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Grid-Enabled Treatment Planning For Proton Therapy Using Monte Carlo Simulations, Ravi Vadapalli, Pablo Yepes, Wayne Newhauser, Roger Lichti Jan 2011

Grid-Enabled Treatment Planning For Proton Therapy Using Monte Carlo Simulations, Ravi Vadapalli, Pablo Yepes, Wayne Newhauser, Roger Lichti

Faculty Publications

Grid computing is an emerging technology that enables computational tasks to be accomplished in a collaborative approach by using a distributed network of computers. The grid approach is especially important for computationally intensive problems that are not tractable with a single computer or even with a small cluster of computers, e.g., radiation transport calculations for cancer therapy. The objective of this work was to extend a Monte Carlo (MC) transport code used for proton radiotherapy to utilize grid computing techniques and demonstrate its promise in reducing runtime from days to minutes. As proof of concept we created the Medical Grid …

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Synthetic Protocols For The Nitration Of Corroles, Giuseppe Pomarico, Frank R. Fronczek, Sara Nardis, Kevin M. Smith, Roberto Paolesse Jan 2011

Synthetic Protocols For The Nitration Of Corroles, Giuseppe Pomarico, Frank R. Fronczek, Sara Nardis, Kevin M. Smith, Roberto Paolesse

Faculty Publications

The modification of peripheral positions of corroles by introduction of nitro groups is an important functionalization of this macrocycle. The nitro substituent strongly influences the corrole behavior leading to the preparation of macrocycles with different properties, which can be of interest for their exploitation as catalysts, sensing layers in chemical sensors or in the field of supramolecular chemistry. In the last few years we have developed different routes for the β-nitration of the corrole ring, and we report here novel synthetic protocols which can allow the formation of tri- and tetra-nitro derivatives, as demonstrated by X-ray analysis. In all of …

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Efficient Synthesis And Reactions Of 1,2-Dipyrrolylethynes, Hillary K. Tanui, Erhong Hao, Moses I. Ihachi, Frank R. Fronczek, Kevin M. Smith, M. Graça H. Vicente Jan 2011

Efficient Synthesis And Reactions Of 1,2-Dipyrrolylethynes, Hillary K. Tanui, Erhong Hao, Moses I. Ihachi, Frank R. Fronczek, Kevin M. Smith, M. Graça H. Vicente

Faculty Publications

Various dipyrroles possess important motifs for construction of pyrrole-containing pigments. A series of 1,2-dipyrrolylethynes (4ad) has been efficiently synthesized using an improved one-pot double Sonagashira coupling from trimethylsilylethyne and various 2-iodopyrroles. The resulting 1,2-dipyrrolylethynes were further transformed into novel indolyl-, ethenyl- and carboranyl-dipyrroles (57) using the Larock indole synthesis, stereoselective catalytic hydrogenation, or B10H14. Indolyl-dipyrroles were found to selectively bind fluoride ions using one pyrrolic and the indolyl NHs, whereas the carboranyl- and ethenyl-dipyrroles are potentially valuable precursors for the synthesis of porphyrin isomers and expanded pigments. © 2011 World Scientific Publishing Company.

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Palladium(0) Catalyzed 2,2′-Bipyrrole Syntheses, Lijuan Jiao, Erhong Hao, Frank R. Fronczek, M. Graça H. Vicente, Kevin M. Smith Jan 2011

Palladium(0) Catalyzed 2,2′-Bipyrrole Syntheses, Lijuan Jiao, Erhong Hao, Frank R. Fronczek, M. Graça H. Vicente, Kevin M. Smith

Faculty Publications

Several 2-iodopyrroles are used in Pd(0) catalyzed homocoupling reactions at room temperature in the presence of water to efficiently synthesize 2,2′-bipyrroles. These 2,2′-bipyrroles are strongly luminous materials and have high fluorescence quantum yields. © 2011 World Scientific Publishing Company.

