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Articles 9961 - 9990 of 14394
Full-Text Articles in Entire DC Network
Fluorescent Chemosensors For Toxic Organophosphorus Pesticides: A Review, Sherine O. Obare, Chandrima De, Wen Guo, Tajay L. Haywood, Tova A. Samuels, Clara P. Adams, Noah O. Masika, Desmond H. Murray, Ginger A. Anderson, Keith Campbell, Kenneth Fletcher
Fluorescent Chemosensors For Toxic Organophosphorus Pesticides: A Review, Sherine O. Obare, Chandrima De, Wen Guo, Tajay L. Haywood, Tova A. Samuels, Clara P. Adams, Noah O. Masika, Desmond H. Murray, Ginger A. Anderson, Keith Campbell, Kenneth Fletcher
Faculty Publications
Many organophosphorus (OP) based compounds are highly toxic and powerful inhibitors of cholinesterases that generate serious environmental and human health concerns. Organothiophosphates with a thiophosphoryl (P=S) functional group constitute a broad class of these widely used pesticides. They are related to the more reactive phosphoryl (P=O) organophosphates, which include very lethal nerve agents and chemical warfare agents, such as, VX, Soman and Sarin. Unfortunately, widespread and frequent commercial use of OP-based compounds in agricultural lands has resulted in their presence as residues in crops, livestock, and poultry products and also led to their migration into aquifers. Thus, the design of …
Supporting Wilderness Search And Rescue With Integrated Intelligence: Autonomy And Information At The Right Time And The Right Place, Michael A. Goodrich, Lanny Lin, Bryan S. Morse, Michael Roscheck
Supporting Wilderness Search And Rescue With Integrated Intelligence: Autonomy And Information At The Right Time And The Right Place, Michael A. Goodrich, Lanny Lin, Bryan S. Morse, Michael Roscheck
Faculty Publications
Current practice in Wilderness Search and Rescue (WiSAR) is analogous to an intelligent system designed to gather and analyze information to find missing persons in remote areas. The system consists of multiple parts — various tools for information management (maps, GPS, etc) distributed across personnel with different skills and responsibilities. Introducing a camera-equipped mini-UAV into this task requires autonomy and information technology that itself is an integrated intelligent system to be used by a sub-team that must be integrated into the overall intelligent system. In this paper, we identify key elements of the integration challenges along two dimensions: (a) attributes …
Mobile Element Scanning (Me-Scan) By Targeted High-Throughput Sequencing, David J. Witherspoon, Jinchuan Xing, Yuhua Zhang, W. Scott Watkins, Mark A. Batzer, Lynn B. Jorde
Mobile Element Scanning (Me-Scan) By Targeted High-Throughput Sequencing, David J. Witherspoon, Jinchuan Xing, Yuhua Zhang, W. Scott Watkins, Mark A. Batzer, Lynn B. Jorde
Faculty Publications
Background: Mobile elements (MEs) are diverse, common and dynamic inhabitants of nearly all genomes. ME transposition generates a steady stream of polymorphic genetic markers, deleterious and adaptive mutations, and substrates for further genomic rearrangements. Research on the impacts, population dynamics, and evolution of MEs is constrained by the difficulty of ascertaining rare polymorphic ME insertions that occur against a large background of pre-existing fixed elements and then genotyping them in many individuals.Results: Here we present a novel method for identifying nearly all insertions of a ME subfamily in the whole genomes of multiple individuals and simultaneously genotyping (for presence or …
Characterization Of Aerosol Associated With Enhanced Small Particle Number Concentrations In A Suburban Forested Environment, L. D. Ziemba, Robert J. Griffin, L. D. Cottrell, Pieter J. Beckman, Q. Zhang, Ruth K. Varner, Barkley C. Sive, Huiting Mao, Robert W. Talbot
