Digital Commons Network^™

A Longitudinal Evaluation Of Personalized Intrinsic Network Topography And Cognitive Decline In Parkinson's Disease, Renxi Li, Vincent Pozorski, Kevin Dabbs, Maureen Haebig, Christopher R. Cox, Colleen Pletcher, Alexandra Wey, Amy Barzgari, Frances Theisen, Ozioma Okonkwo, Catherine L. Gallagher

Faculty Publications

Resting state functional magnetic resonance imaging (R-fMRI) offers insight into how synchrony within and between brain networks is altered in disease states. Individual and disease-related variability in intrinsic connectivity networks may influence our interpretation of R-fMRI data. We used a personalized approach designed to account for individual variation in the spatial location of correlation maxima to evaluate R-fMRI differences between Parkinson's disease (PD) patients who showed cognitive decline, those who remained cognitively stable and cognitively stable controls. We compared fMRI data from these participant groups, studied at baseline and 18 months later, using both network-based statistics (NBS) and calculations of …

Potential Effects Of Traffic Noise On Anuran Call Characteristics In Louisiana, Usa During Winter, Jane M. Kunberger, Ty J. Price, Chloe Crawford, Allison A. Vestal-Laborde, Ashley M. Long

Faculty Publications

Urban environments expose wildlife to levels of anthropogenic noise they would not experience in rural areas (e.g., traffic noise), and research suggests that many species adjust their acoustic signals for optimal transmission in urban soundscapes. However, our understanding of anuran (order Anura) responses to noise pollution in urban environments of the southeastern United States is limited, particularly for species that can breed during winter. Our goal was to examine how vocal anuran advertisement call characteristics during winter varied with increasing distance from roadways in bottomland hardwoods of Louisiana, USA. We deployed acoustic recording units at two sites (i.e., rural and …

What's Behind The Dramatic Pre-2020 Declines In Hispanic/Latina Adolescent Childbearing? Decomposing Change By Age, Origin, And Nativity, Reanne Frank, Elizabeth Wildsmith, Rhiannon A. Kroeger, Courtney E. Williams, Akanne Torres Beltran

Faculty Publications

Purpose: To assess whether the large declines in adolescent childbearing among Hispanic adolescents over the period 2000-2019 have been driven by co-occurring changes in the composition of the Hispanic population and, if so, whether they have done so differentially by Hispanic subgroup. Methods: We use birth counts from the United States vital statistics system and population denominators from the United States decennial census long form 5-percent Public Use Microdata and the American Community Survey to conduct a decomposition analysis apportioning observed declines in Hispanic adolescent childbearing to: (1) compositional shifts in nativity, age, and region-of-origin and (2) subgroup changes in …

A Systematic Review On The Path To Inclusive And Sustainable Energy Transitions, Oluwafemi Awolesi, Corinne A. Salter, Margaret Reams

Faculty Publications

This paper surveys the energy literature and systematically reviews the path to an inclusive and sustainable energy transition by exploring factors that drive the current energy transitions, countries with advanced energy transition programs, and the roles of energy literacy and justice in energy transition. Utilizing an exhaustive literature search from 2001 to 2023 via the Scopus database, the study identifies strong policy frameworks, technological advancements, economic incentives, and international collaborations as pivotal factors in successful energy transitions. Case studies from the Nordic countries, Germany, and Poland highlight diverse approaches and significant progress, revealing valuable lessons for global application. Although energy …

Selective Antineoplastic Potential Of Fractionated Caribbean Native Ganoderma Species Extracts On Triple-Negative Breast Cancer Cells, Luz V. Arroyo-Cruz, Sebastián Sagardía-González, Kurt Miller, Taotao Ling, Fatima Rivas, Michelle M. Martínez-Montemayor

Faculty Publications

Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by the absence of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor type 2 expression. It is known for its high malignancy, invasiveness, and propensity for metastasis, resulting in a poor prognosis due to the absence of beneficial therapeutic targets. Natural products derived from mushrooms have gained significant attention in neoplastic therapy due to their potential medicinal properties. The therapeutic potential of Ganoderma lucidum in breast cancer has been highlighted by our group, suggesting its use as an adjuvant treatment. The present study aims to assess the potential antineoplastic …