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Application Of A Novel Boronated Porphyrin (H2Ocp) As A Dual Sensitizer For Both Pdt And Bnct, Ryo Hiramatsu, Shinji Kawabata, Shin Ichi Miyatake, Toshihiko Kuroiwa, Michael W. Easson, M. Graça H. Vicente Jan 2011

Application Of A Novel Boronated Porphyrin (H2Ocp) As A Dual Sensitizer For Both Pdt And Bnct, Ryo Hiramatsu, Shinji Kawabata, Shin Ichi Miyatake, Toshihiko Kuroiwa, Michael W. Easson, M. Graça H. Vicente

Faculty Publications

Background: and Objective Boronated porphyrins have emerged as promising dual sensitizers for use in both photodynamic therapy (PDT) and boron neutron capture therapy (BNCT), by virtue of their known tumor affinity, low cytotoxicity in dark conditions, and easy synthesis with high boron content. Octa-anionic 5,10,15,20-tetra[3,5-(nido-carboranylmethyl)phenyl] porphyrin (H2OCP) is a boronated porphyrin having eight boron clusters linked to the porphyrin ring. To evaluate H2OCP's applicability to both PDT and BNCT, we performed an in vitro and ex vivo study using F98 rat glioma cells. Materials and Methods We examined the time-dependent cellular uptake of H 2OCP by measuring the boron concentration …

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Plasticity Of The Reproductive Axis Caused By Social Status Change In An African Cichlid Fish: Ii. Testicular Gene Expression And Spermatogenesis, Karen P. Maruska, Russell D. Fernald Jan 2011

Plasticity Of The Reproductive Axis Caused By Social Status Change In An African Cichlid Fish: Ii. Testicular Gene Expression And Spermatogenesis, Karen P. Maruska, Russell D. Fernald

Faculty Publications

Reproduction in all vertebrates is controlled by the brain-pituitary-gonad (BPG) axis, which is regulated socially in males of the African cichlid fish Astatotilapia burtoni.Althoughsocial information influences GnRH1 neurons at the apex of the BPG axis, little is known about how the social environment and dominance affects the cellular and molecular composition of the testes to regulate reproductive capacity. We created an opportunity for reproductively suppressed males to ascend in status and then measured changes in gene expression and tissue morphology to discover how quickly the perception of this opportunitycaninfluencethetestes.Ourresultsshowrapid up-regulation ofmRNAlevels ofFSH receptorandseveral steroid receptor subtypes inthetestesduringsocial ascent. In contrast,LHreceptor …

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Virus-Derived Sirnas And Pirnas In Immunity And Pathogenesis, Shou Wei Ding, Rui Lu Jan 2011

Virus-Derived Sirnas And Pirnas In Immunity And Pathogenesis, Shou Wei Ding, Rui Lu

Faculty Publications

Cellular organisms have evolved related pathways for the biogenesis and function of small interfering RNAs (siRNAs), microRNAs and PIWI-interacting RNAs (piRNAs). These distinct classes of small RNAs guide specific gene silencing at both transcriptional and posttranscriptional levels by serving as specificity determinants. Small RNAs of virus and host origins have been found to modulate virus-host interactions by RNA interference (RNAi), leading to antiviral immunity or viral pathogenesis. Deep sequencing-based profiling of virus-derived small RNAs as products of host immune recognition not only allowed us to gain insight into the expansion and functional specialization of host factors involved in the antiviral …

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Automated Scanning Probe Lithography With N-Alkanethiol Self-Assembled Monolayers On Au(111): Application For Teaching Undergraduate Laboratories, Treva T. Brown, Zorabel M. Lejeune, Kai Liu, Sean Hardin, Jie Ren Li, Kresimir Rupnik, Jayne C. Garno Jan 2011

Automated Scanning Probe Lithography With N-Alkanethiol Self-Assembled Monolayers On Au(111): Application For Teaching Undergraduate Laboratories, Treva T. Brown, Zorabel M. Lejeune, Kai Liu, Sean Hardin, Jie Ren Li, Kresimir Rupnik, Jayne C. Garno

Faculty Publications

Controllers for scanning probe instruments can be programmed for automated lithography to generate desired surface arrangements of nanopatterns of organic thin films, such as n-alkanethiol self-assembled monolayers (SAMs). In this report, atomic force microscopy (AFM) methods of lithography known as nanoshaving and nano-grafting are used to write nanopatterns within organic thin films. Commercial instruments provide software to control the length, direction, speed, and applied force of the scanning motion of the tip. For nanoshaving, higher forces are applied to an AFM tip to selectively remove regions of the matrix monolayer, exposing bare areas of the gold substrate. Nanografting is accomplished …