Characterization Of Aerosol Associated With Enhanced Small Particle Number Concentrations In A Suburban Forested Environment, L. D. Ziemba, Robert J. Griffin, L. D. Cottrell, Pieter J. Beckman, Q. Zhang, Ruth K. Varner, Barkley C. Sive, Huiting Mao, Robert W. Talbot
Faculty Publications
Two elevated particle number/mass growth events associated with Aitken‐mode particles were observed during a sampling campaign (13–29 September 2004) at the Duke University Free‐Air CO2 Enrichment facility, a forested field site located in suburban central North Carolina. Aerosol growth rates between 1.2 and 4.9 nm hr−1 were observed, resulting in net increases in geometric mean diameter of 21 and 37 nm during events. Growth was dominated by addition of oxidized organic compounds. Campaign‐average aerosol mass concentrations measured by an Aerodyne quadrupole aerosol mass spectrometer (Q‐AMS) were 1.9 ± 1.6 (σ), 1.6 ± 1.9, 0.1 ± 0.1, and 0.4 ± 0.4 …
Synthesis And Characterization Of Free-Base, Copper, And Nickel Isocorroles, Giuseppe Pomarico, Xiao Xiao, Sara Nardis, Roberto Paolesse, Frank R. Fronczek, Kevin M. Smith, Yuanyuan Fang, Zhongping Ou, Karl M. Kadish
Synthesis And Characterization Of Free-Base, Copper, And Nickel Isocorroles, Giuseppe Pomarico, Xiao Xiao, Sara Nardis, Roberto Paolesse, Frank R. Fronczek, Kevin M. Smith, Yuanyuan Fang, Zhongping Ou, Karl M. Kadish
Faculty Publications
A series of free-base and metalated isocorroles represented as (TT-n-iso-Cor)H2 and (TT-n-iso-Cor)MII, where n = 5 or 10 and M = Ni or Cu, were synthesized and characterized by electrochemistry and spectroelectrochemistry in CH2Cl2 containing 0.1 M tetra-n-butylammonium perchlorate. The metalation of the free-base macrocycles with CoII, MnIII, or ZnII was also attempted but was unsuccessful. Six isocorroles were isolated and shown to undergo two stepwise oxidations to give π-cation radicals and dications in CH 2Cl2, with the most stable products being obtained in the case of the 10-substituted derivatives. The same isocorroles could also be reduced by one or …
Proactive Parenting Practices During Early Adolescence: A Cluster Approach, Laura M. Padilla-Walker, Katherine J. Christensen, Randal D. Day
Proactive Parenting Practices During Early Adolescence: A Cluster Approach, Laura M. Padilla-Walker, Katherine J. Christensen, Randal D. Day
Faculty Publications
The purpose of the current study was to explore clusters of proactive parenting practices, and how they might vary as a function of parental demographics, the quality of the parent– child relationship, and the traits and behaviors of the adolescent child. Data were taken from the Flourishing Families Project, which includes 500 families with an early adolescent child (M age ¼ 11.49). Findings suggested that there were four clusters of parents, and patterns were similar for mothers and fathers. Findings also suggested that proactive clusters varied primarily as a function of demographics of the parent (e.g., religiosity, ethnicity, education) and …
Abundance And Ecological Significance Of The Clam Rangia Cuneata (Sowerby, 1831) In The Upper Barataria Estuary (Louisiana, Usa), Wai Hing Wong, Nancy N. Rabalais, R. Eugene Turner
Abundance And Ecological Significance Of The Clam Rangia Cuneata (Sowerby, 1831) In The Upper Barataria Estuary (Louisiana, Usa), Wai Hing Wong, Nancy N. Rabalais, R. Eugene Turner
Faculty Publications
We proposed that Rangia cuneata (Sowerby, 1831) is an important estuarine bivalve with ecological significance in three coastal lakes in Barataria Bay, Gulf of Mexico—Lake Cataouatche, Lake Salvador and Lac des Allemands. Our goals were to determine the abundance and distribution of Rangia in these lakes and to measure clearance times to elucidate its potential impacts on phytoplankton communities. The estimated average densities of R. cuneata in Lake Cataouatche, Lake Salvador, and Lac des Allemands were 63, 157, and 107 individuals m−2, respectively, which is 30% lower than that observed in nearby Lake Pontchartrain. The size of clams in Lake …
