Browsing Within An Academic Library, Holt Zaugg, Jillian Bunderson

Faculty Publications

Purpose – Browsing library resources is a method long used by researchers to expand their understanding of ill-defined projects and to have serendipitous research discoveries. This study sought to understand the browsing activities of students in an academic library. Design/methodology/approach – The study used two methods. First, a link to an online survey was posted on posters throughout the library inviting students to share their browsing experience. Second, library security officers (student employees) were asked to count the number of people browsing within the stacks as they conducted their hourly walk-throughs of the library. Browsing was broadly defined as anyone …


Instructional Designer Perspectives On The Pursuit Of Quality In Online Course Design, Jason K. Mcdonald, Stephen C. Yanchar Jan 2025

Instructional Designer Perspectives On The Pursuit Of Quality In Online Course Design, Jason K. Mcdonald, Stephen C. Yanchar

Faculty Publications

In this qualitative study we investigated the experiences of instructional designers as they sought to build quality into online courses. Through semi-structured interviews, we explored what enabled and hindered their pursuit of quality, how they experienced their efforts in this regard, what mattered to them, and complexities that accompanied this pursuit. Our analysis of participant experiences suggested four themes: (1) connections between quality and designers’ ability to act autonomously; (2) connections between quality and collaborative, team-based relationships; (3) ambivalence due to tensions between autonomy and collaboration; and (4) ways of coping with limits on autonomy and collaboration. We conclude our …


Testing The Effect Of Speech Separation On Vowel Formant Estimates, Joseph A. Stanley, Lisa Morgan Johnson, Earl Kjar Brown Jan 2025

Testing The Effect Of Speech Separation On Vowel Formant Estimates, Joseph A. Stanley, Lisa Morgan Johnson, Earl Kjar Brown

Faculty Publications

While recent advances in sociophonetic data processing have made it possible to analyze large datasets and audio not originally intended for linguistic analysis, overlapping speech in recordings with multiple speakers continues to be an issue that results in lost data. We evaluate whether current source separation models produce audio that is clean enough to produce reliable measurements for sociophonetic analysis. We compare formant estimates from a pair of pristine recordings and merged-and-separated versions of those same recordings using the Libri2mix, Whamr16K, and WSJ02mix source separation models. Based on auditory inspection of the separated files, visualization of vowel formant estimates, and …


Testing The Effect Of Speaker Diarization And Speech Separation On Vowel Formant Estimates, Joseph A. Stanley, Lisa Morgan Johnson, Earl Kjar Brown Jan 2025

Testing The Effect Of Speaker Diarization And Speech Separation On Vowel Formant Estimates, Joseph A. Stanley, Lisa Morgan Johnson, Earl Kjar Brown

Faculty Publications

No abstract provided.


Correlate Of Savings Attitude And Generational Poverty As Mediated By Financial Literacy: Evidence From Ghana, Adu Bismark Owusu-Sekyere, Williams Kwasi Peprah [email protected] Jan 2025

Correlate Of Savings Attitude And Generational Poverty As Mediated By Financial Literacy: Evidence From Ghana, Adu Bismark Owusu-Sekyere, Williams Kwasi Peprah [email protected]

Faculty Publications

This study examines the mediating role of financial literacy between savings attitudes and generational poverty in Ghana. Generational poverty is a significant issue in Ghana, with a multidimensional poverty rate of 45.6% and a consumer expenditure poverty rate of 23.4%. The problem persists due to low financial literacy and poor savings attitudes, which hinder economic growth and development. The research employed a quantitative methodology, utilizing a series of regression analyses to test the mediation effects of financial literacy. A correlational design was adopted to assess the relationships between the variables. The study’s population included 400 individuals from the five regions …


The Impact Of Covid-19 Pandemic On Economic Convergence Between Developed And Developing Nations, Lucile Sabas, Williams Kwasi Peprah [email protected], Carmelita Troy, Quentin Sahly Jan 2025

The Impact Of Covid-19 Pandemic On Economic Convergence Between Developed And Developing Nations, Lucile Sabas, Williams Kwasi Peprah [email protected], Carmelita Troy, Quentin Sahly

Faculty Publications

This study investigates convergence between developed and developing countries’ GDP during the pre-COVID-19 era (1960-2019) and post-COVID-19 era (2020-2023) using World Bank data and the Augmented Dickey-Fuller (ADF) test. For the pre-COVID period, results show no significant convergence, with an ADF statistic of −1.78 and a P = 0.39, likely due to disparities in industrialization and governance. Similarly, post-COVID results (ADF statistic −1.2, P = 0.67) also suggest no convergence, possibly exacerbated by pandemic-related challenges. The study highlights that structural barriers and the pandemic have hindered economic convergence.


Predation Of A Sperm Whale (Physeter Macrocephalus) By Killer Whales (Orcinus Orca) In Guanaja, Honduras, Gaby M. Ochoa, Eric Angel Ramos, Daniel Gonzalez-Socoloske Jan 2025

Predation Of A Sperm Whale (Physeter Macrocephalus) By Killer Whales (Orcinus Orca) In Guanaja, Honduras, Gaby M. Ochoa, Eric Angel Ramos, Daniel Gonzalez-Socoloske

Faculty Publications

No abstract provided.


Rescuing Teachers From Burnout: Etiology, Symptoms, And Intervention Strategies, Helen Richelle Ceballo-Hernández Jan 2025

Rescuing Teachers From Burnout: Etiology, Symptoms, And Intervention Strategies, Helen Richelle Ceballo-Hernández

Faculty Publications

No abstract provided.


Essential Elements Of Leadership Style That Contribute To Student Achievement, Pardon Mwansa Jan 2025

Essential Elements Of Leadership Style That Contribute To Student Achievement, Pardon Mwansa

Faculty Publications

No abstract provided.


Suicide Awareness And Crisis Planning: Trauma Responsive Techniques For Educators, Dustin Young, Shannon Trecartin Jan 2025

Suicide Awareness And Crisis Planning: Trauma Responsive Techniques For Educators, Dustin Young, Shannon Trecartin

Faculty Publications

No abstract provided.


Suicide Awareness And Crisis Planning: Trauma Responsive Techniques For Educators, Dustin Young, Shannon Trecartin Jan 2025

Suicide Awareness And Crisis Planning: Trauma Responsive Techniques For Educators, Dustin Young, Shannon Trecartin

Faculty Publications

No abstract provided.


Is There A Future For The Missiological Study Of Worldview?, Paulo Oliveira Jan 2025

Is There A Future For The Missiological Study Of Worldview?, Paulo Oliveira

Faculty Publications

No abstract provided.


Phonotactic Behavior Of Male Cricket Acheta Domesticus In Relation To Age And Syllable Period, Dana Husana, Jessica Rim, David Mbungu, Benjamin Navia Jan 2025

Phonotactic Behavior Of Male Cricket Acheta Domesticus In Relation To Age And Syllable Period, Dana Husana, Jessica Rim, David Mbungu, Benjamin Navia

Faculty Publications

No abstract provided.