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Oncogenic Potential Of Yin Yang 1 Mediated Through Control Of Imprinted Genes, Michelle M. Thiaville, Joomyeong Kim Jan 2011

Oncogenic Potential Of Yin Yang 1 Mediated Through Control Of Imprinted Genes, Michelle M. Thiaville, Joomyeong Kim

Faculty Publications

The transcription factor Yin Yang (YY) 1 is one of the most evolutionarily well-conserved DNA binding proteins that is ubiquitously expressed among different tissue types. YY1 functions as a critical regulator for a diverse set of genes, making its role in the cancerous environment elusive. Recent studies have demonstrated that clusters of YY1 binding sites are overrepresented in imprinted gene loci. These clustered binding sites may function as a molecular rheostat with respect to YY1 protein levels. YY1 levels were documented to be altered in various tumor tissues in conjunction with the transcriptional levels of the imprinted genes it regulates. …

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A Multiple Additive Regression Tree Analysis Of Three Exposure Measures During Hurricane Katrina, Andrew Curtis, Bin Li, Brian D. Marx, Jacqueline W. Mills, John Pine Jan 2011

A Multiple Additive Regression Tree Analysis Of Three Exposure Measures During Hurricane Katrina, Andrew Curtis, Bin Li, Brian D. Marx, Jacqueline W. Mills, John Pine

Faculty Publications

This paper analyses structural and personal exposure to Hurricane Katrina. Structural exposure is measured by flood height and building damage; personal exposure is measured by the locations of 911 calls made during the response. Using these variables, this paper characterises the geography of exposure and also demonstrates the utility of a robust analytical approach in understanding health-related challenges to disadvantaged populations during recovery. Analysis is conducted using a contemporary statistical approach, a multiple additive regression tree (MART), which displays considerable improvement over traditional regression analysis. By using MART, the percentage of improvement in R-squares over standard multiple linear regression ranges …

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Positional Identification Of Variants Of Adamts16 Linked To Inherited Hypertension, Bina Joe, Yasser Saad, Seema Dhindaw, Norman H. Lee, Bryan C. Frank, Ovokeraye H. Achinike, Truong V. Luu, Kathirvel Gopalakrishnan, Edward J. Toland, Phyllis Farms, Shane Yerga-Woolwine, Ezhilarasi Manickavasagam, John P. Rapp, Michael R. Garrett, David Coe, Suneel S. Apte, Tuomo Rankinen, Louis Pérusse, Georg B. Ehret, Santhi K. Ganesh, Richard S. Cooper, Ashley O'Connor, Treva Rice, Alan B. Weder, Aravinda Chakravarti, Dabeeru C. Rao, Claude Bouchard Jan 2011

Positional Identification Of Variants Of Adamts16 Linked To Inherited Hypertension, Bina Joe, Yasser Saad, Seema Dhindaw, Norman H. Lee, Bryan C. Frank, Ovokeraye H. Achinike, Truong V. Luu, Kathirvel Gopalakrishnan, Edward J. Toland, Phyllis Farms, Shane Yerga-Woolwine, Ezhilarasi Manickavasagam, John P. Rapp, Michael R. Garrett, David Coe, Suneel S. Apte, Tuomo Rankinen, Louis Pérusse, Georg B. Ehret, Santhi K. Ganesh, Richard S. Cooper, Ashley O'Connor, Treva Rice, Alan B. Weder, Aravinda Chakravarti, Dabeeru C. Rao, Claude Bouchard

Faculty Publications

No abstract provided.

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Five Blood Pressure Loci Identified By An Updated Genome-Wide Linkage Scan: Meta-Analysis Of The Family Blood Pressure Program, Jeannette Simino, Gang Shi, Rezart Kume, Karen Schwander, Michael A. Province, C. Charles Gu, Sharon Kardia, Aravinda Chakravarti, Georg Ehret, Richard A. Olshen, Stephen T. Turner, Low Tone Ho, Xiaofeng Zhu, Cashell Jaquish, Dina Paltoo, Richard S. Cooper, Alan Weder, J. David Curb, Eric Boerwinkle, Steven C. Hunt, Dabeeru C. Rao Jan 2011