Spanish Missions In The Indigenous Landscape:A View From Mission Santa Catalina,Baja California, Lee M. Panich
Spanish Missions In The Indigenous Landscape:A View From Mission Santa Catalina,Baja California, Lee M. Panich
Faculty Publications
Mission Santa Catalina was founded on the margins of the Spanish colonial frontier in northern Baja California, but over time it became an important place in the indigenous landscape of the region. Dominican friars established the mission at a crossroads of native interaction, and recent archaeological, archival, and ethnographic research suggests that indigenous mission neophytes continued to engage in dynamic social and economic relationships with other native groups throughout the colonial period. At the same time, however, the diverse native peoples who lived at Santa Catalina formed new bonds to each other and to the lands around the mission itself. …
Host Specificity Tests Of Gratiana Graminea (Coleoptera: Chrysomelidae), A Potential Biological Control Agent Of Tropical Soda Apple, Solanum Viarum (Solanaceae), J. Medal, N. Bustamante, M. Vitorino, L. Beal, W. Overholt, R. Diaz, J. Cuda
Host Specificity Tests Of Gratiana Graminea (Coleoptera: Chrysomelidae), A Potential Biological Control Agent Of Tropical Soda Apple, Solanum Viarum (Solanaceae), J. Medal, N. Bustamante, M. Vitorino, L. Beal, W. Overholt, R. Diaz, J. Cuda
Faculty Publications
Multiple-choice and no-choice tests were conducted at the Department of Agriculture, Division of Plant Industry Quarantine facility in Gainesville, FL to determine the specificity of the Brazilian leaf-beetle Gratiana graminea Klug, a candidate for biological control of Solanum viarum, tropical soda apple. One hundred fifteen plant species in 32 families were included in the feeding-oviposition multiple-choice tests including the target weed and the 5 major cultivated Solanaceae Capsicum annuum L., Lycopersicon sculentum Mill., Nicotiana tabacum L., Solanum melongena L., and Solanum tuberosum L. Eight to 12 plant species, including always the main target weed, growing in 1-gallon pots were simultaneously …
Determination Of Sperm Concentration For Small-Bodied Biomedical Model Fishes By Use Of Microspectrophotometry, Ereene Tan, Huiping Yang, Terrence R. Tiersch
Determination Of Sperm Concentration For Small-Bodied Biomedical Model Fishes By Use Of Microspectrophotometry, Ereene Tan, Huiping Yang, Terrence R. Tiersch
Faculty Publications
The goal of this study was to establish an efficient method for determination of sperm concentration requiring only 1-2 μL of sample by use of microspectrophotometry. The objectives were (1) determination of wavelengths with absorbance profiles appropriate for analysis of sperm suspensions from zebrafish Danio rerio, green swordtail Xiphophorus helleri, and medaka Oryzias latipes collected by crushing of dissected testis or by stripping of live males; (2) generation of standard curves and equations between sperm sample absorbance and sperm concentration estimated by hemocytometer counts; (3) accuracy verification of equations for estimating concentration by microspectrophotometry; and (4) analysis of the precision …
Promoting Physical Activity In Afterschool Programs, Aaron Beighle, Michael W. Beets, Heather E. Erwin, Jennifer Huberty, Justin B. Moore, Megan Stellino
Promoting Physical Activity In Afterschool Programs, Aaron Beighle, Michael W. Beets, Heather E. Erwin, Jennifer Huberty, Justin B. Moore, Megan Stellino
Faculty Publications
No abstract provided.
War Paths, Peace Paths: An Archaeology Of Cooperation And Conflict In Native Eastern North America, By David H. Dye, Charles R. Cobb
War Paths, Peace Paths: An Archaeology Of Cooperation And Conflict In Native Eastern North America, By David H. Dye, Charles R. Cobb
Faculty Publications
A review of War Paths, Peace Paths: an Archaeology of Cooperation and Conflict in Native Eastern North America, by David H. Dye.