In Vitro Culture Alters Cell Lineage Composition And Cellular Metabolism Of Bovine Blastocyst, Hao Ming, Mingxiang Zhang, Sandeep Rajput, Deirdre Logsdon, Linkai Zhu, William B. Schoolcraft, Rebecca L. Krisher, Zongliang Jiang, Ye Yuan

Faculty Publications

Profiling bovine blastocyst transcriptome at the single-cell level has enabled us to reveal the first cell lineage segregation, during which the inner cell mass (ICM), trophectoderm (TE), and an undefined population of transitional cells were identified. By comparing the transcriptome of blastocysts derived in vivo (IVV), in vitro from a conventional culture medium (IVC), and in vitro from an optimized reduced nutrient culture medium (IVR), we found a delay of the cell fate commitment to ICM in the IVC and IVR embryos. Developmental potential differences between IVV, IVC, and IVR embryos were mainly contributed by ICM and transitional cells. Pathway …

Secondary School State Athletic Association Health And Safety Policy Development Processes, Susan Yeargin, Rebecca M. Hirschhorn, William M. Adams, Samantha E. Scarneo-Miller

Faculty Publications

Background: The National Federation of State High School Associations provides recommendations regarding health and safety policies; however, policy development is governed at the state level. Given interstate differences in governance, the primary purpose was to describe processes that State High School Athletic Associations (SHSAAs) utilize to develop a new policy. The secondary objective was to determine what methods associations use to implement new policies. Methods: A cross-sectional survey requested SHSAA (n = 51) representatives to report how athlete health and safety policies are introduced, revised, approved, and implemented within their state. The 22-question survey was developed to gather variables for …

Presidential Stories Of Fear: Focusing Congressional Climate Change Mitigation Attention In The United States, Holly L. Peterson, Chad Zanocco

Faculty Publications

Do presidential climate change narratives increase related congressional attention in the United States? Narrative theory says since narratives leverage cognitive heuristics, they should focus policy-making attention in institutions more efficiently than non-narrative statements. This study identifies and tests climate change statements and narratives, including those focused on solutions, or “stories of hope,” and those focused on problems and victims, “stories of fear,” for relationships with congressional attention using time series analysis. Findings suggest a relationship between narrative and hearings, but not for non-narrative statements and hearings. Furthermore, while narratives are related to hearings generally, stories of fear have larger effects, …

Understanding Differential Reductions In Undernutrition Among Districts In Rwanda Through The Perspectives Of Mid-Level And Community Actors On Policy Commitment And Policy Coherence, Elyse Iruhiriye, Edward A. Frongillo Ph.D., Deanna K. Olney, Emmanuel Niyongira, Simeon Nanama, Christine E. Blake Ph.D., Rd, Eugene Rwibasira, Paul Mbonyi

Faculty Publications

Understanding the drivers of improvements in child undernutrition at only the national level can mask subnational differences. This paper aimed to understand the contributions of factors in the enabling environment to observed differences in stunting reduction between districts in Rwanda. In 2017, we conducted 58 semi-structured interviews with mid-level actors (n = 38) and frontline workers (n = 20) implementing Rwanda's multi-sectoral nutrition policy in five districts in which stunting decreased (reduced districts) and five where it increased or stagnated (non-reduced districts) based on Rwanda's 2010 and 2014/15 Demographic and Health Surveys. Mid-level actors are government officials and service providers …

Functional Multivariable Logistic Regression With An Application To Hiv Viral Suppression Prediction, Siyuan Guo, Jiajia Zhang Ph.D., Yichao Wu, Alexander C. Mclain Ph.D., James W. Hardin, Bankole Olatosi Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Motivated by improving the prediction of the human immunodeficiency virus (HIV) suppression status using electronic health records (EHR) data, we propose a functional multivariable logistic regression model, which accounts for the longitudinal binary process and continuous process simultaneously. Specifically, the longitudinal measurements for either binary or continuous variables are modeled by functional principal components analysis, and their corresponding functional principal component scores are used to build a logistic regression model for prediction. The longitudinal binary data are linked to underlying Gaussian processes. The estimation is done using penalized spline for the longitudinal continuous and binary data. Group-lasso is used to …