Five Blood Pressure Loci Identified By An Updated Genome-Wide Linkage Scan: Meta-Analysis Of The Family Blood Pressure Program, Jeannette Simino, Gang Shi, Rezart Kume, Karen Schwander, Michael A. Province, C. Charles Gu, Sharon Kardia, Aravinda Chakravarti, Georg Ehret, Richard A. Olshen, Stephen T. Turner, Low Tone Ho, Xiaofeng Zhu, Cashell Jaquish, Dina Paltoo, Richard S. Cooper, Alan Weder, J. David Curb, Eric Boerwinkle, Steven C. Hunt, Dabeeru C. Rao

Faculty Publications

Background A preliminary genome-wide linkage analysis of blood pressure in the Family Blood Pressure Program (FBPP) was reported previously. We harnessed the power and ethnic diversity of the final pooled FBPP dataset to identify novel loci for blood pressure thereby enhancing localization of genes containing less common variants with large effects on blood pressure levels and hypertension.MethodsWe performed one overall and 4 race-specific meta-analyses of genome-wide blood pressure linkage scans using data on 4,226 African-American, 2,154 Asian, 4,229 Caucasian, and 2,435 Mexican-American participants (total N = 13,044). Variance components models were fit to measured (raw) blood pressure levels and two …

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Reverse Causation And Illness-Related Weight Loss In Observational Studies Of Body Weight And Mortality, Katherine M. Flegal, Barry I. Graubard, David F. Williamson, Richard S. Cooper Jan 2011

Reverse Causation And Illness-Related Weight Loss In Observational Studies Of Body Weight And Mortality, Katherine M. Flegal, Barry I. Graubard, David F. Williamson, Richard S. Cooper

Faculty Publications

In studies of weight and mortality, the construct of reverse causation has come to be used to imply that the exposure-outcome relation is biased by weight loss due to preexisting illness. Observed weight-mortality associations are sometimes thought to result from this bias. Evidence for the occurrence of such bias is weak and inconsistent, suggesting that either the analytical methods used have been inadequate or else illness-related weight loss is not an important source of bias. Deleting participants has been the most frequent approach to control possible bias. As implemented, this can lead to deletion of almost 90% of all deaths …

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Source Reduction Behavior As An Independent Measurement Of The Impact Of A Public Health Education Campaign In An Integrated Vector Management Program For The Asian Tiger Mosquito, Kristen Bartlett-Healy, George Hamilton, Sean Healy, Taryn Crepeau, Isik Unlu, Ary Farajollahi, Dina Fonseca, Randy Gaugler, Gary G. Clark, Daniel Strickman Jan 2011

Source Reduction Behavior As An Independent Measurement Of The Impact Of A Public Health Education Campaign In An Integrated Vector Management Program For The Asian Tiger Mosquito, Kristen Bartlett-Healy, George Hamilton, Sean Healy, Taryn Crepeau, Isik Unlu, Ary Farajollahi, Dina Fonseca, Randy Gaugler, Gary G. Clark, Daniel Strickman

Faculty Publications

The goal of this study was to evaluate the effectiveness of a public health educational campaign to reduce backyard mosquito-larval habitats. Three communities each, within two New Jersey counties, were randomly selected to receive: (1) both education and mosquito control, (2) education only, and (3) no education or mosquito control. Four separate educational events included a 5-day elementary school curriculum in the spring, and three door to door distributions of educational brochures. Before and after each educational event, the numbers of mosquito-larval container habitats were counted in 50 randomly selected homes per study area. Container surveys allowed us to measure …

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Influence Of Cortisol On The Attachment And Metamorphosis Of Larval Utterbackia Imbecillis On Bluegill Sunfish (Lepomis Macrochirus), Benjamin Dubansky, Brian Whitaker, Fernando Galvez Jan 2011

Influence Of Cortisol On The Attachment And Metamorphosis Of Larval Utterbackia Imbecillis On Bluegill Sunfish (Lepomis Macrochirus), Benjamin Dubansky, Brian Whitaker, Fernando Galvez

Faculty Publications

The larvae of unionid freshwater mussels (i.e., glochidia) undergo a parasitic stage requiring their attachment to the external epithelia of fish hosts, where they metamorphose into free-living juveniles. We describe the physiological effects in bluegill sunfish (Lepomis macrochirus) of infection with glochidia from the paper pondshell (Utterbackia imbecillis). Glochidia accumulation on bluegill increased dramatically at concentrations of 2000 glochidia liter-1 and above, reaching a maximum attachment density of about 30 glochidia g-1 fish at 4000 glochidia liter-1. Plasma cortisol was the most sensitive indicator of biological effect to glochidial exposure, increasing significantly in hosts exposed to 2000 glochidia liter-1 or …