Six Cases In Search Of A Decision: The Story Of In Re Marriage Cases, Jean C. Love, Patricia A. Cain
Six Cases In Search Of A Decision: The Story Of In Re Marriage Cases, Jean C. Love, Patricia A. Cain
Faculty Publications
This chapter will appear in the book, Women and the Law Stories, to be published by Foundation Press (Elizabeth Schneider and Stephanie Wildman, eds.) in fall 2010. The chapter provides historical context for the groundbreaking decision in In re Marriage Cases, which, for a time at least, provided marriage equality for same-sex couples in the State of California. The authors discuss the development of the state constitution, the extension of its equality provisions to protect women, the California Supreme Court’s historic ruling in 1948 that extended marriage equality to interracial couples, and the state’s unique history in the advancement of …
Chemical Inhibition Of Caax Protease Activity Disrupts Yeast Ras Localization, Surya P. Mandahar, Emily R. Hildebrandt, William H. Jacobsen, George M. Santangelo, Walter K. Schmidt
Chemical Inhibition Of Caax Protease Activity Disrupts Yeast Ras Localization, Surya P. Mandahar, Emily R. Hildebrandt, William H. Jacobsen, George M. Santangelo, Walter K. Schmidt
Faculty Publications
Proteins possessing a C-terminal CaaX motif, such as the Ras GTPases, undergo extensive post-translational modification that includes attachment of an isoprenoid lipid, proteolytic processing and carboxylmethylation. Inhibition of the enzymes involved in these processes is considered a cancer-therapeutic strategy. We previously identified nine in vitro inhibitors of the yeast CaaX protease Rce1p in a chemical library screen (Manandhar et al., 2007). Here, we demonstrate that these agents disrupt the normal plasma membrane distribution of yeast GFP-Ras reporters in a manner that pharmacologically phenocopies effects observed upon genetic loss of CaaX protease function. Consistent with Rce1p being the in vivo target …
Positive Economic Freedom: An Enabling Role For International Labor Standards In Developing Countries?, Tonia Warnecke, Alex De Ruyter
Positive Economic Freedom: An Enabling Role For International Labor Standards In Developing Countries?, Tonia Warnecke, Alex De Ruyter
Faculty Publications
Approaches to economic development have overemphasized negative economic freedom for multinational corporations at the expense of a majority of the population in developing countries. An inevitable outcome has been the growth of informal sector and “vulnerable” employment in developing countries and entrenchment of existing inequalities. We argue that rather than an emphasis on negative freedom, an emphasis on using labor standards to facilitate positive economic freedom must occur. Labor standards do this not only through the “core” rights of union membership and collective bargaining, but also in addressing substantive (“non-core”) rights at work (wages, working-time, etc.), thereby facilitating positive freedom.
The Course Council: An Example Of Student-Centered Learning, Deborah Himes, Barbara Heise
The Course Council: An Example Of Student-Centered Learning, Deborah Himes, Barbara Heise
Faculty Publications
To promote student-centered learning, a course council was established in a beginning undergraduate nursing course. A student representative was selected by peers to attend a monthly course council meeting with faculty. Representatives were asked to query classmates in their section of eight students regarding opinions, questions, and concerns about the course and then bring those views to the council. In this monthly, small group, open dialogue setting, students spoke freely about experiences in the classroom, laboratory, and clinical settings. The stage was set for reflection, problem solving, and decision making involving students and faculty. Student input led to meaningful course …
Comparison Of A Reduced Carbohydrate And Reduced Fat Diet For Ldl, Hdl, And Vldl Subclasses During 9-Months Of Weight Maintenance Subsequent To Weight Loss, James D. Lecheminant, Bryan K. Smith, Eric C. Westman, Mary C. Vernon, Joseph E. Donnelly
Comparison Of A Reduced Carbohydrate And Reduced Fat Diet For Ldl, Hdl, And Vldl Subclasses During 9-Months Of Weight Maintenance Subsequent To Weight Loss, James D. Lecheminant, Bryan K. Smith, Eric C. Westman, Mary C. Vernon, Joseph E. Donnelly
Faculty Publications
Objectives: This study compared LDL, HDL, and VLDL subclasses in overweight or obese adults consuming either a reduced carbohydrate (RC) or reduced fat (RF) weight maintenance diet for 9 months following significant weight loss. Methods: Thirty-five (21 RC; 14 RF) overweight or obese middle-aged adults completed a 1-year weight management clinic. Participants met weekly for the first six months and bi-weekly thereafter. Meetings included instruction for diet, physical activity, and behavior change related to weight management. Additionally, participants followed a liquid very low-energy diet of ~2092 kJ per day for the first three months of the study. Subsequently, participants followed …
Did I Do That? An Argument For Requiring Pennsylvania To Evaluate The Racial Impact Of Medicaid Policy, Michael Campbell
Did I Do That? An Argument For Requiring Pennsylvania To Evaluate The Racial Impact Of Medicaid Policy, Michael Campbell
Faculty Publications
No abstract provided.