Legal Support For Local Election Officials, Rebecca Green

Faculty Publications

Local election officials (“LEOs”) face enormous pressure. They must administer elections when a wide swath of the American public has grown mistrustful of their work; they increasingly face ominous personal attacks and threats; they cope with chronic underfunding of elections; and they must navigate frequent changes in the law governing elections. Lawyers provide a critical avenue of support for local election officials. They provide guidance on how to implement legislative mandates and judicial orders; they anticipate and prevent disputes from arising; and they represent election officials when they or their offices are sued—a more common occurrence today than ever. Although …

Characteristics Of Pyrolysis Products Of California Chaparral And Their Potential Effect On Wildland Fires, Mahsa Alizadeh, David R. Weise, Thomas H. Fletcher

Faculty Publications

The aim of this study was to investigate the pyrolysis of selected California foliage and estimate the energy content of the released volatiles to show the significance of the pyrolysis of foliage and its role during wildland fires. While the majority of the volatiles released during the pyrolysis of foliage later combust and promote fire propagation, studies on the energy released from combustion of these compounds are scarce. Samples of chamise (Adenostoma fasciculatum), Eastwood’s manzanita (Arctostaphylos glandulosa), scrub oak (Quercus berberidifolia), hoaryleaf ceanothus (Ceanothus crassifolius), all native to southern California, and sparkleberry …

Persevering Through Communication Challenges: A Qualitative Descriptive Exploration Of Communication Experiences In Aphasia, Tyson G. Harmon, Camille Williams, Garrett Cardon, William S. Evans

Faculty Publications

Background

People with aphasia often experience activity limitations and participation restrictions despite wanting to engage in communication activities that are satisfying and meaningful. Communication partner support, the complexity of the communication environment, and the thoughts and feelings of people with aphasia have important implications for both language processing and communicative participation. The perspectives of PWA about the role that environmental and personal factors (e.g. thoughts and feelings) play in their communication experiences could inform clinical practice.

Aims

To qualitatively explore the communication experiences of people with aphasia and how environmental demands and personal factors (especially emotional responses) affect these experiences. …

Probabilistic Estimation Of Cadence And Walking Speed From Floor Vibrations, Yohanna Mejiacruz, Juan M. Caicedo, Zhaoshuo Jiang, Jean M. Franco

Faculty Publications

Objective: This research aims to extract human gait parameters from floor vibrations. The proposed approach provides an innovative methodology on occupant activity, contributing to a broader understanding of how human movements interact within their built environment. Methods and Procedures: A multilevel probabilistic model was developed to estimate cadence and walking speed through the analysis of floor vibrations induced by walking. The model addresses challenges related to missing or incomplete information in the floor acceleration signals. Following the Bayesian Analysis Reporting Guidelines (BARG) for reproducibility, the model was evaluated through twenty-seven walking experiments, capturing floor vibration and data from Ambulatory Parkinson’s …

Psychometric Properties Of The Modified Parenting Attitudes Measure Among African American Adolescents In Public Housing, Melissa L. Villodas, Andrew Foell, Lisa C. Smith, Mansoo Yu, Henrika Mccoy, Yibin Yang, Ngozi V. Enelamah, Margaret Lombe, Von Nebbitt

Faculty Publications

Valid and reliable measurements reflecting how perceived maternal and paternal parenting practices are similar, different, complementary, or additive in studying youth outcomes are critical for building knowledge on supportive parenting practices for African American youth living in public housing. We examined the psychometric properties of the Parental Attitudes Measure (PAM) which focuses on youths’ attitudes on parenting practices. Data was collected from the perspective of 660 African American youth living in urban public housing across three cities in the northeast and mid-Atlantic region in the United States. Youth reported on their attitudes about maternal and paternal caregivers. Reliability was determined …

Psychometric Properties Of The Modified Parenting Attitudes Measure Among African American Adolescents In Public Housing, Melissa L. Villodas, Andrew Foell, Lisa C. Smith, Mansoo Yu, Henrika Mccoy, Yibin Yang, Ngozi V. Enelamah, Margaret Lombe, Von Nebbitt