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Outlook For Development Of High-Throughput Cryopreservation For Small-Bodied Biomedical Model Fishes, Terrence R. Tiersch, Huiping Yang, E. Hu Jan 2011

Outlook For Development Of High-Throughput Cryopreservation For Small-Bodied Biomedical Model Fishes, Terrence R. Tiersch, Huiping Yang, E. Hu

Faculty Publications

With the development of genomic research technologies, comparative genome studies among vertebrate species are becoming commonplace for human biomedical research. Fish offer unlimited versatility for biomedical research. Extensive studies are done using these fish models, yielding tens of thousands of specific strains and lines, and the number is increasing every day. Thus, high-throughput sperm cryopreservation is urgently needed to preserve these genetic resources. Although high-throughput processing has been widely applied for sperm cryopreservation in livestock for decades, application in biomedical model fishes is still in the concept-development stage because of the limited sample volumes and the biological characteristics of fish …

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Sperm Quality Assessments For Endangered Razorback Suckers Xyrauchen Texanus, Jill A. Jenkins, Bruce E. Eilts, Amy M. Guitreau, Chester R. Figiel, Rassa O. Draugelis-Dale, Terrence R. Tiersch Jan 2011

Sperm Quality Assessments For Endangered Razorback Suckers Xyrauchen Texanus, Jill A. Jenkins, Bruce E. Eilts, Amy M. Guitreau, Chester R. Figiel, Rassa O. Draugelis-Dale, Terrence R. Tiersch

Faculty Publications

Flow cytometry (FCM) and computer-assisted sperm motion analysis (CASA) methods were developed and validated for use with endangered razorback suckers Xyrauchen texanus collected (nZ64) during the 2006 spawning season. Sperm motility could be activated within osmolality ranges noted during milt collections (here 167-343 mOsm/kg). We hypothesized that sperm quality of milt collected into isoosmotic (302 mOsm/kg) or hyperosmotic (500 mOsm/kg) Hanks' balanced salt solution would not differ. Pre-freeze viabilities were similar between osmolalities (79%G6 (S.E.M.) and 76%G7); however, post-thaw values were greater in hyperosmotic buffer (27%G3 and 12%G2; PZ0.0065), as was mitochondrial membrane potential (33%G4 and 13%G2; PZ0.0048). Visual estimates …

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Anxiety, Substance Use, And Their Co-Occurrence: Advances In Clinical Science, Michael J. Zvolensky, Julia D. Buckner, Peter J. Norton, Jasper A.J. Smits Jan 2011

Anxiety, Substance Use, And Their Co-Occurrence: Advances In Clinical Science, Michael J. Zvolensky, Julia D. Buckner, Peter J. Norton, Jasper A.J. Smits

Faculty Publications

Research and clinical literatures are replete with examples that psychological disorders are related to drug use, abuse, and dependence. The preponderance of scientific work addressing relations among psychopathological processes and drug use, abuse, and dependence has been focused primarily on psychotic disorders, major depression, antisocial personality disorder, and attention deficit hyperactivity disorder. This corpus of empirical work has indicated that there are clinically meaningful relations among particular types of psychopathology and the onset and maintenance of substance use behaviors and disorders and, in turn, that substance use and use-related problems can impact vulnerability for psychopathology. Within this public health context, …

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Smoking Behavior And Alcohol Consumption In Individuals With Panic Attacks, Amanda R. Mathew, Peter J. Norton, Michael J. Zvolensky, Julia D. Buckner, Jasper A.J. Smits Jan 2011

Smoking Behavior And Alcohol Consumption In Individuals With Panic Attacks, Amanda R. Mathew, Peter J. Norton, Michael J. Zvolensky, Julia D. Buckner, Jasper A.J. Smits

Faculty Publications

Individuals with anxiety often report greater smoking and drinking behaviors relative to those without a history of anxiety. In particular, smoking and alcohol use have been directly implicated among individuals experiencing panic attacks, diagnosed with panic disorder, or high on panic-relevant risk factors such as anxiety sensitivity. Less is known, however, about specific features of panic that may differentiate among those who do or do not use cigarettes or alcohol. The purpose of the current study was to replicate previous research findings of an association between panic symptomatology, cigarette smoking, and alcohol consumption, as well as extend findings by examining …