Should Health Policy Focus On Physical Activity Rather Than Obesity?, Richard Weller, Emmanuel Stamatakis, Steven N. Blair, Timothy P. Gill, Louise A. Baur, Lesley A. King
Should Health Policy Focus On Physical Activity Rather Than Obesity?, Richard Weller, Emmanuel Stamatakis, Steven N. Blair, Timothy P. Gill, Louise A. Baur, Lesley A. King
Faculty Publications
No abstract provided.
Intravenous Ibuprofen: The First Injectable Product For The Treatment Of Pain And Fever, P Brandon Bookstaver, April D. Miller, Celeste N. Rudisill, Leann B. Norris
Intravenous Ibuprofen: The First Injectable Product For The Treatment Of Pain And Fever, P Brandon Bookstaver, April D. Miller, Celeste N. Rudisill, Leann B. Norris
Faculty Publications
This paper reviews the current data on the use of the first approved intravenous ibuprofen product for the management of post-operative pain and fever in the United States. The management of acute and post-operative pain and fever with nonsteroidal anti-inflammatory agents (NSAIDs) is well documented. A search in Medline and International Pharmaceutical Abstracts of articles until the end of November 2009 and references of all citations were conducted. Available manufacturer data on file were also analyzed for this report. Several randomized controlled studies have demonstrated the opioid-sparing and analgesic effects of 400 and 800 mg doses of intravenous ibuprofen in …
Mitt Romney’S Religion: A Five Factor Model For Analysis Of Media Representation Of Mormon Identity, Sherry Baker, Joel Campbell
Mitt Romney’S Religion: A Five Factor Model For Analysis Of Media Representation Of Mormon Identity, Sherry Baker, Joel Campbell
Faculty Publications
Mitt Romney’s religion accounted for 50% of all religion-related presidential primary campaign stories in 2007, and 30% of Romney’s total media coverage focused on his Mormon faith. This article reviews that coverage and considers it within the larger historical context of the complex relationship between media and Mormonism throughout the 180-year history of the Church of Jesus Christ of Latter-day Saints. A factorial model (the first in the area of Mormon Media Studies) is proposed by which to document and analyze the wider societal influences that are reflected in media representation of Mormon identity. The model’s 5 factors include the …
Iron-Binding Activity Of Human Iron-Sulfur Cluster Assembly Protein Hisca1, Jianxin Lu, Jacob P. Bitoun, Guoqiang Tan, Wu Wang, Wenguang Min, Huangen Ding
Iron-Binding Activity Of Human Iron-Sulfur Cluster Assembly Protein Hisca1, Jianxin Lu, Jacob P. Bitoun, Guoqiang Tan, Wu Wang, Wenguang Min, Huangen Ding
Faculty Publications
A human homologue of the iron-sulfur cluster assembly protein IscA (hIscA1) has been cloned and expressed in Escherichia coli cells. The UV-visible absorption and EPR (electron paramagnetic resonance) measurements reveal that hIscA1 purified from E. coli cells contains a mononuclear iron centre and that the iron binding in hIscA1 expressed in E. coli cells can be furthermodulated by the iron content in the cell growth medium. Additional studies show that purified hIscA1 binds iron with an iron association constant of approx. 2×1019 M-1, and that the iron-bound hIscA1 is able to provide the iron for the iron-sulfur cluster assembly in …
Lysine-Based Zwitterionic Molecular Micelle For Simultaneous Separation Of Acidic And Basic Proteins Using Open Tubular Capillary Electrochromatography, Leonard Moore, Zorabel M. Lejeune, Candace A. Luces, Arther T. Gates, Min Li, Bilal El-Zahab, Jayne C. Garno, Isiah M. Warner
Lysine-Based Zwitterionic Molecular Micelle For Simultaneous Separation Of Acidic And Basic Proteins Using Open Tubular Capillary Electrochromatography, Leonard Moore, Zorabel M. Lejeune, Candace A. Luces, Arther T. Gates, Min Li, Bilal El-Zahab, Jayne C. Garno, Isiah M. Warner
Faculty Publications