Faculty Publications

Valid and reliable measurements reflecting how perceived maternal and paternal parenting practices are similar, different, complementary, or additive in studying youth outcomes are critical for building knowledge on supportive parenting practices for African American youth living in public housing. We examined the psychometric properties of the Parental Attitudes Measure (PAM) which focuses on youths’ attitudes on parenting practices. Data was collected from the perspective of 660 African American youth living in urban public housing across three cities in the northeast and mid-Atlantic region in the United States. Youth reported on their attitudes about maternal and paternal caregivers. Reliability was determined …

Short- And Medium-Term Impacts Of Small-Scale Vegetable Support On Food Security: Evidence From Syria, Ghassan Baliki, Melodie Al Daccache, Hala Ghattas Ph.D., Tilman Brück

Faculty Publications

Small-scale agricultural and horticultural interventions play a critical role in improving nutrition and food security of vulnerable households in peaceful settings. However, scant rigorous evidence exists on the impacts and sustainability of such interventions in conflict settings. In this paper, we address this knowledge gap by analyzing the short- and medium-term impacts of a small-scale vegetable input support program involving asset transfers on food security and diets in war-time Syria. We use longitudinal panel household survey data from a quasi-experimental study collected at three rounds: before, one year, and two years after the horticultural intervention ended. We use propensity score …

Effects Of Single-Session Practice Structure On Motor Skill Acquisition And Alpha And Beta Eeg Oscillations, Aubrey Porter, Ronald Victor Croce, Wayne Smith

Faculty Publications

Background: Although it is known that practicing a motor skill updates the associated internal model, it is still unclear as to how cortical oscillations linked with the motor skill change under differing practice schedules. The current study investigated α- and β-power changes associated with motor skill acquisition. Objectives: Firstly, we investigated the behavioral effects of practice on motor learning and retention during repetitive (RP) and variable (VP) practice schedules on an anticipation timing task. Secondly, we investigated changes in cortical α (10 - 13 Hz) and β (15 - 30 Hz) event-related synchronization and desynchronization (ERS/ERD) under RP and VP …

Effects Of Single-Session Practice Structure On Motor Skill Acquisition And Alpha And Beta Eeg Oscillations, Aubrey Porter, Ronald Victor Croce, Wayne Smith

Faculty Publications

Background: Although it is known that practicing a motor skill updates the associated internal model, it is still unclear as to how cortical oscillations linked with the motor skill change under differing practice schedules. The current study investigated α- and β-power changes associated with motor skill acquisition. Objectives: Firstly, we investigated the behavioral effects of practice on motor learning and retention during repetitive (RP) and variable (VP) practice schedules on an anticipation timing task. Secondly, we investigated changes in cortical α (10 - 13 Hz) and β (15 - 30 Hz) event-related synchronization and desynchronization (ERS/ERD) under RP and VP …

A Microfluidic Approach To Study Variations In Chlamydomonas Reinhardtii Alkaline Phosphatase Activity In Response To Phosphate Availability, Alireza Rahnama, Manibarathi Vaithiyanathan, Luis Briceno-Mena, Travis M. Dugas, Kelly L. Yates, Jose A. Romagnoli, Adam T. Melvin

Faculty Publications

Algal growth depends strongly on phosphorus (P) as a key nutrient, underscoring the significance of monitoring P levels. Algal species display a sensitive response to fluctuations in P availability, notably through the expression of alkaline phosphatase (AP) when challenged with P-depletion. As such, alkaline phosphatase activity (APA) serves as a valuable metric for P availability, offering insights into how algae utilize and fix available P resources. However, current APA quantification methods lack single cell resolution, while also being time- and reagent consuming. Microfluidics offers a promising cost-effective solution to these limitations, providing a platform for precise single-cell analysis. In this …

Under Pressure: The Interplay Of Hypertension And White Matter Hyperintensities With Cognition In Chronic Stroke Aphasia, Jade Hannan, Natalie Busby, Rebecca Roth, Janina Wilmskoetter, Roger Newman-Norlund Ph.D., Chris Rorden, Leonardo Bonilha, Julius Fridriksson Ph.D.