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Repeatability And Number Of Growing Seasons For The Selection Of Custard Apple Progenies, Julio César Dovale, Paulo Sérgio Lima E Silva, Gustavo Sessa Fialho, Keny Henrique Mariguele, Roberto Fritsche-Neto Jan 2011

Repeatability And Number Of Growing Seasons For The Selection Of Custard Apple Progenies, Julio César Dovale, Paulo Sérgio Lima E Silva, Gustavo Sessa Fialho, Keny Henrique Mariguele, Roberto Fritsche-Neto

Faculty Publications

This study aimed to estimate the repeatability coefficient and determine the minimum number of samples required for effective selection for yield of custard apple. Twenty progenies were evaluated in randomized blocks, five replications and four plants per plot. The fruits were collected, counted and weighed every two days of the year. Estimates of the repeatability coefficients were obtained by the methods of analysis of variance - ANOVA and principal components - PC. The estimates from the repeatability analysis of biennial data are higher than those based on individual years. The estimates of the PC method were accurate even in the …

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Evaluation Of Dry Matter, Protein, Starch, Sucrose, Β-Carotene, Iron, Zinc, Calcium, And Magnesium In East African Sweetpotato [Ipomoea Batatas (L.) Lam] Germplasm, Silver Tumwegamire, Regina Kapinga, Patrick R. Rubaihayo, Don R. Labonte, Wolfgang J. Grüneberg, Gabriela Burgos, Thomas Zum Felde, Rosemary Carpio, Elke Pawelzik, Robert O.M. Mwanga Jan 2011

Evaluation Of Dry Matter, Protein, Starch, Sucrose, Β-Carotene, Iron, Zinc, Calcium, And Magnesium In East African Sweetpotato [Ipomoea Batatas (L.) Lam] Germplasm, Silver Tumwegamire, Regina Kapinga, Patrick R. Rubaihayo, Don R. Labonte, Wolfgang J. Grüneberg, Gabriela Burgos, Thomas Zum Felde, Rosemary Carpio, Elke Pawelzik, Robert O.M. Mwanga

Faculty Publications

The present study evaluated selected East African (EA) sweetpotato varieties for storage root dry matter and nutrient content and obtained information on the potential contributions of the varieties to alleviate vitamin A and mineral deficiencies. Roots obtained from 89 farmer (white- and orange-fleshed) varieties and one introduced variety ('Resisto') were analyzed for storage root quality using near-infrared reflectance spectroscopy technology. Location differences were only significant for starch content. The σ2G variance was significant (P < 0.01) for all the traits except sucrose content. Overall, the farmer varieties had higher dry matter, higher starch, and lower sucrose contents than the control clone, 'Resisto'. It is these qualities that make sweetpotato attractive as a starchy staple in EA. A low population's mean β-carotene content (19.0 ppm)was observed.However, deep orange-fleshed farmer varieties, 'Carrot_C', 'Ejumula', 'Carrot Dar', 'Mayai', and 'Zambezi', had β-carotene content that can meet 350% or greater of recommended daily allowance (RDA) with 250-g serving to a 5- to 8-year-old child. More but light orange-fleshed farmer varieties 'K-118', 'K-134', 'K-46', 'KMI61', 'MLE162 Nakahi', 'PAL161', 'Sowola6', 'Sponge', 'SRT34 Abuket2', 'SRT35 Anyumel', 'SRT52', and 'Sudan' can provide 50% to 90% RDA of pro-vitamin A for the child. The root minerals' content was generally low except for magnesium whose content can meet 50% or greater RDA in many farmer varieties. However, in areas with high sweetpotato consumption, varieties 'Carrot_C', 'Carrot Dar', 'KRE nylon', 'MLE163 Kyebandula', and 'SRT49 Sanyuzameza' can make good intakes of iron, zinc, calcium, and magnesium. In conclusion, some EA farmer varieties can contribute greatly to alleviation of vitamin A deficiency and substantial mineral intakes.