In this work, a zwitterionic molecular micelle, poly-ε-sodium- undecanoyl lysinate (poly-ε-SUK), was synthesized and employed as a coating in open tubular capillary electrochromatography (OT-CEC) for protein separation. The zwitterionic poly-ε-SUK containing both carboxylic acid and amine groups can be either protonated or deprotonated depending on the pH of the background electrolyte; therefore, either an overall positively or negatively charged coating can be achieved. This zwitterionic coating allows protein separations in either normal or reverse polarity mode depending on the pH of the background electrolyte. The protein mixtures contained four basic proteins (lysozyme, cytochrome c, α-chymotrypsinogen A, and ribonuclease A) and …
Nursing Students: Untapped Resource For Running Computerized Patient Simulators, Starla Aragon, Amy Kotter, Patricia K. Ravert, Suzan E. Kardong-Edgren
Nursing Students: Untapped Resource For Running Computerized Patient Simulators, Starla Aragon, Amy Kotter, Patricia K. Ravert, Suzan E. Kardong-Edgren
Faculty Publications
High-fidelity simulation (HFS) is sweeping the nation as a legitimate and exciting new resource for nursing educators. As with most new technologies, HFS is not without its difficulties. It can be a costly program to run and may also cause anxiety among the faculty required for implementation. There is a simple solution to help increase the ease of its implementation: using student workers. This article discusses how using students to help run the simulations can not only reduce overall cost and anxiety associated with this new technology but also increase learning among those participating in HFS.
Advancing The Future Of Physical Activity Guidelines In Canada: An Independent Expert Panel Interpretation Of The Evidence, Antero Kesäniemi, Chris J. Riddoch, Bruce Reeder, Steven N. Blair, Thorkild I. A. Sørensen
Advancing The Future Of Physical Activity Guidelines In Canada: An Independent Expert Panel Interpretation Of The Evidence, Antero Kesäniemi, Chris J. Riddoch, Bruce Reeder, Steven N. Blair, Thorkild I. A. Sørensen
Faculty Publications
The Canadian Society for Exercise Physiology, in partnership with the Public Health Agency of Canada, has initiated a review of their physical activity guidelines to promote healthy active living for Canadian children, youth, adults and older adults; previous guidelines were released in 2002, 2002, 1998 and 1999 respectively. Several background papers from this project were published recently and provide foundation evidence upon which to base new guidelines. Furthermore, comprehensive systematic reviews were completed to ensure a rigorous evaluation of evidence informing the revision of physical activity guidelines for asymptomatic populations. The overall guideline development process is being guided and assessed …
“Pilot Implementation Of An Interdisciplinary Course On Climate Solutions”, Lawrence Quill, Jinny Rhee, Eugene Cordero
“Pilot Implementation Of An Interdisciplinary Course On Climate Solutions”, Lawrence Quill, Jinny Rhee, Eugene Cordero
Faculty Publications
A pilot implementation of an experimental interdisciplinary course on climate solutions was undertaken at San Jose´ State University in the fall semester of 2008. The course, co-taught by seven faculty members from six colleges, was approved for a general education requirement and was open to upperclass students campus-wide. A course with such a breadth of topics and range of student backgrounds was the first of its kind here. The lessons learned from the pilot effort were assessed from student, faculty, and administrative perspectives. The educational benefits to students from the interdisciplinary format were found to be substantial, in addition to …
Performance, Properties And Plasticity Of Identified Oxytocin And Vasopressin Neurones In Vitro, William E. Armstrong, L. Wang, C. Li, R. Teruyama
Performance, Properties And Plasticity Of Identified Oxytocin And Vasopressin Neurones In Vitro, William E. Armstrong, L. Wang, C. Li, R. Teruyama
Faculty Publications