Faculty Publications

While converging research suggests that increased white matter hyperintensity load is associated with poorer cognition, and the presence of hypertension is associated with increased white matter hyperintensity load, the relationship among hypertension, cognition and white matter hyperintensities is not well understood. We sought to determine the effect of white matter hyperintensity burden on the relationship between hypertension and cognition in individuals with post-stroke aphasia, with the hypothesis that white matter hyperintensity load moderates the relationship between history of hypertension and cognitive function. Health history, Fazekas scores for white matter hyperintensities and Wechsler Adult Intelligence Scale Matrix Reasoning subtest scores for …

Self-Administered Mindfulness Interventions Reduce Stress In A Large, Randomized Controlled Multi-Site Study, Alessandro Sparacio, Hans Ijzerman, Ivan Ropovik, Filippo Giorgini, Christoph Spiessens, Bert N. Uchino, Joshua Landvatter, Tracey Tacana, Sandra J. Diller, Jaye L. Derrick, Joahana Segundo, Jace D. Pierce, Robert M. Ross, Zoë Francis, Amanda Laboucane, Christine Ma-Kellams, Maire B. Ford, Kathleen Schmidt, Celia C. Wong, Wendy C. Higgins, Bryant M. Stone, Samantha K. Stanley, Gianni Ribeiro, Paul T. Fuglestad, Valerie Jaklin, Andrea Kübler, Philipp Ziebell, Crystal L. Jewell, Yulia Kovas, Tenzin Urgyen

Faculty Publications

Mindfulness witnessed a substantial popularity surge in the past decade, especially as digitally self-administered interventions became available at relatively low costs. Yet, it is uncertain whether they effectively help reduce stress. In a preregistered (OSF https://doi.org/10.17605/OSF.IO/UF4JZ; retrospective registration at ClinicalTrials.gov NCT06308744) multi-site study (nsites = 37, nparticipants = 2,239, 70.4% women, Mage = 22.4, s.d.age = 10.1, all fluent English speakers), we experimentally tested whether four single, standalone mindfulness exercises effectively reduced stress, using Bayesian mixed-effects models. All exercises proved to be more efficacious than the active control. We observed a mean difference of 0.27 (d = −0.56; 95% confidence …

Interactive Cue Matters: The Moderation Role Of Situational Factors In The Effects Of User Comments On News Sharing, Nicky Chang Bi, Ruonan Zhang, Peigin Chen

Faculty Publications

Communicators often find it challenging to prioritize the public and manage their comments during risk communication. This study explored the effects of comments as interactivity cues on news diffusion while considering situational factors under the framework of the Situational Theory of Problem Solving in the context of the US-China trade conflict. For this purpose, the researchers conducted an experiment to investigate the effects of interactivity cues and public segmentations on news sharing. The findings suggest that comments elicit different news-sharing behaviors among different segments of the public. The aware public shares more news than the activists/active public who are more …

Quantifying Variation Across 16s Rrna Gene Sequencing Runs In Human Microbiome Studies, Andrew J. Hoisington, Christopher E. Stamper, Joseph C. Ellis, Christopher A. Lowry, Lisa A. Brenner

Faculty Publications

Recent microbiome research has incorporated a higher number of samples through more participants in a study, longitudinal studies, and metanalysis between studies. Physical limitations in a sequencing machine can result in samples spread across sequencing runs. Here we present the results of sequencing nearly 1000 16S rRNA gene sequences in fecal (stabilized and swab) and oral (swab) samples from multiple human microbiome studies and positive controls that were conducted with identical standard operating procedures. Sequencing was performed in the same center across 18 different runs. The simplified mock community showed limitations in accuracy, while precision (e.g., technical variation) was robust …

Fighting Erasure And Dispossession In The San Francisco Bay Area: Putting Archaeology To Work For The Muwekma Ohlone Tribe, Lee M. Panich, Monica V. Arellano, Michael Wilcox, Gustavo Flores

Faculty Publications

The Muwekma Ohlone Tribe has long been involved in the archaeology and stewardship of their ancestral homelands, both through their own cultural resource management (CRM) firm and though collaborations with academic and CRM archaeologists. In this article, we build on the past 40 years of archaeological collaborations in the southern San Francisco Bay region and offer examples of how archaeologists can support tribal heritage and environmental stewardship by using the traditional purview of material culture in combination with a broader array of evidence and concerns. As presented in our brief case studies, the Muwekma Ohlone Tribe and scholars are working …