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Responding To Our Own Transgressions: An Experimental Writing Study Of Repentance, Offense Rumination, Self-Justification, And Distraction, Charlotte Vanoyen-Witvliet, Nova G. Hinman, Julie J. Exline, Timothy Brandt Jan 2011

Responding To Our Own Transgressions: An Experimental Writing Study Of Repentance, Offense Rumination, Self-Justification, And Distraction, Charlotte Vanoyen-Witvliet, Nova G. Hinman, Julie J. Exline, Timothy Brandt

Faculty Publications

This between-subjects experiment focused on offender responses to their past interpersonal transgressions in self-identified Christian undergraduates (55 M, 85 F). Participants completed pre-post measures for one of four randomly assigned 20-minute writing conditions: repentance (i.e., writing about constructive sorrow, apology, restitution, behavior change), offense rumination (i.e., negative wallowing), self-justification (i.e., externalizing blame, minimizing costs), or distraction (i.e., daily details). Offense rumination and repentance writing included the most cost-oriented language; rumination had the most negative emotion language. Mixed within (pre vs. post) X between group ANOVA interactions yielded theoretically meaningful results. Repentance reduced self-condemnation and regret while increasing conciliatory motivations toward …

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Discourse Norms As Default Rules: Structuring Corporate Speech To Multiple Stakeholders, David Yosifon Jan 2011

Discourse Norms As Default Rules: Structuring Corporate Speech To Multiple Stakeholders, David Yosifon

Faculty Publications

This Article analyzes corporate speech problems through the framework of corporate law. The focus here is on the "discourse norms" that regulate corporate speech to various corporate stakehold-ers, including shareholders, workers, and consumers. I argue that these "discourse norms" should be understood as default terms in the "nexus-of-contracts" that comprises the corporation. Having reviewed the failure of corporate law as it bears on the interests of non-shareholding stakeholders such as workers and consumers, I urge the adoption of prescriptive discourse norms as an approach to reforming corporate governance in a socially useful manner.

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Predicting Patent Litigation, Colleen Chien Jan 2011

Predicting Patent Litigation, Colleen Chien

Faculty Publications

Patent lawsuits are disruptive, unpredictable, and costly. The inability to anticipate patent litigation makes it practically uninsurable, exposes companies to late-stage suits, and drives companies to rapidly accumulate patents in order to ward off litigation. This article confronts this systemic problem, by examining the factors that lead a particular patent to be litigated – only around 1% of patents ever is. It relates the eventual litigation of a patent to earlier events in the patent’s life, including changes in ownership of the patent (assignments, transfers, and changes in owner size), continued investment in the patent (reexamination, maintenance fees), securitization of …

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Beyond The Doctrine: Five Questions That Will Determine The Aca's Constitutional Fate, Bradley W. Joondeph Jan 2011

Beyond The Doctrine: Five Questions That Will Determine The Aca's Constitutional Fate, Bradley W. Joondeph

Faculty Publications

No abstract provided.

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The Impact Of Cigna V. Amara On Erisa Reimbursement Claims, Roger Baron, Marilyn Trefz Jan 2011

The Impact Of Cigna V. Amara On Erisa Reimbursement Claims, Roger Baron, Marilyn Trefz

Faculty Publications

No abstract provided.

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Consumer Protection And Erisa, Roger Baron Jan 2011

Consumer Protection And Erisa, Roger Baron

Faculty Publications

No abstract provided.

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Themes And Persuasion, Jonathan Van Patten Jan 2011

Themes And Persuasion, Jonathan Van Patten

Faculty Publications

No abstract provided.

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The Role Of Public Comment In The Administrative Agency Process: A Case Study Of The Rulemaking Process Of One South Dakota Agency, Patrick Garry, Candice J. Spurlin, Jami Bishop, Logan Hollers, Joseph Boyle Jan 2011

The Role Of Public Comment In The Administrative Agency Process: A Case Study Of The Rulemaking Process Of One South Dakota Agency, Patrick Garry, Candice J. Spurlin, Jami Bishop, Logan Hollers, Joseph Boyle

Faculty Publications

No abstract provided.

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Amicus Briefs In Indian Law: The Case Of Plains Commerce Bank V. Long Family Land And Cattle Co., Inc., ( Part Ii Of South Dakota Law Review Trilogy), Frank Pommersheim Jan 2011

Amicus Briefs In Indian Law: The Case Of Plains Commerce Bank V. Long Family Land And Cattle Co., Inc., ( Part Ii Of South Dakota Law Review Trilogy), Frank Pommersheim

Faculty Publications

No abstract provided.

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