The neurohypophysial hormones oxytocin (OT) and vasopressin (VP) originate from hypothalamic neurosecretory cells in the paraventricular and supraoptic (SON) nuclei. The firing rate and pattern of action potentials arising from these neurones determine the timing and quantity of peripheral hormone release. We have used immunochemical identification of biocytin-filled SON neurones in hypothalamic slices in vitro to uncover differences between OT and VP neurones in membrane and synaptic properties, firing patterns, and plasticity during pregnancy and lactation.In this review, we summarise some recent findings from this approach: (i) VP neuronal excitability is influenced by slow (sDAP) and fast (fDAP) depolarising afterpotentials …
Interaction Of Francisella Asiatica With Tilapia (Oreochromis Niloticus) Innate Immunity, Esteban Soto, Denise Fernandez, Ronald Thune, John P. Hawke
Interaction Of Francisella Asiatica With Tilapia (Oreochromis Niloticus) Innate Immunity, Esteban Soto, Denise Fernandez, Ronald Thune, John P. Hawke
Faculty Publications
Members of the genus Francisella are facultative intracellular bacteria that cause important diseases in a wide variety of animals worldwide, including humans and fish. Several genes that are important for intramacrophage survival have been identified, including the iglC gene, which is found in the iglABCD operon in the Francisella sp. pathogenicity island (FPI). In the present study, we examined the interaction of wild-type Francisella asiatica and a ΔiglC mutant strain with fish serum and head kidney-derived macrophages (HKDM). Both the wild-type and the mutant strains were resistant to killing by normal and heat-inactivated sera. The wild-type F. asiatica is able …
Siamese Cooperates With The Cdh1-Like Protein Ccs52a1 To Establish Endoreplication In Arabidopsis Thaliana Trichomes, Remmy Kasili, Jason D. Walker, L. Alice Simmons, Jing Zhou, Lieven De Veylder, John C. Larkin
Siamese Cooperates With The Cdh1-Like Protein Ccs52a1 To Establish Endoreplication In Arabidopsis Thaliana Trichomes, Remmy Kasili, Jason D. Walker, L. Alice Simmons, Jing Zhou, Lieven De Veylder, John C. Larkin
Faculty Publications
Endoreplication, also known as endoreduplication, is a phyogenetically widespread modified version of the cell cycle in which DNA replication is not followed by cell division. The SIAMESE (SIM) gene of Arabidopsis thaliana encodes the founding member of a novel class of plant-specific cyclin-dependent kinase (CDK) inhibitors and is a key regulator of endoreplication during the development of trichomes (shoot epidermal hairs). Here, we have identified mutations in the CCS52A1 gene as genetic modifiers of the multicellular trichome phenotype of sim mutants. Loss-of-function ccs52A1 mutations dramatically enhance the multicellularity of sim mutants trichomes in double mutants, whereas overexpression of CCS52A1 completely …
Compassion-Focused Reappraisal, Benefit-Focused Reappraisal, And Rumination After An Interpersonal Offense: Emotion-Regulation Implications For Subjective Emotion, Linguistic Responses, And Physiology, Charlotte Vanoyen-Witvliet, Ross W. Knoll, Nova G. Hinman, Paul Deyoung
Compassion-Focused Reappraisal, Benefit-Focused Reappraisal, And Rumination After An Interpersonal Offense: Emotion-Regulation Implications For Subjective Emotion, Linguistic Responses, And Physiology, Charlotte Vanoyen-Witvliet, Ross W. Knoll, Nova G. Hinman, Paul Deyoung
Faculty Publications
This repeated measures psychophysiology experiment studied three responses to a past interpersonal offense (38 females and 33 males). We compared rumination with two offense reappraisal strategies. Compassion-focused reappraisal emphasized the offender's humanity, and interpreted the transgression as evidence of the offender's need for positive transformation. Benefit-focused reappraisal emphasized insights gained or strengths shown in facing the offense. Supporting the manipulations, compassion-focused reappraisal stimulated the most empathy and forgiveness, whereas benefit-focused reappraisal prompted the most benefit language and gratitude. Both reappraisals decreased aroused, negative emotion, and related facial muscle tension at the brow (corrugator). Both reappraisals increased happiness and positive emotion …