The Acceptability Of Relationship-Centered Communication Partner Training For Couples Impacted By Aphasia: A Mixed Methods Pilot Investigation, Kathryn-Anne Pertab, Tyson G. Harmon, Jonathan Sandberg, Jon L. Pertab, William S. Evans

Faculty Publications

Purpose: This study explored the acceptability and impact of Relationship-Centered Communication Partner Training (RC-CPT) in couples impacted by aphasia. In particular, couples considered whether discussing their relationship roles and responsibilities was important and relevant to the changes they desire. Preliminary quasi-experimental data regarding perceived communication confidence and the marriage relationship were also obtained.

Method: Three couples participated in RC-CPT across two sessions. Surveys were used to measure communication confidence and the marital relationship before and after participation in RC-CPT. The quantitative findings were analyzed using descriptive statistics. Couples also participated in a semi-structured interview about the acceptability of RC-CPT, during …

A Snapshot Of How Mediators Use Technology These Days, John Lande

Faculty Publications

All professional mediators inevitably use technology these days. Indeed, they use it more than they realize. And, with the accelerating rate of technological developments, they generally will use it a lot more in the future. But it's not easy to incorporate technological developments into daily practice and keep up with the rapid pace of change. Part of the challenge is that mediators have their own unique complex practice systems that they aren't fully conscious of. And technology is integrated throughout their systems.

Selection Of Host Plants For Production Of Clanis Bilineata (Lepidoptera: Sphingidae), Xiaofeng Li, Mingming Guo, Kebin Li, Song Li, Honglin Feng, Jiwei Fan

Faculty Publications

Clanis bilineata Walker (Lepidoptera: Sphingidae), a burgeoning edible insect, is experiencing rising demand in China and other regions. Despite this interest, larval production is currently constrained by the limitations of artificial production technologies, particularly the selection of optimal host plants. This study rigorously evaluated the performance of C. bilineatha larvae on four main host plants: round-leaf soybean, pointed-leaf soybean, black locust, and kudzu. Preference tests demonstrated that the larvae were most attracted to black locust (34.76 ± 4.65%), with subsequent preferences for kudzu (25.00 ± 6.12%), round-leaf soybean (23.17 ± 2.79%), and pointed-leaf soybean (14.02 ± 4.74%). No significant preference …

Adaptive Phase I–Ii Clinical Trial Designs Identifying Optimal Biological Doses For Targeted Agents And Immunotherapies, Yong Zang, Beibei Guo, Yingjie Qiu, Hao Liu, Mateusz Opyrchal, Xiongbin Lu

Faculty Publications

Targeted agents and immunotherapies have revolutionized cancer treatment, offering promising options for various cancer types. Unlike traditional therapies the principle of “more is better” is not always applicable to these new therapies due to their unique biomedical mechanisms. As a result, various phase I–II clinical trial designs have been proposed to identify the optimal biological dose that maximizes the therapeutic effect of targeted therapies and immunotherapies by jointly monitoring both efficacy and toxicity outcomes. This review article examines several innovative phase I–II clinical trial designs that utilize accumulated efficacy and toxicity outcomes to adaptively determine doses for subsequent patients and …

Consumer Engagement In Fashion Circularity In China: Exploring Consumer Online Fashion Resale Through The Lens Of Social Practice Theory, Sujun Liu, Chuanlan Liu, Chunmin Lang

Faculty Publications

Fashion resale has emerged as a notable strategy for the fashion industry to reduce its environmental footprint by promoting fashion circularity. Despite extensive research on consumer awareness of resale and the purchase of pre-owned items, there remains a gap in understanding the factors that influence consumers’ participation in resale markets, encompassing both selling and buying practices. Drawing on social practice theory (SPT), this qualitative study examines the nuanced factors influencing consumers’ online resale practices and investigates how online fashion resale practices (OFRPs) have become integrated into their daily consumption patterns. In-depth interviews were conducted with thirty experienced Chinese consumers engaged …